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Fewer bakers establish sustainability targets
In Baking & Snack’s latest study on sustainability, the lack of formal targets points to a shift in priorities when it comes to environmental reporting.
iPhone Duo Has Similar Main Camera to iPhone 17e
Apple's tech specs suggest the iPhone Duo's Main camera sensor is seemingly a match for the iPhone 17e's, not the standard iPhone 17's. According to Apple's tech specs page for the iPhone Duo, the Main camera is a 26mm, ƒ/1.6 sensor with sensor-shift optical image stabilization and Hybrid Focus Pixels, also enabling a 12MP 2x Telephoto crop from the same sensor.
New leaders emerge in Rhode Island as old guard falls in primary upsets
Taken together, the results amounted to a seismic shift in Rhode Island politics – a rejection of some of the state’s most established political figures and a striking signal that the electorate is ready for something new.
Haslams make major gift to West Side Market transformation
The $2.9 million gift will go toward a renovated event space and adding a second balcony to the Market Hall.
New measure captures how scientists’ identities shift across academic disciplines
Rice and Michigan State researchers have developed and validated a new way to measure the extent to which scientists remain closely connected to the core of their discipline over the course of their careers.
How geopolitical rifts cut scientific collaboration
Researchers have measured how worsening geopolitical relations hobble scientific collaboration, at last quantifying the impact of rifts between governments on cooperation between labs. Over the last decade, a tenser world has thrown up new barriers to cross-border science. Collaboration between the US and China has dimmed as the two countries have sunk into an ever-deeper rivalry. Links between Russia and Europe have collapsed following Moscow’s full-scale invasion of Ukraine. But while a concern, the magnitude of the damage is less than might be expected. For all the geopolitical turmoil of the last decade, international scientific collaborations are near a record high. “Some part of the story is positive,” said Shreyas Gadgin Matha, a social scientist at Harvard University and an author of the new study. “Research collaborations are largely resilient.” Matha and colleagues looked at data on cross-border research papers and patents in the period 2000-23, and analysed how they were impacted by countries’ political relations, as measured by how often states voted together in the United Nations. They found that when states drift apart at the UN by the median difference in votes between all countries, joint scientific papers decline by 3.1% over the next three-year period. To put that in context, over the last decade, the US and China have diverged by around a third of that difference in votes every three years. In other words, on average, it takes quite a significant diplomatic rift even to trigger a small single-digit percentage drop in joint papers. “In the short term, even something like a 3% reduction [in joint papers] is, in some ways, not that big of a number,” said Matha. Research remains more international than ever, according to an analysis extending to 2023 released by the Organisation for Economic Cooperation and Development (OECD) in 2025. We’re still living in an era of unprecedented scientific globalisation, the analysis says, with 27% of papers in OECD countries written across borders. In 1970, just 2% of articles had authors from different countries. Longer-term damage?However, this trend towards increasing international collaboration “has lost momentum and might be partly breaking down,” the OECD analysis says, largely due to a fall in the intensity of US-China joint papers since 2018. Matha and his colleagues stressed they are not complacent about the global science system. For now, “it's pretty resilient,” said co-author Muhammed Yildirim, director of academic research at Harvard’s Growth Lab. But if links are weakened, through the denial of study visas, for example, then this could have a much longer-term effect, cascading through generations of scientists, he added. Related articlesChina becomes Russia’s biggest collaborator after war decimates science ties with the west US scientists prefer German to Chinese collaborators, study finds Horizon Europe is now truly global. But what comes next? Another finding of the study, Burning bridges or bridging divides: Geopolitics and collaboration in research and innovation, is that trust appears easier to destroy than create.The hit to scientific collaboration when countries drift apart is around three times as big as the growth in joint papers when they move closer, the paper finds. “It's far easier to break these ties than to mend them, and that that also perhaps has some larger policy lesson,” said Matha.PatentsThe results around patents were less clear cut. Some methods of analysis found a statistically significant link between a diplomatic rift and a drop in co-patenting, but others did not. According to Yildirim, patents with cross-border inventors are often developed by multinational companies, which may have invested heavily in global R&D facilities, so are less likely to change how they operate simply due to a change in the geopolitical weather. “That's why we might not be seeing the effect immediately in technology,” he said.By contrast, researchers might be more sensitive to geopolitics, because visa policies can quickly affect who meets who at academic conferences, he went on. International collaboration on patents is much lower than for academic articles, the study shows. It peaked at around 10% in 2010, and has since fallen back to around 8%. This could be because China dramatically ramped up domestic patents in the 2010s, said Yildirim, squeezing the international share.
