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Aleksandar Vucic concedes defeat in Serbia's parliamentary election, marking political shift

Aleksandar Vucic, who denounced the oppositional student movement as a foreign-led attempt to unseat him, led with virtually absolute power for 14 years.

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Oct 25 • 5:30 PM EDT • Politics • cbsnews.com
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Joan Crawford’s biggest rival wasn’t who you think: Inside the ‘Baby Jane’ star’s cattiest feud

Teeth marks, bruised egos, and knitting needles: The new book ‘Jungle Red’ goes inside the catty Joan Crawford movie that makes ‘Baby Jane’ look tame.

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Oct 25 • 5:25 PM EDT • Entertainment • ew.com
Aleksandar Vucic: Serbia's veteran ruler felled by student-led movement

The dominant force in Serbian politics for over 14 years, Aleksandar Vucic, who conceded defeat in a snap parliamentary poll on Sunday, rose from the wreckage of strongman Slobodan Milosevic's cabinet...

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Oct 25 • 5:20 PM EDT • Politics • yahoo.com
C.J. Stroud tosses two TDs in Week 7

Houston Texans quarterback C.J. Stroud completed 17 of 28 passes for 153 yards, two touchdowns and no interceptions in Week 7

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Oct 25 • 5:15 PM EDT • Sports • sports.yahoo.com
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Jalen Coker not a big factor in Week 7

Panthers WR Jalen Coker caught only one of four targets in Week 7 and posted only nine yards

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Oct 25 • 5:13 PM EDT • Sports • sports.yahoo.com
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Volkswagen Bet On Xpeng To Save Its China Business, But Buyers Aren't Showing Up

Volkswagen once dominated China’s automotive market, but the rise of domestic electric vehicle manufacturers has turned its fortunes upside down. Hoping to regain lost ground, the German automaker partnered with Chinese EV specialist Xpeng in ... Read more

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Oct 25 • 5:00 PM EDT • Business • finance.yahoo.com
Chuba Hubbard has decent outing in Week 7

Panthers RB Chuba Hubbard finishes with 33 rushing yards and 27 receiving yards

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Oct 25 • 4:53 PM EDT • Sports • sports.yahoo.com
🎥 Kylian Mbappé's lucky goal against FC Barcelona

Kylian Mbappé opened the scoring against FC Barcelona this Saturday, October 25.A truly unexpected goal.With both teams looking sluggish from the start, it took until the 42nd minute for the deadlock...

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Oct 25 • 4:52 PM EDT • Sports • sports.yahoo.com
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T.J. Hockenson finds end zone in Week 7 vs. Colts

Minnesota Vikings tight end T.J. Hockenson posted four receptions for 35 yards and a touchdown on five targets in Week 7

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Oct 25 • 4:51 PM EDT • Sports • sports.yahoo.com
Vučić concedes defeat in Serbian elections, says student movement won

The election was seen as a referendum on Vučić’s political dominance and the political system that has been in place in Serbia for more than a decade.

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Oct 25 • 4:51 PM EDT • Politics • euronews.com
Bryce Young throws one TD, two INTs in Week 7

Panthers QB Bryce Young finishes with season-low 163 yards and doubles INT total

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Oct 25 • 4:45 PM EDT • Sports • sports.yahoo.com
Justin Jefferson limited to 44 yards in Week 7

Minnesota Vikings wide receiver Justin Jefferson had four receptions for a team-high 44 yards on seven targets in Week 7

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Oct 25 • 4:38 PM EDT • Sports • sports.yahoo.com
☹️ Negative (-7%)
New York Giants' Cam Skattebo Just Saved His Job

New York Giants running back Cam Skattebo saved his job against the Houston Texans.

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Oct 25 • 4:37 PM EDT • Sports • sports.yahoo.com
Ravens surrender 35 unanswered points in stunning loss to Bengals

Baltimore squandered a 13-0 halftime lead as Joe Burrow threw four touchdown passes and Cincinnati handed the Ravens a 35-13 defeat

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Oct 25 • 4:33 PM EDT • Sports • sports.yahoo.com
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Four receptions for Chris Godwin Jr.

