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MDI Health Celebrates Community at 2026 Annual Meeting
BAR HARBOR—MDI Health celebrated the people and partnerships strengthening local healthcare during its 2026 Annual Meeting and Community Celebration, held September 15 at the Bar Harbor Club. The gathering brought together patients, medical staff, employees, trustees, volunteers, supporters, and community partners to recognize the year’s accomplishments and honor those whose contributions make a meaningful difference across the organization and the communities it serves. “This celebration is an opportunity to recognize the extraordinary people who make our work possible,” said Chrissi Maguire, president and CEO of MDI Health. “Their compassion, dedication, and belief in strong local healthcare can be felt throughout our hospital, health centers, Birch Bay Village, and the communities we serve.” During the celebration, MDI Health presented its 2026 Impact Award to Mount Desert Nursing Association (MDNA), recognizing the organization as Community Partner of the Year for providing compassionate, skilled in-home nursing care across Mount Desert Island, Trenton, and Lamoine. “MDNA extends care beyond our walls, helping people remain safely at home, surrounded by the people and places they know and love,” Maguire said. “Its work lies at the intersection of healthcare and community and strengthens our entire healthcare system.” “For 77 years, MDNA has helped our neighbors recover and remain safely at home,” said Amy McVety, MDNA Executive Director. “Our longstanding partnership with MDI Health helps ensure a seamless transition from hospital to home and the continued care patients need. We are grateful for this recognition and especially proud of our talented, hardworking team.” The evening marked a transition in Board leadership. Martha Wagner, PhD, was recognized as she concluded her term as chair of the MDI Health Board of Trustees. Madeleine Braun, PhD, MBA, was introduced as incoming chair. “It is an honor to build on Martha’s leadership and serve an organization so deeply connected to this community,” Braun said. Individual honorees recognized during the evening’s program included Nancy D’Agostino, MDI Health Volunteer of the Year; George Rossi, Birch Bay Village Volunteer of the Year; Marc Woolfolk, Birch Bay Village Employee of the Year; and Beth Applebee, MDI Hospital Employee of the Year. “These honorees represent the very best of who we are,” Maguire said. The program also highlighted new initiatives and honors from the past year. MDI Health launched a free Screening Mammogram Scholarship Program to remove financial barriers to early detection, supported by a generous grant from the Maine Cancer Foundation. An in-hospital food pantry has been opened to meet rising community need and address the link between nutrition and health. MDI Health earned CMS five-star ratings for Patient Experience and Nurse Communication, top marks in the 2026–2027 Lown Institute Hospitals Index, recognition from the American Hospital Association and American Heart Association, and a third consecutive Best Places to Work in Maine designation. The hospital will open its new Main Entrance this fall, as work advances on the expanded Emergency Department and other patient-care spaces. The Building Our Future Campaign has raised more than $56 million in capital and programmatic support to date. “Everything we have accomplished reflects the strength of this community,” Maguire said. “We are grateful to everyone who has contributed their time, talent, leadership, and support to help MDI Health continue meeting the evolving needs of the region.” Subscribe Share Leave a comment
CEO Economic Outlook Index Q3 2026
The Business Roundtable CEO Economic Outlook Index is based on a survey, conducted quarterly since the fourth quarter of 2002, of our member CEOs' plans for hiring and capital spending, and their expectations for sales, over the next six months.
Why frailty and heart health may be more closely connected than we thought
A narrative review proposes cardiovascular frailty as a distinct phenotype that brings together blood pressure regulation, vascular aging, oxi-inflammaging, and clinical frailty deficits. The authors argue that a validated cardiovascular frailty index could support earlier detection and personalized care, although longitudinal studies are needed before the concept can be used clinically.
Health benefits platform Thatch reaches $1B valuation as healthcare costs surge
The five-year-old startup raised $108 million from The General Partnership, Index Ventures, General Catalyst, and Andreessen Horowitz.
Here’s Why Sotera Health Company (SHC) Surges 25% in Q2
Broyhill Asset Management, a Charlotte-based firm, issued its second-quarter 2026 investor letter, which is available for download here. The Broyhill Equity Composite gained 8.8% in Q2, trailing the MSCI All Country World Index’s 15.1% and the MSCI ACWI Value Index’s 10.8%. For the first half, the Composite returned 2.3%, versus 11.5% for the Index. The […]
Is Vanguard Health Care Index Admiral (VHCIX) a Strong Mutual Fund Pick Right Now?
Mutual Fund Report for VHCIX
Should You Invest in the Fidelity MSCI Health Care Index ETF (FHLC)?
Sector ETF report for FHLC
Democrats Gain Midterms Edge as Trump Drags Down Republicans, Per Times/Siena Poll
Even some Republicans are losing faith in Trump’s economy, a New York Times/Siena poll found, and Democrats were favored on the top issues as the sprint to the midterms gets underway.
Max Miller’s challenger launches attack ad based on domestic violence allegations
Democrat Brian Poindexter said that accusations against the Ohio Republican have become “a very prominent topic” in the race.
IMD ranked as Europe’s top business school by Bloomberg Businessweek - IMD business school for management and leadership courses
IMD has reclaimed the top spot in Bloomberg Businessweek’s 2026–2027 ranking of MBAs in Europe and the Middle East, returning to the position it held in 2024. Across the four indexes that make up the ranking, IMD led the region in Learning and Networking, placing third for Entrepreneurship and fifth for Compensation. It is the
NFL fatigue rankings reveal major hidden disadvantage for Texans, 49ers
A new NFL Fatigue Index reveals the massive travel, rest and body-clock disadvantages facing the Texans, 49ers and other contenders in 2026.
NFIB business survey: Main street optimism cools in August
The National Federation of Independent Business’ NFIB Small Business Optimism Index dipped in August to 98.7, just 1.1 points below July’s highest level since August 2025, but remaining above the 52-year average of 98.0. The Uncertainty Index fell 2 points to 89, remaining above the historical average of 68, according to the NFIB monthly report. […]
Most Canadian Small Businesses Haven’t Felt AI’s Impact, Survey Shows
Second-wave findings from Zensurance’s 2026 survey show three-in-five small business owners remain outside the AI conversationTORONTO, Sept. 14, 2026 (GLOBE NEWSWIRE) -- While artificial intelligence dominates the headlines and boardroom discussions, most Canadian small business owners say it has not meaningfully changed the way they operate. New findings from the 2026 Zensurance Small Business Confidence Index show that the frontier technology remains largely in the background for the majority
Marian U. President discusses Crossroads Academic Medical Institute
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FULL SHOW: Inside INdiana Business 9/13/26
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Should Healthcare Rotation Require Action From Oscar Health Stock Investors?
