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Parham Doctors' Hospital's new intensive outpatient program expands behavioral health continuum of care
Parham Doctors’ Hospital recently launched a new adult intensive outpatient program, expanding access to behavioral health services for people who need more support than traditional outpatient care but do not require an inpatient hospital stay. The new program is designed to serve adults experiencing mental health challenges such as depression,
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Mikel Dashtipour has joined Renal Specialists of Northwest Arkansas, where he provides care for patients with kidney disease, including those with chronic and end-stage kidney disease, electrolyte imbalances, fluid overload and other related conditions, and those receiving dialysis.
Business People
Mikel Dashtipour has joined Renal Specialists of Northwest Arkansas, where he provides care for patients with kidney disease, including those with chronic and end-stage kidney disease, electrolyte imbalances, fluid overload and other related conditions, and those receiving dialysis.
NHS app to use AI to determine which service best for patients
The update will be available to all users in England by April 2028, the health service says.
France’s First Ebola Patient Has Recovered, Health Minister Says
A doctor who was diagnosed with Ebola in France last month after doing humanitarian work in the Democratic Republic of Congo has recovered and left the hospital.
Harsh Medicine: Fixing Science’s Gender Gap
Women now enter medicine in numbers equal to men, yet they remain largely underrepresented. That’s harmful to science and patient care.
Two stricken with Legionnaires Disease on Upper East Side, cluster investigated: NYC health officials
The patients were found in the Yorkville and Carnegie Hill neighborhoods of the Upper East Side, in zip codes 10028 and 10128, city officials said.
Anthropic wants to develop its own drugs
The AI drug boom has a long way to go before reaching patients.
Digital diabetes tool shown to improve patient care and cut health care costs
A new study by University of Manchester researchers has linked a digital platform helping people manage type 2 diabetes to better blood sugar control, improved health and potential long-term NHS cost ...
Atrium Health settles online portal lawsuit for $1.8 million; patients eligible for payouts
It involves patients who had a MyAtriumHealth or MyCarolinas account at any time between Jan. 1, 2015, and April 10, 2024.
Atrium Health settles online portal lawsuit for $1.8 million; patients eligible for payouts
It involves patients who had a MyAtriumHealth or MyCarolinas account at any time between Jan. 1, 2015, and April 10, 2024.
2 dead after shooting at Springfield Mercy Hospital parking garage; mental health experts urge grace for grieving staff
Two people are dead after a shooting at a Mercy Hospital parking garage early Thursday morning, and mental health professionals are urging those affected — including hospital staff — to be patient with themselves as they grieve.
Legacy Business Spotlight: Baton Rouge Clinic
— ESTABLISHED 1946— The Baton Rouge Clinic, AMC has been delivering patient-centered care to the Capital Region for 80 years. Founded by four local physicians, the clinic has grown from a single practice into a network of 18 locations serving nearly 400,000 patients across Louisiana, while remaining true to the physician-led model thathas defined it […]
Could your gut bacteria really slow Alzheimer’s? Scientists reveal a surprising link - Futura-Sciences
European researchers previously demonstrated that transferring stool samples from human Alzheimer’s patients into healthy rats triggered symptoms like spatial memory issues. Other models show that altering gut microbes changes the buildup of amyloid plaques and tau proteins, the two main hallmarks of the disease. Scientists have even found that certain...
Mystery parasite leaves Americans battling ‘explosive diarrhea’ as CDC investigates
The CDC reports 145 confirmed cyclosporiasis cases across 17 states as the parasitic outbreak season climbs, with 20 patients hospitalized so far.
Patient Care Center structure changing for physical medicine and rehabilitation
The changes align with Vanderbilt Health’s strategic vision for growth, including regional expansion and the development of innovative rehabilitation and pain medicine services.
Trump admin proposes rule it says could save Medicare patients $1.1B on drugs
The change would apply to hospitals that serve low-income patients
Trial for Bundibugyo Ebola treatment starts in DRC, WHO says
A treatment trial for the Bundibugyo Ebola outbreak in the Democratic Republic of Congo enrolled its first patient on Thursday, marking a milestone in efforts to combat the epidemic, WHO chief Dr. Tedros Adhanom Ghebreyesus told reporters.
