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Yankees’ Max Fried Plan Vs. Padres Comes With Risk
Max Fried is still working himself back to full strength from injury.Because of that, the New York Yankees seem likely to employ a fascinating strategy with him when he takes the mound on Friday against the San Diego Padres.Fried is the scheduled starting pitcher, and that’s not really in question. He should get the ball […] The post Yankees’ Max Fried Plan Vs. Padres Comes With Risk appeared first on HEAVY.
Yankees Have ‘Most Underrated Reliever in the American League’
The New York Yankees are a franchise filled with big names.The legends of yesteryear need no introductions, and neither do many of this season’s superstars. Think guys like Aaron Judge, Gerrit Cole, Max Fried and even Ben Rice. At this point, everyone knows them.That’s not the case for one of the most important pitchers the […] The post Yankees Have ‘Most Underrated Reliever in the American League’ appeared first on HEAVY.
Family-owned Westwood business Sarah Leonard Fine Jewelers closes after nearly 80 years
Sarah Leonard Fine Jewelers, one of the oldest family-owned businesses in Westwood, closed Saturday. Sarah “Sunny” Friedman and Leonard “Lenny” Friedman opened the store, located at 1055 Westwood Blvd., in 1946 under the name Crescent Jewelers.
The curious case of Sam Bankman-Fried's friends' Anthropic shares
Sam Bankman-Fried's Anthropic stake was liquidated in bankruptcy court two years ago. His friends' shares went down a different path.
Red Sox Face Daunting Doubleheader Challenge Against Yankees Aces
After being shut out in consecutive games, the Red Sox must find an offensive answer against Carlos Rodón and returning Yankees ace Max Fried.
Yankees news: Max Fried set to return tonight against Red Sox
Fried expected to start Saturday’s nightcap; Yankees checking in on relievers after Cruz injury.
Yankees Announce Max Fried News Before Red Sox Series
The New York Yankees will get Max Fried back in their series against the Red Sox. MLB.com’s Bryan Hoch reports that Fried will start one of their two games in their doubleheader vs. Boston. Carlos Rodon will start the other game. Max Fried will return for tomorrow’s doubleheader vs. Boston. Aaron Boone said the Yankees […] The post Yankees Announce Max Fried News Before Red Sox Series appeared first on HEAVY.
New York Yankees Announce Max Fried Update During Astros Series
The New York Yankees revealed an update on left-hander Max Fried ahead of Wednesday night's game against the Houston Astros. The post New York Yankees Announce Max Fried Update During Astros Series appeared first on HEAVY.
Red Wings GM Search Gets Several Concrete Names
Elliotte Friedman revealed several names connected to the Red Wings GM search, including Brett Peterson, Jeff Kealty and Jeff Greenberg.
Kushner, Jeffries discuss ways White House and Democrats can collaborate
Kushner, Jeffries discuss ways White House and Democrats can collaborate
Preventative measures to take in navigating postpartum and postpartum psychosis
Yankees Pitching Coach Comments on Max Fried Update
Yankees' pitcher Max Fried threw a bullpen session for the first time since hitting the 15-day injured list. Sparking a comment from pitching coach Matt Blake.
Aaron Boone provides Yankees fans with hopeful Max Fried injury update
Fried is on the IL with a bone bruise in his elbow.
Can Yankees Fans Really Trust the Optimism Around Max Fried?
The Yankees may believe Max Fried’s latest injury is minor, but its fair to question them.
Melody Friedenthal explores new worlds in science fiction book club
Melody Friedenthal, reference librarian at Worcester Public Library, started and coordinates the library's science fiction book club.
Yankees news: Team hopeful that Fried will miss minimal time
How the Yankees can weather the Fried injury; MRIs come back clean on Fried; more Tommy John remembrances.
‘Oppenheimer’ star says he’s stepping back from acting: ‘Frustrated, fed up, fried’
David Krumholtz, prolific character actor from movies like ‘Oppenheimer’ and ‘Supergirl,’ said he’s stepping back from acting: ‘I just removed a humongous burden, one that I truly didn’t fathom the weight of until it was gone.’
