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Heastie brushes off growing DSA influence, defeat of incumbents in Albany
Heastie sought to put the results into context while speaking with reporters at an unrelated event in Schenectady on Thursday.
Moore links Maryland primary to Mamdani-backed wins; analysts disagree
Gov. Wes Moore says Maryland’s primary election showed voters rejected the status quo, but political analysts say the results reflect a more complicated picture.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Roundup: Shift in NIL / BlackBerry transitions / Agriculture aid
More inclusive: A recent NCAA rule change is shifting name, image and likeness opportunities away from only the biggest star athletes to a wider range of student-athletes. The update gives schools more structured involvement in managing and facilitating NIL deals, which reduces some of the previous free-for-all environment. As a result, athletes who are not […]
South Dakota mayoral candidates separated by just two votes in shockingly close race, recount expected
The Sioux Falls mayoral runoff contest shockingly resulted in just a two-vote margin separating the candidates out of more than 36,000 ballots cast.
Gov. Shapiro on Mamdani-backed wins in NYC: Candidates doing ‘performative politics’ must learn ‘how to deliver results’
David P. O'Brien
About five years ago, David P. O'Brien had a comfortable position at Marsh & McLennan Cos., where he held the top post at the financial giant's Louisville, Ky., office. Despite the lofty rank, Mr. O'Brien found himself longing to be at a smaller company that had to work a little harder to land business. That desire led him away from Kentucky five years ago and to Cleveland, where he serves as executive vice president at business insurance agency Oswald Cos. "I left Marsh before it was en vogue," he said, referring to layoffs and defections at Marsh over the course of this year that followed accusations of bid rigging at the big firm. Above all, Mr. O'Brien, 38, wanted to work at a company that relied on its inventiveness, rather than its name, for business. He said he has found that at Oswald. "It causes you to be more creative, to be more resourceful," Mr. O'Brien said. For instance, an Oswald client seeking to do business internationally might be directed to the network of offices abroad run by competitors such as Marsh and Aon Risk Services Inc. "We're going to use whatever access into the market that makes the most sense for our clients," he said. Of course, using such a strategy can be dangerous for Oswald if its client decides to further a business relationship with one of the firms Oswald recommended. "That's the obvious question and why it's nontraditional," he said. "I think if we're good, and if we're bringing value to the client, then there's no risk. I'm not threatened by it." Imaginative business solutions of that type made his career move to Oswald from Marsh worthwhile. "It's very much a challenge," he said. "It helps you keep your edge. I'm all for the competition." John Jacunski, currently vice president and corporate controller at York, Pa., paper company PH Gladfelter Co., met Mr. O'Brien four years ago when Mr. Jacunski was at WCI Steel Inc. in Warren. So impressed was he with Mr. O'Brien's work for WCI that Mr. Jacunski has retained the Oswald executive at PH Gladfelter. "He's a young guy for the position he has, but he's done a great job for us," Mr. Jacunski said. Among his roles at Oswald, Mr. O'Brien leads the firm's client retention efforts and also serves as director of its property and casualty group. "You don't have the same human resources," he said of the job jump to Oswald. "You don't have, obviously, the safety net a big company has." But sometimes, it can be difficult to ascertain individual contributions when working at a big company. "I wanted to be able to see the end results of my work and my efforts," Mr. O'Brien said.
How should European scientists respond to the US AI kill switch?
Earlier in June, Europe’s worst fears of technological dependence were confirmed when the White House ordered the AI firm Anthropic to stop non-US citizens using its leading models. This kill-switch moment crystalised anxieties in Brussels that the continent, lagging the US on the creation of leading-edge AI models, is now a technological of vassal of Washington. The shock has specific implications for European scientists and universities. Some governments are now worried that with AI being integrated into labs, Donald Trump now has his finger hovering over an off switch for European science. “Having restrictions on this tool, it can have an impact on our own research,” said France’s research minister, Philippe Baptiste, at the VivaTech conference in Paris on June 18.Baptiste, himself a former academic, said that colleagues in mathematics had recently warned him they were now cut off from leading-edge US models, risking their work. “This model is not available anymore now because of the US restriction, and for the first time this had an impact on mathematics,” a field where large language models (LLMs) are making a significant contribution, said Baptiste. So, should European scientists avoid relying on US models in the future? Or would this be a self-harming overreaction? And how is AI being used in science, anyway? What happened?On June 12, it emerged that Washington, citing cybersecurity concerns, had ordered Anthropic to stop non-US citizens using two models: Claude Mythos 5, and Claude Fable 5, a version of Mythos but with guardrails to prevent abuse. Anthropic said Washington’s concerns were overblown. But forced to follow the order, yet with no way to check who was using the models, the company suddenly shut down access for everyone, US citizens included. There’s still no agreement on how to restore broad access. But last week, Bloomberg reported that select US companies, and the US government, still had access to Mythos despite the ban, but the EU’s cybersecurity agency Enisa had been shut out. Class division of researchersIn the longer term, access outside the US should be restored, said Marcel