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Scientists may be overestimating the amount of microplastics in the environment – and the culprit is lab gloves
Tiny particles from certain lab gloves look like microplastics, and they can contaminate samples, new study finds.
Is Big Tech Facing a Big Tobacco Moment?
Back-to-back courtroom losses have put technology giants, including Meta and Google, in uncertain territory as they face lawsuits and bans on teen users.
What To Order At A Business Dinner, According To An Etiquette Expert
Business dinners are all about chatting to connections and making a good impression, so there are certain foods to avoid, according to an etiquette expert.
New bill could shield small business payroll cash, curb bank runs and aid community banks
A bipartisan group of lawmakers has reintroduced legislation that would expand federal deposit insurance coverage for certain bank accounts.
Students ‘Surge’ with fun at local entertainment center
Have you ever wanted to visit an arcade, a restaurant and a bowling alley all in one place? Surge Entertainment by Drew Brees combines all three in same building, along with more activities including laser tag and sports simulators. While the venue offers variety, its attempt to do everything at once leaves certain areas underdeveloped,...
Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
Seven foods to add to your diet for better hormone health, according to a doctor
You may have heard about hormone-balancing diets and certain dishes to tweak hormone levels. But is there such a thing as a hormone-balancing food?
Funding Uncertainty Has Consequences
We're asking the U.S. government to release holds on Congressionally-appropriated funding for scientific research, education, and critical activities at the earliest possible time.
Marathon has sold 1.2M copies across Steam, PS5, and Xbox
Alinea Analytics estimates show that Marathon has generated gross revenues of $55M via 1.2M copies sold on Steam, PS5, and Xbox: Looking at the split between Steam, PS5, and Xbox, Steam is clearly the main platform for Marathon, accounting for a little under 70% of the audience (800K copies sold). Meanwhile, PS5 takes about 19% (217K) and Xbox (including console, PC, and cloud) accounts for a bit over 11% or 133K. Marathon is technically a first-party Sony title, so seeing the home console struggle to break 20% of the volume is a notable data point for the ongoing platform-agnostic debate. PlayStation Studios online games will almost certainly continue being multiplatform (despite Sony reportedly pulling back on PC releases). Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe As for Marathon, the consensus among hardcore players who pushed through the awkward onboarding phase – myself included – is that it’s fantastic. The gunplay, aesthetic, and presentation are among the best in the shooter genre. A great game doesn’t always equal an immediate hit, though, as shown by our estimates. Things are looking lukewarm right now. But this might be one of those marathon-not-a-sprint situations. Had to, didn’t I? Why wasn’t Marathon a hit on the same level as Arc Raiders? One topic that came up in a lot of conversations at GDC this year was why Marathon hasn’t hit the same stratosphere as Arc Raiders. On paper, they’re both extraction shooters, and Marathon has the Bungie pedigree – the house that built the gold standard for gunplay in Halo and Destiny. Marathon’s neon-futuristic aesthetic also distinguishes itself from the gritty realism of Tarkov or the post-apocalyptic hope of ARC Raiders. But vibes can only get you so far for first impressions if the onboarding feels like a brick wall. Marathon is a sweaty PvP-focused experience with a first-time user experience and UI that I can only describe as dreadful. Players are dropped into a complex ecosystem where the UI, though visually striking, is functionally uninformative, forcing users to manually hover over nondescript, identical icons just to identify basic gear or weapon mods. This lack of clarity is compounded by punishing mechanics like a severe heat gauge for movement and a scarcity of vital resources, all without a clear tutorial or a low-stakes mode to learn the ropes. Most people – even top streamers and veteran shooter players – have no idea what’s going on in Marathon at first. Arc is on the complete other end of the spectrum. As we covered here and here, Arc Raiders offers a more collaborative, approachable loop where players often work together toward shared goals. And the objectives are instantly clear. To many players, this contrast only emphasised Marathon’s issues, especially during the testing period. Players understand the Arc Raiders loop within 30 minutes, while Marathon acts as a massive filter, chewing up newcomers and spitting them out before they can experience the depth of Bungie’s signature gunplay. What I’m getting at here is that the poor first-time user experience of Marathon’s Server Slam likely stifled launch sales, while the opposite was true for Arc. Let’s look at the pre-launch copies sold for each game during their respective Server Slams (launch-aligned) : Looking at the trajectory: Arc Raiders saw a massive 80% jump in copies sold during its three-day Server Slam (day -13 to -11). Players jumped in, realised the water was fine, and immediately opened their wallets. Marathon, meanwhile, saw a 49% increase in the four days following its Slam (Day -7 to -3). At the time of each game’s respective launch, Arc Raiders had nearly double the Steam footprint of Marathon – and word of mouth only continued to grow. Bungie could have had more time to fix the onboarding process had the beta happened earlier. But Marathon launched three days after the beta finished. These factors limited the launch sales quite a bit, I reckon. Marathon has found a niche audience, though Despite the friction-heavy start, the data suggests that those who survived Marathon’s onboarding are loving life. We’ve been tracking cross-platform DAUs, and while there’s the expected post-launch leakage, many players are sticking with it. After peaking at 478K total DAUs on its first Saturday, Marathon has settled into a respectable rhythm, holding 345K DAUs as of yesterday and averaging 380K DAUs across the weekend. Steam continues to do the heavy lifting here, consistently accounting for the lion’s share of the daily players. Players have been putting in the hours, too: On Steam, Marathon’s average playtime has climbed to 27.8 hours, significantly outpacing the console averages on PS5 (16.5h) and Xbox (17.3h). Even more telling than the averages: 22% of the Steam audience has surged past the 50-hour mark, and nearly 7% have already logged over 100 hours. