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What's fair game in politics?

Jim Lokay discusses the controversy over Vivek Ramaswamy's attack ad involving his opponent Amy Acton's estranged mother, plus how affordability arguments are shaping the last week of the midterm campaign with Andrew Donaldson of Ordinary Times.

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Oct 25 • 9:08 PM EDT • Politics • fox5dc.com
Cubs Trade Of Edward Cabrera An Early Lose-Lose Deal

A high-stakes gamble for Edward Cabrera backfired in Chicago as the right-hander's metrics plummeted, leaving the North Siders searching for answers amidst a looming rotation crisis.

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Oct 25 • 8:39 PM EDT • Sports • sports.yahoo.com
Politics Unplugged (Full Episode) Oct. 25, 2026

On this week's episode of Politics Unplugged, host Dennis Welch and a panel break down Arizona's election landscape one week out: pessimistic voter mood, suppressed independent turnout, lagging GOP enthusiasm, and Democrats gaining ground. They discuss Elon Musk's late spending in competitive House races and debate the impact of big money flooding the state. The show also covers a widely condemned Ohio attack ad by Vivek Ramaswamy that weaponizes a rival's childhood abuse—drawing praise from Trump and Vance but bipartisan outrage.

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Oct 25 • 8:31 PM EDT • Politics • azfamily.com
Four Positives From Frustrating Start To New Orleans Pelicans Season

These are some of the biggest positives to take away from the first few games of the New Orleans Pelicans' season.

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Oct 25 • 8:20 PM EDT • Sports • sports.yahoo.com
Local business expert recommends reporting scams via BBB scam tracker

The Better Business Bureau warned the public about phishing scams and advised consumers to regularly check their bank and credit card statements to identify fraudulent activity.

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Oct 25 • 8:08 PM EDT • Business • yahoo.com
Local business expert recommends reporting scams via BBB scam tracker

The Better Business Bureau warned the public about phishing scams and advised consumers to regularly check their bank and credit card statements to identify fraudulent activity.

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Oct 25 • 8:08 PM EDT • Business • fourstateshomepage.com
Claude AI accessed publicly available Georgia voter data, Anthropic confirms

Officials said the AI bot accessed publicly available voter data through the state's data hub but did not access voter files or Georgia's voter registration system.

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Oct 25 • 8:00 PM EDT • Business • foxbusiness.com
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Global Scientist Mobility: Redrawing the Innovation Map

Global scientist mobility patterns reveal how knowledge networks evolve. Learn why policy must shift from attracting talent to enabling circulation.

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Oct 25 • 8:00 PM EDT • Science • weforum.org
Innovative food processing technique boosts Nebraska companies, educational outreach

Leadership and strategic visioning by Mary-Grace Danao, research associate professor in the Department of Food Science and Technology and the Department of Biological Systems Engineering, has helped position the University of Nebraska–Lincoln at the forefront of high pressure processing-focused food safety research in partnership with private industry.

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Oct 25 • 8:00 PM EDT • Science • news.unl.edu
Decarbonizing Manufacturing Supply Chains: C-Suite Guide

Decarbonizing manufacturing supply chains guide for executives. Strategic insights on reducing carbon emissions while driving business growth.

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Oct 25 • 8:00 PM EDT • Business • weforum.org
Johnson & Johnson Deepens Hong Kong Commitment with Strategic Partnership to Accelerate Healthcare Innovation

Johnson & Johnson Deepens Hong Kong Commitment with Strategic Partnership to Accelerate Healthcare Innovation

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Oct 25 • 8:00 PM EDT • Health • biopharmaapac.com
Phantom Blade Zero review: dark wuxia martial arts masters with an apprentice's execution

S-Game's Unreal Engine 5 'kungfupunk' debut can't help but get tangled in frustrating design choices.

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Oct 25 • 8:00 PM EDT • Technology • creativebloq.com
2026 KlarText Prize for Science Communication: Klaus Tschira Foundation Honors Seven Researchers

What exactly did you do in your doctoral dissertation? The Klaus Tschira Foundation honors the most compelling answers to this question with the KlarText Prize for Science Communication. On Octobe ...