Salathé, co-director of the AI centre at the Federal Polytechnic School of Lausanne (EPFL), because a permanent restriction would be financially ruinous to US AI firms. “Even Trump will eventually budge to economic pressure,” he said.However, US AI firms might end up operating rather like banks, doing due diligence on users of their leading-edge AI models, he went on.European scientists are unlikely to fall foul of such checks, he said. But having a Chinese postgraduate in their lab, or doing a type of research the US disapproved of, could potentially result in access being denied. “It will create a sort of class division of researchers,” he said. More than frontier modelsHowever, successfully deploying AI in science is about far more than just having access to leading LLMs such as Mythos.Instead, many science-specific tools, most famously Alphafold, which predicts protein folding structures, require “far less” computing power to train than frontier models, well within the capabilities of European supercomputers, according to a recent analysis by the Arq Foundation, a Brussel-based AI think tank. Instead, tools such as Alphafold are possible because certain fields, like protein folding, weather prediction or astronomy, have large, clean, standardised datasets that can be used to train predictive models. Rather than compute, “data is the central constraint for AI for science,” the report says. For example, a less powerful physics model trained on CERN’s data “will be more valuable than the best model without certain data,” said Bengüsu Özcan, author of the report. European advantage?Europe could therefore steal a march by using its scientific data and infrastructure to create models US digital giants cannot. “They might actually match or go even beyond what these big [US] companies are doing,” said Özcan.Indeed, some European start-ups hope to create automated testing labs to create the kind of standardised data that could speed up the discovery of new materials. Materials scientists say there’s currently too little data to train models. AI scientistsHowever, even if the bottleneck for AI in science is often data, rather than compute, being at the mercy of the US for LLM access could still become a problem for European scientists. A new class of “AI scientists” based on leading LLMs is also emerging, Özcan’s report says.Unlike domain-specific tools like Alphafold, these try to automate day-to-day scientific work, by providing an overarching tool that coordinates specific models to synthesise existing literature, generate hypotheses or run analysis of data. The problem for Europe, however, is that these tools are sometimes based on US leading models. Google Deepmind’s AI Co-Scientist, for example, is built on Google’s Gemini LLM. Systematic failureThese scientific automation tools are still in their early stages, and still exhibit “systematic failures on scientific tasks,” Özcan’s report says. One of the problems is that the messy, day-to-day process of scientific discovery is largely not documented, meaning LLMs don’t have a good source of data to learn how scientists actually work. Meanwhile, some tasks, such as literature synthesis, don’t typically require access to leading edge models.However, the performance of AI scientific assistants could improve as companies such as Google pour resources into developing them. Rely on US“Unfortunately, for scientific assistants, there is not much we can do right now except rely on US frontier AI,” said Antoine Bosselut, a natural language processing expert based at EPFL. Chinese-built open models, which can run on local computers, lessening the risk of a shutdown, are touted as one alternative to US dependence. There’s also Mistral, once seen as Europe’s main AI hope, but the Paris-based company has seen its recent models fall behind in performance. But the Chinese alternatives are generally not as capable as US frontier AI models, said Bosselut, unless paired with fiddly, custom tools that allows them to act as independent agents. “Most scientists do not have the time,” he said. Don’t jump ship yetAlthough the kill switch moment is seen a warning shot for European scientists, it doesn’t mean labs should abandon US AI tools immediately. “I do not think the right response is simply to abandon US-based models and systems under the banner of sovereignty or independence,” said Mattias Björnmalm, secretary general of the Cesaer university association. “That would be an overreaction.”Related articlesEuropean sovereignty in AI requires ‘ugly trade-offs,’ say experts Robotic lab start-up makes case for €500M EU-funded materials testing facilityAI in science: is it useful? Instead, European researchers need to ask themselves whether they’re becoming dependent on technology that could be turned off in Washington, said Özcan. “They might not see this today, but they should really start asking this question,” she said. European researchers need a plan B, said Salathé. “I would recommend to every researcher, very proactively explore alternatives.”Own toolsIn addition, Björnmalm and others want European research institutions to develop their own scientific AI tools.Instead of signing AI deals with US digital giants, European universities should be using this money to create their own models, which may end up being superior for research, said Sabine Leonelli, an expert on the use of AI in science at the Technical University of Munich. “Universities in Europe seem to be happy to sign commercial contracts with US companies on the assumption [their AI tools] are better,” she said. But US frontier LLMs are typically opaque, and have been developed without independent scientific input, she said. “This is not good enough for science.”Last year, Swiss researchers released Apertus, an LLM designed to be completely transparent, from its development methods to its training data. The idea is that this makes scientific tools built on top of the model far more reproducible than with closed, commercial alternatives.“Europe needs more of this: serious capacity-building that gives researchers, universities and companies credible options,” said Björnmalm.