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe This data suggests that once the Bungie magic clicks, it hooks players deeper than the average extraction shooter. There’s also started to be a shift in the game’s discourse. Marathon launched as one of those games that’s cool to hate. But as Marathon’s 100-hour club grows, we’re seeing conversations around its mechanical merit outweigh the negativity. Several high-profile creators, who were initially vocal critics, have spent the last week coming around on the mechanical depth of the endgame. It’s a subtle but positive signal; the hate train is losing steam, and a new narrative about the game is emerging. Bungie faithfuls unite Another interesting metric in Marathon’s first few weeks is who, exactly, is playing. Bungie leans heavily on its prestige as the “makers of Halo and Destiny,” in its marketing, and that message has clearly hit the mark. On Steam, the gravity (hammer) of Bungie’s previous work is unavoidable. A staggering 78.2% of Marathon players also played Destiny 2. The trend carries across other platforms, with 74.2% of PS5 players and 82.7% of Xbox players also having played Destiny 2. The Halo legacy lives on, it seems. More on that in a bit. While Destiny 2 went free to play, these numbers still represent a high-intent migration of a fanbase that trusts Bungie’s specific brand of kinetic gunplay and cryptic world-building. The Xbox data adds another layer of legacy. About 85.7% of Marathon players on Xbox have played Halo Infinite, while over half of the Steam audience has spent time in Halo Infinite and 36.1% in the Master Chief Collection (a paid collection of the old Bungie-made legacy games). Interestingly, we see a 55.9% overlap with ARC Raiders on Steam. Overlap is even higher there on PlayStation (60.5%) and Xbox (66.5%). And there’s also significant crossover with Helldivers 2 on all platforms, too. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe Bungie has found some of its fans with Marathon, and the challenge now is keeping this engaged in a high-stakes PvP environment when they’ve spent the last decade primarily enjoying the power fantasies of PvE. On that note… Go the full 26 miles? Or cut and run? Time for some could’ve, should’ve, would’ve. These things would have improved Marathon’s performance at launch: A more robust onboarding process, perhaps in the form of a short single-player/PvE campaign. We know Bungie fans love this stuff. A traditional arena-based mode akin to Destiny’s Crucible could have been a bridge for the cautious players who’d have been otherwise deterred by the Server Slam. It’s also a great palate cleanser after getting merked. Introducing a dedicated PvE environment would have similarly diversified the conversation and lowered the barrier for the Bungie faithful who found the pure PvP extraction loop too abrasive. PvE is safer than PvP these days. There’s an argument that a thin PvE mode would have just felt like a budget Destiny, potentially hurting the brand more. But given how dire the FTUE is, I think it would have been a net positive. Any kind of tutorialised loop that demystifies the stakes, really. While there is merit in a studio sticking firmly to a singular creative vision, and going all in on the hardcore extraction loop. Less forgiving is the technical reality is that the user interface and first-time user experience (FTUE) were not at a commercial standard for launch. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe In a landscape where player time is oversaturated and the most contested currency, a flawed FTUE is a critical failure point. But it’s not all doom and gloom, as Marathon has an incredible, unique gameplay loop, suggesting that financial success is still attainable if Bungie can pivot effectively. Bungie and PlayStation now face a difficult strategic crossroads, though – one within a challenging games market. They could: Double down on Marathon with a long-term Rainbow Six Siege- or No Man’s Sky-style recovery plan, which is something I heard Last Stand Media’s Chris Maldonado mention last week. While this could be a sunk-cost fallacy in action, it could eventually yield the audience the game’s mechanical depth deserves. Shift focus toward the inevitable Destiny 3 or another project, mitigating the escalating opportunity cost and cutting their losses, so to speak. Doing both is an expensive proposition, given the high overhead and burn rate of operating out of Bellevue, Washington. With Sony recently demonstrating a lower threshold for underperforming studios and projects, the margin for error has vanished. Whatever happens, the next six months will determine whether Marathon becomes a cornerstone of Sony’s live-service portfolio or a cautionary tale of vision exceeding accessibility. I’m hoping it’s the former, because Marathon rocks. As always, hit subscribe to get updates on Marathon and other relevant games. Subscribe Want to get your hands on our data for yourself – for free? We’re offering a free trial of our platform for games companies. Send us a message here, or reply to this email, and we’ll set you up. The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]
Iran war starts to hit global economy, business surveys show
The Iran war is already taking a toll on major economies around the world, according to business surveys on Tuesday which showed how a surge in energy prices and rising uncertainty were dampening activity and pushing inflation expectations higher.
