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ARK Invest Bets One Business Can Lift Tesla Stock to $4,400
ARK Invest’s open-source model values Tesla at about $4,400 per share in 2031, with robotaxis at 80% of enterprise value.
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)
Texas Football Prediction Has Longhorns Making $50 Million Steve Sarkisian Decision
Texas has gone from No. 1 to two straight defeats, and one college football analyst believes another disappointing finish could be bad news for Steve Sarkisian. The post Texas Football Prediction Has Longhorns Making $50 Million Steve Sarkisian Decision appeared first on HEAVY.
Pedri: Lamine Yamal shouldn't be compared to Lionel Messi
Pedri believes Lamine Yamal should not be compared to anyone, insisting that measuring the youngster against Lionel Messi is "complicated" because it means comparing him to "the best player in history...
Wow, Andoni Iraola now wants Spanish superstar to join Liverpool
Andoni Iraola has requested Liverpool to sign an exciting Spanish midfielder. Julian Ward has ushered in Liverpool’s new era without making too much noise. There has been no grand announcement or bi...
Gwyneth Paltrow sets first lead TV role in The Apology
Gwyneth Paltrow's last major onscreen role was in the 2025 film, Marty Supreme.
Whither Vladimir? (Part 1)
It’s no secret that a big part of the Blue Jays’ disappointing 2026 was the result of a disastrous season by superstar first baseman Vladimir Guerrero jr. Vlad’s offensive production cratered, from an average wRC+ of 139 from 2023-2025 to 95 this past season. If the team’s going to get back into contention in 2027 […]
English right-back is coming to Liverpool
An exciting right-back is coming to Liverpool's first-team. The right-back position is something the Reds have failed to figure out for a while. For close to a decade it was so easy for Liverpool.In T...
The best quotes about Eric Cantona
Eric Cantona remains one of the Premier League's most impactful footballers. Cantona was the signing that proved to be the catalyst behind Manchester United's dominance of the division, helping break ...
🗞️ A gala night in Paris: Tuesday's front pages
The front pages of Europe's sports newspapers this Tuesday, October 20, focus on a thrilling day of Champions League action, with the clash between PSG and Barcelona taking centre stage. Meanwhile, in...
Roland n/vision: the first Boutique wavetable Synthesizer
Roland n/vision is the first bi-timbral wavetable Synthesizer in the Boutique format with two oscillators, FX, and a step sequencer.
Pellegrini and Lulli confirmed to start vs Slovan
Roma are back in the hunt for a Champions League victory, with Malen ready to reclaim the center of attack. After the draw against Fenerbahce and the bitter defeat against Real Madrid, the Giallorossi...
Penguins Make Brutal Injury Announcement Against Mammoth
The Pittsburgh Penguins were in action on Monday against the Utah Mammoth, making a visit to Salt Lake City to take on their hosts at Delta Center. Unfortunately, they were defeated by a 5-4 final score – but that wasn’t the only loss they suffered.Not only did they lose the game, but the Penguins also […] The post Penguins Make Brutal Injury Announcement Against Mammoth appeared first on HEAVY.
Earnings To Watch: Elevance Health (ELV) Reports Q3 Results Tomorrow
Health insurance provider Elevance Health (NYSE:ELV) will be reporting results this Wednesday before market hours. Here’s what investors should know.
Auburn Linebacker Xavier Atkins Dismissed From Football Program
Auburn linebacker Xavier Atkins has reportedly been dismissed from the football program following a disciplinary issue that sidelined him against Georgia. With Atkins no longer on the roster, Alex Golesh and DJ Durkin must rely on Elijah Melendez, Bryce Deas and De'Marcus Riddick against LSU.
Apple explains new Safari ad tracking privacy restrictions
Apple's latest privacy crackdown is rattling the online ad industry. And it isn't backing down.
College students more likely to vote this election; Ohio State political leaders and experts reflect on why that is
With midterm elections less than a month away, college students are more likely than ever to head to the polls and cast their votes, new data suggests. As many as 66 percent of college students will vote in the 2026 midterms, according to an August survey conducted by the Center for Information and Research on […]
49ers, Jaguars Floated Trade Idea Involving $14.6 Million Player
The San Francisco 49ers appear to be one of the buyers ahead of the Nov. 10 trade deadline. So far this 2026 NFL season, the Niners have established themselves as a Super Bowl contender. Despite the impressive start to the campaign, San Francisco does have areas of concern such as the wide receiver position. During […] The post 49ers, Jaguars Floated Trade Idea Involving $14.6 Million Player appeared first on HEAVY.
