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New proposal would cap Social Security benefits at $100K for wealthy couples
A new proposal from the Committee for a Responsible Federal Budget would cap Social Security benefits for wealthy couples at $100,000 annually, with a $50,000 limit for single retirees.
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Older adults who regularly engaged in exercise sessions lasting at least 10 minutes at a leisurely pace had healthier brains than their sedentary peers, accordi
She taught backyard swim lessons. A single complaint shut them down.
Local governments should encourage home businesses instead of making them illegal.
Scientists Call for a Complete Rethink of Alzheimer’s Treatment
New insights suggest that Alzheimer’s cannot be tackled through a single pathway, as its roots extend across molecular, genetic, and systemic processes.
Russia breaks record, launches nearly 1,000 strike drones in a day
Ukraine said it shot down 906 out of 948 long-range drones launched into its borders within a single 24-hour window.
Super Mario Bros. Wonder + Meetup In Bellabel Park Review
Mario Wonder's Switch 2 upgrade adds neat single-player content, but the real draw is the massive array of multiplayer party games.
Did Scientists Overestimate AI’s Ability To Think Like Humans?
A new wave of AI research is attempting to tackle one of psychology’s oldest questions: whether the human mind can be unified under a single theory.
Paranovus sells 14.3M shares at 35 cents to raise $5M
A single institutional investor agreed to buy the shares, with closing set for about March 25. Paranovus says net proceeds will fund working capital.
Apple Combines Business Offerings on Single Platform
Apple has introduced a platform that brings together several of its business offerings. Dubbed “Apple Business,” the platform will be launched April 14 in
Billionaire OpenAI investor Vinod Khosla thinks 80% of jobs could vanish by 2030, and that ‘fear of AI’ put American politics in a chokehold
“The single biggest issue I believe in the 2028 presidential election will be fear of AI,” the Khosla Ventures founder said.
Marathon has sold 1.2M copies across Steam, PS5, and Xbox
Alinea Analytics estimates show that Marathon has generated gross revenues of $55M via 1.2M copies sold on Steam, PS5, and Xbox: Looking at the split between Steam, PS5, and Xbox, Steam is clearly the main platform for Marathon, accounting for a little under 70% of the audience (800K copies sold). Meanwhile, PS5 takes about 19% (217K) and Xbox (including console, PC, and cloud) accounts for a bit over 11% or 133K. Marathon is technically a first-party Sony title, so seeing the home console struggle to break 20% of the volume is a notable data point for the ongoing platform-agnostic debate. PlayStation Studios online games will almost certainly continue being multiplatform (despite Sony reportedly pulling back on PC releases). Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe As for Marathon, the consensus among hardcore players who pushed through the awkward onboarding phase – myself included – is that it’s fantastic. The gunplay, aesthetic, and presentation are among the best in the shooter genre. A great game doesn’t always equal an immediate hit, though, as shown by our estimates. Things are looking lukewarm right now. But this might be one of those marathon-not-a-sprint situations. Had to, didn’t I? Why wasn’t Marathon a hit on the same level as Arc Raiders? One topic that came up in a lot of conversations at GDC this year was why Marathon hasn’t hit the same stratosphere as Arc Raiders. On paper, they’re both extraction shooters, and Marathon has the Bungie pedigree – the house that built the gold standard for gunplay in Halo and Destiny. Marathon’s neon-futuristic aesthetic also distinguishes itself from the gritty realism of Tarkov or the post-apocalyptic hope of ARC Raiders. But vibes can only get you so far for first impressions if the onboarding feels like a brick wall. Marathon is a sweaty PvP-focused experience with a first-time user experience and UI that I can only describe as dreadful. Players are dropped into a complex ecosystem where the UI, though visually striking, is functionally uninformative, forcing users to manually hover over nondescript, identical icons just to identify basic gear or weapon mods. This lack of clarity is compounded by punishing mechanics like a severe heat gauge for movement and a scarcity of vital resources, all without a clear tutorial or a low-stakes mode to learn the ropes. Most people – even top streamers and veteran shooter players – have no idea what’s going on in Marathon at first. Arc is on the complete other end of the spectrum. As we covered here and here, Arc Raiders offers a more collaborative, approachable loop where players often work together toward shared goals. And the objectives are instantly clear. To many players, this contrast only emphasised Marathon’s issues, especially during the testing period. Players understand the Arc Raiders loop within 30 minutes, while Marathon acts as a massive filter, chewing up newcomers and spitting them out before they can experience the depth of Bungie’s signature gunplay. What I’m getting at here is that the poor first-time user experience of Marathon’s Server Slam likely stifled launch sales, while the opposite was true for Arc. Let’s look at the pre-launch copies sold for each game during their respective Server Slams (launch-aligned) : Looking at the trajectory: Arc Raiders saw a massive 80% jump in copies sold during its three-day Server Slam (day -13 to -11). Players jumped in, realised the water was fine, and immediately opened their wallets. Marathon, meanwhile, saw a 49% increase in the four days following its Slam (Day -7 to -3). At the time of each game’s respective launch, Arc Raiders had nearly double the Steam footprint of Marathon – and word of mouth only continued to grow. Bungie could have had more time to fix the onboarding process had the beta happened earlier. But Marathon launched three days after the beta finished. These factors limited the launch sales quite a bit, I reckon. Marathon has found a niche audience, though Despite the friction-heavy start, the data suggests that those who survived Marathon’s onboarding are loving life. We’ve been tracking cross-platform DAUs, and while there’s the expected post-launch leakage, many players are sticking with it. After peaking at 478K total DAUs on its first Saturday, Marathon has settled into a respectable rhythm, holding 345K DAUs as of yesterday and averaging 380K DAUs across the weekend. Steam continues to do the heavy lifting here, consistently accounting for the lion’s share of the daily players. Players have been putting in the hours, too: On Steam, Marathon’s average playtime has climbed to 27.8 hours, significantly outpacing the console averages on PS5 (16.5h) and Xbox (17.3h). Even more telling than the averages: 22% of the Steam audience has surged past the 50-hour mark, and nearly 7% have already logged over 100 hours. