SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " cell " 2,277 found 🔀 AI-powered Shuffle
Nominate a Capital Region health care executive who’s making a difference
Who’s running the organizations shaping health care in the Capital Region — and doing it well? That’s the question at the heart of the Outstanding Health Care Executive category in Business Report‘s inaugural Excellence in Health Care Awards. This recognition is for the senior leaders who are making the hard calls, building strong teams and […]
Inaugural Health Care by Food research award honors excellence in food is medicine science
DALLAS, March 23, 2026 — At a time when American dietary patterns are facing renewed attention, the American Heart Association has announced its inaugural Health Care by Food™ Most Impactful Food Is Medicine Research Award, honoring the year’s most...
Inaugural Health Care by Food research award honors excellence in food is medicine science
DALLAS, March 23, 2026 — At a time when American dietary patterns are facing renewed attention, the American Heart Association has announced its inaugural Health Care by Food™ Most Impactful Food Is Medicine Research Award, honoring the year’s most...
Report: iPhone Air is about twice as popular compared to the Plus model it replaced
According to cellular network data from Ookla, the iPhone Air is about twice as popular compared to the iPhone 16...
A promising fatty liver treatment may raise cancer risk
A surprising new study reveals that blocking a supposedly protective enzyme, Caspase-2, could actually backfire—raising the risk of chronic liver damage and cancer over time. Researchers found that without this enzyme, liver cells grow abnormally large and accumulate genetic damage, leading to inflammation, scarring, and eventually tumors, especially with age. While inhibiting Caspase-2 may offer short-term benefits, such as reducing fatty liver disease, the long-term consequences appear dangerous.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Scientists Uncover Hidden “Second Layer” in Human DNA
A newly identified cellular system monitors subtle variations in genetic coding, hinting at a hidden level of control over how genes are expressed.
Top 5 states with the highest number of safest hospitals, according to new report
Healthgrades named 438 hospitals across 40 states for its 2026 Patient Safety Excellence Award, with Texas and Florida among the top-performing states.
New AI tool predicts cancer spread with surprising accuracy
Researchers have discovered that cancer spread isn’t random—it follows a kind of biological “program.” By studying colon tumor cells, they identified gene patterns that signal whether a cancer is likely to metastasize. Their AI model, MangroveGS, can predict this risk with about 80% accuracy and even works across multiple cancer types. This could transform how doctors decide who needs aggressive treatment and who doesn’t.
Scientists turn probiotic bacteria into tumor-hunting cancer killers
Scientists have engineered probiotic bacteria to act as tumor-seeking drug factories. In mice, these bacteria infiltrated tumors and produced a cancer-fighting drug right where it was needed. This targeted approach could make treatments more effective and reduce side effects. More research is needed before it can be tested in people.
Men are losing a key chromosome with age and it may be deadly
Aging men often lose the Y chromosome in a growing number of their cells—and it may be far more dangerous than once believed. This loss has been linked to heart disease, cancer, Alzheimer’s, and shorter lifespans. Researchers suspect Y-less cells may grow faster and disrupt normal body functions. What seemed like a minor genetic quirk could actually be a major driver of age-related disease.
Do Air Fresheners Harm Lung Health?
Dr. Meghan Rebuli is studying the ingredients in air fresheners and their effect on airway cells.
Why people are turning to salt rooms and halotherapy to unwind
Salt rooms regenerate health skin cells and boost our breathing. Here's what to look for when finding a salt room experience.