Liam Coen Shares Message He Gave Jaguars Heading Into Bye Week
The Jaguars head into their bye week coming off a tough loss, but head coach Liam Coen is confident they will fix their issues during their break.
Middling production from Brock Purdy in Week 6
Brock Purdy passed for 264 yards and a score in Week 6 against the Commanders, though most of that damage came before halftime.
Calcium-rich whey permeate improves bone health in postmenopausal women, study finds
AFI AFI COPENHAGEN, Denmark, Oct. 20, 2026 (GLOBE NEWSWIRE) -- Twice-daily supplementation with calcium-rich whey permeate supports the maintenance of bone mineral density in postmenopausal women, according to a 12-month clinical study.[1] Declining oestrogen levels during menopause can accelerate bone loss and reduce bone mineral density, increasing osteoporosis risk. The findings come from the RENEW project, a research collaboration investigating how calcium-rich permeate from whey production
Week 6 Linebacker Usage and Review
Steve Hungarter uses defensive snap percentages from Weeks 4-6 with other season-to-date data to analyze off-ball linebackers entering Week 7.
Chig Okonkwo leads team in receiving
Chig Okonkwo led the club in both receptions and receiving yards during Washington's Week 6 loss to the 49ers.
Jacobe Smith Accepts Short Notice Fight for UFC Vegas 123
After a quick win earlier this month against Bruce Whitehead, Jacobe Smith already has his next fight booked. The undefeated welterweight takes on Randy Brown at UFC Vegas 123 in Las Vegas on October 31st. Brown was without an opponent after Carlos Leal pulled out due to an injury. Multiple sources have confirmed the fight […] The post Jacobe Smith Accepts Short Notice Fight for UFC Vegas 123 appeared first on HEAVY.
An Intro to New Orioles GM Jared Banner
The Baltimore Orioles made a front-office shakeup on Monday, bringing in assistant general manager of the Chicago Cubs, Jared Banner, to become the new general manager alongside President of Baseball Operations Mike Elias. Banner, who served as the Cubs' assistant GM from 2024 to 2026, joined after Elias expressed a desire to add "fresh voices" …
Michel Sanchez Provides Injury Update On Ajax Defender Daley Blind
Michel Sanchez has revealed that Daley Blind is nearing a return to action.
Lil Jon recalls learning man who raised him isn’t his biological father
The rapper writes about the experience in his new memoir, “I Only Shout So You Can Hear Me.”
75% of foreign parts found in Russian anti-jamming tech from US firms
Russia's Kometa systems for Shahed drones and Iskander-M missiles were found with 28 chips and other electronics made by US firms, per GUR.
Former Chiefs Starting QB Could Help Eagles Replace Jalen Hurts
Former Kansas City Chiefs quarterback Gardner Minshew could help the Philadelphia Eagles after a season-ending setback for Jalen Hurts. The post Former Chiefs Starting QB Could Help Eagles Replace Jalen Hurts appeared first on HEAVY.
Billy Bush sounds off about fight with author Amy Griffin at Jennifer Meyer’s star-studded wedding
Bush claims the author of “The Tell” confronted him over his coverage of her legal battle with a former classmate.
Rangers Find Their Offensive Rhythm In Win Over Ducks
The New York Rangers’ offense came alive on Monday night at Madison Square Garden, en route to a decisive 5-2 victory over the Anaheim Ducks.
Cisco president used AI agents to filter $9,000 worth of subscriptions
One of them, which costs him $20 a month, recently saved him more than $1,000 in subscription bills.
I sold my apartment and cashed out my pension to build a chip startup
Hans Hasselby-Andersen quit his engineering job during the 2008 financial crisis with four kids and spent a year raising his first funding.
Houston Texans Adding Homegrown Cornerback: ‘Smooth Operator’
The Houston Texans are set to bring in local product and rookie cornerback Collin Wright in their latest roster adjustment. The post Houston Texans Adding Homegrown Cornerback: ‘Smooth Operator’ appeared first on HEAVY.