Buccaneers WR Chris Godwin Jr. leads team with four receptions in Week 7 win

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Oct 25 • 4:31 PM EDT • Sports • sports.yahoo.com
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Kyler Murray throws for 150 yards, TD in Week 7

Minnesota Vikings quarterback Kyler Murray completed 14 of 24 passes for 150 yards, one touchdown and no interceptions in Week 7

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Oct 25 • 4:16 PM EDT • Sports • sports.yahoo.com
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Kurt Warner Addresses Major Gaffe During Steelers Win vs. Saints

Kurt Warner knows Jaylen Warren’s name even better now. The former St. Louis Rams and Arizona Cardinals quarterback, who offered […]

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Oct 25 • 4:14 PM EDT • Sports • sports.yahoo.com
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Alaska Democratic Senate candidate Mary Peltola and her family suffer minor injuries in car crash

Peltola required medical attention after the accident, which happened when another vehicle crashed into the one transporting Peltola and her family, the campaign said.

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Oct 25 • 4:11 PM EDT • Politics • pbs.org
When will Myles Garrett return to the Rams?

Here's the latest on Myles Garrett as he continues recovering from early-season knee surgery.

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Oct 25 • 4:06 PM EDT • Sports • sports.yahoo.com
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Instant analysis after Bengals wake up, trounce Ravens

Quick notes and takeaways after the Bengals beat the Ravens in Week 7.

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Oct 25 • 3:57 PM EDT • Sports • sports.yahoo.com
Ex-Spur Jeremy Sochan becomes a Legend

The Dallas Legends used the top pick in Saturday's G League draft on Sochan, who will look to salvage an NBA career that has not gone as expected for the former lottery selection.

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Oct 25 • 3:53 PM EDT • Sports • sports.yahoo.com
Erick All leaves Week 7 game early

Bengals TE Erick All ruled out after suffering a knee injury in Week 7

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Oct 25 • 3:42 PM EDT • Sports • sports.yahoo.com
Michigan basketball gets reality check in exhibition loss vs Houston

Michigan writer Tony Garcia offers three observations from the Wolverines' 83-66 loss to Houston in its final exhibition.

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Oct 25 • 3:42 PM EDT • Sports • sports.yahoo.com
Two Georgia Bulldogs ranked among college football's top-25 players

Two Georgia Bulldogs earned top-15 spots on ESPN's midseason top 25 college football player rankings.

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Oct 25 • 3:33 PM EDT • Sports • sports.yahoo.com
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Primark's Business Doesn't Make Sense

In a world where fast fashion giants like Shein, Zara, and H&M drop thousands of new styles every day — and rake in billions through e-commerce — Primark is doing the unthinkable: thriving with zero online shopping. So what gives?*Want to Know the 5 Trends Changing Modern Retail? Find Out Here:* 🔗 https://clickhubspot.com/d13ac2In this video, we take you inside Primark’s weirdly brilliant business model — a model that’s stuck in the past on purpose. From warehouse optimization and floor-ready freight shipments to why the pandemic didn’t push them online, we unpack how this low-cost retail giant has managed to defy digital norms… and make it work.This isn’t just about one brand. It’s a story about modern retail expectations — and what it actually takes to meet (or reject) them.Subscribe to The Hustle:🔗 https://clickhubspot.com/vu3lGet the 5-minute newsletter keeping 2M+ innovators in the loop🔗 https://clickhubspot.com/3klnAbout HubSpot: HubSpot is a customer platform that provides education, software, and support to help businesses grow better. The platform includes marketing, sales, service, commerce, operations, and website management products that start free and scale to meet our customers’ needs at any stage of growth. Today, thousands of customers around the world use HubSpot’s powerful and easy-to-use tools and apps to attract, engage, and delight customers.#TheHustle #HubSpot

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Oct 25 • 3:31 PM EDT • Business • finance.yahoo.com
Rep. Carbajal Meets with Cottage Health’s Head Honchos in Santa Barbara as They Brace for ‘Big Beautiful Bill’ Impacts

Trump’s bill expected to leave close to 40,000 Central Coast residents without health coverage, another 37,000 with higher premiums, and a roughly $40 million initial impact on Cottage.

