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Scientists Say a Critical Ocean Current System May Already Be Past the Point of No Return

Scientists have long debated whether the AMOC is nearing collapse, but the latest findings are certainly alarming.

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Jul 9 • 1:30 PM EDT • Science • gizmodo.com
Connecticut reports 23 cases of cyclosporiasis as health officials urge produce washing

Connecticut health officials are urging people to thoroughly wash fresh produce after the state reported 23 cases of cyclosporiasis as of July 1. The parasitic illness spreads through eating contaminated food, according to doctors. The Connecticut Department of Public Health said it has not been able to determine whether the cases are concentrated in one area and is working to…

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Jul 8 • 9:43 PM EDT • Health • nbcconnecticut.com
Platner leave Democrats with egg on their faces

Democrats have a number of Graham Platner-related problems as they await his decision on whether to drop out of the Maine Senate race amid a rape allegation he denies.

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Jul 8 • 7:33 PM EDT • Politics • cnn.com
FDA releases report on toxic metals in tampons and potential health risks

Previous research had raised safety worries over whether metals such as arsenic and lead in menstrual products could pose health risks.

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Jul 8 • 3:37 PM EDT • Health • nbcnews.com
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Greenland is being swarmed by autonomous drones and underwater robots as scientists race to answer one question: How close is Earth to a climate tipping point?

Self-driving drones, robotic boats, and underwater vessels will be sent to Greenland to find the answer to one of the most important questions in the realm of climate science: how far are we from crossing the climate tipping point on our planet? In this expedition, scientists hope to collect data from some of the world's most difficult glaciers, improve sea-level projections and assess whether major ocean circulation systems are changing irreversibly.

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Jul 8 • 11:15 AM EDT • Science • timesofindia.indiatimes.com
‘SOULM8TE’ director talks ‘M3GAN’ spinoff’s return as digital release (exclusive)

‘SOULM8TE’ director Kate Dolan talks about the ‘M3GAN’ spinoff’s return as a digital release. ‘There’s such an audience for this movie, whether it be at home or in the theater.’

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Jul 8 • 9:00 AM EDT • Entertainment • ew.com
“M3GAN” spinoff “SOULM8TE” boots back up: Director talks erotic thriller’s new life as a digital release (exclusive)

“There’s such an audience for this movie, whether it be at home or in the theater,” Kate Dolan tells EW.

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Jul 8 • 9:00 AM EDT • Entertainment • yahoo.com
You can complete medieval vampire RPG The Blood of Dawnwalker even quicker than previously thought - before even the prologue ends

The limiting factor will be whether you're good enough to do it, and most of you - most of us - will not be.

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Jul 8 • 8:32 AM EDT • Technology • eurogamer.net
Hungary moves to overhaul university models banned from Horizon Europe

Hungary’s new government is aiming to overhaul the governance model of the institutions and universities that lost access to Horizon Europe and Erasmus+ funds “in a short timeframe,” according to Péter Horváth, the new state secretary for science policy and innovation. “As of today, the two non-university foundation-controlled institutions under my remit have been transformed,” he told Science|Business. “We hope the universities will follow and that this will be enough to satisfy the EU’s demands.”Under the previous government, led by Viktor Orbán and his Fidesz party, many academic and scientific institutions were restructured and made into special public trust foundations, with members strongly linked to the government given lifelong mandates and significant decision-making powers with little oversight. The European Commission deemed that this undermined academic freedom and transparency in the country, leading to a ban on 34 institutions in 2022, including 21 universities, which saw academics in Hungary lose access to Horizon Europe grants. The new Hungarian government, elected in May and led by Péter Magyar and his Tisza Party, has promised to dismantle this governance model and restore the institutions to EU programmes. As a result, the European Commission has promised to return access to the Erasmus+ education mobility programme, but so far no concrete agreement has been made on the Horizon Europe programme for research and innovation. Hungary has already made legislative changes in June to allow the institutions to be reformed and set a timeline for the implementation.The non-university foundations, which are mainly cultural centres such as the Foundation for Hungarian Culture or the Makovecz Campus Foundation, will all be dissolved by August 31 this year, a date tied to EU-set milestones that Hungary must meet to unlock frozen funds, with control transferred to relevant ministries. Meanwhile, the universities will have until 31 August 2027. For each university foundation, the government will set the dissolution date and the body to take over operations. There is no final decision on a permanent new model for the universities, according to Hungarian MEP Eszter Lakos, who is shadow rapporteur for the Horizon Europe specific programme, a separate piece of legislation detailing implementation rules for the EU’s next research programme, due to start in 2028. “The aim of the transition year is to settle this with [the universities], not to impose a model, and not to put them under state control,” she told Science|Business. “The goal is to give academic independence back to universities.”There are three models that are most likely to be implemented. One would be a return to a traditional, state-run model. Another could be a newer, more self-standing public institution. A third option would be a reformed version of the foundation models that meet EU standards. According to Lakos, the dismantling of the system put in place by the Orbán government is well underway and if all goes according to plan, Hungary could regain access to EU research money by the start of the next academic year in 2027. “I believe that the Hungarian government is doing the necessary changes so the universities could return as beneficiaries to Horizon from the next school year,” she said. In the meantime, “the universities, institutes and cultural assets carry on under proper public stewardship rather than a handful of unaccountable trustees,” said Lakos. The laws passed in June impose new safeguards: board terms are capped at four years and renewable only once, appointments are made through open competitions and sitting politicians cannot join joining these boards.It remains unclear whether a domestic science funding programme set up as a back-up scheme by the former government following the EU funding ban, called HU-rizon, could be continued. “This programme should never have had to have been established in the first place, but it has proven to be quite popular,” he said. “I am considering continuing this programme with a refined focus on helping international collaborations.”Re-organising the research network One of the first priorities for Horváth and his cabinet is to resolve questions over the future of the Hungarian Research Network, Hun-Ren. The network of academic institutes was taken away from the Hungarian Academy of Sciences in 2019 and turned into a quasi-private organisation, with similarities in its governance to the public trust foundations.Horváth and his team have consulted over 5,000 representatives from the network and the conclusion is broad unhappiness with the directors of all the institutes involved. “We have presented the results to the president and the chief executive of the network and this is currently being discussed,” Horváth said. The plan is to re-integrate the network back into the Academy of Sciences but in an improved way, “learning from mistakes of the past,” he added. The government also wants to reintegrate four humanities and social science research centres into the network that the previous government had transferred to Eötvös Loránd University. The transfer brought sharp criticism from the academic community, with a group of Hungarian research heads, including European Research Council grant recipients, sending an open letter to Orbán warning that the transfer would “cause historically significant harm to the entirety of Hungarian scientific life.” The transfer was “one of the biggest shames in Hungarian research in the past 20 years,” Horváth said. “We want to immediately re-integrate them back into the research network and to regain the trust of these institutions, because the way they were treated was really unfair.”Another pressing issue is the Élvonal Excellence Research and Talent Development Foundation, led by Nobel laureate Ferenc Krausz. The foundation signed a financing agreement with the former government earlier this year for a budget of over €730 million over the next five years. The goal is to create a world-class centre to attract top talent from abroad and to develop local researchers. But there was little transparency about this foundation, and news of its huge budget, which is nearly as much as Hungary’s entire research budget, caused a stir in the media following the recent elections. Another issue is that, as with the foundation boards of the institutes banned from Horizon Europe, there was little-to-no oversight of decisions led by Krausz. “It was an excellent idea but an unacceptable execution,” Horváth said of the foundation. “The fact that this is out of the Hungarian funding scheme, mostly concentrating on one person who decides on the budget is unacceptable for us.”The government plans to merge the centre with the National Research, Development and Innovation Office, the country’s R&D funding agency, with a reduced budget. Horváth is hopeful that Krausz will still be involved. The new government’s R&D goalsA phrase that crops up regularly during the discussion with Horváth is “democratic process.” The new state secretary is determined to involve Hungary’s research community in shaping future policies. This marks a departure from the previous government’s approach, and several people in Hungary’s research community have commented on the openness of the new government. In terms of concrete goals, Horváth and his team already have plans. He wants to create a new science fund in Hungary, based on the best practices of other European countries. The fund would not be tied to annual government budgets and would provide long-term, stable financing. “If we were to succeed in creating this fund, then I think it would be one of the biggest achievements for me in this period of government,” Horváth said. On the innovation side, he is looking into how best to bring in the private sector. “We want to make sure that we are working with the private sector to support innovation,” Horváth said. One of his big aims is to introduce entrepreneurship teaching into high schools. Hungary already has a reputable national academy offering research and innovation training in the field of natural sciences, and Horváth wants to expand this to all disciplines and across the whole country. “One of the main ways to elevate our innovative businesses is to teach our children to be innovative,” he said. “This will probably need ten years to pay off, but this is what we should do. Our aim is to make Hungary strong in our region, and this is what is needed.” Related articlesHungary’s Horizon Europe performance in numbersCommission unlocks Erasmus+ cash for Hungary, Horizon could be next‘Academic Huxit.’ Hungarian researchers speak out on impact of EU ban A more difficult task will be funding. The new government is aiming to increase research spending to 2% of the GDP by 2030, and then increase it to 3% in line with EU objectives. Currently, spending sits around 1.3%. But according to Horváth, the current budget, inherited from the previous government, is “heavily in the negative,” so any plans to increase research spending will have to start next year. Achieving 2% by 2030 already needs a big push, almost doubling the research budget. “This is something we’d definitely like to reach, and something I can see us achieving,” he said. “From the 2030s, I’d like to see an innovative generation growing up that can help us reach the 3% target.” Positivity in the new governmentDespite the many challenges facing Horváth and his team, the mood is positive. “It feels a bit like a start-up right now. Everyone is working 24/7, day and night, trying to do as much as they can. There is a lot of energy,” he said. It is a big change for the state secretary who, like many in his cabinet, is coming from a background in research or business, and not in politics. “Six weeks ago, I was sitting with my microscope and my research PhDs, so it’s been a big change for me,” said the computer scientist, who was previously the director of the Institute of Biochemistry at the Hun-Ren Biological Research Centre in Hungary and worked at the Institute for AI for Health at Helmholtz Munich. But he is relishing the task to transform the country’s R&D landscape. “We feel enormous support from the Hungarian people, but also from Europe,” he said. “We’ve received a lot of letters of support from around Europe. There is big trust there, and huge responsibility on our side. We want to get everything back on track, and there’s a lot to do.”