How geopolitical rifts cut scientific collaboration
Researchers have measured how worsening geopolitical relations hobble scientific collaboration, at last quantifying the impact of rifts between governments on cooperation between labs. Over the last decade, a tenser world has thrown up new barriers to cross-border science. Collaboration between the US and China has dimmed as the two countries have sunk into an ever-deeper rivalry. Links between Russia and Europe have collapsed following Moscow’s full-scale invasion of Ukraine. But while a concern, the magnitude of the damage is less than might be expected. For all the geopolitical turmoil of the last decade, international scientific collaborations are near a record high. “Some part of the story is positive,” said Shreyas Gadgin Matha, a social scientist at Harvard University and an author of the new study. “Research collaborations are largely resilient.” Matha and colleagues looked at data on cross-border research papers and patents in the period 2000-23, and analysed how they were impacted by countries’ political relations, as measured by how often states voted together in the United Nations. They found that when states drift apart at the UN by the median difference in votes between all countries, joint scientific papers decline by 3.1% over the next three-year period. To put that in context, over the last decade, the US and China have diverged by around a third of that difference in votes every three years. In other words, on average, it takes quite a significant diplomatic rift even to trigger a small single-digit percentage drop in joint papers. “In the short term, even something like a 3% reduction [in joint papers] is, in some ways, not that big of a number,” said Matha. Research remains more international than ever, according to an analysis extending to 2023 released by the Organisation for Economic Cooperation and Development (OECD) in 2025. We’re still living in an era of unprecedented scientific globalisation, the analysis says, with 27% of papers in OECD countries written across borders. In 1970, just 2% of articles had authors from different countries. Longer-term damage?However, this trend towards increasing international collaboration “has lost momentum and might be partly breaking down,” the OECD analysis says, largely due to a fall in the intensity of US-China joint papers since 2018. Matha and his colleagues stressed they are not complacent about the global science system. For now, “it's pretty resilient,” said co-author Muhammed Yildirim, director of academic research at Harvard’s Growth Lab. But if links are weakened, through the denial of study visas, for example, then this could have a much longer-term effect, cascading through generations of scientists, he added. Related articlesChina becomes Russia’s biggest collaborator after war decimates science ties with the west US scientists prefer German to Chinese collaborators, study finds Horizon Europe is now truly global. But what comes next? Another finding of the study, Burning bridges or bridging divides: Geopolitics and collaboration in research and innovation, is that trust appears easier to destroy than create.The hit to scientific collaboration when countries drift apart is around three times as big as the growth in joint papers when they move closer, the paper finds. “It's far easier to break these ties than to mend them, and that that also perhaps has some larger policy lesson,” said Matha.PatentsThe results around patents were less clear cut. Some methods of analysis found a statistically significant link between a diplomatic rift and a drop in co-patenting, but others did not. According to Yildirim, patents with cross-border inventors are often developed by multinational companies, which may have invested heavily in global R&D facilities, so are less likely to change how they operate simply due to a change in the geopolitical weather. “That's why we might not be seeing the effect immediately in technology,” he said.By contrast, researchers might be more sensitive to geopolitics, because visa policies can quickly affect who meets who at academic conferences, he went on. International collaboration on patents is much lower than for academic articles, the study shows. It peaked at around 10% in 2010, and has since fallen back to around 8%. This could be because China dramatically ramped up domestic patents in the 2010s, said Yildirim, squeezing the international share.
The first images of the Lego PlayStation’s free pre-order Lego Astro Bot gift have been leaked
It will reportedly be free with purchases of the PS1 set from the Lego website…
How September 11 Changed American Politics Forever
As the memory of the attacks faded, it was inevitable that counterterrorism measures would draw more scrutiny — and voter priorities would shift.
