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Atletico Madrid add Inter defender to summer transfer shortlist

Atletico Madrid are set for another busy summer transfer window, with several areas of Diego Simeone’s squad needing to be addressed. One of those is left-back, which has been a position of concern ...

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Mar 29 • 5:30 AM EDT • Sports • sports.yahoo.com
Scientists say the evidence is clear: E-cigarettes beat patches and gum in helping smokers quit

Nicotine e-cigarettes may be one of the most effective tools yet for quitting smoking, according to a sweeping review of global research. By analyzing findings from 14 major reviews spanning nearly a decade, researchers found consistent, high-quality evidence showing that nicotine vapes outperform traditional methods like patches, gum, and even behavioral support. While some lower-quality studies produced mixed results, the strongest data clearly favored nicotine e-cigarettes.

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Mar 28 • 8:00 PM EDT • Science • sciencedaily.com
Radiation levels in Spanish city surprise scientists

Study reveals that Melilla has lower-than-expected radiation levels, surprising scientists after 15 years of detailed analysis

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Mar 28 • 5:32 PM EDT • Science • earth.com
Big League Chew Builds 2026 Ambassador Roster Around Baseball, Softball, and Entertainment Culture

Key Takeaways Big League Chew names five brand ambassadors for 2026, spanning youth baseball, professional softball, women's baseball, and entertainment Mo'ne Davis, the first girl to win and pitch a shutout in the Little League World Series, headlines the class Jocelyn Alo, the NCAA Divis

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Mar 28 • 10:34 AM EDT • Entertainment • youthsportsbusinessreport.com
Impossible Science Live! with World Champion of Magic Jason Latimer

Impossible Science Live! with World Champion of Magic Jason Latimer From bending light with physics, to shaping water with chemistry and walking through solid glass with engineering, World Champion of Magic Jason Latimer’s mind-blowing live show delivers an inspiring message of how “The right question changes everything.” Impossible Science LIVE! expands on Jason Latimer’s inspiring TED Talk “ Seeing Beyond the Illusion of Knowledge ” with family-friendly, mind-blowing illusion entertainment. Uniting his favorite illusions from his illustrious career, Latimer reveals the secret to his magic is not special powers but simply a pursuit of challenging the impossible with curiosity. During your museum visit from April 7-11, 2026, drop into the auditorium for one of Latimer’s shows throughout the day. Shows are included with your Spring Break admission and FREE for museum members. Add a membership to your cart for free Spring Break admission! Available showtimes: 10:30 a.m., 11:30 a.m., 1 p.m., 2 p.m. daily, with a 3:30 p.m. show on Saturday, April 11. Open seating; first come, first seated. About Jason Latimer: Jason Latimer has been featured on television around the world as both a scientist and magician. While Latimer is both a curator of the iconic Fleet Museum in San Diego, CA, and a World Champion Magician his network specials, TV series, and appearances span the globe. Jason has been featured as a science host on the Science Channel, Roku, Amazon, and as a magician on the Syfy Channel, History, BBC ONE, and Japan’s NHK. In 2021, SONY partnered with Latimer to bring his unique blend of science and magic to online and to PBS to assist with distance learning. Impossible Science’s growth has been exponential ever since, garnering over a hundred million views and multiple streaming awards as an educational series.

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Mar 27 • 4:55 PM EDT • Science • iloveny.com
Giant golden spiders could spread this summer, experts downplay health risk

Joro spiders, which have 4-inch leg spans, are spreading across the eastern U.S., and Penn State says they could reach Pennsylvania. Experts say not to panic, as they're shy and rarely bite.

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Mar 27 • 4:09 PM EDT • Health • foxnews.com
BERRY: Nebraska’s season ends in heartbreak fashion

After a memorable season spanning four months and 28 days, highlighted by 28 wins, only seven losses, broken records, flu games and infinite memories, Nebraska’s historic 2025-26 season ended in Houston on Thursday night.

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Mar 27 • 2:15 PM EDT • Sports • dailynebraskan.com
Ashley Benson Signs With Strand Entertainment

EXCLUSIVE: Strand Entertainment has signed Ashley Benson, an actress and producer whose work spans studio features, independent film, and television, for management. Benson was most recently seen star...

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Mar 27 • 12:03 PM EDT • Entertainment • nz.news.yahoo.com
Dartmouth Health adds 26 new providers from various disciplines across health system

Providers span 13 healthcare disciplines and practices across nine Dartmouth Health locations

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Mar 27 • 8:00 AM EDT • Health • dartmouth-hitchcock.org
2025 American Association for the Advancement of Science (AAAS) Fellow

Department Chair, Professor Alexander Spokoyny has been selected as a 2025 Fellow of the American Association for the Advancement of Science (AAAS) in recognition of his distinguished contributions in main group and organometallic chemistry and academic community engagement and leadership. AAAS is the world’s largest general-scientific society and publisher of the journal Science. Spokoyny is among the 449 scientists, engineers, and innovators spanning 24 scientific disciplines who are being recognized for their scientifically and socially distinguished achievements. Four of the new fellows are UCLA faculty members. The new Fellows will be celebrated in Washington, D.C., in late May 2026. Read more about the new AAAS Fellows here. AAAS Fellows in the UCLA Department of Chemistry & Biochemistry are Professors Kendall Houk (1988), Paul Weiss (1999), Richard Kaner (2000), David Eisenberg and Todd Yeates (2001), Juli Feigon (2002), Miguel Garcia-Garibay and Steven Clarke (2007), Heather Maynard, Carla Koehler, Xiangfeng Duan and Neil Garg (2018), Paula Diaconescu and Thomas Mason (2019), Joseph Loo (2021), and Yi Tang (2022). Penny Jennings, UCLA Department of Chemistry & Biochemistry, penjen@g.ucla.edu.