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Oct 25 • 3:30 PM EDT • Health • independent.com
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Des Moines bishop says White House 'exploited' visit for politics

Bishop William Joensen was one of several invited to the White House for a private meeting they say is being used for "partisan political purposes."

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Oct 25 • 3:28 PM EDT • Politics • desmoinesregister.com
When will Jeremiyah Love return to the Cardinals?

Here's the latest on Jeremiyah Love's status for the rebuilding Cardinals.

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Oct 25 • 3:20 PM EDT • Sports • sports.yahoo.com
Cardinals vs. Broncos live updates, analysis, highlights, scoring

We have live updates of the Cardinals-Broncos game in Week 7. Keep up with pregame, in-game and postgame coverage.

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Oct 25 • 3:18 PM EDT • Sports • sports.yahoo.com
NZ’s hidden chronic health burden is even bigger than we thought

New research reveals a major gap in how chronic illness is measured, with implications for planning and funding healthcare in New Zealand.

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Oct 25 • 3:10 PM EDT • Health • theconversation.com
USC Drops Out of AP Top 25 Poll After Wisconsin Loss, UCLA Rises Again

Both the USC Trojans and the UCLA Bruins had their rankings in the Associated Press Top 25 poll following their results from Saturday. View this post on Instagram A post shared by LA Sports Report (@lasportsreport) What Happened to USC’s Ranking? Following their loss to Wisconsin on Saturday, USC dropped out of the Top 25. […] The post USC Drops Out of AP Top 25 Poll After Wisconsin Loss, UCLA Rises Again appeared first on LA Sports Report.

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Oct 25 • 3:07 PM EDT • Sports • sports.yahoo.com
Puka Nacua active for Week 7 vs. Raiders

Los Angeles Rams wide receiver Puka Nacua is active for the Week 7 game

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Oct 25 • 3:05 PM EDT • Sports • sports.yahoo.com
Dodgers’ De Paula Faces Key Defensive Test

Josue De Paula impressed the Los Angeles Dodgers with his bat during his major-league debut. Can he do the same with his defense?

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Oct 25 • 3:04 PM EDT • Sports • sports.yahoo.com
Lions Week 7 inactives: EDGE Ahmed Hassanein OUT vs. Packers
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Oct 25 • 2:59 PM EDT • Sports • sports.yahoo.com
Asher Grunis steps down from leading Submarine Affair commission due to health concerns

Supreme Court President Isaac Amit appointed retired Supreme Court justice Zvi Zylbertal to replace Grunis and lead the commission on Sunday.

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Oct 25 • 2:58 PM EDT • Health • jpost.com
☹️ Negative (-4%)
Christian McCaffrey able to return to Week 7 game

49ers RB Christian McCaffrey returns to Week 7 game after missing time with thigh issue

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Oct 25 • 2:56 PM EDT • Sports • sports.yahoo.com
After arts festival, San Francisco's Mid-Market businesses look for signs of a turnaround
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Oct 25 • 2:54 PM EDT • Business • cbsnews.com
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Santa Ynez Tribal Health Clinic to Salute Veterans with Free Dental Services at Annual 'Veterans Smile Day' Event

Credit: Courtesy SANTA YNEZ, CA – October 21, 2026 – The Santa Ynez Tribal Health Clinic (SYTHC) will salute veterans with free dental services at its

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Oct 25 • 2:51 PM EDT • Health • independent.com
Freddy Peralta was beloved in Milwaukee. Now he stands in Brewers’ World Series path
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Oct 25 • 2:48 PM EDT • Sports • sports.yahoo.com
Week 7 inactives for Broncos

Broncos have declared seven players inactive for Week 7

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Oct 25 • 2:46 PM EDT • Sports • sports.yahoo.com
Gina Hinojosa says there's "deep disappointment in both political parties" in Texas right now
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Oct 25 • 2:46 PM EDT • Politics • cbsnews.com
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Cardinals Week 7 inactives

Cardinals announce seven inactives ahead of Week 7 game

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Oct 25 • 2:45 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
“Business as usual” – PSG coach refuses to give his players an excuse after triple blow

PSG are missing some important players, but that’s not an excuse says manager Luis Enrique, who still expects the best.If you enjoy PSG Talk coverage and want to see more of it, add us as a preferre...