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe This data suggests that once the Bungie magic clicks, it hooks players deeper than the average extraction shooter. There’s also started to be a shift in the game’s discourse. Marathon launched as one of those games that’s cool to hate. But as Marathon’s 100-hour club grows, we’re seeing conversations around its mechanical merit outweigh the negativity. Several high-profile creators, who were initially vocal critics, have spent the last week coming around on the mechanical depth of the endgame. It’s a subtle but positive signal; the hate train is losing steam, and a new narrative about the game is emerging. Bungie faithfuls unite Another interesting metric in Marathon’s first few weeks is who, exactly, is playing. Bungie leans heavily on its prestige as the “makers of Halo and Destiny,” in its marketing, and that message has clearly hit the mark. On Steam, the gravity (hammer) of Bungie’s previous work is unavoidable. A staggering 78.2% of Marathon players also played Destiny 2. The trend carries across other platforms, with 74.2% of PS5 players and 82.7% of Xbox players also having played Destiny 2. The Halo legacy lives on, it seems. More on that in a bit. While Destiny 2 went free to play, these numbers still represent a high-intent migration of a fanbase that trusts Bungie’s specific brand of kinetic gunplay and cryptic world-building. The Xbox data adds another layer of legacy. About 85.7% of Marathon players on Xbox have played Halo Infinite, while over half of the Steam audience has spent time in Halo Infinite and 36.1% in the Master Chief Collection (a paid collection of the old Bungie-made legacy games). Interestingly, we see a 55.9% overlap with ARC Raiders on Steam. Overlap is even higher there on PlayStation (60.5%) and Xbox (66.5%). And there’s also significant crossover with Helldivers 2 on all platforms, too. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe Bungie has found some of its fans with Marathon, and the challenge now is keeping this engaged in a high-stakes PvP environment when they’ve spent the last decade primarily enjoying the power fantasies of PvE. On that note… Go the full 26 miles? Or cut and run? Time for some could’ve, should’ve, would’ve. These things would have improved Marathon’s performance at launch: A more robust onboarding process, perhaps in the form of a short single-player/PvE campaign. We know Bungie fans love this stuff. A traditional arena-based mode akin to Destiny’s Crucible could have been a bridge for the cautious players who’d have been otherwise deterred by the Server Slam. It’s also a great palate cleanser after getting merked. Introducing a dedicated PvE environment would have similarly diversified the conversation and lowered the barrier for the Bungie faithful who found the pure PvP extraction loop too abrasive. PvE is safer than PvP these days. There’s an argument that a thin PvE mode would have just felt like a budget Destiny, potentially hurting the brand more. But given how dire the FTUE is, I think it would have been a net positive. Any kind of tutorialised loop that demystifies the stakes, really. While there is merit in a studio sticking firmly to a singular creative vision, and going all in on the hardcore extraction loop. Less forgiving is the technical reality is that the user interface and first-time user experience (FTUE) were not at a commercial standard for launch. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe In a landscape where player time is oversaturated and the most contested currency, a flawed FTUE is a critical failure point. But it’s not all doom and gloom, as Marathon has an incredible, unique gameplay loop, suggesting that financial success is still attainable if Bungie can pivot effectively. Bungie and PlayStation now face a difficult strategic crossroads, though – one within a challenging games market. They could: Double down on Marathon with a long-term Rainbow Six Siege- or No Man’s Sky-style recovery plan, which is something I heard Last Stand Media’s Chris Maldonado mention last week. While this could be a sunk-cost fallacy in action, it could eventually yield the audience the game’s mechanical depth deserves. Shift focus toward the inevitable Destiny 3 or another project, mitigating the escalating opportunity cost and cutting their losses, so to speak. Doing both is an expensive proposition, given the high overhead and burn rate of operating out of Bellevue, Washington. With Sony recently demonstrating a lower threshold for underperforming studios and projects, the margin for error has vanished. Whatever happens, the next six months will determine whether Marathon becomes a cornerstone of Sony’s live-service portfolio or a cautionary tale of vision exceeding accessibility. I’m hoping it’s the former, because Marathon rocks. As always, hit subscribe to get updates on Marathon and other relevant games. Subscribe Want to get your hands on our data for yourself – for free? We’re offering a free trial of our platform for games companies. Send us a message here, or reply to this email, and we’ll set you up. The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]
Mouse study shows repeated cloning causes grave genetic mutations
1,206 cloned laboratory mice were generated by the scientists from a single female donor mouse from 2005 to 2025 in research conducted in Japan.