Age Comes for Us All—Even Politicians
Don’t look now, but the period from now through the 2028 presidential election will be a historic inflection point in our politics. We’ll see enormous generational change take place amid enormous uncertainty and volatility.
Holland & Knight Health Dose: March 24, 2026 | Insights
Congress faces a tight deadline on DHS funding and the SAVE Act as Easter recess nears, while healthcare hearings continue amid uncertainty.
Do you need political risk insurance? How to insure your business amid uncertainty
Political risk insurance took center stage earlier this month after vessels struggled to safely navigate the Gulf of Hormuz. But do you need it?
Public Health Alert For Ground Beef—‘Do Not Consume’
The U.S. Department of Agriculture’s Food Safety and Inspection Service issued a public health alert for certain ground beef products.
Eurozone, Asian Business Activity Slows as Iran War Ramps Up Uncertainty
The war has driven up energy prices and uncertainty, while a cooling of new orders points to longer-lasting harm if the conflict continues or escalates.
We disagreed on politics. We agreed on wine. That was enough.
At the Virginia Governor’s Cup Gala in Richmond earlier this month, a very dapper gentleman approached me and introduced himself. In his light-colored suit and bowtie, he looked very Southern in a classical sense, the sort of Virginia Gentleman you used to see south of the Rappahannock as recently as my college days. “I’m a longtime reader and fan of your writing, if not your politics,” he said. His comment was the proverbial iron fist in a velvet glove, simultaneously conveying praise and disapproval while establishing boundaries. Man, I wish we still discoursed like this instead of shouting bromides and insults to try and “own” our opponents with a funny meme and a furrowed brow. Subscribe “Well, we’ll always have wine to share together,” I said, and thanked him for his kind words. We clinked glasses, exchanged pleasantries about the delicious gold medal-winning wines being poured that evening, and went our separate ways. Our exchange reminded me that more unites us than divides us. Wine brings people together to share a meal and a few hours of joy despite our differences.1 That’s why I refer to the wine community — including readers and consumers — rather than the wine industry. Together, we are so much more than production, distribution and sales statistics. A few minutes later the evening’s awards ceremony began. Applause grew as the 12 winemakers who made the top-scoring wines for the Governor’s Case took the stage, including a loud cheer for Jonathan Wheeler of Trump Winery and his 2018 Blanc de Noir sparkling wine. All the winemakers on stage had reason to be proud, Wheeler perhaps more so. Trump Winery was the only winery to win six gold medals in the competition this year. (Wineries are limited to six entries.) Two of Wheeler’s ciders also won gold medals in a separate competition. When you cover the labels and take the sour taste of politics off your palate, the wines are pretty darn good.2 Then Gov. Abigail Spanberger, newly elected Democrat and Virginia’s first female governor, was introduced to great applause to announce which of the 12 wines had won the Governor’s Cup. She spoke for a few minutes about the importance of wine to Virginia’s economy and tourism and the international acclaim Virginia wine has received. Just two weeks earlier, she gave the Democrats’ response to Trump’s State of the Union speech, but this night wasn’t about politics. That didn’t stop several people in the crowd from speculating on the irony should she have to present the trophy to Trump Winery. In the end, Valley Road Vineyards was displayed on the screen behind Spanberger as the winning winery. Blue Bee Cidery in Richmond took top honors for that category. The crowd cheered a female governor presenting the state’s highest trophy to a female winemaker and then resumed the evening’s festivities, united by their mutual love of wine. A whiff of politics couldn’t dim the cheer of celebration and a community united by its love of wine. In Memoriam: Michel Rolland The global wine community lost a giant March 20, with the passing of Michel Rolland. He was 78. Rolland was the original “flying winemaker,” a globe-trotting consultant who helped Bordeaux regain its mojo in the 1970s and then shaped the rise of Napa Valley cult Cabernet as consultant to Simi, Harlan, Newton, Screaming Eagle, Araujo, Dalle Valle and other wineries. He was instrumental in Argentina’s rise to prominence and even had his own winery, Clos de los Siete, in a partnership with other wine families. Rolland’s career arc paralleled that of Robert Parker, the world’s most influential critic. Parker championed many of the wines Rolland consulted on, helping build his reputation and demand for his services. It also made him a