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Trump supercharged ICE. Now battleground candidates look for a message

Republican and Democratic congressional candidates are wrestling with how to talk about immigration. They consistently call for a strong U.S.-Mexico border but then diverge, with some calling for ICE to be abolished while others support President Trump's immigration crackdown.

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Sep 27 • 6:00 AM EDT • Politics • latimes.com
These Democrats are running for Congress on Christian faith. Will it pay off?

It's rare for Democrats to make religion a centerpiece of their campaigns. But this midterm election cycle, a number of candidates for Congress are doing just that.

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Sep 27 • 6:00 AM EDT • Politics • wxxinews.org
Maine has more to do to boost access to mental health care, say providers and stakeholders

Mainers face significant waitlists for mental health care, despite the state taking steps to improve access in recent years.

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Sep 27 • 5:52 AM EDT • Health • mainepublic.org
Fresh off World Cup wins, Kansas City leaders say sports could be city's promising new brand

Those involved in the World Cup's KC2026 effort and economic development leaders say Kansas City can build a brand around its expertise in sports architecture and increasing its profile in sports media, tech, health and youth sports.

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Sep 27 • 5:00 AM EDT • Sports • kcur.org
Diamondbacks bullpen game disaster may cost them a playoff spot

The Diamondbacks snapped a six-game winning streak by losing a bullpen game that involved perplexing twists, turns and decisions.

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Sep 27 • 12:04 AM EDT • Sports • arizonasports.com
Connections: Sports Edition today: Hints and answers for Sept. 27, 2026, puzzle No. 734

Welcome to Connections: Sports Edition Coach — a spot to gather clues and discuss (and share) scores.

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Sep 27 • 12:00 AM EDT • Sports • nytimes.com
Lansing-Jackson TV market has booked $39 million in political ads … and counting

Candidates, parties and PACs have placed more than 20,000 spots on WLNS, WILX News 10, WLAJ and Fox 47, with more orders expected between now and Election Day.

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Sep 26 • 11:16 PM EDT • Politics • wkar.org
Health advisory for fecal bacteria at Residents Beach no longer in effect

Beachgoers at Residents Beach on Marco Island have the all-clear to return to the water after an advisory against swimming due to enterococcus levels

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Sep 26 • 7:38 PM EDT • Health • wgcu.org
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UCLA dominates in all phases of the game during rout of Maryland

Bob Chesney became the first UCLA coach to start his tenure 4-0 since 1949, steering the Bruins to a 54-3 Big Ten road victory over Maryland Saturday.

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Sep 26 • 4:59 PM EDT • Sports • latimes.com
Colts' Alec Pierce Officially Lands On IR, Replaced On Roster

The Indianapolis Colts placed wide receiver Alec Pierce on injured reserve on Saturday, replacing his roster spot with another receiver from the practice squad.

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Sep 26 • 4:35 PM EDT • Sports • sports.yahoo.com
David Jolly to national Democrats: Show me some money for governor's race

This week the national elections rating group Decision Desk HQ shifted the Florida governor’s race to a “Toss up,” saying Donalds has a 60% probability of winning, down from 68%.

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Sep 26 • 4:10 PM EDT • Politics • wlrn.org
Trump calls Iranian plan to reopen Strait of Hormuz not 'acceptable'

President Trump said he was rejecting an Iranian plan to reopen the Strait of Hormuz. The Iranian proposal is similar to a memorandum of understanding agreed upon by the U.S. and Iran back in June.

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Sep 26 • 4:08 PM EDT • Politics • npr.org
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Trump calls Iranian plan to reopen Strait of Hormuz not 'acceptable'

President Trump said he was rejecting an Iranian plan to reopen the Strait of Hormuz. The Iranian proposal is similar to a memorandum of understanding agreed upon by the U.S. and Iran back in June.

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Sep 26 • 4:08 PM EDT • Politics • kgou.org
Padres clinch playoff spot; seek home-field series

Padres notes - September 25

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Sep 26 • 2:40 PM EDT • Sports • sports.yahoo.com
What's the Most Overrated Business Advice?