UFC 333 Embedded, Episode 1: 'I just take their zeros'
The first episode of UFC 333 Embedded was released on Monday.
Here's how Central District Health plans to spend over $200k on the Treasure Valley's growing rat population
Former 49ers WR Reuniting with Aaron Rodgers and Steelers
On Monday, October 19, while the San Francisco 49ers are taking on the Washington Commanders in Monday Night Football, former wide receiver Marquez Valdes-Scantling has found a new home in the NFL, and it’s a reunion with a QB he is very familiar with, Aaron Rodgers, and the Pittsburgh Steelers, according to multiple reports. Valdes-Scantling […] The post Former 49ers WR Reuniting with Aaron Rodgers and Steelers appeared first on HEAVY.
Aaron Boone Gets Terrible Update For Long-Term Yankees Future
The New York Yankees upset many fans by bringing back Aaron Boone as manager for next season. Most fans were already aware, but an official report confirmed today Boone will continue his MLB managing career in New York. Another disappointing early playoff exit for the Yankees has fans questioning if the team has any chance […] The post Aaron Boone Gets Terrible Update For Long-Term Yankees Future appeared first on HEAVY.
Luke Bryan’s son undergoes surgery after high school football game injury: ‘Dang collarbone’
The “One Margarita” singer has two teenage sons with wife Caroline.
Oracle and AstraZeneca Partner to Advance AI-enabled Healthcare Innovation
Oracle today announced an agreement with AstraZeneca to explore how AI and real-world data can help clinicians identify eligible patients for clinical trials, accelerate evidence generation, and bring relevant research insights into everyday care. The collaboration is expected to combine AstraZeneca's scientific and therapeutic expertise with Oracle's health data, cloud, AI, analytics, and clinical workflow capabilities.
Manchester City vs AEK Athens – Predicted lineup and team news
Manchester City are expected to rotate against AEK Athens on Tuesday, with Erling Haaland likely to be rested and Antoine Semenyo out for around eight weeks.City lost 4-2 at home to Paris Saint-Germai...
Jayden Daniels passes for 300 yards on Monday night
Jayden Daniels did little as a runner in Week 6, but he did pass for 300 yards and a pair of TDs against the 49ers.
WATCH: Jupiter defeats Palm Beach Central in key district clash
Jupiter took down Palm Beach Central in an important district game, continued from Friday's lightning suspension. The Warriors now control their district destiny.
ALCS MVP Peralta Returning to Face Brewers in World Series
It has been less than a year since the Milwaukee Brewers traded Freddy Peralta. Now, he is going to face them in the World Series.
Bruins Nikita Zadorov Felt “Disgusted” By Being Scratched
Boston Bruins head coach Marco Sturm decided to send a message of tough love to bruising defenseman Nikita Zadorov when he designated him as a healthy scratch for their recent outing, a 4-1 victory on the road over the struggling Los Angeles Kings.Zadorov had been whistled for a penalty in their previous game against the […] The post Bruins Nikita Zadorov Felt “Disgusted” By Being Scratched appeared first on HEAVY.
Brandon McManus, Matt Prater to work out for Rams
Free-agent placekickers Brandon McManus and Matt Prater will work out for the Los Angeles Rams on Tuesday
Jaxon Smith-Njigba is dominating the NFL receiving race
Seattle Seahawks receiver Jaxon Smith-Njigba is dominating the NFL with a massive lead in total receiving yards.
In Massachusetts, 6 rural hospitals could get upgrades as $162 million health fund opens
Each hospital can request up to $2.5 million.
Jalen Hurts' Blood Clot Diagnosis: Revisiting Deion Sanders' Health Journey
With Jalen Hurts sidelined by pulmonary blood clots, Deion Sanders’ grueling history of surgeries and hospitalizations offers a sobering roadmap for the Eagles quarterback’s high-stakes recovery process.
Ryan Reaves Pulls Curtain Back On Time With Maple Leafs
Former Toronto Maple Leafs enforcer Ryan Reaves announced his retirement from the NHL last month, ending his career that spanned 16 total season and multiple clubs, including a stop with the Maple Leafs.Reaves, who accumulated over 1,000 penalty minutes during his career, is now pulling the curtain back on his time while with the Maple […] The post Ryan Reaves Pulls Curtain Back On Time With Maple Leafs appeared first on HEAVY.