target for Parker’s critics. As W. Blake Gray wrote on Wine-Searcher in his excellent tribute to Rolland: Rolland created the type of wines Parker loved: rich body, plenty of fruit, soft tannins. He sometimes faced the accusation of creating a generic international style of red wine, where the great wines he made in Argentina were indistinguishable from the great wines he made in France. Rolland chafed at that critique, as did many of his fans. He was credited with championing green harvesting and leaf pulling, as well as careful selection of grapes in the winery, practices we nearly universally think of today for high-quality winemaking. “Michel was an incredible innovator who changed how wine was made and how grapes were grown,” Napa Valley winemaker Aaron Pott wrote on Facebook. “His work has transformed the wine trade. He created new ways of looking at wine, tasting wine, evaluating ripeness and quality. … This was not just a man with a ‘style’ that he imposed on vineyards but a man that understood how to make great wine from great sites.” Rolland started his consulting company in 1973 in Libourne, in Bordeaux, with his wife, Dany. Both had graduated the year before from Bordeaux’s Institute d’Oenologie. The couple sold their majority share in the business in 2020, according to Wine Spectator. Over his career, Rolland reportedly worked with more than 100 wineries in 20 countries. He even made it to Virginia, where he consulted for Kluge Estate in the mid-2000s. (Kluge Estate is now Trump Winery.) Reader feedback, please! Last week, I did my first WineLine Live! with Dr. Laura Catena of Catena Zapata winery in Argentina. We enjoyed a fascinating discussion about her efforts to preserve the genetic heritage of old vineyards in Mendoza. I conceived of WineLine Live! for paid subscribers, as a thank you for your financial support. And while only a few people joined live, the video now has more views than I have paid subscribers, so I guess that’s pretty good. Even so, I’m considering opening future installments to anyone on Substack to reach a broader audience. So my questions to you: Should these be public? And what format do you prefer? Live gives a chat feature with the potential for viewers to interact with me and the guest, while a video post would just be that. Another alternative is a podcast, which would just be audio, without video of my chins. Please let me know in the comments. Leave a comment In the Glass A few wines I’ve enjoyed recently: Bonny Doon Vineyard Take Me to Your Liter, Le Cigare Volant, Red Wine of the Earth. 2023, Central Coast, CA. Blend of Grenache, Syrah Cinsaut and Petite Sirah. Delightful wine with expressive red fruit flavors, casual drinking. Doon lovers of a certain age will remember Randall Grahm’s Big House Red; this is more in that style than his original Le Cigare Volant, modeled after Chateauneuf du Pape. The liter bottle makes it an even better value. I see this online at about $15. Great value. Albert Bichot Bourgogne Pinot Noir Origines 2023. 13% - Textbook pinot noir and an excellent, affordable entry (regional) Burgundy. Wine Enthusiast Top 100 Wines of 2025. $24 at Total Wine & More. Loma Larga Pinot Noir 2021 “Coastal Cool Climate Wine”, Valle de Casablanca, Chile. An older sample, showing beautifully. Spicy and fruit forward. I’m seeing widely varied pricing online, from $18-$32. At the lower end, it’s a terrific value. 13.5% Dr. Loosen Riesling Dry 2016, Mosel, Germany. Found this “in the stack.” And it stacked up well, shedding some of its youthful acidity for opulent Riesling character, including a hint of the mineral oil older Riesling often features. A great value, as I’m seeing it as low as $14 online. 12% abv. Red Tail Ridge Blau Franc Blend 2024, Sans Oak, Finger Lakes. 13.4% abv. The name is a neat portmanteau of Blaufrankisch and Cabernet Franc, thus Blau Franc. The blend is 50-50, no oak involved. The Blau dominates on the palate, with the spicy caraway seed (think New York deli rye bread). The Franc adds body. The result is juicy, energetic and joyful. Sokol Blosser Estate Rosé of Pinot Noir 2025, Dundee Hills, Willamette Valley, Oregon. This first rosé of 2025 was a welcome respite to our cold, snowy winter here in the Mid-Atlantic. Oh man, I needed this! Bright and energetic, exuberant even, it perks up the mood and goes down fast. 13%. Certified B Corp. Ingredient and nutrition labeling, and in a modest way that doesn’t occupy a lot of label space. (Since it’s not required, presumably there are no minimum font size requirements.) More wineries should follow this example. Dave McIntyre's WineLine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Thanks for reading Dave McIntyre's WineLine! This post is public so feel free to share it. Share 1 Some restraint may be required. 2 Especially the bubblies.
Can pesticide exposure before pregnancy affect babies’ health?
