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3 things to avoid in middle age could mean 13 more years without dementia, study finds
NYU Langone Health research reveals how avoiding high blood pressure, diabetes, and smoking in midlife could add nearly 13 dementia-free years.
Study links better midlife vascular health to nearly 13 more dementia-free years
A long-term study of 12,409 adults found that a greater burden of diabetes, hypertension, and current smoking in midlife was associated with substantially fewer years lived free of dementia. Adults with none of these risk factors had about 30.1 dementia-free years from age 55, compared with 17.5 years among those with all three, a difference of nearly 13 years.
GLP-1s Like Ozempic, Mounjaro May Lower Fracture Risk in Type 2 Diabetes
A new study has found that GLP-1 medications, like Ozempic and Mounjaro, may help reduce the risk of fragility-related fractures in people with type 2 diabetes.
Cutting sweet foods doesn’t curb cravings or improve health
Changing how much sweet-tasting food people eat may not change how much they crave or enjoy sweetness after all. In a six-month trial, researchers found that people assigned to high-, low-, or average-sweetness diets showed no meaningful differences in their preference for sweet foods, body weight, or markers linked to diabetes and heart disease. Many participants also drifted back toward their previous eating habits once the trial ended.
Cutting sweet foods doesn’t curb cravings or improve health
Changing how much sweet-tasting food people eat may not change how much they crave or enjoy sweetness after all. In a six-month trial, researchers found that people assigned to high-, low-, or average-sweetness diets showed no meaningful differences in their preference for sweet foods, body weight, or markers linked to diabetes and heart disease. Many participants also drifted back toward their previous eating habits once the trial ended.
Study finds three midlife health factors that could delay dementia for 13 years
The secret? Having normal blood pressure, no type 2 diabetes, and not smoking between the ages of 45 and 65
Clopidogrel monotherapy bests aspirin when patients with diabetes undergo PCI
After an initial period of DAPT, what's the best next step? A new analysis reviewed data from the SMART-CHOICE 3 clinical trial.
Want To Live Longer? Start Tracking Your VO2 Max
A low VO2 max is considered a stronger predictor of mortality risk than smoking, obesity, high blood pressure, and type 2 diabetes.
Diabetes Drug Used For More Than 60 Years Found to Unexpectedly Affect The Brain
A hidden pathway is emerging.
SGMC Health Earns National Recognition for Excellence in Stroke Care
SGMC Health has earned the American Heart Association's Get With The Guidelines®–Stroke Gold Plus Quality Achievement Award, along with the Target: Stroke Honor Roll and Target: Type 2 Diabetes Honor Roll distinctions.
This smart ring can measure your blood sugar using sweat, no needles required
For the millions of people with type 1 diabetes (and some with type 2 and other forms of the disease) who must monitor their glucose levels, the...
Misfolded insulin may be quietly driving diabetes
Researchers found that insulin-producing cells depend on a team of helper proteins to keep insulin production on track. When one key partner was missing, damaged proteins built up and the cells made less insulin. Strengthening this system could offer a new way to protect the pancreas as diabetes progresses.
Why losing weight may not be enough to prevent type 2 diabetes
A healthy lifestyle can prevent type 2 diabetes for many people, but new research suggests that weight loss alone may not be enough for one particularly vulnerable group. Even after losing about 8% of their body weight and keeping it off for years, people in a high-risk category known as cluster 5 continued to experience rising blood sugar, weakening insulin production, and a strong risk of developing diabetes.
Health Committee advances Collins’ insulin price cap over GOP objections - Live Updates
The bill would limit the private insurance price for the diabetes drug to $35. Its approval by the GOP-led panel was highly unusual.
Cardinal Health to buy Strive Medical, AdaptHealth's diabetes health business for $360M
Cardinal Health is pursuing two tuck-in acquisitions to expand its home care business. | The pharmaceuticals and specialty products distributor plans to buy AdaptHealth's diabetes health business unit and medical supply provider Strive Medical in separate deals worth $360 million.
Regular Coffee Consumption Linked to Health Benefits, AHA Says
A new report from the American Heart Association says that it's safe for most adults to drink up to five cups of coffee per day. New research also suggests regular coffee consumption may be linked to lower risk of stroke, diabetes, and heart failure for some individuals. Health benefits apply to paper filtered or instant coffee.
