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Concerns and refinement but Chelsea are much-improved
Xabi Alonso left his last news conference in a subdued mood and wanting to conduct a "deeper analysis". It came after Alonso made four changes at half-time, introducing Cole Palmer, who scored twice, and Morgan Rogers, who provided four assists.
The core arguments behind the Rockstar union busting trial
Both parties have set out their stall in legal documents obtained by Game Developer.
These Memphis restaurants earned perfect health scores in August
Tennessee Health Department inspectors performed hundreds of health inspections in Shelby County in August. These 22 restaurants earned perfect scores.
York City v Swindon Town
Follow live text commentary, score updates and match stats from York City vs Swindon Town in the League Two
How concerned should big-spending Tottenham be after winless and goalless start to Premier League season?
Spurs are yet to win or score in the Premier League this season despite a big summer of spending; Roberto De Zerbis side also failed to have a shot on target last weekend; watch Tottenham vs Everton on Saturday, live on Sky Sports Premier League from 5pm; kick-off 5.30pm
High school flag football: Wednesday and Thursday scores
CIF City Section and Southern Section high school girls' flag football scores for Wednesday and Thursday.
Fenerbahce coach stuns players by resigning after Champions League draw
Ismail Kartal’s decision to quit caught many of his players by surprise, including goalscorer Archie Brown
Kyren Williams scores Rams' lone touchdown in Week 1 setback
Kyren Williams posted 65 yards and a score during the club's blowout loss to the San Francisco 49ers in Week 1.
Score Prediction: Does Michigan Have What It Takes Against Oklahoma?
Michigan will host Oklahoma on Saturday as the underdog and will need to be much better than they were last week to even be competitive.
Connections: Sports Edition today: Hints and answers for Sept. 11, 2026, puzzle No. 718
Welcome to Connections: Sports Edition Coach — a spot to gather clues and discuss (and share) scores.
Here are the iPhone 18 Pro and iPhone 18 Pro Max Geekbench scores
The A20 Pro delivers solid performance improvements compared to its predecessor. Yesterday, Apple unveiled the iPhone 18 Pro and iPhone 18 Pro Max, which...
Translating the Open Digital Ecosystem Principles to Business Transformation Strategy
ARC Advisory Group’s Open Digital Ecosystem Working Group outlines how open, governed, interoperable data foundations can support scalable digital twins, industrial AI, and measurable business transformation.
Manitowoc, Sheboygan Week 4 high school football scores, live updates
A live look at Week 4 high school football scores from around the Manitowoc and Sheboygan areas.
Como 1907 x RB Leipzig - Highlights, Summary and Match Report
Incidents: The story of the match1': The match beginsComo leads 1-0 against RB Leipzig. Martin Baturina scores for Como with a right-footed shot from the center of the box into the bottom left corner....
Massachusetts high school football scores (Thursday, Sept. 10)
The MIAA high school football season kicks off on Thursday, Sept. 10. Find all the opening-night scores here.
Minnesota-Mississippi State score predictions from Bring Me The Sports staff
The Gophers face a big test in Week 2 against the Bulldogs.
Live updates, scores from Week 4 of high school football
Follow along here for scores and highlights from Week 4 as Terry Sanford takes on Jack Britt, Seventy-First faces former coach at Hoke, and more.
St. Thomas Aquinas' Tyler Reid named USA TODAY Sports Super 25 Playmaker of the Week
Reid scored four touchdowns in St. Thomas Aquinas' top-10 win over Columbus.
NFIB Small Business Optimism Index falls slightly in August
The NFIB released its Small Business Economic Trends report for the month of August 2026, with the report showing a slight dip in Small Business Optimism, down 1.1 points from July 2026 to 98.7. In addition, the report showcased an Uncertainty Index score of 89 points, well above the average of 68 points. This number […]
Apple Watch Series 12 Ushers in New Health Sensing System, Oura-Like Readiness Score
Starts at $399
'Core' Discoveries; Hands-on apple science
Sarah Rushford from Ebenezer Child Care Centers shares simple ways to turn your apple-picking haul into at-home learning.
