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VIDEO: Inside an AI-powered lab trying to replace scientists
The Bulletin goes inside the lab to see how it works and ask whether AI can do science without scientists.
Blizzard video game workers ratify union contract
Nearly 1,900 Blizzard Entertainment video game workers have ratified their first union contract covering wage increases, remote work protections, and AI workplace rules.
Kidpreneurs Fair to give youth business experience, confidence
Business-minded youth can get real-life experience at an upcoming event. The fourth annual Kidpreneurs Fair PA will take place on Sept. 19, offering over 150 young people a chance to set up shop for a day. “I wanted to help kids in the community gain entrepreneurship skills,” said founder Ashruta Shettar. “The earlier kids can […]
Daniel Marshall finds his path in science, one tick at a time
Muscogee citizen Daniel Marshall earned national recognition for his research on Lone Star ticks. Now, he hopes his journey can encourage more Native students to find their place in science.
Blizzard Entertainment Workers Ratify First Contracts
The deals require management to bargain over the use of AI in the workplace and enshrine layoff protections at the Microsoft-owned company.
Are you one of Virginia’s Best Places to Work?
Virginia Business and Best Companies Group invite companies to apply for the 17th annual Best Places to Work in Virginia program to boost culture and retention.
Apple Adds AppleCare One Family Plan for Up to Six People
Apple today announced AppleCare One Family, a new option for U.S. customers that extends AppleCare coverage to every eligible device across an Apple Family Sharing group of up to six people for one fixed monthly price. AppleCare One Family costs $49.99 per month and includes all of the same benefits as AppleCare+, such as coverage for accidental damage like drops and spills, battery replacement service, and priority support from Apple Experts.
ERDC brings science out of the lab with new event
Inaugural Vicksburg Science on Tap will give the public a casual look at research taking place at ERDC.
Science, Technology, Engineering, Math … STEM in action at next Placer County Navy League meeting
The Placer County Council of the Navy League is meeting Monday, Sept. 21.
These small Seattle theater spaces are making big moves
How new energy at Theatre Off Jackson, Annex Theatre and Seattle Open Arts Place is reinvigorating Seattle’s fringe theater scene, and why that matters.
Business owners near the University of Cincinnati push back on street closures meant to curb violence
Business owners in Cincinnati’s CUF neighborhood near the University of Cincinnati say evening street closures put in place following a series of shootings are hurting their bottom lines.
General Duffy's Waterhole goes up for sale in downtown Redmond
Owners of a downtown Redmond community gathering place, taphouse, food truck lot and live music and event space have listed it for sale after eight years in business. General Duffy’s […]
Cabell-Huntington Health Department to Host Drive-Through Flu Vaccine Clinic Friday, October 2 - Cabell-Huntington Health Department
Huntington, WV – The Cabell-Huntington Health Department (CHHD) will host a drive-through flu vaccine clinic on Friday, October 2, from 8:30 AM to 3:00 PM. The clinic will take place […]
Georgia Fans Are Absolutely Furious About This
Georgia football fans will pay for a lot of things. Tickets. Parking. Donations. Merchandise. Streaming subscriptions. Apparently, game highlights are next. Georgia promoted its traditional “Victory Highlights” video following its 63-3 destruction of Tennessee State , except there was one massive catch. The full video was placed behind the Glory Glory subscription service, which starts…
Inside the Buzzy, Controversial Business of Artifact Jewelry
Do ancient artifacts have a place as jewelry, or only in museums? Jewelers and archaeologists weigh in.
NBA’s Dallas Mavericks Seek Zoning for Sports and Entertainment District
The Dallas Mavericks’ chose a likely place to begin the rezoning process for a sports and entertainment district, a onetime thriving mall. The team is looking at 100 acres of land that used to be the Valley View Center. The mall was once home to Bloomingdale’s, Dillard’s and Macy’s in the 1990’s but was shuttered and then ...
Electrical Trade Attracts New Workers; Small Business Optimism Dips in August
WARREN, Ohio – Women are finding a growing place in the electrical trades, with apprenticeship programs in the Mahoning Valley reporting increased interest and enrollment. Young apprentices are gaining experience across residential, commercial and industrial work while preparing for careers in the field.