Once a source of national pride, Cuba’s healthcare system declines as energy shortages deepen crisis
Irisleydis Tristá, a cancer patient in Cuba, has been unable to get a crucial CT scan for seven months because the machine at Havana’s leading hospital is broken.
Marshall Health Network first in West Virginia to offer histotripsy treatment for liver tumors
HUNTINGTON, W.Va. – Marshall Health Network–Cabell Huntington Hospital (CHH) is the first hospital in West Virginia to treat liver tumors using the Edison® Histotripsy System, giving patients access to an advanced treatment that targets tumors with focused sound waves instead of surgery, chemotherapy or radiation. The Edison Histotripsy System uses image-guided sonic beam therapy to precisely target […]
U.S. Healthcare Spending’s Meager Return On Investment
The U.S. spends a lot on healthcare — in terms of total and per capita expenditures and patient out-of-pocket costs — but gets a relatively poor return on its investment.
How remote patient monitoring advances affordable healthcare
As global medical costs face double-digit spikes, remote care is a clinical tool and an economic necessity.
Patient enrolment begins in a scientific trial to identify the first effective treatments for Bundibugyo virus disease
In a major international effort to evaluate potential treatments for Ebola disease due to Bundibugyo virus (BVD), the PARTNERS clinical trial has opened enrolment today for patients in the Democratic Republic of the Congo.
Elevance pays CMS $342M to assuage concerns of noncompliance and overbilling
The Medicare Advantage insurer said the payout is equal to what a CMS audit stated was the total amount the company was overpaid for patient care services. Despite receiving the cash, the agency has yet to officially withdraw its enforcement action, as the two parties are still negotiating.
UToledo Health Pharmacy Residency Program Awarded Competitive National Grant
A $25,000 ASHP Foundation grant will grow UToledo's PGY1 Pharmacy Residency Program to seven residents, helping meet growing demand for pharmacist-led patient care.
Statins and blood pressure drugs changing health risks of obesity, study suggests
New research shows obesity patients over 40 are managing blood pressure and cholesterol as well as healthy-weight peers, but younger adults remain at risk.
Trinity Health Grand Rapids works to offer more free medication
Trinity Health Grand Rapids is rolling out a new program that aims to get prescription medicine to some of the lowest-income patients in West Michigan.
Marion County leaders blast 'unnecessary' OHA rules, demand rescission
Marion County leaders are asking the Oregon Health Authority to rescind recent rule changes they say endanger patients, staff and the community.
AG Sunday Ensures Protections for Patients via Settlement after Review of Allegheny Health Network’s Acquisition of Heritage Valley Health - PA Office of Attorney General
HARRISBURG – Attorney General Dave Sunday and the Office of Attorney General’s Antitrust Section announced a court-approved settlement that will protect patients, physicians, and health plans potentially impacted by Allegheny Health Network’s (AHN) recent acquisition of Heritage Valley Health Systems (HVHS). The Office of Attorney General thoroughly reviewed the transaction and outlined a number of […]
Healthy Returns: Walmart, CVS step in to help seniors navigate Medicare coverage of obesity drugs
Medicare has started covering obesity drugs for the first time – and companies like Walmart and CVS Health are playing an important role for patients.
CMS proposes updates to home health payments for CY 2027, updates to provider enrollment and quality and value-based purchasing programs
The Centers for Medicare & Medicaid Services July 1 issued its calendar year 2027 proposed rule for the home health prospective payment system. The rule proposes a 2.4% update, which includes a 3.1% market basket update, reduced by a 1.0 percentage point cut for productivity, as well as an 0.3 percentage point increase related to outlier payments. In addition, the agency proposes a temporary cut of 3.0% that it states is necessary to achieve budget-neutral implementation of the Patient-driven Groupings Model.
IU Health's 3D printing studio helps surgeons prepare and educate patients
The health system received approval from the U.S. Food and Drug Administration in January for the IU Health 3D Print Studio.
