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40 looters ransack family-run California business during massive street takeover
Surveillance video shows 40 suspects ransacking A-Z Market in Bellflower after power tools were used to breach the security gate during a street takeover.
Five Omaha business leaders will attempt to climb Mount Kilimanjaro for housing initiative
Five Omaha business leaders will attempt to reach the summit of Mount Kilimanjaro to raise money for five new Abide homes to be built.
Healthcare Access Out of Reach for Many Older, Noncitizen Immigrants | Johns Hopkins Bloomberg School of Public Health
Federal policies will narrow options for many who already report lacking insurance, access to care, and concerns about paying medical bills.
Global health tech competition aims to accelerate innovation improving cardiovascular and brain health
DALLAS, Aug. 18, 2026 — Despite rapid advances in digital health, artificial intelligence and remote patient monitoring, many promising health technologies still fail to reach patients who need them most. To help close that gap, the American Heart...
UnitedHealth shareholders sue company over ‘corporate governance failures on a historic scale’
The lawsuit was filed by two major institutional investors who blame company leadership for the 2024 breach on Change Healthcare and accuse executives of facilitating alleged Medicare billing fraud.
How much will the Yankees’ offense improve?
Can the Yankee offense find the heights it reached earlier this season?
The New Love Center and River Valley Health partner for Food Pharmacy
The New Love Center and River Valley Health held a ribbon cutting ceremony to celebrate the launch of their Food Pharmacy, a partnership with the goal of delivering nutritious foods to clients using the facility. The project had been in the works for roughly six months when River Valley Health reached out to The New […]
Little Italy Days helps businesses expand its reach beyond Bloomfield
Little Italy Days brought 200-plus vendors and more than 100,000 visitors to Bloomfield, giving Botta Biscotti a wider customer reach
U.S. school vaccination rates inch down again as exemptions reach record high
It’s the fourth consecutive year that the national average exemption rate has reached a new record, and the vast majority are parents withholding shots for nonmedical reasons.
Ask Pinstripe Alley: Yankees mailbag questions request
The Yankees are at a crossroads with the playoff race reaching a fever pitch.
US midterm election betting races past 2024 congressional total, data shows
The group forecast that total wagers on the 2026 midterms could reach $1.6 billion if betting activity accelerates at the same pace as it did in 2024.
Europe strengthens its network of social sports schools and surpasses 2,000 beneficiaries
The Real Madrid Foundation developed 34 social sports projects in eight European countries during the 2025-26 season, reaching 2,053 children and...
Burnham exchanged messages with person posing as Trump's chief of staff
Downing Street has declined to comment on the security breach, first reported by Politico.
Trump threatens to bomb Oman if it 'gets in the way' of US-Iran talks
President Trump threatened military action against US ally Oman if its negotiations with Iran interfere with U.S. efforts to reach a deal with Tehran.
Unlocking KRAS: Turning Science into Survival
Thanks to the dedication of generations of scientists and researchers, we’ve reached a tipping point where KRAS has been unlocked. PanCAN has been and will continue to be the backbone of this effort.
Apple Devices That Are Reaching The End Of Software Support In 2026
The list of Apple devices that will fall out of software support in 2026 includes gadgets across four categories: Apple Watch, iPad, Mac, and Apple TV.
Packers, Bears reach out to Menasha football team following tornado
Green Bay Packers host Menasha Bluejays at training camp practice; Menasha coach gets supportive call from Bears owner George McCaskey.
Did WEBTOON Entertainment Inc. Insiders Breach their Fiduciary Duties to Shareholders?
/PRNewswire/ -- Halper Sadeh LLC, an investor rights law firm, is investigating whether certain officers and directors of WEBTOON Entertainment Inc. (NASDAQ:...
One-of-a-kind business in Champaign celebrates first anniversary
CHAMPAIGN, Ill. (WCIA) — A unique business in Champaign reached new heights with its first anniversary on Sunday. Horizon Climbing was packed with people celebrating, scaling rock-walls and t…
Roma optimism grows over move for Porto talent Rodrigo Mora
Roma are increasingly optimistic about reaching an agreement with Porto for highly-rated youngster Rodrigo Mora after stepping up their efforts to sign the Portuguese talent.According to Corriere dell...