Swan Town Creative Announces Inaugural Build Business Better Conference for Established Business Owners
A live virtual conference featuring an all-woman lineup of business experts, built to help established business owners explore what's possible and decide what comes next.Marietta, GEORGIA, Sept. 09, 2026 (GLOBE NEWSWIRE) -- Swan Town Creative, a business advisory and consulting firm, announces the inaugural Build Business Better Conference, a two-day live virtual event taking place October 21–22, 2026. Designed primarily for business owners with three or more years of experience who have moved b
Panthers' Bryce Young Placed Toward Bottom of 2026 QB Rankings
Bryce Young has a lot to prove this season with the Carolina Panthers.
Miami Celebrates Breastfeeding with Family Day in Doral - Florida Department of Health in Miami-Dade County
The event took place on August 22 at Doral Legacy Park Community Center.
“Spooky Science Fun Bash” Set for Oct. 9 at Benedictine College
Are your kids looking for a fun way to enter into the Halloween spirit? Look no further than Benedictine College’s Spooky Science Fun Bash! This free, annual event at Benedictine College brings fun, festive science displays to area youth. The event will take place on Friday, Oct. 9, 2026, from
With Sununu vs. Pappas, familiar names will compete in New Hampshire Senate race
Republican John E. Sununu, a former U.S. senator, and Democrat Chris Pappas, a member of the U.S. House, are vying to replace U.S. Sen. Jeanne Shaheen, whose decision not to seek reelection created a cascade of competitive races.
The Dining Table recommends: Taan
If you want crab rangoon, spring rolls and pad thai, this is not the place for you.
Do you think Al could ever become self-aware?
A new study looks at "consciousness steering" in AI, but could this technology actually achieve this level of self-awareness in the first place?
Place-name politics: Why outrage alone won’t erase Trump’s name
Renaming Ottawa’s Trump Avenue is part of a long history of cities engaging in “toponymic diplomacy.”
Science says we're not special. But here's why that could be wrong – and why we should be thankful we've not been swallowed by the Sun | BBC Sky at Night Magazine
Time and place explain the Sun’s odd chemistry. Analysis of 79 ‘solar twins’ suggests we’re different – but not special.
Place-name politics: Why renaming streets named Trump requires more than just outrage
Renaming Ottawa’s Trump Avenue is part of a long history of cities engaging in “toponymic diplomacy.”
Birthright launches Global Business Summit, connecting Diaspora donors, Israeli financial figures
Three-day gathering to take place in November, aimed at showing 'a different face of Israel' to group's funders — and maybe attracting new ones
Where will the Braves finish in team homers?
The last three weeks will be a lot more pleasant the higher you think they’ll place here
Local Business Owners Start New Chapter with Opening of New PostalAnnex Location in Concord, California
Annex Brands, Inc., one of the leading franchisors in the packing, shipping and office services industries, is excited to announce the opening of its newest PostalAnnex location in Concord, CA to new owners, Rebeccah and Konstantin Rybalsky. This new PostalAnnex is set to offer a wide range of essential shipping and office services to the local community, making it easier to provide more service to more people in more places.
‘We’re resilient’: Maine businesses brace for Canadian retaliatory tariffs
Businesses in border states and provinces, including Maine, will feel the squeeze of both sets of tariffs the most. And there likely won’t be a deal in place before the U.S. midterm elections. There have already been some layoffs in…
Dortmund football celebrates a duo that celebrates itself too
After Santiago Mourino’s equalizer for 1-1 (67'), the hoped-for home win against last season’s third-placed team from Spain briefly hung in the balance. Goalkeeper Gregor Kobel even prevented a po...
California voters can fix a flaw in the state's recall system
Proposition 5 on the November ballot would prevent a governor's replacement from taking office by winning just marginal support. It's the first step toward a badly needed overhaul.