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Oct 25 • 8:00 PM EDT • Science • chemeurope.com
Probi and Symrise spotlight new clinical evidence at SupplySide Global

At SupplySide Global 2026, Symrise and Probi present new clinical findings for skin radiance and digestive health alongside a stable probiotic designed to broaden formulation options for brands

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Oct 25 • 8:00 PM EDT • Health • nutraceuticalbusinessreview.com
"Tomb Raider: Legacy of Atlantis" 30th Anniversary Trailer

A new trailer is out for “Tomb Raider: Legacy of Atlantis,” the reimagining of the original 1996 first “Tomb Raider” game. Created in Unreal Engine 5, it offers fresh visuals, skill trees, and an expanded Atlantis story that will tie in the various eras of Lara Croft together. As Lara, harness your wits and athleticism […]

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Oct 25 • 7:48 PM EDT • Technology • darkhorizons.com
Immediate Takeaways from Packers Frustrating Week 7 Loss in Detroit

The Green Bay Packers stood no chance of overcoming missed field goals, a stagnant ground game, and inexplicable officiating blunders.

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Oct 25 • 7:47 PM EDT • Sports • sports.yahoo.com
Taylor Swift's Trademark Battle Over 'The Life of a Showgirl' Faces Legal Setback
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Oct 25 • 7:45 PM EDT • Entertainment • yahoo.com
Australian politicians pay tribute to wounded lawmaker

Australia's prime minister and fellow parliamentarians led sombre tributes Monday to "beacon of decency" and colleague Helen Haines, who remains in hospital after being struck by a car outside her off...

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Oct 25 • 7:40 PM EDT • Politics • yahoo.com
Wizards rule out AJ Dybantsa for fourth-straight match

The NBA world will have to wait another night to see AJ Dybantsa's NBA debut.

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Oct 25 • 7:39 PM EDT • Sports • sports.yahoo.com
How Obama and Trump Made their Cases in Dueling Midterm Speeches

At rallies this weekend, Mr. Obama and Mr. Trump delivered two starkly contrasting pitches, differing in style and substance.

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Oct 25 • 7:35 PM EDT • Politics • nytimes.com
Thousands protest in Prague against public media funding reforms

Demonstrators allege Prime Minister Andrej Babis and his coalition's proposed reforms pose a threat to press freedom.

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Oct 25 • 7:29 PM EDT • Politics • aljazeera.com
Kyle Larson’s Championship Moment Comes at Talladega

Conquering his drafting-track demons, Larson surged from mid-pack chaos to secure a historic Hendrick 1-2 finish, building a massive points cushion that places the title within reach

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Oct 25 • 7:08 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
“Odegaard was outstanding” but Merson was less complimentary about Gyökeres

Paul Merson has delivered contrasting verdicts on two Arsenal players following Saturday’s comfortable 2-0 victory over Everton, singling out Martin Ødegaard for praise while questioning Viktor Gy�...

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Oct 25 • 7:00 PM EDT • Sports • sports.yahoo.com
9th Circuit panel questions basis for feds' request to block 20,000 California ballots

Two judges questioned the Justice Department's lawyer about how the Trump administration's position squared with the law.

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Oct 25 • 6:54 PM EDT • Politics • latimes.com
West Louisville business transforms into soul food restaurant, arcade
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Oct 25 • 6:47 PM EDT • Business • whas11.com
Judges skeptical of Trump administration effort for force California to set aside mail ballots

A three-judge US Circuit Court of Appeals panel expressed significant skepticism Sunday over the Justice Department’s desire to inject itself into California’s midterm vote-counting process by forcing election officials to set aside the votes of suspected noncitizens who have been issued mail ballots.

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Oct 25 • 6:38 PM EDT • Politics • cnn.com
TMSM Weekly Recap: Star Wars Super Bowl, Cap Lifts Thor's Hammer, Halloweentown 5 and More

Missed anything? Here are the biggest Disney stories from October 18 to 24, from Star Wars Funday Football and Avengers: Doomsday to Halloweentown 5 and Gideon's new trading cards.