Let us know the most overrated business advice you've gotten in the comments.Subscribe to The Hustle:🔗 https://clickhubspot.com/vu3lGet the 5-minute newsletter keeping 2M+ innovators in the loop🔗 https://clickhubspot.com/3klnAbout HubSpot: HubSpot is a customer platform that provides education, software, and support to help businesses grow better. The platform includes marketing, sales, service, commerce, operations, and website management products that start free and scale to meet our customers’ needs at any stage of growth. Today, thousands of customers around the world use HubSpot’s powerful and easy-to-use tools and apps to attract, engage, and delight customers.#TheHustle #HubSpot

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Sep 26 • 1:32 PM EDT • Business • finance.yahoo.com
Ocasio-Cortez downplays 2028 speculation, stresses 2026 elections

Rep. Alexandria Ocasio-Cortez said her focus is on helping Democrats win in 2026, downplaying speculation about a 2028 presidential bid.

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Sep 26 • 1:18 PM EDT • Politics • scrippsnews.com
Texts link Justin Baldoni’s crisis PR pro to 'smear' sites, complaint alleges

Top Hollywood publicist Melissa Nathan faces allegations of playing a key role in running 'smear' sites for embattled celebrities amid the Justin Baldoni legal saga. In a deposition, Nathan denied she was the mastermind behind the now-defunct stephaniejonesleaks.com.

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Sep 26 • 12:33 PM EDT • Entertainment • latimes.com
Propaganda or a PSA, Trump's latest ad blitz is paid for by you.

Criticism spills over on strategically timed ads paid for by the U.S. government touting the alleged achievements of President Donald Trump.

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Sep 26 • 12:00 PM EDT • Politics • latimes.com
Grand Canyon tour operator says some businesses have been set back worse than during COVID-19

Last year’s Dragon-Bravo Fire on the North Rim of the Grand Canyon and this August’s devastating floods that restricted lodging on the South Rim, have been a major disruption for local businesses who rely on tourists.

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Sep 26 • 10:13 AM EDT • Business • kjzz.org
Patriots Week 3 Roster Updates

The NFL season is in its third week. Everyone's favorite teams are playing, and the rosters are changing. For the New England Patriots, there are spots to fill. With all the injuries that have happened so far, someone needs to step up, and someone needs to be a backup for the backup. Who's Filling in […] The post Patriots Week 3 Roster Updates appeared first on Stadium Rant.

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Sep 26 • 10:02 AM EDT • Sports • sports.yahoo.com
Borussia Dortmund join Roma in race for Kvernadze

After exploring a myriad of prospects last summer without ever landing a spot, the solution to the right-footed left-back conundrum could be right near home. Located 90 kilometers from Rome, 23-year-o...

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Sep 26 • 8:35 AM EDT • Sports • sports.yahoo.com
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David Jolly implores national Democrats to help his campaign for governor

David Jolly took his case for governor to the Tampa Tiger Bay Club Friday.

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Sep 26 • 8:30 AM EDT • Politics • wusf.org
Ken Paxton to bring campaign tour to El Paso. Here’s when and where

Paxton’s “Protecting the Texas Promise” tour is scheduled to stop in El Paso next week. The event is free, though spots can be reserved.

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Sep 26 • 8:23 AM EDT • Politics • elpasotimes.com
Science Behind the Forecast: Don't like gloomy skies? Blame nimbostratus clouds

Every week WAVE 3 meteorologist Tawana Andrew breaks down what we know and what we don't about the climate and weather here in Louisville.

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Sep 26 • 8:00 AM EDT • Science • lpm.org
Purplish: ‘The Great Colorado Ballot-O-Rama’ Part I

This year’s ballot is lengthy, very lengthy, and packed with thorny topics.

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Sep 26 • 8:00 AM EDT • Politics • kunc.org
Meth is a key driver in Fiji's fast-growing HIV epidemic: 1 in 60 adults are affected

In mid-September, Fiji's government declared a national emergency because of a startling rise in HIV infections. The country's crystal meth epidemic is a strong contributing factor.