Slime mould has no brain, no neurons and no central control, yet when scientists placed food at 36 locations matching cities around Tokyo, it grew a network strikingly similar to the rail system — with comparable efficiency, cost and resilience
A single-celled organism with no brain solved a transportation puzzle that took human engineers decades to perfect.
Nonprofits Are Helping Musicians Pay for Insurance in Austin, Texas, and Beyond
A nonprofit and a local public health agency are subsidizing marketplace health insurance for Austin music artists, even as shifting marketplace conditions make the program a more expensive proposition. It’s becoming a model for other cities and sectors.
Did New Film Unit Just Shift AMC Stock’s Investment Narrative?
AMC Entertainment Holdings recently launched Leawood Films, a film distribution unit based in Los Angeles and Leawood, Kansas, aiming to bring more small and mid-sized movies into theatres worldwide while relying on fully financed projects to limit production risk. The new distributor uses AMC’s excess screen capacity and past concert-film marketing experience to secure theatrical placement for filmmakers who might otherwise struggle to find backing, while leaving most downstream revenue and...
Can Innovative Fabric Science Solve the Workplace Safety Crisis? "All Access hosted by Andy Garcia" Explores Breakthroughs with Portwest
/PRNewswire/ -- Filmed on August 25, 2026, a new segment of "All Access hosted by Andy Garcia" highlights how modern material science is tackling...
Chubb names digital distribution chief for small commercial
Jennifer Burnham will lead Marketplace and API channel expansion for independent agents
John E. Sununu Wins Republican Senate Primary in New Hampshire
The general election race to replace Jeanne Shaheen, a Democrat, could help determine control of the U.S. Senate.
Dodgers replace Shohei Ohtani with Freddie Freeman for Reds game
The Los Angeles Dodgers changed Freddie Freeman's role after an update on Shohei Ohtani.
The 98 Biggest TV Show Flops, Bombs and Misses in the First Half of 2026
(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) In July, I updated my look at how the “streaming bubble” popped since 2023, showing the decline in streaming TV shows over time. But after compiling and analyzing and writing about over one hundred TV show flops in the first half of 2026—I counted 99 “nominees” and there are even more honorable mentions—I couldn’t have told you that the number of shows is going down. When it comes to scripted, English-language TV shows, it feels like we have as many bombs as ever. I don’t keep a specific count, but some streamers probably had as many flops as they’ve ever had.1 That’s right, it’s time for part two of my analysis of the biggest flops, bombs and misses on streaming in the first half of 2026. Two weeks ago, I took a look at films. Today, TV shows. If you want to read the full methodology for how I assemble this list, you can find it at the bottom of this article. In short, this list is… ...scripted and unscripted TV shows,...from the nine major streamers,...in the US (using US-only ratings),...excluding true crime, kids and foreign-language shows,...that got no/poor ratings,...from Jan-2026 to the end of June-2026. Reminder: this article does not represent my personal opinion—many of these shows are great!—but I follow the data, and a miss is a miss and a bomb is a bomb. Also, price matters. If a TV show costs north of $100 million, it needs to get lots and lots of streaming viewership to justify that budget. As with past editions, I ordered this list by streamer, going from best (fewest flops) to worst (the most misses)—taking the size of the flops into consideration—and like the last edition, three or four streamers vied to take the win/loss of having the most flops. (But the actual winner is no surprise.) I try to avoid tooting my own horn too much, but seriously, in just under 5,000 words (including the methodology section) I provide a mostly comprehensive overview of the eight major streamers (Netflix, Disney+, Prime Video, Hulu, HBO Max, Peacock, Paramount+, and Apple TV) for the first half of the year, mentioning most of their hits and all their misses. It summarizes the entire first half of 2026! If you want to support this work, please subscribe. Subscribe Tubi Big Mood Boarders The Freak Brothers Twenty Twenty Six Honorable Mentions: Busted on Bodycam, Deestroying the Pitch, Destination World Cup 2026 I don’t think that Tubi spends all that much making or (mostly) licensing these original TV shows—Big Mood, Boarders and Twenty Twenty Six all come from the UK—but they’re not free and