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Oct 25 • 6:24 PM EDT • Entertainment • themainstreetmouse.com
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WHO chief praises Korea's role in global health, vaccines and pandemic preparedness

Tedros Adhanom Ghebreyesus said that Korea's training hub and AI expertise can strengthen global health security and pandemic preparedness.

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Oct 25 • 6:00 PM EDT • Health • koreajoongangdaily.com
A Remarkable Place to Die: Trailer
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Oct 25 • 5:35 PM EDT • Entertainment • yahoo.com
Bengals Shut out in Disastrous First Half vs Ravens

The Cincinnati Bengals are off to a first half they’d like to forget. Cincy trails the Baltimore Ravens 13-0 in Baltimore.The story has been the Cincinnati Bengals’ defense which has been struggling against this Ravens offense.The Ravens got off to a hot start as Zay Flowers took a 48-yard pass to the house from backup […] The post Bengals Shut out in Disastrous First Half vs Ravens appeared first on HEAVY.

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Oct 25 • 5:33 PM EDT • Sports • sports.yahoo.com
Scientists trapped antimatter particle for months -- but studying it without blowing up lab was a challenge
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Oct 25 • 5:07 PM EDT • Science • nypost.com
Alaska Democratic Senate candidate Mary Peltola and her family suffer minor injuries in car crash

Peltola required medical attention after the accident, which happened when another vehicle crashed into the one transporting Peltola and her family, the campaign said.

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Oct 25 • 4:11 PM EDT • Politics • pbs.org
Liverpool working towards deal for star; could reach €90m

Liverpool are reportedly in the mix for a very in-demand France star. They’re working towards a deal and it’s one that could cost €90m.Liverpool are weighing up their transfer targets for the up...

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Oct 25 • 4:10 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
6 Essential Gadgets For Learning To Play Guitar

We've picked out some of the best gadgets to support the process of learning to play the guitar, including for timing, ear training, and song practice.

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Oct 25 • 4:02 PM EDT • Technology • bgr.com
NH candidates for governor, U.S. Senate, Congress clash over...

At a Manchester forum, New Hampshire candidates clashed over housing, energy, healthcare and other costs as affordability emerged as voters’ central concern. ...

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Oct 25 • 4:00 PM EDT • Politics • unionleader.com
Tampa technical institute expands bilingual health care career training

Aguilas International Technical Institute has opened a larger Tampa facility, expanding bilingual career training as health care demand grows locally.

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Oct 25 • 3:57 PM EDT • Health • baynews9.com
Primark's Business Doesn't Make Sense

In a world where fast fashion giants like Shein, Zara, and H&M drop thousands of new styles every day — and rake in billions through e-commerce — Primark is doing the unthinkable: thriving with zero online shopping. So what gives?*Want to Know the 5 Trends Changing Modern Retail? Find Out Here:* 🔗 https://clickhubspot.com/d13ac2In this video, we take you inside Primark’s weirdly brilliant business model — a model that’s stuck in the past on purpose. From warehouse optimization and floor-ready freight shipments to why the pandemic didn’t push them online, we unpack how this low-cost retail giant has managed to defy digital norms… and make it work.This isn’t just about one brand. It’s a story about modern retail expectations — and what it actually takes to meet (or reject) them.Subscribe to The Hustle:🔗 https://clickhubspot.com/vu3lGet the 5-minute newsletter keeping 2M+ innovators in the loop🔗 https://clickhubspot.com/3klnAbout HubSpot: HubSpot is a customer platform that provides education, software, and support to help businesses grow better. The platform includes marketing, sales, service, commerce, operations, and website management products that start free and scale to meet our customers’ needs at any stage of growth. Today, thousands of customers around the world use HubSpot’s powerful and easy-to-use tools and apps to attract, engage, and delight customers.#TheHustle #HubSpot

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Oct 25 • 3:31 PM EDT • Business • finance.yahoo.com
Rep. Carbajal Meets with Cottage Health’s Head Honchos in Santa Barbara as They Brace for ‘Big Beautiful Bill’ Impacts

Trump’s bill expected to leave close to 40,000 Central Coast residents without health coverage, another 37,000 with higher premiums, and a roughly $40 million initial impact on Cottage.