Analyst Hands Yankees Positive News on Max Fried Injury
The New York Yankees placed starting pitcher Max Fried on the injured list, which is a bit of a concern, but they got a positive update. The post Analyst Hands Yankees Positive News on Max Fried Injury appeared first on HEAVY.
Yankees Have Clear Internal Option To Replace Max Fried
Fried was placed on the IL and could be lost for the season.
Yankees are 'woefully unprepared' for postseason after Max Fried injury
Fried's injury could come back to bite Yankees GM Brian Cashman.
The locksmith and the conservation scientist
Why well-intentioned but uninformed guessing cannot and will not solve conservation problems, and what we should do instead. Picture this scene: you’re walking down the street, and you see your nei…
Yankees news: Fried to the IL as Rodón returns
Fried hits IL with bone bruise, Rodón steps into rotation; Gomez and Luciano have taken big strides; Tommy John’s lasting impact on the game.
Orthopedic services expand in Duplin County as ECU Health strengthens Kenansville practice
ECU Health says they are expanding orthopedic services in Duplin County with the addition of Dr. Robert Friedman at ECU Health Orthopedics – Kenansville.Friedma
Kalamazoo County Fair returns with new entertainment, 4-H as cornerstone
In 2025, the fair was limited to the Kalamazoo County 4-H Showcase, while the county performed a feasibility study to determine the future of the fair. The result of the study brought investment from Kalamazoo County and a fair with more days, new shows and the classic, fried fair food that visitors love.
Mary Means Business: Restaurant news rampant in Starkville
Restaurant news is rampant in Starkville this week, with food spots ranging from fried chicken and wings to Japanese ramen.
Tommy Sullivan and John Ziegler to Perform at LI Music & Entertainment Hall of Fame on Aug 16th
As part of the Long Island Music and Entertainment Hall of Fame Soundtrack to Summer Series, Musician Tommy Sullivan (a member of the Brooklyn Bridge) will perform LIVE music and Comedian John Ziegler will open with comedy set at the Long Island Music and Entertainment Hall of Fame in Stony Brook Village (97 Main Street, Stony Brook, NY) on Aug. 16th from 3-4pm. The event is free for members or with general admission ticket purchase or $10 at the door concert ticket purchase. For details on this and upcoming events please visit https://www.limusichalloffame.... About Tommy Sullivan A life-long Long Islander and proud U.S. Army veteran, Tommy Sullivan enlisted in 1965 and was accepted to the United States Military Academy Band, where he created the first official rock group at West Point. Reentering civilian life in 1968, he helped create the Rhythm Method, a 7-piece Long Island band which was discovered by Johnny Maestro, then singing lead with the Del-Satins. The combined groups became the Brooklyn Bridge. As band leader and musical director, Tommy penned the group’s horn arrangements on every Bridge hit, including their gold record, Worst that could happen. Upon leaving the Bridge, Tommy co-founded Atlantic Records’ supergroup Ramatam, which was Jimi Hendrix Experience drummer Mitch Mitchell’s first group following Hendrix’ death. For the second Ramatam LP Tommy wrote and orchestrated original material which featured select members of the NY Philharmonic Orchestra. Together with Johnny Maestro, Tommy co-produced Johnny’s final CD, Peace on earth. The critically acclaimed album features Tommy’s arrangements & orchestrations, plus several of his original songs. A Charter Inductee to the LI Music Hall of Fame, Tommy Sullivan continues to write, record, arrange and produce records, serve as musical director/ arranger/conductor for projects across many musical genres plus donates dozens of performances annually for numerous charity events. Tommy Sullivan’s dynamic and unique one-man show, A thousand memories, featuring his vocals and performances on four instruments, has been packing concert auditoriums, nightclubs, private parties–even vineyards-for the past several years. John Zeigler Born and raised in New York, John has performed stand-up comedy for close to 20 years and was the winner of the 2016 "Funniest Comic on the East Coast" Contest at Mohegan Sun. John's opened for such comics as Sebastian Maniscalco, Gilbert Gottfried, Jim Breuer and Robert Klein. He currently headlines clubs across the country and regularly tours with legendary comedian Bobby Collins. John recently released his Dry Bar Comedy Special and Getting My Affairs in Order.
