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World Cup 2026: USMNT stunned by Türkiye in stoppage time, losing perfect group stage run
4 Takeaways From USA's Last-Second World Cup Loss To Türkiye
So much for a perfect group stage. But the USA can now turn its attention toward the knockout stages.
UFC Baku early weigh ins results
Ultimate Fighting Championship (UFC) will stage its early and official weigh ins at 9 a.m. local time for this weekend’s UFC Baku mixed martial arts (MMA) event on Paramount+. Unfortunately for stateside fight fans, Baku is eight hours ahead of Eastern Standard Time, so most of us will be asleep by the time the first […]
Twin City Entertainment collaboration to host the Carol Burrnett Show in West Monroe June 27th
WEST MONROE, La. (KTVE/KARD) — Residents in the West Monroe area will have the chance to enjoy a night of laughter later this week as a live stage production inspired by The Carol Burnett Sho…
World Cup 2026: Christian Pulisic won't start for USMNT's group stage finale against Türkiye
Lionel Richie postpones concerts after falling ill during tour opener
Lionel Richie is pausing his return to the stage after abruptly falling ill during the opening of his new tour.
All the songs on Ariana Grande's Eternal Sunshine Tour
OAKLAND, Calif. – It's been six years since Ariana Grande’s last tour, and her yellow brick road has led her back to the stage.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Lionel Richie takes ill, cuts opening concert of tour short
The Rock & Roll Hall of Famer, who is 77, told his 10,000 fans he was feeling dizzy but performed for nearly an hour before leaving the stage.
Lionel Richie reportedly hospitalized after medical incident forced concert to end early
Lionel Richie has reportedly been hospitalized after a medical incident on stage forced him to sit down to sing a song on the opening night of his tour with Earth, Wind & Fire.
Embodying the Moment: Paloma Elsesser On Beauty, Bodies and Business
The model and muse explained her supermodel origin story and her plans for her next act onstage at The Business of Beauty Global Forum.
Rush CEO to step down, take health equity mission to national stage
Dr. Omar Lateef said he is handing off a health system at the top of its game and expects healthcare leaders from around the nation will be clamoring to fill the role.
🇺🇸 Y! Sports AM: Why not U.S.?
The USMNT, who play their final group stage match tonight, have given fans reason to believe in their status as contenders.
Lionel Richie falls sick, abruptly ends All Night Long tour opener
Lionel Richie abruptly cut his Minnesota concert tour opener short after "feeling dizzy" on stage.
How should European scientists respond to the US AI kill switch?
Earlier in June, Europe’s worst fears of technological dependence were confirmed when the White House ordered the AI firm Anthropic to stop non-US citizens using its leading models. This kill-switch moment crystalised anxieties in Brussels that the continent, lagging the US on the creation of leading-edge AI models, is now a technological of vassal of Washington. The shock has specific implications for European scientists and universities. Some governments are now worried that with AI being integrated into labs, Donald Trump now has his finger hovering over an off switch for European science. “Having restrictions on this tool, it can have an impact on our own research,” said France’s research minister, Philippe Baptiste, at the VivaTech conference in Paris on June 18.Baptiste, himself a former academic, said that colleagues in mathematics had recently warned him they were now cut off from leading-edge US models, risking their work. “This model is not available anymore now because of the US restriction, and for the first time this had an impact on mathematics,” a field where large language models (LLMs) are making a significant contribution, said Baptiste. So, should European scientists avoid relying on US models in the future? Or would this be a self-harming overreaction? And how is AI being used in science, anyway? What happened?On June 12, it emerged that Washington, citing cybersecurity concerns, had ordered Anthropic to stop non-US citizens using two models: Claude Mythos 5, and Claude Fable 5, a version of Mythos but with guardrails to prevent abuse. Anthropic said Washington’s concerns were overblown. But forced to follow the order, yet with no way to check who was using the models, the company suddenly shut down access for everyone, US citizens included. There’s still no agreement on how to restore broad access. But last week, Bloomberg reported that select US companies, and the US government, still had access to Mythos despite the ban, but the EU’s cybersecurity agency Enisa had been shut out. Class division of researchersIn the longer term, access outside the US should be restored, said Marcel Salathé, co-director of the AI centre at the Federal Polytechnic School of Lausanne (EPFL), because a permanent restriction would be financially ruinous to US AI firms. “Even Trump will eventually budge to economic pressure,” he said.However, US AI firms might end up operating rather like banks, doing due diligence on users of their leading-edge AI models, he went on.European scientists are unlikely to fall foul of such checks, he said. But having a Chinese postgraduate in their lab, or doing a type of research the US disapproved of, could potentially result in access being denied. “It will create a sort of class division of researchers,” he