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Sep 26 • 7:31 AM EDT • Health • npr.org
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Got free health care? It's almost free at the Highlands County schools employee clinic

The new medical clinic should cost little to nothing for routine medical care and medications

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Sep 26 • 6:54 AM EDT • Health • wgcu.org
Funko warned it might not last 12 months. Its new CEO came from Netflix with a plan.

Funko, the company behind the big-headed Pop! figurines, warned last year it might not survive, squeezed by tariffs, canceled retail orders and its own overproduction. A new CEO based in Los Feliz is trying to turn it around.

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Sep 26 • 6:00 AM EDT • Entertainment • latimes.com
Funko warned it might not last 12 months. Its new CEO came from Netflix with a plan.

Funko, the company behind the big-headed Pop! figurines, warned last year it might not survive, squeezed by tariffs, canceled retail orders and its own overproduction. A new CEO based in Los Feliz is trying to turn it around.

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Sep 26 • 6:00 AM EDT • Business • latimes.com
The Best Early Prime Day Deals Ahead of Amazon’s Second Sale (2026)

Amazon Prime Big Deal Days officially begin on October 6 and 7, but I’ve already spotted early discounts on gear our team recommends.

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Sep 26 • 5:03 AM EDT • Technology • wired.com
Meal deliveries can save money and improve health. Will they survive Medicaid cuts?

Some states deliver meals to Medicaid patients that address their dietary needs. Evidence shows it aids recovery and saves healthcare costs, but federal budget cuts may lead some states to cancel it.

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Sep 26 • 5:00 AM EDT • Health • npr.org
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Pellegrini hoping to make first season appearance vs Como

Lorenzo Pellegrini is working to return to the spotlight with Roma. The Giallorossi midfielder is using the international break to regain top form and focus on the match against Como on October 11th a...

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Sep 26 • 4:20 AM EDT • Sports • sports.yahoo.com
😐 Neutral (25%)
Palace's Underrated Superstar and his Palace Future

Tyrick Mitchell's time at Palace may sometimes go out of the spotlight but he is one of Palace's most reliable performers.

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Sep 26 • 4:19 AM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Connections: Sports Edition today: Hints and answers for Sept. 26, 2026, puzzle No. 733

Welcome to Connections: Sports Edition Coach — a spot to gather clues and discuss (and share) scores.

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Sep 26 • 12:00 AM EDT • Sports • nytimes.com
Owner says fencing outside longtime Greektown liquor store hurts business, sues

Athens Liquor owner Ather Butris claims street festival fencing has become a barrier to his bottom line, prompting a lawsuit against the Greektown Neighborhood Partnership.

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Sep 25 • 11:55 PM EDT • Business • wxyz.com
Health and Safety Advisory issued after contaminated marijuana vaporizers sold at over 400 stores in Colorado

The Colorado Department of Public Health and Environment (CDPHE) has issued a health and safety advisory after contaminated "Regulated Marijuana Vaporizer Delivery Devices" were sold at 400+ stores

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Sep 25 • 11:04 PM EDT • Health • koaa.com
Patricia Smith named as president and CEO of the Yukon-Kuskokwim Health Corporation

Smith stepped in as interim president and CEO of the corporation in April, when Dan Winkelman stepped down from his role after 12 years. Now she has been formally appointed to the role.

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Sep 25 • 9:44 PM EDT • Health • kyuk.org
Debate over James Rodríguez's starting spot intensifies

The recent clásico between Atlético Nacional and Millonarios sparked debate among fans about the role James Rodríguez should take on in the team.Gradual integration and technical contributionThe mi...