New dispute emerges around Subnautica 2’s early access release
Lawyers for the ousted—and now partially reinstated—leadership team of Unknown Worlds, the studio behind Subnautica 2, are crying foul over news that the game will be released into early access in May. The release announcement earlier this week was made improperly, potentially “damaging the game and sowing additional confusion among the Subnautica community,” the lawyers said in a letter sent on Tuesday to Vice Chancellor Lori Will of Delaware’s Court of Chancery. In their letter, the lawyers also floated the idea of asking Will to find Krafton in contempt of the court’s ruling. The letter was sent just one day after Will’s bombshell ruling that publisher Krafton had breached its contract with Unknown Worlds’ executive team, when it fired them last June. The new issue isn’t necessarily the May early access timeframe, but how the news was announced. The letter and Krafton’s response have not been previously reported. A quick recap of prior events: Subnautica 2 is an unreleased, underwater survival adventure and the most-wishlisted game on Steam. Last year, longtime Unknown Worlds CEO Ted Gill, along with studio co-founders Charlie Cleveland and Max McGuire, were fired by Krafton. They swiftly sued, saying the publisher had terminated them to avoid paying out up to $250 million in potential performance-based bonuses. The studio leaders had hoped to earn that with an early access release of the game, which Krafton had blocked. The publisher argued in court that Subnautica 2 wasn’t ready, which the ousted execs disputed. On Monday, Will ruled that Krafton had violated its contract, firing the execs to avoid the performance payouts, and that it had to reinstate Gill and give him full authority over any early access release for Subnautica 2. On Tuesday, IGN reported on a new memo issued that day to Unknown Worlds staff by Steve Papoutsis, the executive Krafton had put in charge of Unknown Worlds after the 2025 firings. In the note, Papoutsis said that Subnautica 2 had passed a key development milestone “last week” and that he and Krafton had determined the game “is ready for Early Access release in May.” This news appeared to catch the lawyers for Gill, Cleveland and McGuire by surprise. On Tuesday night, they sent a letter to Will expressing “serious concerns” about whether it would be possible to forge an agreement with Krafton consistent with the judge’s order. Papoutsis’ memo was a problem, they wrote. He didn’t have the authority to declare anything about Subnautica 2’s release. As of 9am ET on Monday, March 16, the effective date of Will’s order, Papoutsis wasn’t CEO of Unknown Worlds. Gill was. And, per Will’s order, only Gill could make Subnautica 2 release decisions. They continued: Krafton self-servingly announced the launch without any regard to its impact on the game, the team, or the community—let alone this Court’s Opinion. Announcing the release of a game is momentous, and it is typically accompanied by significant marketing activity, fanfare, and community coordination. And most importantly, the announcement is carefully designed to maximize excitement for the game. That entire process was supposed to be driven by Mr. Gill. However, in defiance of the Court’s Opinion, Krafton has now taken that away, further damaging the game and sowing additional confusion among the Subnautica community. The lawyers speculated that Krafton had “intentionally leaked” Papoutsis’ memo and then issued an official statement to confirm the leak. Game File is a reader-supported publication. My reporting is only possible through support from readers like you. To support my work, consider becoming a free or paid subscriber. Subscribe On Wednesday, lawyers for Krafton defended their client in their own letter to vice chancellor Will, saying nothing they did violated her order nor showed contempt: Papoutsis’s message was simply celebrating the UW employees’ efforts toward a past event: Krafton’s pre-Opinion determination that Subnautica 2 was ready for Early Access release. There was nothing improper about conveying the results of the milestone review or thanking the development team for their dedication and talent. They added that Gill could still make his own call about Subnautica 2’s release: In his role as CEO, Gill will be able to assess independently his views on the state of Subnautica 2 and the appropriate release schedule; nothing in Papoutsis’s message alters Gill’s authority or discretion. Vice chancellor Will has not responded to the letters and doesn’t necessarily have to. Both parties were previously ordered by Will to confer this week and submit a proposed judgment consistent with her ruling. The letter from Gill’s attorney’s this week doesn’t indicate whether he would or would not support a May release for Subnautica 2. But it could limit his options. And, if Gill’s lawyers are right, the lack of marketing fanfare around the leak of the May date could dull the launch of the game. Any harm to Subnautica 2’s launch is an extra sensitive issue given the context of the legal dispute: millions of dollars of payouts are on the line, tethered to the scale of the game’s initial performance. In her ruling on Monday, Will noted that there was obvious “bad blood” between Gill’s side and Krafton but that the two would need to work together: “They can—and must—act in good faith to navigate their remaining contractual relationship.” Item 2: A new kind of couch co-op game A highlight of GDC each year is the Alt.Ctrl showcase that features games played with extremely experimental controllers. Perusing this year’s offerings last Friday, I found a game controlled with giant scissors, another with big toothbrushes and one that amounted to dumpster diving. My favorite was Pivot, a co-op game about collectively maneuvering a couch. It was developed by students at the University of Utah’s masters of arts and engineering games program. Players lift and tilt the physical couch in order to control the position of a virtual one. That virtual one is moving through an obstacle course on-screen, while being pursued by a giant skull. Developer Nishant Verma told me at GDC that the couch is made of styrofoam (this became more evident as I watched!) and that the name was a riff on an episode of the sitcom Friends. Item 3: In brief… 🚫 Ubisoft is laying off more than 100 workers at its Red Storm studio, as the North Carolina location known for decades for its Tom Clancy games, ceases in-house game development, VGC reports. 👀 On Monday, Nvidia’s revealed its DLSS 5 AI-driven graphics technology that purports to improve game graphics… and it has been roasted about it by the media and the online gaming public for the remainder of the week. The tech changed the faces of characters in footage from Resident Evil Requiem, Hogwarts Legacy and EA Sports FC, drawing accusations of giving carefully art-directed games the generic look of AI “slop.” Nvidia CEO Jensen Huang had said on Monday that “DLSS 5 is the GPT moment for graphics—blending handcrafted rendering with generative AI to deliver a dramatic leap in visual realism while preserving the control artists need for creative expression.” By mid-week, Huang was telling Tom’s Hardware that the new tech’s critics were “completely wrong” because game-makers could still “fine-tune the generative AI” to suit their game’s aesthetics.
