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Sports Daily: Shockers ready for NIT Round 3

We get you ready for Shocker basketball tonight, now just a way from the NIT semifinals.

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Mar 24 • 8:00 AM EDT • Sports • kwch.com
Salamander Migration Has New Citizen Science Component

Each spring, blue-spotted salamanders emerge from their underground burrows at Presque Isle Park in Marquette and venture across the road to lay their eggs. Northern Michigan University students have been involved in conservation, data collection and public education efforts for this annual event, but this year, the general public is invited to play a more active role in salamander migration research. Northern Michigan University Biology Department Head Jill Leonard encourages community members to participate in the Marquette Citizen Science Project.

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Mar 24 • 8:00 AM EDT • Science • news.nmu.edu
Health Care Roundup: Market Talk

Find insight on Novo Nordisk, Novartis, Top Glove and more in the latest Market Talks covering Health Care.

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Mar 24 • 7:35 AM EDT • Health • wsj.com
New York Yankees Reveal Cryptic, Concerning Update on Top Prospect
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Mar 24 • 7:00 AM EDT • Sports • sports.yahoo.com
Public Health Alert For Ground Beef—‘Do Not Consume’

The U.S. Department of Agriculture’s Food Safety and Inspection Service issued a public health alert for certain ground beef products.

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Mar 24 • 6:44 AM EDT • Health • newsweek.com
Women's NCAA Tournament Round 2 winners, losers: Virginia make history, Iowa fizzles

USA TODAY has followed every upset, buzzer-beater and game from the 2026 Women's NCAA Tournament and rounded up our winners and losers from round two:

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Mar 24 • 5:12 AM EDT • Sports • usatoday.com
How COVID turned America against science — and what it will take to win it back

Tony Fauci was not just jerking the country around.

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Mar 24 • 5:00 AM EDT • Science • yahoo.com
How COVID turned America against science — and what it will take to win it back

Tony Fauci was not just jerking the country around.

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Mar 24 • 5:00 AM EDT • Science • fortune.com
Special Battleground Report on Food and Health Part II: Messages

This Navigator Research report covers messaging guidance to effectively communicate on food and health-related issues to Americans in the battleground.

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Mar 24 • 4:45 AM EDT • Health • navigatorresearch.org
Who experts predict 49ers will select with first-round pick in 2026 NFL Draft

Here's who writers and experts around the country believe the San Francisco 49ers will select in the first round of the 2026 NFL Draft.

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Mar 23 • 10:47 PM EDT • Sports • nbcsportsbayarea.com
Dodgers' Dave Roberts Gives Timeline on Tommy Edman, Blake Snell

Dodgers manager Dave Roberts gave a brief timeline for the return of Tommy Edman and Blake Snell.

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Mar 23 • 8:46 PM EDT • Sports • sports.yahoo.com
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Pokémon Champions Releases on Nintendo Switch and Nintendo Switch 2 on April 8, 2026

Take on Trainers from around the world and battle with recently discovered Mega-Evolved Pokémon.

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Mar 23 • 8:00 PM EDT • Technology • pokemon.com
Insulin pills may soon replace daily injections

For over a century, scientists have chased the dream of insulin pills, but the digestive system kept destroying the drug before it could work—forcing millions of patients to rely on daily injections. Now, researchers at Kumamoto University have developed a clever workaround using a tiny peptide that helps insulin slip through the intestinal wall.

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Mar 23 • 8:00 PM EDT • Science • sciencedaily.com
Voice of America journalists allege Trump is making news outlet a propaganda source

Some journalists at Voice of America charged in a lawsuit Monday that the Trump administration — while largely shutting down the government-run outlet that provides news around the world — has turned what remains into a voice for propaganda.

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Mar 23 • 7:22 PM EDT • Politics • pbs.org
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Trump places replica Christopher Columbus statue near the White House

A statue of Christopher Columbus has been placed on the grounds of the Eisenhower Executive Office Building adjacent to the White House, the latest effort by President Donald Trump's administration to recognize the controversial explorer.

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Mar 23 • 6:34 PM EDT • Politics • pbs.org
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SP40 Restomod Is Built Around The One Ford That Edsel Actually Got Right

Carbon-bodied SP40 brings the style of Edsel Ford’s one-off speedster to a wider audience

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Mar 23 • 5:22 PM EDT • Technology • carscoops.com
Scientists Connect “Time Crystals” to the Outside World in Groundbreaking Experiment

A newly demonstrated link between a time crystal and a mechanical system opens a door scientists once thought closed.