BlackBerry Sees New AI Opportunities as Embedded-Software Business Accelerates
BlackBerry lifted its fiscal 2027 outlook on higher first-quarter results, driven by embedded-software growth and expanding opportunities with artificial intelligence.
Mamdani's sweep in New York a 'political earthquake' among Democrats
New York City Mayor Zohran Mamdani scored a massive political victory on Tuesday when his trio of insurgent congressional candidates toppled two incumbents and the establishment favorite in an open seat, results some described as "a political earthquake" for Democrats.
Political insiders break down New York's 2026 primary election results
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Family towing business forced to start from scratch after theft
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How Brexit broke British politics
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Steam Machine Sells Out in Japan Despite Woeful Pricing
As was the case with the Steam Deck, Valve is selling the Steam Machine via Komodo Station, an Asian reseller that serves much of South-East Asia, and as a result, it skips the reservation and lottery system that is currently in place on Valve's own Steam Store. While this doesn't combat issues like...
New York’s Warning for Democratic Leaders
They aren’t the dominant force in their hometown.
New York’s Warning for Democratic Leaders
They aren’t the dominant force in their hometown.
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All politics is local politics
In today’s edition of The Tea, Spilled by Morning Joe: Joe on the results of yesterday’s primaries, the fourth anniversary of Roe v. Wade being overturned, and more.
AHA’s refreshed Rural Health Services website features resources to strengthen results and long-term viability
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Survey finds 3 in 10 adults using social media, AI for health information and advice
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Are AI chatbots like ChatGPT politically biased? We tested them.
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Mamdani extends influence with clean sweep in N.Y., Trump hedges in South Carolina: The latest primary results
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Syracuse business owners speak out over I-81 construction disruptions
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FedEx posts strong earnings results in last quarter with freight business
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Hallmark Health Care Solutions launches AI solution to tackle workforce ‘black box’
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NASA’s Webb Pinpoints Millions of Stars Within Cigar Galaxy
M82's intense star formation, thought to be the result of a galaxy merger, will be a short-lived event in astronomical terms, which makes this a one-of-a-kind environment to study. M82 is also known as the Cigar galaxy, Messier 82, NGC 3034.
Build an AI Scientist for Life Science Discovery with NVIDIA BioNeMo Agent Toolkit
AI scientists are emerging as a new interface for scientific computing. These agents can read papers, write code, generate hypotheses, call APIs, inspect files, and iterate on results. But science isn’…
Atlanta Braves News: Tarik Skubal, Drake Baldwin, More
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Kansas City Royals News: Bobby Witt Jr working out
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Q1 Media & Entertainment Earnings: Sinclair (NASDAQ:SBGI) Impresses
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New tax rules for sports bettors, entrepreneurs and others proposed in NC
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Most innovative CMOs of 2026: power list
Business Insider's list of the most innovative CMOs spotlights marketers who are pushing brands into new territory and delivering measurable results.
Caitlin Clark, DeWanna Bonner altercation leads to five techs, ejection
The Fever's 86-77 win over the Mercury descended into chaos in the fourth quarter, resulting in five technicals and an ejection.
Caitlin Clark, DeWanna Bonner altercation leads to five techs, ejection
The Fever's 86-77 win over the Mercury descended into chaos in the fourth quarter, resulting in five technicals and an ejection.
iPhone 18 Pro camera upgrade 'confirmed' by another rumor
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Silicon Valley spent big in California's primary election. Did tech money influence the results?
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Judge blocks use of database to check citizenship in voting
The judge ruled that the system aggregated Americans' sensitive personal data in a way that could result in voters being wrongly purged from voter rolls
Judge blocks use of database to check citizenship in voting
The judge ruled that the system aggregated Americans' sensitive personal data in a way that could result in voters being wrongly purged from voter rolls
Populist wins Colombia election, but results are challenged
Conservative political outsider Abelardo de la Espriella held a razor-thin lead after Colombia’s deeply polarized presidential runoff, which is being challenged by the ruling party’s progressive candidate.
Trump threatens serious criminal penalties for those he says ‘vandalized’ the Reflecting Pool
President Donald Trump called Monday for those he accused of vandalizing the newly renovated, and now quickly deteriorating, Reflecting Pool on the National Mall to face serious criminal charges that could result in lengthy prison sentences.
Digital Health Tools Are Reshaping Healthcare in the United States
/PRNewswire/ -- At least 12 percent of Americans now communicate with their healthcare providers about appointments, test results, and ongoing treatments via...
iOS 27 adds brand new widgets for your iPhone’s Home Screen
iOS 27 adds a new, larger widget size and as a result comes with 15+ new widgets for your Home Screen, here’s the full list.