These Creatures Have One Cell and No Brain. Scientists Just Discovered They Can Learn.
In 1897 Russian physiologist Ivan Pavlov proved that animals can be trained using associative learning. A new study finds that even single-celled organisms can behave like “Pavlov's dog.”
From One Major to Three in Four Years: Connecting Data Science, German and Linguistics at Montclair
In a German language program for local children and on an archive translation project, Isabella Zarate Gonzalez shows how Montclair’s mix of STEM, world languages and community engagement helped her connect her interests into a single path
While Intel Skipped Core Ultra 9 290K Plus, It Appeared At Geekbench With A Staggering 17% Higher Single And Multi-Core Score Than Ultra 9 285K
Intel's Core Ultra 9 290K Plus scores 3747 single-core and 26117 multi-core in Geekbench, showing a 17% performance boost over the 285K.
Bucks, Clippers still hoping to make playoff runs
The Los Angeles Clippers will welcome an old friend back into town Monday when former head coach Doc Rivers and his current team, the Milwaukee Bucks, make a visit to Inglewood, Calif.
UTA College of Business to connect students, professionals with networking, elevator pitch event
Students, business professionals and recruiters will mingle from 6 to 8 p.m. Monday at the UTA Center for Entrepreneurship and Technology Development.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Arizona softball walks off ASU to even series
Arizona softball earned a walk-off win over ASU Saturday night, though not the kind the Wildcats may have been expecting through the first part of the game. Arizona jumped out to an 8-0 lead, then allowed the Sun Devils to claw all the way back before Regan Shockey delivered a walk-off single in the seventh […]
Scientists just found a hidden 48-dimensional world in quantum light
A routine quantum optics technique just revealed an extraordinary secret: entangled light can carry incredibly complex topological structures. Researchers found these hidden patterns reach up to 48 dimensions, offering a vast new “alphabet” for encoding quantum information. Unlike previous assumptions, this topology can emerge from a single property of light—orbital angular momentum.
Apple explains why M5 chips have three different core types in new interview
Apple explains M5's three core types: super cores for single-thread tasks, performance cores for multi-threading, and efficiency cores.
Crimson Desert developers "doing our utmost" to respond to its various launch issues, as game still passes huge one-day sales milestone
Crimson Desert - the ambitious single player RPG spin-off from Pearl Abyss - has sold through 2m copies following its release.
After weeks of hype, Crimson Desert debuts to high player counts but "Mixed" Steam reviews, citing "disjointed graphics", lovable cats, "awful" UI and more
Pearl Abyss' single player RPG spin-off Crimson Desert released last night, and has had a rocky debut.
Latto Launches 'Big Mama' With New 'Business & Personal' Single
Latto is back with "Business & Personal," the first official single from her forthcoming 'Big Mama' album. Get all the details.
Scientists turn CO2 into fuel using breakthrough single-atom catalyst
Researchers have created a cutting-edge catalyst that turns CO2 into methanol more efficiently than ever before. Instead of using clumps of metal atoms, they engineered a system where each single indium atom actively drives the reaction. This dramatically reduces energy needs while making the process easier to study and optimize. The result could accelerate the shift toward cleaner fuels and sustainable chemical production.
Hermès Now Sells $1,250+ MagSafe Chargers Wrapped in Calfskin Leather
Luxury brand Hermès has a new series of MagSafe-compatible chargers for the iPhone and Apple Watch, with prices that are higher than the cost of an iPhone 17 Pro Max. The $1,250 Paddock Solo Charger is a magnetic charger that works with a single device, while the $1,750 Paddock Duo can charge an Apple Watch and iPhone at the same time. The $1,750 Paddock Yoyo is also a dual charger, but it has a USB-C cable that wraps around the charger for travel purposes.
Pittsburgh premiere of 'Eureka Day' stage comedy tackles vaccine politics
Jonathan Spector’s play “Eureka Day,” making its Pittsburgh premiere at City Theatre, depicts what happens to even a group of people who might seem highly compatible when a single hot issue scorches the earth between them.