What Business Leaders Can Learn From A Symphony Orchestra
How Montreal Symphony Orchestra leaders balance artistic excellence and business strategy, offering lessons in leadership, innovation and audience growth.
Pikl Pioneers a New Category of Insurance-Enabled Business Models, Earning it 20% UK Short-Term Rental Market Share
Pikl, the company pioneering insurance-enabled business models that drive revenue whilst protecting against downside risk, today announced that it has achieved 20% market share in the UK short-term rental market – the first industry in which its insurance-enabled growth solutions have been delivered. The achievement comes just two years after Pikl launched its flagship flexible cancellation solution in 2024, which allows property management companies (PMCs) to offer guests the flexible booking o
Exclusive: $599 MacBook Neo easily beats $1,119 Dell laptop on Windows 11 benchmarks - yes, macOS may well be the best platform ever for Microsoft's OS
Despite running a mobile CPU and Windows in a virtual machine, the MacBook laptop excelled in single-core CPU performance
VT Markets and Newcastle United Clinch Double Wins at Forex Sports Awards 2026
VT Markets, a leading global multi-asset broker, has been honoured with the prestigious "Best Global Football Sponsor - Newcastle United F.C" and "Best Commercial Spot - Together, Into Tomorrow" awards at the Forex Sports Awards 2026. The double accolades recognises the brand's high-impact partnership with Newcastle United, celebrating excellence in global brand alignment and fan engagement.
Washington Spirit Named Finalist for Sports Business Journal’s 2026 Sports Team of the Year
Washington, D.C. (03/17/2025) – The Washington Spirit has been named one of seven finalists for Sports Business Journal’s 2026 Sports Team of the Year Award, marking the first time the organization has been a nominee for the illustrious annual award. Sports Team of the Year honors a best-in-class organization that demonstrates excellence, influence, innovation and creativity in the business practices of operating a sports franchise across all […]
Washington Spirit Named Finalist for Sports Business Journal’s 2026 Sports Team of the Year
Washington, D.C. (03/17/2025) – The Washington Spirit has been named one of seven finalists for Sports Business Journal’s 2026 Sports Team of the Year Award, marking the first time the organization has been a nominee for the illustrious annual award. Sports Team of the Year honors a best-in-class organization that demonstrates excellence, influence, innovation and creativity in the business practices of operating a sports franchise across all […]
Kennedy Center votes to shut down operations for 2 years and names a new president
The widely expected decision comes in the wake of numerous resignations and cancellations during President Donald Trump's second term, although Trump himself has cited the need for repairs as a reason for the closure.
Cue Biopharma Reports Fourth Quarter and Full Year 2025 Financial Results and Business Highlights
Advanced research and development of CUE-401 for IND (Investigational New Drug) readiness –CUE-401 is the Company’s lead asset for the treatment of autoimmune and inflammatory diseasesAppointed industry veteran Lucinda Warren as Chief Financial and Business OfficerRaised net proceeds of $10.2M through an underwritten public offeringAnnounced strategic collaboration and license agreement with ImmunoScape to develop breakthrough cell therapy approach for solid tumors – Entitled to receive upfront
Scientists build tiny hydrogel machines that mimic living cells
Hydrogel micromachines recreate the push and pull of living cells, helping scientists study how mechanical forces shape tissues in the lab.