A common vitamin could help fight one of the deadliest brain cancers
A clinical trial is exploring whether high doses of vitamin B3 could give patients with glioblastoma a better chance against the aggressive brain cancer. Scientists found that niacin may help revive immune cells that tumors shut down, allowing them to attack cancer more effectively. Early results have been promising, with patients showing significantly better progression-free survival than expected.
Science Over Tradition: Plymouth South Middle Schoolers Advocate for Later School Start Times
PLYMOUTH - June 15, 2026 - In a powerful demonstration of student advocacy, a delegation of eighth-grade students from Plymouth South Middle School presented compelling, science-based research to the School Committee, urging district leadership to push back school start times to improve adolescent mental health, well-being, and academic performance. The presentation sparked immediate commitment from the administration to formally evaluate the district’s schedule over the coming school year. Subscribe The Full Story The final in-person meeting of the academic year opened with a celebratory outdoor ceremony honoring dozens of elementary, middle, and high school student artists whose work was chosen for the biannual Central Office Artwork Awards. However, the evening’s primary policy focus quickly shifted to student-led civic action when eighth graders Sophia Scarini, Skye Togun, Leah Mansfield, James Moore, Avery Mahan and Lily Simpson took the podium. The students revealed that their presentation was the culmination of a year-long civics project involving local community assessments, interviews with former officials, and extensive literary analysis. The research sharply highlighted the biological mismatch between adolescent sleep patterns and current school schedules. Under the district’s current framework, Plymouth High Schools open at 7:20 a.m., Middle Schools at 8:12 a.m., and Elementary Schools at 9:05 a.m.. “The high school start times directly contradict students’ natural sleep patterns,” student Leah Mansfield explained, noting that the teenage brain does not naturally produce melatonin until around 11:00 p.m.. The student presentation underscored a harrowing correlation between sleep deprivation and severe mental health struggles, citing data that adolescents with insomnia are ten times more likely to develop depression. Conversely, data shows that just one additional hour of sleep results in a 28% reduction in students reporting feelings of depression or sadness.
The Siege of Death Mire begins: Submit your results
Help to decide the fate of a key Armageddon hive.
Talk Business & Politics: AR Sec. of Education Jacob Oliva, Rep. Aaron Pilkington
The results are in concerning Arkansas student progress in the Atlas testing program.
Fantasy Baseball 2026: Winners and Losers From Week 12
The Pittsburgh Pirates lost a game in Colorado because of a cleat. The cleat of pinch-runner Billy Cook grazed third baseman Kyle Karros’s glove on a slow ground ball that would have otherwise tied the game. The call gave Paul Skenes a loss instead of a no-decision and surely fantasy baseball results were harmed by the call, which was the actual correct call.
A Big Change Is Coming to Roku TVs
A big transformations are underway across the Roku TVs home screen as leading manufacturers, including TCL, begin implementing standardized home screen interfaces on their devices. This shift replaces the previous customized designs that each brand had developed independently with the uniform Roku platform experience. The result is a more consistent visual presentation that emphasizes the […]
The Politics of Climate Possibility
Americans are far more likely to engage on climate change when they believe governments can deliver meaningful results.
How Trump’s Fragile Agreement With Iran Is Shaping the Midterms
Democrats say the president started an economically painful war that resulted in nothing positive. Republicans are more divided, even as they show some signs of relief at falling gas prices.
Cape Verde XI vs Uruguay – Predicted lineup and team news
Cape Verde arrive at Miami Stadium on Sunday looking to build on one of the most celebrated results in their nation’s sporting history.The Blue Sharks produced a disciplined, resolute defensive disp...
Chasing life goals is a recipe for disaster – so try these tiny experiments instead
Whether its our careers, health or relationships, we often set the bar too high and end up feeling disappointed when it doesn’t work out. Try this new way of thinking … and you may just see some real results
UFC Vegas 119: Kape vs. Horiguchi live results
The UFC octagon is back in Las Vegas for UFC Fight Night 279 at the Meta Apex. A flyweight rematch between former RIZIN Bantamweight Champion Manel Kape and former UFC flyweight championship challenger Kyoji Horiguchi headlines the fight card. Follow along for the live ...
Healthcare Has Been the Job Engine. That’s About to Change.
Federal healthcare cutbacks, including Medicaid funds, are expected to result in hundreds of thousands of fewer jobs.
2026 World Cup: USA Win Over AUS 'Good For America' But 'Bad For Books'
One of the most-bet soccer games in American history resulted in some pain for sportsbooks. Patrick Everson breaks it down.
Ozempic changed obesity treatment, but experts say the real revolution is next
The obesity treatment landscape is changing fast, with GLP-1 drugs opening the door to more effective care than ever before. Experts now envision a future where medications, minimally invasive procedures, surgery, and precision medicine work together to deliver better long-term results.