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Mar 23 • 4:46 PM EDT • Science • scitechdaily.com
2026 NCAA Tournament second round schedule: March Madness bracket, game dates, tip times, TV channels

Check out the master schedule for the first and second rounds of the 2026 NCAA Tournament so you can watch all the March Madness

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Mar 23 • 2:50 PM EDT • Sports • cbssports.com
Mexico's Karim Lopez reportedly declares for the 2026 NBA Draft

Lopez could become the first player of Mexican descent selected in the first round.

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Mar 23 • 2:24 PM EDT • Sports • sports.yahoo.com
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No health insurance? Here are other ways to access affordable health care in Alaska

Around 25,000 Alaskans are facing skyrocketing insurance costs in 2026. So we found some other options for accessing affordable care.

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Mar 23 • 2:13 PM EDT • Health • alaskapublic.org
Uplifting and Not Ceding Ground on Health Equity Practice Is Critical to Strengthening Public Health and the Health of the Nation

Public health science gains in the last quarter century in the United States have been formidable due to a focus on structural and social determinants of health, thereby enhancing understanding of the role of inequitable policies in shaping health inequities and inequitable access to ameliorative resources.

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Mar 23 • 1:54 PM EDT • Health • milbank.org
Senior Playgrounds Are the Latest Healthy Aging Trend With Real Benefits

They're full of low-impact equipment for seniors to get their bodies moving and keep their minds active.

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Mar 23 • 1:49 PM EDT • Health • today.com
Uncommon Ground seeks new operator as longtime Wrigleyville restaurateurs plan to retire

The longtime restaurateurs behind Uncommon Ground at 3800 N. Clark St. in Wrigleyville are seeking a new operator for the restaurant, brewery and music venue.

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Mar 23 • 1:45 PM EDT • Business • chicagobusiness.com
Brian Doherty, 57, Dies; Chronicled Libertarians and Other Outsiders

Fascinated by the fringes, he wrote a definitive history of libertarianism and books about underground comics and the Burning Man festival.

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Mar 23 • 1:35 PM EDT • Politics • nytimes.com
WATCH LIVE: Trump joins Memphis Safe Task Force roundtable, initiative aimed at combating crime
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Mar 23 • 1:00 PM EDT • Politics • pbs.org
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Health Care Roundup: Market Talk

Find insight on Novartis, Sandoz Group and more in the latest Market Talks covering Health Care.

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Mar 23 • 12:27 PM EDT • Health • wsj.com
Antarctica could warm 1.4 times faster than the rest of the Southern Hemisphere in the coming decades, study finds

Antarctica could warm much faster than its surroundings over the next few decades due to a phenomenon known as polar amplification that is well established in the Arctic.

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Mar 23 • 12:13 PM EDT • Science • livescience.com
2026 Eagles mock draft roundup 5.0: Just a month away

We’re just a month away from the start of the 2026 NFL Draft. Here are some options for the Eagles.

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Mar 23 • 10:59 AM EDT • Sports • nbcsportsphiladelphia.com
Apple Reportedly Preparing 'Biggest Set of iPhone Revamps' Ever

Apple is working on "the biggest set of iPhone revamps in the product's history," according to the latest word from Bloomberg's Mark Gurman. Specifically, he is referring to the long-rumored foldable iPhone, as well as an ambitious 20th-anniversary iPhone with a truly "edge-to-edge" design.

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Mar 23 • 9:28 AM EDT • Technology • macrumors.com
What’s the new 'Background Security' on the iPhone? What we know.

Apple's new Background Security Improvements operate between software updates, providing "lightweight security releases."

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Mar 23 • 9:11 AM EDT • Technology • usatoday.com
Cowboys mock draft tracker: A trade might make sense early

How interested are you in trading back in the first round?

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Mar 23 • 9:00 AM EDT • Sports • sports.yahoo.com
Happening this week | Women Working and Winning in Politics Roundtable

The 3rd annual Women Working & Winning in Politics Roundtable will be held at Dillard University

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Mar 23 • 8:20 AM EDT • Politics • wwltv.com
Live Science Today: Earth hits record energy imbalance, Hawaii floods and NASA prepares for Artemis II launch

Monday, March 23, 2026: Your daily roundup of the biggest science stories making headlines.

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Mar 23 • 8:05 AM EDT • Science • livescience.com
Illinois, the youngest team in Women's NCAA tournament, proving age is just a number

No. 7 seed Illinois faces No. 2 seed Vanderbilt in Nashville in the second round of the Women's NCAA Tournament.