New York Yankees Make Jose Caballero Change During Cubs Series
The New York Yankees got a gem from pitcher Will Warren on Friday night, earning a 2-0 win over the Chicago Cubs in their series opener. On Saturday night, Max Fried will take the mound for New York, while the Cubs will counter with David Peterson. Ahead of first pitch, Yankees manager Aaron Boone made […] The post New York Yankees Make Jose Caballero Change During Cubs Series appeared first on HEAVY.
Chicago Cubs Announce Seiya Suzuki Decision Before Yankees Game
The Chicago Cubs are currently taking on the New York Yankees in an interleague showdown between two of MLB’s most historic franchises. Chicago dropped the first game of its series with the Yankees, and on Saturday, David Peterson (6-7, 5.80 ERA, 77 SO) will get the nod against the Yankees’ starter Max Fried. In the […] The post Chicago Cubs Announce Seiya Suzuki Decision Before Yankees Game appeared first on HEAVY.
My Journey Into Researching Historical Erasure on Public Lands
Most people know me for my work on ocean conservation, Indigenous-led stewardship, and marine protected areas. Over the past year, however, I have found myself increasingly drawn into a different b…
Shohei Ohtani Injury Won’t Effect Deadline Plans, Says Friedman
Los Angeles Dodgers president of baseball operations Andrew Friedman said the Shohei Ohtani's injury won't impact their deadline plans.
Weekly Entertainment Report: Live music and lively arts July 30-Aug. 2 » Nashua Ink Link
"Without music, life would be a mistake." — Friedrich Nietzsche
Agent Business Models May Be Shifting: What I Fear Will Happen
When the new AALA Canon of Ethics goes into effect, authors must be more diligent and sharp in evaluating who they partner with.
New York Yankees news: Max Fried returns, gets start Wednesday
Fried to skip final rehab start; Boone walks back Stanton comments; Domínguez talks trade rumors; Schlittler Cy fave
George Deek’s Story Offers a Rebuttal to Politics of Blame and Hatred
In a sharply argued opinion piece, Felice Friedson […]
Yankees Get Notable Max Fried Update After First Rehab Start
The New York Yankees have spent the last two months watching their team get picked apart by injuries. Max Fried has not pitched in a major league game since May 13. Carlos Rodón has been dealing with left elbow inflammation. Aaron Judge and Giancarlo Stanton remain sidelined on the position player side.The Yankees have stayed […] The post Yankees Get Notable Max Fried Update After First Rehab Start appeared first on HEAVY.
Here's the real reason KFC stopped going by Kentucky Fried Chicken nearly four decades ago
Surrogacy Scandal Upends German Politics
Jens Spahn, a top leader of Chancellor Friedrich Merz’s party, resigned his post after announcing having had a baby by surrogate, which is outlawed in Germany
Why KFC stopped calling itself Kentucky Fried Chicken — and the myths that still won't die
The 1991 name change from Kentucky Fried Chicken to KFC sparked wild myths, but the real reason involved declining earnings and the word "fried."
Yankees news: Aaron Judge not yet cleared for baseball activities
Judge still with some healing yet to do; Lombard ranks highly among prospects; Fried makes rehab start.
Yankees' Max Fried begins minor-league rehab assignment with 3 innings for Triple-A Scranton-Wilkes Barre
How Did Max Fried Do In His First Rehab Start?
The New York Yankees have been without Max Fried since mid-May
Aaron Boone Reveals the Latest on Yankees Star Max Fried
The New York Yankees have been one of baseball’s best teams throughout the 2026 season to date, and as they begin the second half of the season against the Los Angeles Dodgers, optimism continues to grow.With the trade deadline being just under three weeks away, there’s plenty of opportunities for this team to take a […] The post Aaron Boone Reveals the Latest on Yankees Star Max Fried appeared first on HEAVY.