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Jul 8 • 5:47 AM EDT • Science • sciencebusiness.net
Health risk fears for storks in Europe over ‘junk food’ from landfill

Rubbish dumps can expose birds to contaminants, raising questions over whether landfill foraging helps or harms

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Jul 8 • 3:30 AM EDT • Health • theguardian.com
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McConnell speaks to Republican leaders as speculation swirls about his health

Aides have declined to release any information about McConnell's condition, fueling speculation about his prognosis and whether he will be healthy enough to be at the Capitol next week.

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Jul 7 • 7:47 PM EDT • Health • latimes.com
Explaining The Comcast and NBCUniversal Divorce

(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) I hope everyone had a happy Fourth of July in America, celebrating the country’s 250th birthday. Frankly, I am bummed the 250th wasn’t a bigger celebration, but that’s a different topic for a different Substack. While it was generally a quiet week on the entertainment/streaming/media business fronts, we still had some interesting news stories. Actually, that kinda undersells one of the stories, a huge, huge, huge divestment that could upend the entertainment landscape... So let’s get right to it. In today’s column, I’ll cover Comcast spinning off the rest of NBCUniversal, an entertainment company investing in an LLM company and an LLM-owner investing in a movie studio, the latest round of threats of digital tariffs, and more. Let’s dive in. Subscribe Most Important Story of the Week - Most: Comcast/NBCU Breakup!!!! If I had to describe my reaction to Comcast spinning out NBCUniversal, it feels like a relationship ending, either breaking up or divorcing. Comcast’s decision to spin off the rest of NBCUniversal, after spinning off some of its cable assets into Versant last year, really does feel like a family breaking up under “irreconcilable differences”. Of my stereotypes of the entertainment moguls, my go-to for Comcast CEO Brian Roberts—heir to the Comcast fortune, but a man who’s been at the helm for 24 years now, and president for twelve years before that—is that he likes building empires. He cut his teeth acquiring cable rivals in the 1990s and tried to buy Disney repeatedly, then settled for NBCUniversal after a long court battle. (Contrast this with Rupert Murdoch, a man who also loved to buy, but would also sell when the price is right. Murdoch made Fox out of nothing, but then sold 20th Century Fox to Disney, arguably at the top of the market. So I understood why he sold.) But I don’t understand Roberts’ motivation to sell now. I have some explanations but no single, super-satisfying explanation. Strategically, it would just make more sense to have kept NBCUniversal in-house, especially for a one-time empire builder like Comcast. Yet one powerful force—arguably the decider in modern capitalism—likely overwhelmed all other considerations. At first, I thought I’d arrange my thoughts as a “Five Why” analysis, digging through each layer of the puzzle. But instead, I found myself asking, “But…why?” (And I only ended up with four sections.) So let’s look at Comcast from that angle. Then, at the end, I’ll give my biggest strategic recommendation for every company in Hollywood. It’s obvious, but sometimes, the obvious strategy is the most ignored. But…Why? The Stock Market, Conglomerations, and Sum of the Parts Analysis We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… Why Comcast could never get a “tech company” valuation The not-so-secret motivation for Comcast What Versant has to do with all of this The key strategic advice I think every entertainment exec should follow (though it’s really obvious) Some big AI investment news… Whether we’ll see digital tariffs… And more… ...please subscribe! We can only keep doing this great work with your support.

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Jul 7 • 3:53 PM EDT • Entertainment • entertainment.substack.com
Maine Democrats jockey to replace Graham Platner as he faces pressure to drop out

As of Tuesday morning, Platner remained undecided about whether to drop out of the race and wants to see a replacement nominee who shares his vision, according to a source.

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Jul 7 • 3:40 PM EDT • Politics • nbcnews.com
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McConnell spoke to GOP leaders amid uncertainty about his Senate return

Sen. Mitch McConnell (R-Ky.), who has been hospitalized since June 14, spoke to Senate Republican leaders on Monday and Tuesday amid growing speculation about whether he will return to the Senate b…

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Jul 7 • 2:45 PM EDT • Health • thehill.com
Opinion | How Socialism Emerged in American Politics

The debate has shifted from whether the government should redistribute wealth to how much redistribution is enough.

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Jul 7 • 1:58 PM EDT • Politics • wsj.com
Scientists discover how astrocytes help memories last

Some memories remain with us for years, shaping how we learn from experience and adapt to the world around us. Others disappear quickly, even when they once seemed important. Although scientists have long studied how memories are formed in the brain, far less is known about what allows certain memories to persist over time. A research team led by Dr. KOH Wuhyun at the Center for Memory and Glioscience within the Institute for Basic Science (IBS), together with researchers at the Korea Brain Research Institute (KBRI), has now discovered that astrocytes play a critical role in this process. Astrocytes are star-shaped cells in the brain that have traditionally been considered support cells for neurons. The study shows that these cells actively help determine whether memories can be maintained over long periods of time, revealing a previously unknown mechanism that supports long-term memory persistence.

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Jul 7 • 8:00 AM EDT • Science • eurekalert.org
Marine Le Pen verdict live: France's far-right leader awaits appeal ruling with presidential race at stake

Marine Le Pen will learn from a Paris appeals court whether an electoral ban for illicit party financing will prevent her running in next year's presidential election.

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Jul 7 • 6:33 AM EDT • Politics • reuters.com
McConnell’s health emergency sparks questions on whether he will return to Senate

Emergency dispatch audio indicating that someone at Sen. Mitch McConnell’s (R-Ky.) home in Washington, D.C., suffered “cardiac arrest” earlier this month has raised questions about when the former …

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Jul 7 • 6:00 AM EDT • Health • thehill.com
A Long-Awaited Verdict for Marine Le Pen Could Reshape France’s Politics

A court will decide on Tuesday whether to uphold Ms. Le Pen’s embezzlement conviction. If it does, the far-right leader will probably be barred from running for the presidency next year.

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Jul 7 • 12:01 AM EDT • Politics • nytimes.com
Details scarce as Mitch McConnell ‘continues recovery’ in hospital

Staff decline to give updates on senator’s health and whether he will be at Capitol when Senate returns

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Jul 6 • 9:09 PM EDT • Health • theguardian.com
Guest column: Louisiana’s broadband strategy is helping businesses compete

Every Louisiana business depends on reliable internet service, whether it is processing payments, managing inventory, communicating with customers or supporting employees. Broadband access now directly affects productivity, customer service, operating costs and the ability to compete in an increasingly digital economy. For years, many Louisiana communities dealt with limited internet options, inconsistent service and high […]

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Jul 6 • 3:50 PM EDT • Business • businessreport.com
How healthy is your brain? We now know how to find out

In our efforts to keep our brains healthy, how do we know what is working? Helen Thomson explores a new generation of tests that can reveal whether our efforts are paying off

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Jul 6 • 11:00 AM EDT • Health • newscientist.com
Business Monday: Big Island companies continue to recover from Kona low storms and earthquake

With the completion of property damage assessments from South Kona’s magnitude 6 earthquake that struck on May 22, Hawai‘i County officials now are waiting for Gov. Josh Green’s decision about whether he will file for a presidential disaster declaration that will help individuals and business owners secure funding for repairs.

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Jul 6 • 11:00 AM EDT • Business • bigislandnow.com
A timeline of Marine Le Pen's political career and the rise of the French far right

PARIS (AP) — French far-right leader Marine Le Pen’s political fate is at stake Tuesday when a Paris appeals court is to rule on whether she may be barred to run in the 2027 presidential election.

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Jul 6 • 6:18 AM EDT • Politics • wral.com
Palworld Dev Offers Approximate Release Time for 1.0 Update, Says Players Do Not Need to Wipe Their Data but They Really Should

Palworld’s hotly anticipated 1.0 update launches this week, on July 10, and now developer Pocketpair has narrowed the release timing down, while issuing existing players an official recommendation on whether they should wipe their data for it.

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Jul 6 • 6:09 AM EDT • Technology • ign.com
Jacob Misiorowski's All-Star Game dream might come down to weather

Jacob Misiorowski has become must-see TV. Now weather and timing could determine whether fans see the Brewers ace on All-Star night.