City & State New York Recognizes Three NYC Health + Hospitals Leaders on Its 2026 "Manhattan Power List 100" List
NYC Health + Hospitals/Metropolitan CEO Julian John, NYC Health + Hospitals/Harlem CEO Georges Leconte, and NYC Health + Hospitals/Bellevue CEO Dr. Eric
Ranking the Projected Fourth Line for the Kings in 2027
The projected third line for the Los Angeles Kings are Corey Perry, Joel Armia and Samuel Helenius. Here’s how each forward will rank based on expected production for next season.
Shorthanded No. 1 Stanford Faces Massive No. 3 Duke Challenge
A win would prove Stanford women's soccer can beat anyone. A loss would underscore how much the Cardinal are missing some of its top players.
New Art Exhibit at Juilliard Features 27 Works from the NYC Health + Hospitals Art Collection
New York, NY – NYC Health + Hospitals and Juilliard today announced a new exhibition at the school featuring 27 works from the health system’s art
What to Expect From Coby White This Season in Charlotte
Here is something worth knowing before worrying too much about what to expect from Coby White this season. In his 309 minutes with LaMelo Ball off the floor last season, Charlotte actually outscored opponents by 10.4 points per 100 possessions. What Charlotte Fans Should Expect From Coby White This Season The Hornets' true shooting percentage …
Eyewitness Sports Scoreboard for Thursday, September 10
As the first week of school comes to an end, the high school sports season goes into full swing!
New measure captures how scientists’ identities shift across academic disciplines
Rice and Michigan State researchers have developed and validated a new way to measure the extent to which scientists remain closely connected to the core of their discipline over the course of their careers.
Rams vs. 49ers live updates: Score, highlights, predictions, analysis
The Rams are hosting the 49ers in Melbourne today, their first game of the 2026 season. Follow along for live updates and analysis.
North Jersey high school football scoreboard: Week 2
Follow along with up-to-the-minute score updates and results from all of the high school football games across Bergen and Passaic counties.
Polytech CEO after acquisition: “It strengthens our core business”
In addition to strengthening its core business, the acquisition of Dansk Gummi Industri opens up new opportunities for Polytech. The CEO does not rule out further acquisitions.
Jaxon Smith-Njigba picks up where he left off
Despite the early switch from Sam Darnold (hip) to Drew Lock, Jaxon Smith-Njigba still topped 100 yards and scored Seattle's lone touchdown.
'Kroupi a bums off seats kind of player'
Former Bournemouth defender Joe Partington believes Eli Junior Kroupi has received "rightful recognition" after being nominated for the 2026 Ballon d'Or Men's Young Talent of the Year award. The 20-year-old, who is currently recovering from a broken foot, scored 13 goals in 35 appearances across all competitions last season. "It is just mad, isn't it?" Partington said on BBC Radio Solent's Cherries Unpicked podcast.
Niko Tsakris flashes class as San Jose rekindle winning ways
By Ben SteinerIf absence makes the heart grow fonder, then Niko Tsakris's return to the scoresheet must have felt pretty sweet on Wednesday night.Guiding the San Jose Earthquakes to a 3–2 win over C...
Portage County high school sports recaps for the week of Sept. 7-13
Check out our Portage County high school golf, soccer, tennis and volleyball scores and recaps for the week of September 7, 2026.
Memorial completes the comeback to beat North
EVANSVILLE, Ind. (WEHT) — After trailing 1-0 through the first half, Memorial boy’s soccer team scored two in the second half to beat North on the road. Next, the Tigers will host Castle on Wednesday, September 16th. While the Huskies face Washington at home on Saturday, September 12th.
Highlights/scores: College, high school sports (09/09/26)
CENTRAL ILLINOIS (WCIA) – Check out top plays, and various results from multiple different sports of different levels in Central Illinois from Wednesday, Sept. 9. University of Illinois volleyball picked up a straight-set win at home against Lindenwood. The Illini got a boost with 11 kills from Paityn Chapman, and 26 assists from setter Kenna […]
Connections: Sports Edition today: Hints and answers for Sept. 10, 2026, puzzle No. 717
Welcome to Connections: Sports Edition Coach — a spot to gather clues and discuss (and share) scores.