NHS to take over troubled Northampton mental health hospital
The removal of almost 300 patients from the Northampton site was ordered by NHS England in March.
Register to attend Rural Health Initiative series on substance use
Experts from the Johns Hopkins Bloomberg School of Public Health and WVU School of Public Health will discuss their experiences working with patients who use substances in rural areas and potential areas for future research projects from noon to 1 p.m. July 16 on Zoom.
Simpler lung cancer screening criteria could capture more patients likely to benefit
New research published in JAMA Internal Medicine compared current USPSTF criteria to a potential shift toward total years smoked, rather than pack years.
Nearly 100% of patients surveyed say they’d want to know when AI is used in imaging
Researchers recently sought to better understand how patients perceive rapidly evolving advancements in AI, sharing their findings in RSNA’s Radiology.
85% of hospitals experienced ‘vendor disruption’ in last year, as most brace for cyberattack inevitability, report shows
An analysis from cybersecurity consultancy group Omega Systems reveals that most healthcare practices place too much trust in their third-party vendors to secure patient data, neglecting their own IT systems in the process.
Hospital sued after drug addict nurse allegedly causes death of two patients
An emergency department nurse at Heritage Valley Sewickley Hospital is accused of stealing drugs and neglecting patients, causing at least two fatalities. A lawsuit filed by two whistleblowers further alleges that hospital leadership covered for the drug-dependent nurse.
Servers recalled after glitch results in radiologists reading images for wrong patients
The issue could cause a reader to unintentionally report on the wrong patient when using interactive applications, according to a notice from the FDA.
Bethesda Health Clinic reaches $25M fundraising goal for new Tyler facility
Clinic says new 61,000-square-foot building will serve 50% more uninsured patients starting spring 2027
Multnomah County Just Fired a Key Health Leader. He Says He’s a Scapegoat in a Power Struggle.
Anirudh Padmala’s departure marks worsening tumult in the top leadership overseeing the network of 19 federally-funded Portland area clinics, which collectively serve tens of thousands patients annually.
Western Pa. nurse accused in lawsuit of causing 2 patient deaths, stealing drugs
A federal lawsuit accuses Heritage Valley Health System and staff members of enabling alleged crimes by emergency department nurse Nolan Chismire, including drug theft, false insurance claims, and failures in patient care allegedly linked to two deaths.
ARDS patients improve with experimental treatment
JUPITER, Fla. — Doctors have few options for patients who develop a life-threatening lung condition called acute respiratory distress syndrome, or ARDS. A…
SGMC Health Names Chad Nelms Associate Vice President of Nursing
SGMC Health announces the promotion of Chad Nelms, RN, to Associate Vice President of Nursing. In this role, Nelms will provide strategic and operational leadership for nursing services across the organization, supporting a cohesive and patient-centered approach to care.
All of Us tests a new approach to collect real-world data for research
The NIH All of Us Research Program has secured thousands of electronic medical records through an innovative use of patient data-sharing networks
Think Insurance Denials Only Hurt Patients? Why Business Owners Are Paying the Ultimate Price
A simple 9-week delay for a critical medication resulted in a $50,000 surgical nightmare. Here is how healthcare bureaucratic delays quietly destroy your company's bottom line.
Scientists cured sickle cell. Then their next challenge began.
Gene editing has delivered remarkable results against sickle cell disease. Now researchers are working to make these personalized treatments faster, cheaper, and available to far more patients.
Holyoke Medical Center earns national award for improving patient experience
Holyoke Medical Center has received national recognition for its efforts to improve the patient experience through technology.
Cost and utilization of inpatient mental health and substance use treatment - Peterson-KFF Health System Tracker
Approximately 1 in 5 people with private health insurance have any mental illness, and 1 in 20 have a serious mental illness. This brief examines inpatient mental health and substance use treatment admissions in 2023 among adults aged 18-64 with large employer-sponsored health insurance plans. Private insurance enrollees constitute roughly a quarter (26%) of mental […]
To reduce wait times, UVM Health is demanding its docs see more patients
A recent report commissioned by a state-appointed overseer largely blames long wait times on low productivity among the network’s doctors, and argues wait times also contribute to unnecessarily high prices.