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Mar 26 • 11:05 AM EDT • Science • chemistry.ucla.edu
Ten Johns Hopkins researchers named American Association for the Advancement of Science Fellows

The 2025 class of American Association for the Advancement of Science fellows includes 449 scientists, engineers, and innovators spanning 24 scientific disciplines who are being recognized for their scientifically and socially distinguished achievements

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Mar 26 • 10:13 AM EDT • Science • hub.jhu.edu
Good Morning, Nashville! Talking Immigration Data Politics at Vanderbilt University

After a busy day on Capitol Hill yesterday, I landed in Nashville, Tennessee, last night for an exciting two days on campus at Vanderbilt University. Carwil Bjork-James, an anthropologist whose creative use of database construction to support critical scholarship resonates strongly with my own work, generously invited me to give a talk today about the politics of immigration data and to join a Wikipedia edit-a-thon tomorrow on the topic of immigrant detention. I encourage you to check out Carwil’s database project “Ultimate Consequences” about political deaths in Bolivia after 1982, and his book The Sovereign Street: Making Revolution in Urban Bolivia. My talk today is titled “Untangling the Messy Politics of Immigrant Detention Data.” I’ll focus on how immigrant detention data (not just detention centers themselves) become sites of controversy—from the collection and classification choices that shape what we can know, to the strategic withholding and distortion of data for political ends. Drawing on research spanning multiple administrations, I’ll trace how current data controversies in the second Trump administration connect to long-standing tensions in how we measure, interpret, and communicate about immigration. My goal is to move beyond simple partisan narratives and offer a practical guide for anyone working with immigration data to explore both the pitfalls to avoid and the creative opportunities for more transparent, rigorous public communication about immigration realities. If you are on campus, please stop by. Tomorrow I will join Carwil and Vanderbilt students for a Wikipedia Edit-a-Thon to edit and update Wikipedia entries related to immigrant detention with the latest robust information and data. This event is designed to orient participants into how to edit on Wikipedia, provide them with data-driven starter templates on detention facilities, and allow each person to produce an initial article on one element of the network of ICE facilities or one death in custody this year. The workshop is also a demonstration of how to use open data sources to build public knowledge—something I am deeply passionate about. Thank you to Vanderbilt University, the Spatial Histories series, and Carwil for hosting me. I would love to be a part of conversations and workshops related to immigration data on your campus. Students are really eager these days to have informed, critical, and data-driven explorations of our current immigration system. Reach out anytime if you want to discuss the possibility of bringing me to your campus. Subscribe

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Mar 26 • 7:55 AM EDT • Politics • austinkocher.substack.com
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ESPN earns industry-leading 63 Sports Emmy nominations

ESPN earned an industry-leading 63 nominations for the 47th Annual Sports Emmy Awards, as announced by the National Academy of Television Arts and Sciences today. The total marks ESPN’s 13th consecutive year leading the industry in Sports Emmy nominations. The nominations span content and accomplishments presented across ESPN platforms, including ESPN, ABC, ESPN+, ESPN Deportes and the ESPN App.

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Mar 25 • 1:14 PM EDT • Sports • espnpressroom.com
Partisan brawl in Virginia muddles Spanberger’s message of moderation

The congressional redistricting fight is tainting the governor’s image, one Democrat said: “This should be a flashing red light for Democrats everywhere.”

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Mar 25 • 5:00 AM EDT • Politics • washingtonpost.com
Poll: 1 in 3 Adults Are Turning to AI Chatbots for Health Information, Equaling the Share Who Use Social Media for Health

About a third (32%) of adults nationally say they have turned to artificial intelligence (AI) chatbots in the past year for health information, a new KFF Tracking Poll on Health Information and Trust finds. Most who turned to AI for health information say they were in search of quick and immediate advice, though challenges affording and accessing health care also play a role, particularly for younger adults.

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Mar 25 • 5:00 AM EDT • Health • kff.org
Grifols Plans IPO of U.S. Biopharma Business

The Spanish pharmaceutical company is looking to raise money to bolster its balance sheet and fund investments.

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Mar 25 • 4:06 AM EDT • Business • wsj.com
Hasbro Entertainment Advances ‘The Game of Life’ Film at Amazon MGM Studios

The project adds to a growing slate of IP-driven content spanning film, TV, and streaming.

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Mar 24 • 8:09 PM EDT • Entertainment • toybook.com
Tone, Humor, and the Performative Aspect of Politics

Senators John Kennedy (R-LA) and Peter Welch (D-VT) joined C-SPAN "Ceasefire" host Dasha Burns to discuss the roles of tone and humor in politics.

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Mar 24 • 3:03 PM EDT • Politics • c-span.org
Carbonsphere launches for carbon science and net-zero solutions

Tsinghua University Press is pleased to announce the launch of Carbonsphere, a new open-access, peer-reviewed journal dedicated to carbon science, technology, and policy. Sponsored by Qinghai University and Tsinghua University and published by Tsinghua University Press, the journal creates a new interdisciplinary platform for research spanning natural systems, engineered systems, and human systems.