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Oct 25 • 3:30 PM EDT • Health • independent.com
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Big Las Vegas show closures mark a transitional time for Strip entertainment

The culture of Las Vegas is inextricably linked to the artists and technicians behind the Strip’s vibrant live entertainment industry, so any time a show closes

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Oct 25 • 3:30 PM EDT • Entertainment • cdcgaming.com
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Utah business, government leaders deepen connections in Ireland

Utah Gov. Spencer Cox met with Irish Prime Minister Micheál Martin on Wednesday amid a trade mission organized by World Trade Center Utah.

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Oct 25 • 3:30 PM EDT • Business • ksl.com
Bayern beat Freiburg to reclaim top spot after Kompany illness

Bayern Munich reclaimed top spot in the Bundesliga with a 3-1 win at Freiburg on Sunday, days after coach Vincent Kompany was hospitalised when he collapsed at training.With coach Kompany still in hospital after collapsing on Friday, Englishman Danks was in the dugout.

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Oct 25 • 3:11 PM EDT • Sports • sports.yahoo.com
Halloween evolved as a Frankenstein of cultural celebrations

The holiday has origins in Celtic, Roman and Catholic festivals and feasts, and mixed with other traditions as it spread.

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Oct 25 • 3:00 PM EDT • Entertainment • theshorthorn.com
Queen of Halloween Heidi Klum teases costume with mysterious image

“What’s my costume?,” the model asked fans alongside a strange close-up photo.

yahoo.com logo
Oct 25 • 2:37 PM EDT • Entertainment • yahoo.com
Heidi Klum frightens fans, teases Halloween costume with bizarre close-up of strange prosthetic

The Queen of Halloween herself Heidi Klum is offering fans a first look at this year’s Halloween costume. As usual, it involves some pretty bizarre prosthetics.

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Oct 25 • 2:37 PM EDT • Entertainment • ew.com
Three Premier League talking points

Michael Carrick was pushed to the brink of the sack by Manchester United's latest debacle on Sunday.AFP Sport looks at three talking points from the weekend's action: Walls closing in on Carrick Michael Carrick's future as Manchester United boss was already hanging by a thread before Bournemouth inflicted what is likely to be a brutal last act for the former England midfielder at Old Trafford.

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Oct 25 • 2:36 PM EDT • Sports • sports.yahoo.com
Nigeria widens hunt for possible Ebola cases

Nigeria has widened a hunt for potential Ebola cases, with an additional nine contacts traced, health authorities said Sunday.The initial 44 contacts were health care workers, while the additional nin...

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Oct 25 • 2:26 PM EDT • Health • yahoo.com
‘There's a risk we do have a disconnect’: Business on Australian Labor

Chamber of Commerce CEO Andrew McKellar appears to suddenly be everywhere, all at once.

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Oct 25 • 2:15 PM EDT • Business • politico.com
Scientists Develop a Clever New Way To Kill Cancer Cells From the Inside

Scientists have developed an experimental strategy that exploits a chemical byproduct of cancer cells to produce anticancer drugs directly inside them. Scientists in Japan have developed an experimental method that uses a chemical produced by cancer cells to manufacture anticancer drugs directly inside them. The approach relies on carbon monoxide, a toxic gas that certain

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Oct 25 • 1:45 PM EDT • Science • scitechdaily.com
Uganda tightens Ebola border controls and requires returnees from Congo to pay for quarantine

Uganda is reinforcing existing border controls requiring citizens returning from Congo to undergo 21 days of quarantine at their own expense, the Health Ministry said Sunday, as investigators examine how a woman who traveled from Uganda to Nigeria contracted Ebola.

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Oct 25 • 1:45 PM EDT • Health • seattletimes.com
Uganda tightens Ebola border controls and requires returnees from Congo to pay for quarantine

Uganda is reinforcing existing border controls requiring citizens returning from Congo to undergo 21 days of quarantine at their own expense, the Health Ministry said Sunday, as investigators examine how a woman who traveled from Uganda to Nigeria cont...