Big ninth inning stuns Canaries in game one
Sioux Falls, SD (CANARIES) – The Sioux Falls Canaries took a one-run lead into the ninth inning Wednesday night but Kansas City erupted for seven runs in the frame to sink the Birds 12-6 in game one of the West Division Series. Both teams scored a run without a hit in their half of the […]
Griezmann for the Heisman! Orlando's star rides scintillating scoring streak
By Harrison HammWith every Antoine Griezmann goal, optimism rises in Orlando. And so does the Lions’ place in the standings.Capping his fourth consecutive game on the scoresheet with a second straig...
What Florida Liked From the Defense in Week 1
Despite a dominant scoreboard victory, Florida’s coaching staff prioritizes correcting tactical errors and building defensive chemistry before high-stakes SEC play tests their young roster’s growth.
Core Growth Group Releases Plumbing Business Growth Strategies Guide for 2026
Core Growth Group is addressing 2026 growth pressures in the plumbing sector with new guidance on scaling beyond revenue gains, as workforce dem...
Arsenal: Martin Odegaard new role explained by Mikel Arteta after captain's Champions League winner at Napoli
Martin Odegaard scored his fourth goal in five games this season with the winner in Arsenals 1-0 Champions League victory at Napoli on Wednesday; Gunners captain only scored once in 2025/26 but higher position and fitness have facilitated fast start to the new campaign
Madison council rejects Willy Street business relief proposal
The proposal was tied to businesses still dealing with the aftermath of the Ruiz shooting.
Why didn't the Seahawks keep Kenneth Walker III?
The Seahawks spent big to keep their core together -- but that didn't include the reigning Super Bowl MVP.
'We could have scored more'
Norwich City boss Phillippe Clement speaks to BBC Radio Norfolk after the 2-1 win over Birmingham
A major weapon for Manchester City wiped out FC Porto
Erling Haaland scored a second-half brace to lead Manchester City to a 2-0 win over FC Porto at the Estádio do Dragão last night. Haaland endured a frustrating first half where Diogo Costa denied hi...
Georgia Tech’s Season Could Get Ugly Fast
Georgia Tech has a problem. The Yellow Jackets entered 2026 hoping to build off last season and potentially become a legitimate ACC contender. Instead, they’re 0-1 and already facing a massive game. Georgia Tech’s 14-13 loss to Colorado was ugly. The offense didn’t score a single touchdown, Tech managed just 51 rushing yards , committed…
💎 Lamine Yamal, Champions League's third-youngest free-kick scorer
Lamine Yamal makes it 4-0 for Barcelona against Feyenoord with his first direct free-kick goal in the Champions League. The stat is confirmed by MisterChip: at 19 years and 58 days old, the winger bec...
Apple's revamped Health app will calculate your 'health age' and readiness score
The update uses Apple Intelligence to make better sense of your health data.
Apple Announces a Redesigned Health App With Readiness Score
Apple's Health app has gotten several new features to help you keep track of your health and wellness.
Apple Unveils A20 Pro as First 2nm Smartphone Chip
Apple today revealed the A20 Pro chip in the iPhone 18 Pro and iPhone 18 Pro Max, built on a brand new architecture using 2nm process technology. Apple described the A20 Pro as "an exceptional chip that sets a new bar for mobile computing". The chip has a 6-core CPU design with two new super cores that Apple says are up to 20% faster, calling them "desktop class" and "the fastest in any smartphone," alongside four new efficiency cores.