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Mar 24 • 8:00 AM EDT • Science • eurekalert.org
We disagreed on politics. We agreed on wine. That was enough.

At the Virginia Governor’s Cup Gala in Richmond earlier this month, a very dapper gentleman approached me and introduced himself. In his light-colored suit and bowtie, he looked very Southern in a classical sense, the sort of Virginia Gentleman you used to see south of the Rappahannock as recently as my college days. “I’m a longtime reader and fan of your writing, if not your politics,” he said. His comment was the proverbial iron fist in a velvet glove, simultaneously conveying praise and disapproval while establishing boundaries. Man, I wish we still discoursed like this instead of shouting bromides and insults to try and “own” our opponents with a funny meme and a furrowed brow. Subscribe “Well, we’ll always have wine to share together,” I said, and thanked him for his kind words. We clinked glasses, exchanged pleasantries about the delicious gold medal-winning wines being poured that evening, and went our separate ways. Our exchange reminded me that more unites us than divides us. Wine brings people together to share a meal and a few hours of joy despite our differences.1 That’s why I refer to the wine community — including readers and consumers — rather than the wine industry. Together, we are so much more than production, distribution and sales statistics. A few minutes later the evening’s awards ceremony began. Applause grew as the 12 winemakers who made the top-scoring wines for the Governor’s Case took the stage, including a loud cheer for Jonathan Wheeler of Trump Winery and his 2018 Blanc de Noir sparkling wine. All the winemakers on stage had reason to be proud, Wheeler perhaps more so. Trump Winery was the only winery to win six gold medals in the competition this year. (Wineries are limited to six entries.) Two of Wheeler’s ciders also won gold medals in a separate competition. When you cover the labels and take the sour taste of politics off your palate, the wines are pretty darn good.2 Then Gov. Abigail Spanberger, newly elected Democrat and Virginia’s first female governor, was introduced to great applause to announce which of the 12 wines had won the Governor’s Cup. She spoke for a few minutes about the importance of wine to Virginia’s economy and tourism and the international acclaim Virginia wine has received. Just two weeks earlier, she gave the Democrats’ response to Trump’s State of the Union speech, but this night wasn’t about politics. That didn’t stop several people in the crowd from speculating on the irony should she have to present the trophy to Trump Winery. In the end, Valley Road Vineyards was displayed on the screen behind Spanberger as the winning winery. Blue Bee Cidery in Richmond took top honors for that category. The crowd cheered a female governor presenting the state’s highest trophy to a female winemaker and then resumed the evening’s festivities, united by their mutual love of wine. A whiff of politics couldn’t dim the cheer of celebration and a community united by its love of wine. In Memoriam: Michel Rolland The global wine community lost a giant March 20, with the passing of Michel Rolland. He was 78. Rolland was the original “flying winemaker,” a globe-trotting consultant who helped Bordeaux regain its mojo in the 1970s and then shaped the rise of Napa Valley cult Cabernet as consultant to Simi, Harlan, Newton, Screaming Eagle, Araujo, Dalle Valle and other wineries. He was instrumental in Argentina’s rise to prominence and even had his own winery, Clos de los Siete, in a partnership with other wine families. Rolland’s career arc paralleled that of Robert Parker, the world’s most influential critic. Parker championed many of the wines Rolland consulted on, helping build his reputation and demand for his services. It also made him a target for Parker’s critics. As W. Blake Gray wrote on Wine-Searcher in his excellent tribute to Rolland: Rolland created the type of wines Parker loved: rich body, plenty of fruit, soft tannins. He sometimes faced the accusation of creating a generic international style of red wine, where the great wines he made in Argentina were indistinguishable from the great wines he made in France. Rolland chafed at that critique, as did many of his fans. He was credited with championing green harvesting and leaf pulling, as well as careful selection of grapes in the winery, practices we nearly universally think of today for high-quality winemaking. “Michel was an incredible innovator who changed how wine was made and how grapes were grown,” Napa Valley winemaker Aaron Pott wrote on Facebook. “His work has transformed the wine trade. He created new ways of looking at wine, tasting wine, evaluating ripeness and quality. … This was not just a man with a ‘style’ that he imposed on vineyards but a man that understood how to make great wine from great sites.” Rolland started his consulting company in 1973 in Libourne, in Bordeaux, with his wife, Dany. Both had graduated the year before from Bordeaux’s Institute d’Oenologie. The couple sold their majority share in the business in 2020, according to Wine Spectator. Over his career, Rolland reportedly worked with more than 100 wineries in 20 countries. He even made it to Virginia, where he consulted for Kluge Estate in the mid-2000s. (Kluge Estate is now Trump Winery.) Reader feedback, please! Last week, I did my first WineLine Live! with Dr. Laura Catena of Catena Zapata winery in Argentina. We enjoyed a fascinating discussion about her efforts to preserve the genetic heritage of old vineyards in Mendoza. I conceived of WineLine Live! for paid subscribers, as a thank you for your financial support. And while only a few people joined live, the video now has more views than I have paid subscribers, so I guess that’s pretty good. Even so, I’m considering opening future installments to anyone on Substack to reach a broader audience. So my questions to you: Should these be public? And what format do you prefer? Live gives a chat feature with the potential for viewers to interact with me and the guest, while a video post would just be that. Another alternative is a podcast, which would just be audio, without video of my chins. Please let me know in the comments. Leave a comment In the Glass A few wines I’ve enjoyed recently: Bonny Doon Vineyard Take Me to Your Liter, Le Cigare Volant, Red Wine of the Earth. 2023, Central Coast, CA. Blend of Grenache, Syrah Cinsaut and Petite Sirah. Delightful wine with expressive red fruit flavors, casual drinking. Doon lovers of a certain age will remember Randall Grahm’s Big House Red; this is more in that style than his original Le Cigare Volant, modeled after Chateauneuf du Pape. The liter bottle makes it an even better value. I see this online at about $15. Great value. Albert Bichot Bourgogne Pinot Noir Origines 2023. 13% - Textbook pinot noir and an excellent, affordable entry (regional) Burgundy. Wine Enthusiast Top 100 Wines of 2025. $24 at Total Wine & More. Loma Larga Pinot Noir 2021 “Coastal Cool Climate Wine”, Valle de Casablanca, Chile. An older sample, showing beautifully. Spicy and fruit forward. I’m seeing widely varied pricing online, from $18-$32. At the lower end, it’s a terrific value. 13.5% Dr. Loosen Riesling Dry 2016, Mosel, Germany. Found this “in the stack.” And it stacked up well, shedding some of its youthful acidity for opulent Riesling character, including a hint of the mineral oil older Riesling often features. A great value, as I’m seeing it as low as $14 online. 12% abv. Red Tail Ridge Blau Franc Blend 2024, Sans Oak, Finger Lakes. 13.4% abv. The name is a neat portmanteau of Blaufrankisch and Cabernet Franc, thus Blau Franc. The blend is 50-50, no oak involved. The Blau dominates on the palate, with the spicy caraway seed (think New York deli rye bread). The Franc adds body. The result is juicy, energetic and joyful. Sokol Blosser Estate Rosé of Pinot Noir 2025, Dundee Hills, Willamette Valley, Oregon. This first rosé of 2025 was a welcome respite to our cold, snowy winter here in the Mid-Atlantic. Oh man, I needed this! Bright and energetic, exuberant even, it perks up the mood and goes down fast. 13%. Certified B Corp. Ingredient and nutrition labeling, and in a modest way that doesn’t occupy a lot of label space. (Since it’s not required, presumably there are no minimum font size requirements.) More wineries should follow this example. Dave McIntyre's WineLine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Thanks for reading Dave McIntyre's WineLine! This post is public so feel free to share it. Share 1 Some restraint may be required. 2 Especially the bubblies.