A study co-authored by UCLA researchers suggests certain chemical compounds correlated with lower newborn health scores.
iPhone Air Said to Be Roughly Twice as Popular as iPhone 16 Plus
While it certainly has its critics, the iPhone Air appears to have validated Apple's decision to retire the iPhone Plus, if new results from an independent analysis are anything to go by. Crowdsourced Speedtest data published by Ookla suggests the iPhone Air captured 6.8 percent of iPhone 17 generation samples in the U.S. during the fourth quarter of 2025, up from the 2.9 percent share the iPhone 16 Plus managed in the same launch window a year earlier.
Longhorns secure major upgrade following NCAA decision on eligibility waiver
Improving the offensive line has been a major focus for Texas this offseason, and the Longhorns got a big piece of that puzzle locked in on Wednesday following weeks of eligibility uncertainty.
Bursaries open for help with sports memberships
Children meeting certain criteria can get up to £200 from Epsom & Ewell Borough Council.
Immigration crackdown impact on local Latino-owned businesses
Latino business owners told WRAL News that fear and uncertainty following a nationwide crackdown in immigration enforcement are keeping some families out of public spaces, leaving small businesses struggling to survive. This story was written by Oriana Torre, a senior graduating journalism student at the University of Florida, participating in the CBC-UNC News Media Multiplatform Fellowship.
‘The Comeback’ took on Hollywood long before ‘The Studio.’ Now, Valerie Cherish will have her curtain call
“The Comeback” was by no means the first series to hold a funhouse mirror up to the entertainment industry, but the comedy starring co-creator Lisa Kudrow, which returns for its final season on Sunday, has certainly always done it in its own navel-gazing yet endearing way.
Friction without contact discovered as magnetic forces break a 300-year-old law
Researchers have uncovered friction without contact—driven entirely by magnetic interactions. As two magnetic layers slide, their internal forces compete, causing constant rearrangements that dramatically increase resistance at certain distances. This creates a surprising peak in friction instead of a steady rise, breaking a long-standing physics law.
The end of the ISS is looming, and the US could have a big problem
As the US sets its sights on establishing a permanent base on the moon, its foothold in an area of space much closer to home is growing more uncertain.
Why the Trump administration is easing sanctions on certain Iranian oil stockpiles
Trump administration officials are making a desperate push to secure every available barrel of oil amid a worsening energy crisis — even if it means lifting sanctions on the very country that they’re fighting against.
Why Tencent Music Entertainment Plunged Almost 30% This Week
The Chinese music streaming leader posted decelerating subscription revenue and said it would no longer disclose certain metrics going forward.
Judge rules US government overreached with transgender health care declaration
A federal judge has ruled that the government overreached when it declared certain types of gender-affirming care unsafe for young people.
Maternal and Infant Health in State Rural Health Transformation Proposals Set Promising Priorities in an Uncertain Landscape
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A Grip on Sports: The Zags survive a first-round rock fight in Portland, one that also caused contusions for those watching from home
A GRIP ON SPORTS • There was one thing I was certain of when I began writing this column almost 15 years ago. The day Chuck Norris died, I would share my story of the lone interaction I had with the “Walker, Texas Ranger” star. It has everything. High school football. A rickety press box. Family. Sports writing. But, alas, it may have to wait. Today is just not the day.
Judge rules US government overreached with transgender health care declaration
A federal judge has ruled that the government overreached when it declared certain types of gender-affirming care unsafe for young people
Judge rules the government overreached with transgender health care declaration
A federal judge has ruled that the government overreached when it declared certain types of gender-affirming care unsafe for young people.
Steelers await Aaron Rodgers decision as NFL draft nears
Ben Roethlisberger weighs in as uncertainty surrounds Pittsburgh’s QB plan, with new weapons adding pressure for clarity before the 2026 NFL Draft.
Maggie Haberman: Trump ‘showing a greater tolerance for certain political pain’ related to the Iran war
De'Anthony Melton shares honest reply about uncertainty of his Warriors future
De'Anthony Melton discussed the uncertainty of his future with the Golden State Warriors as he is expected to enter unrestricted NBA free agency.
Treasury Secretary Bessent unveils plan to flood market with oil amid Iran war
Treasury Secretary Scott Bessent joins ‘Mornings with Maria’ to discuss the Iran war, surging oil prices, market volatility, Fed uncertainty, Powell’s future and the U.S. strategy to stabilize the global economy.
Eveleth: Congress must fix joint employer rules for Michigan businesses
Former Owosso mayor Chris Eveleth explains how 'joint employer' rules create uncertainty for Michigan small businesses.
Federal Reserve holds interest rates steady
Federal Reserve policymakers chose to leave interest rates unchanged at their March meeting amid a softening labor market and uncertainty over the economic impact of the Iran war.
Trump nominee Mullin expected to get quick confirmation to replace Noem at DHS
Republicans almost certain to push through appointment following the ousting of Noem amid public backlash to her aggressive immigration approach
Illinois businesses shift into growth mode after strong 2025
Local companies are confident after surviving years of high interest rates, inflationary pressure and tariff uncertainty, says a new BMO outlook.