said. More than frontier modelsHowever, successfully deploying AI in science is about far more than just having access to leading LLMs such as Mythos.Instead, many science-specific tools, most famously Alphafold, which predicts protein folding structures, require “far less” computing power to train than frontier models, well within the capabilities of European supercomputers, according to a recent analysis by the Arq Foundation, a Brussel-based AI think tank. Instead, tools such as Alphafold are possible because certain fields, like protein folding, weather prediction or astronomy, have large, clean, standardised datasets that can be used to train predictive models. Rather than compute, “data is the central constraint for AI for science,” the report says. For example, a less powerful physics model trained on CERN’s data “will be more valuable than the best model without certain data,” said Bengüsu Özcan, author of the report. European advantage?Europe could therefore steal a march by using its scientific data and infrastructure to create models US digital giants cannot. “They might actually match or go even beyond what these big [US] companies are doing,” said Özcan.Indeed, some European start-ups hope to create automated testing labs to create the kind of standardised data that could speed up the discovery of new materials. Materials scientists say there’s currently too little data to train models. AI scientistsHowever, even if the bottleneck for AI in science is often data, rather than compute, being at the mercy of the US for LLM access could still become a problem for European scientists. A new class of “AI scientists” based on leading LLMs is also emerging, Özcan’s report says.Unlike domain-specific tools like Alphafold, these try to automate day-to-day scientific work, by providing an overarching tool that coordinates specific models to synthesise existing literature, generate hypotheses or run analysis of data. The problem for Europe, however, is that these tools are sometimes based on US leading models. Google Deepmind’s AI Co-Scientist, for example, is built on Google’s Gemini LLM. Systematic failureThese scientific automation tools are still in their early stages, and still exhibit “systematic failures on scientific tasks,” Özcan’s report says. One of the problems is that the messy, day-to-day process of scientific discovery is largely not documented, meaning LLMs don’t have a good source of data to learn how scientists actually work. Meanwhile, some tasks, such as literature synthesis, don’t typically require access to leading edge models.However, the performance of AI scientific assistants could improve as companies such as Google pour resources into developing them. Rely on US“Unfortunately, for scientific assistants, there is not much we can do right now except rely on US frontier AI,” said Antoine Bosselut, a natural language processing expert based at EPFL. Chinese-built open models, which can run on local computers, lessening the risk of a shutdown, are touted as one alternative to US dependence. There’s also Mistral, once seen as Europe’s main AI hope, but the Paris-based company has seen its recent models fall behind in performance. But the Chinese alternatives are generally not as capable as US frontier AI models, said Bosselut, unless paired with fiddly, custom tools that allows them to act as independent agents. “Most scientists do not have the time,” he said. Don’t jump ship yetAlthough the kill switch moment is seen a warning shot for European scientists, it doesn’t mean labs should abandon US AI tools immediately. “I do not think the right response is simply to abandon US-based models and systems under the banner of sovereignty or independence,” said Mattias Björnmalm, secretary general of the Cesaer university association. “That would be an overreaction.”Related articlesEuropean sovereignty in AI requires ‘ugly trade-offs,’ say experts Robotic lab start-up makes case for €500M EU-funded materials testing facilityAI in science: is it useful? Instead, European researchers need to ask themselves whether they’re becoming dependent on technology that could be turned off in Washington, said Özcan. “They might not see this today, but they should really start asking this question,” she said. European researchers need a plan B, said Salathé. “I would recommend to every researcher, very proactively explore alternatives.”Own toolsIn addition, Björnmalm and others want European research institutions to develop their own scientific AI tools.Instead of signing AI deals with US digital giants, European universities should be using this money to create their own models, which may end up being superior for research, said Sabine Leonelli, an expert on the use of AI in science at the Technical University of Munich. “Universities in Europe seem to be happy to sign commercial contracts with US companies on the assumption [their AI tools] are better,” she said. But US frontier LLMs are typically opaque, and have been developed without independent scientific input, she said. “This is not good enough for science.”Last year, Swiss researchers released Apertus, an LLM designed to be completely transparent, from its development methods to its training data. The idea is that this makes scientific tools built on top of the model far more reproducible than with closed, commercial alternatives.“Europe needs more of this: serious capacity-building that gives researchers, universities and companies credible options,” said Björnmalm.