Khan says Labour should rejoin EU customs union and single market this parliament
London mayor also says his party should make clear manifesto commitment on full membership in next parliament
Crisis or opportunity? Thousands of baby boomer business owners to retire in West Michigan
Roughly ten thousand baby boomers, every single day in the United States, retire from the workforce.
Exclusive: $599 MacBook Neo easily beats $1,119 Dell laptop on Windows 11 benchmarks - yes, macOS may well be the best platform ever for Microsoft's OS
Despite running a mobile CPU and Windows in a virtual machine, the MacBook laptop excelled in single-core CPU performance
Family Sharing in iOS 26.4 No Longer Forces Adults to Share a Payment Method
With iOS 26.4, Apple has made a small but useful change to the way that Family Sharing works. Each adult member of the family can now use their own payment method for purchases, rather than being forced to share a payment method. Apple has long required all of the members of a Family Sharing group to use a single shared payment method for app and content purchases when purchase sharing is turned on, with no option for family members to use separate payment methods.
As Trump administration cracks down on health care fraud, people with disabilities feel singled out
As the Trump administration goes after fraud in health care, advocates say the disability community feels singled out.
EU Inc. – making business easier in the European Union
The Commission presented EU Inc., a new single set of corporate rules that will be the same and apply across the EU.
EU Inc proposal seeks to rival US in innovation by easing startup creation
The European Commission proposed on Wednesday allowing firms to set up in as little as 48 hours and operate according to a single set of rules across the 27-nation EU in a bid to narrow the gap with the United States in innovative startups.
Philip Morris International U.S. to Launch New Business Solutions Center, Creating 180 Jobs in Tampa Bay Area
Today, Philip Morris International's U.S. businesses ("PMI U.S.") announced an investment of approximately $50 million in a new Business Solutions Center in Tampa, Florida. The Center will create approximately 180 direct and indirect high-skilled jobs and represents a pivotal expansion of PMI U.S. operations, consolidating key functions—business solutions, distribution operations, and customer service—into a single hub. This investment is designed to enhance operational efficiency across these f
NVIDIA launches RTX PRO 4500 Blackwell Server Edition, single-slot GPU with 32GB memory and 165W TDP
RTX PRO 4500 Blackwell Server Edition is a slimmer, passively cooled workstation card NVIDIA has just announced the RTX PRO 4500 Blackwell Server Edition,
Ronda Rousey's return likely a one-and-done deal
Former UFC women's bantamweight champion Ronda Rousey will return to competition after a decade on May 16, at the Intuit Dome in Inglewood, California. "Rowdy" will face fellow women's MMA pioneer Gina Carano under Most Valuable Promotions. Rousey, 39, last fought in December ...
FIU defeats UTEP softball in DH to sweep series
MIAMI, Florida – UTEP softball finally saw action late Friday night after multiple weather-related schedule changes but ultimately fell to FIU, 4-3, in the series opener. Originally scheduled as part of a three-game series across three days, the weekend slate was first moved to an early Friday doubleheader and Saturday single game before prolonged lightning delays pushed the matchup to […]
Battle of the Badges Hockey Championship raises $285K for Dartmouth Health Children's
This year, the event raised $285,000, the largest single-day total in the event's 18-year history.
Scientists just discovered a tiny signal that volcanoes send before they erupt
A new detection method called “Jerk” could dramatically improve how scientists forecast volcanic eruptions. By using a single broadband seismometer, the system can detect extremely subtle ground movements caused by magma pushing underground—often hours before an eruption begins. Tested for more than a decade at the Piton de la Fournaise volcano on La Réunion, the tool successfully predicted 92% of eruptions between 2014 and 2023, sometimes giving up to eight hours of warning.
2K flights canceled in single day, turning major airport into virtual ghost town
Winter blizzards slam Upper Midwest, forcing airlines to cancel nearly 2,000 flights Sunday. Chicago O'Hare and Minneapolis airports hit hardest.
Who will be Eastern Michigan's next basketball coach? Five names to watch
Eastern Michigan parted ways with head coach Stan Heath on Sunday, at the end of his five-year contract. He didn't have a single winning season.
Broncos Country underwhelmed by Broncos free agency moves
Based on results of our FanDuel SB Nation Reacts survey earlier this week, it is pretty clear what Denver fans think of the team signing ONLY Broncos free agents. Not thrilled. At the time of the survey, the Broncos had re-signed Alex Palczewski, Adam Trautman, Alex Singleton, Nate Adkins, and Justin Strnad. Since then, they […]
Every Single Cell in the Universe Is Conscious, Research Suggests
This could reshape everything we know about cognition.
Bam Adebayo makes NBA history, delivers 2nd-best single-game point total of all time, top fantasy High Score of season
Prep sports roundup: Harvard-Westlake pulls out 5-4 baseball win over Sierra Canyon
Ira Rootman delivers two-run single in the seventh to rally Harvard-Westlake in Mission League opener.