Coffee may protect your heart but energy drinks could harm it
For most adults, a daily caffeine habit may be safer for the heart than many people assume. A new American Heart Association review found that up to 400 milligrams of caffeine a day, roughly three to five cups of regular black coffee, is generally safe and may even be linked to lower risks of heart disease, stroke, heart failure, and Type 2 diabetes. But the source matters: highly concentrated energy drinks and shots can sharply raise blood pressure and trigger irregular heart rhythms.
Cardinal Health to buy AdaptHealth diabetes unit, Strive Medical for $360 million
Cardinal Health said on Monday it has agreed to buy AdaptHealth's diabetes health business and medical supply provider Strive Medical in separate deals for about $360 million in total, expanding its home care business.
How mental health, environment shape pregnancy sleep
Nearly half of pregnant women in the United States report poor sleep quality, which has been associated with gestational diabetes and high blood pressure during pregnancy. A new study led by researchers ...
Up to 5 cups of coffee per day may potentially lower heart disease risk, doctors say
Drinking up to five cups of coffee a day is safe for most adults, and regular coffee consumption may be linked to a lower risk of stroke, diabetes and heart failure.
Baton Rouge General's Health Tip of the Week: Heat waves may double risk of heart attack
Sponsored by Baton Rouge General When the temperature rises, so does the workload on your heart. Hot weather makes your heart pump harder to cool your body, and dehydration thickens your blood, adding even more strain. That can increase the risk of a heart attack, especially if you have heart disease, high blood pressure, diabetes […]
Challenges and opportunities for diabetes treatment and policy right now
Johns Hopkins experts share insights from their recent research on diabetes management, disease effects, and insulin affordability.
Sugar substitutes are low in calories, but may disrupt your metabolism, study says
Artificial sweeteners also may increase risk of type 2 diabetes and heart disease, the research shows.
Healthy Returns: Employers aren't expanding coverage of GLP-1 obesity drugs – many are finding ways around it
Around 36% of employers said they provide coverage of GLP-1s for both diabetes and weight loss, the same as 2025 and up from 34% in 2024, the survey said.
Men’s average testosterone levels have halved in last 50 years, say scientists
Exclusive: Researchers warn of ‘major crisis in male reproductive health’ partly driven by obesity and diabetes
Church services dull pain, and a new diabetes drug: science stories of the week
From new types of spider hunting techniques to the earliest-known plague victims, here are the most interesting recent scientific developments
Digital diabetes tool shown to improve patient care and cut health care costs
A new study by University of Manchester researchers has linked a digital platform helping people manage type 2 diabetes to better blood sugar control, improved health and potential long-term NHS cost ...
Can GLP-1 medications improve health in people with Type 2 diabetes and PAD?
Research Highlights: GLP-1RA (glucagon-like peptide-1 receptor agonist) medications, which are prescribed to treat Type 2 diabetes and to help with weight loss, were found to reduce the number of deaths, amputations and hospitalizations among people...
Design and Early Implementation Outcomes of a Mobile Health-Enabled Social Support Intervention for Adults Living With HIV and Type 2 Diabetes in Uganda
Background: Adults living with HIV and type 2 diabetes experience complex treatment demands that affect medication-taking, clinic attendance, privacy, social support, and engagement with care. M...
Diabetes patients in Gaza face survival battle amid war shortages
Insulin and equipment shortages in Gaza pose fatal risks, leading to critical health complications.
Glimpsing the Post-Fat Future at the ADA Annual Conference
Over three days at the American Diabetes Association’s annual scientific conference, I glimpsed our post-fat future.
Health fair to provide wellness advice, vaccinations
The Healthways Alliance Community Health Fair 2026 runs from 11 a.m. to 2 a.m. on Saturday and will also feature a special keynote focused on diabetes awareness, education, and healthier living.
One common fat may fuel type 2 diabetes while another helps fight it
Not all fats affect your body the same way. Researchers found that palmitic acid, a saturated fat common in many foods, may contribute to insulin resistance and type 2 diabetes by triggering inflammation, toxic fat buildup, and cellular stress. In contrast, oleic acid—the heart-healthy fat abundant in olive oil—appears to help protect insulin function and may even counter some of the harmful effects of palmitic acid.