Morningstar recently reported that tougher macro conditions have pushed investors toward healthcare, with the sector index up about 7% quarter to date and Oscar Health participating in that rotation. Oscar Health, a technology focused insurer with strong revenue and earnings per share growth and a wider free cash flow margin, is drawing interest as investors look for defensively positioned healthcare exposure. We will examine how Oscar Health's investment narrative is shaped by investor...
Moderna, 10x Genomics, Oscar Health, and Novavax Shares Are Soaring, What You Need To Know
A number of stocks jumped in the morning session after Morningstar reported that challenging macroeconomic conditions across broader equity markets drove a rotation into healthcare, lifting the sector index by approximately 7% quarter-to-date to reach a 5% valuation premium.
NFIB survey: Small business optimism cools in August from surge in July
The NFIB Small Business Optimism Index dipped in August to 98.7, just 1.1 points below July’s highest level since August 2025.
Ronaldo Book Recommendations: Top 5 Picks
Not every book about Ronaldo covers the same career, and a search for a Ronaldo book can quickly get confusing. Some biographies follow Cristiano Ronaldo from his childhood in Madeira to his time at A...
URI study reveals how waist size and body mass index are associated with mortality in older adults
KINGSTON, R.I. – Sept. 10, 2026 – A longitudinal study led by University of Rhode Island researchers found that waist circumference and body mass index (BMI) provide distinct and complementary information about mortality risk among older adults. Previous studies examining BMI among older adults have produced seemingly conflicting findings regarding mortality risk. This study used […]
NFIB Small Business Optimism Index falls slightly in August
The NFIB released its Small Business Economic Trends report for the month of August 2026, with the report showing a slight dip in Small Business Optimism, down 1.1 points from July 2026 to 98.7. In addition, the report showcased an Uncertainty Index score of 89 points, well above the average of 68 points. This number […]
Why is Lucky Strike Entertainment stock climbing today?
Why is Lucky Strike Entertainment stock climbing today?
Chicago Bulls Receive Poor Rating in Basketball Power Index
The Basketball Power Index (via ESPN) ranks the Chicago Bulls as one of the bottom-five teams in the NBA. Can they beat their poor projection?
Optimism index: Small business owners feel good now, are wary about future
The National Federation of Independent Business released its August small business optimism index on Tuesday and it showed a small dip to a reading of 98.7 from 99.8 in July. But the optimism index remained just above its long-term average …
NC ranks best for business economy, dead last for workers
NC consistently ranks among top U.S. states for business. But a new ranking by Oxfam lists it dead last in this year’s 2026 Best States to Work Index.
How A.I. Tokens Work
As large language models become more advanced, they use ever more resources. Who will foot the bill?
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
LABJ Stock Index: September 7
Cybercriminals Think You’re an Easy Target. Prove Them Wrong No one likes to manage dozens or even hundreds of ever-changing passwords. No surprise, then,
Labor Day 2026: North Carolina ranks best for business economy, dead last for workers
North Carolina is consistently ranked among America’s top states for business. But a new ranking by Oxfam lists the state dead last in this year’s 2026 Best States to Work Index. Oxfam, a global nonpr...
Labor Day 2026: North Carolina ranks best for business economy, dead last for workers
North Carolina is ranked among "America’s Top States for Business.” But a new ranking by Oxfam lists the state dead last in this year's 2026 Best States to Work Index.
LYMA Launches P.O.W.E.R. Index for Wellness Science
LYMA's P.O.W.E.R. Index tackles wellness science-washing with five tests for evidence, outcomes and value. Explore the new framework.
UAE Indoor Entertainment Sector Expands with New Attractions
Explore the rapid expansion of the UAE's indoor entertainment industry, featuring new Harry Potter and Disney attractions, record revenues, and a surge in family entertainment centers.
Georgia football opens 2026 season in record-setting heat
See what the record heat index was for Georgia football's home opener against Tennessee State on Saturday, Sept. 5.
Fernandez Could Be Key To Serious Man City Challenge
Manchester City’s decision to equal the British transfer record of £125m to sign Enzo Fernández feels like far more than the acquisition of another elite footballer. It is a statement about where ...
Gallup Polls Show Democrats Outnumber Republicans Ahead of 2026 Midterm Elections
Data from Gallup shows that Democrats and Democratic-leaning independents have their largest advantage over Republicans since 2008.
Computer Science Tops College Majors by ROI, Study Finds
An Investopedia analysis reveals computer science majors earn nearly $35,000 more annually than typical graduates, achieving the highest ROI at 3,143%. Theology and religion majors have the lowest ROI but lower unemployment. Despite rising graduate unemployment and AI impacts, all majors show positive ROI.
Kelly Loeffler on small business optimism rising, credit card swipe fees
U.S. Small Business Administration Administrator Kelly Loeffler joins Cheryl Casone to discuss the July NFIB small business optimism index rise, credit card swipe fees and the SBA Million Dollar Pitch Competition.
'Soiled' undies and vicious friends research honoured at Ig Nobels
Each year, the Ig Nobel prizes celebrate research that makes you laugh, then makes you think. This year's winners include an "underwear index", a cumbersome kissing definition and why we want friends that will happily stab someone in the eye.
The weather app on your Pixel Watch is adding new watch face modules
Google’s Pixel Weather app is adding three new complications to join the Sunrise and sunset, UV Index, and Weather options.
South African rand muted ahead of business activity PMI
The South African rand was little changed in early trade on Thursday as a weaker dollar offered support, while locally focused investors awaited the latest private-sector purchasing managers' index (PMI) data.
The Medical Minute: Is BMI telling the whole story?