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Oct 25 • 1:44 PM EDT • Health • abcnews.com
Schefter: Seahawks among teams ‘expected to consider’ Jonathan Taylor trade

The Seahawks are “pondering” adding Taylor in hopes of saving their run game.

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Oct 25 • 1:32 PM EDT • Sports • sports.yahoo.com
☹️ Negative (-10%)
Projections for Cleveland Guardians’ Arbitration Eligible Players

The Cleveland Guardians have several key players arbitration-eligible this offseason.

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Oct 25 • 1:30 PM EDT • Sports • sports.yahoo.com
BCM hosting special Nov. 13 show for America 250

BRISTOL — In partnership with The Crooked Road: Virginia’s Heritage Music Trail, Mountain Empire Children’s Choral Academy, and Theatre Bristol, the Birthplace of Country Music Museum is bringing together an

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Oct 25 • 1:30 PM EDT • Entertainment • therogersvillereview.com
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Nico Williams publicly disavows his agent over Barcelona transfer claims

Barcelona’s long and drawn-out pursuit of Nico Williams has become one of the more familiar sagas of recent transfer windows.The Athletic Club winger ultimately opted to stay at San Mames, snubbing ...

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Oct 25 • 1:17 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Argentina Folk Sounds, Controversy: Milo J, Cazzu, Broke Carey

Milo J, Cazzu, and more stars are embracing music and traditions of the Argentine countryside and sharing their history with the world.

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Oct 25 • 1:09 PM EDT • Politics • rollingstone.com
How Argentina’s Folk Sounds Are Shaping a Generation’s Politics and National Pride

Milo J, Cazzu, and more stars are embracing music and traditions of the Argentine countryside, staving off pop homogenization and sharing their history with the world

yahoo.com logo
Oct 25 • 1:09 PM EDT • Politics • yahoo.com
Business People: Evereve names industry vet Sarah Clary to advise on creative

RETAIL Evereve, an Edina-based women’s fashion retailer, announced it has named Sarah Clary as advisory chief creative officer. Clary previously has led creative direction campaigns and brand strategy for Hill House Home, Veronica…

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Oct 25 • 1:01 PM EDT • Business • twincities.com
Oregon fires offensive coordinator Drew Mehringer after team scored just 10 points in loss to Illinois

Saturday's loss marked the third straight game in which Oregon scored under 20 points.

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Oct 25 • 12:57 PM EDT • Sports • sports.yahoo.com
Blanche says Trump isn’t trying to meddle with Alaska election results by suing over Senate race

WASHINGTON (AP) — Attorney General Todd Blanche on Sunday defended the Trump administration's lawsuit to block certification of Alaska's Senate results if Repub

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Oct 25 • 12:51 PM EDT • Politics • wtop.com
Blanche says Trump isn't trying to meddle with Alaska election results by suing over Senate race

Attorney General Todd Blanche is defending the Trump administration’s lawsuit to block certification of Alaska's Senate results if incumbent Republican Dan Sullivan loses the race.

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Oct 25 • 12:49 PM EDT • Politics • news4jax.com
Blanche says Trump isn't trying to meddle with Alaska election results by suing over Senate race

Attorney General Todd Blanche is defending the Trump administration’s lawsuit to block certification of Alaska's Senate results if incumbent Republican Dan Sullivan loses the race.

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Oct 25 • 12:49 PM EDT • Politics • ksat.com
😱Fans back Carrick: How the United players left

Today, Manchester United suffered another crushing defeat, losing 0-3 to Bournemouth at Old Trafford. There was plenty of talk during the week about the rift between the players and Michael Carrick, p...

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Oct 25 • 12:44 PM EDT • Sports • sports.yahoo.com
Epic CEO Tim Sweeney lambasts “abhorrent” Steam AI Disclosure Policy claiming labels double as “political statement”

Epic Games CEO Tim Sweeney called Steam’s AI disclosure policy abhorrent, arguing that it exposes developers to backlash from anti-AI detractors. Valve has implemented and updated the policy since 2024, which states that AI-generated content, including artwork, text, music, and assets, excluding assistant tools, requires formal disclosure.