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Sep 25 • 9:37 PM EDT • Sports • sports.yahoo.com
How to spot AI science slop

AI-generated science content is super prone to factual errors. Here's how to spot it… Lots of typos and grammatical errors used to signal that something wasn’t checked carefully. Now, it’s AI slop…

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Sep 25 • 8:00 PM EDT • Science • labmuffin.com
Virginia City businesses adapt after Montana Heritage Commission lease controversy

Virginia City businesses are closing out a tough season after steep lease hikes from the Montana Heritage Commission displaced several longtime operators.

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Sep 25 • 7:47 PM EDT • Business • kbzk.com
Deep dive
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Homewood BBQ spot improves as 5 other eateries fall below health standards

Homewood BBQ spot improves as 5 other eateries fall below health standards

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Sep 25 • 7:38 PM EDT • Health • wbrc.com
☹️ Negative (-13%)
For third time, Supreme Court rejects Missouri's bid for another GOP-leaning House district

The GOP wanted to redraw a district in Kansas City that had elected a Black Democrat. Six of the state's eight congressional districts favor Republicans.

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Sep 25 • 6:30 PM EDT • Politics • latimes.com
Supreme Court blocks Trump-backed Missouri congressional map

The ruling is a defeat for Republicans seeking to give their party an edge in the midterm elections for control of the House. It means voters will face a different map than the one used in the primary elections.

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Sep 25 • 6:06 PM EDT • Politics • npr.org
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Supreme Court blocks Trump-backed Missouri congressional map

The ruling is a defeat for Republicans seeking to give their party an edge in the midterm elections for control of the House. It means voters will face a different map than the one used in the primary elections.

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Sep 25 • 6:06 PM EDT • Politics • kgou.org
Latest Midterm Polls Reveal Bright Spots for Republicans

There has been a turnaround in Maine, our new poll shows.

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Sep 25 • 6:06 PM EDT • Politics • nytimes.com
A New York Times article claimed hostility by Mary Peltola. Will it affect Alaska’s Senate race?

Additional reporting shows conflicts between Alaskans and East Coast staff during Peltola’s term in Congress.

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Sep 25 • 5:55 PM EDT • Politics • alaskapublic.org
Dolly Parton recorded a song with Bono before she died

Dolly Parton recorded a duet with Bono just months before she died that will be included on U2's upcoming album 'Carnaval De Luz.'

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Sep 25 • 5:09 PM EDT • Entertainment • latimes.com
A grand display for Xi reveals the limits of Trump's summitry

The summit’s stark lack of substance surprised even the closest China watchers.

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Sep 25 • 5:04 PM EDT • Politics • latimes.com
$31M in federal grants target Oklahoma tribal nations' mental health, substance abuse prevention

The U.S. Department of Health and Human Services has announced $31 million will support more than a dozen tribal nations and organizations in Oklahoma, providing mental health and substance use prevention resources.

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Sep 25 • 4:37 PM EDT • Health • kgou.org
IowaWORKS offers weekly hiring opportunities for Des Moines employers

IowaWORKS is offering employers an opportunity to connect with job seekers through its Grab-A-Job Tuesdays weekly hiring series at the Des Moines IowaWORKS office at 200 Army Post Road. The program allows employers to promote open positions, conduct on-the-spot interviews and screenings, and collect candidate information for follow-up. According to IowaWORKS, 50 to 150 job…

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Sep 25 • 4:15 PM EDT • Business • businessrecord.com
TGIF: Ian Donnis’ Rhode Island politics roundup for Sept. 25, 2026

An early signal of how RI moved in a more progressive direction

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Sep 25 • 3:59 PM EDT • Politics • oceanstatemedia.org
“Same confidence”: Ho targets response after West Ham

Tottenham Hotspur return to league action on Sunday against Aston Villa, with Martin Ho using Friday’s press conference to reflect on how rotation disrupted his side’s rhythm in their last outing ...

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Sep 25 • 3:55 PM EDT • Sports • sports.yahoo.com
What does Meta’s Muse do that Spotify’s AI can’t?

Muse can make playlists, too. Its bigger pitch is connecting your listening to the rest of your plans.