Seminoles Mourn the Passing of Former Coach Chuck Amato
He was a fixture on the Florida State sideline for 27 years, and coached many of the program's greatest defensive stars, like Derrick Brooks and Corey Simon. to name a few.
Rays Clinch Pennant, Head to Small-Market World Series
The Rays clinched their third American League pennant.
Jessica Lange ranks her “American Horror Story” characters: ‘I loved the whole world we created’
In “AHS: 13,” the actress reprises all four: Constance Langdon, Elsa Mars, Sister Jude Martin, and Fiona Goode.
Timberwolves Add a Year to Jaden McDaniels’ Contract
The Minnesota Timberwolves took care of some contract business with Jaden McDaniels two days before opening night.
Bears Receive New Trade Take on Colts DT DeForest Buckner
Harrison Graham of Chat Sports believe the Bears should look to make a trade for Colts defensive tackle DeForest Buckner. The post Bears Receive New Trade Take on Colts DT DeForest Buckner appeared first on HEAVY.
Steelers set to reunite with former wide receiver
The Los Angeles Chargers released Valdes-Scantling on Saturday.
The 2026 South Carolina Political Beat Candidate Guide: York County
The 2026 South Carolina Political Beat Candidate Primary Guide: York County
Scientists found 2 ways to destroy 'forever chemicals,' and 'forever' may not mean forever
The video says PFAS "barely break down in nature" and can remain for decades or even centuries.
Lions PFF Rankings: Detroit's 5 Highest-Graded Offensive Stars
The Lions are coming off their bye week with several offensive stars playing at an elite level. From Penei Sewell’s dominance to Jahmyr Gibbs’ explosive production, here are Detroit’s top five PFF-graded players.
Lakers Depth Chart For Final Roster After Dalton Knecht Release
T he news of the Los Angeles Lakers releasing Dalton Knecht confirms the final roster entering the NBA regular season. Bronny James and Jaden Hardy survived the cut and will make the roster to keep their jobs. Knecht was not expected to get strong playing time, but he removes a player who could give the […] The post Lakers Depth Chart For Final Roster After Dalton Knecht Release appeared first on HEAVY.
Monday practice report for Bears
Bears have T.J. Edwards, Kyle Monangai among players listed on Monday's estimated practice report
JD Vance declines to endorse Netanyahu for reelection, says he's focusing on midterms
Vice President JD Vance declined Monday to endorse Israeli President Benjamin Netanyahu for reelection a day after President Donald Trump endorsed the embattled Israeli leader.“The president has the m...
Dan Lanning addresses Evan Stewart arrest, punishment
Oregon Ducks football coach Dan Lanning addressed the arrest of WR Evan Stewart on Monday night during his weekly press conference.
Monday practice report for Patriots
Patriots have A.J. Brown, Drake Maye among players listed on Monday's estimated practice report
Utah Jazz Are Asking the Wrong Question About Ace Bailey
Forget the ceremonial opening tip. Utah must decide if their versatile rookie thrives in high-pressure closing lineups where meaningful possessions define growth and dictate the game’s outcome.
Things to do: These are the best entertainment events in Brevard for Oct. 16-22
Find your weekend adventure! Film festival, Oktoberfest and Reggae top our list of Brevard's best entertainment events.
Suns Learned Some Important Lessons Before Games Start Counting
From Jalen Green’s potential stardom to lingering turnover troubles, discover which tactical adjustments and roster developments will define Phoenix’s pursuit of a title this regular season.
Every Partizan player drafted by the Golden State Warriors
Let's take a look at every player who has been drafted by the Warriors out of Partizan.
Wolves give Jaden McDaniels a $40 million contract extension
How many years are on the extension? One. And it sets the stage for an even bigger payday if he continues to ascend.
Generous paternal leave policies improve maternal and newborn health, family finances and workplace equality
Paternity leave benefits extend beyond dads, supporting maternal recovery, child health, family finances and a more equitable workplace.