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Mar 23 • 7:03 AM EDT • Sports • usatoday.com
UCLA tries to enjoy rare opportunity for Lauren and Sienna Betts

UCLA works to celebrate Lauren and Sienna Betts as successful sisters and individual playmakers pushing to help the Bruins win.

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Mar 23 • 6:30 AM EDT • Sports • latimes.com
2026 NFL mock draft: Surprises in top 10 of latest first-round projection

The 2026 NFL Draft is just a month away, and our latest mock draft features a few surprises materializing in the top 10 picks.

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Mar 23 • 6:05 AM EDT • Sports • usatoday.com
Microsoft Plans Better Windows 11 RAM Management and a Smoother User Experience

Microsoft recently announced a plethora of changes coming to Windows 11 to reshape the operating system into a completely stable and enjoyable experience. Today we learn that Microsoft plans a major background usage overhaul with future updates, focusing on RAM usage and overall memory management, s...

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Mar 23 • 5:49 AM EDT • Technology • techpowerup.com
Ohio State vs Notre Dame predictions, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 3 Ohio State vs No. 6 Notre Dame in the 2026 women's NCAA Tournament on March 23

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Mar 23 • 5:08 AM EDT • Sports • usatoday.com
UConn vs Syracuse predictions, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 1 UConn vs No. 9 Syracuse in the 2026 women's NCAA Tournament on March 23

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Mar 23 • 5:08 AM EDT • Sports • usatoday.com
Where to watch South Carolina vs. USC in March Madness Second Round: Time, TV Channel

The No. 1 South Carolina Gamecocks face the 9 USC Trojans in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 23 • 5:08 AM EDT • Sports • usatoday.com
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Energy Attacks in War on Iran Could Turn Economic Shock Into Long-Term Damage

A new phase targeting oil and gas infrastructure in the Persian Gulf threatens to hurt businesses and customers around the world for months or even years.

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Mar 23 • 5:02 AM EDT • Business • nytimes.com
Sheffield business owners 'don't feel safe' next to illegal waste site

An Attercliffe dumping ground is identified as one of the worst in the country by the government.

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Mar 23 • 4:13 AM EDT • Business • bbc.com
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TCU completes comeback, avoids Washington's NCAA Tournament upset bid

TCU women's basketball’s 62-59 overtime win over Washington in the second round of March Madness wasn’t pretty, but it was resilient.

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Mar 23 • 2:04 AM EDT • Sports • usatoday.com
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I tested ChatGPT vs. Perplexity with the same 5 prompts — the winner surprised me

AI Madness Round 1: The Heavyweight meets the Challenger in our first round of Tom's Guide AI Madness

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Mar 23 • 2:00 AM EDT • Technology • tomsguide.com
Chris Sale 2026 MLB Season Preview
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Mar 22 • 11:56 PM EDT • Sports • sports.yahoo.com
State lawmakers debate new round of business tax cuts

Rep. Joe Sweeney, R-Salem, and Sen. Donovan Fenton, D-Keene, discussed their support and opposition to House Bill 155, which would reduce the business enterprise tax from 0.55% to 0.50%.

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Mar 22 • 11:27 PM EDT • Business • wmur.com
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Kansas squanders its best player as Darryn Peterson's college career with second-round loss to St. John's

The Peterson era in Lawrence is likely over.

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Mar 22 • 9:54 PM EDT • Sports • cbssports.com
Florida basketball stunned by Iowa in March Madness Round 2 upset

Florida basketball was stunned by Iowa, ending its hopes to repeat as national champions in the Men's NCAA Tourrnament.

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Mar 22 • 9:34 PM EDT • Sports • usatoday.com
Statue of Christopher Columbus installed on White House grounds

A statue of Christopher Columbus has been erected outside of an ornate federal office building on the White House grounds — the latest sign of the Trump administration’s efforts to reshape cultural and historical representations across the nation’s capital.

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Mar 22 • 9:09 PM EDT • Politics • cnn.com
Kansas coach Bill Self unsure about future after buzzer-beater loss to St. John's: 'I haven't decided'

After a heartbreaking last-second loss in the second round of the NCAA tournament, Self wasn't ready to discuss his coaching future.