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Sep 25 • 3:49 PM EDT • Technology • mashable.com
Disney star Dove Cameron marries Italian rock star Damiano David

On Thursday, 30-year-old Dove Cameron married 27-year-old Damiano David in a civil ceremony at the town hall in Montalcino, Italy.

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Sep 25 • 3:36 PM EDT • Entertainment • latimes.com
Political debates were once considered essential. Has that changed?

For most of the television era, the political debate had a pretty straightforward purpose: Put candidates next to each other, take away the script, and let voters watch. But with no top-of-ticket debates scheduled to happen in Florida this year, where does the debate stand?

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Sep 25 • 3:20 PM EDT • Politics • news.wfsu.org
Homewood BBQ spot improves as 5 other eateries fall below health standards

Five Jefferson County food establishments, American Deli, Jimmy Johns, Walmart Deli, Triple S Food Store and Dollar General, scored below 85 in health inspections, while Jim N' Nicks in Homewood cleared reinspection with a 97 after months out of compliance, according to JCDH.

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Sep 25 • 3:08 PM EDT • Health • wbrc.com
Quixote shutters supplying business, lays off 60 employees

Hudson Pacific-owned Quixote sold its grip, lighting and production supplies businesses to Cinelease, cutting about 60 jobs as Hollywood's production slump drags on.

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Sep 25 • 3:07 PM EDT • Entertainment • latimes.com
Quixote shutters supplying business, lays off 60 employees

Hudson Pacific-owned Quixote sold its grip, lighting and production supplies businesses to Cinelease, cutting about 60 jobs as Hollywood's production slump drags on.

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Sep 25 • 3:07 PM EDT • Business • latimes.com
Omar Blanco Takes the Spotlight at Greater Kendall Business Association!

Getting your Trinity Audio player ready... The Greater Kendall Business Association welcomed Omar Blanco as a special guest, bringing local business and community connections into the spotlight. Watch our video recap for highlights from his visit and a look inside the gathering. #OmarBlanco #GreaterKendall #GKBA #KendallBusiness #MiamiCommunityNews Connect To Your Customers & Grow Your Business […]

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Sep 25 • 3:03 PM EDT • Business • communitynewspapers.com
Biologists move unprecedented Orange County sea turtle eggs to protect them from hurricane-driven waves

The olive ridley sea turtle eggs will incubate at the Aquarium of the Pacific

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Sep 25 • 2:42 PM EDT • Science • latimes.com
Report: Bernard-Docker Injured, Red Wings Roster Spot in Doubt

A Red Wings defenseman's opening night roster spot is suddenly in doubt, and a prospect is waiting. #RedWings

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Sep 25 • 2:37 PM EDT • Sports • sports.yahoo.com
Why Hallmark Movies and John Wilson’s 'The History of Concrete' take the mundane so seriously

Hallmark movies and John Wilson’s “The History of Concrete” find comedy by taking mundane passions and situations seriously.

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Sep 25 • 2:37 PM EDT • Entertainment • latimes.com
From Miami to the UAE: Exploring the Next Business Connection

Getting your Trinity Audio player ready... Global business opportunities take center stage in Miami as the Greater Miami Chamber of Commerce and JP Global Advisors spotlight Ras Al Khaimah, United Arab Emirates. The September 24 event focuses on business expansion and investment opportunities, connecting South Florida’s business community with possibilities beyond U.S. borders. Connect To […]

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Sep 25 • 2:33 PM EDT • Business • communitynewspapers.com
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Anida Yoeu Ali is 'The Buddhist Bug' in a compelling exhibit at VPMA

Performance artist Anida Yoeu Ali's exhibit, 'Anida Yoeu Ali: The Buddhist Bug,' features a 328-foot-long performance installation of an orange bug that explores race, religion, feminism and immigration, and will weave in and out of the gallery rooms.

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Sep 25 • 1:47 PM EDT • Entertainment • latimes.com
Ed Sheeran's concerts at Gillette Stadium canceled

Ed Sheeran's Friday and Saturday concerts at Gillette Stadium in Foxborough, Mass., have been canceled 'due to severe weather warnings' in the region, Messina Touring announced Friday.