Tiger Woods provides health update as he eyes return at The Masters
We are three weeks away from The Masters, and we still aren’t certain if the greatest golfer of all time will be teeing it up at Augusta National. Tiger Woods underwent his seventh back surgery towards the end of 2025, and did not lay out a timeline for his return.
Port of Charleston's box-ship business hits a nearly 6-year low
The operator of the Port of Charleston says it isn't insulated from the "chaos" and "uncertainty" that's been roiling the shipping industry. Controlling costs will be key, the agency's CEO says.
Juliana Stratton wins Democratic primary, set to become Illinois’ second Black woman senator
Lt. Gov. Juliana Stratton is all but certain to make history, becoming one of three Black women to serve in the Senate at the same time.
Let the games begin: Foxboro signs off on entertainment license for FIFA
The 2026 FIFA World Cup is officially coming to Gillette Stadium this summer after months of uncertainty.
Machine learning analysis of CT scans
An AI-powered tool can interpret 3D images from CT scans and diagnose certain disorders.
Blatnik Bridge funding uncertainty rattles Twin Ports business plans
With the $1.8 billion replacement project in limbo, regional leaders say delays could raise costs and complicate years of planning for a five-year construction closure.
Devils Rally Past Bruins in OT
It’s nights like these that make you wonder, what could have been. The New Jersey Devils certainly didn’t look like the hapless, directionless mess of a hockey team that spent the past three-plus months struggling to get out of its own way while plummeting to the darkest depths of the Eastern Conference standings. Well, maybe […]
A strange twist in the universe’s oldest light may be bigger than we thought
Scientists studying a mysterious effect called cosmic birefringence—a subtle twist in the polarization of the universe’s oldest light—have developed a new way to reduce uncertainty in how it’s measured. This faint rotation in the cosmic microwave background could point to entirely new physics, including hidden particles such as axions and clues about dark matter or dark energy.
UK mortgage shelf-life nosedives amid market uncertainty; oil rising again
Rolling coverage of the latest economic and financial news
Who slept best last night: Stefano Domenicali
Formula 1 delivered in Shanghai. There are still issues to address, but the new F1 certainly isn't broken
Bob on Business: UTA business professor sees uncertainty ahead for financial markets, mortgage rates
Also, energy assets sold and Compass expands at Clearfork.
Texas Could See A Spike In Raids On Hemp Businesses Under New Rules, Industry Advocates Fear
“People don’t know what the rules are. They don’t know what is in effect at a certain time… There is overall confusion around regulations, and that is the biggest issue.” By Stephen Simpson, The Texas Tribune Dallas attorney Chelsie Spencer specializes in making sure Texas businesses that sell hemp-derived THC products know how to stay […]
Why Brenna Huckaby’s Paralympics future is uncertain after bronze medal
USA Para snowboarder Brenna Huckaby faces uncertainty around her classification in the Paralympics. Here's why.
NHS and MoD will be urged to buy British tech to drive growth amid Iran crisis
Treasury minister Spencer Livermore trails new strategy as chancellor pins hopes on benefits of AI amid global uncertainty
Drop Zone entertainment complex with golf bays, pickleball courts to open April 1
Kearney residents who have long driven to Lincoln or Omaha for certain entertainment options will soon have a new local alternative.Drop Zone, a new entertainme
Manufacturers’ Q1 Survey: Trade Business Challenges Persist, but Optimism Up
Washington, D.C. – As the review of the United States–Mexico–Canada Agreement gets underway, a majority of manufacturers report they utilize either Canada or Mexico for critical parts of their supply chains—at a time when trade uncertainty remains manufacturers’ top business concern, according to the National Association of Manufacturers Q1 2026 Manufacturers’ Outlook Survey. The survey […]
Eating These 2 Surprising Fruits Every Day May Help Support Heart Health
New research found that eating mango and avocado daily may benefit certain heart health markers.
Congressman Neal, BHS Talk Local Health Care in 2026
Congressman Neal says access to health care is also important as an economic factor in the area. PITTSFIELD, Mass. — In a time of federal funding uncertainties,...
WhatsApp launches preteen accounts, here’s how they work
WhatsApp has announced that preteens can now use its messaging platform via new parent-managed accounts that come with certain restrictions.
Tariff uncertainty continues to loom over local small business
HPR speaks with local small business owner David Pang to discuss the effects of President Trump's tariffs and the recent Supreme Court ruling.
Iran crisis: Three ways this could end
From one moment to the next, this Iran crisis appears to be cascading in ways that are increasingly uncertain for governments, investors and ordinary citizens alike. Much now turns on the individual decisions of unpredictable leaders, including President Donald Trump, and now perhaps Iran’s new and untested supreme leader, Mojtaba Khamenei.