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Oct 25 • 12:31 PM EDT • Technology • notebookcheck.net
Lakers 1st-Round Draft Pick Floated as Trade Piece

The Los Angeles Lakers are off to a fast start. Could it be time to weigh trading away some young pieces to boost the rotation? The post Lakers 1st-Round Draft Pick Floated as Trade Piece appeared first on HEAVY.

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Oct 25 • 12:29 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Bloomington business continues to blossom

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Oct 25 • 12:11 PM EDT • Business • insideindianabusiness.com
😐 Neutral (0%)
Is having urine the color of Mountain Dew normal?

A Trump administration doctor says neon yellow urine is normal because of diets consisting entirely of meat and fermented foods. Here’s what experts say

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Oct 25 • 12:00 PM EDT • Health • health.yahoo.com
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Americans have a grief problem we still call a mental health problem

OPINION — Americans have become much better at talking about mental health. We have learned words such as trauma, post-traumatic stress disorder, depression, anxiety, burnout, compassion fatigue and moral injury. That vocabulary matters.

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Oct 25 • 12:00 PM EDT • Health • yourvalley.net
In Texas Senate Race, Talarico Leans Into Growing Rivalry With Elon Musk

On the trail, James Talarico, the Democratic Senate nominee, has increasingly gone after Mr. Musk, a critic of his who has given big to a group aligned with the Republican candidate, Ken Paxton.

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Oct 25 • 11:53 AM EDT • Politics • nytimes.com
Game Time Thread: Juventus vs. Lecce

MATCH INFO When: Sunday, Oct. 25, 2026. Where: Stadio Via del Mare, Lecce, Italy. Official kickoff time: 6 p.m. local time in Italy and across Europe, 8 p.m. in the United Kingdom, 1 p.m. Eastern time, 12 p.m. Central time, 10 a.m. Pacific time. (Please note that the fall time change in Italy goes into effect on Sunday, […]

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Oct 25 • 11:45 AM EDT • Sports • sports.yahoo.com
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals

Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.

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Oct 25 • 11:30 AM EDT • Health • fiercebiotech.com
Nonprofit organizes ‘silkies’ hike to support military members’ mental health

During the hike, participants wore military short-shorts known as “silkies” as part of the event’s tradition to foster connection.

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Oct 25 • 11:27 AM EDT • Health • wpxi.com
California election officials frustrated, rattled by DOJ demand to sequester 'noncitizen' ballots

The administration has insisted that immigrants voting is a major problem nationwide, when in fact it is quite rare, as even its own investigations have shown.

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Oct 25 • 11:17 AM EDT • Politics • pbs.org
Syria’s Democratic Transition: Building Institutions Alongside Political Competition

Syria’s post-Assad transition has revived debate over when to legalize political parties. Parties are essential to political competition,

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Oct 25 • 11:16 AM EDT • Politics • fairobserver.com
Mystery Ohio news site boosting Ramaswamy's Amy Acton ad tied to California GOP non-profit

As Ohio Republican gubernatorial candidate Vivek Ramaswamy came under fire for releasing an attack ad featuring his Democratic competitor Amy Acton's estranged mother, a mysterious news site was runni...

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Oct 25 • 11:08 AM EDT • Politics • yahoo.com
On Christ the King and the idolatry of politics

Editor’s note: This homily was preached on the feast of Christ the King (Extraordinary Form), October 25, 2026, at the Church of the Holy Innocents, New York City. In the calendar of the Usus Antiquior, […]

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Oct 25 • 11:00 AM EDT • Politics • catholicworldreport.com
Seattle Mariners Rumors: Zach Neto Gaining Traction as Possible Target

The M's certainly have a need for what Neto can provide.

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Oct 25 • 11:00 AM EDT • Sports • sports.yahoo.com
Stateliner Pride on Display: Phillipsburg Band and Alumni Unite at Halftime

Phillipsburg’s Stateliner band and alumni joined for a halftime performance celebrating school tradition, pride and community at Friday’s football game.