New York Yankees Make Max Fried Announcement Before Dodgers Series
On Friday evening, the New York Yankees will be back in action when they play the Los Angeles Dodgers (at home) in the Bronx.They went into the All-Star break in the middle of a four-game winning streak (after sweeping the Washington Nationals).New York Yankees Make Max Fried AnnouncementMax Fried is in the middle of his […] The post New York Yankees Make Max Fried Announcement Before Dodgers Series appeared first on HEAVY.
A Personal Perspective of U.S.-China Nuclear Science and Security Cooperation
This article by Siegfried S. Hecker presents a historical narrative of U.S.-China cooperation in nuclear security following China’s political opening in the early 1970s.
Cedar Point's Boardwalk Nights returns with entertainment, fun food offerings
Boardwalk Nights returns to Cedar Point July 17 with new entertainment and unique food like fried chicken ice cream.
Iranian newspaper threatens Chancellor Merz
A major Iranian newspaper has published a threat of "retaliation" against German Chancellor Friedrich Merz. Politicians have expressed concern, and the German government has issued a cautious response.
Ryan Friedkin returns to the capital
Ryan Friedkin is ready to steal the show. Roma’s vice president is sending a signal: after about two months, he’s expected at Trigoria tomorrow to unravel all the remaining tangled knots. The Gial...
Politics Unusual: Rep. Kean Jr.'s return to Congress, Sherrill's first 6 months
In this episode of Politics Unusual, FOX 5 NY's Teresa Priolo speaks to The New York Times reporter Tracey Tully about Rep. Tom Kean Jr.'s return to Congress after revealing his struggles with depression. Also, a conversation with POLITICO reporter Matt Friedman.
NC State Health Plan raises premiums, offers new tiered benefits that could help members cut costs
The N.C. State Health Plan's Board of Trustees voted Friday morning to raise premiums for many of its 770,000 members.
Yankees news: Fried tosses successful live BP session
Fried tosses 36 pitches in live BP session; Chisholm taken out of the game with toe injury; Biggest challenge of the year awaits in Tampa; Chivilli returns to MLB
Yankees news: Fried takes next step with live batting practice
Fried to throw batting practice today; four Yankees named All-Stars; Domínguez has biggest shot yet; June Swoon hits as Boone takes some heat; Caballero answers questions on career.
Friedkin give OK for Roma to send official offer for Greenwood
Mason Greenwood is awaiting Roma and the Friedkins’ offer to Marseille. The 2001-born player has put all other options on hold, awaiting a definitive move from the Giallorossi. In the last few hours...
Yankees Reveal Max Fried Injury Update Before Twins Game
The New York Yankees made an injury announcement regarding starting pitcher Max Fried on Saturday.
Around the Empire: Aaron Judge targeting August return
Yankees provide Judge return timetable; Fried throws first sim game; Cruz called up; Jazz clears concussion protocol
Yankees Announce Updates on Giancarlo Stanton, Max Fried
Two of the Yankees' injured stars will be working together in their return to the field.
Some upcoming public talks on shark science and conservation
I will be giving some public talks on shark science and conservation this summer. Here’s how to find me! Tuesday, July 7th, Silver Spring, Maryland (Wheaton Library, 5:30 P.M.) This talk is k…
Rangers Land 37-Goal Star In Blockbuster Trade With Vegas
The New York Rangers have added a new star forward to their roster.According to TSN’s Darren Dreger, the Rangers have acquired forward Pavel Dorofeyev from the Vegas Golden Knights.Sportnet’s Elliotte Friedman later added that the Rangers are sending the 26th pick of the 2026 Entry Draft, the 92nd pick of this year’s draft, and their […] The post Rangers Land 37-Goal Star In Blockbuster Trade With Vegas appeared first on HEAVY.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Judge rejects Biden's attempt to halt release of special counsel inquiry transcripts
U.S. District Judge Dabney Friedrich said in a ruling Friday that the public interest in the material outweighed whatever privacy rights Biden had.
Visitors' viral World Cup videos show what really makes America great
International soccer fans discovering the wonders of America, from spacious skies to chicken fried steak, is giving the U.S. a much-needed morale (and PR) boost.
Yankees news: Cam gets his revenge in Toronto
Schlittler’s fire against Blue Jays; Stanton suffers setback; Fried making progress in rehab.