"Marvel's Spider-Man: Beyond Amazing" reaches last day at Griffin Museum of Science and Industry
Sunday was the last chance for visitors to see the "Marvel's Spider-Man: Beyond Amazing" exhibition at the Griffin Museum of Science and Industry.
Hollywood duo underline Premier League ambition for Wrexham
Ryan Reynolds and Rob McElhenney, the Hollywood owners of English second-tier side Wrexham, have restated their ambition for the club to win the Championship title and so complete a remarkable journey from National League to the Premier League.Deadpool star Reynolds said he felt "obscene pride" at Wrexham's league finish and co-owner McElhenney has underlined their determination to reach the top flight after playing in the fifth tier of English football as recently as 2023.
Freed American missionary ‘in good health’ after captivity in Niger
World Outreach Church Pastor Allen Jackson says freed missionary Kevin Rideout is a ‘bright voice for Christianity’ on ‘Saturday in America.’
Djokovic feels the heat in Cincinnati opening defeat
Novak Djokovic suffered in the second set from punishing heat and humidity on Saturday but made a match of it before falling 2-6, 6-4, 6-4 to Argentine Thiago Tirante in what could be the Serb's last appearance at the ATP-WTA Cincinnati Masters. Martin Landaluce beat Matteo Arnaldi 6-4, 4-6, 6-4 to reach a third-round clash against Tirante.
'Mission' review: George MacKay is transcendent in this fever dream about living
Paul Wright's subversive drama sees the "Rose of Nevada" star reach his limit.
Patriots reach injury settlement with running back Terrell Jennings
Terrell Jennings landed on injured reserve before the preseason opener.
Five remaining US detainees in Russia facing dire health concerns, horrific treatment: Gilman family rep
Kieran Ramsey, Chief Investigative Officer for Global Reach and a former FBI hostage recovery expert details the declining health of five Americans in Russian detention, arguing all five must be given wrongful detainee status.
Vikings HC Kevin O’Connell Has Strong Justin Jefferson Message
Justin Jefferson still reached the 1,000-yard mark last season, but it was anything but a smooth year for the Minnesota Vikings star. The inconsistent play at quarterback took a toll on Jefferson’s production, leading some to rule him out as the best wideout in the NFL.During the 2025 campaign, Jefferson played 392 pass snaps for […] The post Vikings HC Kevin O’Connell Has Strong Justin Jefferson Message appeared first on HEAVY.
Measuring Whether Behavioral Health Crisis Systems Reach People in Need
Since passage of the American Rescue Plan Act in 2021, the United States has made significant investments in behavioral health crisis response systems,
Scientists thought Titan was hiding a global ocean beneath its frozen crust. But a 2025 reanalysis of Cassini data points to something stranger instead — a roughly 380-kilometre-thick layer of slushy ice, close to melting and likely threaded with pockets of liquid water that could reach 20°C near the rocky interior.
A 2025 Cassini reanalysis measures a tidal lag that favors a warm, partly melted high-pressure ice layer over Titan's long-assumed global ocean.
FBI seized devices from Guggenheim CEO Mark Walter, top deputy: report
Federal scrutiny of the Chicago-based investment giant reached Walter and Guggenheim President Dina DiLorenzo months before Walter struck a $12.5 billion deal to sell the Lakers.
Jeremy Strong reveals this about Mark Zuckerberg movie 'Social Reckoning'
Jeremy Strong has revealed he reached out to Mark Zuckerberg, and received a response back, before playing the Facebook entrepreneur in the upcoming movie "The Social Reckoning."
Aesto Health Data Security Incident Affects Multiple Healthcare Provider Clients
A data breach at Aesto Health, a Birmingham, Alabama-based healthcare technology company, has affected several of its healthcare provider clients. Aesto A security incident at the Alabama healthcare technology company Aesto Health has affected at least 27 of its healthcare provider clients and exposed the protected health information of hundreds of thousands of patients.
NFL WAGs at Practice Are Part of Coordinated Content Rollout
The moments are part of a coordinated content rollout to reach women.
Apple Warns Users in 110 Countries They May Be Targets of Mercenary Spyware
Apple alerts suspected mercenary spyware targets in 110 countries, expanding threat notifications that have reached users in over 150 countries.
Anthropic’s $2 trillion problem: Its underlying business is nowhere near the IPO valuation it wants
Everything you need to know before you reach the office this morning.