DMC Sinai-Grace holds 2nd annual health fair with free screenings, food, entertainment
DMC Sinai-Grace Hospital is taking patient care beyond the hospital walls and into the heart of the Detroit community.
DMC Sinai-Grace holds 2nd annual health fair with free screenings, food, entertainment
DMC Sinai-Grace Hospital is taking patient care beyond the hospital walls and into the heart of the Detroit community.
IU Health opens one of nation's first FDA-cleared 3D-printing studios
It's changing how doctors work and talk to their patients.
The ERs that can turn patients away
The hospital operator Nutex enriched itself by exploiting loopholes in laws meant to protect patients, STAT found.
VSP Vision Announces Winner of Propel Student Business Challenge Scholarship
RANCHO CORDOVA, Calif.—VSP Vision, in collaboration with the Student Optometric Leadership Network (SOLN), today announced that Mason Martin, a student at the University of Alabama at Birmingham School of Optometry, is the winner of the 2026 Propel Student Business Challenge Scholarship, powered by PECAA. Martin, who was awarded the $10,000 scholarship and a travel grant to attend the SOLN conference in Denver, is the first first-year student at the school to receive this honor, the announcement said. VSP said his standout submission featured a thoughtful, patient-centered private practice business plan.
Aligning patient and planetary health: planetary health diet adherence and inflammatory bowel disease prognosis across Western and Eastern cohorts
npj Science of Food - Aligning patient and planetary health: planetary health diet adherence and inflammatory bowel disease prognosis across Western and Eastern cohorts
These fat-filled brain cells may be making multiple sclerosis worse
Scientists have uncovered a surprising clue that may help explain why multiple sclerosis (MS) progresses rapidly in some people but not others. In brain tissue from patients with severe MS, researchers found large numbers of “foamy” immune cells packed with fat droplets after absorbing damaged myelin. These overloaded cells appear to switch from helping repair the brain to fueling ongoing damage and inflammation.
Meaningful Outcomes Determine the Winners of the Health AI Race
Global investment in healthcare AI exceeded $18 billion in 2025, yet health systems still lack a shared understanding of the outcomes that investment should deliver. This paper argues that success in the health AI race will be determined not by technological sophistication but by which systems first identify and pursue the outcomes that matter most to patients, professionals and health systems. Without a shared language for defining and measuring what healthcare AI should deliver, systems risk optimizing for what is easiest to count rather than what matters most. This paper provides a framework for ensuring AI investment translates into real value for healthcare systems and the populations they serve.
NI health: Resident doctors begin strike action over pay
The BMA said there will "undoubtedly be cancellation of operations, outpatient appointments and elective care" but "patient safety will still be prioritised".
England facing children’s mental health ‘crisis’ as referrals hit 1m
Commissioner calls for overhaul of state support after reporting 10% rise in young patient referrals last year
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial
Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to
Catherine completes Three Peaks Challenge to 'explore life beyond' cancer diagnosis
The Princess of Wales did the endurance event to raise awareness about "holistic healthcare" for cancer patients.
Lille reveal Ayyoub Bouaddi stance amid Liverpool interest
Liverpool Face Patient Lille Stance Over Ayyoub Bouaddi TransferLiverpool’s interest in Ayyoub Bouaddi has moved into sharper focus, with AS reporting that Lille are prepared to take a patient appro...
Brain activity under anesthesia challenges what we know about consciousness
The unconscious brain appears to be far more capable than scientists once believed. Researchers found that patients under general anesthesia could still process language at a sophisticated level, distinguishing nouns, verbs, and adjectives while listening to stories. Even more remarkably, neural activity showed signs of predicting upcoming words before they were heard. The results challenge traditional ideas about consciousness and hint at new possibilities for brain-computer interfaces.
Patients can save thousands with drug coupons, but only if insurers honor them
Patients who rely on co-pay assistance from drugmakers are typically heavy users of health care for whom delays in treatment or worsening conditions can lead to higher costs, according to patient advocates.