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Sep 25 • 1:24 PM EDT • Entertainment • latimes.com
José Javier Rodríguez launches multimillion-dollar ‘Give ’Em Hell’ statewide ad campaign

The 30-second spot follows poling showing him and the Republican incumbent statistically tied in the Attorney General’s race.

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Sep 25 • 1:23 PM EDT • Politics • floridapolitics.com
A data-sharing clause derailed U.S.-Zimbabwe health talks. Now all funding ends this month

The withdrawal casts uncertainty over programs to combat HIV and other diseases in a country where shortages often force patients to bring basic supplies such as bandages to clinics and buy their own medicines.

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Sep 25 • 12:56 PM EDT • Health • latimes.com
What is the Diamondbacks’ path to the 2026 MLB postseason?

PHOENIX – With just three games left in the 2026 MLB season, the Arizona Diamondbacks have created one final opportunity to make October. The D-backs enter the final weekend two games behind the Philadelphia Phillies for the National League’s final Wild Card spot.

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Sep 25 • 12:34 PM EDT • Sports • sports.yahoo.com
Encompass Health celebrates opening of new Bangor rehabilitation hospital

The for-profit health organization has expanded its footprint in recent years with plans to open hospitals in several locations around the country.

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Sep 25 • 12:26 PM EDT • Health • mainepublic.org
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Justices uphold Trump's expanded data checks to spot non-citizens who registered to vote

The Trump administration says Social Security data may help spot non-citizens who are registered to vote.

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Sep 25 • 12:11 PM EDT • Politics • latimes.com
Entertainment News: September 25, 2026

Get caught up on the latest in Hollywood, technology, and more with FOX 17 Morning Mix's Entertainment News.

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Sep 25 • 12:02 PM EDT • Entertainment • fox17online.com
UVM receives $19M grant to create a national neuroscience hub

The grant will fund a new observatory at the University of Vermont to help scientists research and better understand how brains and nervous systems work.

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Sep 25 • 12:01 PM EDT • Science • vermontpublic.org
AI Slop or IP Gold? The Business of Brainrot

This case is not merely about memes; it is a test case for how artists and IP law will continue to grapple with the commercialization efforts behind viral internet culture and new forms of digital creativity.

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Sep 25 • 11:30 AM EDT • Business • law.com
😐 Neutral (13%)
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What we know about Trump’s upcoming visit to Oklahoma

President Donald Trump is coming to Durant for a rally Thursday in the heart of the Choctaw reservation.

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Sep 25 • 11:24 AM EDT • Politics • kosu.org
iPad Mini 8 Leaked: A20 Pro Chip, Landscape Camera, and More

Apple's next-generation iPad mini will feature the A20 Pro chip, a rearranged front-facing camera, and a new speaker system, leaked code reveals. The information originates from Apple's own code (spotted by MacRumors contributor Aaron Perris) and also shows clear product images of the new iPad mini. Although images of the device only show the front, leaving any design changes of the rear or side profile unknown, there are still visible changes.

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Sep 25 • 11:18 AM EDT • Technology • macrumors.com
Exclusive: First Look at HomePod Mini 2 in Three New Colors

Apple's new HomePod mini will share the same design as the original model and come in five colors, MacRumors has found. The information originates from Apple's own code (spotted by MacRumors contributor Aaron Perris) and shows clear product images of the new models in all of their colors. The above image contains Apple's own icons, which specifically refer to a "HomePod mini 2". The new HomePod mini will come in green, pink, blue, white, and black.

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Sep 25 • 11:17 AM EDT • Technology • macrumors.com
Feel Good Friday: Toys 'R' Us' South Sound Return, a New Dog-Wellness Brand, and Local Business Honors

A toy brand plots its local comeback, a spot for pups opens in University Place, and more in this week's Feel Good Friday.