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Jul 5 • 6:03 AM EDT • Sports • usatoday.com
Sphere Entertainment (SPHR) Stock May Trade At A Discount On Cash Flow While Earnings Look Rich

Sphere Entertainment stock has produced a very strong share price gain over the past few years, yet its valuation signals are pulling in different directions, with a Discounted Cash Flow (DCF) intrinsic value pointing to some upside while traditional market multiples suggest the shares are expensive. Over the last 3 years, Sphere Entertainment has delivered a return of about 3.9x, which puts extra focus on whether today’s price still leaves room for further upside. Recent attention on Sphere...

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Jul 5 • 2:12 AM EDT • Entertainment • finance.yahoo.com
Sphere Entertainment (SPHR) Stock May Be Cheap On Cash Flow Yet Pricey On Earnings

Sphere Entertainment has delivered very strong share price gains over the last three years, yet the valuation signals are pulling in different directions, with the Discounted Cash Flow (DCF) intrinsic value estimate pointing to some upside while market based multiples look stretched. Sphere Entertainment has returned roughly 387.2% over three years, which puts a spotlight on whether recent gains already reflect most of the good news in the story. Expectations around demand for The Wizard of...

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Jul 4 • 5:38 PM EDT • Entertainment • simplywall.st
Universal Health Services (UHS) Stock May Trade At A Discount On Medicare Payment News

Universal Health Services stock has rebounded in the short term but is still down sharply year to date, which sits alongside valuation checks that currently paint the shares as looking cheap rather than stretched. After falling 28% year to date, Universal Health Services now raises the question of whether the recent bounce is simply a recovery from depressed levels or a sign that value investors are stepping back in. Expectations for solid earnings and ongoing support from Medicare payments...

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Jul 4 • 4:08 PM EDT • Health • finance.yahoo.com
Miss Manners: My friend can’t stop talking politics at our parties

A host is frustrated with a friend who constantly brings up politics at parties despite being asked to keep the mood light, and wonders whether they must continue inviting him since he lives nearby.

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Jul 4 • 6:00 AM EDT • Politics • al.com
Poll: Americans are willing to bridge political divides at July Fourth parties, over dinner and more

But they’re sharply divided over whether they would be willing to marry or live with partners with whom they strongly disagree politically.

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Jul 4 • 5:00 AM EDT • Politics • nbcnews.com
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Oura Ring 5 In-Depth Review: Smaller yes, but still worth it?

The Oura Ring 5 In-Depth Review, covering accuracy, new features, size comparisons, and plenty more. I dive into whether or not it's worth it.

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Jul 3 • 10:40 AM EDT • Technology • dcrainmaker.com
86% of fans say live sports are becoming a luxury experience

Davey Chadwick from YouGov Sport examines whether live sports are now reserved for well-off Americans.

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Jul 3 • 6:00 AM EDT • Sports • yougov.com
Backers of online sports betting in Nebraska submit signatures to get on 2026 ballot

The question of whether online sports betting should be legal in Nebraska will likely come before voters this November.

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Jul 2 • 11:27 AM EDT • Sports • 1011now.com
House panel explores direct health contracting to lower costs

The House Education and Workforce Subcommittee on Health, Employment, Labor and Pensions July 1 examined whether direct health care contracts between employers and providers could help address rising health care costs.

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Jul 2 • 11:02 AM EDT • Health • aha.org
The real test for AI in healthcare is making care more human

The healthcare AI market is on track to reach $491 billion by 2032. The real test of success will be whether the technology makes care feel more human.

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Jul 2 • 7:00 AM EDT • Health • weforum.org
A Nation Larger Than Its Politics

As America approaches its 250th birthday, I find myself wondering whether we have lost sight of something that earlier generations understood instinctively.Americans have never agreed on politics.We have argued over wars, taxes, immigration, religion, civil rights, economic policy, and the proper ro...

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Jul 2 • 12:50 AM EDT • Politics • thefulcrum.us
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Judge orders Pentagon to lift policy requiring journalists to be accompanied by an escort

It was not immediately clear whether the order applied only to reporters from The New York Times, which filed the lawsuit, or to the entire press corps.

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Jul 1 • 6:34 PM EDT • Politics • pbs.org
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Backers of online sports betting in Nebraska submit signatures to get on 2026 ballot

The question of whether online sports betting should be legal in Nebraska will likely come before voters this November.

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Jul 1 • 2:08 PM EDT • Sports • nebraskaexaminer.com
SpudCell: Scientists Made a Cell With Most of the Hallmarks of Life. Here’s What to Know.

From why it was created to whether it’s alive, here’s what to know about SpudCell, the latest advance in synthetic biology.

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Jul 1 • 10:39 AM EDT • Science • nytimes.com
Is the GOP race for Colorado governor heading into mandatory recount territory?

Not yet — not until the race tightens further as election officials tally more votes. The race for governor in the Republican primary between state Sen. Barb Kirkmeyer and ministry leader Victor Marx tightened on Tuesday night to roughly 1,400 votes, but whether a mandatory recount is triggered will depend on whether the margins shrink […]

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Jul 1 • 10:32 AM EDT • Politics • coloradopolitics.com
Only the midwest saw US population growth in every state. Will new residents change its politics?

Lower costs in Indiana, Iowa, Kentucky and Ohio raise questions about whether Republican strongholds will shift

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Jul 1 • 9:00 AM EDT • Politics • theguardian.com
Sony will cease production of discs for new PlayStation games in 2028