NYC Health + Hospitals/Kings County Adult Intensive Care Units Earn National Beacon Awards for Excellence - NYC Health + Hospitals
NYC Health + Hospitals/Kings County today announced that two of its adult critical care units have been nationally recognized by the American Association
Are Cellphones Harmful to My Health?
For older adults, excessive smartphone time can fuel anxiety, isolation and even physical pain
Apple quietly launches AirPods Max 2
The successor to its premium headphones cost $549 and are launching with enhanced active noise cancellation, the H2 chip, live translation, better sound quality, and more.
Apple Announces AirPods Max 2
Apple today unveiled AirPods Max 2, with key upgrades including the H2 chip, increased active noise cancellation, improved sound quality, and features such as Adaptive Audio, Conversation Awareness, Voice Isolation, and Live Translation. AirPods Max 2 have the same overall design as the original AirPods Max, with most of the new features coming from the upgrade to the H2 chip.
More than 1,800 US flights canceled as massive March storm disrupts travel
A massive storm sweeping the US forced more than 1,800 flight cancellations, disrupting major airline hubs during the busy spring break travel season.
Cells can sense 10x farther than expected and it may explain cancer spread
Scientists have discovered that cells can sense far beyond the surfaces they touch. While individual cancer cells can probe about 10 microns ahead by tugging on surrounding collagen fibers, clusters of normal epithelial cells can combine forces to detect layers as far as 100 microns away. This long-range “depth sensing” helps cells decide where to migrate. Understanding how it works could reveal new targets to stop cancer from spreading.
Is stem cell therapy the next frontier to treat diabetes? Louisiana experts aren't convinced.
Personalized therapies for diabetes, while showing promise in international studies, is met with healthy skepticism from Louisiana experts. "Maybe in 20 years," a doctor at LSU Health says. Here's what to know now.
New Data Centers Will Be Powered by Human Brain Cells
Cortical Labs announced that it's working on "biological data centers" in Melbourne, Australia, and Singapore.
NBCUniversal cancels multiple talk shows, longtime entertainment news program
The cancellations are expected to result in layoffs for the shows’ crews and executives within the NBCU first-run division.
Textbooks were wrong: Scientists reveal the surprising way human hair really grows
Hair may grow in a completely different way than scientists once believed. Instead of being pushed out from the root, new research shows that moving cells inside the follicle actually pull the hair upward like a microscopic motor. Advanced 3D imaging revealed a spiral movement of cells that generates this force. The finding could change how scientists study hair loss and design future treatments.
NHS and MoD will be urged to buy British tech to drive growth amid Iran crisis
Treasury minister Spencer Livermore trails new strategy as chancellor pins hopes on benefits of AI amid global uncertainty
Every Single Cell in the Universe Is Conscious, Research Suggests
This could reshape everything we know about cognition.
Centennial Students Earn 3rd Place at Iowa Regional Science Bowl
Michael Stevens, Ian Anderson, Anna Bruns, Jared Bond, Alice Baghdasaryan and teacher Madison Greif. (Not pictured: Team Manager Vivian Zhang.) Congratulations to our outstanding team for earning 3rd place at the 2026 Iowa Regional High School Science Bowl, held on the campus of Iowa State University on March 7! We’re proud of these students for representing our school with excellence in this challenging academic competition that tests knowledge in science, mathematics, and teamwork.
Reeves vows to ‘crack down’ on energy and fuel bosses exploiting Britons through ‘rip-off’ prices
The chancellor is set to meet with energy bosses over concerns that companies are profiteering from oil and gas prices
James Blake: Trying Times review – platitudes about politics and Kanye can’t detract from an excellent album
Amid the stylistic shifts of Blake’s seventh record come samples of Dusty Springfield and Dizzee Rascal: gripping distractions from some preachy sentiments
Three Baystate Health Hospitals Achieve 2026 Healthgrades Patient Safety Excellence Award
Baystate Health is pleased to announce that Baystate Franklin Medical Center, Baystate Noble Hospital, and Baystate Wing Hospital have achieved the 2026 Patient Safety Excellence Award™ from Healthgrades, the #1 site Americans use to find a doctor or hospital.