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Oct 25 • 2:42 PM EDT • Business • sports.yahoo.com
Three Premier League talking points

Michael Carrick was pushed to the brink of the sack by Manchester United's latest debacle on Sunday.AFP Sport looks at three talking points from the weekend's action: Walls closing in on Carrick Michael Carrick's future as Manchester United boss was already hanging by a thread before Bournemouth inflicted what is likely to be a brutal last act for the former England midfielder at Old Trafford.

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Oct 25 • 2:36 PM EDT • Sports • sports.yahoo.com
Alaska Democratic Senate candidate Mary Peltola and her family suffer minor injuries in car crash

Alaska’s Democratic Senate candidate Mary Peltola and her family suffered minor injuries Saturday in a car crash while driving to a campaign stop, her campaign said.

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Oct 25 • 2:30 PM EDT • Politics • news4jax.com
‘I love spending time with them’: Lewis Hamilton opens up about Kim Kardashian’s kids

Lewis Hamilton and Kim Kardashian have been one of the most talked-about couples in sports and entertainment this year, but the seven-time Formula 1 world champion has rarely said much about the relat...

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Oct 25 • 2:28 PM EDT • Entertainment • yahoo.com
Nigeria widens hunt for possible Ebola cases

Nigeria has widened a hunt for potential Ebola cases, with an additional nine contacts traced, health authorities said Sunday.The initial 44 contacts were health care workers, while the additional nin...

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Oct 25 • 2:26 PM EDT • Health • yahoo.com
The Future of IBD Treatment: 4 Promising Therapies to Know About

New treatments are in development for inflammatory bowel diseases like Crohn’s disease and ulcerative colitis. Find out what experts say you should know.

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Oct 25 • 2:21 PM EDT • Health • health.yahoo.com
Blanche says Trump isn't trying to meddle with Alaska election results by suing over Senate race

Blanche told CNN's “State of the Union” that President Donald Trump, who said Friday that he was "the one that said do it,” is not trying to overturn state election results “in any way, shape or form” on the cusp of the Nov. 3 election.

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Oct 25 • 2:19 PM EDT • Politics • pbs.org
Jordan FA chief says AFC Congress ‘pure politics’ at behest of Infantino
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Oct 25 • 2:05 PM EDT • Politics • aljazeera.com
Inside 26-year-old’s club for million-dollar Chattanooga business owners

At 2nd American Restaurant on Thursday night, around 85 entrepreneurs who have scaled their businesses to at least $1 million in annual revenue sat to a family-style meal of beef cheek roast, airline chicken and the restaurant's signature bowl of mashed potatoes.

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Oct 25 • 2:01 PM EDT • Business • timesfreepress.com
Uganda tightens Ebola border controls and requires returnees from Congo to pay for quarantine

Uganda is reinforcing existing border controls requiring citizens returning from Congo to undergo 21 days of quarantine at their own expense, the Health Ministry said Sunday, as investigators examine how a woman who traveled from Uganda to Nigeria contracted Ebola.

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Oct 25 • 1:45 PM EDT • Health • seattletimes.com
Uganda tightens Ebola border controls and requires returnees from Congo to pay for quarantine

Uganda is reinforcing existing border controls requiring citizens returning from Congo to undergo 21 days of quarantine at their own expense, the Health Ministry said Sunday, as investigators examine how a woman who traveled from Uganda to Nigeria cont...

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Oct 25 • 1:44 PM EDT • Health • abcnews.com
Three receptions for Germie Bernard

Steelers WR Germie Bernard catches three of his five targets in Week 7 win

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Oct 25 • 1:40 PM EDT • Sports • sports.yahoo.com
College GameDay On-Site for Gophers vs Hoosiers

The Minnesota Gophers are coming off a big win over Iowa. And now College GameDay is going with the to Bloomington Saturday for the game @ Indiana.