Playing soccer can score major goals for heart and brain health
Seattle, June 25, 2026 — As the global soccer championship run by the Fédération Internationale de Football Association (FIFA) plays out on stages across the world this summer, catching a fever for football (as soccer is known outside the U.S.) may...
Star Fox Routes Walkthrough And Alternate Routes Map For Every Stage
Plan-et your way ahead
Folarin Balogun and USMNT Transfer Updates
Hosts Tamerra Griffin and James McNicholas break down a massive six-match World Cup slate as group stages reach their climax. Soccer insider David Ornstein joins the show to discuss the escalating transfer market buzz surrounding USMNT star Folarin Balogun and Tottenham’s Lucas Bergvall. Plus, the team highlights The Athletic’s interactive World Cup Tracker with Jay Harris to map out the complicated qualification pathways for Group A, B, and C. Can the USMNT line up a favorable Round of 32 matchup? Senior Editor Hannah Vanbiber also dives into the debate surrounding Jeremy Doku’s...
Australia Faces a Trumpian Turn in Politics
Pauline Hanson’s far right One Nation is no longer an outsider on the political stage.
⚽ Keep it rolling
Tonight, the U.S. play its final group stage match.
Trump news at a glance: US president holds a rare bipartisan bill hostage
Trump says he’ll sign housing bill aimed at lowering costs only after Senate passes restrictive voting measure – key US politics stories from Wednesday 24 June at a glance
Hong Kong Science Fair marks five years of youth innovation
As the city’s flagship I&T education event returns, it continues to connect classroom learning with real-world invention and open doors to the international stage
4 Takeaways From Canada's Group-Stage Finale Loss To Switzerland
Both teams advance to the World Cup knockout round, but one clearly looks better than the other.
Oprah reveals Whitney Houston moment she begged audience not to share
Oprah Winfrey has revealed she "begged" audience members not to release photos of Whitney Houston falling off the stage at her show in 2009.
The Teenage Mutant Ninja Turtles are coming to life on stage. See when
The Teenage Mutant Ninja Turtles will come to town life in a tour for 'Teenage Mutant Ninja Turtles Live on Stage!'.
Mexico XI vs Czechia – Predicted lineup and team news
Mexico conclude their 2026 World Cup group stage campaign with a clash against Czechia at the Estadio Azteca in the early hours of Thursday morning.The co-hosts have won back-to-back games against Sou...
The Best Politics Are Local
As America turns 250, the celebrations in Washington and Philadelphia will naturally take center stage. But equally important is what goes on in every town hall, county seat and school board, where the triumph of...
Taylor Swift shocks crowd with surprise 'Love Story' performance, flashes ring at fiancé Travis Kelce's event
Swift joined country superstar Lainey Wilson on stage at Kelce's Tight Ends & Friends charity concert in Tennessee.