Why authentic leadership matters more than ever
Mission-driven leaders are facing unprecedented pressure as economic uncertainty, political polarization, rapid technological change and growing public scrutiny reshape how organizations operate, Harvard Business Review writes. A recent analysis highlights how these overlapping forces are turning routine decisions into tests of values, strategy and credibility. Research based on surveys and discussions with nonprofit and social […]
Nichols’ Notes: Devils Blueline Uncertainty; Explosive Summer Shake-Up?
Mass. business confidence turns positive for the first time in a year
The index climbed into an optimistic range as AI and earnings gains took hold, but before uncertainty tied to the Middle East conflict began.
NEW NFIB SURVEY: Small Businesses Report Higher Sales and Less Uncertainty
NFIB's Small Business Optimism Index fell 0.5 points in February to 98.8 but remained slightly above the 52-year average of 98.
The New Brand Playbook for Unpredictable Times
Multi-brand upheaval and geopolitical uncertainty are impacting business in 2026. Here’s how independent labels are buckling down accordingly.
Clermont’s plan to protect local businesses as Winter Garden loses them
Winter Garden's future is uncertain as several downtown buildings are being sold. Neighboring Clermont has a mission to stay local.
Former Obama adviser warns of uncertain path in Iran during annual Samuel C. Waters Lecture in Political Science at Presbyterian College
With tensions escalating in the Middle East following recent U.S. attacks on Iran, former White House deputy national security adviser Ben Rhodes told a Presbyterian College audience that the long-term […]
Trump’s ‘roaring economy' meets a rough start to 2026 with job losses, rising gas prices and uncertainty
Donald Trump promised that 2026 would be a bumper year for economic growth. Instead it's kicked off with job losses, rising gasoline prices and more uncertainty about America’s future.
Sony is testing dynamic pricing on the PlayStation Store
Users in certain regions are being offered personalised discounts of up to 17%
These 3 Valley Junction businesses are expanding
Despite tariffs and economic uncertainties facing Valley Junction business owners, several shops are expanding.
Fee on health insurers to fund abortion services debated in WA Legislature
Certain insurers in Washington state could soon need to foot the bill for additional abortion grant funding.
Britain’s job market ‘floundering’ as companies remain cautious about hiring
Data shows labour market is still in a fragile position due to economic uncertainty, with few signs of recovery
'LOTR' star Elijah Wood doesn't want anybody else to play Frodo as long as he's 'alive and able'
Elijah Wood won't confirm whether or not he will appear in 'The Lord of the Rings: The Hunt for Gollum,' but he has made it clear that he won't let go of his beloved hobbit without a fight: 'I certainly wouldn’t want anybody else to play Frodo.'
Samsung Galaxy S26 Ultra shows camera improvements compared to S25 Ultra, can't catch up to Apple iPhone 17 Pro
On paper, the Samsung Galaxy S26 Ultra has only received a few camera upgrades. An initial comparison by DxOMark now shows that Samsung was able to drastically improve the image quality in certain scenarios, but the camera system of the Galaxy S26 Ultra is not completely free of problems.
The FBI Warns Americans To Replace These Wi-Fi Routers
According to the FBI, if you have certain older Wi-Fi routers from Linksys or Cisco, consider replacing them to avoid known vulnerabilities to malware.
Balkans on edge: Kosovo political crisis sparks fears of renewed instability
Trump ally Kosovo President Osmani calls snap elections after parliamentary deadlock blocks presidential vote, creating political uncertainty in the Balkans.
Scientists say this simple diet change could transform your gut health
A growing trend called “fibermaxxing” is putting dietary fiber in the spotlight—and for good reason. Fiber plays a powerful role in keeping the body healthy, from supporting digestion and feeding beneficial gut microbes to helping regulate blood sugar and cholesterol. Researchers say getting enough fiber may even lower the risk of conditions like obesity, diabetes, and certain cancers.
Scientists say this simple diet change could transform your gut health
A growing trend called “fibermaxxing” is putting dietary fiber in the spotlight—and for good reason. Fiber plays a powerful role in keeping the body healthy, from supporting digestion and feeding beneficial gut microbes to helping regulate blood sugar and cholesterol. Researchers say getting enough fiber may even lower the risk of conditions like obesity, diabetes, and certain cancers.
What Live Nation Entertainment (LYV)'s Antitrust Trial Over Ticketmaster Dominance Means For Shareholders
The U.S. Department of Justice and 30 states have taken Live Nation Entertainment and Ticketmaster to a jury trial in New York, alleging that they abused their dominance in live music ticketing, promotions, and venue contracts to harm fans, artists, and competitors. Because the case raises the possibility of forced divestiture of Ticketmaster or sweeping changes to venue contracts, it poses material uncertainty for Live Nation’s business model and future industry structure. We’ll now examine...
Broncos 'biggest need' revolves around Alex Singleton, Dre Greenlaw uncertainty
This is a sneaky big need for the Broncos this offseason.