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Oct 25 • 1:35 PM EDT • Sports • sports.yahoo.com
Steelers stock report after Week 7 win over Saints

Stock up, stock down, after the Steelers Week 7 win in Paris over the New Orleans Saints.

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Oct 25 • 1:35 PM EDT • Sports • sports.yahoo.com
Professor Katherine McNeill Inducted Into Massachusetts Science Educators Hall of Fame

Katherine L. McNeill was inducted into the Massachusetts Science Educators Hall of Fame on Friday in recognition of her two decades of work in science education.

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Oct 25 • 1:33 PM EDT • Science • bcheights.com
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Chris Olave targeted 10 times in Week 7

New Orleans wide receiver Chris Olave went for six receptions for 56 yards on 10 targets in Week 7

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Oct 25 • 1:33 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Google's privacy policy now has a loophole for using your Gmail and Photos data in ads

The change sits in Google's updated privacy policy, which took effect on October 16 and was first spotted by Android Authority. The policy has long said, "We...

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Oct 25 • 1:33 PM EDT • Technology • techspot.com
Schefter: Seahawks among teams ‘expected to consider’ Jonathan Taylor trade

The Seahawks are “pondering” adding Taylor in hopes of saving their run game.

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Oct 25 • 1:32 PM EDT • Sports • sports.yahoo.com
☹️ Negative (-10%)
Steelers Now Postgame: Steelers 16, Saints 10

Pittsburgh Steelers Postgame: Join Alan Saunders and Jobe Morrison after the Steelers’ Week 7 win over the Saints on YouTube, […]

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Oct 25 • 1:18 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
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How To Build A Cheap Home Server To Save Money On Subscriptions

You can turn an old laptop, a computer, or even a Raspberry Pi into a cheap media server, but it's best to run a Linux distribution for maximum compatibility.

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Oct 25 • 1:17 PM EDT • Technology • bgr.com
Nico Williams publicly disavows his agent over Barcelona transfer claims

Barcelona’s long and drawn-out pursuit of Nico Williams has become one of the more familiar sagas of recent transfer windows.The Athletic Club winger ultimately opted to stay at San Mames, snubbing ...

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Oct 25 • 1:17 PM EDT • Sports • sports.yahoo.com
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New Trump housing order targets mortgage and title insurers

A White House plan to pull private mortgage insurance off loans sooner, and to let refinancing borrowers skip the lender's title policy, affects two insurance lines that say they already help keep costs down

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Oct 25 • 1:09 PM EDT • Business • insurancebusinessmag.com
Carrick ‘not expecting’ Man United crisis talks despite Bournemouth defeat

Michael Carrick said he is ‘not expecting’ imminent talks about his future despite Manchester United’s latest defeat.Carrick’s position as head coach looks under threat after Manchester United...

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Oct 25 • 1:08 PM EDT • Sports • sports.yahoo.com
Steelers beat Saints to win first NFL game in Paris

The Pittsburgh Steelers defeated the New Orleans Saints 16-10 on Sunday to win the first-ever NFL regular season game in Paris. The low-scoring game had only one touchdown for each team.

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Oct 25 • 1:03 PM EDT • Sports • sports.yahoo.com
Business People: Evereve names industry vet Sarah Clary to advise on creative

RETAIL Evereve, an Edina-based women’s fashion retailer, announced it has named Sarah Clary as advisory chief creative officer. Clary previously has led creative direction campaigns and brand strategy for Hill House Home, Veronica…

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Oct 25 • 1:01 PM EDT • Business • twincities.com
Jaylen Warren surpasses 100-yard mark in Week 7

Steelers RB Jaylen Warren rushes for at least 100 yards for third time this season

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Oct 25 • 12:59 PM EDT • Sports • sports.yahoo.com
Oregon fires offensive coordinator Drew Mehringer after team scored just 10 points in loss to Illinois

Saturday's loss marked the third straight game in which Oregon scored under 20 points.

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Oct 25 • 12:57 PM EDT • Sports • sports.yahoo.com
Jay Glazer Shares Jalen Hurts Health Update, NFL And NFLPA Joint Investigation

On "FOX NFL Sunday," Jay Glazer shared the latest on Jalen Hurts' health and said that the NFL and NFLPA are doing a joint investigation.