New games sold for PlayStation consoles will only be available digitally and won’t be sold on discs effective January 2028, Sony has announced. The move applies to all PlayStation games released from that point on, including those made by Sony and those released by third parties. The PlayStation group calls the change “a natural direction for Sony Interactive Entertainment to adapt to consumer trends as the general preference for digital media significantly outpaces physical discs,” according to a PlayStation blog post reviewed by Game File in advance of its publication. As movies, TV and music have shifted from physical media to an age of downloads and streaming, Sony’s move could speed the demise of physical media in a gaming. The industry has offered consumers games via cartridges, cassettes, floppy discs, CDs, DVDs and Blu-Rays across a 50-year stretch. Sony has been reporting to investors in recent years that PlayStation games have been increasingly purchased as downloads, not as discs. The most recent figures show nearly four in five purchases of full games for PlayStation 4 and PlayStation 5 were purchased digitally in the past year. Stats like that may cause today’s news to carry an air of the inevitable. But Sony’s declaration for 2028 is still likely to produce a shock, as the biggest gaming platform on the planet that uses game discs leaves them behind. Discs going away, but the fate of game boxes is unknown Sony is committing to still selling games in physical retailers even after they drop discs in 2028. Just how those games will be sold—in boxes with codes inside, as cards marked with digital redemption codes—is unclear. Digital games will also continue to be sold in the online PlayStation Store. New games released for PlayStation consoles prior to January 2028 will be unaffected by the policy change, Sony says. That means the PS5 games of 2027, be they a new Madden, a new God of War, a new Call of Duty, a new Sly Cooper (one can dream?), would still potentially be offered on disc. PlayStation 6 implications Sony’s timeline for a transition to a no-disc era will also spin up more speculation about the timing and configuration of Sony’s next-generation console, the probable PlayStation 6. “This pretty much guarantees that PS6 won’t arrive until 2028 at the earliest,” Piers Harding-Rolls, senior games research analyst at Ampere Analysis tells Game File. Harding-Rolls also concludes from today’s news that “the base version of a PS6 will not include a physical media drive,” as Sony looks to keep costs down on the device. Sony itself is saying nothing about the PS6 today: not its timing, nor how it might or might not support internal or external disc drives in order to run disc-based PS4 and PS5 games, should the console be backwards compatible. The many signs this was coming Industry support for games being released on physical media has been waning. As has consumer interest in them. PC games effectively went all-digital years ago, thanks to the popularity of playing games through Steam and other digital storefronts. The Covid-19 pandemic and the lockdowns that kept much of the global population home helped shift shopping patterns toward downloads. Sony’s own data shows PlayStation game downloads being an uncommon consumer choice a decade ago and now becoming the norm. On consoles, physical media has been in such decline that Sony and Microsoft both launched their current gen Xbox Series and PS5 consoles in 2020 with cheaper versions that lacked disc drives. In early 2024, Phil Spencer, then head of Xbox, told me that ““[w]e ship games physically and digitally, and we’re really just following what the customers are doing.” He added that the game industry had become an outlier in still supporting disc-based entertainment, even as movies and TV have bailed on discs in favor of downloads and steaming: “Gaming consoles themselves have kind of become the last consumer electronic device that has a drive. And this is a real issue, just in terms of the number of manufacturers that are actually building drives and the cost associated with those. And when you think about cogs that we’re going to go put in a console—and as you have fewer suppliers and fewer buyers—the cost of the drive does have an impact.” Last year, the Nintendo’s Switch 2, which uses cartridges rather than discs, introduced the concept of game-key cards, which are physical media that contain no game, just a prompt for a download. Even disc-based games aren’t what they once were, now frequently containing just stubs of games rather than the whole thing. The website Does It Play has tested over 3000 games and found that, for example, that the disc version of this year’s hit 007: First Light, only contained the game’s first mission, with the rest needing to be downloaded. Beyond all that, last week brought the news that Grand Theft Auto VI, likely the biggest game launch this decade, will debut for PS5 and Xbox Series without a disc-based version. Today’s big news comes to you for free. Game File is a reader-supported publication. To receive new posts and ensure more of my work is possible, please consider becoming a free or paid subscriber. Subscribe Discs helped define PlayStation However the trends in entertainment may be going, it is still remarkable to see PlayStation ditch discs given their importance in PlayStation history: In the late 1990s, the first PlayStation’s support for games on relatively cheap CD-ROMs instead of traditional game cartridges allowed the upstart console to outmaneuver cartridge-based systems from Nintendo and Sega, as it drove down game prices down in the process. (The cheaper disc format even prompted Final Fantasy VII maker Square to taunt Nintendo in a magazine ad, saying that if the game was “available on cartridge, it’d retail for around $1200.”) PlayStation devices often doubled as machines for watching movies and TV on the latest disc-based formats. In the late 2000s, for example, Sony’s pricy PS3 gained traction as a go-to device for playing then-novel Blu-Ray discs. In 2013, Sony effectively roasted the digital game-sharing restrictions proposed by rival Microsoft for its upcoming Xbox One console by showing how games could be shared for the then-upcoming PS4. In a 21-second clip that has over 20 million views on YouTube, one PlayStation executive simply handed a game box—presumably with disc inside—to another, who said “thanks.” Sony’s possible motivations The PlayStation announcement today cites “consumer preferences” and a shift away from discs among “the broader entertainment industry,” but does not delve into the decision-making process that brought Sony to this point. Sony is not discussing the economics of this move (I asked!), but there are a number of potential factors: Abandoning discs will spare Sony the cost of manufacturing and shipping them, which analysts and industry veterans I spoke to said could account for $1 or so of a game’s retail price. For first-party games, that’s direct savings for Sony, though the amount is limited by the winnowing percentage of people who were even buying the disc-based versions. For third-party games, Sony could pass the savings on to partners or just retain the better profit margin for themselves. As the 2024 comments from Phil Spencer alluded to, leaving discs behind could mean leaving disc-drives behind, allowing Sony to produce consoles more cheaply. Switching to digital-only for games could diminish the risks of copies of new games leaking. It would also seemingly make second-hand sales of used games impossible, pushing more people to buy their own copies of games. These economic benefits for Sony could be boons for the games industry overall, Ampere analyst Piers Harding-Rolls tells Game File. Among other things, it could free publishers and retailers from having to worry about securing an inventory of game discs when trying to sell games, he noted. “If there is a way to streamline the business of games retail, I generally think it’s a good thing for the industry as it removes unnecessary costs,” Harding-Rolls said. “This will help offset pressure on margins from other directions – development and staffing costs for example.” Should the industry shift from game boxes that contain discs to smaller, cheaper game cards, Harding-Rolls said, that reduces pressure on publishers and retailers. “The advantage of everything going digital for the industry is that sales can be tracked much more easily and there is less commercial risk for publishers wanting to continue selling via retail,” he said. The shift to no discs will also likely impact game development timelines, as developers will no longer face the same urgency to have a build ready to submit to PlayStation for the production of a disc, as industry experts noted around GTA VI’s no-disc news last week. Instead, projects may gain weeks of development time, in the event delivery deadlines for platform approval move closer to release date. Preservationists’ likely worries While millions of gamers have shifted to digital, there are still people who associate game discs—and only game discs—with actual ownership of PlayStation games. That portion of the gaming community spoke up last week about wanting to buy a version of GTA VI that they could hold in their hands, could lend to a friend and could potentially pop into a well-preserved PS5 console three decades from now and still see it run. Such gamers didn’t want to worry that they’d merely purchased a digital copy that could lose access to the game if, say, the company behind the game someday turns of the servers that transmit downloadable copies. Digital copies of games are inherently less long-lasting, because consumers aren’t actually buying a game (on a disc), just buying access to the game. The fine print in online gaming shops notes this, as does a recent law that went on the books in California in 2025. That lasw requires game publishers doing business in the state to refrain from words like “sell” when offering digital copies of games, unless they explicitly tell consumers that what’s being sold isn’t the game itself but a potentially revocable license to access it. A Sony spokesperson noted to Game File that “[w]ith all digital content, including games, movies, and music, players are purchasing a personal license for non-commercial use.” Regarding the fears of PlayStation games being lost to time in an all-digital era, the rep also noted that Sony remains “committed to delivering experiences from past generations to the new platforms our players are using.” They noted that PlayStation has used emulation and remasters to keep offering its classic games to modern gamers. It’s true that many consumers have become accustomed to not having physical copies of new music albums or movies, but the relative precariousness of digital copies of games is in fact being highlighted today by…. Sony’s other big announcement: the upcoming closure of the PS3 and PS Vita online stores Sony said today that it will be closing the online marketplaces for its PlayStation 3 console and PS Vita handheld in most countries in July 2027 (sooner elsewhere: August 2026 for the PS3 store Mexico, Honduras and Nicaragua; late 2026 for PS3 in other Latin American countries and the Middle East). “We know this news may be disappointing to PS3 and PS Vita players who hold a special place in their hearts for this generation of gaming,” Sony said in its announcement, saying the move “was not an easy decision for us to make.” Sony said that PS3 and Vita marketplaces “are no longer able” to support modern commerce systems, prompting a “need” to close the shops and focus on more modern PlayStation platform stores. The news may spark some deja vu. Sony announced back in March 2021 that it planned to take the PS3, Vita and PlayStation Portable marketplaces offline that summer. The move would have caused some 2,000 digital-only games to become unavailable for new purchasers, according to a VGC analysis at the time. Fans complained loudly. By April 2021, Sony walked back the PS3 and Vita shop closures, with then PlayStation boss Jim Ryan saying “it’s clear that we made the wrong decision here.” This time around, Sony is giving a longer notice period in most regions. The closure of those stores is still likely to cut off access to new purchases of digital-only PS3 and Vita games. The current PlayStation 5 marketplace sells PS5 and PS4 games, as well as a selection of PS1 and PS2 games. It does not sell PS3 games, because games for that platform can’t run on the system (some are offered via a PlayStation Plus streaming option). Vita games also aren’t sold via PS5. Sony says digitally purchased PS3 and Vita games will be downloadable after the stores’ shutdowns “for the foreseeable future.” Sony’s move contrasts with Microsoft’s Xbox platform, which continues to sell and support games from all four Xbox console generations. But it puts it in line with Nintendo, which disabled purchases in the marketplace for its Wii console (a contemporary of the PS3) in 2019. Nintendo discontinued purchases in the online shop for its 3DS portable (a contemporary of the Vita) in 2023. The big questions about Sony’s 2028 post-disc era Will Microsoft follow suit, ending support for new disc-based games on Xbox platforms and therefore all game consoles, too? Whether Microsoft does or not, will third-parties that can no longer release games on discs for PlayStation, simply ditch the disc options across the board? Given the GTA VI no-disc experiment launching this November, will more game publishers decide to forgo disc-based offerings even in 2027? How will no-disc PS5/6 games be packaged and sold in brick-and-mortar retail stores? What becomes of game sharing in an all-digital era? Will Sony modify its current set-up, which currently allows some sharing of digital games across a pair of consoles, to allow more casual lending? (See for example, Nintendo’s year-old system of letting players lend a digital game to another player in a “family group” for up to 14 days.) Will there be a version of a PS6 with a disc drive? Or will a drive be offered as an add-on? And how will gamers who want to retain access to PS4/PS5 disc-based games react to whichever configurations Sony chooses to offer? What will the final disc-based PlayStation game be?

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Jul 1 • 8:00 AM EDT • Technology • gamefile.news
Scared to Take on a Challenge? Science Says It Will Instantly Seem Easier When You Imagine Facing it With a Friend

Research shows the presence of social relationship, whether real or imagined, will change how difficult a challenge appears to be.

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Jul 1 • 5:42 AM EDT • Science • inc.com
Wilmington Small Business Coalition: Building Momentum in 2026 by Heather McWhorter

This article was contributed by Lydia Thomas, UNCW CIE Program Manager. North Carolina continues to be one of the best states to start a business and in 2025, Wilmington, North Carolina earned a spot on the GoDaddy list of the top 10 most entrepreneurial cities in the U.S. While many know Wilmington as small beach town with exceptional food, lots of coffee shops, and fun, vibrant summer activities, a closer look reveals a thriving innovation economy. You’ll find startups emerging across industries including software, healthtech, bluetech, and fintech. At the core of this entrepreneurial ecosystem is the Wilmington Small Business Coalition, with small business advocates and entrepreneur support organizations (ESOs) dedicated to helping founders grow, thrive, and succeed. “No Wrong Door” Established in 2016, the Coalition was designed to make it easier for individuals and small businesses to access resources most suited to their particular needs. The Coalition is designed to have a “no wrong door” entryway into the regional startup ecosystem. Whether you are exploring a new idea sketched on the back of a napkin or leading a more established, growth-stage company, Coalition members can help connect you with the programs, funding opportunities, mentors, and resources best suited to your needs. No matter where you are in your entrepreneurial journey, any Coalition organization can help point you in the right direction. Coalition Members and Leadership Coalition members include the UNCW Center for Innovation and Entrepreneurship (UNCW CIE), AARP, Brunswick Community College Small Business Center, Cape Fear Community College Small Business Center, Cape Fear Region SCORE, Genesis Block Foundation, Network for Entrepreneurs in Wilmington (NEW), Small Business & Technology Development Center (SBTDC), Greater Wilmington Chamber of Commerce, YWCA Living the Dream Center for Entrepreneurship, Carolina Community Impact Fund (CCI Fund), Partner Community Capital, 717mkt Office Collaborative, NC Biotech, and Institute NC. In May 2026, the Coalition held its leadership elections, resulting in the selection of a new executive team. The following officers were elected to serve two-year terms: Chair: Lydia Thomas, UNCW CIE Vice Chair: Diane Lantz, CCI Fund Secretary: Aariene Hansley, Genesis Block Foundation Treasurer: Gloria Monroe, SBTDC Vision for the Wilmington Small Business Coalition In 2026, the Wilmington Small Business Coalition continues its work as a collaborative network of organizations. By connecting programs, expertise, and services across partner organizations, entrepreneurs can more easily find the right support at the right time. Rather than operating in silos, the Coalition aims to function as a unified, cohesive system of support for small businesses and entrepreneurs, ensuring that resources and expertise across partner organizations are visible and accessible. Through stronger collaboration and shared pathways, entrepreneurs can move more seamlessly from idea to startup to growth. Looking to dive into the Wilmington entrepreneurial ecosystem? Connect with any of the Coalition partners to get started! Connect with CIE To learn more about CIE and our services, programs, and events, join the CIE newsletter. You can also follow us on social media: Instagram, Facebook, LinkedIn, TikTok, or YouTube. CIE’s website is uncw.edu/cie. Heather McWhorter is the director of the UNCW Center for Innovation and Entrepreneurship (CIE). CIE supports innovation-forward start-ups and helps to build a vibrant innovation economy for all in southeast NC.