Scientists find a new therapeutic target present on up to half of all tumors
For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth ...
10 projects from Newsom's mental health bond were supposed to open in 2025. That didn't happen
Projects supposed to offer mental health and substance use care to foster youth, new mothers, unhoused people and others have been delayed or cancelled.
Century Therapeutics Reports Full Year 2025 Financial Results and Business Updates
CNTY-813, lead beta islet cell therapy program as a potential functional cure for type 1 diabetes, in Investigational New Drug (IND)-enabling studies; IND submission expected in 4Q 2026 to support anticipated initial clinical data in 2H 2027CNTY-308, a CD19-targeted CAR-iT cell therapy engineered with Allo-Evasion™ 5.0, on track to enter the clinic in 2026Strengthened balance sheet and cash runway extended into 1Q 2029 from oversubscribed $135 million private placement in January 2026 PHILADELPH
Depression may start with an energy problem in brain cells
Researchers have discovered a surprising change in how cells produce energy in people with depression. Brain and blood cells in young adults with major depressive disorder produced more energy molecules at rest but had trouble increasing energy production when needed. Scientists believe this imbalance may contribute to symptoms such as fatigue and low motivation. The finding could help pave the way for earlier diagnosis and more personalized treatments.
Minority- and Women-Owned Businesses Sue Texas Comptroller over Contracting Program’s Conversion + Cancellation
Takeaways
One possible recipe for life on Titan is a bust
An experiment mimicking conditions on the Saturn moon suggests that cell-like bubbles don’t form in methane lakes, puncturing hopes for alien life.
Adam Scherr, FKA Braun Strowman in WWE, Launches Production Company
Meat Castle Media will be run by the 'Everything on the Menu' host and his producing partner Nick Antonicelli, in partnership with the 'Beachfront Bargain Hunt' studio.
NYC Health + Hospitals/Elmhurst Celebrates Critical Care Teams' AACN Silver Beacon and DAISY Awards for Nursing Excellence - NYC Health + Hospitals
NYC Health + Hospitals/Elmhurst today announced it received two distinguished national recognitions honoring its Critical Care and Medical Intensive Care
Report: Scott County Jail staff ignored inmate’s mental health crisis
Scott County Jail workers allowed a woman in mental distress to repeatedly bang her head against cell walls without intervening, a report alleges.
How to Solve One of the Most Expensive Problems in Employer Healthcare
A small share of employees drives a disproportionate share of employer health-care spending: They are patients whose complex conditions go undiagnosed as they cycle through a fragmented care system. A diagnostic-focused “center of excellence” model—such as the Mayo Clinic Complex Care Program—offers a different approach: coordinated, multidisciplinary evaluations that identify the right diagnosis quickly. Evidence from employer claims shows that earlier, accurate diagnoses can improve outcomes, reduce unnecessary procedures, and lower costs by shifting care from repeated testing toward targeted treatment.
Minnesota businesses hit by now-cancelled tariffs are lining up for refunds
The Supreme Court ruled President Donald Trump’s tariffs illegal, but did not get into any process for making up lost revenue to businesses
US is 'on top' of possible Iran sleeper cells, Trump says. What are they?
Asked about domestic Iran-aligned sleeper cells, Trump said the United States is "watching every single one of them." What to know.
Scientists discover molecule that stops aggressive breast cancer in its tracks
Scientists at Oregon Health & Science University have developed a new molecule that could open the door to treating triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of the disease. The compound, called SU212, targets and disables a key enzyme that cancer cells rely on to fuel their growth. In tests using humanized mouse models, the molecule caused tumors to shrink and slowed the spread of cancer by forcing the enzyme to break down.
Reeves to face MPs’ grilling over cost-of-living pressures
Chancellor to take Treasury questions amid market turbulence linked to Middle East conflict
Germany's Iran Policy in the Dilemma of International Law and Israeli Interests
When it comes to the Middle East, Germany appears to be pursuing a policy that completely disregards the rules of international law.