Three Free Agent Relievers Who Could Fix Tigers’ Bullpen
The free agent relievers class is both strong and deep this off-season. That's great news for a Detroit Tigers team that struggled in high-leverage situations late in games, blowing 68 leads en route to a disappointing fourth-place finish in the American League Central. Those 68 blown leads are both a franchise and Major League Baseball …
Bulls Center Nic Claxton Gets Updated Hamstring Injury Timeline
Chicago's frontcourt depth will be tested early without their 6-foot-11 big man.
Are the Houston Texans Finally Back?
After dropping their first four games, Houston has responded with back-to-back wins.
Reid Defends Kicker Who’s Still Taking Away Points
Kansas City Chiefs kicker Harrison Butker missed two kicks on Sunday, but Andy Reid doesn't sound concerned.
Jaden McDaniels, Timberwolves reportedly agree to $40M extension
The deal keeps McDaniels under contract through the 2029-30 season.
McDaniels strategically secures an additional $40 …
McDaniels strategically secures an additional $40 …
Panthers Land Just Outside Top-10 of NFL Power Rankings
The Carolina Panthers got another win over the weekend against the Philadelphia Eagles.
Jalen Hurts’ Health Scare Puts NFL’s Relentless Expectations Into Perspective
Six days ago, the conversation surrounding Jalen Hurts was about football. His $255 million contract, Philadelphia's offensive struggles, and whether he was playing well enough to justify the enormous expectations that come with being a franchise quarterback. Those were fair questions. They still are, at least from a football standpoint. But Monday's news that Hurts …
Jalen Hurts’ Health Scare Puts NFL’s Relentless Expectations Into Perspective
Six days ago, the conversation surrounding Jalen Hurts was about football. His $255 million contract, Philadelphia's offensive struggles, and whether he was playing well enough to justify the enormous expectations that come with being a franchise quarterback. Those were fair questions. They still are, at least from a football standpoint. But Monday's news that Hurts …
Broncos vs. Cardinals odds: Opening lines for Week 7 matchup
The Denver Broncos are road favorites over the Arizona Cardinals in Week 7. No overdogs this week!
Political hate speech can have real-word fallout. After the alleged attack on Helen Haines, our leaders must act
Social media amplify the worst excesses of what passes for public discourse, while some media outlets foment polarisation
KaVontae Turpin unlikely to play in Week 7
Dallas Cowboys wide receiver/kick returner KaVontae Turpin appears unlikely to play in Week 7 against the Philadelphia Eagles
76ers' Most Important Duo Might Not Be Who Everyone Thinks
While the Philadelphia 76ers built their roster to support Joel Embiid with LeBron James and Jaylen Brown, the two young guards are the key to victory.
Actor, activist Jane Fonda makes appearances, endorsements in Oregon
Actor and progressive activist Jane Fonda made appearances in Salem and Portland to support Oregon Democratic candidates for the November election.
Ex-Dallas Cowboys 1st-Round Draft Bust Signs With Packers
Ex-Dallas Cowboys first-round draft bust signs with Green Bay Packers. The post Ex-Dallas Cowboys 1st-Round Draft Bust Signs With Packers appeared first on HEAVY.
NFL Draft stock report- strong sell: Bryce Underwood, QB, Michigan
Rated the number one overall recruit, regardless of position, in the high school class of 2025, expectations were sky high for Bryce Underwood.
Vandals hit NYC subway OMNY readers in apparent political protest
NEW YORK — Cops are looking for a group of vandals who took a drill to a bank of One Metro New York, or OMNY, readers at a Brooklyn subway station, apparently as a political protest. The subway sabota...
Hopeful DeMarvion Overshown can return in Week 7
Dallas Cowboys linebacker DeMarvion Overshown might be able to return in Week 7 against the Philadelphia Eagles
Spurs Roster: Carter Bryant Makes Strong Case for Bigger Role
Carter Bryant is making a case to be a normal rotational player on the Spurs roster. Against the Suns on October 14th, he had 16 points and hit four threes. With improved shooting and improved defense, his case for a lot more playing time is strong. The question becomes whether or not he can stay […] The post Spurs Roster: Carter Bryant Makes Strong Case for Bigger Role appeared first on HEAVY.
Couple embezzled millions from large Portland business to fund trips to Vegas and Legoland, lawsuit says
PORTLAND, Ore. (KOIN) — One of Portland’s largest employers has filed a lawsuit against one of its workers. Daimler Trucks North America is seeking more than $6.5 million in damages from Terry Watson,...