Trump admin rule puts reproductive health care for 160K Pa. patients at risk, lawsuit says
A lawsuit says family planning and health organizations in Pennsylvania could face federal funding delays or denials due to a new Trump administration policy.
Trump admin rule puts reproductive health care for 160K Pa. patients at risk, lawsuit says
Spotlight PA is an independent, nonpartisan, and nonprofit newsroom producing investigative and public-service journalism that holds power to account and...
SGMC Health Honors White with BEE Award
SGMC Health recognized Jessica White, patient care technician on 4 South, as the June recipient of the Being Extraordinary Everyday (BEE) Award, which honors non-nursing staff who demonstrate exceptional compassion, collaboration, and dedication to patient care.
ECU Health announces 2026 Board Quality Leadership Award winners
ECU Health Board Quality Leadership Award winners were recognized for delivering exceptional experiences and advancing patient outcomes.
Council Explores AI, Quality Improvement and Patient Safety to Advance Community Health
The MHA Council on Health Access and Community Impact held its final meeting of the program year June 4 to examine emerging opportunities and challenges shaping healthcare delivery and advancing community health.
OHSU advances massive leap in medical science with cellular therapies
Patients are benefiting from CAR-T to treat neurodegenerative diseases, cancer, lupus and other autoimmune conditions.
Most Patients Want Docs To Break Cancer News Directly, Not Through Portal Messaging
By Dennis Thompson HealthDay ReporterFRIDAY, June 25, 2026 (HealthDay News) — People are becoming more comfortable communicating with their doctor through clinics’ patient portals. Folks use the portals to ask their doc questions and even to review the results of recent medical tests. But there are ...
‘The Hot Zone’ led me to work with Ebola patients. Now I have mixed feelings about the book
“The reality of Ebola is simultaneously less sensational and far more challenging than most people imagine,” writes Krutika Kuppalli.
Clinicians are making more money despite stagnant reimbursement. Guess how?
Compensation for healthcare providers rose some 4.3% in 2025. The sobering news is that the gain owes more to heavier daily workloads than to bigger per-patient billings.
Sharonville mom raising money for UC Health's ICU patient program after she nearly died
It's been a year since a Sharonville mom suffered a medical emergency days after giving birth to her second child.
Baxter Health Heart and Vascular Clinic Welcomes Brandi Watson, APRN
Baxter Health is proud to welcome Brandi Watson, APRN, to the Baxter Health Heart and Vascular Clinic. Watson joined the team on May 15 and is currently accepting new patients. Watson brings more than 25 years of experience caring for some of the most critically ill patients. Much of her career has been spent in intensive care settings, where she learned to make fast, high-stakes decisions for patients whose lives depended on getting the right care at the right moment. That kind of experience, which is gained through years at the bedside, is exactly what heart and vascular patients need from a provider.
Serious statin side effects on muscles are extremely rare, new research confirms
Scientists created a new tool to help doctors predict a patient’s risk of severe muscle problems from taking a statin.
Health Watch: Scientists say animal therapy helps critically ill patients, prompting new legislation
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
$10M behavioral health unit opens at Milwaukee’s St. Francis Hospital
The renovated facility will serve 61 adults and children in need of behavioral health services, primarily assisting patients in southeastern Wisconsin. This expansion comes as Milwaukee faces challenges in keeping mental health facilities open
12 arrested in South Florida in nationwide investigation into $6.5B health care fraud
Investigators say Medicaid and Medicare thieves in South Florida bilked taxpayers for $27 million for everything from fake therapy to medical equipment patients never received. Officials seized the stolen taxpayer money from Key West to Fort Pierce.
Health Union Launches 2027 Innovation Suite, Pairing Community Leadership with AI to Accelerate Patient and HCP Connections
/PRNewswire/ -- Health Union, the pioneer in online health communities operating 125+ condition-specific sites reaching over 50 million patients and 9.5...