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Oct 25 • 12:52 PM EDT • Health • foxsports.com
Blanche says Trump isn’t trying to meddle with Alaska election results by suing over Senate race

WASHINGTON (AP) — Attorney General Todd Blanche on Sunday defended the Trump administration's lawsuit to block certification of Alaska's Senate results if Repub

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Oct 25 • 12:51 PM EDT • Politics • wtop.com
Blanche says Trump isn't trying to meddle with Alaska election results by suing over Senate race

Attorney General Todd Blanche is defending the Trump administration’s lawsuit to block certification of Alaska's Senate results if incumbent Republican Dan Sullivan loses the race.

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Oct 25 • 12:49 PM EDT • Politics • news4jax.com
Blanche says Trump isn't trying to meddle with Alaska election results by suing over Senate race

Attorney General Todd Blanche is defending the Trump administration’s lawsuit to block certification of Alaska's Senate results if incumbent Republican Dan Sullivan loses the race.

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Oct 25 • 12:49 PM EDT • Politics • ksat.com
Aaron Rodgers throws for 212 yards in Week 7

Steelers QB Aaron Rodgers sees multiple TD streak snapped in Week 7 win

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Oct 25 • 12:47 PM EDT • Sports • sports.yahoo.com
Warren, Steelers stiff-arm Saints for 16-10 Paris win

Jaylen Warren had another big day and the Pittsburgh Steelers overcame some red-zone inefficiency to beat the New Orleans Saints.

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Oct 25 • 12:42 PM EDT • Sports • sports.yahoo.com
Police: Lancaster County health care worker assaulted

Incident occurred at WellSpan Hospital in Ephrata Borough, according to police.

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Oct 25 • 12:42 PM EDT • Health • wgal.com
Saints Lose Defensive Battle in Paris Against Steelers

A very winnable game that a better team would have won.

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Oct 25 • 12:36 PM EDT • Sports • sports.yahoo.com
Jaylen Warren and the Steelers run over the Saints in Paris
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Oct 25 • 12:35 PM EDT • Sports • sports.yahoo.com
Browns injury update: Is Denzel Ward playing against the Titans?

The Browns will enjoy the presence of their top cornerback in Week 7.

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Oct 25 • 12:22 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Kansas at Duke: Exhibition OGT

Kansas basketball hopes to follow the football team with a win today. Yeah, this game doesn’t count, but any time you’re playing Duke you want to win. Plus, this exhibition game is a big enough deal that ESPN is broadcasting it live (probably because they know everyone else will be watching football. I’m probably going […]

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Oct 25 • 12:21 PM EDT • Sports • sports.yahoo.com
😐 Neutral (6%)
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Kings' Veterans Praise Rookie Acuff After 33-Point Showing

The Sacramento Kings are yet to get a win, but Darius Acuff Jr. looks like the high-octane guard that the franchise so desperately needs. Coming off a 33-point outburst, how will Acuff play against the Memphis Grizzlies?

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Oct 25 • 12:13 PM EDT • Sports • sports.yahoo.com
Week 7 inactives for Ravens

Baltimore declares five players inactive versus Cincinnati

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Oct 25 • 12:06 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Apollo: AI has delivered 'zero financial payoff' to corporate America

Only tech companies are seeing growth from the AI boom, Apollo Global Management said.

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Oct 25 • 12:02 PM EDT • Business • businessinsider.com
Is having urine the color of Mountain Dew normal?

A Trump administration doctor says neon yellow urine is normal because of diets consisting entirely of meat and fermented foods. Here’s what experts say

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Oct 25 • 12:00 PM EDT • Health • health.yahoo.com
😐 Neutral (12%)
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57%
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Giants at Texans live game discussion for Week 7

We, who are about to watch Texans football, salute you.

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Oct 25 • 12:00 PM EDT • Sports • sports.yahoo.com
Browns Week 7 inactives: Who's in, who's out?

The Browns are the healthiest they have been in some time as they take on the Titans in Week 7.