AI Is Replacing Sustainability As The Latest Business Trend
The decline of sustainability reporting has impacted the sustainability and business industries, resulting in a shift in focus to AI
Ebola in DR Congo: Six-year-old 'doing well' after armed men took her from hospital
Health facilities have come under attack during the current outbreak as a result of misinformation and fear.
Researchers found a Wordle strategy that wins 99% of the time
Researchers developed a Wordle-solving strategy that succeeds 99% of the time by focusing on information gain rather than likely answers. The method uses Shannon entropy to identify guesses that reveal the most about the hidden word. Each guess is designed to slash uncertainty and narrow the possibilities faster. The result significantly outperformed more traditional Wordle tactics.
Mercedes release statement on withdrawing Monaco podium appeal
Mercedes confirmed that it has withdrawn its Right of Review request concerning the penalties George Russell received and served during the Monaco Grand Prix, explaining the reasons behind its decision to drop the appeal. The team disclosed that it had initially explored every available avenue to mitigate the impact of Russell's pit lane speeding penalty on his final result, particularly after Pierre Gasly's time penalty was overturned.
U.K. Election Results Live Updates: Burnham Wins Makerfield By-Election, Clearing Path to Challenge Starmer
Andy Burnham, the Labour Party’s most popular politician, earned a decisive victory for a parliamentary seat in northern England. The win energizes his bid to become prime minister.
A brain-computer interface has, for the first time, restored fluent everyday speech to a person who had lost it — a man with ALS who had not spoken aloud in years until a small implant from the BrainGate clinical trial began translating his attempts to speak directly into computer-synthesised words, in a result researchers reported in June 2026
Casey Harrell can now talk for twelve hours at a stretch. Two years ago, he could not talk at all. The ALS he was diagnosed with several years earlier had progressively destroyed the motor neurons controlling the muscles of his face and throat, leaving him with the symptoms doctors call dysarthria and, eventually, anarthria — […]
Accenture Just Had Its Worst Day in Years. Is AI Coming for the Consulting Business?
The consulting giant posted solid results, yet a cautious outlook and a multibillion-dollar acquisition bet sent its stock to the lowest level in years.
Glover, Street Racer Collection getting free Nintendo Switch updates to add PS1 version
As announced by QUByte today, Glover and Street Racer Collection will both be receiving free updates on Nintendo Switch to add their PlayStation versions. The two will have their patches arrive in 2027. Glover on the PlayStation 1 came out after the N64 version. There were quite a few changes on PS1 because the hardware was less powerful. It resulted...
The Tricky Politics of Revenue
Our nation’s fiscal trajectory is unsustainable, in part due to the decline in revenue collection stemming from a series of tax cuts. Often enacted with bipartisan support, these tax cuts have severely damaged the linkage between economic growth and revenue flows to the U.S. Treasury. The result: Ev
The quiet end of identity politics
California’s primary election showed that voters are prioritizing competence, results, and accountability over identity politics, and that candidates of all backgrounds should be judged on th…
Amid Concern Over Xbox Studio 'Bloodbath,' New Report Says Developers Are Being 'Punished Today for Following Orders'
A new report suggests Xbox layoffs will likely result in a "bloodbath" of job losses and studio closures, leaving developers "punished" simply for following Microsoft's orders.
Accenture Reports Third-Quarter Fiscal 2026 Results
Accenture reported financial results for the third quarter of fiscal 2026 ended May 31, 2026.
'Dancing With the Stars' announces beloved late-night personality as newest competitor
'Dancing With the Stars' is dipping into the late-night pool for season 35, as the show announced this talk-show mainstay as the newest competitor to join Maura Higgins, Ciara Miller, and more.
Michelle Beadle Among Biggest Losers Of 2026 NBA Finals
Michelle Beadle has sounded like a pretty big sore loser following the conclusion of the 2026 NBA Finals. Beadle, a lifelong Spurs fan, was understandably disappointed by the result of the 2026 NBA Finals. The Spurs fell to the Knicks, 4-1, blowing big leads in nearly every loss. The future remains ...
Discovery Supercomputer’s first applications selected for Day-One Science
Scientific computing experts at the Department of Energy’s Oak Ridge National Laboratory have selected the first nine research projects that will run on Discovery, the nation’s next flagship supercomputer, slated for deployment in 2028. The projects will be developed through the Discovery Center for Accelerated Application Readiness program at ORNL’s Oak Ridge Leadership Computing Facility. The program is designed to ensure that a suite of leading-edge scientific applications is optimized and ready to deliver results as soon as Discovery becomes operational.
Georgia Republicans choose Collins for Senate and Jackson for governor, a mixed result for Trump
Georgia Republicans delivered a split decision for Donald Trump in Tuesday runoffs, opting for the president’s preferred U.S. Senate candidate but rejecting his choice for governor in favor of a billionaire first-time candidate who spent freely from his personal fortune to win the nomination.