Attacks on healthcare in conflict zones averaging more than four a day in 2026, World Health Organization says
Attacks on healthcare facilities, workers and patients in conflict zones including Ukraine and Gaza have continued to rise in 2026, reaching an average of more than four per day, the World Health Organization said on Friday.
Skanska small business outreach lead sees opportunity in DBE changes
After hitting hiring goals on a Los Angeles International Airport project, DBE compliance officer Teresa Maxwell outlined how the firm connects with contractors local to its projects.
The Atlantic Ocean can handle more warming than expected
Scientists have found that the AMOC may be far more vulnerable to rapid warming than to temperature alone. When warming happens slowly, the ocean can adapt, but at faster rates similar to today’s, the massive Atlantic circulation could reach a tipping point at much lower temperatures.
HHS Announces Historic Investment to Expand Health Center Program, Bringing Primary Care to Nearly 1 Million More Americans
HHS announced $102 million in New Access Points awards to significantly expand the reach of the Health Center Program.
Voters prefer socialist over MAGA candidate in 2028 matchup: Poll
New polling released this week suggests that a socialist candidate would defeat a Make America Great Again candidate in a hypothetical 2028 presidential matchup, a move that implies the reach of progressive leftists isn’t abating despite recent setbacks in Wisconsin. If the 2028 election for president were held today, 55% of respondents said they would […]
Experience Science City's KidFEST
Lead Outreach Educator Jordan Fox joins Shane and Kerrigan to share what you can expect from KidFEST at Science City.
Walmart just made a major business move — and surprisingly, it has nothing to do with groceries
Walmart is expanding its reach beyond groceries and retail into a new market. Here's what's behind the move.
Pokemon Bank is shutting down, announcement released
Today, The Pokemon Company announced that it’s shutting down Pokemon Bank. The service goes offline on February 26, 2027. Once we reach that day, players will not be able to transfer Pokemon from Pokemon Bank to Pokemon Home. It will not be possible to store Pokemon there any longer. Players are advised to send their creatures to Pokemon Home before...
Explore Our Women’s Sports Report
Download the full report to learn what makes the women’s sports audience unique and how your brand can reach them.
Highway 92 redesign in Platte City moves forward despite business owner concerns over access
For months, business owners along Highway 92 in Platte City have raised concerns that a new median and the elimination of left turns could make it harder for customers to reach them.
‘The Gentlemen’ ransomware gang takes over hospital Facebook after cyberattack
AnMed, a nonprofit health system, suffered a data breach in late July that has left some of its systems still offline. Now, an infamous hacker group is claiming credit for the attack in an unusual way.
Highland Health Systems; Albany Gastroenterology Consultants Settle Data Breach Lawsuits
Settlements have received preliminary approval to resolve class action data breach complaints against Highland Health Systems and Albany Gastroenterology Settlements have received preliminary approval to resolve class action data breach complaints against Albany Gastroenterology Consultants and Highland Health Systems stemming from breaches of patient data.
The US is now using the ‘terrorist’ label to interfere in Brazil’s election
The designation of PCC and CV serves to expand Washington’s reach into the country’s politics and security.