they didn’t chart anywhere. Winner: The Freak Brothers Have you even heard of this show? It’s an animated comedy...that’s on its third season! And Pete Davidson, Woody Harrelson, John Goodman and Tiffany Haddish all provide voice talent for it. Yes, animated shows don’t cost as much as live action shows, but cheap isn’t free! So a show with this level of talent needs to perform better. Disney+ Daredevil: Born Again Star Wars: Maul – Shadow Lord Honorable Mentions: Behind the Attraction, Donna Hay Coastal Celebrations, We Call It Imagineering Disney+ doesn’t make all that many original shows anymore. They had two flops, and one was animated. Their one not-a-miss show, Wonder Man, got just good enough viewership to not be considered a “miss”...but it’s since been cancelled. At this point, Disney has pivoted entirely away from making big budget TV shows for Disney+ to making...almost nothing for Disney+? Sure, Disney’s spending circa 2019-2022 was unsustainable, but now they’re pivoting too far in the other direction. At some point, Disney needs to stop shifting strategies so wildly. Really, Disney should have made fewer shows for Disney+ at launch and the shows they did make at that time needed to be made at more reasonable budgets. And they should adopt that strategy now. Winner: Daredevil: Born Again Daredevil, the Marvel Comics character, is on my personal Mount Rushmore of favorite superheroes, so it pains me to give him the win/loss today, but this show deserves it. I’ll repeat my hot take from last spring: “Based on his popularity, Daredevil should be in movies, and probably ones that cost a lot less than the MCU’s usual price tag. Disney/Bob Iger/Ike Perlmutter (who, based on reporting, made the decision) made a huge mistake selling TV shows to Netflix in the 2010s, thus limiting this character to the small screen. Daredevil could have anchored Marvel’s post-Infinity War plans, and if he did, the MCU would probably be in a better place than it is now.” HBO Max We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… What four streamers had the most misses... HBO’s strong start to 2026… The caveat to Peacock’s turnaround this year... Paramount+’s key man problem… What country isn’t delivering hits for Netflix or Hulu... The cavalcade of stars on a streamer where no one is watching their shows... Across nearly 5,000 words of analysis… And a lot more... ...please subscribe! We can only keep doing this great work with your support. If you’d like to read more about why you should subscribe, please read this article about the Streaming Ratings Report, why it matters, why you need it, and why we cover streaming ratings best.
Lancaster County judge dismisses challenge to Nebraska K-12, collegiate sports ballot measure
A judge dismissed all objections to a ballot measure seeking to place sex-separate school sports requirements in the Nebraska Constitution.
Orchard Place names Haselhuhn vice president of advancement
Orchard Place has named Adam Haselhuhn its new vice president of advancement, effective Sept. 14. Haselhuhn has more than 14 years of experience in higher education and healthcare philanthropy, most recently serving in senior development leadership roles at the John Stoddard Cancer Center and UnityPoint Health – Des Moines Foundation. He previously served as director…
Senate Set to Vote to Begin Debate on Protect College Sports Act
Background The Protect College Sports Act of 2026 (PCSA), introduced in the Senate on June 2, 2026, by Senators Ted Cruz (R-TX) and Maria Cantwell (D-WA) and joined by Senators Eric Schmitt (R-MO) and Chris Coons (D-DE), represents a comprehensive federal legislative effort to reshape the governance and economics of intercollegiate athletics, including redistributing the significant media revenues generated by college sports. Reported favorably 19-9 from the Senate Commerce Committee and placed on Senate Calendar No. 449 on June 24, 2026, the PCSA was substantially revised on August 7, 2026 (Senate Amendment 6768). The PCSA arrives against a backdrop of cascading judicial decisions that have systematically dismantled the National Collegiate Athletic Association’s (NCAA) authority to regulate the economics of college sports.
Ticket package secures your place for the match against Santos
Galo will face three major home challenges in September, including the decisive Copa Sudamericana quarterfinal match against Santos, and the Massa can now secure their place at Arena MRV with a specia...
DMTC gets mysterious and spooky
Whether it’s new love, enduring love, misunderstood love, or even love for the moon, it seems that every kind of love has a place in “The Addams Family.”