US is 'on top' of possible Iran sleeper cells, Trump says. What are they?
Asked about domestic Iran-aligned sleeper cells, Trump said the United States is "watching every single one of them." What to know.
Single protein could dramatically alter trajectory of Alzheimer's disease
In people destined to get Alzheimer's in their mid-40s, one protein can delay the onset of the disease by about 20 years.
Housing proposal threatens build-to-rent business model
A bipartisan housing proposal in the U.S. Senate could reshape the rapidly growing single-family rental market by forcing large institutional investors to sell newly built rental homes within seven years, The Wall Street Journal writes. Supporters say the measure would help expand homeownership by preventing deep-pocketed investors from holding large inventories of houses that might […]
Galaxy S26 Ultra for $399 Seems Good
Every single year, we try to stress that if you are interested in Samsung’s latest devices, the best time to strike is during the pre-order period. That time is coming to... #GalaxyS26Ultra #Samsung
Statewide single-payer health care is back on the table, with a promise of no tax increase for 91% of Ohioans
Senate Bill 78 would not eliminate private insurance, as those providers would still be able to offer non-duplicative supplemental coverage.
What crocodile bones teach us about dinosaurs
Paleontologists have often determined how old a dinosaur was by counting the growth rings in its bones. Just like with trees, it was thought that each ring corresponded to a single year of age. But researchers who studied crocodiles at an outdoor recreation center near Cape Town appear to have poked a hole in that approach. In the crocodiles, which are some of the closest living relatives of dinosaurs, there was more than one growth ring laid down per year. The results contribute to a growing debate over the best way to age animals.Read more of freelance science reporter Ari Daniel’s story here.Interested in more on the future of science? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.
Broncos 'biggest need' revolves around Alex Singleton, Dre Greenlaw uncertainty
This is a sneaky big need for the Broncos this offseason.
IREN’s $6 Billion Stock Offering: Is This AMC Entertainment 2.0 for the AI Era?
Bitcoin miner-turned-AI cloud operator IREN (NASDAQ:IREN) shocked investors this week with a stunning announcement: it expanded its at-the-market (ATM) equity offering program to a whopping $6 billion — roughly half its current market capitalization. The news sent shares tumbling 8.5% in a single session as dilution fears gripped the market. While the dilution won’t hit ... IREN’s $6 Billion Stock Offering: Is This AMC Entertainment 2.0 for the AI Era?
Bloom and bust: can Sarah Raven regrow her garden business?
The plantswoman who single-handedly brought dahlias back into fashion and nurtured the UK through Covid had become a perennial in the horticultural firmament. Then it all went wrong
First MacBook Neo Benchmarks Are In: Here's How It Compares to the M1 MacBook Air
Benchmarks for the new MacBook Neo surfaced today, and unsurprisingly, CPU performance is almost identical to the iPhone 16 Pro. The MacBook Neo uses the same 6-core A18 Pro chip that was first introduced in the iPhone 16 Pro, but it has one fewer GPU core. The MacBook Neo earned a single-core score of 3461 and a multi-core score of 8668, along with a Metal score of 31286.
Electrons catapult across solar materials in just 18 femtoseconds
Electrons in solar materials can be launched across molecules almost as fast as nature allows, thanks to tiny atomic vibrations acting like a “molecular catapult.” In experiments lasting just 18 femtoseconds, researchers at the University of Cambridge observed electrons blasting across a boundary in a single burst, far faster than long-standing theories predicted. Instead of slow, random movement, the electron rides the natural vibrations of the molecule itself, challenging decades of design rules for solar materials.
OpenAI brings its Codex coding app to Windows
The software allows developers to task multiple AI agents to work on a single task.
Sony won't bring any more single-player PlayStation games to PC
Titles like Ghost of Yotei will remain exclusive to Sony's hardware.
A US Navy submarine sank an Iranian warship with a torpedo
Secretary of Defense Pete Hegseth called the sinking of an Iranian warship with a single Mk48 torpedo a "quiet death."
Towns take the temperature on support for universal health care
Several Vermont towns have voted on a measure urging the Legislature to reconsider single-payer health care.
For California Democrats, single-payer health care is back. Voters have heard it before
Candidates for governor are promising universal public health care, which might sound familiar to California voters who've heard it before.
Prep baseball: Harvard-Westlake gets walk-off win over Huntington Beach
Ethan Price delivers walk-off single in 4-3 win for Harvard-Westlake over Huntington Beach
First M4 iPad Air Benchmarks Surface
Ahead of the launch of new iPad Air models equipped with the M4 chip, preliminary Geekbench benchmark results have surfaced for the device, giving us an idea of how its performance compares to the prior-generation M3 iPad Air. A pair of benchmarks from the 13-inch M4 iPad Air with Wi-Fi + Cellular (iPad16,11) suggest the M4 iPad Air CPU is 17.3 percent faster in single-core performance and 7.9 percent faster in multi-core performance.