Asia-Pacific parliamentarians urge bolder action for universal health coverage, climate resilience and responsible AI
Parliamentarians representing 16 countries from across the Asia-Pacific region concluded the Ninth Meeting of the Asia-Pacific Parliamentarian Forum on Global Health (APPFGH) today, reaffirming their key role in advancing universal health coverage (UHC) amid the risks and opportunities posed by AI and climate change. In adopting the Phnom Penh Communiqué, parliamentarians urged fellow legislators regionwide to strengthen sustainable financing for UHC to widen access to health for all, including the most vulnerable populations; promote responsible governance of AI amid ethical concerns over this fast-evolving technology; and build climate-resilient health systems to anticipate and respond to mounting pressures ranging from rising sea levels in coastal areas to air pollution and other environmental degradation.The National Assembly of Cambodia, with support from Cambodia’s Ministry of Health and the World Health Organization (WHO), hosted the Forum in Phnom Penh from 11 to 13 August 2026 – the first time the Forum has convened in a Mekong country.Parliamentarians urge action to close gaps in accessIn the Communiqué, parliamentarians recognized that at-risk and marginalized groups are the ones most severely affected by gaps in access to health services. These groups include people living in poverty, women and children, persons with disabilities, older people, migrants, refugees, and those in rural, remote or island communities. The Communiqué urges fellow parliamentarians and policy-makers to advocate for laws and policies that support sustainable financing to protect people from financial hardship, with a focus on primary health care, prevention and equity. "The Communiqué is a call to action. It sets out ambitious, concrete measures that deliver meaningful impact on the ground. We are all accountable for advancing universal health coverage and translating our commitments into tangible results. Cambodia is fully committed to advancing UHC, including the promotion of ‘healthy people, prosperous country’ campaign,” said Samdech Maha Rathsapheathika Thipadei Khuon Sudary, President of the National Assembly of the Kingdom of Cambodia.His Excellency Professor Chheang Ra, Minister of Health of the Kingdom of Cambodia, highlighted the need for collaboration beyond the health sector. “Universal health coverage cannot be achieved by the Ministry of Health alone. It requires support, particularly from parliamentarians, across political, legislative, financial, social protection, education, infrastructure, and environmental domains. While each country follows its own path, one factor is universally critical for success: strong governance and leadership. We all believe in this principle, and in our respective political roles, we remain committed to strengthening these key success factors to ensure that no one is left behind.”Promoting responsible AI adoption Parliamentarians acknowledged that, while AI has already demonstrated its ability to improve access to health services and support delivery, careful and ethical governance is necessary to safeguard quality, safety, privacy and public trust. This underscores the importance of parliamentarians in promoting legal and regulatory frameworks addressing liability, records ownership and data governance, while embracing innovation that protects ethical practice.“Without strong governance, safeguards for privacy and data security, sustainable financing, and attention to those most at risk of exclusion, new technologies may widen existing gaps instead of closing them. This is why parliamentarians matter. We pass laws. We approve budgets. We scrutinize government action. We represent communities. We can ask whether health services are reaching rural, remote, ageing, poor, and marginalized populations. We can ask whether innovation is being guided by equity, evidence, and ethics,” said Hon. Man Hee Lee, President of the Asia-Pacific Parliamentarian Forum on Global Health.Building climate-resilient health systemsParliamentarians also reiterated that the climate crisis is a direct threat to people’s health and to achieving UHC more broadly, deepening the same gaps in access already faced by at-risk and marginalized communities. They recognized the need for WHO Member States to ensure sufficient national appropriations and oversight, and for parliamentarians to raise awareness in their constituencies and mobilize local action in building climate-resilient and sustainable health systems.“Universal health coverage, climate change and AI cannot be addressed in isolation. The same communities struggling to access health services today are often the ones most exposed to climate shocks, and most in need of the opportunities AI can offer if this technology is governed responsibly,” said Dr Saia Ma’u Piukala, WHO Regional Director for the Western Pacific. “Having served previously in this Forum myself as a parliamentarian from Tonga, I recognize how the Phnom Penh Communiqué reflects the shared resolve of legislators across the Asia-Pacific region: the laws parliamentarians pass and the budgets they approve help ensure this progress reaches the people who need it most.”As the Forum drew to a close, delegates reflected on what they would carry back to their own parliaments and constituencies.