Crooked Letter Sports: With the College World Series and U.S. Open behind us, World Cup soccer takes center stage
Today’s show features wrap-ups of the CWS and U.S. Open, with veteran Mississippi soccer coach Dean Joseph joining the pod to discuss how the tournament is shaping up and the wizardry of Lionel Messi.
Movies and TV shows casting across the US
Backstage compiled a list of movies and TV shows casting across the US.
MumFest unveils entertainment schedule for community stage
NEW BERN, Craven County — Performers will take the Howard Matthews Memorial Stage during MumFest 2026.The stage will feature performances every hour throughout
Kenny Chesney explains why he keeps politics offstage
Kenny Chesney opens up about politics, celebrity influence and why he keeps his concerts focused on music.
4 Takeaways From England-Ghana Scoreless Stalemate At World Cup
A gritty draw for Ghana over an England team that was frustrated all day sets up a thrilling finale in group stage play.
Octoberfest adds country stage for 2026; see the full lineup
Organizers of the annual party in downtown Appleton announced the entertainment lineup for the 2026 event.
Polymarket allegedly faked trades. Chances are slim Trump admin investigates, says sports-betting attorney
A recent Wall Street Journal investigation found that the prediction market hired influencers to stage fake trades as part of its marketing campaign to attract U.S. users.
The Carriage House at Paper Mill Playhouse Launches Summer 2026 Entertainment Series
(MILLBURN, NJ) -- The F.M. Kirby Carriage House at Paper Mill Playhouse announces its inaugural Summer Entertainment Series, introducing acclaimed Broadway and cabaret artists Evan Tyrone Martin (New York City Center's The Wild Party) and Annie Hägg (Giant) to lead an expanded lineup of live entertainment throughout July and August at the newly refurbished restaurant and event space.
Madison music venues take center stage at High Noon Saloon event
MADISON, Wis. — Madison’s rich live music history will take center stage Tuesday night at a special event at the High Noon Saloon.
Health officials launch clinical trial reforms to counter China threat
The Food and Drug Administration (FDA) on Monday launched a new initiative to speed up early-stage clinical trials as part of an effort to reduce development timelines and reverse a growing trend o…
Federal health agencies unveil plan to speed up phase 1 clinical trials by 6 to 12 months
As the biotech world flocks to San Diego today for the BIO International Convention, the Department of Health and Human Services has provided plenty of conversation fodder with the announcement of | As the biotech world flocks to San Diego today for the BIO International Convention, the Department of Health and Human Services has provided plenty of conversation fodder with the announcement of a series of efforts to regain ground on China’s surging early-stage clinical development capabilities.
FDA to launch pilot program to speed up early-stage clinical trials
Federal health officials aim to speed up drug development and better compete with China.
Breaking Business News: AbbVie To Acquire Apogee Therapeutics
AbbVie is set to acquire Apogee Therapeutics and its pipeline of multiple clinical-stage candidates in development across inflammatory and immunological diseases, including its lead asset, zumilokibart (APG777), a subcutaneous half-life extended monoclonal antibody targeting interleukin (IL)-13 in atopic dermatitis (AD). Under the terms of the transaction, AbbVie will acquire all outstanding shares of Apogee for $135.11 per share in cash. […]
‘Problem-solving, innovation, and meaningful impact’: Jessica Fuertes-De Arcos’ multi-disciplinary Cyclone Engineering experience
Jessica Fuertes-De Arcos walked across the stage at the Iowa State University commencement ceremony to accept her bachelor’s degree in chemical engineering in May of 2026.
Rod Stewart says he 'nearly fainted' during Utah concert
Rod Stewart is recovering after nearly fainting onstage over the weekend.
Asheville film event to spotlight mental health, raise funds for counseling services
Filmmakers from across the Carolinas will be taking stage in Asheville as a regional film event aims to spark conversation about mental health.
U.S. and FIFA have room for improvement as hosts for the World Cup
At this World Cup, Iran has been subjected to shifting travel restrictions and uncertainty unlike the other 47 teams.