Human Brain Cells Run New Data Centers in Singapore, Melbourne
Biotech startup Cortical Labs is working on two small data centers run by human brain cells, putting lab-grown neurons onto silicon in an experiment that could one day challenge chips from the likes of Nvidia Corp.
Stanford Scientists Uncover the Molecular Mistake That May Trigger Brain Aging
Scientists have identified a critical breakdown in the cellular machinery that produces proteins in aging brains.
Samsung’s Mammoth 20,000mAh Silicon-Carbon (Si/C) Smartphone Battery Fails At 960 Cycles
Samsung's experimentation with mammoth silicon-carbon (Si/C) battery cells continues even as the 20,000mAh cell proved to be dead end.
Multivitamins may slow biological aging in older adults, study finds
The research focused on biological aging, which reflects wear and tear on the body at the cellular level.
Lee Health: Excellence in nursing, excellence for our community
If you follow Lee Health on social media, you’ve likely seen the news, but I wanted to take a moment to personally celebrate ...
Commanders should target Colts' defender to improve secondary
One free agent with local ties could be an excellent signing for the Commanders.
US science budgets have been spared. So why is no one celebrating?
The Trump administration’s proposals to eviscerate the NIH and NSF have been overturned in Congress after a year of cancelled programmes and legal wrangling. Yet as funding continues only to dribble out of downsized and politicised agencies, few believe that US science is out of the woods yet
We’ve found your next must-see crime drama, as ITV’s Gone tackles a gripping case inspired by real events
Eve Myles and David Morrissey are on excellent form in ITV's new psychological thriller that uses elements of a real case
The Wolf of Call Street: New College of Business elevates campus
The new Herbert Wertheim Center for Business Excellence both takes students out of their typical routine and encourages them to strive for success.
Scientists discover a brain signal that may trigger autism’s domino effect
Researchers have uncovered a surprising molecular chain reaction in the brain that may play a role in some forms of autism. The study suggests that nitric oxide, a tiny signaling molecule normally involved in fine-tuning communication between brain cells, can sometimes trigger a cascade of changes inside neurons. When nitric oxide activity rises, it can alter a protective protein called TSC2, weakening an important cellular brake and allowing the mTOR pathway, which controls growth and protein production, to become overactive.
Scientists create cartilage scaffold that helps the body regrow bone
Researchers in Sweden have engineered a cell-free cartilage scaffold that can guide the body to rebuild damaged bone. By removing the cells but preserving the structure and natural growth signals, the material acts as a blueprint for the body’s own repair process. In animal studies, it helped regenerate bone without triggering strong immune reactions. The team now plans to scale up production and begin testing the approach in humans.
NYC Health + Hospitals/South Brooklyn Health's Medical and Surgical Intensive Care Units Recognized with Silver Beacon Awards for Excellence - NYC Health + Hospitals
NYC Health + Hospitals/South Brooklyn Health today announced that their Medical Intensive Care Unit (MICU) and Surgical Intensive Care Unit (SICU) both
Secretary Kennedy says cell phone-free schools is how America becomes healthy again
HHSSecretary Robert F. Kennedy Jr. said during an episode of The Joe Rogan Experience that cell phone-free schools will help make America healthy again.
Keanu Reeves\' band to perform in Hershey this summer
You may know Keanu Reeves for his performances on the big screen, playing lead roles in films like "Bill & Ted's Excellent Adventure," "The Matrix" and "John Wick."
Scientists Cut Amyloid Plaques by 50% in Mice With Engineered Cells
"This study marks the first successful attempt."
What are Fatty15 healthy aging gummies, and do they actually work?
Fatty15 launches Healthy Aging Gummies with pure C15:0 for cellular health support. Here’s what makes them unique and how to shop the new supplement.
Huskies Dispatch Fading Trojans
The Washington Huskies have made a habit this year of coming up short against good opponents due to limited offensive options. Zoom Diallo and Hannes Steinbach have been excellent, but haven’t received enough support from the rest of the roster. On Wednesday night, Diallo and Steinbach were so good that they didn’t need much support. […]
Scientists discover the protein that malaria parasites can’t live without
Scientists have uncovered a crucial weakness in the malaria parasite that could open the door to new treatments. Researchers identified a protein called Aurora-related kinase 1 (ARK1) that acts like a traffic controller during the parasite’s unusual cell division process, ensuring its genetic material is properly separated as it multiplies. When scientists switched off ARK1 in laboratory experiments, the parasite could no longer replicate correctly and failed to complete its life cycle in both humans and mosquitoes—effectively halting its ability to spread.