“I wish to share three points here worth carrying home from Phnom Penh: we need to invest in primary health care as the foundation of coverage; we need to remove the barriers that keep people from care, whether financial, geographic or social; and we need to build systems that are inclusive by design, protecting those most at risk of being left behind,” added Hon. Ouch Borith, First Vice-President of the Senate of the Kingdom of Cambodia.###Notes for editors:The Asia-Pacific Parliamentarian Forum on Global Health (APPFGH) is a platform for parliamentarians to exchange ideas, build political will, strengthen capacity and foster collaboration towards sustainable health action. This was the ninth meeting of the APPFGH, with the theme “Universal Health Coverage in the era of Climate Change and Artificial Intelligence”. Target 3.8 of the Sustainable Development Goals calls on countries to achieve universal health coverage, including financial risk protection, access to quality essential health services, and access to safe, effective, quality and affordable essential medicines and vaccines for all. In the Western Pacific, UHC service coverage index (SDG 3.8.1) rose from 63 in 2000 to 81 in 2023 (figures include Indonesia), and roughly one in four people in the Western Pacific have experienced financial hardship (SDG 3.8.2). Progress towards UHC in the Asia-Pacific region remains uneven, with hundreds of millions of people still lacking access to essential health services or facing financial hardship due to health-related expenses. Strengthening the role of parliaments – through legislation, financing and oversight – is central to closing this gap and accelerating progress towards UHC across the region.Parliamentarians participating in APPFGH in Cambodia this week include: Hon. Pehin Dato Adanan YUSOF, Brunei Darussalam; Hon. Rosmawatty ABDUL MUMIN, Brunei Darussalam; Hon. LORK Kheng, Kingdom of Cambodia; Hon. YOS Phanita, Kingdom of Cambodia; Hon. KHOUN Khundy, Kingdom of Cambodia; Hon. HENG Halim, Kingdom of Cambodia; Hon. KHOENG Noupheap, Kingdom of Cambodia; Hon. SENG Nhak, Kingdom of Cambodia; Hon. LY Sukry, Kingdom of Cambodia; Hon. NHOEURN Raden, Kingdom of Cambodia; Hon. Dr Ratu Atonio LALABALAVU, Republic of Fiji; Hon. Vijay NATH, Republic of Fiji; Hon. Man Hee LEE, Republic of Korea; Hon. Dr Jiho CHA, Republic of Korea; Hon. Jonghun BAEK, Republic of Korea; Hon. Youngsuk SEO, Republic of Korea; Hon. Dr Phayvanh KEOPASEUTH, Lao People’s Democratic Republic; Hon. Suhaizan Bin KAIAT, Malaysia; Hon. Dr Perpetua KONMAN, Federated States of Micronesia; Hon. Ganmaa DAVAASAMBUU, Mongolia; Hon. Charmaine SCOTTY, Republic of Naoero; Hon. Vincent Ambance KUMURA, Papua New Guinea; Hon. Dr Edwin CRUZADO, Republic of the Philippines; Hon. AUUAPAAU Mulipola Aloitafua Mulipola, Samoa; Hon. ASIATA TAVUI Tafu Salevao, Samoa; Hon. Dr Alani Petelo TANGITAU, Tonga; Hon. Paul PAOLO, Republic of Vanuatu; Hon. Franklyn Ezra WILLIAM, Republic of Vanuatu.For more information, contact: WHO Regional Office for the Western Pacific: wprocom@who.int National Assembly of the Kingdom of Cambodia (International Relations Department): ir.nacambodia@gmail.com
Business incubator coming to downtown Houghton in 2028
The city is encouraging entrepreneurs to reach out if interested in using a space in the building.
Starting QB Revealed for Browns Preseason Opener with Bears
The Cleveland Browns QB competition reaches it's next phase as the team faces the Chicago Bears in their preseason opener. But who will start?
MIT selected to lead new NSF materials research center
The National Science Foundation selected MIT to establish a Materials Research Science and Engineering Center to develop materials for medical imaging, sustainable metals production, and next-generation electronics. MRSEC will also launch outreach programs exploring the role of materials in society and the lessons learned from materials failures.
Cyberattacks on US water systems raise alarms, but Congress faces hurdles on a fix
After recent cyberattacks targeted water systems, local leaders are urging Congress to boost protections before a more serious breach disrupts drinking water supplies.
15M patients impacted by largest healthcare data breach of 2026
DentaQuest, the second-largest dental benefits administrator in the U.S., suffered the record-setting cyberattack in May. A notorious ransomware gang has taken credit for the attack.
Whoop CEO Will Ahmed on Medicare expansion: 'We're excited about where the business is going'
Whoop CEO Will Ahmed discusses the wearable technology company's expansion into CMS Medicare, reaching over 3 million members, and launching natural cycles integration on 'Mornings with Maria' with Maria Bartiromo.
De'Zhaun Stribling Continues Turning Heads at 49ers Training Camp
The San Francisco 49ers took a lot of heat when they drafted wide receiver De'Zhaun Stribling in the second round of the 2026 draft. The consensus on Stribling was that he should be a third-or-fourth-round pick. Instead, the 49ers took the Ole Miss product in the second, and many immediately called it a reach.
Myles Lewis-Skelly transfer news: Chelsea and Man Utd turn down intermediary offer to sign Arsenal teenager
Latest transfer news and headlines as Newcastle are exploring a move for Benfica right-back Amar Dedic; Aston Villa have reached a verbal agreement to sign Matteo Ruggeri from Atletico Madrid; Kyle Walker is a target for Everton; Paul Pogba is set to leave Monaco
Microsoft Patches 398 Flaws Including a Windows Driver Zero-Day Under Active Attack
Microsoft patches 398 flaws, including exploited CVE-2026-68820 that lets local attackers reach SYSTEM, plus four unauthenticated 9.8 RCEs.