When Health Results Raise Questions but Provide Few Answers
Older people are often treated as if their judgment is less valuable, creating the risk of a future where human intelligence is seen as something that depreciates with age.
Politics: Can Divides Over War Be Bridged At The G7 Summit?
This week, on the southern shores of Lake Geneva, leaders of the Group of Seven countries gathered for their annual summit.There are several pressing issues that require attention including the U.S. and Israeli war with Iran, the resulting economic crisis, the state of the Persian Gulf, and long term questions about the future of relations with Iran.The G7 meeting also notably brought Ukrainian President Volodymyr Zelenskyy face-to-face with President Donald Trump. Trump told reporters that the war Ukraine was not a priority for the United States, saying that his country had “nothing to do” with a war that was “thousands of miles away.”We discuss what this 2026 G7 meeting reveals about the state of the U.S. relationship with its most important allies, especially after months of a war of choice with Iran.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.
How LinkedIn helps marketers cut wasteful spend and improve roi
Discover how marketers use LinkedIn to improve ROI, reduce wasted spend, and drive measurable business results.
What scientists discovered about your kitchen sponge will alarm you - Futura-Sciences
The results show that kitchen sponges do release measurable amounts of microplastics over time. However, the researchers found that the biggest environmental burden linked to hand-washing dishes is not the plastic particles themselves. Instead, water use accounts for the vast majority of the overall impact. Kitchen sponges as a source...
Where do things stand in the DC primary races?
Janeese Lewis George is holding a large early lead in the Democratic mayoral primary in Washington, DC, based on initial election results, but CNN has not projected a winner yet.
Patriots survey results: Fans prefer to keep Kayshon Boutte
Patriots fans share their thoughts on Kayshon Boutte’s future.
Neshaminy named Bucks County high school baseball team of year
Third straight season in state baseball playoffs results in Neshaminy winning first PIAA championship
Latvia pilots citizen engagement in research grant evaluations
Latvia has introduced an element of citizen engagement to the evaluation of nationally funded research grants. The aim is to both create more connections between science and society, and to improve the quality of its evaluations. The move comes as research funders across Europe are experimenting with ways to improve evaluation processes in the face of a sharpened focus on science’s impact on society. Evaluators of grant applications submitted to Latvia’s Fundamental and Applied Research Programme (FLPP), the country’s main research funder, will this year have the option of consulting citizen feedback on challenges the public thinks science should focus on to inform their decisions. “In recent years, both public discussions and policy-level debates in Latvia have highlighted the importance of demonstrating how publicly funded research contributes to society, the economy and the resolution of real-world challenges,” said a source at the Latvian Council of Science (LCS), which manages the FLPP. “At the same time, research institutions themselves expressed interest in improving the project evaluation framework while continuing to ensure that funding is awarded to the highest-quality projects,” the source added. The citizen input comes from a survey that was conducted between 25 February and 16 March 2025, to which 1,737 people responded. It gathered information on what the public views as problem areas for Latvia, and the role of science and technology in providing solutions to these problems. A summary of these responses has been included as an annex to the FLPP 2026 call for proposals that evaluators can refer to, purely in an advisory manner, when judging proposals. Results from the survey show that the main problem areas identified by the public were in healthcare and public health, followed by the development of new treatment methods and medicines, and then digital technology, data security and cyber security. At the bottom of the list was research aimed at acquiring new knowledge about the universe, matter and the laws of nature. Further analysis looked at the public view of the possible role of science in solving these problems. The survey charted 4,167 individual responses based on open-ended questions that were derived from the participants’ answers. The analysis again found that medical and health sciences topped the scoring, with 788 responses referring to the field. Humanities and the arts were bottom of the list, with 625. Digging further into the details, the survey suggests citizens are aware of and concerned about a number of research areas. This includes technologies and innovation to improve the environment or reduce pollution, the development of modern military technologies and cybersecurity tools, and the development and application of artificial intelligence, among others. “We hope this initiative will help strengthen public trust in science and create a more meaningful dialogue between researchers and society,” the LCS source said, adding that it offers benefits to researchers, evaluators and to the general public. More space for citizen engagement in evaluationsThere is a gradual but increasing use of citizen engagement in research evaluation processes around Europe, especially in healthcare, but it remains relatively rare, said Henry Sauermann, a professor at the European School of Management and Technology in Berlin and an expert in citizen science.