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Scientists uncover the hidden survival trick that lets cancer bounce back
Scientists discovered that certain cancer cells use a low-level activation of a DNA-dismantling enzyme—normally seen in cell death—to survive treatment. Instead of dying, these “persister cells” leverage this sublethal signal to regrow. Because the mechanism is non-genetic, it appears much earlier than typical resistance mutations. Targeting this enzyme could help stop tumors from returning.
Massachusetts is seeing more people drop health insurance
“In the first month of open enrollment, we’ve seen over 10,000 people terminate their coverage for 2026," says Audrey Morse Gasteier, Health Connector Executive Director.
VSCO lays off 24 staff as its consumer business suffers
In an internal memo seen by TechCrunch, VSCO's CEO Eric Wittman said the company's consumer business had declined more than expected, and some of its new growth initiatives didn't yield the expected results.
Pebble's founder introduces a $75 AI smart ring for recording brief notes with a press of a button
After rebooting the Pebble smartwatch, founder Eric Migicovsky is expanding his company's device lineup with a new smart wearable: an AI-powered smart ring known as Index 01. Named for the finger where the ring is meant to be worn, the new $75 ring is not meant to be a competitor to the always-on, always-listening AI devices, like the AI pendant Friend, but instead offers a way to record quick notes and reminders with a press of a button on the ring's side. AI only comes into play via the open source, speech-to-text, and AI models that run locally on your smartphone, via the open source Pebble mobile app. That is, if the Ring's button is not being pressed, it's not recording. (And this is a press-and-hold gesture, too, which means you can't start the ring's recording and then let go to surreptitiously record a conversation.) You can wear the stainless steel ring while in the shower, washing hands, doing dishes, or in the rain, but you would have to take it off for other water-related activities, like swimming. At launch, it's water-resistant to 1 meter. The ring is also not a fitness tracker or sleep monitor. It doesn't record details about your heart rate or health. And it's not there to be your AI friend. "I'm not trying to build some AI assistant thing," Migicovsky told TechCrunch in an interview. "I build things that solve one main problem, and they solve it really well," he explains. "I think of as external memory for my brain...that's what this is. It's always with you." Plus, the ring has been designed to be highly reliable and privacy-preserving, he says, as all your thoughts are stored on your phone, not in the cloud. There is no subscription. Migicovsky has been wearing the ring for three months now and says he cannot imagine going back to a world where he doesn't always have a memory device with him. "The problem is that, during the day, I get ideas or I remember something, and if I don't write it down that second, I forget it," he says. The ring solves this problem, he adds, without becoming another device you need to charge. "The battery lasts for years," Migicovsky claims. Technically, the ring is said to support roughly 12 to 14 hours of recording. On average, the founder says he uses it 10-20 times per day to record 3-6 second thoughts. At that rate, he'll get about two years of usage. When the ring's battery dies, you can ship it back to the company for recycling. When using Index, you can record up to five minutes of audio, which can be saved to the ring and synced to your phone later. This makes sense for recording briefer, personal thoughts and notes, even when you don't have your phone handy, but it wouldn't work for recording a longer chat, like a presentation, meeting, or in-person interview of some kind. The ring also supports 99+ languages and has a bit of on-device memory, in case you're not in Bluetooth range of your device, where the recording is ultimately saved and transcribed. (The raw audio is retained, too, in case the speech-to-text is garbled due to loud background noise). If you own a Pebble smartwatch or one from another brand, your recorded thought can even appear on the watch's screen so you can verify it's correct. The ring works with Pebble's mobile app, which offers notes and reminders, but can optionally integrate with your phone's calendaring system, too, or other apps, like Notion. And the ring's software is open source, which makes it hackable by the community, the founder points out. Because of its open nature, the ring's button is already programmable. In addition to the press-and-hold gesture, you can program the ring to do other things with a single or double press, like play or pause your music or control the shutter on your phone's camera. You could use it to send a message through the universal chat app Beeper, which Migicovsky also created, or you could add your own voice actions via MCP. A new approach to hardware Migicovsky acknowledges that hardware can be difficult to get right -- as the previous exit of Pebble to Fitbit showed. (Fitbit, too, was later acquired by Google in 2021). "I didn't earn any money during Pebble -- we exited, but it was not a great exit," Migicovsky admits. This year, however, he decided to reboot the Pebble project after Google open sourced the PebbleOS, which opened up the door to new hardware. With his new company, Core Devices, Migicovsky plans to do things differently. Still, the founder doesn't regret his previous choices, he clarifies. "I wouldn't have gone back and changed anything. I loved what we built. I loved what we did. I love the company that we built, but it's not the only way to build a company," he told TechCrunch. " And, speaking as an ex-YC partner, there are -- there's a time and a place for building a venture-backed startup. Some companies are phenomenal when they raise money and build a big team, and I tried that...I think what I'm doing now is trying an alternative path, which is start from profitability," he says. The new company is a small team of five, self-funded, and focused on sustainability. So far, Core Devices has shipped the Pebble 2 Duo smartwatch with a black-and-white display. Its first run sold out, and the company is now preparing to ship the upgraded version, the Pebble Time 2. The newer device, which has seen 25,000 pre-orders, is a stainless steel watch with a larger, color e-ink screen. As for the Index 01, the ring's pre-order offer ends in March 2026. After that, the price increases to $99. It currently comes in silver, polished gold, and matte black and works with iOS and Android devices. Customers can select from eight ring sizes and three colors.