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Mar 23 • 10:54 PM EDT • Politics • dmwineline.substack.com
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Stephanie Laing Signs With Linden Entertainment For Management (EXCLUSIVE)

Director Stephanie Laing has inked with Linden Entertainment for Management. She remains repped by CAA and Myman Greenspan.

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Mar 23 • 12:19 PM EDT • Entertainment • deadline.com
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WSU launches bilingual video series to help beekeepers improve colony health

Researchers with WSU's Honey Bee and Pollinators Program have produced a new video series giving novice keepers a strong introduction to best practices and the science of apiculture, in both Spanish and English.

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Mar 23 • 9:00 AM EDT • Health • news.wsu.edu
Scientists See Converging Evidence of Antarctic Ice Retreat

A sediment core spanning millions of years and new modeling studies point to significant ice retreat under temperatures similar to today.

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Mar 23 • 4:50 AM EDT • Science • insideclimatenews.org
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Here’s how Va. lawmakers suggest the next state budget handle federal health care funding fallout

Spanberger will mull theirs and former Gov. Glenn Youngkin’s budget proposals ahead of a reconvened session on April 23.

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Mar 21 • 1:10 PM EDT • Health • wtop.com
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The insular bubble of caucuses and assemblies

Nearly 30 years ago, then-Federal Reserve Chairman Alan Greenspan coined the term “irrational exuberance” to describe the overheated stock market. That descriptive phrase could also apply to much of the political realm. The hype in politics often grossly exceeds the reality on the ground. In that vein, let’s focus on Colorado’s precinct caucuses held earlier […]

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Mar 21 • 7:00 AM EDT • Politics • coloradopolitics.com
Men are losing a key chromosome with age and it may be deadly

Aging men often lose the Y chromosome in a growing number of their cells—and it may be far more dangerous than once believed. This loss has been linked to heart disease, cancer, Alzheimer’s, and shorter lifespans. Researchers suspect Y-less cells may grow faster and disrupt normal body functions. What seemed like a minor genetic quirk could actually be a major driver of age-related disease.

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Mar 20 • 8:00 AM EDT • Science • sciencedaily.com
Hispanic Women-Owned Business Growth—Revenue Hasn’t Caught Up

Hispanic/Latina women are launching businesses at record rates and leading in employer firm growth. New IWOB data shows why revenue still doesn’t match the momentum—and what changes that.

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Mar 20 • 7:04 AM EDT • Business • forbes.com
The Science Is in: No One Likes Your Cockapoo

The Science Is in: No One Likes Your Cockapoo: Why not get a cocker spaniel or poodle instead?