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Mar 22 • 8:39 PM EDT • Sports • sports.yahoo.com
Alabama vs. Texas Tech odds, time, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Texas Tech vs. Alabama picks for the NCAA Tournament 2026 second-round game on Sunday

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Mar 22 • 8:03 PM EDT • Sports • cbssports.com
Alcaraz eyes clay court season after early Miami exit

World number one Carlos Alcaraz remained confident his game is improving despite a third-round exit at the Miami Open, and after a few days to reset he'll be turning his attention to the clay court season.My mind right now is to take some days off, to reset my mind, reset the batteries, be ready and in good shape for the clay season."

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Mar 22 • 7:44 PM EDT • Sports • sports.yahoo.com
This Couple Turned A Facebook Marketplace Side Hustle Into A Seven-Figure Business

When Harrison Gordon and Paige Sandher couldn't find a modular custom sofa that was also affordable, they designed their own. They built a fast-growing business around their idea.

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Mar 22 • 6:19 PM EDT • Business • forbes.com
Arizona vs Utah State live updates: Prediction, how to watch March Madness Round 2 game

Folks were gushing about Jerrod Calhoun and Utah State's offense in Round 1. Arizona is a whole different obstacle. Follow March Madness Round 2 game.

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Mar 22 • 4:05 PM EDT • Sports • usatoday.com
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Full 7-round Arizona Cardinals mock draft simulation

We have a new 7-round mock draft for the Arizona Cardinals.

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Mar 22 • 3:51 PM EDT • Sports • sports.yahoo.com
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Florida vs Iowa live updates: Prediction, how to watch March Madness Round 2 game

Defending national champion Florida didn't need a warm-up to get going in their NCAA title defense. Will Iowa provide any resistance in March Madness?

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Mar 22 • 2:23 PM EDT • Sports • usatoday.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Kentucky vs. Iowa State odds, time, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Kentucky vs. Iowa State picks for the NCAA Tournament 2026 second-round game on Sunday

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Mar 22 • 1:03 PM EDT • Sports • cbssports.com
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Business briefs: PNW honors doles out honors on Founders Day

News and events around the area

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Mar 22 • 1:00 PM EDT • Business • chicagotribune.com
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2026 NCAA Men's Basketball Tournament Highlights: Round of 32 Continues

The 2026 NCAA Men’s Basketball Tournament continues with the Round of 32 on Sunday, and we've got you covered with all the highlights!

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Mar 22 • 12:03 PM EDT • Sports • foxsports.com
Chiefs’ 2026 NFL Mock Draft roundup after NFL Free Agency

A closer look at the Chiefs’ 2026 mock draft outlook after free agency, with linked to edge help, cornerback, and offensive line support.

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Mar 22 • 11:42 AM EDT • Sports • sports.yahoo.com
Purdue vs Miami live updates: Prediction, how to watch March Madness Round 2 game

Braden Smith has the NCAA assists record, now he can focus on his main goal: a championship. Miami stands in Purdue's way in Round 2 of March Madness.

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Mar 22 • 9:44 AM EDT • Sports • usatoday.com
Raptors, Suns playing for postseason in season's final stretch

Two of the best turnaround stories in the NBA this season belong to the Toronto Raptors and the Phoenix Suns, who each missed the playoffs a year ago.

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Mar 22 • 8:52 AM EDT • Sports • cbssports.com
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NFL Network: What's next for Bills QB Josh Allen? (video)

NFL Network roundtable looks ahead to Josh Allen and the Bills in 2026.

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Mar 22 • 8:45 AM EDT • Sports • sports.yahoo.com
Why mosquitoes always find you and how they decide to attack

Scientists have finally cracked how mosquitoes decide where to fly—and it’s not by following each other. Instead, each insect independently reacts to visual cues and carbon dioxide, zeroing in on humans when both signals align. Dark colors and CO2 together create the strongest attraction, triggering swarming and biting behavior. This insight could reshape how we design traps and prevent mosquito-borne diseases.

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Mar 22 • 8:00 AM EDT • Science • sciencedaily.com
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Duke vs Baylor predictions, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 3 Duke vs No. 6 Baylor in the 2026 women's NCAA Tournament on March 22

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Mar 22 • 5:08 AM EDT • Sports • usatoday.com
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Where to watch Minnesota vs. Ole Miss in March Madness Second Round: Time, TV Channel

The No. 4 Minnesota Golden Gophers face the 5 Ole Miss Rebels in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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Where to watch Duke vs. Baylor in March Madness Second Round: Time, TV Channel

The No. 3 Duke Blue Devils face the 6 Baylor Bears in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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Where to watch Oklahoma vs. Michigan State in March Madness Second Round: Time, TV Channel

The No. 4 Oklahoma Sooners face the 5 Michigan State Spartans in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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What time is Michigan women's basketball's second round game?