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Jun 30 • 8:00 PM EDT • Business • wilmingtonbiz.com
Federal changes lead to thousands of New Yorkers losing their health insurance

To find out whether you’re eligible, visit the New York State of Health website to apply for the tax credits.

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Jun 30 • 7:30 PM EDT • Health • spectrumlocalnews.com
Trump announces Republican midterm convention in Dallas in September

President Donald Trump has announced that Republicans will hold their first-ever national convention ahead of the midterm elections, an unusual event aimed at boosting turnout in races that will decide whether the party maintains control of Congress.

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Jun 30 • 6:46 PM EDT • Politics • pbs.org
Trump announces midterm convention for Republicans in Dallas in September

The event is aimed at boosting turnout in races that will decide whether the party maintains control of Congress

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Jun 30 • 6:14 PM EDT • Politics • spectrumlocalnews.com
Wimbledon: The Serena comeback was beautiful, thrilling and probably impossible

Four years after we last saw her on a singles court, it was hard to tell whether Williams' return to Wimbledon was the beginning of a new chapter or an attempt to author a different end.

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Jun 30 • 6:06 PM EDT • Sports • sports.yahoo.com
Supreme Court agrees to review ban on AR-style semi-automatic rifles in major Second Amendment case

The Supreme Court announced Tuesday that it will decide whether cities and states may ban people from owning AR-15 rifles and similar semiautomatic weapons, taking up a major Second Amendment dispute that it had previously declined to address.

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Jun 30 • 12:16 PM EDT • Politics • cnn.com
Dave Portnoy discusses whether he'd run for political office

Barstool Sports founder Dave Portnoy discusses tourists coming to the U.S. for the World Cup, New York City Mayor Zohran Mamdani's policies and whether he'd ever run for political office on ‘Jesse Watters Primetime.’

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Jun 29 • 8:52 PM EDT • Politics • foxnews.com
Scientists say creatine may help fight depression

Creatine is best known as a muscle-building supplement, but scientists are now investigating whether it could also help treat depression by boosting the brain's energy supply. A new review examined five randomized clinical trials involving 238 participants and found mixed results. Two studies, both involving women with major depressive disorder, reported that adding creatine to standard treatment improved symptoms, while three others found no meaningful benefit.

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Jun 29 • 8:00 PM EDT • Science • sciencedaily.com
Professor known for 'torture memos' will advise conspiracy probe focused on perceived Trump foes

John Yoo, a conservative law professor known for his views on presidential power, confirms he will advise a team investigating whether officials conspired against Donald Trump.

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Jun 29 • 7:16 PM EDT • Politics • pbs.org
Why Girls In Sports May Be More Likely To Lead, And How Coaches Help

94% of C-suite women played sports as youth. There is one type of leader that has a big impact on whether girls want to play and stay in sports: The coach.

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Jun 29 • 6:24 PM EDT • Sports • forbes.com
Colorado court rejects November ballot initiatives aimed at redrawing congressional districts

Colorado voters won’t get to decide this November on whether to change the state’s congressional districts to favor Democrats

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Jun 29 • 6:06 PM EDT • Politics • washingtonpost.com
Netflix and Superheroes Are Having a Rough Stretch on Streaming....

(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) I have a quick prediction before we start today’s article: You might see this data in future news articles. Not my specific charts or analysis, but the core trend I’ve been monitoring—Netflix is having a lackluster Q2—will become inescapable. Often, folks want to know “What does the data say?” Well, that’s what it says. I haven’t seen this analysis hit the trades really yet, but I have a feeling some other outlets are going to start making this case soon. Remember, you read it here first. You probably have read about the problems facing superhero films at the box office this weekend. Well, this week, I explore whether superheroes are dying on TV as well! And the data says: definitely maybe! We have a lot to cover in today’s Streaming Ratings Report, which covers the two weeks of 18-May and 25-May. Today, I’m just looking at TV, like Netflix’s disappointing Q2, superhero shows underwhelming, a few TV shows dropping off the charts, The Pitt finally ending its epic run on the viewership charts (and whether “view counts” change its status as one of the biggest shows of all time), all the flops, bombs and misses, and a whole lot more. Tomorrow, I’ve got a great rundown of the film side of things. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, Showlabs, TV Time trend data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of May 18th to May 31st, 2026. You can find a link to my terminology here.) Subscribe Television - Netflix’s Q2 Slump Continues Having analyzed streaming ratings for going on half a decade, I have learned to trust my gut, but I’m always relieved when I can find actual data to back it up. For example, after a string of very popular shows like Stranger Things, Bridgerton, The Lincoln Lawyer and The Night Agent came out, week after week, in January and February, my gut wondered if Netflix had enough new and returning TV shows to sustain them throughout the year. Since then, Netflix’s post-March slate of shows has not impressed me. This week seemed to feature a potential new hit, but then, like a classic Duffer Bros. TV show, there was a twist. I speak of The Boroughs, Netflix’s latest (and last) Duffer Bros. produced show. The pitch is “Stranger Things with older actors”. And it topped the Nielsen charts: With just two weeks of viewership, The Boroughs would have been a top 25 debut show last year: But here’s the twist: Netflix has already cancelled The Boroughs! What happened? Likely a few things. First, the show didn’t do as well globally as it did in the US. As What’s on Netflix showed, it lagged behind several other shows that got cancelled. Second, its completion rate was likely low; after an initial burst of interest, it quickly dropped off on the Samba TV and Luminate charts. Third, the Duffer Bros. left Netflix for Paramount, and that may have factored into Netflix’s decision here. (Though I tend to believe that if a show is doing well, Netflix would have kept greenlighting seasons.) Still, just because I can explain why Netflix may have cancelled this show doesn’t mean I’m justifying it. In particular, as I’ve noted before, Netflix is losing a lot of their bigger shows as they reach their natural ends, and they need to replace those shows. This show had the hallmarks of a big new genre show, and it’s their biggest hit of the last few months (in the US at least), but now it’s done. Netflix’s other show this week—The Four Seasons, the second season of the “hit” show from last year—definitely disappointed. Its sophomore season had about half the viewership of the first, only 12.7 million hours. It also only had a two week run on Samba TV, and its numbers were all down on Luminate too. In other words, even with two successes, the Q2 slump for Netflix looks real: I could add to the list of disappointments: Both Lord of the Files and Man on Fire had short runs on the Nielsen charts. Running Point’s sophomore season also opened to about half its viewership, similar to The Four Seasons. A Good Girl’s Guide to Murder’s second season—see below—didn’t even make any of the three viewership charts I track, unlike the first season. Netflix is absolutely having a dismal second three months of 2026. If this Nielsen data is any indication, and I think it is, I think this will show up in Netflix’s engagement report, and maybe even their financial outcomes. And the rest of June doesn’t look much better. We have two hit shows coming back—Sweet Magnolias, one of their quietest big shows, and Avatar: The Last Airbender, a big hit for them in 2024—but the other big swings are limited series crime thrillers i.e. no future season potential. Like I said above, sometimes when I uncover a juicy nugget like this, other outlets end up writing very similar articles mimicking the data without credit. We’ll see if that happens this time! Share Television - The State of Superhero Shows on Streaming When I first heard the pitch for Spider-Noir—a Sony TV show on Prime Video that binge-released eight episodes first on MGM+ then on Prime Video two days later—I had my doubts. It’s a live-action Spider-Man show set in the 1930s, starring Nicholas Cage, based on a cameo of a character in Spider-Man: Into the Spider-Verse. No, seriously, that’s the pitch. That could either go terrifically well or horribly wrong. Great because, Spider-Man. He’s the biggest superhero we have. I’ve seen tracking numbers that put the new _Spider-Man: Brand New Da_y as the blockbuster of the year and initial pre-sales back that up. And yet this Spider-Noir pitch feels very esoteric. (Also, the eight-episode binge release feels very “Amazon copying Netflix” again.) So what’s the data say? And what does this say about the future of superhero shows?