Red Sox Minor Lines: Tanner Houck rehabs
Worcester, Game 1: L, 5-4 (BOX SCORE) With Greenville and Salem being done for the year, all eyes are on the teams closest to the Major Leagues as the Red Sox make a mad dash towards October. This year played out a bit differently, as many of the guys that may be able to make […]
Christie breaks new ground with hat-trick
Ryan Christie may not have been aware that he was making a little history while netting three times against Lincoln City in Bournemouth's Carabao Cup third-round tie. Tuesday's game was Bournemouth's 175th League Cup match since the competition was inaugurated in 1960, but Christie is the first Cherries player to score a League Cup hat-trick. Since his move to Dorset in 2021, Christie had found the net only 10 times for the Cherries before Tuesday, despite scoring six goals for his country in that same period.
Oklahoma @ Michigan Preview And Prediction
I’m not overthinking this one. Oklahoma is going to beat Michigan comfortably. The No. 11 Sooners travel to Ann Arbor on Saturday after completely destroying UTEP 51-0 in their season opener. Oklahoma scored on its first eight possessions, while John Mateer threw for 225 yards and three touchdowns. Michigan’s opener couldn’t have looked more different.…
Johnsonville Votes For Sausage Over Political Ads - Midland
Johnsonville has jumped back into electoral politics, this time asking people to vote for something sensible: affordable protein for dinner. The humorous campaign targets viewer fatigue, as record spending on political ads threatens to drain the fun out of every last game, sitcom and streaming pleasure. This time, the company is throwing its hat in the ring for Dinner 2026. Backed by research it conducted with Harris Polls, Johnsonville has learned Americans are already overwhelmed by both politics and meal planning. Sausage is running the dinner race on a core promise to simplify dinner decisions, the company says.
Valheim’s Metacritic Review Score Is In And Ties A 2026 Record
After being in early access for five years, Valheim is out and has a Metacritic review score at long last. Here's what it is.
East El Paso bakery receives near-failing health inspection score: List
See which El Paso restaurants earned perfect scores and which ones received a C grade in the latest health inspections.
Seager, Langford and Jansen homer to lift Rangers over Mariners 10-5
Corey Seager, Wyatt Langford, and Danny Jansen each hit a home run.
Encore Demonstrates Measurable Progress on Responsible Business Priorities
/PRNewswire/ -- Encore, a global leader in event production and technology, today announced the release of its 2026 Responsible Business Report, Illuminating a...
The Cost of Cutting American Science: How Federal Cuts Diminish Public Health Capacity
Among the federal government’s many responsibilities is the work it does to protect public health. Federal agencies monitor our food supply to ensure safety, conduct research to better understand emerging health threats, provide funding for public health programs in communities and work to detect and respond to disease outbreaks. Americans rely on these efforts every day—in a 2024 online survey, 74% of respondents said that “if the federal government issued safety guidance about food you eat regularly,” they would follow it. Changes to Federal Public Health Capacity The Trump administration’s efforts to reshape the federal government have resulted in significant impacts on our nation’s public health capacity over the past 20 months, affecting the response to health concerns such as measles, Ebola and cyclosporiasis. Agencies with core public health, food safety and disease prevention responsibilities experienced large workforce decreases during the first year of the administration. At the Centers for Disease Control and Prevention, for instance, the workforce in February 2026 was 26.7% smaller than in September 2024 before the start of the Trump administration. The Food and Drug Administration saw a similarly steep decline of 21.6%. Agencies such as the National Institutes of Health, Substance Abuse and Mental Health Services Administration and Food Safety and Inspection Service also experienced large workforce decreases. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); Changes can also be seen in crucial public health occupations. The number of federal food inspectors, for example, decreased by more than half between September 2024 and February 2026, going from 1,035 to 473. This is the lowest number of food inspectors employed by the federal government since at least 2005. By February 2026, there were also 33.3% fewer federal public health program specialists, whose work includes advising federal funding recipients on public health activities and analyzing the effectiveness of public health programs. Government’s capacity is diminished as employees with specialized knowledge and experience in protecting the public and responding to health risks depart, leaving agencies less prepared to carry out their public health missions. There also have been vacancies in critical high-level leadership positions at public health agencies, most notably at the CDC, which had a permanent Senate-confirmed director for less than a month between January 2025 and early August 2026. Although the CDC has previously been led by acting directors at the start of an administration, the nearly yearlong gap since the departure of the administration’s first permanent director in August 2025 is without precedent. As of August 2026, the FDA is also currently without a Senate-confirmed commissioner following the previous commissioner’s resignation in May 2026. Additionally, public health agencies are experiencing increased politicization of their leadership ranks. In agencies such as the CDC and Food Safety and Inspection Service, the number of individuals in the Senior Executive Service—the most senior career leaders in government—has declined significantly, while at the same time the number of political appointees has reached record levels. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); At the CDC, for example, the number of career SES decreased 42.9% between December 2024 and February 2026, while the number of non-Senate confirmed political appointees at the agency was six times larger than the agency’s historical average from 2009 and 2024. Knowledgeable career leaders are integral to the ability of public health agencies to carry out their work with scientific integrity and professional judgment, and rapid leadership turnover and increased politicization threaten agencies’ ability to make evidence-based decisions to protect our health. The upheaval and politicization in public health agencies have also negatively affected employee engagement. Strong employee engagement is crucial to the ability of agencies to carry out their mission and successfully provide essential services to the public. In the 2025 Public Service Viewpoint Survey conducted by the Partnership for Public Service, the Department of Health and Human Services—which encompasses major public health agencies such as the CDC and FDA—had an employee engagement and satisfaction score of 20.4 out of 100, one of the lowest among large agencies. Only 2.8% of HHS employees indicated trust in their political leaders and only 8.7% reported confidence that they could report a suspected violation of law or regulation without retaliation. Employees at HHS also reported that the agency’s ability to provide services to the public had suffered. Nearly half of employees at HHS, 47.5%, said their work unit was worse at delivering quality services compared to its performance in 2024. In addition, 57.8% said their work unit was performing worse at fulfilling stakeholder needs. In addition to the work done within federal agencies, the federal government also distributes significant funding for public health and disease prevention work to state and local governments, nonprofits and small businesses—funding which has been significantly disrupted. At the CDC, for example, there was a 71.9% decrease in the amount of project grant funding issued in fiscal year 2025 compared to fiscal year 2024. The FDA also issued far less funding in fiscal year 2025—a 21.3% decrease from its fiscal year 2024 funding. Changes in federal funding include the ending of grants to community organizations that worked on HIV prevention and the cancellation of funding for research into improvements to patient safety and healthcare quality. These changes go beyond federal agencies to impact the broader public health ecosystem, including the state and local health departments responsible for much of the on-the-ground public health work in their communities. About 80% of the CDC’s domestic funding is directed towards state and local partners—meaning that cuts to CDC funding can ultimately result in cuts to state and local public health capacity. Federal agencies also provide expertise and assistance to state and local health agencies as they deal with particular health challenges, but workforce cuts have resulted in fewer federal employees available to help. The Impact of Changes to Public Health Capacity These changes to federal public health capacity are not abstract concerns. Disrupted programs, reduced funding and lost expertise at public health agencies across all levels of government threaten the public’s physical well-being and safety. In some cases, this has already led to harm. The most immediate impacts of federal cuts were seen in interruptions to ongoing public health programs and crisis responses. In one instance, when CDC grants were canceled during the 2025 Texas measles outbreak—the most severe measles outbreak in 25 years—public health officials in Lubbock, Texas were forced to pause parts of their measles response work supported by the frozen funding. Lubbock’s director of public health further said that a lack of available CDC experts to reach out to for advice “definitely” impacted the department’s response to the measles crisis. Cuts to federal funding also forced Dallas County Health and Human Services to cut staff and cancel 50 community vaccination clinics during the outbreak. Public health work outside of major outbreak responses was also disrupted. For example, in April 2025, the Milwaukee Public Health Department was unexpectedly unable to reach experts on lead poisoning due to firings at the CDC when responding to concerns about lead contamination in Milwaukee public schools. Due to federal workforce cuts, several programs at the CDC, including Alzheimer’s and epilepsy programs, have also become trapped in limbo—existing on paper, but without the staff necessary to operate. More recent crises reveal how federal cuts have weakened the public health infrastructure needed to prevent and respond to dangerous new outbreaks. Internationally, cuts