Michigan cruised to a blowout victory over Holy Cross in their opening NCAA Women's Tournament matchup. See who they play next.

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Mar 22 • 4:46 AM EDT • Sports • sports.yahoo.com
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David Suzuki at 90: A life in science, and a warning still unheard

With ninety laps around the sun, David Suzuki reflects on a lifetime of science advocacy and environmental work. Despite decades of effort, he warns that humanity may have already crossed a tipping point on climate change.

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Mar 22 • 4:00 AM EDT • Science • cbc.ca
'Heartbreaking' - fighter pay debate laid bare at UFC London

The debate around fighter pay reemerges at UFC London amid some career-defining performances on the undercard.

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Mar 22 • 2:39 AM EDT • Sports • sports.yahoo.com
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2025-26 Women's Second Round Odds: Spreads, Lines for all 16 Games

Check out the odds for all 16 games of the women's NCAA Tournament Round of 32.

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Mar 22 • 1:52 AM EDT • Sports • foxsports.com
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France Is Voting for Thousands of New Mayors. Here’s Why It Matters.

The far-right party had first-round successes in several cities, but so did the far left. Sunday’s second round may clarify who has real momentum.

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Mar 22 • 12:01 AM EDT • Politics • nytimes.com
Another Illinois basketball player enters legendary status in NCAA tournament

The Illinois basketball team has had some incredible performances this season, and one player just put up an amazing Round of 32 showing against VCU.

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Mar 21 • 11:08 PM EDT • Sports • sports.yahoo.com
Tottenham Hotspur have chance to turn relegation narrative around against Nottingham Forest

Both sides are barely hovering above the relegation zone, Spurs boasting one point over 18th-place West Ham while Nottingham are only above the drop zone on goal differential

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Mar 21 • 10:34 PM EDT • Sports • cbssports.com
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Coaches in elite company clash when Kansas faces St. John's

SAN DIEGO -- Only three active head coaches in Division I college basketball have won multiple national championships. Two of them meet for a berth in the Sweet 16 when Bill Self's No. 4 Kansas Jayhawks face Rick Pitino's No. 5 St. John's Red Storm on Sunday in the second round of the NCAA Tournament East Region.

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Mar 21 • 9:01 PM EDT • Sports • cbssports.com
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Amanda Peet Shares Breast Cancer Diagnosis

Amanda Peet detailed her recent breast cancer diagnosis in a new essay, sharing that her health battle coincided with both of her parents' final months in hospice care.

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Mar 21 • 8:27 PM EDT • Health • eonline.com
Webb Telescope spots “impossible” atmosphere on ancient super Earth

Astronomers have uncovered surprising evidence of a thick atmosphere surrounding TOI-561 b, a scorching, fast-orbiting rocky planet once thought too extreme to hold onto any gas. Using NASA’s James Webb Space Telescope, researchers found the planet is far cooler than expected for a bare rock, hinting at a heat-distributing atmosphere above a churning magma ocean. This strange world—where a year lasts just over 10 hours and one side is locked in eternal daylight—may even be rich in volatile materials, behaving like a “wet lava ball.”

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Mar 21 • 8:00 PM EDT • Science • sciencedaily.com
More school-based health clinics fill growing needs

An increase in school-based health clinics is sweeping the states of Ohio and Michigan, following research that grounds positive health outcomes for ...

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Mar 21 • 8:00 PM EDT • Health • toledoblade.com
Arkansas vs High Point live updates: March Madness Round 2 game highlights, how to watch

We're running out of Cinderellas. Will the slipper still fit for High Point? Arkansas and Darius Acuff Jr. will have something to say about that.

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Mar 21 • 7:27 PM EDT • Sports • usatoday.com
79 Brilliant Memes That Brought Science And Humor Together

Let’s be honest—complex physics theories and mind-bending math problems can leave most of us staring blankly, wondering what just happened. But one thing most of us can understand is a good meme about them. Somehow, even the most complicated subjects become instantly relatable when they’re turned into a clever joke. And that’s exactly what we’ve got for you today, pandas. We’ve rounded up a bunch of science and math memes that take these “serious” subjects and give them a fun twist. You might no

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Mar 21 • 7:01 PM EDT • Science • aol.com
Illinois vs VCU live updates: March Madness Round 2 game highlights, how to watch

VCU's upset of North Carolina was a highlight of March Madness Round 1. What do Rams have in store for Illinois in Round 2? Follow our live updates.