AP Decision Notes: What to expect in New York’s state primary
Democratic nomination contests for New York’s seats in the closely divided U.S. House take center stage Tuesday in a state primary
World Cup 2026: Who's facing who in the last 32? Every potential fixture in the knockout stages!
Who could England and Scotland face in the last 32? How are the routes to the final shaping up? Keep tabs on the potential knockout stage line up with our live World Cup bracket
Rock Legend Rod Stewart Needs Oxygen On Stage In Frightening Moment Caught On Video
The 81-year-old was able to continue the show... but he did need to take a seat.
📸 Hossam Abdelmaguid suffers a nasty knock against New Zealand
Hossam Abdelmaguid suffered a shocking blow in the final minutes of Egypt vs. New Zealand, on the second matchday of the World Cup group stage. It happened during an aerial challenge for the ball, w...
From Rocafonda to rock star: The rise of Lamine Yamal
Braces-wearing teen phenom Lamine Yamal is ready to take center stage in the 2026 World Cup.
Young performers to bring 'The Jungle Book' to life in Temple
The jungle will come alive on stage next Saturday as dozens of young performers present Disney's "The Jungle Book KIDS" at the Cultural Activities Center, showcasing a week of intensive
The Political Education of Mark Carney
On the world stage, Canada's prime minister is a statesman. In Ottawa, he is a ward boss.
Rock Legend, 81, Suffers Frightening Onstage Health Scare
The “Forever Young” singer had to stop the show to take breaths from an oxygen tank.
🚨Official: Mexico climb the FIFA rankings
The Mexico national team is enjoying a strong moment at the World Cup on home soil, as in addition to being close to earning nine points in the group stage for the first time, it would also set a new ...
Germany and Ivory Coast name sides for Cup clash
The national teams of Germany and Ivory Coast have announced their lineups for this Saturday’s (20th) match in the second round of the World Cup group stage.The clash in Toronto, Canada, pits two te...
Hurricanes fans jam into downtown Raleigh for team's Stanley Cup parade
Thousands of fans arrived hours early to line sidewalks for the team’s victory parade or packed in near the rally stage.
Kid-run businesses will take center stage at the Acton Norman Children’s Business Fair
For one day only, kid-run businesses will take center stage at the Acton Norman Children’s Business Fair, allowing young entrepreneurs to showcase their creativity, products, and business skills.
Massive N.J. country music festival gets strangely emotional as 2 stars cry on stage |Review
Barefoot Country Music Festival was full of surprises this year
World Cup 2026: Curacao's trailblazer doctor on football's big stage
Dr Suzanne Huurman is head of medical staff for Curacao's national men's side - the World Cup's smallest ever team by population and size.
World Cup brings political issues to the surface: 5 takeaways
The first week of the FIFA World Cup has been underscored by tensions over geopolitics, U.S. immigration policy and dramatic group stage action that is priming viewers around the world for what pro…
🎥 World Cup highlights: What drama, Paraguay knock Turkey out
You couldn’t make this up! Having gone into the World Cup as something of a dark horse, Turkey already has to bow out after just two group-stage matches. The 0–1 loss to Paraguay sealed their earl...
Turkey’s World Cup was a gigantic disappointment
A very talented generation failed at the biggest stage
Ireland's Doris will get new injury 'checked out'
Leinster captain Caelan Doris will get a new injury checked out after being forced off in the early stages of his side's 36-7 United Rugby Championship final win over the Bulls.
WATCH: Would-be second-term President Biden left searching for family on stage after Obama Center opening
Biden sparked an awkward moment at Obama's presidential library dedication, drifting back toward the stage and shouting for his granddaughter.
A Coalition of Color Is Transforming Health Equity in Massachusetts
The Health Equity Compact is bringing together Massachusetts leaders of color to advance policy changes that improve health equity statewide.