Losing 73 pounds in 15 months is cause for celebration – but according to the body mass index (BMI) calculations, Deborah Dunn would still meet the BMI criteria for obesity. After years of following…
Entertainment Unleashed: Sphere Entertainment’s (SPHR) Innovative Approaches
Sands Capital, an investment management company, released its “Sands Capital Select Growth Fund” Q2 2026 investor letter. The letter can be downloaded here. Select Growth Fund targets U.S. businesses driving significant structural change through disruptive innovation. The fund returned 23.2% in the quarter, outperforming the Russell 1000 Growth Index’s 16.7%. U.S. large-cap growth equities rebounded […]
August Monthly Review: ChatGPT In Epic
Death, taxes, another frontier lab healthcare launch inspiring truly insane LinkedIn takes. As much as I want to stay away, I repeatedly am the crewman unplugging his ears whenever we pass these sirens. So it’s not the first and probably not the last time we dial up the typewriter rather than tie ourselves to the mast. The full blow-by-blow timeline: Health API Guy is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe The End of the Standalone PHR (Jan 8): ChatGPT Health arrives for consumers, at the time powered by b.well. I was bullish on the approach in that the best way for the PHR to finally solve distribution was to meet consumers were they already are (i.e. When Horizontal Meets Healthcare (Jan 9): OpenAI for Healthcare puts out the shingle for enterprises, with SharePoint ingestion standing in for the EHR integration the product actually needed. Another One: Anthropic’s Healthcare Debut (Jan 16): Claude's version, on HealthEx rails instead of b.well, with Agent Skills for FHIR development as the one true vertical-specific investment. ChatGPT for Clinicians: The Trap Sprung (Apr 24): OpenAI filled in the missing GTM middle with a free product for verified clinicians, effectively peeling the enterprise wrapper off ChatGPT for Healthcare and taking the PLG fight directly to OpenEvidence. OpenAI’s Second Attempt at Health (Jul 31): a relaunch of their patient specific app, now branded Health in ChatGPT, where the privacy partition came out, the connectors thinned, and b.well disappeared in favor of first-party FHIR work against a smaller network Beyond a Shingle So what was announced now? Today, we’re introducing a new electronic health record integration that brings authorized patient context from Epic into ChatGPT for Healthcare, along with the Healthcare Public Data plugin for direct, structured access to official healthcare datasets like PubMed, DailyMed, and CMS Coverage. Together, these capabilities bring ChatGPT closer to the systems and sources healthcare teams trust, while supporting the controls and compliance healthcare work requires. The core portfolio is unchanged from prior announcements we delineated and discussed (aside from the relaunch of patient-facing). Since trade publications still seem to be confusing them by using the wrong names: Enterprise sales motion: ChatGPT for Healthcare Protecting their core product / PLG: ChatGPT for Clinicians Consumer/patient-facing product: Health in ChatGPT So really, this is a feature release (specifically for ChatGPT for Healthcare when it comes to EHR integration). What’s cool about it, though, is that we are moving beyond just putting out a shingle. Everything in the January enterprise launch was horizontalizable: Horizontal tech companies thus generally start verticalization with their “putting out a shingle phase”. Telling the world you’re open for business as a horizontal tech company reliably attracts early inbound interest from buyers who are already trying to force-fit horizontal tools into domain-specific workflows and are eager for any signal that the vendor intends to support their use case more directly. Nothing was really vertical specific, which is exactly what you'd expect from the ultimate hypergrowth horizontal company dipping their toes into specific industries. But eventually you have to stop changing the sign on the door and start changing the product. Can you guess where the horizontal product was going to run out of road? This is the core dilemma writ large: verticalization requires differentiation, while scale economics of consumer and horizontal push toward unification. I’ve buried the lede so deep here it will be painful to some readers, but what should be shocking to no one is that my perspective is that EHR integration is the only path that meaningfully resolves this tension for ChatGPT for Healthcare. Integration with Microsoft Sharepoint is fine, but it is categorically insufficient for any product that hopes to influence clinical decision-making. SMART Money Well here we are, eight months later! Real vertical investment has begun, which surprised a few people. One friend in the industry messaged me: “Absolutely no way Epic gave ChatGPT API access.” Looking forensically at the announcements, the integration is notably read-only across appointment notes, laboratory results, medications, and specialist documentation. So while I’m not a betting man, I'd wager the house this is a SMART on FHIR launch: That sounds a lot like USCDI! The recommended path for the workflow they outline would be SMART on FHIR Their Health AI lead’s post is evocative of both standalone and EHR launch SMART, which another termed “ChartGPT” and “EHR Plugin” The implementation burden for SMART on FHIR is the lowest of the available integrative paths This is the team who literally did patient-facing SMART on FHIR with Epic last month Most importantly, if you’re a horizontal company, you generally still haven’t taken the full plunge and thus (overly) value reusability. SMART on FHIR is the logical compromise: healthcare-specific enough to matter, but standardized enough to reuse. Nobody Asked Judy Another friend asked “I thought they had to go to each health system, or did they go direct to Epic and now health systems opt in?” Given the trust paradigms in healthcare, this functionally cannot be Epic hoovering up all the data for OpenAI and shoving ChatGPT in their customers’ faces (or they would revolt). However, I do believe the aforementioned terrible coverage by TechCrunch and other outlets is probably responsible for that question, given the 325 million reference. When using FHIR as a business associate to an Epic customer, there is no EHR gatekeeping to speak of, as that isn’t how fhir.epic.com works: You register an app You pick your APIs You test against the sandbox APIs You list as “Ready for Production” Hospitals pick your app You test and go live with them Bluntly, nobody had to say yes or no in Verona (nor were they given the chance). Vendor Services (their next developer tier up that I doubt OpenAI is using quite yet in this initial release) certainly has contractual paperwork that some resent, but even there, the twin pressures of mounting antitrust and information blocking make outright gatekeeping increasingly fraught. My friend’s sentiment is, to me, representative of a broader industry neurosis, perhaps a sort of scar tissue of prior eras: people assume the gate is still there and never actually try the door. There are certainly other ways Epic (and any EHR) can put its thumb on the scale, but they are not so dumb as to stand in front of a federally mandated API and play bouncer at this exact moment in time. So I think they can and probably should go deeper, as this release is at best parity and at worst behind vertical-specific competition. OpenEvidence did a basic SMART launch with Sutter Health in February, allowing for more convenient evidence search by providers. They then add patient-context (the equivalent SMART on FHIR flow to what we see here) when Cedars-Sinai went enterprise-wide in May. UpToDate has four distinct applications across deeper workflows like patient engagement listed in Epic Showroom and announced a partnership with Epic to power Art at UGM Abridge and other ambient scribes have invested deeply into the deepest bidirectional clinical copilot workflow with integrations well beyond SMART on FHIR. In that light, the “Who