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Mar 21 • 6:08 PM EDT • Sports • usatoday.com
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March Madness scores: Live updates, schedule for today's NCAA Round 2

Keep up with today's Men's NCAA Tournament second round with scores, highlights, game times and how to watch March Madness Round 2.

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Mar 21 • 4:15 PM EDT • Sports • usatoday.com
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Cowboys land top pass rusher in new mock draft

It feels inevitable that Dallas will take a pass rusher in the first round.

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Mar 21 • 3:00 PM EDT • Sports • sports.yahoo.com
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16 award-winning photographs from around the world

The Sony World Photography Awards announced the winning and shortlisted photographers of the 2026 National and Regional Awards .

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Mar 21 • 1:06 PM EDT • Science • popsci.com
Third-round draft prospects who can really help the Cowboys

Who do you want Dallas to draft with pick 92?

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Mar 21 • 1:00 PM EDT • Sports • sports.yahoo.com
Thousands race around sports complex for Phillies Charities 5K ahead of Opening Day
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Mar 21 • 12:27 PM EDT • Sports • cbsnews.com
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2026 NCAA Men's Basketball Tournament Highlights: Men's Round of 32, More

March Madness continues Saturday, and we've got you covered with all the must-see moments from start to finish!

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Mar 21 • 12:11 PM EDT • Sports • foxsports.com
Flood-prone Kīhei Crossroads for sale as its popular businesses remain closed from latest storm

In June of 2025, the popular strip shopping center near the Kīhei Canoe Club and the surrounding vacant land went on the market for $15.85 million.

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Mar 21 • 12:01 PM EDT • Business • mauinow.com
Crimson Desert Dev Promises Patch to Address 'Discomfort Many Players Have Experienced With the Controls,' Apologizes for Awful Keyboard and Mouse Experience

Crimson Desert developer Pearl Abyss has issued a message to players addressing complaints around the game’s controls, which have been widely criticized.

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Mar 21 • 11:30 AM EDT • Technology • ign.com
Ranking 5 most likely March Madness upsets in NCAA Tournament second round

The second round of 2026 NCAA Tournament is underway. Here's a look at the five most likely March Madness upset predictions in the Round of 32.

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Mar 21 • 11:20 AM EDT • Sports • usatoday.com
1 Clear Signal to Buy International Business Machines Stock Right Now

IBM has sold off because investors are worried about its software ties, but AI is more likely to help than hurt.

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Mar 21 • 9:15 AM EDT • Business • fool.com
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Cade Cavalli Looks to End Nationals Spring Training Losing Streak
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Mar 21 • 9:14 AM EDT • Sports • sports.yahoo.com
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Cowboys' 'Sneaky' New Contract? Dallas 'Won The Rashan Gary Trade'
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Mar 21 • 8:32 AM EDT • Sports • sports.yahoo.com
Duke vs. TCU odds, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Duke vs. TCU picks for the NCAA Tournament 2026 second-round game on Saturday

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Mar 21 • 8:32 AM EDT • Sports • cbssports.com
A massive freshwater reservoir is hiding under the Great Salt Lake

A hidden freshwater system deep beneath the Great Salt Lake has been revealed using airborne electromagnetic surveys. Scientists found that freshwater extends much farther under the lake than expected, reaching depths of up to 4 kilometers. The discovery began with mysterious reed-covered mounds formed by pressurized groundwater pushing upward. Researchers are now investigating whether this underground water could help control hazardous dust from the drying lakebed.

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Mar 21 • 8:00 AM EDT • Science • sciencedaily.com
Engadget review recap: Lots of Apple devices, Galaxy S26, Dell XPS 16 and more

A roundup of the latest reviews from Engadget.

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Mar 21 • 8:00 AM EDT • Technology • engadget.com
Science news this week: Super El Niño looms, an Acropolis marble fragment resurfaces, and a pure hexagonal diamond is born

March 21, 2026: Our weekly roundup of the latest science in the news, as well as a few fascinating articles to keep you entertained over the weekend.

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Mar 21 • 8:00 AM EDT • Science • livescience.com
The insular bubble of caucuses and assemblies

Nearly 30 years ago, then-Federal Reserve Chairman Alan Greenspan coined the term “irrational exuberance” to describe the overheated stock market. That descriptive phrase could also apply to much of the political realm. The hype in politics often grossly exceeds the reality on the ground. In that vein, let’s focus on Colorado’s precinct caucuses held earlier […]

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Mar 21 • 7:00 AM EDT • Politics • coloradopolitics.com