UND again named among region’s best places to work
Prairie Business recognition reflects workplace culture created by UND faculty and staff.
Third kit to debut against Fluminense
The debut of Galo’s third kit, in orange, will take place in next Saturday’s match (12/9), at 4:00 p.m., against Fluminense, at Arena MRV. The match will be valid for the 27th round of the Brazili...
OECD: Heavy AI Use Linked to Lower Science Scores
New PISA data shows students who use AI daily score 28 points lower in science; OECD urges using AI to support, not replace, learning.
More evidence that mass shootings are suicidal acts
New research finds national peaks for suicides, gun rampages take place within days of each other in summer.
Strengthening Global Health Systems: Jeanna Holtz (’79), Nutrition & Exercise Physiology
When Jeanna Holtz, Nutrition and Exercise Physiology alum, updated her estate plans, she found herself returning to the place where her journey began: Washington State University.
Cowboys Predicted to Add Champion George Pickens Replacement
The Dallas Cowboys could have a high-scoring offense with George Pickens back. But assuming he leaves after this year, could a college star replace him? The post Cowboys Predicted to Add Champion George Pickens Replacement appeared first on HEAVY.
Gone but not forgotten – Indigent Remains Ceremony 2026
The King County Medical Examiner's Office Indigent Remains Program provides burial for King County residents who have died without resources or family to claim their remains for a proper burial. The next ceremony to remember these individuals will take place on Wednesday, October 7, 2026, at 1 p.m. at Mt. Olivet Cemetery in Renton (100 Blaine Ave NE). It’s open to any member of the public who wishes to pay their respects.
Smithsonian head Lonnie Bunch to retire amid Trump administration effort to reshape institution
Lonnie Bunch III said Tuesday that he will retire as the head of the Smithsonian Institution, a role that placed him at the center of President Donald Trump’s efforts to reshape the world’s largest museum organization.
Business internship presentations connect classroom learning to career readiness
Nineteen Penn State Lehigh Valley business students concluded their required summer internships by presenting what they learned to faculty and staff evaluators. The presentations culminated a semester-long process designed to help students connect their academic preparation, workplace experiences and career-readiness skills.
Liverpool’s hunt for a new sporting director: Julian Ward and the standout internal options
FSG president Mike Gordon is leading the search for Richard Hughes' replacement, with both internal and external candidates being considered
Live Results: New Hampshire midterm primaries
The race to replace retiring three-term Democratic Sen. Jeanne Shaheen is one of a handful across the country that could determine control of the U.S. Senate for the second half of President Donald Trump’s final term.
Behind the scenes of Hard Rock Casino Tejon’s Third Eye Blind private concert
METTLER, Calif. (KGET) — An extra special concert took place Monday night at Hard Rock Casino Tejon. 17 News got an exclusive behind-the-scenes look at what it takes to prepare for the Third …
The Row brings new retail, dining and entertainment to Heartwood
The Row, a new in-line retail center located in Poplar Place within Heartwood’s Town District, will bring a growing mix of dining, entertainment, services and specialty retail to one of the community’s most visible commercial areas at Exit 82.
Rogers and OEG Sports & Entertainment Extend Strategic Partnership for 10 More Years
Rogers is giving away more than 1,500 tickets to customers throughout season, including 300 for Home OpenerEDMONTON, Alberta, Sept. 08, 2026 (GLOBE NEWSWIRE) -- Rogers and OEG Sports & Entertainment (OEGSE), today announced a 10-year extension of their strategic partnership, keeping Rogers Place as the home of the Edmonton Oilers through 2036. This extension comes as the iconic Rogers Place is celebrating its 10-year anniversary. To mark the occasion, Rogers is awarding more than 1,500 Oilers ti
Pete Davidson reveals emotional 9/11 connection to Michael Strahan: ‘You put me on your shoulders’
In a new documentary, Davidson and Strahan recall and relive the happy meeting that took place amid tragedy and pain.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Sunderland 'deserved more' at Brentford
Marco Gabbiadini says Sunderland deserved to win at Brentford after taking the game to their opponents on Saturday. The former Sunderland striker, speaking to Radio Newcastle, believes the Black Cats' attacking approach could have earned them all three points and suggested the result could prove significant when looking back at the end of the season. "If you finish the season in a similar position to what we finished last season and you look back over it, you might look back and think this is one that could have taken us another place up the table," said Gabbiadini.