is OpenAI primarily targeting here?” is clear. This release brings them into striking distance of OpenEvidence, but not the others quite yet. They are the only one of the three you can reach without building something truly Epic-specific. When will they go further? Competition is a great motivator to overcome the horizontal demons and start building things that can’t be reused: not across industries, not across EHRs, maybe not past the customer you built them for. That’s the price of actually verticalizing. The question is if and when OpenAI will be willing to pay it. Month in Review Here is the monthly review. As a reminder, this is a regular round-up of the month’s posts and other content to surface things you may have missed across regulation, litigation, interoperability, and beyond. AI assistance is used in these bullet summaries so I can focus on articles. Articles Published: None this month Video Content: The Information Exchange: Standards-based Thruple Edition (Aug 14): Back to school for us too, with Brad reporting in from the CMS Health Tech Ecosystem’s one year anniversary in DC. We get into the January CMS-0057 deadline, the fall rulemaking reading list, and why enrollment still keeps most apps off FHIR. The Information Exchange: Epic Dúnadan Edition (Aug 25): A UGM roundup with Ryan Brickner joining for the first time to check our takes against what the building actually thinks. Rangers, Ergo sitting on top of EHI, and a down-market lineup that needs some cuts. Regulatory: Stacked Deck, Bad Hand (Aug 05): ONC’s website refresh took the entire HIT Policy Committee record with it, so I rebuilt the archive and went looking for the regulatory capture story everyone assumes is buried in there. Stacking the deck and winning the hand turn out to be very different things. The Sixth Generation of Patient Access (Aug 19): A quick catalog of the five generations of patient access we’ve layered on since HIPAA, and the two candidates now competing to be the sixth. One is planned. The other is the market routing around the plan entirely. Court cases: Three Cases Walk Into a Docket (Aug 06): Two surprise settlements cleared the board in a single week, and then Judge Maddox dropped ninety-four pages on Vyne v. Henry Schein. The sleeper is a DMCA holding that makes direct-to-database a considerably riskier business model. Epic v. Health Gorilla: Into the MDL (Aug 10): Nine class actions are headed to Miami, and the Panel signaled it wants to bring the case that spawned them along too. That would leave Epic arguing the requests were obviously fraudulent in one courtroom and unknowable in the other. Amazon v. Perplexity: Agents Are Legalized! (Aug 11): The Ninth Circuit vacated the injunction against Comet, holding that the user is the one accessing the servers rather than the company that built the agent. A real win for agentic access, and a much narrower one than the headline suggests. Veeva v. Epic: Come At Me, Bro (Aug 26): Epic’s response brief wants the dismissal affirmed and, unusually, wants the opinion published as precedent. Buried in it is Epic’s own description of what its non-competes actually prohibit, which current and former employees should read closely. EHRs: The Contract Epic Would Never Sign Today (Aug 04): A 1999 SEC exhibit catches Epic licensing nearly its entire product line, Tapestry included, to the company that became TriZetto. The marketing services menu attached to it is the part that will make you blink. Forecast from Verona (Aug 07): The Epic Almanac makes one argument six different ways: the AI is only as good as the networks behind it. Emmie headlines, Art’s context stack is the most ambitious part, and Penny finally gets an autonomous coding date on the calendar. Works With Epic MyChart (Aug 17): Epic’s first new Showroom category since the death of Workshop certifies hardware instead of software, badge on the box and all. Made for iPhone, but for blood pressure cuffs, and rough news for anyone selling the RPM stack sitting in between. UGM Hot Takes 2026 (Aug 20): Everyone else covered the AI announcements, so I went after Savvy deleting the payment gateway, Rangers as Boost with the timer removed, and a down-market lineup with too many entries. Plus the Health Grid tidbits I cannot help myself on. MyChart Central Grows Up (Aug 24): Device data and Emmie turn Epic’s identity hub into a full consumer platform, which is both a logical answer to ChatGPT and a bit of a mistake. It also happens to be the best scraping target Epic has ever shipped. Industry Analysis: The Wrong Yardstick (Aug 12): Vertical software keeps getting judged against Superhuman and Notion, which is the wrong bar entirely. Your user is comparing your product to a whiteboard and forty phone calls before lunch. Primitives vs. Abstractions (Aug 27): Developers want building blocks, systems of record prefer to hand out business logic, and both sides have a real case. There’s no test from the outside that separates the engineering reason from the competitive one, which is why this keeps ending up in court. Cross-industry Comparisons: The Two Kinds of Platform Power (Aug 18): Attention power and record power are different problems that keep getting handed the same regulatory toolkit. Congress’s latest swing at Big Tech shows both what’s possible and where it falls apart. The Dogs of (Platform) War (Aug 21): A CourtListener alert turned up a property management fight with healthcare’s exact shape and none of the Cures Act. Shell prospects, ghost accounts, a notetaker bot that came back to haunt someone, and a lawyer arguing both sides of the same theory in two states. Fractals All the Way Down (Aug 31): Yardi dominates property management right up until you zoom into one segment, where AppFolio owns it outright and Yardi doesn’t appear at all. Where you draw the line around a B2B software market is about to decide an awful lot of cases. Other News: If Judy Had the Courage (Aug 13): A short eulogy for the era when software was allowed to look insane: WinAMP, bold colors, and everything the grey chatbot era has taken from us. External Media: Portland Monthly Health Tech Meetup: Erin O’Brien channeled my own feelings - maybe it’s just because it’s August and beautiful, but the monthly edition of the PDX Health community meetup was a ripper. Make sure to reach out if interested to join for the next one. STAT’s Coverage of Epic This Month: Brittany Trang of STAT did a fantastic job of breaking the FTC investigation that’s been lurking, as well as UGM related coverage, so I had to give her her wish of a meme. Fall Conferences: I’m pumped to be kicking off my fall conference season in NYC at Nabla Accelerate next month, which Chrissy provided the link to apply for. Here’s the rest of my schedule in case you want to meet up: Commonwell (Redwood Shores, CA): Oct 13-14 Open@Epic (Madison, WI): Oct 21-22 eHealthExchange (Austin, TX): Oct 27 Sequoia Project (Austin, TX): Oct 28-29 HLTH (Vegas): Nov 15-18 RSNA (Chicago): Nov 29-Dec 3 Posts I Liked: HTI-6 Should Unbundle API Certification: Josh Mandel makes the case that HTI-6 should split (g)(10) into separate authorization and data certifications, so a PACS or a genomics platform can certify only the role it actually performs. Imaging is the urgent example, but the structure solves a much bigger problem. On implementing ePrior Auth with Epic: Scott Rossignol’s field notes from a live ePrior Auth build on Epic, including the two app registrations nobody warns you about and the CPT mapping problem waiting at the end. CMS-0057 implementations are going to be such a beast. Healthcare point solutions are starting to look a lot like streaming services: Spencer Dorn runs the cable-to-streaming arc against health IT and lands squarely on the bundling half of the cycle. Bundling can be good! It can also be bad! Life is nuanced. Health API Guy is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe
What doctors want patients to know about health wearables
What are wearables? Learn how smartwatches, fitness trackers and smart rings can support health, affect anxiety and help guide talks with your physician.