Should everyone be on GLP-1s? What science actually tells us (and doesn't) about the broader health benefits
The laundry list of possible health benefits from GLP-1 drugs seems to get longer by the day, from cancer prevention to combating addiction. But while there’s no question these medications show immense promise beyond their use for diabetes and weight loss, science is still catching up.
How Healthy Habits Can Help Prevent Multiple Chronic Diseases
Healthy lifestyle changes lower the risk of multiple chronic diseases by 21% over 20 years in adults with prediabetes, says new JAMA study.
Lance Bass on Having Type 1.5 Diabetes, Being Misdiagnosed, and Taking Control of His Health
In a new interview with Health, the former NSYNC singer opens up about the frustration of incorrectly treating type 2 diabetes for years and how he's currently managing his true diagnosis.
New Rural Health Hub Connects Arkansans to Healthcare Resources, Opportunities
More than 40% of Arkansans live in rural areas, many with insufficient health care due to a lack of transportation, lack of providers, lack of insurance, and a preponderance of chronic conditions such as diabetes or high blood pressure. The University of Arkansas for Medical Sciences (UAMS) understands these barriers…
Fluorescent nanosensor enables rapid, first-of-its-kind detection of key gut health biomarker
Researchers developed an optical nanosensor to rapidly detect a key gut biomarker, enabling faster, accessible screening for conditions such as inflammatory bowel disease, Type 2 diabetes, and liver disease.
Optimize health to combat cardiovascular disease
The threat of heart disease and stroke is growing substantially among women and girls as rates climb for health factors such as high blood pressure, diabetes and obesity, with 6
Why the penis is a barometer of men's health - and we need to wake up to its warnings
Erectile dysfunction can be an early warning of heart attack, stroke, diabetes and dementia.
Medical group leader apologies to Northwestern researcher, others booted from conference over Trump critique
The researchers were distributing an editorial from an American Diabetes Association journal during the group’s annual meeting when they were escorted out by local police and security.
Hiltzik: The Diabetes Association crosses a line
The tally from Trumpian attacks on science now includes billions of dollars in damage to farmers and ranchers and assaults on scientists' freedom of speech.
Baton Rouge General's Health Tip of the Week: How health overconfidence is hurting men
Sponsored by Baton Rouge General A recent poll found that 65% of men believe they’re healthier than other men. Statistically, that can’t be true, but it may explain why so many skip preventive care. The reality is that conditions like high blood pressure, diabetes, heart disease, and some cancers can develop without obvious symptoms. That’s […]
Diabetes drug could slash risk of fatal heart condition in one group, scientists reveal
A diabetes drug called dapagliflozin may help prevent heart failure in people with genetic variants linked to cardiomyopathy, a new study finds.
Police Removed Prominent Scientists from the ADA Meeting. Researchers Respond
The organizers of the American Diabetes Association meeting had a group of researchers removed from the event for sharing an editorial about negative impacts of policy changes to research funding.
Dexcom RCT suggests CGM benefits for broad diabetes population
In this edition of STAT Health Tech: Dexcom's CGM trial, udpates from Apple's annual developers' conference, and wearables.
FDA approves new inhalable insulin treatment for kids with Type 1 diabetes
Genes vs. environment: What really determines your health?
A family history of heart disease, diabetes or high cholesterol can feel like a warning about what’s ahead, but genes are only part of the story.
Genes vs. environment: What really determines your health?
A family history of heart disease, diabetes or high cholesterol can feel like a warning about what’s ahead, but genes are only part of the story.
Once-Weekly Drug Demonstrates Promising Dual Benefits in Obesity and Metabolic Health
/PRNewswire/ -- New data highlight the potential benefits of survodutide, a once-weekly injectable therapy targeting both the glucagon and glucagon-like...
An Avocado a Day May Keep Diabetes, Hypertension, and Obesity at Bay
Research suggests that eating more avocado may help reduce your risk of diabetes, lower blood pressure, and reduce your risk for obesity and other cardiometabolic risk factors.
Infections are major 'health hazard' for people with diabetes
Infections should be considered a "health hazard" in people living with diabetes, with experts warning that current clinical guidelines fail to reflect a substantial but underrecognized burden of illness, ...
Scientists ejected from diabetes conference for distributing journal reprints
Those ousted included ADA journal editor-in-chief Steven Kahn and former ADA president Desmond Schatz...