This Lafayette artist turns mud into the places people never want to forget
Over the years, Kai Drobish has has created items representing a lighthouse in Australia, a castle in Cuba, churches in Spain and Italy, hospitals in the United Kingdom, country houses in England and Scotland and a château in France.
'T Nation': More men turning to testosterone replacement therapy. What it means for health
In collaboration with the Hearst magazine, "Men's Health," WBAL-TV 11 News examines the increase in testosterone replacement therapy, and what it means for men.
Trust in Jackson crucial for Emery
Ollie Watkins' departure to Al-Hilal - which lurched between acrimonious and emotional - has left Aston Villa without their best attacking outlet. Despite just one goal in his first 13 top-flight games last season, he ended up netting 16, leaving him on 91 Premier League goals - a club record. Nicolas Jackson was brought in as Watkins' direct replacement and was a priority signing for Unai Emery, having worked together at Villarreal.
Assessing Kelp Bed Expansion Around Kodiak Island in Alaska - NCCOS - National Centers for Coastal Ocean Science
Scientists from NOAA’s National Centers for Coastal Ocean Science Kasitsna Bay Laboratory joined a week-long mission to investigate the recent expansion of giant kelp forests in waters surrounding Kodiak Island, Alaska. Bull kelp, the predominant canopy kelp in the region, has been largely replaced by giant kelp in the last couple of decades. While both ... Read more
Steve Flowers: Political reassurances and revelations in 2026
Faces and places and races change in politics, but one thing that stays the same is the candidate who has the most money for campaign advertising and vote gathering, nine times out of ten wins.
MDI Health to Honor Mount Desert Nursing Association with 2026 Impact Award
BAR HARBOR—MDI Health will honor Mount Desert Nursing Association (MDNA) as its 2026 Community Partner of the Year during the organization’s Annual Meeting and Community Celebration on Tuesday, September 15. MDNA will receive the 2026 Impact Award in recognition of its longstanding commitment to providing in-home nursing, physical and occupational therapy, and medical equipment to the Island region. By caring for people where they live, MDNA helps patients remain safely and independently at home, providing reassurance and support to their families. “Mount Desert Nursing Association exemplifies the power of community partnership,” said Chrissi Maguire, President and CEO of MDI Health. “Its nurses bring skilled, compassionate care directly into people’s homes, helping patients navigate illness, recovery, and some of life’s most difficult moments. We are deeply grateful for MDNA’s service and the important role it plays in the health of our community.” MDNA works closely with MDI Health providers and care teams to support continuity of care following hospitalization, surgery, illness, or changes in health. Its personalized services extend care beyond the hospital and help ensure patients receive the support they need close to home. “For 77 years, MDNA has been here for our community, helping our neighbors recover and remain safely at home. Our long-standing partnership with MDI Health is an important part of making that possible. Together, we help ensure a seamless transition from hospital to home and provide patients with the continued care they need. We are incredibly grateful for this recognition and especially proud of our talented and hardworking team,” said Amy McVety, Executive Director of Mount Desert Nursing Association. The Impact Award will be presented during MDI Health’s Community Celebration from 5 to 7 p.m. at the Bar Harbor Club. The event will also recognize outstanding employees, volunteers, and trustees; celebrate MDI Health’s achievements over the past year; and mark a transition in Board leadership as Madeleine Braun, PhD, MBA, prepares to succeed Martha Wagner, PhD, as chair. The celebration will feature music, refreshments, the MDI Health Auxiliary Raffle, and a cash bar. MDI Health’s Annual Business Meeting will take place from 3:30 to 4 p.m. via Zoom. These events are free and open to the public, but space is limited. To reserve your spot, contact Patrianna Anderson at 207-288-5082, ext. 1432, or visit mdihospital.org/communitycelebration. Subscribe Share Leave a comment
Taiwan students rank 4th globally in science, 3rd in reading: PISA 2025
Taiwan's 15-year-old students ranked fourth in the world in science and mathematics and achieved a record-high third place in reading literacy in the 2025 Programme for International Student Assessment (PISA), the Ministry of Education and National Taiwan Normal University (NTNU) announced Tuesday.