Creighton Index shows a slight gain in Arkansas business confidence
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Industry-Specific Survey Shows Boost in Small Business Optimism
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Why Alphabet (GOOGL) Is Proving AI Can Strengthen Its Search Business
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Italy business and consumer confidence rise in August
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‘Health Freedom Index’ ranks states by free-market measures not directly related to costs or outcomes. Here are the 20 ‘most free’
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Three things that can speed up the new Spotlight indexing
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VCs Are So Obsessed With This AI Assistant That Its Valuation Jumped Fivefold In Weeks
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Boston Scientific hit by cyberattack causing ‘disruptions’ to parts of its business
This year has seen a growing number of medtechs hit by cyberattacks, and now Boston Scientific has become the latest victim. In an SEC filing posted Aug. 26, the medtech giant said it had detected a “cybersecurity incident” the day before. The incident has affected certain parts of its information technology systems, something that “has resulted in a global disruption to the company’s operations.” The incident has hit not just its information systems but also its business applications, which “support aspects of the Company’s operations,” it said in the filing. This includes its ability to process and ship customer orders. Boston Scientific said it is working to restore the systems, but the timeline remains unknown. Related Baylor Genetics hit by cybersecurity attack targeting patient, staff information As the company investigates the incident, it remains unclear how significantly its business will be affected. “Accordingly, the Company has not yet determined whether the incident is reasonably likely to have a material impact.” The company’s shares were down 3.5% in premarket trading as the news broke. This adds another layer of pressure for the medtech, which last month revealed a new global restructuring program that starts this year and is slated to be completed by 2029. The company said at the time that it “does expect some headcount reductions to result from these restructuring activities,” but did not provide any numbers or specify areas where the cuts may be made. It added, however, that new jobs are also set to be “created in areas of growth.” It was also forced to cut its sales guidance in Q2, saying in late July that it now expects full-year 2026 organic revenue growth of 5% to 6%, down from its previous guidance of 6.5% to 8%. Boston Scientific is one of a growing number of life sciences companies, notably medtechs, that have been hit by cyberattacks this year. These include Abbott, iRhythm, Medtronic and Stryker, as well as Big Pharmas Amgen and Novo Nordisk.
Lenovo Recognized as a World's Top Disability Inclusive Business Reflecting the Global Impact of its Disability Advantage Strategy
Lenovo today announced it has been recognized as a World's Top Disability Inclusive Business through the Disability Index®, the world's leading benchmarking tool for measuring and advancing disability inclusion in business
U.S. consumer confidence slipped to a seven-month low as job and business fears grew
The Conference Board's index dropped to 89.4 as households grew more pessimistic about the labor market and business conditions over the next six months
QXO (QXO) is Rebuilding Business Models for Greater Value
Orbis Investment Management, an investment management company, released its Q2 2026 investor letter for “Orbis Global Equity Strategy”. The letter can be downloaded here. In the first half of 2026, the Global Equity Strategy returned 19.9%, surpassing the MSCI All Country World Index by 7.8%. The market faced narrow breadth in the quarter. The strategy focuses […]
John Fetterman’s Popularity With Republicans Surges, Poll Finds
Pennsylvania Republicans now view John Fetterman, the state’s Democratic senator, more favorably than its sitting G.O.P. senator, a New York Times/Philadelphia Inquirer/Siena poll found.
German business sentiment rises more than expected in August, Ifo survey finds
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A gut microbial health index as a composite biomarker for evaluating overall health
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When Leadership Leads to Wellness: School Health Index (SHI) as a Strategic Tool for Superintendent Decision Making
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German business activity grows in August, PMI shows
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ADF Business Index drives change in corporate America
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AI is moving fast. Health systems need guardrails.
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Google built a camera-based tool to estimate body fat more accurately than wearables
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Report: Small Business Inflation Fears Climb » CBIA
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What 3,600 adults with diabetes revealed about lifestyle and heart health
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Penn State Health, Penn State College of Medicine recognized as best places to work for disability inclusion
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CLA Heartbeat Index Economic Confidence Meets AI Reality Check
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NFIB Small Business Optimism Index rises to highest level since August 2025
Small business optimism increased in July, with the National Federation of Independent Business (NFIB) Small Business Optimism Index rising 2.4 points to 99.8, above its 52-year average of 98.0. The reading marks the highest level since August 2025. Of the index’s 10 components, eight increased and two decreased. Hiring plans improved substantially and contributed the […]
AI Visibility Index: US Media and Entertainment Leaderboard, July 2026
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Researchers Find That Waist Size Is a Powerful Indicator of Health Risks
Measuring waist size may be one of the simplest and most effective ways to detect obesity-related health risks, according to a study by Rutgers Health researchers. The study, published in JAMA Network Open, found that combining body mass index (BMI) with waist circumference, or using waist circumference alone, performed as well as a newly proposed obesity definition that incorporates multiple body measurements.
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How Rep. Max Miller’s Democratic opponent is navigating a ‘surreal’ political opportunity
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This superbug's toll exceeds 3,400. How to protect your loved ones.