UW diabetes researcher removed from conference by police
Steven Kahn, director of the UW Diabetes Research Center, was removed by police from a national conference as he and others handed out copies of an editorial.
Diabetes researchers ejected from conference after criticizing White House
The scientists, including the editor of a leading journal, were handing out copies of an editorial criticizing the Trump administration’s handling of biomedical research.
Scientists discover why ozempic may not work for some people
Scientists have identified genetic variants that may make some people less responsive to GLP-1 drugs used to treat Type 2 diabetes. Roughly 10% of the population carries these variants, which appear to cause a mysterious form of "GLP-1 resistance." In several clinical trials, carriers were significantly less likely to reach healthy blood sugar targets while taking GLP-1 medications.
Popular Blood Pressure Meds Linked To Kidney Damage Risk In Type 2 Diabetes
By Dennis Thompson HealthDay ReporterFRIDAY, June 5, 2026 (HealthDay News) — A common class of blood pressure medications might contribute to kidney damage among people with type 2 diabetes, a new study says. Dihydropyridine calcium-channel blockers (DCCBs) work by relaxing blood vessels, and are ...
Medically tailored meals cut costs and health emergencies, study finds
In the US, the first large statewide analysis of Medicaid Massachusetts data reveals that hospital patients with diabetes, heart disease, depression, and other conditions who received home-delivered, dietitian-designed meals experienced significantly fewer health emergencies and lower costs of care than those who did not. At least a dozen US states are rolling out medically tailored meals in pilot projects through the federal-state health insurance program, which serves 71 million citizens who qualify based on income or disability status. Massachusetts is the first to offer this to citizens with diet-related diseases.
Popular GLP-1 weight-loss drugs linked to lower risks of addiction and overdose
A massive study of more than 600,000 U.S. veterans suggests that popular GLP-1 drugs such as semaglutide may do far more than help with diabetes and weight loss—they could also fight addiction itself. Researchers found that people taking these medications were less likely to develop substance use disorders involving alcohol, nicotine, cannabis, cocaine, opioids, and other drugs, while those already struggling with addiction experienced fewer overdoses, hospitalizations, emergency visits, and drug-related deaths.
This new diabetes pill burns fat without the downsides of Ozempic
Scientists have developed an experimental diabetes and obesity pill that works in a completely different way from drugs like Ozempic. Rather than reducing hunger, it activates metabolism in skeletal muscle, helping lower blood sugar and increase fat burning while preserving muscle mass. Early clinical results suggest the treatment is safe and well tolerated.
Metro Health offers free diabetes prevention programs, financial assistance for patients
Omega-3 fish oil shows promise against type 2 diabetes
A new study suggests fish oil may help reduce insulin resistance even in people who aren't obese. In diabetic rats, omega-3 supplementation improved blood sugar levels, cholesterol, and inflammation by shifting immune cells into a more anti-inflammatory mode.
DrPH graduate focuses on digital innovation for diabetes prevention | Harvard T.H. Chan School of Public Health
Qais Dirar, DrPH '26, plans to return home to Saudi Arabia to help lead the regional expansion of a digital health company.
Clean Water, Hospital Construction Among Tribal Health Concerns at Senate Budget Hearing
Health care was the focus of last week’s Senate Indian Affairs Committee budget hearing as lawmakers pressed agency leaders on Indian Health Service funding cuts. While the FY 2027 budget requests $9.1 billion in discretionary funding for the IHS, the budget cuts several key programs, including sanitation facilities, special diabetes programs and scholarships for health […]
Study links eight heart-healthy habits to lower diabetes risk in postmenopausal women
Type 2 diabetes is often associated with excessive sugar intake, but lifestyle factors including body weight, exercise, and smoking habits can also influence risk. A new study published in Diabetology ...
A Discrepancy in Who Gets Diabetes During Pregnancy
One group is an outlier for gestational-diabetes risk, and no one can yet say why.
Scientists discover why Ozempic and Wegovy weight loss eventually plateaus
New NIH research reveals that semaglutide sparks different responses inside appetite-controlling brain cells, offering fresh insight into why GLP-1 weight-loss drugs don’t work the same for everyone. Scientists also found a possible way to extend the drugs’ effects, potentially helping patients push past weight-loss plateaus.