Colorado puts new limits on sports betting as wagers soar
The rules aim to curb harmful gambling practices as sports betting reaches record highs.
How smoke in the atmosphere impacts your health
Smoke from massive wildfires burning in the Pacific Northwest has reached central Nebraska, pushing air quality index readings higher than normal and prompting health warnings for at-risk residents.
Joby Aviation builds out defense business with $500M acquisition
Joby Aviation reached an agreement to acquire Resonant Sciences, which will kick off its new defense business.
Digital Twin in Entertainment Market to Reach USD 2,533.2 Million by 2032, Growing at 31.4% CAGR, Says MarketsandMarkets™
Delray Beach, FL, Aug. 11, 2026 (GLOBE NEWSWIRE) -- The global Digital Twin in Entertainment Market is projected to grow from USD 492.4 million in 2026 to USD 2,533.2 million by 2032, at a CAGR of 31.4%, according to a new report by MarketsandMarkets™. Growth is being driven by increasing adoption of virtual production technologies, rising investments in immersive entertainment experiences, and expanding deployment of AI-powered digital twin platforms across film, television, gaming, live events
College sports bill doesn’t get vote, but does get spot on the Senate’s September calendar
The Protect College Sports Act failed to reach a vote during an all-night, pre-recess session in the Senate that ended early Saturday, though the bill did gain a spot on next month’s calendar after the chamber comes back from its summer break.
Lionsgate: Filmed Entertainment Backlog Jumps 21% To $1.5 Billion As Library Revenue Approaches $1 Billion
Lionsgate Studios' filmed entertainment backlog increased 21% year-over-year to $1.5 billion during its fiscal first quarter of 2027, while trailing 12-month library revenue reached $987 million as the company’s existing film and television catalog becomes an increasingly important source of recurring cash flow.
Can we make sense of today's politics by reaching into the community?
Disagreements about our values and hopes will be hard conversations, but we, as people, cannot walk away from having them.
WHO receives US$4 million from CERF to sustain health services and strengthen health system resilience across Syria
Damascus, Syrian Arab Republic, 11 August 2026 – The World Health Organization (WHO) has received US$4 million from the United Nations Central Emergency Response Fund (CERF) to protect access to essential health...
Democratic rebellion against older politicians reaches new battleground
Former Hartford Mayor Luke Bronin, 47, is challenging Rep. John Larson, who is 78 and running for his fifteenth term representing Connecticut's first district.
Health Sciences outreach program helps amplify the voices of people with aphasia
The UK College of Health Sciences is helping people with aphasia reconnect with their communities by partnering with local businesses and organizations to create more communication-friendly spaces. Through a unique outreach program, students work alongside individuals with aphasia to educate employees, reduce communication barriers and make everyday experiences more accessible and welcoming.
Why LA Council chief says Nithya Raman reached ‘political bottom of barrel'
Council President Marqueece Harris-Dawson says despite Raman’s claims that she’s being punished for running for mayor against Karen Bass, she knew about her committee assignment change. Conan Nolan reports for the NBC4 News at 7 p.m. on Monday, Aug. 10, 2026.
Treacherous waters await the Gophers in Big Ten play
A 6-3 record will be easier said than done for Minnesota
HeyDay Entertainment to close Norman location after selling to Oklahoma Turnpike Authority
HeyDay Entertainment announced on Monday that it will be closing its Norman location on August 28 after reaching an agreement to sell its property to the Oklahoma Turnpike Authority for planned hig…
Ted Cruz’s college sports bill left in limbo as U.S. Senate takes August recess
Sen. Ted Cruz’s bill to place new regulations on college sports failed to reach the floor this week, imperiling its chances to become law this year.
HeyDay Entertainment to close Norman location after sale to OTA
HeyDay Entertainment announced Monday that it will close its Norman location to the public Aug. 28 after reaching an agreement to sell the property to the Oklahoma Turnpike Authority for
Funding Science for the Long Term: The Role of Private Philanthropy
A drug that reaches a pharmacy shelf today often rests on discoveries made decades earlier. Yet the institutions financing scientific research do not
A data breach at shipping giant Ceva Logistics is rippling across banks, retailers, Steam gamers, and beyond
Companies that rely on Ceva Logistics for shipping their physical goods to customers say their personal data was taken during a recent cyberattack.