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Asia-Pacific parliamentarians urge bolder action for universal health coverage, climate resilience and responsible AI
Parliamentarians representing 16 countries from across the Asia-Pacific region concluded the Ninth Meeting of the Asia-Pacific Parliamentarian Forum on Global Health (APPFGH) today, reaffirming their key role in advancing universal health coverage (UHC) amid the risks and opportunities posed by AI and climate change. In adopting the Phnom Penh Communiqué, parliamentarians urged fellow legislators regionwide to strengthen sustainable financing for UHC to widen access to health for all, including the most vulnerable populations; promote responsible governance of AI amid ethical concerns over this fast-evolving technology; and build climate-resilient health systems to anticipate and respond to mounting pressures ranging from rising sea levels in coastal areas to air pollution and other environmental degradation.The National Assembly of Cambodia, with support from Cambodia’s Ministry of Health and the World Health Organization (WHO), hosted the Forum in Phnom Penh from 11 to 13 August 2026 – the first time the Forum has convened in a Mekong country.Parliamentarians urge action to close gaps in accessIn the Communiqué, parliamentarians recognized that at-risk and marginalized groups are the ones most severely affected by gaps in access to health services. These groups include people living in poverty, women and children, persons with disabilities, older people, migrants, refugees, and those in rural, remote or island communities. The Communiqué urges fellow parliamentarians and policy-makers to advocate for laws and policies that support sustainable financing to protect people from financial hardship, with a focus on primary health care, prevention and equity. "The Communiqué is a call to action. It sets out ambitious, concrete measures that deliver meaningful impact on the ground. We are all accountable for advancing universal health coverage and translating our commitments into tangible results. Cambodia is fully committed to advancing UHC, including the promotion of ‘healthy people, prosperous country’ campaign,” said Samdech Maha Rathsapheathika Thipadei Khuon Sudary, President of the National Assembly of the Kingdom of Cambodia.His Excellency Professor Chheang Ra, Minister of Health of the Kingdom of Cambodia, highlighted the need for collaboration beyond the health sector. “Universal health coverage cannot be achieved by the Ministry of Health alone. It requires support, particularly from parliamentarians, across political, legislative, financial, social protection, education, infrastructure, and environmental domains. While each country follows its own path, one factor is universally critical for success: strong governance and leadership. We all believe in this principle, and in our respective political roles, we remain committed to strengthening these key success factors to ensure that no one is left behind.”Promoting responsible AI adoption Parliamentarians acknowledged that, while AI has already demonstrated its ability to improve access to health services and support delivery, careful and ethical governance is necessary to safeguard quality, safety, privacy and public trust. This underscores the importance of parliamentarians in promoting legal and regulatory frameworks addressing liability, records ownership and data governance, while embracing innovation that protects ethical practice.“Without strong governance, safeguards for privacy and data security, sustainable financing, and attention to those most at risk of exclusion, new technologies may widen existing gaps instead of closing them. This is why parliamentarians matter. We pass laws. We approve budgets. We scrutinize government action. We represent communities. We can ask whether health services are reaching rural, remote, ageing, poor, and marginalized populations. We can ask whether innovation is being guided by equity, evidence, and ethics,” said Hon. Man Hee Lee, President of the Asia-Pacific Parliamentarian Forum on Global Health.Building climate-resilient health systemsParliamentarians also reiterated that the climate crisis is a direct threat to people’s health and to achieving UHC more broadly, deepening the same gaps in access already faced by at-risk and marginalized communities. They recognized the need for WHO Member States to ensure sufficient national appropriations and oversight, and for parliamentarians to raise awareness in their constituencies and mobilize local action in building climate-resilient and sustainable health systems.“Universal health coverage, climate change and AI cannot be addressed in isolation. The same communities struggling to access health services today are often the ones most exposed to climate shocks, and most in need of the opportunities AI can offer if this technology is governed responsibly,” said Dr Saia Ma’u Piukala, WHO Regional Director for the Western Pacific. “Having served previously in this Forum myself as a parliamentarian from Tonga, I recognize how the Phnom Penh Communiqué reflects the shared resolve of legislators across the Asia-Pacific region: the laws parliamentarians pass and the budgets they approve help ensure this progress reaches the people who need it most.”As the Forum drew to a close, delegates reflected on what they would carry back to their own parliaments and constituencies.“I wish to share three points here worth carrying home from Phnom Penh: we need to invest in primary health care as the foundation of coverage; we need to remove the barriers that keep people from care, whether financial, geographic or social; and we need to build systems that are inclusive by design, protecting those most at risk of being left behind,” added Hon. Ouch Borith, First Vice-President of the Senate of the Kingdom of Cambodia.###Notes for editors:The Asia-Pacific Parliamentarian Forum on Global Health (APPFGH) is a platform for parliamentarians to exchange ideas, build political will, strengthen capacity and foster collaboration towards sustainable health action. This was the ninth meeting of the APPFGH, with the theme “Universal Health Coverage in the era of Climate Change and Artificial Intelligence”. Target 3.8 of the Sustainable Development Goals calls on countries to achieve universal health coverage, including financial risk protection, access to quality essential health services, and access to safe, effective, quality and affordable essential medicines and vaccines for all. In the Western Pacific, UHC service coverage index (SDG 3.8.1) rose from 63 in 2000 to 81 in 2023 (figures include Indonesia), and roughly one in four people in the Western Pacific have experienced financial hardship (SDG 3.8.2). Progress towards UHC in the Asia-Pacific region remains uneven, with hundreds of millions of people still lacking access to essential health services or facing financial hardship due to health-related expenses. Strengthening the role of parliaments – through legislation, financing and oversight – is central to closing this gap and accelerating progress towards UHC across the region.Parliamentarians participating in APPFGH in Cambodia this week include: Hon. Pehin Dato Adanan YUSOF, Brunei Darussalam; Hon. Rosmawatty ABDUL MUMIN, Brunei Darussalam; Hon. LORK Kheng, Kingdom of Cambodia; Hon. YOS Phanita, Kingdom of Cambodia; Hon. KHOUN Khundy, Kingdom of Cambodia; Hon. HENG Halim, Kingdom of Cambodia; Hon. KHOENG Noupheap, Kingdom of Cambodia; Hon. SENG Nhak, Kingdom of Cambodia; Hon. LY Sukry, Kingdom of Cambodia; Hon. NHOEURN Raden, Kingdom of Cambodia; Hon. Dr Ratu Atonio LALABALAVU, Republic of Fiji; Hon. Vijay NATH, Republic of Fiji; Hon. Man Hee LEE, Republic of Korea; Hon. Dr Jiho CHA, Republic of Korea; Hon. Jonghun BAEK, Republic of Korea; Hon. Youngsuk SEO, Republic of Korea; Hon. Dr Phayvanh KEOPASEUTH, Lao People’s Democratic Republic; Hon. Suhaizan Bin KAIAT, Malaysia; Hon. Dr Perpetua KONMAN, Federated States of Micronesia; Hon. Ganmaa DAVAASAMBUU, Mongolia; Hon. Charmaine SCOTTY, Republic of Naoero; Hon. Vincent Ambance KUMURA, Papua New Guinea; Hon. Dr Edwin CRUZADO, Republic of the Philippines; Hon. AUUAPAAU Mulipola Aloitafua Mulipola, Samoa; Hon. ASIATA TAVUI Tafu Salevao, Samoa; Hon. Dr Alani Petelo TANGITAU, Tonga; Hon. Paul PAOLO, Republic of Vanuatu; Hon. Franklyn Ezra WILLIAM, Republic of Vanuatu.For more information, contact: WHO Regional Office for the Western Pacific: wprocom@who.int National Assembly of the Kingdom of Cambodia (International Relations Department): ir.nacambodia@gmail.com
Stanford GSB Tops New AI Readiness Index; 42% of Business Schools Require No AI Coursework
A PR firm's new index scores 60 global B-schools on AI readiness and finds none teaches generative engine optimization.