at the U.S. Agency for International Development eliminated funding for disease testing and contact tracing abroad, which delayed detection of and responses to the 2026 Ebola outbreak in the Democratic Republic of Congo. While international outbreaks may seem far removed, the unchecked spread of disease in any country can quickly pose a danger to economic well-being, security and health around the world. Within the United States, public health cuts inhibited responses to the summer 2026 outbreak of the food-borne parasite cyclospora. At the federal level, cuts to funding for lab equipment and for CDC staff with expertise in parasitic infections—including 9 out of 11 staff members at the lab responsible for identifying parasitic outbreaks in 2025— contributed to the largest reporting delay in outbreak cases at the CDC in 15 years. Conflicting communications from the FDA about the source of the outbreak, which followed cuts to the agency’s communications department, additionally led to confusion among the public about how to best avoid infection. At the same time, cuts to HHS funding and support for local and state public health slowed some health departments’ responses to the crisis. The exact costs of these delays, constraints and confusion in public health responses are difficult to estimate. However, their message is clear: federal cuts have already made containing threats to public health even more of a challenge. Conclusion Protecting public health—from food safety to disease prevention—is one of the federal government’s most important missions. Dramatic and haphazard cuts to federal agencies and funding have already disrupted the public health system, impacting the response to challenges such as measles, lead poisoning and cyclosporiasis. The U.S. public health system needed improvement before these disruptions. Since 2022, federal leadership and coordination in response to public health outbreaks has been on the Government Accountability Office’s High-Risk List of areas in need of attention to improve government effectiveness and efficiency. Recent cuts only compound these concerns. The chaotic dismantling of government and resulting disruptions to crucial functions like public health and disease prevention highlight the need for meaningful reform and concrete policy proposals to reimagine how government can better serve the public and be more effective, responsive and accountable. To learn more about the impact of federal cuts to public health and science more broadly, visit The Cost of Cutting American Science. Learn more For more information on the Partnership for Public Service’s government reform initiative, visit Government for a New Era. View here In line with The Cost of Cutting American Science, federal workforce data in this brief is as of February 2026
The Cost of Cutting American Science: How Federal Cuts Diminish Public Health Capacity
Among the federal government’s many responsibilities is the work it does to protect public health. Federal agencies monitor our food supply to ensure safety, conduct research to better understand emerging health threats, provide funding for public health programs in communities and work to detect and respond to disease outbreaks. Americans rely on these efforts every day—in a 2024 online survey, 74% of respondents said that “if the federal government issued safety guidance about food you eat regularly,” they would follow it. Changes to Federal Public Health Capacity The Trump administration’s efforts to reshape the federal government have resulted in significant impacts on our nation’s public health capacity over the past 20 months, affecting the response to health concerns such as measles, Ebola and cyclosporiasis. Agencies with core public health, food safety and disease prevention responsibilities experienced large workforce decreases during the first year of the administration. At the Centers for Disease Control and Prevention, for instance, the workforce in February 2026 was 26.7% smaller than in September 2024 before the start of the Trump administration. The Food and Drug Administration saw a similarly steep decline of 21.6%. Agencies such as the National Institutes of Health, Substance Abuse and Mental Health Services Administration and Food Safety and Inspection Service also experienced large workforce decreases. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); Changes can also be seen in crucial public health occupations. The number of federal food inspectors, for example, decreased by more than half between September 2024 and February 2026, going from 1,035 to 473. This is the lowest number of food inspectors employed by the federal government since at least 2005. By February 2026, there were also 33.3% fewer federal public health program specialists, whose work includes advising federal funding recipients on public health activities and analyzing the effectiveness of public health programs. Government’s capacity is diminished as employees with specialized knowledge and experience in protecting the public and responding to health risks depart, leaving agencies less prepared to carry out their public health missions. There also have been vacancies in critical high-level leadership positions at public health agencies, most notably at the CDC, which had a permanent Senate-confirmed director for less than a month between January 2025 and early August 2026. Although the CDC has previously been led by acting directors at the start of an administration, the nearly yearlong gap since the departure of the administration’s first permanent director in August 2025 is without precedent. As of August 2026, the FDA is also currently without a Senate-confirmed commissioner following the previous commissioner’s resignation in May 2026. Additionally, public health agencies are experiencing increased politicization of their leadership ranks. In agencies such as the CDC and Food Safety and Inspection Service, the number of individuals in the Senior Executive Service—the most senior career leaders in government—has declined significantly, while at the same time the number of political appointees has reached record levels. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); At the CDC, for example, the number of career SES decreased 42.9% between December 2024 and February 2026, while the number of non-Senate confirmed political appointees at the agency was six times larger than the agency’s historical average from 2009 and 2024. Knowledgeable career leaders are integral to the ability of public health agencies to carry out their work with scientific integrity and professional judgment, and rapid leadership turnover and increased politicization threaten agencies’ ability to make evidence-based decisions to protect our health. The upheaval and politicization in public health agencies have also negatively affected employee engagement. Strong employee engagement is crucial to the ability of agencies to carry out their mission and successfully provide essential services to the public. In the 2025 Public Service Viewpoint Survey conducted by the Partnership for Public Service, the Department of Health and Human Services—which encompasses major public health agencies such as the CDC and FDA—had an employee engagement and satisfaction score of 20.4 out of 100, one of the lowest among large agencies. Only 2.8% of HHS employees indicated trust in their political leaders and only 8.7% reported confidence that they could report a suspected violation of law or regulation without retaliation. Employees at HHS also reported that the agency’s ability to provide services to the public had suffered. Nearly half of employees at HHS, 47.5%, said their work unit was worse at delivering quality services compared to its performance in 2024. In addition, 57.8% said their work unit was performing worse at fulfilling stakeholder needs. In addition to the work done within federal agencies, the federal government also distributes significant funding for public health and disease prevention work to state and local governments, nonprofits and small businesses—funding which has been significantly disrupted. At the CDC, for example, there was a 71.9% decrease in the amount of project grant funding issued in fiscal year 2025 compared to fiscal year 2024. The FDA also issued far less funding in fiscal year 2025—a 21.3% decrease from its fiscal year 2024 funding. Changes in federal funding include the ending of grants to community organizations that worked on HIV prevention and the cancellation of funding for research into improvements to patient safety and healthcare quality. These changes go beyond federal agencies to impact the broader public health ecosystem, including the state and local health departments responsible for much of the on-the-ground public health work in their communities. About 80% of the CDC’s domestic funding is directed towards state and local partners—meaning that cuts to CDC funding can ultimately result in cuts to state and local public health capacity. Federal agencies also provide expertise and assistance to state and local health agencies as they deal with particular health challenges, but workforce cuts have resulted in fewer federal employees available to help. The Impact of Changes to Public Health Capacity These changes to federal public health capacity are not abstract concerns. Disrupted programs, reduced funding and lost expertise at public health agencies across all levels of government threaten the public’s physical well-being and safety. In some cases, this has already led to harm. The most immediate impacts of federal cuts were seen in interruptions to ongoing public health programs and crisis responses. In one instance, when CDC grants were canceled during the 2025 Texas measles outbreak—the most severe measles outbreak in 25 years—public health officials in Lubbock, Texas were forced to pause parts of their measles response work supported by the frozen funding. Lubbock’s director of public health further said that a lack of available CDC experts to reach out to for advice “definitely” impacted the department’s response to the measles crisis. Cuts to federal funding also forced Dallas County Health and Human Services to cut staff and cancel 50 community vaccination clinics during the outbreak. Public health work outside of major outbreak responses was also disrupted. For example, in April 2025, the Milwaukee Public Health Department was unexpectedly unable to reach experts on lead poisoning due to firings at the CDC when responding to concerns about lead contamination in Milwaukee public schools. Due to federal workforce cuts, several programs at the CDC, including Alzheimer’s and epilepsy programs, have also become trapped in limbo—existing on paper, but without the staff necessary to operate. More recent crises reveal how federal cuts