After closing following a fire 14 months ago, iconic Routt County restaurant is back in business
The new Antlers Café and Bar owner, Chris Braden, is serving up his signature chicken fried steak for customers returning to the historic spot in Yampa following a fire that closed the business for 14...
Florida Democratic Party Chair Nikki Fried ‘disappointed’ in Wasserman Schultz
Fried’s statement follows warnings that Wasserman Schultz’s decision — and the state party’s silence about it — could have ripple effects.
Elliotte Friedman Shares Latest on Oilers' Pursuit of Mike Babcock
NHLPA review complicates Edmonton Oilers' reported Mike Babcock pursuit.
Germany Politics
German Chancellor Friedrich Merz, right, and Vice Chancellor and Finance Minister Lars Klingbeil attend the cabinet meeting at the chancellery in Berlin, Germany, Wednesday, June 10, 2026. (AP Photo/Markus Schreiber)
Sam Bankman-Fried says he 'absolutely' wants a presidential pardon from inside his federal prison cell
Sam Bankman-Fried says he "absolutely" wants a presidential pardon from his federal prison cell, but won't say if his family is lobbying on his behalf.
NC State Health Plan board approves Medicare Advantage plan benefit changes despite retiree concerns
Retirees on the state's Medicare Advantage will face higher out-of-pocket maximums next year, as well as higher copays for many medical services.
NC State Health Plan leaders say WakeMed-Atrium merger could cause premium increases
State Health Plan Executive Administrator Tom Friedman said Atrium charges between 15 and 40 percent more for services. If WakeMed adopts those reimbursement rates, the impact could ripple across hundreds of thousands of employees.
Oceans week 2026
This week is National Oceans week. One of the main events in Washington DC is Capitol Hill Ocean Week (or CHOW). This two-day event, sponsored by the U.S. Government, brought policymakers, scientis…
NC State Health Plan to propose benefit structure aimed at shifting care to 'preferred providers'
The new structure is necessary, plan administrators say, because costs are continue to outpace premiums. Those premiums are likely to increase next year.
Danielle Fishel and Will Friedle open up about 'sad' rift with 'Boy Meets World' costar Ben Savage
Danielle Fishel and Will Friedle are opening up about their falling out with 'Boy Meets World' costar Ben Savage, whom they say declined to cohost their rewatch podcast in 2022, and has since gone silent.
Reds recall Noelvi Marte, option TJ Friedl to AAA Louisville
A major outfield overhaul by the Cincinnati Reds.
Reds recall Marte from Triple-A Louisville, send down Friedl
The Reds recalled Noelvi Marte just days after adding Edwin Arroyo, both from the Triple-A Louisville Bats.
Why ocean science is still one of the worst-funded scientific fields worldwide
For a planet that is 71% ocean, humanity spends a surprisingly small amount of time (and money) trying to understand it. Ocean science sits in a strange place in the research ecosystem. It underpin…
Planetary Health Diet May Lower Obesity Risk at Menopause
The planetary health and low-insulinemic diets — rich in plants and whole grains and low in red and processed meats and fried foods — can aid weight management during menopause, a recent study shows.
Germany Politics
German Chancellor Friedrich Merz attends the cabinet meeting at the chancellery in Berlin, Germany, Wednesday, May 27, 2026. (AP Photo/Markus Schreiber)
Germany Politics
German Chancellor Friedrich Merz attends the cabinet meeting at the chancellery in Berlin, Germany, Wednesday, May 27, 2026. (AP Photo/Markus Schreiber)
Redistricting shuffle: Pia Dandiya shifts candidacy to open CD 22, leaving Brian Mast challenge behind
She enters the new race with an endorsement from Nikki Fried and $1.17M cash on hand.
‘Job’ puts it all on the line
The main reason not to miss the Midwest premiere of Max Wolf Friedlich's “Job” in Writers' intimate Gillian Theatre is the opportunity to see two of Chicago's finest actors close-up
Yankees news: Bombers shuffle rotation, Cole sharp in rehab outing
Yankees shuffle rotation after Fried injury, Cole solid in Triple-A appearance; Jones adjusts to the majors; Schlittler filling the role of ace.