Apple's Studio Display XDR Supports DICOM Medical Imaging for Diagnostic Radiology
The new Studio Display XDR is designed for all kinds of professional work, and it is uniquely suited for use in the medical field. The Studio Display XDR supports DICOM medical imaging presets and a Medical Imaging Calibrator so it can be used for diagnostic radiology. Radiologists will be able to view images right on the Studio Display XDR without the need to use a single-purpose medical imaging display.
Hybrid Solar Panel Turns Raindrops into Electricity
A Spanish research team’s patented thin film generates 110 volts from a single raindrop’s impact.
The devastating condition that looks like a heart attack — and 90% of patients have a single trait in common
Research in college and NFL athletes links early sports specialization to higher injury rates
New research presented at the 2026 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) studied college and National Football League (NFL) players to determine the long-term impact of early, single-sport specialization on injury risk. The studies showed that repetitive stress from focusing on one sport from a young age can have negative, lasting effects on the musculoskeletal system, potentially making them more prone to hip dysfunction, reduced function, and surgical interventi
UCLA Health Receives $100M for Mental Health Treatment
UCLA Health has received the largest single gift in its history devoted to mental health care: $100 million to expand mental and behavioral health services at the health campus, in part by supporting construction of a new neuropsychiatric hospital.
Buffettology Without Buffett in Abel’s First Shareholder Letter
Greg Abel has passed his first test since taking over from Warren Buffett as Berkshire Hathaway Inc.’s new chief executive officer. In his introductory shareholder letter, he emphasizes that Berkshire’s culture runs far deeper than a single man. Yet, almost in the same breath, he tells us not to worry — after all, Buffett is still lurking around the office.
Scientists Uncover the Secret Structure Behind “Nature’s Proton Highway”
By freezing a crucial phosphoric acid complex to near absolute zero, scientists uncovered a single, unexpectedly stable structure at the heart of proton transport.
BigXthaPlug And 600 Entertainment Make Noise For Texas With “6WA”
The Dallas rapper and his crew represent their home state and salute the West Coast on the first single from their upcoming mixtape of the same name
BigXthaPlug and 600 Entertainment Make Noise for Texas With ‘6WA’
The Dallas rapper and his crew represent their home state and salute the West Coast on the first single from their upcoming mixtape of the same name
BigXthaPlug and 600 Entertainment Rep Texas With '6WA'
BigXthaPlug and his 600 Entertainment crew are representing Texas and saluting West Coast legends with their new mixtape and single
Colorado single-payer study lacks transparency
Coloradans have a right to expect transparency, accountability and fiscal responsibility from public institutions. Unfortunately, the ongoing single-payer health care study commissioned last year under SB25-45 is raising more questions than answers. Despite repeated warnings from voters and prior analyses, the Colorado School of Public Health is moving forward with a new single-payer study that […]
UCLA Health announces $100 million gift from Stewart and Lynda Resnick to advance mental health care
UCLA Health has received the single largest gift to advance mental health care in its history – $100 million from global philanthropists Stewart and Lynda Resnick, co-owners of Los Angeles-based The Wonderful Company, one of the nation’s largest privately held companies.
NCAA committee recommends stiff penalties for college football teams that try to circumvent transfer portal
This is the first year of a single transfer portal window in college football
Melvin Robert Shines in KTLA Spotlight as Morning News Entertainment Anchor
Ever since Melvin Robert joined KTLA’s “Morning Show,” he has lit up the show with an incandescent smile and effervescent charm as he delivers entertainment hot topics. The Inglewood native replaced Sam Rubin last year when the iconic news personality suddenly died.
Rubio Was Looking at His Phone After Trump Praised Him in State of the Union Speech
Shortly after Secretary of State Marco Rubio was singled out for praise, a New York Times photographer captured him reading messages from Mr. Trump’s special envoy to Venezuela.
Scientists finally solve the mystery of the horse whinny
Horses have a vocal trick no one fully understood until now. Scientists have discovered that when a horse whinnies, it produces two completely different sounds at the same time. One is a deep tone created by vibrating the vocal folds, similar to how humans sing. The other is a high-pitched whistle generated inside the larynx, something never before confirmed in a large mammal. This rare ability, known as biphonation, likely helps horses send multiple emotional signals in a single call.
Democrats Counter Trump With Their Own Version of a Wall Street Landlords Ban
As the president prepares to deliver a State of the Union address likely to touch on his own plan, Senate Democrats introduced a bill with their own vision for limiting investors’ purchases of single-family homes.