Unpacked: How a tribal health clinic has helped patients find success managing diabetes
A tribal health clinic in Lapwai, Idaho, has helped patients find success managing diabetes and prediabetes. NWPB’s Rachel Sun joined host Connor Henricksen to discuss.
Surprising study finds beef doesn’t worsen blood sugar or diabetes risk
A new clinical trial suggests that eating beef every day may not be as risky for people with prediabetes as many assume. Researchers found that adults who ate 6–7 ounces of beef daily for a month showed no worsening in blood sugar control, insulin function, inflammation, or other key markers linked to type 2 diabetes when compared to people eating poultry instead.
Science for Living: Managing type 2 diabetes in pregnancy
As more people enter pregnancy with type 2 diabetes, researchers and clinicians at UMass Chan are studying new ways to improve care before, during and after pregnancy.
Natural Food Colors Embraced by MAHA Linked to Health Problems
Natural food colors—not just artificial dyes—are associated with an increased risk of Type 2 diabetes and cancer, new research shows..
Study Links Eight Heart-Healthy Habits to Lower Diabetes Risk in Postmenopausal Women
Healthier diet, exercise, and nonsmoking were among habits associated with lower risk of diabetes
Cannabis Linked to Lower Weight And Reduced Diabetes Risk in Mouse Study
But not THC on its own.
Scientists found a smarter Mediterranean diet that slashes diabetes risk by 31%
A large European study revealed that a lower-calorie Mediterranean diet paired with exercise and coaching dramatically reduced the risk of type 2 diabetes. Participants who made these lifestyle changes were 31% less likely to develop the disease over six years. They also lost more weight and trimmed their waistlines compared to those following a standard Mediterranean diet alone.
Guest writer: Kidney disease prevention begins with public health action on diabetes
Whatcom's 'moonshot' is within reach; it begins by making diabetes prevention a public health priority
San Antonio Metro Health, H-E-B relaunch insulin financial assistance program
San Antonio Metropolitan Health District and H-E-B will cover $100 per prescription, including refills, under its relaunched Diabetes Insulin Assistance Program to those who need financial assistance.
City Launches Diabetes Insulin Assistance Program with H-E-B
The San Antonio Metropolitan Health District and H-E-B are relaunching the Diabetes Insulin Assistance Program beginning May 15, 2026, to help residents manage the cost of life-saving diabetes medication.
Who are the Japanese? Huge DNA discovery rewrites history
Scientists analyzing the genomes of thousands of people across Japan discovered evidence for a previously overlooked third ancestral group, challenging the long-accepted “dual origins” theory. The newly identified ancestry appears linked to the ancient Emishi people of northeastern Japan. Researchers also uncovered inherited Neanderthal and Denisovan DNA connected to conditions like diabetes, heart disease, and cancer.
Cannabis compounds may boost metabolic health while supporting weight loss
Researchers identify potential mechanism linked to reduced type 2 diabetes risk
The sugar intake – oral diseases nexus: Leveraging food environments for better population nutrition and health
Across the World Health Organization (WHO) Western Pacific Region, our diets are changing rapidly. Globalization has made processed foods, which often do not align with healthy diets, easier to find, more affordable, and more heavily marketed than ever before. Unfortunately, many of these products are often high in saturated fat, trans-fatty acids, salts and free sugars, contributing to the burden of all forms of malnutrition, including diet-related noncommunicable diseases (NCDs). The impact of these dietary changes is staggering. Sugars, in particular, are empty calories and are often hidden in processed foods and beverages. Over the last 20 years, the health burden linked to sugary drinks has nearly tripled, reaching 52.3 disability-adjusted life years per 100 000 in 2023. Excessive sugar is a leading cause of obesity, diabetes, and—most notably—oral diseases. Today, oral diseases affect over 960 million individuals in the Western Pacific Region. Tooth decay is the most common issue, especially for childre
Greater weight loss from GLP-1 drugs lowers health complication risk
New research to be presented at this year's European Congress on Obesity (ECO 2026, Istanbul, Turkey, 12-15 May) shows that, following treatment for obesity or diabetes or both using incretin-based drugs, losing more weight versus less weight, and losing a little weight versus gaining weight, both lead to relatively lower risk of obesity-related conditions.
Weight loss drug Ozempic linked to lower depression and anxiety risk
GLP-1 drugs like semaglutide—best known for treating diabetes and driving weight loss under the brand names Ozempic and Wegovy—may also deliver a surprising mental health boost. In a massive study tracking nearly 100,000 people over more than a decade, researchers found that these medications were linked to significantly fewer psychiatric hospital visits and sick days.