Ryan Garcia vs Conor Benn: The Narrative is Shifting
With just two days to go before this much anticipated clash for the WBC Welterweight title, new questions are being asked about the fighters' preparation
Workspace designs are starting to feel like home
Postpandemic office design trends are shifting from designing for utility to designing for human comfort, some Spokane-based interior designers say.
Climate solutions most likely to reach ‘positive tipping points’ revealed by scientists
Global shift towards clean electricity could trigger ‘cascade’ of progress, helping reduce air pollution, cut waste and revive oceans
Marquette gets $8 million planned gift for scholarships, business and athletics
Marquette University has received an $8 million planned gift from alumnus and longtime university volunteer Jim Meier, with the money earmarked for
Business news: New home for Mountain Tots, a new luxury real estate firm and a donation for river conservation
Vista Bank financing new home for Mountain Tots Preschool Vista Bank is financing the construction of a new home for Mountain Tots Preschool, a project that will expand licensed childcare capacity in Eagle County at a time...
Rhode Island could see a political wipeout next week
If Governor Dan McKee, Lieutenant Governor Sabina Matos, and Mayor Brett Smiley all were to fall, it would amount to an unprecedented upending of Rhode Island’s political establishment, and a massive rebuke that could signal a significant shift in the state’s political landscape.
Bears Gifted Massive Advantage Heading Into Regular Season
The Chicago Bears face the toughest schedule in the NFL, but they have it much easier than their opponents in another important way. The post Bears Gifted Massive Advantage Heading Into Regular Season appeared first on HEAVY.
Henry Winkler details rift with Tom Hanks over “Turner & Hooch” firing: ‘I am still working on my perspective’
“I guess at that time, being insecure, I talked too much,” the “Happy Days” star reflected.
Alaska continues rollout of Rural Health Transformation Program awards
Alaska Department of Health officials announced a fifth round of federal Rural Health Transformation Program funding awards on Friday. The latest awards for $25.8 million bring the total to more than $207 million to date.
Vendor applications open for Downtown Winter Farmers' Market
Vendor applications are open for the Downtown Winter Farmers’ Market, which will return to Capital Square in downtown Des Moines Nov. 20-22. Farmers, producers, makers and small businesses can apply to participate through Sept. 25. The three-day market, produced by the Downtown Farmers’ Market, will feature local food and gifts, live entertainment and food trucks…
NASA’s Swift Observatory Resumed Science Observations, At Least For Now
The satellite will be falling back to Earth within the next two months.
The data center backlash is reshaping Texas politics
By Texas Tribune Events Staff, The Texas Tribune August 28, 2026 Data centers are reshaping Texas communities, and the politics around them don’t break along familiar lines. On Wednesday, Sept. 9, The Texas Tribune convened a panel examining where Texans actually stand on the data center boom, how opinions are shifting and what it…
Utica University to screen 'Late Shift'
Utica University's Films on Thursday series will continue with a free screening of "Late Shift," a drama about nurse working in an understaffed hospital.
Mission Health's Mountain Area Medical Airlift marks 40 years of service
For four decades, Mission Health's Mountain Area Medical Airlift has taken to the skies to bring critical care across western North Carolina.
WA’s 26th Legislative District House race tests its political shift
The race for an open House seat in Washington's 26th Legislative District could test whether the district recent shift toward Democrats is enough to flip a seat Republicans have long held.
Taylor Swift becomes bugs
She’s a Grammy Award-winning international superstar, and now, Taylor Swift is also a genus of plant-feeding insects from Australia that were previously unknown to science.
Orlando Science Center brings back Cosmic Concerts laser shows
Cosmic Concerts returns to the Orlando Science Center in September, October, November, and December, and will feature music by Taylor Swift, U2, and Metallica. Here's what to know about tickets and schedule.
Market shift or seasonal shift?
Summer selling season ends with better news for buyers in NH’s residential real estate market
Trump gave $45,000 holiday gifts to Natalie Harp and two other White House aides
President Donald Trump gave sizable holiday gifts to four White House aides, according to new financial disclosures released by the administration.
Seager, Langford and Jansen homer to lift Rangers over Mariners 10-5
Corey Seager, Wyatt Langford, and Danny Jansen each hit a home run.