Inflation cooled in July but remained elevated as Fed weighs rate hikes
The Labor Department released the consumer price index (CPI) for July which showed that inflation cooled, even as the pace of price growth remained elevated.
How smoke in the atmosphere impacts your health
Smoke from massive wildfires burning in the Pacific Northwest has reached central Nebraska, pushing air quality index readings higher than normal and prompting health warnings for at-risk residents.
U.S. small business sentiment surged to an 11-month high in July as hiring plans jumped
The optimism index climbed 2.4 points to 99.8, surpassing its 52-year average, while planned hiring jumped to its highest level since October 2022
Democrats Plan New Push to Defeat Max Miller in Ohio After Abuse Accusations
The party’s congressional campaign arm added Mr. Miller’s opponent, Brian Poindexter, to its highly competitive “Red to Blue” list.
Democrats Plan New Push to Defeat Max Miller in Ohio After Abuse Accusations
The party’s congressional campaign arm added Mr. Miller’s opponent, Brian Poindexter, to its highly competitive “Red to Blue” list.
Saber's newest game trailer takes a shot at Gearbox's CEO, if you look closely
The first hint that something might be up with the recent debut trailer for Saber Interactive’s Rideshare Stimulator is an unusual choice of words—aside from that second one in the game’s title. “Don’t take your passengers too seriously,” the trailer’s narrator says, as he describes this upcoming game. It a car game about the gig work of driving eccentric people to their destinations, a riff on Crazy Taxi. And then, he says: “When I think I’ve met the randiest of passengers, someone even stranger gets in.” “Randiest”? That suggests “randy,” which usually means having strong sexual desire. Yet none of the oddball backseat occupants featured in the trailer seem particularly lustful. One is an old man who considers his grandson a failure, another shares the theory that birds might control traffic lights, another says he’s banned from an aquarium. A little later, there’s a license plate, shown 63 seconds into the trailer, on the front of an SUV: USB DRV It’s a Texas plate. The symbol between those letters is a cog wheel. If you know, you know. That’s a reference to Texas-based Borderlands game development studio Gearbox Software (their logo features a cog wheel). More specifically, it’s a reference to Gearbox’s CEO Randy Pitchford, who in 2018 found himself explaining the nature of video he’d saved on a USB drive that was found at a Medieval Times restaurant before being returned to the studio: “It was ‘barely legal’ porn. This girl’s handle was ‘Only 18.’” The “girl” in the video had committed a solo sex act that Pitchford, an avid practitioner of magic, found remarkable. “I realized, this is not a sex worker…This is a fucking magician.” Back then, the USB drive was central to competing lawsuits against Gearbox by the studio’s former lawyer and by Gearbox against him. A settlement in late 2019 “exonerated” Pitchford, per the Hollywood Reporter. The USB story has resurfaced at times, now in a trailer from a company that not long ago was corporate brethren with Gearbox. Saber vs. Gearbox The head of Saber told Game File that the reference is payback. “The dig is because Randy took shots at Embracer in Borderlands 4,” Saber CEO Matt Karch told me when I asked him about the license plate. “Without Embracer, Randy is performing magic tricks at birthday parties for a living.” Having interviewed Karch during a cross-country flight in late 2024, I can confirm that Karch was unimpressed with Pitchford during their time both working in the Embracer group. I’d approached him not out of surprise that there was animosity but that it was manifesting publicly now. Gearbox was founded in 1999, worked on a port of Halo early on, and developed hit series such as the loot-based sci-fi shooter Borderlands before it was purchased by The Embracer Group in early 2021 for $363 million (with a possible earn-out of over $1 billion, if certain targets were hit by 2027). Saber was founded in 2001, worked on a remaster of Halo early on, had a big hit with zombie shooter World War Z and was purchased by Embracer in early 2020 for $150 million, with a potential earn-out of up to $375 million. For a few years, the Embracer group was a voracious acquirer of game studios. Then, as investment dried up, it choked. In March 2024, Embracer sold Saber to an investment company controlled by Saber CEO Matt Karch, and it sold Gearbox in an all-stock deal to long-time Borderlands publisher Take Two Interactive. Other studios were shut down. Hundreds of developers were laid off. Gearbox didn’t say much about their Embracer experience, nothing too direct, at least. In the summer 2024, Pitchford told reporter and occasional Game File contributor Nicole Carpenter that Borderlands 4’s story was in some way thematically connected to Gearbox’s experience at Embracer: “There’s this cultural and emotional shift in me, personally, and at the studio. What does it mean to trade some autonomy for organization?” When Borderlands 4 came out, there was something stranger: the matter of “Embracer’s Bluff,” a location in the game featuring an AI-powered toilet and a large trash dump, according to a detailed Kotaku account of the place. Gearbox never commented on it; Take Two never got back to me about it when I asked them last year. By contrast, since Saber exited Embracer, Karch has been one of Embracer’s biggest defenders, casting their management as well-meaning and supportive despite the layoffs and studio closures that resulted from their excessive expansion. Like others, Saber’s Karch saw Embracer’s as a shot. With Rideshare Stimulator’s trailer, he’s returned fire. “It’s amazing to me how fast people forget those who went above and beyond for them,” Karch told Game File. A rep for Gearbox did not comment by press time. Game File is a reader-supported publication. Your backing makes my reporting—including any coverage of trailer-based beefs—possible. Good news! I’m currently running Game File’s first big sale of 2026. You can get a one-year subscription for 23% off. Click here to take advantage of the limited-time offer. And thank you for your support! Item 2: In brief… 🚫 Wal-Mart has laid off the staff of Restart, a games media outlet launched in 2024, Aftermath reports. 