For Vance, Iran talks could shape political rise
U.S. Vice President JD Vance is poised to take on his biggest role yet on the international stage as President Donald Trump's chief negotiator to end the three-month war with Iran, a moment that could shape Vance’s prospects as a White House successor.
Edenville General Store looks to expand entertainment offerings
Edenville General Store is looking to increase live music and other entertainment offerings with the addition of a new mobile outdoor stage. The approximately 2...
K-Stage Festival to give Hong Kong a dose of Korean culture beyond BTS
Starting June 25, the festival will mix new and old in stage shows designed to show a different side of South Korea’s eclectic culture.
Second Annual Cenevo Survey of Life Science Professionals Reveals Future of AI in Modern Labs
AI adoption is widespread across life sciences laboratories, but it is still mostly in the experimental stage, with only 5 percent using AI agents in production, according to Cenevo's second annual survey.
Second Annual Cenevo Survey of Life Science Professionals Reveals Future of AI in Modern Labs
/PRNewswire/ -- AI adoption is widespread across life sciences laboratories, but it is still mostly in the experimental stage, with only 5 percent using AI...
Bleachers take the stage at CMAC this weekend
Bleachers perform at CMAC this Saturday. Here is what you need to know about tickets, parking, and the venue's bag policy.
📸 2026 World Cup: our team of the opening round
Some big names.The first matchday of the 2026 World Cup group stage wrapped up this Thursday morning with Colombia’s 3-1 win over Uzbekistan. And this afternoon at 6 p.m., the second matchday gets ...
India (W) play Uruguay in hockey Nations Cup, Macau Open, Boxing WC Stage 2 continue: Indian Sports LIVE, June 18
Here are all the updates from Indian sports on June 18, 2026.
Gurman: Apple AirPods with built-in camera may arrive in late 2027
The AirPods are said to debut alongside the second-gen iPhone foldable. Back in May, a report claimed that Apple had entered the final stages of...
'Top Gear' star Jeremy Clarkson reveals 'aggressive' cancer diagnosis after health scares
Jeremy Clarkson reveals he is battling aggressive but early-stage prostate cancer in the final two episodes of "Clarkson's Farm" season five.
ENTERTAINMENT: UCA show turns Conway into Sherwood Forest
The University of Central Arkansas Summer Theatre stages “Ken Ludwig’s Sherwood: The Adventures of Robin Hood,” Ludwig’s “theatrical reimagining” of the tale of the legendary outlaw and his Merry Men.
ENTERTAINMENT: UCA show turns Conway into Sherwood Forest
The University of Central Arkansas Summer Theatre stages “Ken Ludwig’s Sherwood: The Adventures of Robin Hood,” Ludwig’s “theatrical reimagining” of the tale of the legendary outlaw and his Merry Men.
Fifteen Siena Student-Athletes Earn Arthur Ashe Jr. Sports Scholar Recognition
Siena Athletics was well represented on the national stage as 15 student-athletes were named 2026 Arthur Ashe Jr. Sports Scholars by Diverse: Issues in Higher Education, with honorees representing five different athletic programs.
Austria make World Cup return with win over debutants Jordan
Veteran Marko Arnautović scored in his World Cup debut as Austria made their return to the big stage with a 3-1 victory in their tournament opener on Tuesday. The Austrians are making their first World Cup appearance since 1998, while Jordan have qualified for the competition for the first time in their history.
Share your talent at Open Mic Mondays
Do you enjoy singing and performing for an audience? Take the stage at the Waynesville American Legion's Open Mic Mondays from 7-9 p.m. every Monday in June.
Intel takes a major step toward turning around a business that’s bleeding cash
Intel’s new manufacturing process has entered a stage that signals the company is confident in its ability to bring on external customers, analysts say.
European Union Releases Draft Sustainability Reporting Standards For U.S. Businesses
Europe's financial regulator is in the final stages of developing sustainability reporting standards for non-EU based businesses, with a vote on June 18.