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Oct 25 • 11:59 AM EDT • Sports • sports.yahoo.com
Trick-or-treaters descend on Callow Avenue for Calloween

Photos from Charleston Business District's annual Calloween event on Saturday, Oct. 24. ·

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Oct 25 • 11:57 AM EDT • Business • kitsapsun.com
RJW Logistics to open second Northwest Arkansas office

Chicago-based RJW Logistics Group, which has a Bentonville office, plans to open an additional Northwest Arkansas office amid client growth and to support demand for a new logistics program offered...

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Oct 25 • 11:55 AM EDT • Business • talkbusiness.net
2 political experts question Chicago Mayor Brandon Johnson's tax proposals for 2027 budget
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Oct 25 • 11:55 AM EDT • Politics • cbsnews.com
High-Signal Publisher
Connections: Law firms hire attorneys for NWA offices

Two Little Rock-based law firms have hired attorneys for their Northwest Arkansas offices, and the Single Parent Scholarship Fund of Northwest Arkansas recently announced new board members. NEW HIRES Banking...

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Oct 25 • 11:50 AM EDT • Politics • talkbusiness.net
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Connections: Law firms hire attorneys for NWA offices

Two Little Rock-based law firms have hired attorneys for their Northwest Arkansas offices, and the Single Parent Scholarship Fund of Northwest Arkansas recently announced new board members. NEW HIRES Banking...

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Oct 25 • 11:50 AM EDT • Business • talkbusiness.net
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Selena Gomez's vaping admission highlights hidden health risks doctors say millions face daily

Selena Gomez called vaping "stupid" after it altered her voice, but doctors warn the health risks go beyond vocal cord damage for millions.

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Oct 25 • 11:48 AM EDT • Health • foxnews.com
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals

Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.

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Oct 25 • 11:30 AM EDT • Health • fiercebiotech.com
South Texas Health System (@stxhealthsystem)

1 likes, 1 comments - stxhealthsystem on October 25, 2026: "Exceptional Care Starts With You: Nurses play a vital role in every patient journey, providing the compassionate, skilled care that helps make South Texas Health System’s 12 facilities a trusted healthcare resource for communities across the Rio Grande Valley. If you're passionate about making a difference and delivering exceptional patient care, now is your opportunity to join the largest integrated healthcare network in the region. STHS is seeking dedicated and compassionate registered nurses to join its team at four acute care hospitals, a behavioral health hospital and seven freestanding emergency departments. Become part of a team committed to clinical excellence, collaboration and compassionate care. To view current openings and apply, visit the STHS careers page at the link in our bio.".

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Oct 25 • 11:18 AM EDT • Health • instagram.com
California election officials frustrated, rattled by DOJ demand to sequester 'noncitizen' ballots

The administration has insisted that immigrants voting is a major problem nationwide, when in fact it is quite rare, as even its own investigations have shown.

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Oct 25 • 11:17 AM EDT • Politics • pbs.org
Syria’s Democratic Transition: Building Institutions Alongside Political Competition

Syria’s post-Assad transition has revived debate over when to legalize political parties. Parties are essential to political competition,

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Oct 25 • 11:16 AM EDT • Politics • fairobserver.com
Robinson, Baker have tough talk about the offense

Robinson, Baker have tough talk about the offense

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Oct 25 • 11:15 AM EDT • Sports • sports.yahoo.com
Jalen Duren out at least two weeks

Jalen Duren out at least two weeks

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Oct 25 • 11:04 AM EDT • Sports • sports.yahoo.com
Wrexham’s Summer Striker Decision Faces Fresh Scrutiny After Blackburn Defeat

Wrexham’s decision to back their current centre-forwards has become a renewed talking point after Saturday’s 2–0 defeat at Blackburn Rovers exposed the gap between attacking activity and a meaningful goal threat.

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Oct 25 • 11:00 AM EDT • Sports • sports.yahoo.com
Three Days Grace in San Antonio: What to know

The Canadian rockers are bringing their Alienation Tour to town. Here are the details on tickets, parking and more.

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Oct 25 • 11:00 AM EDT • Entertainment • expressnews.com