🟥 A GTA VI preview is on the way, at last, via an “extended look” that will premiere, unusually, on Netflix at 3pm ET on August 27, then officially go live elsewhere six hours later. Last week, Game File noted that Take Two label Rockstar Games is overdue for showing off GTA VI, based on the timing of the initial hands-off previews of GTA V and Red Dead Redemption 2. During a call with investors, Take Two CEO Strauss Zelnick said pre-orders for GTA VI were “unprecedented and astonishing,” but added the company can’t predict how many of those pre-orders represent bonus sales vs. sales that otherwise would have been made at launch. During the same call, Zelnick was noticeably bullish on the future of playing games over streaming cloud connections (predicting wider adoption in three or so years). He sounded unbothered by Sony’s plans to stop making discs for new games (he said the business is 90% digital already and predicted that there could still be limited edition physical editions of games “in the same way there’s still vinyl in the recorded music business.”) 👀 Take Two wrote off $43 million in their spring quarter after deciding “not to proceed with further development of an unannounced title in its pipeline from a third-party developer.” 🤔 Some rare age-demographics from a big publisher: Capcom recently told investors that “users in their 20s account for approximately half of the users of both Pragamata and Resident Evil Requiem.” Item 3: The week ahead Tuesday, August 11 Game releases: The Elder Scrolls IV: Oblivion Remastered (Switch 2; already out for PC, PS5, Xbox) continues the Bethesda strategy of putting Elder Scrolls games on everything; Royalty Free-For-All is a Smash Bros.-style fighting game featuring public domain characters such as Mother Goose brawling with Oliver Twist in a stage based on the original Little Shop of Horrors movie. Wednesday, August 12 Game release: Pro Jank Footy (PC, console) is an arcade-style Australian Rules Football game with increasingly ridiculous rules, the more you play (I enjoyed the Steam demo) Thursday, August 13 Game release: Super Mario Sunshine (Switch 2, originally released in 2002 on the GameCube) is released for Switch 2’s Nintendo Switch Online service. This game is the black sheep of 3D Mario games. It’s the successor to the breakthrough Super Mario 64 and the rare Mario game built around a single (vacation resort) theme. Mario’s got a water-spraying backpack, a Yoshi pal and a lot of blue coins to collect.
Tracking Health Security Progress and Building Resilience in Africa
The AHS Index is an objective, evidence-based tool that helps countries and organizations set priorities and identify where investments can have the greatest impact. As health threats become more complex and interconnected, maintaining momentum will require sustained investment, stronger partnerships, and continued political commitment.
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice
AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.
NFIB July Jobs Report: Small business employment index ends four straight months of decline
NFIB said on Aug. 7 that its July Jobs Report shows that the Small Business Employment Index rose after four consecutive months of decline.
HEALTH AND FITNESS: America's fittest cities
The newly released 2026 ACSM American Fitness Index ranks the 100 largest U.S. cities based on the health of their residents and the ways their communities support active living. Commonly called “America’s Fittest Cities,” the annual report looks beyond exercise habits to consider factors such as chronic disease, park access, walkability, recreation facilities, and local policies that make physical activity easier. Beyond the rankings, the report provides guidance for all cities that want to enhance the health and wellbeing of their residents.
Lifestyle medicine helps patients make healthy changes stick
Jefferson Health’s Lifestyle Medicine Program helps patients improve sleep, nutrition, stress and movement through practical goals and team-based support.
FULL SHOW: Inside INdiana Business 8/9/26
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Amid Abuse Claims Against Max Miller, This Democrat Thinks He Can Win His Seat
Brian Poindexter, an ironworker, is in the spotlight in Ohio’s 7th Congressional District, where Mr. Miller faces multiple calls to step aside.
Small Business Employment Index Picks Back Up
NFIB’s July Jobs Report shows that the Small Business Employment Index rose after four consecutive months of decline, registering 102.1 in July after measuring 100.2 in June. The current reading is above the 2025 average of 101.2 and the historical average of 100.0. In July, 36% (seasonally adjusted) of small business owners reported job openings they could
RWJBarnabas Health Named a World's Top Disability Inclusive Business, Advancing Inclusion In Healthcare Workforce
RWJBarnabas Health, the largest, most comprehensive academic health system in New Jersey, has once again been recognized as a World’s Top Disability Inclusive Business based on its performance on the Disability Index®, the leading global benchmark for disability inclusion in business.
RWJBarnabas Health Named a World's Top Disability Inclusive Business, Advancing Inclusion In Healthcare Workforce
RWJBarnabas Health, the largest, most comprehensive academic health system in New Jersey, has once again been recognized as a World’s Top Disability Inclusive Business based on its performance on the Disability Index®, the leading global benchmark for disability inclusion in business.
NFIB July Jobs Report: Small Business Employment Index picks back up
Owners reported more unfilled positions and stronger hiring plans, even as qualified applicants remained scarce and compensation pressures increased.
Business confidence in Mass. rebounds to January 2025 levels
The state's business confidence index rose for a fourth straight month in July, the Associated Industries of Massachusetts said on Wednesday, amid modest expansions in the state and national economies.
South African rand edges up ahead of business activity PMI as risk appetite improves
The South African rand edged up in early trade on Wednesday as a softer dollar and lower oil prices lent support to the risk-sensitive currency, while domestic investors awaited the release of a business conditions purchasing managers' index.
AI and technology investment driving business travel growth
Figures from the GBTA Business Travel Index (BTI) Annual Global Report and Forecast revealed spend is forecast to increase 7.2% in 2026 while the volume of trips will increase 1.3%.