What to Expect From the iPhone 17e Launching in March 2026
We've got just over a week to go until Apple's "Special Experience" on March 4, and we're expecting to see the iPhone 17e announced during the week of the event. The iPhone 17e will be the first update to the new low-cost iPhone 16e that Apple unveiled in February 2025. Design The iPhone 17e will look a lot like the iPhone 16e, featuring the same 6.1-inch display size, single-lens rear camera, and black and white color options.
POKÉMON Gave Every Single Pokémon Their Own Logo to Celebrate 30 Years
Celebrating 30 years, The Pokemon Company gave every single Pokemon their own individual logo. Take a look at the 1000+ designs!
Former WNBA two-time champion Kara Braxton died in a car accident
Braxton was in a single car crash outside of Atlanta. Here's what we know about how the 43-year-old mother of two died.
Tyrese Haliburton dealing with 'very painful' shingles diagnosis as Pacers season takes another strange twist
Indiana's already-sidelined superstar will be away from the team as he recovers
Tencent Studio Closes In 5 Years Without Releasing A Single Game
TiMi Montreal studio has quietly closed less than five years after getting announced
Olympics news, live updates: U.S. now has its most gold medals in a single Winter Games, will look to add USA hockey gold on Sunday
Follow along with Yahoo Sports for all the news, events and medals from the Milan Cortina Olympics.
Ilia Malinin skates with message, 'Is this what you wanted?' at Olympics gala
Ilia Malinin took the ice for the first time since his disastrous men's singles free skate and send a message of hurt and redemption.
Healthy Yordan a threat to Bagwell's HR mark -- and key to playoff return
WEST PALM BEACH, Fla. -- The Astros’ single-season home run record of 47 was set by Hall of Fame first baseman Jeff Bagwell 26 years ago -- the first year Houston moved into its downtown ballpark. Lance Berkman made a run at Bagwell’s record six years later, but he finished
Olympics news, live updates: U.S. takes first in mixed aerials, now has its most gold medals in a single Winter Games; Jordan Stolz, women's curling on tap
Samsung Galaxy S26 Ultra Beats The Apple iPhone 17 Pro Max In The Latest Geekbench 6 Tests
Samsung Galaxy S26 Ultra smokes the Apple iPhone 17 Pro Max in single-core and multi-core Geekbench 6 tests.
CFO whose business fell 10% from tariffs cheers Supreme Court ruling: ‘No single person should have unilateral authority over tariffs’
Matt Totsch, the CFO of manufacturer Trim-Tex, said businesses like his have been dealing with crippling uncertainty caused by Trump’s chaotic tariff policies.
5 Crucial Steps To Growing Your Business With A Newsletter
Your newsletter could be your single biggest growth channel. These 5 steps from a founder who's built 10M+ subscribers show you exactly how to make it work.
Alysa Liu not only won gold — she did it on her terms
Liu became the first American woman to win gold in singles figure skating in more than two decades, capping a personal comeback that began when she walked away from the sport as a teen.
AMD Ryzen 10000 "Olympic Ridge" to Debut with 6/8/10/12/16/20/24-Core "Zen 6" SKUs
AMD's next-generation desktop Ryzen 10000 series "Olympic Ridge" processor platform will supposedly come in various SKU flavors ranging from 6 to 24 cores, in some very specific configurations based on the CCD structure. The first in the lineup are single-CCD SKUs, which include 6, 8, 10, and 12 "Ze...
AMD’s Zen 6-Powered Ryzen “Olympic Ridge” Desktop CPUs To Come In 24, 20, 16, 12, 10, 8 & 6 Core Configs
AMD will roll out its next-gen Olympic Ridge Ryzen "Zen 6" Desktop CPUs with up to 24 cores in dual & 12 cores in single CCD configurations.
Microsoft Unveils Glass Storage System Lasting 10,000 Years
Project Silica uses femtosecond lasers to encode data into borosilicate glass, storing 4.8 terabytes--roughly two million books--on a single coaster-sized plate.
iPhone 17 Pro Max Curiously Becomes Most Traded-In Smartphone
New trade-in data indicates that Apple's iPhone 17 Pro Max has rapidly become the single most traded-in smartphone. According to a new report from SellCell, Apple's latest flagship iPhone has quickly risen to the top of the independent trade-in market, accounting for 11.5% of all devices appearing in the top-20 trade-in rankings just months after release. The analysis is based on SellCell internal trade-in data and secondary market pricing trends gathered from 40 independent iPhone buyers.