Labor Day rally held in Ellsworth
Uplifting workers was a key focus of Monday's Labor Day rally in Ellsworth, which featured multiple speakers, musicians and a march led by veterans down Main Street.
Why conservatives have shifted on Israel
The political formation of young conservatives is increasingly happening on the internet.
Science Applications International (SAIC) On Raised 2027 Guidance And Whether The Valuation Is Priced In
Why Science Applications International just moved into focus Science Applications International (SAIC) has landed on investor radars after reporting second quarter and six month results with higher sales and earnings guidance raised for fiscal 2027, shifting expectations for the business. Against that backdrop, Science Applications International has been in a steady uptrend, with the share price returning 26.01% year to date and 11.66% over the past 90 days. The 1 year total shareholder...
Zwift announces updated Ride V2 indoor smart bike, plus new in-game roads, bikes, events and cross-platform integrations
Everything coming this season on Zwift
Trump gave $45K holiday gifts to Natalie Harp and 2 other White House aides
A White House official said the cash gifts were not related to the "individuals' official government duties, and therefore are entirely permissible under relevant legal and ethical standards"
Mental health survey finds Yampa Valley residents struggle with loneliness, substance use disorders
The Steamboat Springs City Council heard a sobering assessment of behavioral health in the Yampa Valley on Tuesday: Despite strong awareness of local resources and a reputation for community support, many residents still face loneliness,...
Indiana counties' response to data centers reflects broader political risk
Indiana illustrates both the shifting political risk for data centers and the direction of the infrastructure finance discussion on this issue.
Trump Doled Out $45,000 Cash Gifts to Natalie Harp and Other Aides Last Year
The money, listed as “cash gift for the holidays,” was detailed in financial disclosure forms released by the administration.
Trump Doled Out $45,000 Cash Gifts to Natalie Harp and Other Aides Last Year
The money, listed as “cash gift for the holidays,” was detailed in financial disclosure forms released by the administration.
As science comes under attack at UN talks, climate movement splits over how to respond
A rift over how IPCC messages are produced and turned into policy is creating tensions in the world's most influential coalition of climate NGOs
Can Ohio business leaders shift data center opinions? Business leaders hope so
Ohio business leaders are launching a campaign to counter what they see as data center misinformation and convince skeptical communities that the facilities can be good neighbors.
An embattled Donald Trump is increasingly using sports as prop
Sports is the rare topic in which the president has succeeded in shifting the conversation to his preferred terms
Nonprofits Are Helping Musicians Pay for Insurance in Austin, Texas, and Beyond
A nonprofit and a local public health agency are subsidizing marketplace health insurance for Austin music artists, even as shifting marketplace conditions make the program a more expensive proposition. It’s becoming a model for other cities and sectors.
Did New Film Unit Just Shift AMC Stock’s Investment Narrative?
AMC Entertainment Holdings recently launched Leawood Films, a film distribution unit based in Los Angeles and Leawood, Kansas, aiming to bring more small and mid-sized movies into theatres worldwide while relying on fully financed projects to limit production risk. The new distributor uses AMC’s excess screen capacity and past concert-film marketing experience to secure theatrical placement for filmmakers who might otherwise struggle to find backing, while leaving most downstream revenue and...
Today’s Papers – Big Inter gifts, Juventus in trouble
La Gazzetta dello SportJuve, you need to get yourself blessed.Locatelli returns in 2027; stop for BogaAfter Yildiz and Thuram, the captain underwent surgery too (could be out for six months)Inter’s ...
Trump gave Natalie Harp and two other aides $45,000 each in cash gifts for holidays
President Donald Trump gave Natalie Harp and two other White House aides $45,000 each in cash gifts, according to financial disclosure statements.
Barcelona vs Feyenoord – Match preview and team news
Barcelona will aim to register their fifth straight victory this season when they kick off their UEFA Champions League campaign on Wednesday against Feyenoord at the Camp Nou.Barcelona vs Feyenoord �...
Barcelona vs Feyenoord – Predicted lineup and team news
Barcelona will be chasing a fifth consecutive win of the season as they begin their UEFA Champions League journey on Wednesday, hosting Feyenoord at the Camp Nou.FC Barcelona arrive in the competition...
The best business gifts aren’t the most expensive. They’re the most personal.