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Mar 18 • 8:03 PM EDT • Science • nautil.us
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Video: Business Report Hall of Fame honoree Benny Alford

Benny Alford still shows up to work every day. At 80, the founder of Benny’s Car Wash keeps an open door at the company’s corporate headquarters overlooking Airline Highway, greeting employees, family members and the occasional visitor seeking advice. It’s a small but telling detail in a story that spans more than seven decades of […]

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Mar 18 • 8:00 AM EDT • Business • businessreport.com
The race for a safe Democratic House seat offers clues about the party’s future

It’s Primary Day in Illinois, where 15 Democrats, spanning three generations, are vying to succeed longtime Congresswoman Jan Schakowsky in the state's 9th Congressional District. We discuss what the race tells us about the future of the Democratic Party.This episode: senior White House correspondent Tamara Keith, political reporter Elena Moore, and senior political editor and correspondent Domenico Montanaro.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye. Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.

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Mar 17 • 4:48 PM EDT • Politics • npr.org
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Barcelona star to return to starting XI vs Newcastle

A member of the defensive ranks at La Liga giants Barcelona is in line for a return to starting duties in the club’s next outing.That’s according to Diario Sport, who highlight Eric García as the...

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Mar 17 • 4:00 AM EDT • Sports • sports.yahoo.com
Street Fighter 6 Alex and balance update patch notes

The long content drought in Street Fighter 6 that spanned five months is about to be finally over, and there will be quite a bit for players to sink their teeth into.Capcom just released the official patch notes for ...

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Mar 16 • 10:07 PM EDT • Technology • eventhubs.com
Boost your small business with this resource fair

WACO, Texas (FOX 44) – Small businesses are the engine of the local economy – and later this month in Waco, there’s an event designed to help them start, grow and succeed. The CenTex Hispanic Chamber ...

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Mar 16 • 7:07 PM EDT • Business • yahoo.com
US National Academy of Sciences awards four Spaniards for explaining how life escaped an evolutionary dead end

After research spanning more than 30 years, Jordi Bascompte, Bartolo Luque, Fernando Ballesteros, and Enrique Muro managed to explain the abrupt change in living beings that allowed the appearance of plants and animals, including humans

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Mar 16 • 4:54 PM EDT • Science • english.elpais.com
Dana Walden Unveils Her Disney Entertainment Leadership Team Spanning Film, TV, Streaming & Games; Debra OConnell Upped To DET Chairman

Dana Walden Unveils Her Disney Entertainment Leadership Team Spanning Film, TV, Streaming & Games; Debra OConnell Upped To DET Chairman

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Mar 16 • 4:45 PM EDT • Entertainment • deadline.com
Evidence mounts suggesting health costs from WV lawmaker moves on data centers, water

In a span of less than half an hour March 12, 2026, the West Virginia House of Delegates made three moves undermining the state’s already poor drinking water quality. Moves the House of Delegates and Senate have made in the 2026 legislative session's final days are likely to inflict significant health costs, recent studies suggest.

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Mar 14 • 5:30 AM EDT • Health • wvgazettemail.com
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‘How Low Can You Go?’ The Shifting Guidelines for Blood Pressure Control

The number doctors use to demarcate hypertension keeps going down, a trend applauded by many experts, who point to studies linking high blood pressure and dementia.

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Mar 14 • 5:02 AM EDT • Health • nytimes.com
Virginia Dems send sweeping gun ban to Spanberger as West Virginia weighs expanding machine-gun access

Virginia Democrats advance sweeping assault weapons ban while West Virginia Republicans propose allowing machine gun ownership, highlighting sharp divide.

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Mar 13 • 6:54 PM EDT • Politics • foxnews.com
A “ghost” great white shark just reignited a Mediterranean mystery

A rare encounter with a juvenile great white shark caught by fishermen in April 2023 has reignited scientific interest in the mysterious population of these apex predators in the Mediterranean Sea. By reviewing records spanning more than 160 years, researchers found that great whites still appear sporadically in Spanish Mediterranean waters, suggesting the population—though elusive and declining—has not vanished. The discovery of a young shark raises an intriguing possibility: these legendary predators may still be reproducing in the region.

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Mar 11 • 8:00 PM EDT • Science • sciencedaily.com
Two People Die at Paid Plasma Donation Clinics in Canada

Grifols, a Spanish health care company, operates clinics in Canada that collect blood plasma from donors in exchange for an honorarium.

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Mar 11 • 7:05 PM EDT • Health • nytimes.com
WellSpan Health opens new Midstate hospital

(WHTM) — Wellspan Health opened its second Midstate hospital in as many days. The ribbon was cut Wednesday at WellSpan Shrewsbury Hospital. The area needs more health care, since, for many in south…

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Mar 11 • 4:46 PM EDT • Health • abc27.com
Sabalenka credits new dog with providing 'mental health support'

Aryna Sabalenka brought her Cavalier King Charles Spaniel, Ash, whom she credits with providing "mental health support," to a post-match interview following her round-of-16 victory over Naomi Osaka on Wednesday at the BNP Paribas Open.

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Mar 10 • 6:18 PM EDT • Health • espn.com
Apollo to close acquisition of Atletico Madrid stake this week, says Expansion

U.S. fund Apollo's sports investment ​arm Apollo Sports ‌Capital will close the acquisition of 55% ​of Spanish football ​club Atletico Madrid on ⁠March 12, Spanish ​newspaper Expansion said ​on Monday citing sources.

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Mar 9 • 3:33 AM EDT • Business • reuters.com
Why Spanish businesses fear escalating clash with Trump

When it comes to economic warfare, Washington is spoiled for choice.