have weakened the public health infrastructure needed to prevent and respond to dangerous new outbreaks. Internationally, cuts at the U.S. Agency for International Development eliminated funding for disease testing and contact tracing abroad, which delayed detection of and responses to the 2026 Ebola outbreak in the Democratic Republic of Congo. While international outbreaks may seem far removed, the unchecked spread of disease in any country can quickly pose a danger to economic well-being, security and health around the world. Within the United States, public health cuts inhibited responses to the summer 2026 outbreak of the food-borne parasite cyclospora. At the federal level, cuts to funding for lab equipment and for CDC staff with expertise in parasitic infections—including 9 out of 11 staff members at the lab responsible for identifying parasitic outbreaks in 2025— contributed to the largest reporting delay in outbreak cases at the CDC in 15 years. Conflicting communications from the FDA about the source of the outbreak, which followed cuts to the agency’s communications department, additionally led to confusion among the public about how to best avoid infection. At the same time, cuts to HHS funding and support for local and state public health slowed some health departments’ responses to the crisis. The exact costs of these delays, constraints and confusion in public health responses are difficult to estimate. However, their message is clear: federal cuts have already made containing threats to public health even more of a challenge. Conclusion Protecting public health—from food safety to disease prevention—is one of the federal government’s most important missions. Dramatic and haphazard cuts to federal agencies and funding have already disrupted the public health system, impacting the response to challenges such as measles, lead poisoning and cyclosporiasis. The U.S. public health system needed improvement before these disruptions. Since 2022, federal leadership and coordination in response to public health outbreaks has been on the Government Accountability Office’s High-Risk List of areas in need of attention to improve government effectiveness and efficiency. Recent cuts only compound these concerns. The chaotic dismantling of government and resulting disruptions to crucial functions like public health and disease prevention highlight the need for meaningful reform and concrete policy proposals to reimagine how government can better serve the public and be more effective, responsive and accountable. To learn more about the impact of federal cuts to public health and science more broadly, visit The Cost of Cutting American Science. Learn more For more information on the Partnership for Public Service’s government reform initiative, visit Government for a New Era. View here In line with The Cost of Cutting American Science, federal workforce data in this brief is as of February 2026
Who are the record Champions League goalscorers?
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Orlando-area Week 4 high school football scoreboard
Here is the schedule and scoreboard for Week 4 games for Orlando area high school football teams. Home teams are on the bottom line. Rankings are from the Sentinel Super 16. Check back often, as scores will be updated as games progress. Super 16 Coaches Poll: DeLand football returns to unanimous No. 1 status Varsity content editor Buddy Collings can be contacted by email at ...
Brugge win 'can't be underestimated'
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UE falls in physical match against a ranked Louisville team
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Baker Mayfield Agrees to Extension After ‘Disrespectful’ Buccaneers Offer
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Center For Family Health Sports Scoreboard
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Flyers Confirm Major New Arena News
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Haaland double powers Man City to victory over Porto
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A-State sets fall enrollment record
Arkansas State University has set another fall enrollment record, reaching 18,775 students as continued growth among Arkansas freshmen, improved student retention, and rising graduate enrollment helped push the university past...
A-State sets fall enrollment record
Arkansas State University has set another fall enrollment record, reaching 18,775 students as continued growth among Arkansas freshmen, improved student retention, and rising graduate enrollment helped push the university past...
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AMID POLITICAL AD BOMBARDMENT, SAUSAGE DECLARES ITS CANDIDACY… FOR DINNER
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AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Adley Rutschman's three-run HR off Pesky Pole carries Red Sox past Angels, 5-2
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Factory Entertainment Announces New STRANGE NEW WORLDS, VOYAGER, and STAR TREK IV Prop Replicas
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Monumental Sports & Entertainment reaches multi-year deal with bet365
Your best source for quality Washington Wizards news, rumors, analysis, stats and scores from the fan perspective.
School students who use AI chatbots score lower in OECD science test
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