U of A food science students advance to IFTSA College Bowl, a national trivia competition in Chicago
University of Arkansas students are putting local food science talent on the map, recently winning a high-stakes regional trivia showdown and advancing to the national stage next month, a press rel…
Turkey's Erdogan Is Running Out of Tricks
"The latest maneuvers of President Recep Tayyip Erdogan of Turkey signal that he has no plans to quietly exit the political stage," writes Ian Bremmer.
‘Paddington’ stage musical to pack its marmalade sandwiches and travel to Broadway
Paddington Bear is heading to Broadway with “Paddington The Musical” set to play at the Al Hirschfeld Theatre in March.
Hong Kong Science Park, SenseTime partner to build home-grown AI data centre
Project to be built in three stages, targeting 40,000 petaflops of computing power by 2030 to drive sector’s industrialisation.
These forward-looking, early-stage businesses are already standing out
The World Changing Ideas On the Rise honorees are tackling issues like accessibility, climate change, and more.
'Clarke to drop Shankland for Christie or McLean'
If we rewind 36 years to 16 June 1990 and the Italian city of Genoa, Stuart McCall was busy scoring to help Scotland secure a 2-1 win over Sweden. The former midfielder jokes that he "was always deadly from a yard out" and ultimately that victory wasn't enough to ensure Scotland progressed to the knock-out stage, but up until this weekend, it was their last win at a World Cup finals. Now the 62 year-old is assistant to Paul Heckingbottom at Preston North End, but he's also enjoying absorbing all the action from the United States, Canada and Mexico.
Football upstages politics as Iranians rally behind their team at World Cup
In opener against New Zealand in Los Angeles, Iran's Team Melli gets cheers from thousands of anti-regime supporters.
Belpre Homecoming reveals entertainment lineup for 94th year
BELPRE – Local artists and tribute acts will provide the entertainment at the 2026 Belpre Homecoming in August for the festival’s 94th year. The four-day event kicks off Thursday, Aug. 6, in Civitan Park. Local band Insured Sound takes the stage at 8 p.m., sponsored by the Belpre Woman’s Club. Performing for over 50 years, […]
Belpre Homecoming reveals entertainment lineup for 94th year
BELPRE – Local artists and tribute acts will provide the entertainment at the 2026 Belpre Homecoming in August for the festival’s 94th year. The four-day event kicks off Thursday, Aug. 6, in Civitan Park. Local band Insured Sound takes the stage at 8 p.m., sponsored by the Belpre Woman’s Club. Performing for over 50 years, […]
Katie Thurston Delays Biopsy, New Treatment for Stage 4 Breast Cancer for 'Mental Health Reasons’: ‘I Need a Break’
Katie Thurston has been open about her fear of needles and the emotional toll of her stage 4 breast cancer journey. The ‘Bachelorette’ alum said she’s now pushing back a biopsy and new treatment to prioritize her mental health.
Millions take calcium and vitamin D for stronger bones. A major review finds little benefit
For years, calcium and vitamin D supplements have been promoted as a simple way for older adults to protect their bones and prevent falls. But a massive review of nearly 154,000 people found that calcium, vitamin D, or a combination of both provided little to no meaningful protection against fractures or falls for most older adults.
Tottenham join race for Moroccan wonderkid after World Cup debut
Saturday afternoon saw the 2026 FIFA World Cup usher in one of the names for the future into the global game, Morocco's Ayyoub Buaddi, with the wonderkid playing a large part of his national team's draw against perennial powerhouse Brazil. It was just more than just a debut, as it showed that Bouaddi can perform on the global stage against some of the best players in the world, emboldening the interest that teams had in him following his stellar campaign with Lille in Ligue 1, winning out on 49 tackles and recording 33 interceptions last season for the French outfit. All in all, the Moroccan wonderkid has been looked at and is being closely followed by the likes of Arsenal, Liverpool, and Paris-Saint Germain, amongst others, but according to a recent report, yet another English club is pursuing the 18-year-old.