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Mar 8 • 1:06 AM EST • Business • politico.eu
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Social Determinants of Health and Access to Orthopedic Care Among Seniors in Little Havana

Introduction: Little Havana, Miami, Florida, is a predominantly Hispanic neighborhood with many adults and seniors aged 65 and older at risk for osteoarthritis, osteoporosis, and associated frac...

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Mar 7 • 7:00 PM EST • Health • cureus.com
The Number of Kids You Have May Affect Your Lifespan, Study Finds

Life choices.

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Mar 7 • 7:00 AM EST • Science • sciencealert.com
How to Have a Longer and More Fulfilling Sex Life

With longevity comes the opportunity for an extended sex life, which some seniors find by staying active and open-minded.

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Mar 5 • 10:55 AM EST • Health • nytimes.com
SVG in Indy: Pacers Sports & Entertainment Remotely Produces Broadcasts of G League’s Noblesville Boom

The production method, which spans a distance of 36.2 miles, was designed and implemented by the Pacers’ in-house engineers When the Noblesville Boom became an official franchise in spring 2025,...

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Mar 4 • 7:00 AM EST • Entertainment • sportsvideo.org
Hybrid Solar Panel Turns Raindrops into Electricity

A Spanish research team’s patented thin film generates 110 volts from a single raindrop’s impact.

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Mar 3 • 12:09 PM EST • Science • zmescience.com
Supreme Court preserves only GOP-held congressional district in NYC for 2026 elections

The Supreme Court on Monday sided with Republicans in ruling that the boundaries of the only GOP-held congressional district in New York City do not not need to be redrawn for the 2026 elections, despite a court ruling that the district is unfair to Black and Hispanic residents.

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Mar 2 • 7:17 PM EST • Politics • pbs.org
Josh Kussman Joins Accelint as Senior Vice President of Business Development and Strategy

Accelint has named Josh Kussman as its new Senior Vice President of Business Development and Strategy, bringing on board an entrepreneur, attorney, and longtime homeland security leader with experience spanning government service and the private sector.

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Mar 1 • 12:34 PM EST • Business • hstoday.us
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Today’s NYT Strands Hints, Spangram, Answers: Sunday, March 1 (Dressing Down)

Looking for help with today's NYT Strands puzzle? Here's an extra hint to help you uncover the right words, as well as all of today's answers and Spangram.

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Feb 28 • 10:00 PM EST • Technology • forbes.com
5 Of The Best Wired Headphones For Audiophiles, According To Users

These wired picks span budget to premium options for studio work, gaming, travel, and everyday listening — all with strong user feedback.

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Feb 28 • 3:47 PM EST • Technology • bgr.com
‘No better place:’ America’s earliest politics form the backdrop for Spanberger’s response to Trump

Spanberger said she could “think of no better place to speak to you as we reflect on the current state of our union.”

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Feb 28 • 9:10 AM EST • Politics • dailypress.com
Democrats look to Tejano music star Bobby Pulido in a high-stakes South Texas congressional race

Democrats are banking on Tejano music star Bobby Pulido to help them win back Hispanic voters in a South Texas congressional district that favors Republicans

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Feb 28 • 9:04 AM EST • Politics • washingtonpost.com
Medicare spending set to nearly double in 10 years and Medicaid and ACA spending up a third, CBO says, just as Trump’s tax cut shortens its lifespan

Medicare spending alone will nearly double over the next decade, but the CBO projects its underlying trust fund will run dry by 2040.

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Feb 26 • 5:17 PM EST • Health • fortune.com
Murfreesboro Entertainment Landmark Lanes, Trains and Automobiles to Close After 15 Years

MURFREESBORO, Tenn. (WGNS) — A long-standing pillar of the Rutherford County family entertainment scene is preparing to take its final bow. Lanes, Trains and Automobiles (LTA Depot) has officially announced it will shutter its Murfreesboro operations this spring, marking the end of an era that spanned more than a decade and a half. The decision to close follows a shift in the ownership of the property where the facility is located. According to a statement from the business, the current l ...

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Feb 26 • 7:57 AM EST • Entertainment • wgnsradio.com
Popular brain supplement linked to shorter lifespan in men

A massive study of more than 270,000 people has uncovered a surprising link between a common amino acid and how long men live. Researchers found that higher levels of tyrosine—an amino acid found in protein-rich foods and often marketed as a focus-boosting supplement—were associated with shorter life expectancy in men, potentially trimming nearly a year off lifespan.

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Feb 26 • 7:00 AM EST • Science • sciencedaily.com
Small Business Admin. IG Testifies on Fraud in Small Business Relief Programs

Small Business Administration Inspector General William Kirk and Pandemic Response Accountability Committee Executive Director Kenneth Dieffenbach testify on fraud in small business relief programs before the Senate Small Business Committee.

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Feb 25 • 2:30 PM EST • Business • c-span.org
Javier Palomarez, USHBC President, Warns State of the Union Is Disconnected from Small Business Reality

WASHINGTON, Feb. 25, 2026 (GLOBE NEWSWIRE) -- Last night’s State of the Union address focused heavily on economic momentum, stock market performance, energy policy, immigration enforcement, and tariffs. While President Trump emphasized record market highs and economic resilience, recent polling among Hispanic business owners suggests a widening gap between macroeconomic indicators and kitchen-table reality. According to the United States Hispanic Business Council (USHBC)’s most recent survey of

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Feb 25 • 12:52 PM EST • Business • finance.yahoo.com
Biohacking To Business Travel: Hospitality As Longevity Laboratory

Why hospitality may be the real longevity laboratory—how everyday business travel is redefining healthspan, wellbeing, and the future of the longevity economy.