Here's why the measles outbreak just took a dangerous new turn
Measles outbreaks seen in Utah and Arizona remain the biggest in the country.
Where you’ve seen Mel from ‘Tracker’ before
'Tracker' introduced a new character named Mel during season 3
Alarm grows in Europe over what is seen as Trump's 'betrayal' of Ukraine
European governments are fearful that Washington is laying the groundwork for an ultimatum to Kyiv on Moscow's terms.
32 Pictures That ALWAYS Make Me Laugh Uncontrollably No Matter How Many Times I've Seen Them, Like, They're That Good
You gotta check these out.
COLLEGE and computer science among most enrolled 2025 fall course
The most enrolled courses largely consist of computer science offerings, along with other STEM classes and core requirements.
Lawmaker briefed on double-tap strike: ‘One of the most troubling things I’ve seen’
‘One of the most troubling things I’ve seen’: lawmakers briefed on double-tap strike
Two top House lawmakers emerged divided along party lines after a private briefing with the military official who oversaw September’s attack on an alleged drug vessel that included a so-called double-tap strike that killed surviving crew members, with a top Democrat calling video of the incident that was shared as part of the briefing “one of the most troubling things” he has seen as a lawmaker.
The biggest entertainment and fashion moments of 2025, as seen in AP photos
For many, 2025 felt like a blur and that was true in the world of entertainment, which saw happy reunions, somber farewells and introductions to fresh voices and faces.
Giant rotating string of 14 galaxies is 'probably the largest spinning object' in the known universe
A giant rotating filament of the cosmic web may be the largest spinning structure ever seen, and could help reveal how galaxies form.
Scientists capture flu viruses surfing into human cells in real time
Scientists have captured a never-before-seen, high-resolution look at influenza’s stealthy invasion of human cells, revealing that the cells aren’t just helpless victims. Using a groundbreaking imaging technique, researchers discovered that our cells actually reach out and “grab” the virus as it searches for the perfect entry point, surfing along the membrane.
Congress pulls major college sports bill after bipartisan backlash: 'Not ready for prime time'
The move to pull the SCORE Act by GOP leaders two hours before it was slated for a final vote was seen as a sign it didn't had enough support to pass.
West Village business hit in possible arson attack as 6 suspects seen...
Mexico Political Risk Hits Peru Level as Sheinbaum Support Sags
Mexico’s political risk has crept up to levels seen in Peru, as Mexicans voice mounting frustration over cartel-fueled crime, corruption and a stagnant economy.
You can get an LG B5 OLED for less than $900
We haven’t seen a better OLED deal during Cyber Monday
Seen but not forgotten: How citizen science helps document biodiversity in remote Borneo villages
When I, Erik Meijaard, worked as a wildlife consultant for a timber concession in Borneo, I often chatted with the logging truck drivers—and quickly realized that some of them knew far more about local ...
Too much focus on national issues has left TN suffering
Too many Tennesseans get outraged over national controversies while ignoring the local issues that impact their daily lives.
The Streaming Wars: How Audiences Are Changing the Entertainment Industry
The entertainment industry has always evolved alongside technology, but never at the pace we have seen over the past decade. The rise of streaming services has completely transformed how audiences consume film and television. Viewers have gone from waiting for scheduled programming to having instant access to thousands of shows and movies at any time. […]
How Recent Changes Are Shaping the Story Behind Beauty Health's Valuation
Beauty Health stock has recently seen its price target adjusted, with the fair value estimate holding steady at $1.93 despite some shifts in underlying assumptions. The primary driver behind this update is a lowered discount rate, which reflects analysts' increased confidence in management's ability to reduce risk and reinforce revenue stability. Stay tuned to learn how you can follow new developments and better understand the evolving narrative behind Beauty Health's valuation. Analyst Price...
Rising levels of hate forcing women out of Swedish public life, says equality agency
Country seen as champion of equal rights faces reckoning after senior politician says she felt compelled to quit
Hundreds of flights have been canceled after a snowstorm struck on one of the busiest travel weekends of the year
Chicago's O'Hare International Airport has seen the most cancelations, which came at the height of the Thanksgiving travel season.
Big tech's big spending in politics
Humanity has never seen anything like artificial intelligence. This new transformation technology is already changing the economy, And as Big Tech pushes for Super AI there are many calling for government oversight, regulation and protections for workers and the environment. But Big Tech is also spending big on politics to lobby so that its growth will remain unchecked.
Seen but not forgotten: How citizen science helps document biodiversity in remote Borneo villages
In Borneo’s remote villages, locals earn money by recording wildlife — reshaping conservation and redefining how communities value their forests.