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Jun 29 • 5:43 PM EDT • Entertainment • entertainment.substack.com
Rocket Lab expands satellite business with Iridium deal

Yahoo Finance Senior Autos Reporter Pras Subramanian joins Market Domination to discuss Rocket Labs' (RKLB) deal to purchase Iridium Communications (IRDM), how the deal expands its satellite capabilities, and whether it strengthens the company's position against SpaceX (SPCX).

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Jun 29 • 3:42 PM EDT • Business • finance.yahoo.com
Scientists Slam Trump Rule Change

Dr. Esen Sefik moved from Istanbul to New Haven 20 years ago because she believed the U.S. was the best place to do scientific research. Now, her advisees are wondering whether to stay in their home countries instead. Sefik described the U.S.'s changing research climate on Monday during a press conference about a proposed rule by the Trump administration that would require a political appointee to approve all discretionary federal grants.

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Jun 29 • 2:51 PM EDT • Science • newhavenindependent.org
Housing bill that Trump refuses to sign heads to his desk

House Speaker Mike Johnson is set to send a bipartisan housing bill to President Donald Trump’s desk Monday, but it is unclear whether he will sign it into law.

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Jun 29 • 11:13 AM EDT • Politics • washingtonpost.com
Nintendo has suddenly announced a new Direct livestream for tomorrow

Whether you are a kid or a squid, you can tune in for more details on the single-player adventure game.

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Jun 29 • 10:33 AM EDT • Technology • eurogamer.net
How the Mass Shooting at Bondi Beach Shattered Australia’s Political Consensus

After the country’s most deadly act of gun violence in nearly thirty years, some politicians asked whether the real problem wasn’t gun control but antisemitism. Were they right?

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Jun 29 • 6:00 AM EDT • Politics • newyorker.com
The last, best hope for the Colorado GOP

If the Colorado Republican Party desires to retain any relevancy, let alone wrest back any of the levers of political control in the state, it needs to elect Barb Kirkmeyer in the June 30 primary. To be sure, Kirkmeyer would be a solid candidate for governor in any case, whether or not she shared the […]

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Jun 29 • 2:30 AM EDT • Politics • coloradopolitics.com
Restructuring safety

The real question isn’t whether safety survives a restructuring; it’s where the cracks appear first – and whether anyone is looking.

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Jun 29 • 1:15 AM EDT • Health • safetyandhealthmagazine.com
Seahawks Get Big Rashid Shaheed Update Ahead of Training Camp

The Seattle Seahawks have Jaxon Smith-Njigba as their WR1, but the question will be whether Rashid Shaheed can become a WR2. Last season, the Seahawks traded a fourth-round pick and a fifth-round pick in the 2026 NFL Draft to the New Orleans Saints for Shaheed. Moreover, Shaheed didn’t become a rental for the Seahawks, as […] The post Seahawks Get Big Rashid Shaheed Update Ahead of Training Camp appeared first on HEAVY.

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Jun 28 • 8:29 PM EDT • Sports • sports.yahoo.com
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial

Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to

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Jun 28 • 3:45 PM EDT • Health • astrazeneca-us.com
Scientists Publish Extremely Serious Research About Whether Tickling Apes Makes Them Giggle

Scientists tickled apes and examined their laughs to gain some very serious insights into primate evolution.

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Jun 28 • 11:51 AM EDT • Science • futurism.com
Eat, Sip, Shop: New businesses bring unique products, services to Bethlehem’s Main Street

Whether you’re shopping for toys, games and puzzles or jewelry, home decor and pet treats and accessories, a variety of new retailers on downtown Bethlehem’s Main Street have you covered.

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Jun 27 • 11:05 AM EDT • Business • wfmz.com
After ousting Bill Cassidy, Donald Trump faces fresh test of his sway with GOP voters in Louisiana’s Senate runoff

Louisiana Republican voters already rejected an incumbent senator who was crossways with President Donald Trump. In a primary runoff on Saturday, they’ll decide whether to follow Trump’s lead in choosing a new nominee.

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Jun 27 • 6:30 AM EDT • Politics • cnn.com
How to use AI in your dating life responsibly and effectively

Whether you love or loathe generative AI chatbots, they’re becoming increasingly involved in the business of romance.

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Jun 27 • 5:00 AM EDT • Technology • apnews.com
High-Signal Publisher
Siekerka on Spadea: Climate Superfund Another Strike at NJ Business Climate

Appearing on Bill Spadea’s new show, Speak for America, on ONNJ, NJBIA President and CEO Michele Siekerka said it’s difficult to determine whether the

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Jun 26 • 10:53 PM EDT • Business • njbia.org
Politics Unplugged Podcast: Headlines with Stacy Pearson and Marcus Dell’Artino

The Politics Unplugged panel breaks down a possible Arizona special session tied to ESA vouchers, union protections and ballot measures. The discussion centers on whether lawmakers could unwind late-night legislation that angered teachers, police and firefighters. They also examine Gov. Katie Hobbs’ political leverage and why both parties may have reasons to cut a deal. Later, the podcast turns to Trump tax cuts, Democratic Socialists, the White House reflecting pool controversy and the World Cup.

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Jun 26 • 10:15 PM EDT • Politics • azfamily.com
☹️ Negative (-8%)
Falcons Roundtable: Kyle Pitts Extension Done, Is Bijan Robinson Next?

The Falcons continue to lock up the core of their roster for the future. This week's Falcons Roundtable breaks down Kyle Pitts' new extension, whether his deal or Drake London's is the better value, and why Bijan Robinson appears to be the next superstar in line for a record-setting contract.

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Jun 26 • 5:50 PM EDT • Sports • sports.yahoo.com
Iran's Pride Match is about visibility, not politics

Iran’s World Cup match against Egypt has become a test not only of FIFA’s approach to inclusion but also of whether LGBTQ+ Iranians can claim visibility on one of the world’s biggest sporting stages.

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Jun 26 • 12:20 PM EDT • Politics • iranintl.com
Sweden and WHO launch new long-term initiative to transform Ukraine’s health system

WHO and the Swedish International Development Cooperation Agency (Sida) have launched a new multi-year cooperation project to support the long-term recovery and transformation of Ukraine’s health system. The new project, “Ukraine’s Health System Transformation Initiative: Strengthening Health Governance, Health Financing and Service Delivery for Long-Term Recovery”, was launched at the Ukraine Recovery Conference 2026 in Gdansk, Poland on 26 June, and will run from June 2026 to 2029. Sweden will contribute approximately US$ 26 million (240 million Swedish krona) to support this project. This contribution forms part of Sweden’s broader support to Ukraine through the Team Europe approach, which brings together the European Union, its Member States, and key partners such as the European Commission’s Directorate-General for Enlargement and Eastern Neighbourhood and Enabel, and WHO as lead health agency, to support Ukraine’s recovery, reform agenda and European integration.“Ukraine’s health recovery cannot be measured only by what is rebuilt, but by whether people can count on the health system when they need it most. The scale of the task is immense, with health reconstruction and modernization needs estimated at US$ 19.4 billion over the next decade. Sweden’s US$ 26 million contribution to Ukraine’s Health System Transformation Initiative is a timely investment in the institutions, financing and services that will support Ukraine’s long-term recovery and European integration. WHO remains a trusted partner of the Government of Ukraine in advancing this process. I am deeply grateful to Sweden for its consistent support and partnership,” said Dr Hans Henri P. Kluge, WHO Regional Director for Europe. More than 4 years of war have placed unprecedented pressure on Ukraine’s health system, creating 3 interconnected challenges. The first is responding to the immediate consequences of the war and the urgent health needs of the population. The second is recovering and modernizing health services today. The third is continuing reforms and aligning the health system with European standards in the context of Ukraine’s future accession to the European Union. The war has led to large-scale population displacement, an increasing need for trauma care and rehabilitation, and shortages of health workers. High out-of-pocket payments in Ukraine make access to health services more difficult. Around 46% of total health expenditure is paid directly by individuals, placing a significant financial burden on many households and underscoring the need for reforms in health financing. Older people, persons with disabilities, women, children and veterans continue to face the greatest difficulties in accessing health services. “Ukraine is demonstrating that health system transformation can continue even during war. Ukraine is also continuing to align its health system with European norms and standards. WHO is committed to supporting Ukraine on this journey. We provide technical support, help coordinate partners’ efforts and support the institutional changes needed to strengthen the system. We are grateful to Sweden for its support. Through this partnership, we can help Ukraine build a more resilient, accessible and people-centred health system,” said Dr Jarno Habicht, WHO Representative in Ukraine. About the Health System Transformation InitiativeThe new initiative will support Ukraine through 3 interconnected areas: strengthening governance and coordination of health sector reforms through more inclusive coordination platforms and structured policy dialogue; transforming service delivery by reinforcing a primary health care-centred model that integrates family medicine, nursing and midwifery; and improving financial sustainability by supporting reforms that ensure the long-term viability of the national health system and reduce out-of-pocket payments for households. Overall, these reforms are expected to make the health system more coherent and easier to navigate, improve the quality and continuity of care, and ensure more equitable access to services, particularly for those who need them most. They will also support Ukraine’s progress towards a more modern health system aligned with European standards. “We are convinced that long-term recovery is not possible without strong, high-quality, person-centred health services that are accessible to everyone. Our partnership with WHO is designed to support deep and lasting systemic changes. Investments in human capital especially autonomous midwives, whose role for maternal, newborn and adolescent sexual and reproductive health cannot be understated, stronger governance, digital transformation and the financial sustainability of the health system are investments in Ukraine’s future. We are proud to support this process,” said Malin Perhult, the Head of the Ukraine Unit at Sida. Focus throughout implementation will be given to the most vulnerable population groups, including older people, women and children, and persons with disabilities, who have been affected by the war and face greater health-care needs. The initiative will be implemented in close cooperation with the Ministry of Health of Ukraine, the National Health Service of Ukraine, the Public Health Centre of Ukraine, regional authorities and international partners. This project will help Ukraine move towards a system where everyone can access the health care they need. It will strengthen primary care, make the health finance system more stable and predictable, and reduce the out-of-pocket costs that Ukrainians face when using health services. As a result, the Ukrainian health system will become more aligned with European standards and more sustainable in the long run.