Becker’s Hospital Review Names RWJBarnabas Health to 2025 “100 Hospitals and Health Systems with Great Heart Programs" List
RWJBarnabas Health has been named to Becker’s Hospital Review’s 100 hospitals and health systems with great heart programs for the third consecutive year in 2025. The hospitals, health systems and institutes recognized on this list are distinguished for their excellence in heart and vascular care.
Pressure points: Balancing clinical and financial priorities in health care | Harvard T.H. Chan School of Public Health
As financial pressures intensify across health care, leaders face difficult choices that test their ability to protect clinical excellence while sustaining their organizations. Join leading experts for a candid conversation about navigating the tensions between clinical and financial priorities—and the skills, strategies, and innovations needed to lead effectively through these competing demands.
Your Cells Can ‘Remember’—Meaning Your Entire Body Could Be Conscious, Some Researchers Suggest
A recent study suggests that memories aren’t just stored in the brain, raising important questions about cognition.
WSU celebrates 65 years of nuclear excellence
A major expansion currently underway will support the university's continuing commitment to research, training and America's energy future.
What Your Phone Knows Could Help Scientists Understand Your Health
Stanford scientists have released an open-source platform that lets health researchers study the “screenome” – the digital traces of our daily lives – while protecting participants’ privacy.
A History of HeLa Cells: How the Immortal Cells Advanced Biomedical Science
HeLa cells are the most famous human cells in science. Discover how cervical cancer, HPV proteins, and bioethics shaped one of medicine’s biggest breakthroughs.
First M4 iPad Air Benchmarks Surface
Ahead of the launch of new iPad Air models equipped with the M4 chip, preliminary Geekbench benchmark results have surfaced for the device, giving us an idea of how its performance compares to the prior-generation M3 iPad Air. A pair of benchmarks from the 13-inch M4 iPad Air with Wi-Fi + Cellular (iPad16,11) suggest the M4 iPad Air CPU is 17.3 percent faster in single-core performance and 7.9 percent faster in multi-core performance.
What does Syracuse’s new chancellor mean for SU sports? ‘We need to have top-tier athletics’
New Syracuse chancellor Mike Haynie said he considers sports to be a fundamental part of the school's business model.
CalMatters named a finalist in Toner Prize for Excellence in Local Political Reporting
The Toner Prizes, awarded by the Newhouse School, recognize the best political reporting and are named after Robin Toner ’76, the first woman to hold the position of national political correspondent for The New York Times.
Scientists just found the brain’s hidden defense against Alzheimer’s
A new study has uncovered why some brain cells are more resistant to Alzheimer’s damage than others. Researchers found a natural cleanup system that helps remove toxic tau protein before it can form harmful clumps. The study also shows that cellular stress can produce a dangerous tau fragment linked to Alzheimer’s. Strengthening the brain’s natural defenses could point the way to new treatments.
Scientists find the genetic switch that makes pancreatic cancer resist chemotherapy
Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form—but it gets shut down by an overactive KRAS-driven pathway. When researchers blocked that pathway, GATA6 levels rebounded and cancer cells became more sensitive to chemo. The discovery could help turn some of the toughest pancreatic tumours into ones doctors can better control.
Superagers' 'Secret Ingredient' May Be The Growth of New Brain Cells
Perhaps just one of many factors.
Chancellor Girod to attend White House college sports roundtable
University of Kansas Chancellor Doug Girod will attend President Trump's "Saving College Sports Roundtable," university sources confirmed.
KU chancellor Douglas Girod to attend White House college sports talk
KU chancellor Douglas Girod will be a part of a pivotal discussion about college sports. He’s set to attend a White House roundtable about this topic.
NBA power rankings: Is a new contender emerging out West?
The Minnesota Timberwolves have won six of their last seven games, and Anthony Edwards is excelling as both a scorer and a passer during this stretch.
Research roundup: Six cool science stories we almost missed
Smart underwear measures farts, brain cells play Doom, and AI discovers rules of an ancient game.