Louisville businesses are using engraved bourbon bottles to personalize corporate holiday gifts and strengthen client relationships.
Nebraska Senator Tanya Storer: Law requires brand committee members’ principal business ‘raising cattle’
Last week, the gubernatorial appointments to the newly restructured Nebraska Brand Committee were announced by the Governor’s Office. Under LB1187, the committee should be comprised of five district representatives plus one representative who owns or...
Trump gave $45,000 holiday gifts to Natalie Harp and two other White House aides
President Donald Trump has given substantial holiday gifts to four White House aides, according to financial disclosures released by the administration | 830 WCCO
Should the Chicago Bears extend D’Andre Swift?
Welcome to SB Nation Reacts, a survey of fans across the NFL. Throughout the year, we ask questions of the most plugged-in Bears fans and fans across the country. D’Andre Swift is in the final year of the three-year, $24 million contract he signed with the Chicago Bears in 2024, and before last season, no […]
Baylor finds confidence and belief despite loss to Auburn
WACO, Texas (FOX 44) — Baylor may have lost the battle on the scoreboard Saturday, but the Bears believe they gained something just as important in Atlanta: confidence. Despite a loss to Auburn, Baylor players said the game showed the team’s growing chemistry, physicality and belief heading into the rest of the season. Fifth-year cornerback […]
Taylor Swift Promoter Tells Judge Live Nationr Could Kill His Business
Louis Messina, tour promoter for Taylor Swift's Eras Tour as well as Ed Sheeran and other top acts, told a judge Live Nation has harmed his business.
Trump gave $45,000 cash gifts to Natalie Harp, two other close aides
Financial disclosures show the sums were equivalent to nearly one-third of each of their salaries. Experts say the gifts are without precedent and may violate the law.
Tiafoe escapes Michelsen to reach US Open semi-finals
Frances Tiafoe rallied from two sets down -- and 3-0 down in the fifth set -- to edge 22-year-old Alex Michelsen 5-7, 3-6, 7-5, 6-3, 7-6 (10/6) and reach the US Open semi-finals on Tuesday.But in a match of swinging momentum shifts, Tiafoe battled back from 5-3 down in the third set and recovered an early break in the fifth to reach his third US Open semi-final in five years.
Giants Officially Eliminated from Playoff Contention
Arizona’s Labor Day victory seals a fifth straight October without San Francisco, leaving Buster Posey to navigate a costly roster rebuild after a season defined by failure.
Making Sense of Phoenix Suns' Biggest Storyline This Season
As roster shifts trade elite shooting for raw athleticism, Phoenix faces a high-stakes gamble on Miles Bridges to elevate their ceiling amidst looming threats of early-season regression.
The trail of clues that our planet might be heating faster than we realised
A curious online row over this summer's heatwaves points to a wider - and worrying - shift in climate science.
The trail of clues that our planet might be heating faster than we realised
A curious online row over this summer's heatwaves points to a wider - and worrying - shift in climate science.
Council backs L.A. fast-food worker scheduling protections as businesses complain of tight margins
The Los Angeles City Council on Tuesday approved an ordinance to extend Fair Work Week scheduling rules to fast-food workers, adding predictable shifts and paid labor-rights training for tens of thous...