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Sep 25 • 11:00 AM EDT • Business • southsoundmag.com
Muslim Americans push back as Republican politicians stoke anti-Sharia rhetoric ahead of election

Muslim American civic leaders and scholars — in Texas and other states — are responding forcefully to this latest surge in anti-Sharia rhetoric that dates back more than 15 years.

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Sep 25 • 10:02 AM EDT • Politics • latimes.com
Ace Combat 8 Is Utterly Absurd--And Better Off For It

Bandai Namco Aces continues the Ace Combat series' upward trajectory into the stratosphere.

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Sep 25 • 10:00 AM EDT • Technology • gamespot.com
Guardians clinch a playoff spot again, edging the Red Sox 1-0 on Martínez homer

The Cleveland Guardians clinched a playoff spot for the third straight year with a 1-0 win over the Boston Red Sox.

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Sep 25 • 9:30 AM EDT • Sports • spectrumlocalnews.com
Pioneer of China NewCo model sued in US over trade secret misuse, double-dealing

A legal feud unfolding in New York is putting a spotlight on the work of a business development veteran who is credited for pioneering one of biopharma’s hottest dealmaking mechanism: the China “NewCo” model. In a lawsuit originally filed in New York state court and recently moved to federal court, China’s Lepu Medical Technology has alleged that biopharma business development consultant Su Zhang, who was hired to help shop its GLP-1 weight-loss candidates to Western partners, engaged in corporate double-dealing and trade secret leaks. According to the complaint, while acting as Lepu’s primary dealmaking liaison for a group of obesity and metabolic disease drug candidates, Zhang was secretly double-dipping as the acting chief business officer for a direct competitor, BrightGene Pharmaceutical. “She never adequately disclosed the role, never sought Lepu’s consent, and never proposed any safeguard,” Lepu alleged in its complaint, which was filed in July after Zhang’s consulting firm, CoDevCo, sought certain transaction-based success fees from its angry customer through an arbitration process in Singapore. Lepu, the parent company of Lepu Biopharma, has asked Zhang to pay back its $500,000 retainer and disgorge all benefits she received during the alleged breaches of fiduciary duty, plus other damages and relief. The company has also requested the court grant injunctions to protect Lepu’s trade secrets. The ill-fated partnership officially kicked off in December 2024, when Lepu tapped CoDevCo as its “exclusive business development mechanism” to identify collaborators for the company’s drug candidates. According to Lepu’s complaint, Zhang personally negotiated and signed the agreement as managing director for CoDevCo, which used her home address. Before the Lepu deal, Zhang made a name following a short stint as the global head of business development for Hengrui Pharmaceuticals. It was during her tenure that Hengrui signed a landmark deal granting exclusive rights for a portfolio of GLP-1 assets to Hercules, which was at that time newly established by a group of private equity and venture capital firms. In addition to the regular upfront and milestone payments, Hengrui also gained an equity stake in Hercules, which later became Kailera Therapeutics. The Hengrui-Hercules deal opened a new paradigm, where a Chinese biopharma company spins off certain early-stage assets to investors for further development through the creation of a new company abroad. The “NewCo” model quickly came into vogue as it allows Western investors to access high-potential assets originating from China at an early stage while giving the Chinese licensors an opportunity to reap long-term benefits through equity stakes in the new firms. The NewCo model proved its value when Kailera staged a record-breaking $625 million IPO on Nasdaq this April, merely two years into the Hengrui deal. Related Kailera CEO 'knew we were in a good spot' before obesity biotech's record-breaking $625M IPO On her LinkedIn page, Zhang described her work at Hengrui as “[b]uilding team and capability from the ground up,” forming NewCo and major pharma partnerships worth billions of dollars. Lepu clearly wanted that kind of track record to help boost its own cardiometabolic portfolio, which includes a range of assets for obesity, Type 2 diabetes, fatty liver disease and muscle preservation during weight loss treatment. “Lepu’s pipeline is very valuable, but only if Lepu could secure the right international partner to expand into the overseas market during the available commercial window,” the company argued in its complaint. The Chinese biotech said it had little knowledge of U.S. laws, customs or business practices in the business development field, and therefore “needed to rely entirely” on the expertise of Zhang and her team as the firm’s first engagement of a U.S.