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Jun 26 • 8:00 AM EDT • Health • who.int
Justices Clash on Whether Race Played a Role in Trump’s Bid to Deport Haitians

The split mirrored one that has long divided Americans: how seriously to take the president’s loose, provocative and sometimes ugly remarks.

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Jun 25 • 5:37 PM EDT • Politics • nytimes.com
Making Our Own Luck

We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.

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Jun 25 • 4:48 PM EDT • Science • goodscience.substack.com
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Gillings-supported center helps public health teams prioritize infectious disease risks, from measles to the World Cup - UNC Gillings School of Global Public Health

June 25, 2026 When public health workers prepare for infectious disease threats, the question is rarely whether risk exists. It is where to focus first.

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Jun 25 • 12:07 PM EDT • Health • sph.unc.edu
Another look at carrots and eyesight; how to get more fiber; why mosquitoes bite some people and not others; plus other stories with Vanderbilt Health sources

AARP reporter Stacey Colino interviewed Milam Brantley, MD, Associate Professor of Ophthalmology and Visual Sciences, in 2020 for a story about whether eating carrots can improve vision. Sacramento Bee reporter Samantha Agate has now used Brantley’s comments in an AI-curated story created by content specialists on the same topic that has been picked up by MSN and others. Prevention magazine interviewed Heidi Silver, RD, PhD, Founding Director of the Vanderbilt Diet, Body Composition, and Human Metabolism Core, for a story about the importance of fiber and how people can get more of it in their diet. William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: Women’s Health (tick bites and alpha-gal syndrome); The Washington Post (tetanus); and Healthline (why mosquitoes prefer to bite some people and leave others alone). A visit to Monroe Carell Jr. Children’s Hospital at Vanderbilt by some Banana Ball baseball players was covered by The Tennessean and WZTV Fox 17 News, and The Tennessean’s story was also picked up by Yahoo! Sports. Clarksville Now published a story written by the Montgomery County Economic Development Team, whointerviewed Bradley Stancombe, MD, professor of Clinical Pediatrics, Vanderbilt Neonatology, about the new energy of Vanderbilt Clarksville Hospital and how the facility is recruiting physicians. Healio Allergy/Asthma group editorial director Richard Gawel interviewed Mark Rolfsen, MD, Clinical Fellow in the Division of Allergy, Pulmonary and Critical Care Medicine, for a story about his presentation at the American Thoracic Society meeting on metal health outcomes following ICU discharge. Nashville Scene reporter Hannah Herner interviewed James Crowe, MD, Director of the Vanderbilt Center for Antibody Therapeutics, for a story about his efforts to prepare for the next pandemic by isolating antibodies that can neutralize dangerous viruses. Medscape reporter Kathleen Doheny interviewed Neesha Choma, Associate Chief of Staff of Vanderbilt University Hospital, for a story about how hospitals can reduce readmissions.

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Jun 25 • 10:56 AM EDT • Health • news.vumc.org
Who will be the next chancellor?

Whether Andy Burnham picks Miliband, Streeting or someone else, they will face a ‘bulging in-tray’

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Jun 25 • 8:10 AM EDT • Politics • theweek.com
How should European scientists respond to the US AI kill switch?

Earlier in June, Europe’s worst fears of technological dependence were confirmed when the White House ordered the AI firm Anthropic to stop non-US citizens using its leading models. This kill-switch moment crystalised anxieties in Brussels that the continent, lagging the US on the creation of leading-edge AI models, is now a technological of vassal of Washington. The shock has specific implications for European scientists and universities. Some governments are now worried that with AI being integrated into labs, Donald Trump now has his finger hovering over an off switch for European science. “Having restrictions on this tool, it can have an impact on our own research,” said France’s research minister, Philippe Baptiste, at the VivaTech conference in Paris on June 18.Baptiste, himself a former academic, said that colleagues in mathematics had recently warned him they were now cut off from leading-edge US models, risking their work. “This model is not available anymore now because of the US restriction, and for the first time this had an impact on mathematics,” a field where large language models (LLMs) are making a significant contribution, said Baptiste. So, should European scientists avoid relying on US models in the future? Or would this be a self-harming overreaction? And how is AI being used in science, anyway? What happened?On June 12, it emerged that Washington, citing cybersecurity concerns, had ordered Anthropic to stop non-US citizens using two models: Claude Mythos 5, and Claude Fable 5, a version of Mythos but with guardrails to prevent abuse. Anthropic said Washington’s concerns were overblown. But forced to follow the order, yet with no way to check who was using the models, the company suddenly shut down access for everyone, US citizens included. There’s still no agreement on how to restore broad access. But last week, Bloomberg reported that select US companies, and the US government, still had access to Mythos despite the ban, but the EU’s cybersecurity agency Enisa had been shut out. Class division of researchersIn the longer term, access outside the US should be restored, said Marcel Salathé, co-director of the AI centre at the Federal Polytechnic School of Lausanne (EPFL), because a permanent restriction would be financially ruinous to US AI firms. “Even Trump will eventually budge to economic pressure,” he said.However, US AI firms might end up operating rather like banks, doing due diligence on users of their leading-edge AI models, he went on.European scientists are unlikely to fall foul of such checks, he said. But having a Chinese postgraduate in their lab, or doing a type of research the US disapproved of, could potentially result in access being denied. “It will create a sort of class division of researchers,” he said. More than frontier modelsHowever, successfully deploying AI in science is about far more than just having access to leading LLMs such as Mythos.Instead, many science-specific tools, most famously Alphafold, which predicts protein folding structures, require “far less” computing power to train than frontier models, well within the capabilities of European supercomputers, according to a recent analysis by the Arq Foundation, a Brussel-based AI think tank. Instead, tools such as Alphafold are possible because certain fields, like protein folding, weather prediction or astronomy, have large, clean, standardised datasets that can be used to train predictive models. Rather than compute, “data is the central constraint for AI for science,” the report says. For example, a less powerful physics model trained on CERN’s data “will be more valuable than the best model without certain data,” said Bengüsu Özcan, author of the report. European advantage?Europe could therefore steal a march by using its scientific data and infrastructure to create models US digital giants cannot. “They might actually match or go even beyond what these big [US] companies are doing,” said Özcan.Indeed, some European start-ups hope to create automated testing labs to create the kind of standardised data that could speed up the discovery of new materials. Materials scientists say there’s currently too little data to train models. AI scientistsHowever, even if the bottleneck for AI in science is often data, rather than compute, being at the mercy of the US for LLM access could still become a problem for European scientists. A new class of “AI scientists” based on leading LLMs is also emerging, Özcan’s report says.Unlike domain-specific tools like Alphafold, these try to automate day-to-day scientific work, by providing an overarching tool that coordinates specific models to synthesise existing literature, generate hypotheses or run analysis of data. The problem for Europe, however, is that these tools are sometimes based on US leading models. Google Deepmind’s AI Co-Scientist, for example, is built on Google’s Gemini LLM. Systematic failureThese scientific automation tools are still in their early stages, and still exhibit “systematic failures on scientific tasks,” Özcan’s report says. One of the problems is that the messy, day-to-day process of scientific discovery is largely not documented, meaning LLMs don’t have a good source of data to learn how scientists actually work. Meanwhile, some tasks, such as literature synthesis, don’t typically require access to leading edge models.However, the performance of AI scientific assistants could improve as companies such as Google pour resources into developing them. Rely on US“Unfortunately, for scientific assistants, there is not much we can do right now except rely on US frontier AI,” said Antoine Bosselut, a natural language processing expert based at EPFL. Chinese-built open models, which can run on local computers, lessening the risk of a shutdown, are touted as one alternative to US dependence. There’s also Mistral, once seen as Europe’s main AI hope, but the Paris-based company has seen its recent models fall behind in performance. But the Chinese alternatives are generally not as capable as US frontier AI models, said Bosselut, unless paired with fiddly, custom tools that allows them to act as independent agents. “Most scientists do not have the time,” he said. Don’t jump ship yetAlthough the kill switch moment is seen a warning shot for European scientists, it doesn’t mean labs should abandon US AI tools immediately. “I do not think the right response is simply to abandon US-based models and systems under the banner of sovereignty or independence,” said Mattias Björnmalm, secretary general of the Cesaer university association. “That would be an overreaction.”Related articlesEuropean sovereignty in AI requires ‘ugly trade-offs,’ say experts Robotic lab start-up makes case for €500M EU-funded materials testing facilityAI in science: is it useful? Instead, European researchers need to ask themselves whether they’re becoming dependent on technology that could be turned off in Washington, said Özcan. “They might not see this today, but they should really start asking this question,” she said. European researchers need a plan B, said Salathé. “I would recommend to every researcher, very proactively explore alternatives.”Own toolsIn addition, Björnmalm and others want European research institutions to develop their own scientific AI tools.Instead of signing AI deals with US digital giants, European universities should be using this money to create their own models, which may end up being superior for research, said Sabine Leonelli, an expert on the use of AI in science at the Technical University of Munich. “Universities in Europe seem to be happy to sign commercial contracts with US companies on the assumption [their AI tools] are better,” she said. But US frontier LLMs are typically opaque, and have been developed without independent scientific input, she said. “This is not good enough for science.”Last year, Swiss researchers released Apertus, an LLM designed to be completely transparent, from its development methods to its training data. The idea is that this makes scientific tools built on top of the model far more reproducible than with closed, commercial alternatives.“Europe needs more of this: serious capacity-building that gives researchers, universities and companies credible options,” said Björnmalm.