“Given that we are at a point where citizen involvement is extremely limited, there is presumably space for more, but it's not that we should do it just because we want to do it,” he told Science|Business. He said some research lends itself better to having citizen input, and this usually tends to be on the applied end of the science spectrum where the public can offer useful feedback based on their experiences. He added that advising scientists on certain topics to study is also a useful approach, in the way that Latvia is doing. “The public does fund a lot of science, there's a lot of tax money going into this. We of course do want to preserve academic freedom, but it's also not unreasonable to incorporate more feedback or input from citizens where possible,” he said. Related articlesCitizen science: where, when, and how to let the public contribute to researchHow can Europe cope with a flood of AI-assisted research grant proposals?Data Corner: Horizon Europe’s AI, digital and data call success rate is 5.2%There are several ways of involving citizens in science funding. The most minimal way is having a few representatives on a panel, such as members of a patient group or union. The most direct way is crowdsourcing funding for specific projects. There is an increasing number of online platforms that allow the public to chip in to support scientific proposals.Sauermann studied this in a recent paper and found that it can have its uses, but it still is not clear if there are benefits to it. There are various assumptions linked to citizen engagement, for example that it increases public trust in science, or that it provides a representative view of what the public thinks about science. These are not necessarily true, Sauermann found. People who participate in engagement activities tend to already be very trusting of science, and, on the whole, it is generally the well-off and well educated who contribute, giving a narrow view of public opinion. On whether citizen input can help manage the increasing number of proposals that are being submitted due to assistance from AI, Sauermann is more sceptical. “The obvious answer to the flood of AI-written proposals is AI-driven evaluation,” he said, adding that it doesn’t mean citizen engagement shouldn’t be a part of evaluations in a well thought-out manner. Southern Denmark’s successful approachOne successful example of citizen engagement in science evaluations was implemented in southern Denmark. Between 2019 and 2025, citizens in the region were invited to vote to fund one of five pre-selected projects in the field of healthcare. The project, called A Healthier Southern Denmark, was a collaboration between regional authorities, the University of Southern Denmark, and two media partners. Over the seven years, there were 75,000 votes and significant public engagement online and on social media. “It was a bit of a wild project, we’d never done something like that before and we were a bit nervous about what would be said in the media about it. But actually, people were very positive,” said Anne Kathrine Overgaard, one of the main organisers of the project from the University of Southern Denmark. The university and its researchers have learned a lot from the experience, particularly about engaging with society and shaping their research to match real-world needs. This is important with Europe’s increasing focus on competitiveness and bringing innovations to market faster, Overgaard said. She hopes to see more citizen engagement in evaluation processes and in science more broadly. “For many years, citizen engagement has been a bit of an add-on to proposals, just to check a box. But I think things are changing,” she said. It’s less about citizens just gathering data and more “about the dialogue between the public and the scientists,” she said. The initiative ended last year as the team wanted to regroup to find fresh momentum. The development of AI and AI-written proposals has made Overgaard reflect on how the project could be reworked to help evaluators. She hopes to bring it back in the future. “It could be a good idea to try this initiative again in a slightly re-worked format,” she said.
New plasma trick could unlock smaller, more powerful computer chips
A new technique could solve one of the biggest challenges in making future computer chips from ultrathin materials. Researchers found that coating molybdenum disulfide with oxygen or fluorine lets manufacturers remove just the top layer of atoms much more safely during plasma processing. The result is a cleaner, more controlled path toward smaller and more capable electronics.
Merchants of Doubt and the attacks on Extreme Event Attribution science
Last week, I attended a meeting at Columbia University on attribution science and climate law, hosted by the Sabin Center. It was a fantastic event, bringing together scientists and legal experts working at the intersection of extreme event attribution and climate law. Subscribe For those unfamiliar with it, extreme event attribution attempts to quantify the contribution of climate change to an extreme event. For example, several groups analyzed the impact of climate change on Hurricane Harvey’s enormous rainfall totals over Houston, Texas and they found that climate change increased rainfall by 15 to 38%. One thing that came up again and again was how terrified fossil-fuel interests are of extreme event attribution science. They are acutely aware that this research could land them in court. And losing those cases would leave them legally liable for billions of dollars in climate damages. Because the legal stakes are so high, the blowback has turned ugly. I spoke with several scientists at the meeting who are facing ongoing harassment over their work. This blowback is a coordinated campaign to make the entire field look suspect. The goal is to create the impression that attribution science is too uncertain, too political, or too conflicted to be useful in court or in public policy. The strategy is not based on actual science or evidence of misconduct, but on the generation of doubt. The new Merchants of Doubt We’ve seen this before. In fact, not that long ago: We only have to go back a year to the Department of Energy (DOE) Climate Working Group (CWG) report to see an example of using doubt as the tool to push back against well-established science. This strategy is laid out in an email from a member of the CWG, Dr. Roy Spencer, that was released during litigation over the Climate Working Group process. The key quote is: About all I can hope is that what we write will provide sufficient “reasonable scientific doubt” regarding the science claims in the 2009 TSD [technical support document], based upon almost 2 decades of new science, to call into question the original reasoning for the EPA Administrator’s decision that CO2 presents