-based BD consultant. “Zhang’s dominating influence on the business development strategy is further evidenced by the fact that she personally controlled the business-development communications on behalf of Lepu with potential partners,” Lepu said in its complaint. After entering the deal, Zhang introduced Lepu to her four associates. According to Lepu’s version of events, all of them were allegedly employed at different time points to perform similar jobs at other Chinese companies that Lepu described as its competitors, while having access to Lepu’s confidential information. As such, Lepu described Zhang’s team as “a roster of individuals whose primary professional loyalty, by virtue of their concurrent full-time employment, ran to Lepu’s competitors.” As well as the specific examples set out in the case, a look at Lepu’s deals over the period suggests Zhang may have been involved in at least one transaction. During their partnership, Lepu, through its subsidiary Shanghai Minwei Biotechnology, also out-licensed its GLP-1/GIP/FGF21 agonist MWN105 to a NewCo called Sidera Bio in the fall of 2025. The deal included an upfront and near-term payment of $35 million, up to $1.01 billion in milestones, and a 9.99% stake in the Danish startup. It seems likely that Zhang facilitated the Minwei deal given that Lepu is on record as having used CoDevCo as its “exclusive business development mechanism.” The big shock for Lepu came in the form of a news article on June 25, 2025. The article, reporting on phase 2 data for BrightGene’s GLP-1/GIP receptor agonist BGM0504, identified Zhang as acting chief business officer of the Lepu rival. Blindsided by her association with BrightGene, Lepu confronted Zhang in July 2025. “Lepu was given assurances that there was nothing to be concerned about and told that Zhang would explain the matter to Lepu,” Lepu alleged in its complaint. “Zhang never did.” Lepu claimed that Zhang had the motive and opportunity to steer potential prospective partners toward BrightGene or other competitors. Later, in February 2026, one of Zhang’s associates joined BrightGene as the vice president for global business development, according to the complaint. Around the same time, Lepu sent written demand letters asking Zhang to account for her BrightGene role, identify what confidential data were shared with the rival firm, and provide any conflict-of-interest or firewall policies during the engagement. According to Lepu, neither CoDevCo nor Zhang answered the questions in their responses. Related Novo vs. KBP: How a $1.3B deal turned into a fraud accusation and an international legal fight In a motion to dismiss filed with the U.S. District Court in the Eastern District of New York on Sept. 4, Zhang’s legal team argued that Lepu’s agreement was signed with CoDevCo, and that an employee of the contractor does not owe fiduciary duties to the client. In its complaint, Lepu said: “That CoDevCo was the contracting entity does not insulate Zhang from personal liability for duties she personally undertook and personally breached.” Taking the argument one step further, the defending party argued that the consulting agreement “does not create a fiduciary relationship even between CoDevCo and Lepu; instead, it identifies CoDevCo as an independent contractor retained to market Lepu’s business to potential western partners.” Although CoDevCo was Lepu’s exclusive business-development contractor, there were no terms stipulating that the consulting firm should serve only Lepu, Zhang’s lawyer noted. As to Lepu’s claims that Zhang misappropriated trade secrets, the defendant argued that Lepu authorized the use of the information so Zhang’s team could perform their service per the agreement. In a rebuttal filed on Sept. 11, Lepu’s lawyer set out why they believe the Chinese biotech satisfied New York law’s misappropriation definition by alleging that the defendant used a trade secret “in breach of a duty or through improper means.” As an alternative to dismissing the suit, the defendant suggested the action should be stayed pending outcomes from the arbitration of a separate case in Singapore. While NewCo pioneer Zhang is defending her business arrangements, momentum behind the NewCo trend has continued unabated into 2026. Through August, Chinese biotech assets have spurred 15 NewCo deals this year, according to local trade publication PharmaDJ.

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Sep 25 • 8:40 AM EDT • Business • fiercebiotech.com
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