Apotex Gets Health Canada Approval for Generic Semaglutide
Apotex receives Health Canada approval for generic semaglutide injection, matching all commercial formats of Novo Nordisk's Ozempic for type 2 diabetes treatmen
From brain health to diabetes: 3 reasons to get your vitamin D levels checked
In this study roundup, Medical News Today compiles the latest evidence on the benefits of Vitamin D, focusing on the key findings from 3 studies on diabetes, IBD, Alzheimer's disease.
Your oral microbiome could affect your weight, liver and diabetes risk
An ambitious study has explored how the oral microbiome may affect our metabolic health, raising hopes that conditions like pre-diabetes could one day be screened for via a simple mouth swab
Scientists restore memory by blocking a single Alzheimer’s protein
Researchers have identified a new potential weapon against Alzheimer’s: blocking a protein called PTP1B. In mice, this approach boosted memory and helped brain immune cells clear harmful plaque buildup. Since PTP1B is also linked to diabetes and obesity—both risk factors for Alzheimer’s—it could offer a broader treatment strategy.
Damon Wayans reveals the scary symptom that led to his type 2 diabetes diagnosis
Damon Wayans details his type 2 diabetes journey, the symptoms that alarmed him and his new partnership to raise awareness for the diabetic eye disease DME.
Health Canada approves first generic version of Novo Nordisk's Ozempic
Health Canada has approved the first generic version of Danish drugmaker Novo Nordisk's blockbuster diabetes drug Ozempic made by Indian drugmaker Dr Reddy's Laboratories , its website showed on Tuesday.
Multiple GLP-1 drugs linked to lower AFib risk
The popular drugs, originally developed to treat diabetes, were also associated with an improved survival rate. Benefits were seen in patients who did and did not lose significant weight as a result of treatment.
Health care pops up in San Antonio laundromats
Teams offer quick screenings for blood pressure, diabetes (A1C) and mental health.
Sen. Mark Warner's daughter dies of juvenile diabetes and other health issues at 36
The death of Madison Warner, 36, rendered lawmaker and wife "heartbroken beyond words."
Is stevia actually healthy? What to know when cutting back on sugar
Research has shown diets high in added sugar can be linked to several health issues, including obesity, Type 2 diabetes and fatty liver disease.
U.S. Sen. Mark Warner’s daughter dies after decades-long health battle
The 36-year-old daughter of U.S. Senator Mark Warner has died after experiencing a decades-long battle with juvenile diabetes, the Warner family said Monday.
Blockbuster GLP-1 Diabetes and Weight Loss Drugs Fails in Alzheimer’s Trial
Researchers are exploring whether GLP-1 medications used for diabetes and weight loss could treat Alzheimer’s and addiction.
Six Everyday Habits That Can Help Prevent — And Sometimes Reverse
Advance Community Health is encouraging a shift in how chronic disease is managed, focusing on prevention through six everyday habits like nutrition, movement, sleep, and stress management. Providers say small, consistent lifestyle changes can help patients take control of their health — and in some cases, even improve or reverse conditions like diabetes and high blood pressure
Diabetes patients call for more tailored mental health support
People with diabetes are twice as likely to have depression, a charity backing tailored support says.
After his own diagnosis, New Orleans Broadway star starts foundation for children with Type 1 diabetes
Kyle Banks was diagnosed with Type 1 diabetes during his Broadway tour of Disney's The Lion King after months of struggling with symptoms. Now, the New Orleans native wants to give back to his roots by providing resources for Louisiana children and families living with the disease.
Diabetes testing included in free Healthy Heart Project by Henry Ford Health
It's just a little finger poke, a drop of blood and just like that, you can learn if you're at risk for type 2 diabetes which can be doing slow, subtle damage in your body for years unnoticed.
Why Ozempic doesn’t work for everyone: Scientists just found a hidden reason
A new study reveals that popular diabetes and weight-loss drugs like Ozempic and Wegovy may not work as effectively for about 10% of people due to specific genetic variants. These individuals appear to have a puzzling condition called “GLP-1 resistance,” where their bodies produce higher levels of the hormone targeted by these drugs—but don’t respond to it properly.