a threat to human health and welfare. This statement is strong evidence that at least some members of the committee were working to support a particular policy outcome: revoking the Endangerment Finding. The email also explains how they planned to do it: by attempting to generate “reasonable doubt”. This is going to be hard, Spencer implies. Despite falsely claiming that “2 decades of new science” weakens the case, Spencer explicitly acknowledges that the actual peer-reviewed science of climate change overwhelmingly rejects his position: But if the science argument is decided upon by a vote, or by the number of published citations, we lose the science argument. We can go back even further: This CWG email shares unmistakable DNA with the infamous 1969 tobacco memo that declared: “Doubt is our product, since it is the best means of competing with the ‘body of fact’ that exists in the mind of the general public. It is also the means of establishing a controversy.” The tobacco memo also acknowledges the limit of this strategy: Like the CWG, they knew the science was not on their side. Share The new new Merchants of Doubt The people attacking the IPCC chapter on extreme event attribution are the newest iteration of the Merchants of Doubt. Their goal, like all Merchants before them, is to introduce doubt into the process. Because the report is not even out yet, they cannot attack its conclusions. So they are attacking the authors instead. Here is a press release from the House Science, Space, and Technology Committee: In the letter, the Chairmen express concerns about potential conflicts of interest involving members of the Attribution Committee, stating that “publicly available information suggests a troubling pattern” in which committee members are affiliated with nonprofits that support climate accountability lawsuits, “raising the appearance of impropriety and member bias.” To be clear, this is just innuendo. There is no actual evidence of bias. And given the robust process that these reports go through, including multiple lines of peer review, it seems very unlikely that significant bias can survive into the report. When the report comes out, critics will have the opportunity to make legitimate criticisms of the report — if any exist. If none do, however, they’ll still make criticisms, but they’ll be bogus, simply designed to generate doubt. We’ll see. A note to the press: Fix your frame To any journalists reading this: The public debate over extreme event attribution science is not going away. The science is simply too dangerous to fossil-fuel interests for them to stop fighting it. You very well might be assigned to write an article about this area of research in the future. When you do, do not automatically adopt the framing that climate misinformers want you to use. They want you to frame the story around questions like: Are climate scientists trying to put their thumb on the scale to achieve a predetermined, politically motivated result? Are climate scientists improperly letting their politics invade the science of the IPCC? That frame is a trap. Instead, you need to view this through the historical lens of the Merchants of Doubt. How does the ecosystem of doubt operate? Who funds it? What methods do they use to misrepresent science and slime researchers? What scientific results are they trying to keep people from understanding are legitimate? Ultimately, you instead need to focus your article on the generation of doubt as a way to maintain the fossil fuel industry’s social and legal license to keep burning oil, gas, and coal. If you treat the misinformers’ frame as a legitimate, good-faith scientific critique, you are helping them produce doubt. Don’t do it. Don’t be a Merchant of Doubt. Thanks for reading The Climate Brink! Subscribe for free to receive new posts and support our work. Subscribe other stuff The Staying Curious Substack has an interesting post about the different flavors of climate sensitivity. This is crucial information if you want to understand how scientists think about how much warming the Earth will experience. I’d be grateful if you could hit the like button ❤️ below! It helps more people discover these ideas and lets me know what’s connecting with readers.
World Cup results, schedule, scores, live updates: France vs. Senegal kicks off star-studded day; Norway-Iraq up next
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Live results: Georgia midterm Republican primary runoff
Georgia Republicans will finalize their picks in marquee races for U.S. Senate and governor in a state primary runoff election on Tuesday.
Live results: Alabama midterm primary runoffs
Alabama voters will return to the polls Tuesday to finalize nominees for an open U.S. Senate seat and a handful of other contests in which no candidate received a majority of votes in the May 19 primary.
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Live Results: California special primary election to replace Eric Swalwell
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Georgia Governor Primary Runoff Election 2026 Live Results
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Yankees Rivalry Roundup: Dodgers best Rays on late blast
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‘Marathon’ Season 2 And Free Week Did Not Turn Things Around
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Roundup of third-quarter financial results for Philly-area nonprofit health systems
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SkinVision Pro Launches Globally at HLTH Europe: AI-powered Skin Health Platform Connected To Healthcare Providers
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Iran held by New Zealand in World Cup opener overshadowed by politics
Iran twice came from behind to salvage a 2–2 draw against New Zealand in a World Cup opener overshadowed by geopolitical tensions, protests and months of conflict with the United States. The result leaves…
Dave & Buster's Entertainment Q1 Earnings Call Highlights
Dave & Buster's Entertainment (NASDAQ:PLAY) reported weaker-than-expected first-quarter results for fiscal 2026, with management pointing to macroeconomic pressure in April, a softer consumer backdrop and promotional missteps as contributors to a 5.4% decline in comparable store sales. Chief Ex