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Oct 25 • 11:00 AM EDT • Entertainment • tapinto.net
Micron Just Revealed a New Business Strategy. That Change Makes It a Screaming Buy.

Micron is changing more toward contracts, rather than letting the open market dictate pricing.

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Oct 25 • 10:51 AM EDT • Business • finance.yahoo.com
University of Rochester Medicine Home Healthcare holds inaugural Hospice 5K

13WHAM ABC Rochester provides local news, weather forecasts, traffic updates, health reports, notices of events and items of interest in the community, local sports and entertainment programming for Rochester and nearby towns and communities including Greece, Victor, Pittsford, Penfield, Henrietta, Webster, Irondequoit, Fairport, Chili, Gates, Rush, Wheatland, Canandaigua, Farmington, Spencerport and Hilton.

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Oct 25 • 10:44 AM EDT • Health • 13wham.com
After Fighting in Gaza and Battling PTSD, Shahar Varon Seeks a Voice In Israel's Mental Health Future

Soldiers and others suffering from post-traumatic stress disorder […]

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Oct 25 • 10:41 AM EDT • Health • themedialine.org
9 Cool Camping Features Built Into Oliver Travel Trailers (And 3 You Can Add Yourself)

The utility you can get with an Oliver Travel Trailer these days will surely enhance your next camping trip, but there is even more than meets the eye.

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Oct 25 • 10:30 AM EDT • Technology • slashgear.com
NFL Trade Deadline Could Dramatically Change The AFC South Landscape

With top stars from the Titans, Colts, and Jaguars hitting the trade block, Houston’s rivals could strip their rosters of veteran talent to fuel a mid-season rebuild.

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Oct 25 • 10:22 AM EDT • Sports • sports.yahoo.com
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The science and politics behind the panic over ultraprocessed foods

The very definition of ultraprocessed is highly contested.

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Oct 25 • 10:19 AM EDT • Science • wfla.com
Oprah on the Health Metric We Should All Be Tracking

“These facts are a wakeup call for all of us to get serious about our heart health.”

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Oct 25 • 10:10 AM EDT • Health • oprahdaily.com
Instacart Stock What Health Benefits Deal And $5 Million Settlement Mean

Instacart parent Maplebear has agreed to a US$5,000,000 settlement with U.S. authorities over past PERM hiring practices and has been selected by True Rx Health Strategists to power an employer funded healthy food benefit through Instacart Health Fresh Funds starting in 2027. The True Rx program positions Instacart within pharmacy benefit design and ties employer spend directly to clinically supervised food choices. The settlement adds compliance obligations, policy changes and monitoring...

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Oct 25 • 10:08 AM EDT • Health • finance.yahoo.com
After long, strange trip, Compass CEO nears launch of psilocybin pill

Compass Pathways is on the cusp of FDA approval for a proprietary version of psilocybin — the active drug in magic mushrooms.

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Oct 25 • 10:07 AM EDT • Business • businessinsider.com
17 Celebrity Transformations That Left Fans Doing A Double Take

From Avril Lavigne's “soft makeup era” to JoJo Siwa’s “clean girl” aesthetic, these wild celebrity transformations will leave you gagged.

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Oct 25 • 10:00 AM EDT • Entertainment • yahoo.com
Stop Chasing Views: How 87% of Creators Are Using AI to Build Real Businesses Beyond Social Media

87% of creators say AI is growing their business. Here's how creators trade social media algorithms for owned commerce and real enterprises.

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Oct 25 • 10:00 AM EDT • Business • inc.com
Manchester United vs Bournemouth: Live updates from Old Trafford

Under-fire Manchester United manager Michael Carrick is under enormous pressure heading into today’s Premier League clash with Bournemouth on the back of a seven-game run without a win.The boss has ...

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Oct 25 • 10:00 AM EDT • Sports • sports.yahoo.com
Maliek Collins agrees to terms on contract extension

Maliek Collins to remain in Cleveland for two additional years

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Oct 25 • 9:54 AM EDT • Sports • sports.yahoo.com
Investment driving growth at NWS Crane

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Oct 25 • 9:53 AM EDT • Business • insideindianabusiness.com
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Former Coach Urges Vikings to Blow Up Kyler Murray Experiment; Trade for… Kirk Cousins?