Yankees news: Fried to IL, but worst-case scenario avoided
Fried has bone bruise; Cole makes next rehab start; some thoughts at the quarter-mark
Yankees Lose Max Fried to IL
The New York Yankees will be without their ace starter for a while.
Germany Politics
A girl protests during German Chancellor Friedrich Merz's speech at a discussion with young people during a congress of the German Catholic people the "Deutscher Katholikentag" in Wuerzburg, Germany, Friday,
Germany Politics
German Chancellor Friedrich Merz, second right, attends a discussion with young people during a congress of the German Catholic people the "Deutscher Katholikentag" in Wuerzburg, Germany, Friday, May 15, 2026.
Germany Politics
German Chancellor Friedrich Merz, center, attends a discussion with young people during a congress of the German Catholic people the "Deutscher Katholikentag" in Wuerzburg, Germany, Friday, May 15, 2026. (AP
Germany Politics
German Chancellor Friedrich Merz, center, attends a discussion with young people during a congress of the German Catholic people the "Deutscher Katholikentag" in Wuerzburg, Germany, Friday, May 15, 2026. (AP
'Boy Meets World' star Rider Strong confesses 'shame and fear' of aging: 'I'm letting the world down'
Rider Strong says he's struggled with 'shame and fear' around aging, with his 'Boy Meets World' costars Danielle Fishel and Will Friedle describing the 'body dysmorphia' that Hollywood can breed.
Yankees urged to trade for Giants' 5.18 ERA veteran after Max Fried's elbow injury
New York's depth will be tested.
Sports surgeon discusses Yankees’ Max Fried’s initial elbow diagnosis
Going into Wednesday, Fried had a 2.91 ERA over nine starts, but his walks were slightly up and his strikeouts were slightly down from 2025.
Germany Politics
German Chancellor Friedrich Merz attends for the cabinet meeting at the chancellery in Berlin, Germany, Wednesday, May 13, 2026. (AP Photo/Markus Schreiber)
Germany Politics
German Chancellor Friedrich Merz leads the cabinet meeting at the chancellery in Berlin, Germany, Wednesday, May 13, 2026. (AP Photo/Markus Schreiber)
Napoli block Roma’s talks for Giovanni Manna
Roma continues to work on the search for a new sporting director to succeed Frederic Massara. At the top of the Friedkins’ list is Giovanni Manna, currently director of Napoli, considered the ideal ...
Celtic peaking 'at exactly right time'
Darren O'Dea believes Celtic are peaking at the perfect time as they attempt to reel in Hearts at the top of the Scottish Premiership. Celtic have turned to Martin O'Neill as interim manager twice this season after Brendan Rodgers and Wilfried Nancy left and the veteran Northern Irishman has navigated difficulties both on and off the pitch.
Germany's businesses frustrated by economic decline
No one had higher hopes for Friedrich Merz's chancellorship than the German business community. Meanwhile, however, early euphoria has given way to bitter disappointment.
Germany's business community is frustrated and disillusioned
No one had higher hopes for Friedrich Merz's chancellorship than the German business community. Meanwhile, however, early euphoria has given way to bitter disappointment.
Yankees news: Spencer Jones’ debut
A top prospect gets the call; another setback for Gil; Max Fried’s dominance
Germany learns the cost of provoking Trump
Friedrich Merz’s comments on ‘humiliated’ US have unleashed the president’s wrath
Brewers host the Yankees to start 3-game series
New York Yankees (26-12, first in the AL East) vs. Milwaukee Brewers (19-16, fourth in the NL Central) Milwaukee; Friday, 7:40 p.m. EDT PITCHING PROBABLES: Yankees: Max Fried (4-1, 2.39 ERA, 0.89 WHIP, 43 strikeouts); Brewers: Jacob Misiorowski (2-2, 2.84 ERA, 1.00 WHIP, 59 strikeouts) LINE: Yankees -139, Brewers +117; over/under is 7 runs BOTTOM LINE: The Milwaukee Brewers host the New York Yankees on Friday to open a three-game series. Milwaukee has a 19-16 record overall and a 10-8 record at home.