I'm an airline employee who flies for free, but there's a big catch
I've flown to places like Machu Picchu and the Great Wall of China on a whim, but I sometimes get stuck overseas or have to buy a costly ticket home.
Scientists observe Einstein’s gravity in the quantum world for the first time
Physicists have directly observed a long-predicted quantum effect of gravity, putting one of Einstein’s foundational ideas to a striking new test. Using ultracold atoms, researchers split an atom’s quantum wave so that one part was held in place while the other fell freely under gravity, then reunited the two to measure the tiny difference that emerged.
Who watched B1G football in week 1….and week zero?
B1G stadiums are big….were they full? Fans can be a fickle lot. And they are different, depending on where you are. Can you imagine Nebraska not selling out? Can you imagine Rutgers always selling out? There are always reasons for people to not attend a game.. it’s just that in some places you’re ostracized if […]
We Might All Pay For Corpus Christi’s Water Crisis
The Sparkling City by the Sea is the nation’s largest energy exporter. Costs could rise for all of us as it confronts an existential threat of its own making. Decades of overconfidence and complacence got it here.
Man Utd fans group call for derby-day ticket protest
The 1958 Manchester United fans' group is organising a protest ahead of Sunday's derby clash with Manchester City in protest at the club's handing of its ticket touting crackdown. United identified numerous instances of what they felt was ticket touting and in July placed restrictions on a large number of accounts and demanded details for why single devices were being used for multiple accounts, amid a threat of them being withdrawn. The message also warned the fan their season ticket could be deactivated for a Premier League game if they didn't buy a ticket.
2027 rates established for Del. Health Insurance Marketplace Coverage
What will be the cost of 2027 coverage under the Affordable Care Act?
Reds want long-term Hughes replacement
With Richard Hughes' move to Al-Hilal now confirmed, Liverpool are seeking a new sporting director for the fifth time since 2022. Hughes joined Liverpool in the summer of 2024 and oversaw the appointments of Arne Slot then Andoni Iraola. Mike Gordon, the president of Fenway Sports Group (FSG), is overseeing the process of finding Hughes' replacement, with Liverpool keen to make a swift appointment.
How Energy Justice Is Changing Women’s Lives in Blantyre
By Temwanani Banda, Blantyre, Malawi Every day, before I think about my business, my family or even myself, there is one question that has always come first: How will we cook today? For many women in Blantyre District, Malawi, cooking begins long before a pot is placed on the fire. It begins with finding fuel. […]
Anthony Edwards Says Atlanta Is Among Favorite Places To Play
Minnesota Timberwolves star Anthony Edwards included his hometown of Atlanta after being asked to name his favorite place to play.
When Scientists Become Commercial Influencers
Peer review in reputable journals gives scientific claims an authority that commercial speech rarely enjoys. But what happens when scientists carry that halo of authority out of the laboratory and into the marketplace, publicly attacking products while enjoying protections their manufacturers do not?
Tampa Bay Buccaneers RB: ‘Game Time Decision’ Against Bengals
After Monday’s practice for the Tampa Bay Buccaneers, Sean Tucker’s status for the season opener against the Cincinnati Bengals seems in question. Tucker was not a participant in Monday’s drills, and the team could look to promote Josh Williams from the practice squad to take his place on the roster. The nature of the injury […] The post Tampa Bay Buccaneers RB: ‘Game Time Decision’ Against Bengals appeared first on HEAVY.