Jon Gruden has an insane trade idea for the 5-0 Minnesota Vikings and involves a quarterback change that nobody would see coming...

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Oct 25 • 9:51 AM EDT • Sports • sports.yahoo.com
Fernandes dropped: Man United name team to face Bournemouth

Manchester United have named their team to face Bournemouth in the Premier League, with captain Bruno Fernandes dropped from the side.Fernandes has been named among the substitutes at Old Trafford, in...

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Oct 25 • 9:37 AM EDT • Sports • sports.yahoo.com
'All INdiana Politics': Engling, Ballard clash over restoring credibility to Indiana Secretary of State Office

INDIANAPOLIS — On Sunday’s edition of “All INdiana Politics,” Government Reporter Garrett Bergquist sat down with two candidates who are running for secretary of state, Republican Max Engling and independent Greg Ballard. Both candidates outlined contrasting approaches to restore credibility to an office plagued by controversy under outgoing Secretary Diego Morales. They both presented different […]

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Oct 25 • 9:30 AM EDT • Politics • wishtv.com
Argument over purchase turns physical; suspect pulls gun at South Side business

KABB Fox News 29 San Antonio provides local news, weather forecasts, traffic updates, investigations, notices of events and items of interest in the community, sports and entertainment programming for San Antonio and nearby towns and communities in South Central Texas, including Bandera, Boerne, Carrizo Springs, Castroville, Cibolo, Converse, Crystal City, Cuero, Del Rio, Devine, Eagle Pass, Floresville, Fredericksburg, Goliad, Helotes, Hondo, Kerrville, Live Oak, New Braunfels, Pearsall, Pleasanton, Poteet, Poth, Sabinal, San Marcos, Seguin, Schertz, Somerset, Universal City, Uvalde, Windcrest.

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Oct 25 • 9:27 AM EDT • Business • foxsanantonio.com
Argument over purchase turns physical; suspect pulls gun at South Side business

WOAI NBC News Channel 4 San Antonio provides local news, weather forecasts, traffic updates, investigations, and items of interest in the community, sports and entertainment programming for San Antonio and nearby towns and communities in South Central Texas, including Windcrest, Uvalde, Universal City, Somerset, Seguin, Schertz, San Marcos, Sabinal, Poth, Poteet, Pleasanton, Pearsall, New Braunfels, Live Oak, Kerrville, Hondo, Helotes, Goliad, Fredericksburg, Floresville, Eagle Pass, Devine, Del Rio, Cuero, Crystal City, Converse, Cibolo, Castroville, Carrizo Springs, Boerne, Bandera.

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Oct 25 • 9:27 AM EDT • Business • news4sanantonio.com
Physician Mental Health and Health System Privacy: Why Doctors Avoid Their Own EHR

In most organizations the default access model was built for patient care, not for protecting colleagues. A nurse on another unit, a resident who rotated with them, a department administrator: any of them may technically be able to open the record, even when policy says they should not.

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Oct 25 • 9:21 AM EDT • Health • medcitynews.com
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Taylor Dayne Trades L.A. for Coastal Sanctuary After Health Battle

The pop icon has traded the hustle of Los Angeles for a new life in Santa Barbara after recovering from a harrowing battle with colon cancer.

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Oct 25 • 9:13 AM EDT • Health • realtor.com
Calvert liquor store gets license transfer; other business fined

New management will be taking over a liquor store in Dunkirk sometime in November.

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Oct 25 • 9:05 AM EDT • Business • somdnews.com
Guardians Middle Infielder is a Prime Trade Candidate

The Cleveland Guardians, fresh off an ALCS appearance, will be facing several tough decisions next season regarding their lineup. The 85-win team won their division and looks poised to repeat next year, but they face an enviable dilemma. What do they do with their influx of top, young talent, and how do they find them …

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Oct 25 • 9:00 AM EDT • Sports • sports.yahoo.com