Dan Campbell Reveals Jared Goff’s Next Big Step
Dan Campbell says Jared Goff has reached another level as a quarterback, with greater urgency, command and leadership for the Detroit Lions.
Steam hardware shipper breach leaks customer data, including names and addresses
Valve says customer data was “likely compromised.”
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice
AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.
Unipol seeks over 30% of future BPER-MPS business
The insurer has reached an agreement to purchase a business made up of about 635 MPS branches.
How should states reach out to Medicaid enrollees affected by changes? Our research gives a hint
Experts ask: How can we better reach out to people facing Medicaid renewal deadlines and support them through the paperwork requirements?
Starwatch: Deep partial solar eclipse in UK to precede the Perseids
The eclipse will begin just after 6pm on 12 August, reaching its maximum just over an hour later
Misiorowski Becomes Second Fastest Pitcher to 200 Strikeouts
The Milwaukee Brewers’ flamethrower trails only Spencer Strider in the record books for the fewest innings pitched to reach 200 strikeouts in a single season.
Ted Cruz’s college sports bill left in limbo as U.S. Senate takes August recess
U.S. Sen. Ted Cruz’s bill that would place sweeping new regulations on college sports failed to reach the floor this week before the Senate gaveled out for recess, imperiling its chances to become law this year as the midterm elections approach.
Which Suns Player Will Reach the Hall of Fame Next?
As Amar’e Stoudemire prepares for induction, the focus shifts to whether Chris Paul’s leadership, Shawn Marion’s unique versatility, or Devin Booker’s scoring dominance will secure the next call.
Eagles preach patience as Makai Lemon continues to battle hamstring injury
The Eagles' 2026 first-round pick has missed four consecutive practices.
Tigers' Jackson Jobe: Reaches 100.1 mph in return
Tigers' Jackson Jobe: Reaches 100.1 mph in return
Spanish teen Jodar ousts eighth seed Lehecka at Montreal
Spanish teen Rafael Jodar defeated Czech eighth seed Jiri Lehecka 6-3, 6-3 on Saturday to reach the quarter-finals of the ATP Montreal Masters.Jodar will play for a semi-final berth against French 18th seed Arthur Fils, who defeated Britain's Cameron Norrie 6-2, 7-6 (10/8).
Data shows only 14% of England's waters are in good health, and none are chemical-free
England may need almost 40 years to reach good chemical status.
Chemists set electrons free and break a decades-old chemistry barrier
Chemists have developed a catalyst that breaks a long-standing rule governing which molecules receive electrons during chemical reactions. By releasing electrons directly into solution, the technique could unlock reactions—and potentially useful new molecules—that were previously out of reach.
Padres' Fernando Tatis: Reaches double-digit homers
Padres' Fernando Tatis: Reaches double-digit homers
Senate vote on college sports bill slated for September
The Protect College Sports Act failed to reach a vote during an all-night, pre-recess session in the Senate, though the bill did gain a spot on next month's calendar after the chamber comes back from its summer break.
College sports bill doesn't get vote, but does get spot on the Senate's September calendar
The Protect College Sports Act failed to reach a vote during an all-night, pre-recess session in the Senate, though the bill did gain a spot on next month’s calendar after the chamber comes back...
Scientists warned US funding turmoil could reach Woods Hole. Now WHOI is cutting jobs.
Woods Hole is nicknamed \
Tigers' Kevin McGonigle: Reaches four times in loss
Tigers' Kevin McGonigle: Reaches four times in loss
Marlins' Kyle Stowers: Reaches base five times Friday
Marlins' Kyle Stowers: Reaches base five times Friday
ECU Health-UnitedHealthcare deal restores in-network care for 100,000+ in ENC
ECU Health and UnitedHealthcare have reached a new multi-year contract agreement, restoring in-network access for more than 100,000 patients across eastern Nort
ECU Health reaches new multi-year agreement with UnitedHealthcare to restore in-network access for patients
ECU Health has reached an agreement on a new multi-year contract with UnitedHealthcare, restoring in-network access to care.