HMNC Brain Health announces $50 million first closing of Series B financing and a strategic partnership with MEDICE
Financing will accelerate the development of HMNC’s neurosciences portfolio, including Phase 3-readiness activities for Ketabon (KET01) and Nelivabon (BH-200)Agreement grants MEDICE exclusive European commercialization rights for KET01, with tiered double-digit royalties and significant milestone payments MUNICH, Germany, June 15, 2026 – HMNC Brain Health ("HMNC" or the "Company"), a clinical-stage neuroscience company, today announced the successful $50 million first closing of its Series B fin
Visitors' viral World Cup videos show what really makes America great
International soccer fans discovering the wonders of America, from spacious skies to chicken fried steak, is giving the U.S. a much-needed morale (and PR) boost.
Trump puts himself at center of birthday spectacle
Trump marked his 80th birthday with a UFC fight staged on White House grounds — a spectacle that underscored how he has sought to turn sports, historically an escape from politics, into another front in America's divisions.
Zac Brown's UFC performance was about 'patriotism, not politics'
Before he took the stage to sing the national anthem outside the White House to kick off UFC Freedom 250, Zac Brown stood firm despite blowback.
Why Marketing Feels Harder as Your Business Grows by Nathan Tayloe
At some point, most growing businesses hit the same moment. What used to feel straightforward starts to feel more complicated. Marketing takes more effort. Results feel less predictable. What once worked consistently begins delivering mixed outcomes. It is easy to assume something is broken. In many cases, nothing is. The business has simply reached a different stage. What Worked Before Starts to Lose Its Edge Early on, growth is often driven by a few things working well at the same time: Referrals are strong The value of the offering is clear The team is aligned Decisions are made quickly Marketing, in that stage, tends to feel easier because the business itself is easier to understand. As the company grows, that simplicity fades. The audience expands. Services evolve. New people join the team. More channels are added. More decisions are made across more touchpoints. Marketing is no longer communicating one clear story. It is trying to represent a more complex business. Complexity Creates Friction That added complexity does not always show up immediately. It builds over time. Messaging starts to drift. Different parts of the business describe what they do in slightly different ways. The website no longer reflects how the company actually operates. Sales conversations evolve faster than the brand. At the same time, more activity is introduced to try to keep growth moving: New campaigns More content Additional platforms More tools and reporting The volume increases. The clarity does not always keep pace. That is when marketing starts to feel harder. It’s Not a Lack of Effort Most teams respond to this stage by doing more. More output More meetings More adjustments More experimentation That effort is not misplaced. It is often pointed in the wrong direction. When the underlying issue is a lack of alignment, more activity tends to create more noise. Results become harder to interpret. Decisions take longer. Progress feels inconsistent. From the outside, everything looks active. From the inside, it feels less certain. The Real Shift As businesses grow, marketing becomes less about execution and more about alignment. The companies that navigate this transition well tend to refocus on a few fundamentals: A clearly defined audience A strong, consistent position in the market Messaging that reflects how the business actually operates Alignment between leadership, marketing, and sales When those elements are in place, execution becomes more effective again. Marketing does not necessarily become easier, but it becomes more consistent. A Different Kind of Discipline Growth introduces more opportunity, but it also demands more discipline. What worked when the business was smaller often cannot be scaled without adjustment. The systems, messaging, and decision-making that once felt intuitive need to become more intentional. That is not a sign of failure. It is a normal part of growth. Marketing feels harder because the business has become more complex. The solution is not to outwork that complexity. It is to bring clarity to it. The companies that do that well tend to regain momentum quickly. Those who do not often stay busy without seeing the same level of progress. — Learn more about how we help organizations align strategy, brand, and execution. Visit tayloegray.com, or reach out directly at nathan@tayloegray.com.
World Cup 2026: Every goal from the Netherlands-Japan thriller
Sunday’s group stage match between the Netherlands and Japan lived up to the hype. Here is every goal from that thriller