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Jun 25 • 8:00 AM EDT • Science • sciencebusiness.net
The Heart-Healthy Way to Lift Weights, Explained by a Doctor

In TODAY.com’s Expert Tip of the Day, a sports medicine doctor reveals whether it’s better to use heavier weights with fewer reps or lighter weights with more reps for a healthy heart.

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Jun 25 • 8:00 AM EDT • Health • today.com
First NYC. Now DC. Can Mamdani’s win keep powering progressives?

Candidates on the left are on a roll in the biggest, bluest cities. But doubts remain about whether they can win a national race.

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Jun 25 • 7:04 AM EDT • Politics • usatoday.com
Susan Collins is testing whether old school politics still work

In the modern era, political activists want their representatives to fall strictly in line. To the base, the independent centrist is no longer a hero; they are a villain to be purged. But Susan Collins has a pitch that she is an independent voice.

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Jun 25 • 5:30 AM EDT • Politics • bostonglobe.com
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If Virginia’s ‘best state for business’ ranking falls, data center taxation debate will get the blame

But will Virginia fall? We don’t know yet, but we do know how CNBC has changed its formula. Here’s a look at whether that helps or hurts the state.

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Jun 25 • 4:10 AM EDT • Business • cardinalnews.org
Elk River brewery owner says future of business depends on whether city approves data center next door
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Jun 24 • 11:35 PM EDT • Business • cbsnews.com
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Jasmine Crockett’s silence could hurt James Talarico’s U.S. Senate chances in November

The Dallas congresswoman, Talarico’s erstwhile rival in the Democratic primary, has yet to say whether she’ll campaign for him in the general election against Republican Ken Paxton.

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Jun 24 • 4:25 PM EDT • Politics • houstonpublicmedia.org
The 'pet effect' and how animals may boost your health

Whether you’re the proud pet parent to an animal with paws, claws, hooves or fins, it’s no secret how much joy and companionship they bring us.

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Jun 24 • 1:28 PM EDT • Health • usatoday.com
Trump abruptly cancels signing of bipartisan bill on affordable housing

The president posted on social media that the signing was off until the Senate passes his election integrity bill. It is unclear whether he intends to kill the housing bill.

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Jun 24 • 10:58 AM EDT • Politics • washingtonpost.com
Google Home Speaker review: A modest update for the Gemini era

Google's new speaker is a modest update, but the question is whether Gemini is a good smart home assistant.

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Jun 24 • 9:00 AM EDT • Technology • engadget.com
Political consultant on whether Trump is losing GOP support after war powers vote

NPR's A Martínez asks Republican political consultant Doug Heye about whether Trump is losing support among congressional Republicans after the Senate voted to limit his war powers on Iran.

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Jun 24 • 6:49 AM EDT • Politics • npr.org
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Political consultant on Trump is losing his party's support after war powers vote

NPR's A Martínez asks Republican political consultant Doug Heye about whether Trump is losing support among congressional Republicans after the Senate voted to limit his war powers on Iran.

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Jun 24 • 6:49 AM EDT • Politics • npr.org
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Valve admits Steam Machine is "more expensive" than it hoped

The PC giant is non-commital on whether the console's price will come down in the future if hardware costs reduce

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Jun 24 • 5:48 AM EDT • Technology • gamesindustry.biz
Monster Fantasy Combines the Thrill of Monster Hunter with the Cosy Chill of Animal Crossing

We got hands-on with a very early build of Monster Fantasy, a hybrid adventure that gives players the flexibility to choose whether they want to seek the thrilling challenge of big game beast-hunting or the laid back chilling of just catching bugs and good vibes with their fellow villagers.

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Jun 24 • 1:00 AM EDT • Technology • ign.com
Florida Attorney General Issues Subpoena to CVS Health in Pharmacy Probe

Florida’s attorney general says he is examining whether CVS’s pharmacy benefit manager steers patients to its own pharmacies.

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Jun 23 • 5:33 PM EDT • Health • barrons.com
Roku May Help Fox Avoid Aggregeddon

(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) Scrolling through links over the last week, I stumbled across this fun headline: Wow. Formula 1 (the sport, not the docu-series) is the perfect “dog not barking”. As a reminder, each week in my Streaming Ratings Report, I call out the shows that miss every viewership chart. I dub them “dogs not barking”—like the Sherlock Holmes mystery—because without any data, we forget they even exist. This is in contrast to something like, say, a film flop—cough The Mandalorian and Grogu cough—where even underperforming at the box office is widely discussed here, there and everywhere. In the US, Formula 1 is now in “no public viewership data, so not discussed” territory. After moving to Apple TV from its former home of ESPN, basically no one talks about it. Apple did publish an initial, unsourced, unsubstantiated, (dare I say unserious) datecdote claiming more folks are watching Formula 1 on Apple than ESPN, but we haven’t gotten any updates since. This stands in contrast to when the sport streamed on ESPN, and ESPN PR provided weekly viewership figures. Formula 1 was, at best, a niche sport in America—averaging 1.3 million viewers in the Big Data Plus era—but now it’s basically anonymous. (And yeah, after moving to Apple, I very, very, very much doubt its ratings increased.) Unfortunately, that story isn’t quite big enough to warrant a section in today’s “Most Important Story of the Week” column, but I wanted to call it out, because otherwise, no one else will! Certainly, no one will write articles about the silence/ratings decline, unlike when they wrote breathless articles connecting the rise in viewership to Netflix’s Drive to Survive, including Reuters just last month. (This is a topic I’ve tried to provide a moderate/nuanced/non-hyped take since 2022.) Anyway, on to this week’s issue. I was a bit worried I didn’t have a juicy topic, then the Murdochs went out and did their Murdoch thing: buying Roku. So that’s the story of the week, and it happens to touch on quite a few themes of the streaming wars and the disruption therein. I’ll cover that, plus why more consolidation in Hollywood media looks likely, more good news on the Hollywood labor front, whether we’ll see an uptick in production in Los Angeles, some Broadway and theme park news, cellphone prices going up in the third world (and possibly everywhere), and more. Subscribe Most Important Story of the Week - Another Big Media & Entertainment Merger The story of the week is clearly Fox is buying Roku for $22 billion. I read a lot of good strategy takes on why Fox bought this streaming TV device maker—and I’ll have mine below—but what fascinates me more is how this deal connects to quite a few themes of the streaming wars, linking to everything from the pace of M&A to “aggregeddon” to Netflix’s recent M&A actions/inactions to the shift to advertising from pure play streaming and more. The only topic I can’t really connect it to is my old theory, “never bet against Rupert Murdoch” because he isn’t the one who did this deal; his son Lachlan inked it. (Do I think he provided advice, even at his 95 years of age? Sure.) That plus I have one additional piece of strategy for all entertainment players, inspired by this deal. So let’s dive into all those topics, starting with why I like this deal. Roku is a Great M&A Buy

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Jun 23 • 2:23 PM EDT • Entertainment • entertainment.substack.com
Christian Gonzalez Could Force Patriots Into Awkward Training Camp Standoff

There are no official deadlines in late June or early July in the National Football League. In New England, though, all eyes remain on the Christian Gonzalez contract situation and whether or not he becomes the next young, budding defensive superstar to be rewarded with a mega-deal. Gonzalez, the team’s first-round pick in 2023, has one Pro Bowl and one monster playoff run that has people talking about him like he's an elite corner.

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Jun 23 • 12:30 PM EDT • Sports • sports.yahoo.com
Will the Columbus Blue Jackets Draft Oscar Hemming?

The Columbus Blue Jackets have the 14th overall pick in the 2026 NHL Draft. There are debates about whether or […]

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Jun 23 • 10:29 AM EDT • Sports • sports.yahoo.com
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Why Healthy People Often Become The Problem In Unhealthy Systems

Whether in families, workplaces, or friendships, the person who challenges dysfunctional norms is often blamed for disrupting the status quo.

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Jun 23 • 8:15 AM EDT • Health • forbes.com
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ANALYSIS: Fear not Britain, the EU doesn't agree on you rejoining either

Brussels heavyweights are clashing over whether Brexit can be reversed and on what terms

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Jun 22 • 10:00 PM EDT • Politics • euractiv.com
A common vitamin could help fight one of the deadliest brain cancers

A clinical trial is exploring whether high doses of vitamin B3 could give patients with glioblastoma a better chance against the aggressive brain cancer. Scientists found that niacin may help revive immune cells that tumors shut down, allowing them to attack cancer more effectively. Early results have been promising, with patients showing significantly better progression-free survival than expected.

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Jun 22 • 8:00 AM EDT • Science • sciencedaily.com