Five Berkeley Lab Scientists Receive DOE Early Career Research Awards
Five scientists from Lawrence Berkeley National Laboratory (Berkeley Lab) have received Early Career Research Program (ECRP) awards from the Department of Energy. The ECRP program, now in its 16th year, was established to bolster the nation’s scientific workforce by supporting exceptional researchers at the outset of their careers, when many scientists do their most formative work. Recipients use the funding to pursue projects that have the potential to solve scientific challenges and advance the country’s STEM capabilities. To be eligible for the program, a researcher must be an untenured, tenure-track assistant or associate professor at a U.S. academic institution, or a full-time employee at a DOE national laboratory or Office of Science user facility, who is within 10 years of having earned their doctorate. Awards to an institution of higher education will be approximately $875,000 over five years, and awards to a DOE national laboratory or Office of Science user facility will be approximately $2,750,000 over five years. This year’s Berkeley Lab awardees and their projects are listed below: Timon Heim: Better detectors for more powerful particle colliders Timon Heim is a staff scientist in the Physics Division. His ECRP project will develop a new type of detector that can track the particles generated by collisions in particle colliders with high spatial and temporal resolution. Current detectors in use at high-energy colliders, like the ATLAS detector at the Large Hadron Collider (LHC) at CERN, can track the trajectory and measure momentum of particles, but they can’t track a particle’s time of arrival with sufficient precision to discern from which of the many particle interactions they originate. Heim’s proposed technology — called a 4D tracking detector, because it captures data about particles’ positions in space and time — aims to solve this challenge, allowing researchers to glean more precise data from collision experiments to uncover new insights into fundamental forces and potentially discover new particles. The enhanced capabilities of 4D detectors will be a necessity for experiments at future colliders, such as the Muon Collider or Future Circular Collider. The project will develop custom microelectronics that process the signal of a pixelated silicon sensor that can register charged particles passing through it in an extreme radiation environment that these colliders produce during operation. The goal is to measure individual particles’ position with 50-micro-meter spatial and 50 pico-second (one trillionth of a second) temporal precision, for an incoming flux of around 1 billion particles per second per square centimeter. Harrison Lisabeth: Studying underground processes to unleash abundant energy Harrison Lisabeth is a research scientist in the Energy Geoscience Division focused on combining real-world experiments and AI to guide development of geothermal energy systems. His project will explore how deep underground rock formations – where geothermal wells are dug – are stressed by chemical reactions of the minerals and mechanical strain from movements in the Earth. A better understanding of subsurface stresses is essential to engineer safe and reliable geothermal wells that access the heat of deep rocks to produce electricity. It is estimated that the U.S. could generate ten times the amount of energy needed to power the grid using geothermal sources. Lisabeth plans to simulate how minerals grow, dissolve, and influence the behavior of surrounding rock in geothermal reservoirs by tracking chemical changes in rock samples under pressure in the lab. The project will also develop machine learning models to predict geologic strain based on field measurements and refine existing models that describe how common rock types deform under stress. Combining these approaches, Lisabeth hopes to develop a framework to predict stress to improve stability and longevity of geothermal wells. Daniel Carney: Pushing the quantum boundaries of particle measurement Daniel Carney is a staff scientist in the Physics Division who uses quantum information science to study particle physics and gravity. At very small scales, “quantum noise” — random fluctuations from the act of measurement — can drown out faint signals from rare processes. Carney’s ECRP project, “Fundamental Physics at the Quantum Limits of Measurement,” aims to build a new mechanical quantum sensor that can measure extremely small particle interactions below the limits of that quantum noise. The approach uses lasers to hold a tiny bead containing radioactive atoms; when one decays, the system measures the bead’s motion and the energy of any particles emitted. The experiment’s initial goal is to search for heavy sterile neutrinos, hypothetical particles predicted by some extensions of the Standard Model. The system could also help measure the mass of the neutrino, study the way particles interact through the electromagnetic and weak forces, and hunt for low-mass dark matter — all unsolved mysteries in particle physics. Callum Wilkinson: Using machine learning to demystify neutrinos Callum Wilkinson is a staff scientist in the Physics Division and part of the international Deep Underground Neutrino Experiment (DUNE) hosted by Fermi National Accelerator Laboratory. DUNE will create an intense beam of neutrinos that interact in detectors in Illinois and, after an 800-mile journey through the earth, in massive detectors in South Dakota. By precisely measuring neutrinos and how they change, researchers will get a better understanding of their fundamental properties and whether they are responsible for why there is so much more matter than antimatter in our universe. Wilkinson’s ECRP project will apply two machine learning techniques to improve the analysis of DUNE’s data and enhance the experiment’s precision. One approach will look for hidden patterns in how neutrinos interact and produce low-energy particles, while the other will help correct for distortions in what the detectors record. The methods will be tested on one of DUNE’s prototype detectors and could be used in other neutrino experiments, improving their measurements and helping scientists build better models. Aditi Krishnapriyan: Machine learning methods that scale as datasets grow Aditi Krishnapriyan is a faculty scientist in Berkeley Lab’s Applied Mathematics and Computational Research Division (AMCR) and assistant professor at UC Berkeley. Her project, awarded through UC Berkeley, will develop machine learning methods that scale with dataset size for modeling complex, multi-scale phenomena. The resulting tools can be applied in a wide range of research, including the study of new electrolytes for batteries or the examination of molecular interactions. ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.