The 98 Biggest TV Show Flops, Bombs and Misses in the First Half of 2026
(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) In July, I updated my look at how the “streaming bubble” popped since 2023, showing the decline in streaming TV shows over time. But after compiling and analyzing and writing about over one hundred TV show flops in the first half of 2026—I counted 99 “nominees” and there are even more honorable mentions—I couldn’t have told you that the number of shows is going down. When it comes to scripted, English-language TV shows, it feels like we have as many bombs as ever. I don’t keep a specific count, but some streamers probably had as many flops as they’ve ever had.1 That’s right, it’s time for part two of my analysis of the biggest flops, bombs and misses on streaming in the first half of 2026. Two weeks ago, I took a look at films. Today, TV shows. If you want to read the full methodology for how I assemble this list, you can find it at the bottom of this article. In short, this list is… ...scripted and unscripted TV shows,...from the nine major streamers,...in the US (using US-only ratings),...excluding true crime, kids and foreign-language shows,...that got no/poor ratings,...from Jan-2026 to the end of June-2026. Reminder: this article does not represent my personal opinion—many of these shows are great!—but I follow the data, and a miss is a miss and a bomb is a bomb. Also, price matters. If a TV show costs north of $100 million, it needs to get lots and lots of streaming viewership to justify that budget. As with past editions, I ordered this list by streamer, going from best (fewest flops) to worst (the most misses)—taking the size of the flops into consideration—and like the last edition, three or four streamers vied to take the win/loss of having the most flops. (But the actual winner is no surprise.) I try to avoid tooting my own horn too much, but seriously, in just under 5,000 words (including the methodology section) I provide a mostly comprehensive overview of the eight major streamers (Netflix, Disney+, Prime Video, Hulu, HBO Max, Peacock, Paramount+, and Apple TV) for the first half of the year, mentioning most of their hits and all their misses. It summarizes the entire first half of 2026! If you want to support this work, please subscribe. Subscribe Tubi Big Mood Boarders The Freak Brothers Twenty Twenty Six Honorable Mentions: Busted on Bodycam, Deestroying the Pitch, Destination World Cup 2026 I don’t think that Tubi spends all that much making or (mostly) licensing these original TV shows—Big Mood, Boarders and Twenty Twenty Six all come from the UK—but they’re not free and they didn’t chart anywhere. Winner: The Freak Brothers Have you even heard of this show? It’s an animated comedy...that’s on its third season! And Pete Davidson, Woody Harrelson, John Goodman and Tiffany Haddish all provide voice talent for it. Yes, animated shows don’t cost as much as live action shows, but cheap isn’t free! So a show with this level of talent needs to perform better. Disney+ Daredevil: Born Again Star Wars: Maul – Shadow Lord Honorable Mentions: Behind the Attraction, Donna Hay Coastal Celebrations, We Call It Imagineering Disney+ doesn’t make all that many original shows anymore. They had two flops, and one was animated. Their one not-a-miss show, Wonder Man, got just good enough viewership to not be considered a “miss”...but it’s since been cancelled. At this point, Disney has pivoted entirely away from making big budget TV shows for Disney+ to making...almost nothing for Disney+? Sure, Disney’s spending circa 2019-2022 was unsustainable, but now they’re pivoting too far in the other direction. At some point, Disney needs to stop shifting strategies so wildly. Really, Disney should have made fewer shows for Disney+ at launch and the shows they did make at that time needed to be made at more reasonable budgets. And they should adopt that strategy now. Winner: Daredevil: Born Again Daredevil, the Marvel Comics character, is on my personal Mount Rushmore of favorite superheroes, so it pains me to give him the win/loss today, but this show deserves it. I’ll repeat my hot take from last spring: “Based on his popularity, Daredevil should be in movies, and probably ones that cost a lot less than the MCU’s usual price tag. Disney/Bob Iger/Ike Perlmutter (who, based on reporting, made the decision) made a huge mistake selling TV shows to Netflix in the 2010s, thus limiting this character to the small screen. Daredevil could have anchored Marvel’s post-Infinity War plans, and if he did, the MCU would probably be in a better place than it is now.” HBO Max We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… What four streamers had the most misses... HBO’s strong start to 2026… The caveat to Peacock’s turnaround this year... Paramount+’s key man problem… What country isn’t delivering hits for Netflix or Hulu... The cavalcade of stars on a streamer where no one is watching their shows... Across nearly 5,000 words of analysis… And a lot more... ...please subscribe! We can only keep doing this great work with your support. If you’d like to read more about why you should subscribe, please read this article about the Streaming Ratings Report, why it matters, why you need it, and why we cover streaming ratings best.
Fashion, food and fun combine to make this event a success
arc THRIFT STORES Denver News: “Let’s Celebrate” was the theme for arc Thrift Stores’ annual fundraiser, and it’s not a stretch to say that’s exactly what everyone did at this Sept. 3 gathering held at Denver Botanic Gardens. The crowd that filled the gigantic tent overlooking the UMB Amphitheater launched the celebration with a social hour where good conversations, along […]
Joint Observations with Swift removed from IXPE GO Cycle 4
The IXPE Guest Observer (GO) Program solicits proposals for investigations in any area of astrophysics (not constrained to IXPE’s prime science areas).