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Feb 25 • 6:46 AM EST • Business • forbes.com
Abigail Spanberger, in Democratic Response, Asks if Trump Is Working for Americans

“We all know the answer is no,” the Virginia governor argued in her rebuttal to President Trump’s State of the Union address.

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Feb 25 • 12:41 AM EST • Politics • nytimes.com
WATCH: ‘We all know' Trump is not making your life more affordable, Spanberger says

In the official Democratic response to the president’s speech, Spanberger stressed how Trump’s policies on a host of daily issues, from health care to housing, hasn’t made life more affordable.

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Feb 24 • 11:57 PM EST • Politics • pbs.org
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Abigail Spanberger to Give Democratic Response to Trump’s Address

Abigail Spanberger, the newly elected governor of Virginia, was chosen to deliver her party’s response to President Trump’s State of the Union address.

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Feb 24 • 1:11 PM EST • Politics • nytimes.com
Who is Abigail Spanberger? New governor giving the SOTU rebuttal

Virginia Gov. Abigail Spanberger is giving the Democratic response to Trump's State of the Union. Learn more about her background.

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Feb 24 • 10:29 AM EST • Politics • usatoday.com
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Oura launches a proprietary AI model focused on women's health

The model supports questions spanning the full reproductive health spectrum, from early menstrual cycles through menopause.

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Feb 24 • 10:08 AM EST • Technology • techcrunch.com
Oura launches a proprietary AI model focused on women's health

The model supports questions spanning the full reproductive health spectrum, from early menstrual cycles through menopause.

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Feb 24 • 10:08 AM EST • Health • techcrunch.com
What to expect from Virginia Gov. Abigail Spanberger’s State of the Union response

Abigail Spanberger is less known for her oratory than for drilling down into the work of government.

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Feb 24 • 4:00 AM EST • Politics • cnn.com
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Gossip: Reds consider Szoboszlai-Rodrygo swap deal

Liverpool could consider a swap deal with Real Madrid which would bring Brazil winger Rodrygo, 25, to Anfield and allow midfielder Dominik Szoboszlai to join the Spanish giants. Fichajes - in Spanish) Aston Villa, Crystal Palace and Wolves are among the clubs interested in signing Andy Robertson, should the left-back leave Anfield this summer. (Caught Offside)

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Feb 24 • 2:24 AM EST • Sports • sports.yahoo.com
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WATCH LIVE: Gov. Spanberger delivers Democratic response to Trump's State of the Union
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Feb 23 • 8:36 PM EST • Politics • pbs.org
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Special election could delay large Greeley entertainment district development

Voters in Greeley will decide Tuesday whether to repeal already-approved zoning for a massive entertainment district and housing development on the city’s western edge. The proposed development spans...

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Feb 23 • 7:26 PM EST • Entertainment • yahoo.com
Burke County reports first measles case, exposure sites span 3 counties

Burke County has experienced its first measles case, Burke County Public Health confirmed in a Feb. 23 press release.

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Feb 23 • 5:23 PM EST • Health • wlos.com
Alex Padilla Plans Spanish Rebuttal to Trump’s State of the Union

Senator Alex Padilla, a Democrat from California, offered a preview of his remarks, which he expects to focus on the economy, immigration and fair elections.

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Feb 23 • 11:45 AM EST • Politics • nytimes.com
AI bolsters breast radiologists’ cancer detection rate, real world study finds

The study spanned fourt sites and included 9 highly experienced breast radiologists reading over 100,000 DBT exams.

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Feb 23 • 2:51 AM EST • Business • radiologybusiness.com
Spring sports roundup: St. Paul’s rolls past Spanish Fort in baseball opener

Check out the highlights from baseball, softball, soccer and tennis this week.

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Feb 20 • 1:45 PM EST • Sports • al.com
Gov. Abigail Spanberger Will Deliver Democratic Response to Trump’s State of the Union

In selecting the Virginia governor, Democrats turned to a centrist former congresswoman whose winning campaign last year showed how their party’s candidates can succeed in the Trump era.

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Feb 19 • 3:45 PM EST • Politics • nytimes.com
Spanish Business Lobby Urges More Strategic Migration Policy

Spain needs to create a “true migration policy,” even as a government plan to legalize about half a million migrants “makes sense,” one of the country’s most influential business groups said in a report.

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Feb 19 • 10:56 AM EST • Business • bloomberg.com
Democrats recruit content creators in new strategy to win back Latino voters

The strategy, developed by the Congressional Hispanic Caucus’ political arm, is being rolled out in the Houston area as early voting begins for Texas’ statewide primary on March 3.