Apple Unveils iPad Air With M4 Chip, Increased RAM, Wi-Fi 7, and More
Apple today introduced a new iPad Air, with key upgrades including Apple's M4 chip for faster performance, an increased 12GB of RAM, Apple's N1 wireless networking chip with Wi-Fi 7 support, and Apple's custom C1X cellular modem. The new iPad Air looks identical to the previous-generation model, which is equipped with the M3 chip, 8GB of RAM, and Wi-Fi 6E support.
Conexeu Sciences Appoints Jean-Romain (JR) Falconnet as Head of Business Development & Licensing
Reno, Nevada--(Newsfile Corp. - March 2, 2026) - Conexeu Sciences Inc. ("Conexeu" or the "Company"), a biotechnology innovator redefining regenerative medicine through a next-generation extracellular matrix platform, is pleased to announce Jean-Romain (JR) Falconnet as Head of Business Development & Licensing.In his role at Conexeu, JR will lead business development, licensing strategy, and strategic partnerships—supporting the company's growth roadmap and expanding opportunities to bring...
Ancient Microbes Fused Into Earth’s First Complex Cells. Scientists Just Learned What Made It Possible.
Around 1.7 billion years ago, eukaryotes—the building blocks of complex life—first appeared on Earth, and now scientists have solved a longstanding riddle about their origin.
Submission Period Now Open for the 2026 Eric and Wendy Schmidt Awards for Excellence in Science Communications; $640,000 To Be Awarded
Submissions are now being accepted for the 2026 Eric and Wendy Schmidt Awards for Excellence in Science Communications. The awards honor exceptional science communicators, science journalists, and research scientists who have developed creative, original work that addresses issues and advances in science, engineering, and medicine for the general public.
Milken Institute School of Public Health, Social Mission Alliance Announce 2026 Awards for Excellence in Social Mission in Health Professions Education | Milken Institute School of Public Health | The George Washington University
The Social Mission Alliance announced the sixth cohort of Josiah Macy Jr. Foundation Awards for Excellence in Social Mission in Health Professions Education.
Top YSU business students earn elite honor society induction
The Youngstown State University chapter of Beta Gamma Sigma in the Williamson College of Business Administration celebrated academic excellence and leadership during its 27th annual Beta Gamma Sigma induction ceremony held Feb. 22 on campus.
Scientists reveal why a popular anti-aging compound may also fuel cancer
Polyamines—natural molecules found in every living cell—have become stars in the longevity world for their ability to boost cellular cleanup and support healthy aging. But there’s a dark twist: high levels of these same molecules are consistently seen in cancer, where tumors grow aggressively.
3 Seattle Mariners who hitting coach Seitzer is high on
Seattle Mariners hitting coach Kevin Seitzer thinks Julio Rodríguez will leave his slow starts behind, and is impressed by two up and coming hitters.
Anker’s latest noise-cancelling wireless headphones boast huge battery life and smart functionality
The Soundcore Space 2 feature a massive 70-hour battery life
New iron nanomaterial wipes out cancer cells without harming healthy tissue
Scientists at Oregon State University have engineered a powerful new nanomaterial that zeroes in on cancer cells and destroys them from the inside out. Designed to exploit cancer’s unique chemistry—its acidity and high hydrogen peroxide levels—the tiny iron-based structure sparks not one but two intense chemical reactions, flooding tumors with cell-damaging oxygen molecules. This dual attack overwhelms cancer cells with oxidative stress while sparing healthy tissue.
New iron nanomaterial wipes out cancer cells without harming healthy tissue
Scientists at Oregon State University have engineered a powerful new nanomaterial that zeroes in on cancer cells and destroys them from the inside out. Designed to exploit cancer’s unique chemistry—its acidity and high hydrogen peroxide levels—the tiny iron-based structure sparks not one but two intense chemical reactions, flooding tumors with cell-damaging oxygen molecules. This dual attack overwhelms cancer cells with oxidative stress while sparing healthy tissue.
Cook County public health grant threatened by federal funding cancellation
Grant funding for Cook County Public Health and Human Services (PHHS) is at risk after the Centers for Disease Control and Prevention (CDC) canceled millions of dollars in public health investments for Minnesota. The Public Health Infrastructure Grant awarded Cook County more than $30,000. Statewide, about $38 million in public health funding was canceled, effective...