Tom Brady refuses to apologize for conflict of interest
Ever since seven-time Super Bowl champion Tom Brady stepped into a role as a broadcaster with Fox while also becoming a part owner of the Las Vegas Raiders franchise, he has faced criticism over potential conflicts of interest and how the limitations placed on him might impact his career as a broadcaster. Brady, however, doesn’t…
Detroit Lions Name 7 Captains for 2026 Season
The Detroit Lions have selected seven captains for the 2026 season, with Jack Campbell, Alim McNeill and Jack Fox earning the honor for the first time. The selections reveal a leadership transition taking place around Detroit's established core.
Can what we feed farm animals directly benefit our own health? Our research suggests it can
Chronic lifestyle diseases place growing pressure on healthcare. Prevention strategies should go beyond consumer behaviour and address how food is produced.
Two years after Helene, Labor Day brings reopened parks and businesses
This month marks two years since Hurricane Helene. Business owners and residents say this Labor Day feels different, as more places and recreation areas reopen.
Lions Reveal Captains For 2026 Season With One Surprise Addition
With the preseason wrapped up, the Detroit Lions can now turn their full attention toward the upcoming 2026 campaign and their quest to return not only to the NFL Playoffs, but to what they feel is their rightful position in first place of the NFC North Division.The Lions have also named their team captains for […] The post Lions Reveal Captains For 2026 Season With One Surprise Addition appeared first on HEAVY.
Chivas, growing ever stronger in the Apertura 2026
The Apertura 2026 has represented a growth process for Chivas under Gabriel Milito. After 7 Matchdays, Guadalajara currently sits in second place in Liga MX with 14 points, thanks to a haul of 4 wins,...
Bumbershoot 2026 proves Seattle’s signature festival is in a really good place
With an intentional, finely tuned lineup, organizers offered the clearest vision of what Bumbershoot can — and should — be.
Protesters push to stop Academy of Natural Sciences from closing museum
A protest is set to take place outside the Academy of Natural Sciences of Drexel University on Tuesday, Sept. 8, to stop the closure of the museum.
Tyler Smith out at least four weeks
Cowboys OG Tyler Smith will be placed on Injured Reserve because of thumb injury
Antonelli's feat at Monza shows how he's shifting the F1 spotlight from Ferrari in Italy
For so long, Formula 1 in Italy has meant Ferrari. The 20-year-old Mercedes driver’s charge from the back to win his home grand prix sealed Antonelli’s place in the pantheon of Italian sports performances. Having started 19th, it was the furthest back any driver came from to win in more than four decades.
Drew Brees replaces Maxx Crosby on SiriusXM’s ‘Let’s Go!’
The media renaissance of Drew Brees continues unabated. Not only will the former New Orleans Saints quarterback embark on his first full season in the booth alongside Adam Amin for the NFL on Fox, but the 47-year-old will also co-host SiriusXM’s Let’s Go! alongside Matthew Stafford, Jim Gray and Peter King, effectively replacing Las Vegas…
Chelsea Turn Down Signing Of Free Agent Despite Midfield Concerns
With Chelsea hunting for an Enzo Fernandez replacement, the Blues have been alerted to the free agent market in search of solutions.
Puka Nacua suspension could be avoided, per NFL insider
Puka Nacua was not placed on the Commissioner’s Exempt List.
Stillwater middle schooler places in national Top 300 for young scientists
A middle schooler from Stillwater beat out nearly 2,000 middle school students across the country to win a national STEM award.
Scientists covered 200 square metres of a Swiss glacier with sheep’s wool; early tests found it protected the ice about as well as plastic sheets, but only 0.02% of Swiss glacier ice is covered
A natural wool covering placed over 200 square metres of high-altitude Alpine ice has proved as effective at slowing summer melting as conventional synthetic tarpaulins, offering a possible biodegradable alternative to plastic sheets. Initial results from the "Keep It Wool" trial on the Tsanfleuron Glacier in western Switzerland show that prototype wool blankets protected snow and ice from heat about as well as plastic geotextiles.
Chaney: Mississippians deserve more affordable health insurance options
Over the past year, more than 200,000 Mississippians have left the Affordable Care Act marketplace as the cost of coverage has increased due to the expiration
Readers respond: Portland, the capital of identity politics
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