Big Tech’s Uncertain Future in the Persian Gulf
The expanding war in the Middle East has added new risks to the trillions of dollars in investments that tech companies have planned in the region.
Indianapolis business owners faced with rising prices amid economic uncertainty
Valve’s Steam Machine becomes less of a certainty in 2026 after passing product update
Valve got tons of folks excited about its new Steam Machine, catering to gamers who want a familiar library and...
Apple on MacBook Neo Design: 'We're Certainly Not Making Any Compromises'
While the MacBook Neo starts at just $599, or an even lower $499 for college students, Apple has insisted that it did not make any design compromises. "It's undeniably a MacBook, we're certainly not making any compromises on the design and that's really important," said Apple's vice president of industrial design Molly Anderson, in an interview with architecture and design publication Dezeen.
Bringing advanced neurological care to South Texas families - UT Health San Antonio
“We’re not only treating conditions — we’re caring for people across the full spectrum of brain health. When someone hears the words, “You have ALS,” or “This may be dementia,” life changes instantly. Questions come faster than answers, appointments multiply and the future feels uncertain. For patients and families navigating that uncertainty, UT Health San […]
Carbon emissions now more than double the planetary boundary, analysis finds
Earth is not infinite. Pollution beyond certain levels threatens the climate and ecosystems. To prevent this, scientists have proposed planetary boundaries, defining the safe operating limits of the Earth ...
Public health needs steady budgets – and federal funding uncertainty cause real harms, even if the money is later restored
Public health depends on long-term planning, and when that planning is interrupted, some programs never recover.
GLP-1 Drugs May Raise the Risk of Osteoporosis and Gout, Study Suggests
New research suggests that prolonged GLP-1 use may increase the risk of certain bone and joint conditions.
LSU sports is barely in the black financially, with uncertain financial times ahead
As LSU sports barely breaks even financially, difficult times potentially lie ahead for both its athletic teams and academic programs.
What to expect in today’s jobs report
Economic uncertainty tied to President Donald Trump’s signature trade policies has led many small businesses to lay off workers, delay expansion plans or scale back production.
Health screening in Sterling Heights helps early detection of cancer in firefighters
Firefighters face invisible risks long after the flames are out, including elevated rates of certain cancers. Now there are efforts to help detect them early to help save those who save others on a daily basis.
Business Summit to Focus on Uncertainty in a Global Economy
Business and government leaders will speak about managing economic uncertainties at the Summit on March 27.
Iran war looms large over Berlin's global tourism fair
Closed airspace, stranded cruise ships, uncertainty for hundreds of thousands of travellers: The war in the Gulf is a shock to the tourism industry. Travel warnings are in place for around a dozen countries in the region.
What to expect in Friday’s jobs report
Economic uncertainty tied to President Donald Trump’s signature trade policies has led many small businesses to lay off workers, delay expansion plans or scale back production.
Restaurant in 29 Palms says war in Iran has impacted its business
TWENTYNINE PALMS, Calif. (KESQ) – As the potential for an American ground invasion of Iran remains in question, uncertainty looms in the High Desert. The City of Twentynine Palms is closely intertwined with their Marine neighbors to the north, just five miles away from downtown. Among the people who live and work in the area,
Breaking Down BYU’s Defense During Spring Ball
BYU football is in Spring Ball mode now. Last week, we addressed the offensive outlook. Now we take a look at one of the best units in the entire Big 12 last year, the BYU defense. Jay Hill is gone to Michigan after spending the last three seasons as BYU’s defensive coordinator. He certainly left […]
Buchanan Street residents split over business restrictions from zoning
Buchanan Street neighbors and business owners are weighing the pros and cons of applying a new zoning tool that limits certain types of businesses.
Small business owners: tell us how Trump’s tariff war has affected you
Trump’s sweeping tariffs have left many businesses facing higher costs and uncertainty. We want to hear how smaller companies are navigating the fallout
Michigan Medicine resists significant cuts by Blue Cross Blue Shield of Michigan that would limit patient access
Michigan Medicine is informing patients about potential impacts that could result in changes for those insured by certain Blue Cross Blue Shield of Michigan commercial health plans if an agreement is not reached by June 30, 2026.
The global fallout of RFK Jr's vaccine policies
In his role as Secretary of Health and Human Services, Robert F. Kennedy, Jr. is changing how the United States approaches vaccines. But those changes aren’t limited to the United States. NPR global health correspondent Gabrielle Emanuel joins Short Wave to talk about two examples of how the global public health landscape may be shifting. First, the United States’ ultimatum to an international vaccine group. Second, the uncertain fate of a vaccine trial. Some researchers are calling the trial a “unique” opportunity, and others are calling it “unethical.” Read more of global health correspondent Gabrielle Emanuel’s work here.Interested in more global health? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.