CHI Health debuts new orthopedic center in west Omaha
CHI Health is transforming its orthopedic care. On Wednesday, the organization broke ground on their new Lakeside Hills center. This will support patients from their initial diagnosis to recovery.
Psychiatrist says new UCSD Health policy hits hardest for working moms
Requirement mandates contracted psychiatrists spend at least 60% of their work hours seeing university patients
Assort Health scores $120M series C to scale voice AI agent platform for healthcare
Assort Health picked up $120 million in series C funding, hitting unicorn status, to fuel the company's work building out a voice AI agent platform for healthcare. | Assort Health has a large proprietary specialty dataset built on 190 million patient interactions, 62,000 care protocols and 1.6 million decision pathways.
Healthcare Providers Look Beyond Price To Deliver Better Value
A new approach to procurement promises to not just produce much-needed cost savings but also improve outcomes for patients.
New fraud charges include woman impersonating health care professionals, man billing for dead patient
Physicians East rolls out new electronic health record system, warns of possible delays
Physicians East is asking patients for patience as the healthcare provider transitions to a new electronic health record system.In a message to patients, Physic
Las Vegas woman accused of running illegal multi-million-dollar healthcare scheme in Pearland, prosecutors say
Marizel Yukee is accused of providing medically unnecessary allografts to patients while receiving kickbacks, according to the U.S. Attorney’s Office. Her case is one prosecutors are citing as part of a national crackdown on health care fraud.
New Patient Guidebook Helps Puget Sound Beneficiaries Navigate Their Health Care
MADIGAN ARMY MEDICAL CENTER, Joint Base Lewis-McChord, Wash. -- Great news for military communities and TRICARE beneficiaries across the Pacific Northwe...
SGMC Health Expands Access to Care with Pediatric and Family Visits at Primary Care Connell
SGMC Health is expanding access to care for families in South Georgia with the addition of pediatric services and family appointments at SGMC Primary Care – Connell, now welcoming patients of all ages—from newborns to seniors.
New Guidebook Helps Puget Sound Beneficiaries Navigate Their Health Care
Great news for military communities and TRICARE beneficiaries across the Pacific Northwest: navigating military healthcare just got easier. The recently released Puget Sound Patient Guidebook is a comprehensive resource designed for local TRICARE beneficiaries throughout the region. Inside, beneficiaries can find information on enrolling in the Defense Enrollment Eligibility Reporting System, understanding TRICARE plans, locating a Military Treatment Facility (MTF), scheduling appointments, accessing online services, ordering medications and much more.
Service meets science: Meet the first graduate of UAB’s Master of Science in AI in Medicine
UAB’s first graduate of the M.S. in AI in Medicine program blends clinical training with artificial intelligence, highlighting how physicians can use AI to reduce burnout, improve patient care and shape the future of healthcare.
France Identifies First Case of Ebola
The patient is a doctor who had traveled to the Democratic Republic of Congo, the health ministry said. Workers are racing to trace those who may have had contact.
Assort Health Raises $120 Million Series C to Scale Largest Deployment of AI Agents for the Patient Journey
/PRNewswire/ -- Assort Health, the most widely-used AI agents platform for the patient journey, today announced a $120 million Series C led by Menlo Ventures...
Penn LDI and Monogram Health Announce Second Research Partnership
The University of Pennsylvania’s Leonard Davis Institute of Health Economics and Monogram Health have launched a second research initiative, backed by a $600,000 gift, to improve care for patients…
The health and safety of NJ’s transgender community cannot wait
New Jersey must protect reproductive and transgender healthcare providers so that they can protect their patients.
France confirms first Ebola case in doctor returning from DR Congo
The patient is in isolation, following strict biosafety protocols to prevent risk of spread in France.
Podcasts are Changing the Doctor-Patient Dynamic. Is That a Good Thing?
The dynamic in the exam room is changing as more people show up ready to talk about what they’ve heard on podcasts.
The $50B rural health transformation fund is pushing many hospitals to shrink
To avoid losing funding, many states are pursuing proven cost-saving models, such as downsizing inpatient care, rather than novel, untested approaches, some experts say.