S&P 500 falls as AI worries hit software makers
The S&P 500 declined as AI competition fears hit software stocks and Middle East tensions lifted oil prices, with investors eyeing upcoming inflation data.
Dolphin Entertainment (DLPN) CEO now holds 547,190 shares after latest buy
CEO William O'Dowd IV bought 4,100 shares at a $1.19 average on Sept. 8, 2026 under a Rule 10b5-1 plan, lifting direct holdings to 547,190 shares.
Pittsburgh entrepreneur donates storage systems to Seton Hill business, technology school
The founder of a Pittsburgh-based digital storage solutions company donated $35,000 worth of equipment to Seton Hill’s cybersecurity and computer science programs. Gene Leyzarovich, former Jetstor CEO, founded the Bloomfield company more than 30 years ago while studying at the University of Pittsburgh and working night shifts at UPMC. The
Aspen School District renews membership with Valley Health Alliance
Valley Health Alliance announced today that the Aspen School District has renewed its membership, marking a significant milestone for both organizations.
DHR Health and RGV College Honor First-of-Its-Kind Nurse Apprenticeship Class
DHR Health and RGV College came together to celebrate the fifth co-hort of 10 graduates who completed the Registered Nurse Apprenticeship program.
DHR Health and RGV College Honor First-of-Its-Kind Nurse Apprenticeship Class
DHR Health and RGV College came together to celebrate the fifth co-hort of 10 graduates who completed the Registered Nurse Apprenticeship program.
COMMENTARY: Tennessee loses Dodson, shifts focus to Georgia Tech
What must Tennessee do to leave Atlanta with a win?
Monday Morning Minnesota: The “Slowly Drifting Away” Edition
So close, and yet so far.
Former MSU Interim AD Jon Palumbo Heading to Kentucky
The Spartans’ leadership exodus continues as another top executive reunites with J Batt in Lexington, leaving East Lansing to navigate a shifting front office after months of transition.
Foster Swift Welcome Hahn and Serra, Strengthens Business Law and General Counsel Services in Southeast Michigan
Attorney Marcy Hahn Attorney Lisa Serra SOUTHFIELD, Mich., Sept. 08, 2026 (GLOBE NEWSWIRE) -- Foster Swift Collins & Smith, PC is pleased to announce that attorneys Marcy Hahn and Lisa M. Serra have joined the firm's Southfield office, further strengthening its business law, corporate counseling, and general counsel capabilities throughout Southeast Michigan. Marcy and Lisa bring a unique blend of practices including fractional general counsel to business owners along with family law representat
Robinhood Lands Crypto.com Deal, Underwriting Job For Oura. Goldman Hikes Target.
Robinhood takes minority stake in Crypto.com with prediction market deal, to underwrite Oura IPO, reports say. Goldman lifts price target.
The shift in British policy on Israel is palpable
But progress could be threatened if there is a new more diplomatic government in Israel.
Haaland receives sixth Ballon d'Or nomination
Manchester City and Norway striker Erling Haaland has been named in the 30-player shortlist for the 2026 Ballon d'Or. The 26-year-old made 52 appearances across all competitions last season, scoring 38 goals and contributing nine assists, as Manchester City lifted the FA Cup and Carabao Cup. Haaland's new team-mate Ayyoub Bouaddi has also been nominated for the Men's Young Talent of the Year award.
USA TODAY Sports Super 25 national high school football rankings, Week 4
St. Thomas Aquinas' win over Columbus ensured Florida powers didn't shift in the Super 25, but teams from Texas and Georgia saw jumps after big wins.
‘Science at the Fifty-Third Degree’ humanizes research advancements through conversation
Episodes highlight the collaborative nature of science, and expand accessibility of discoveries happening at the university.
Roundup: Energy employment / Small business confidence / Maritime woes
Jobs in transition: Energy sector employment fell about 1% nationwide and in Louisiana from 2024 to 2025, with Louisiana losing 1,131 jobs to reach roughly 160,000 workers. The decline was driven largely by automation, policy changes affecting renewable energy, and shifting economics, while traditional energy industries such as coal and nuclear saw job growth. Despite […]
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
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