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Feb 19 • 8:19 AM EST • Politics • spectrumlocalnews.com
Police in Colorado arrest 2 burglary suspects accused of targeting Hispanic businesses
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Feb 18 • 2:32 PM EST • Business • cbsnews.com
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Stone, parchment or laser-etched glass? Scientists find new way to preserve data

Hard disks and magnetic tape have a limited lifespan, but storage developed by Microsoft could last for millennia

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Feb 18 • 11:00 AM EST • Science • theguardian.com
Five Berkeley Lab Scientists Receive DOE Early Career Research Awards

Five scientists from Lawrence Berkeley National Laboratory (Berkeley Lab) have received Early Career Research Program (ECRP) awards from the Department of Energy. The ECRP program, now in its 16th year, was established to bolster the nation’s scientific workforce by supporting exceptional researchers at the outset of their careers, when many scientists do their most formative work. Recipients use the funding to pursue projects that have the potential to solve scientific challenges and advance the country’s STEM capabilities. To be eligible for the program, a researcher must be an untenured, tenure-track assistant or associate professor at a U.S. academic institution, or a full-time employee at a DOE national laboratory or Office of Science user facility, who is within 10 years of having earned their doctorate. Awards to an institution of higher education will be approximately $875,000 over five years, and awards to a DOE national laboratory or Office of Science user facility will be approximately $2,750,000 over five years. This year’s Berkeley Lab awardees and their projects are listed below: Timon Heim: Better detectors for more powerful particle colliders Timon Heim is a staff scientist in the Physics Division. His ECRP project will develop a new type of detector that can track the particles generated by collisions in particle colliders with high spatial and temporal resolution. Current detectors in use at high-energy colliders, like the ATLAS detector at the Large Hadron Collider (LHC) at CERN, can track the trajectory and measure momentum of particles, but they can’t track a particle’s time of arrival with sufficient precision to discern from which of the many particle interactions they originate. Heim’s proposed technology — called a 4D tracking detector, because it captures data about particles’ positions in space and time — aims to solve this challenge, allowing researchers to glean more precise data from collision experiments to uncover new insights into fundamental forces and potentially discover new particles. The enhanced capabilities of 4D detectors will be a necessity for experiments at future colliders, such as the Muon Collider or Future Circular Collider. The project will develop custom microelectronics that process the signal of a pixelated silicon sensor that can register charged particles passing through it in an extreme radiation environment that these colliders produce during operation. The goal is to measure individual particles’ position with 50-micro-meter spatial and 50 pico-second (one trillionth of a second) temporal precision, for an incoming flux of around 1 billion particles per second per square centimeter. Harrison Lisabeth: Studying underground processes to unleash abundant energy Harrison Lisabeth is a research scientist in the Energy Geoscience Division focused on combining real-world experiments and AI to guide development of geothermal energy systems. His project will explore how deep underground rock formations – where geothermal wells are dug – are stressed by chemical reactions of the minerals and mechanical strain from movements in the Earth. A better understanding of subsurface stresses is essential to engineer safe and reliable geothermal wells that access the heat of deep rocks to produce electricity. It is estimated that the U.S. could generate ten times the amount of energy needed to power the grid using geothermal sources. Lisabeth plans to simulate how minerals grow, dissolve, and influence the behavior of surrounding rock in geothermal reservoirs by tracking chemical changes in rock samples under pressure in the lab. The project will also develop machine learning models to predict geologic strain based on field measurements and refine existing models that describe how common rock types deform under stress. Combining these approaches, Lisabeth hopes to develop a framework to predict stress to improve stability and longevity of geothermal wells. Daniel Carney: Pushing the quantum boundaries of particle measurement Daniel Carney is a staff scientist in the Physics Division who uses quantum information science to study particle physics and gravity. At very small scales, “quantum noise” — random fluctuations from the act of measurement — can drown out faint signals from rare processes. Carney’s ECRP project, “Fundamental Physics at the Quantum Limits of Measurement,” aims to build a new mechanical quantum sensor that can measure extremely small particle interactions below the limits of that quantum noise. The approach uses lasers to hold a tiny bead containing radioactive atoms; when one decays, the system measures the bead’s motion and the energy of any particles emitted. The experiment’s initial goal is to search for heavy sterile neutrinos, hypothetical particles predicted by some extensions of the Standard Model. The system could also help measure the mass of the neutrino, study the way particles interact through the electromagnetic and weak forces, and hunt for low-mass dark matter — all unsolved mysteries in particle physics. Callum Wilkinson: Using machine learning to demystify neutrinos Callum Wilkinson is a staff scientist in the Physics Division and part of the international Deep Underground Neutrino Experiment (DUNE) hosted by Fermi National Accelerator Laboratory. DUNE will create an intense beam of neutrinos that interact in detectors in Illinois and, after an 800-mile journey through the earth, in massive detectors in South Dakota. By precisely measuring neutrinos and how they change, researchers will get a better understanding of their fundamental properties and whether they are responsible for why there is so much more matter than antimatter in our universe. Wilkinson’s ECRP project will apply two machine learning techniques to improve the analysis of DUNE’s data and enhance the experiment’s precision. One approach will look for hidden patterns in how neutrinos interact and produce low-energy particles, while the other will help correct for distortions in what the detectors record. The methods will be tested on one of DUNE’s prototype detectors and could be used in other neutrino experiments, improving their measurements and helping scientists build better models. Aditi Krishnapriyan: Machine learning methods that scale as datasets grow Aditi Krishnapriyan is a faculty scientist in Berkeley Lab’s Applied Mathematics and Computational Research Division (AMCR) and assistant professor at UC Berkeley. Her project, awarded through UC Berkeley, will develop machine learning methods that scale with dataset size for modeling complex, multi-scale phenomena. The resulting tools can be applied in a wide range of research, including the study of new electrolytes for batteries or the examination of molecular interactions. ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.

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Feb 18 • 11:00 AM EST • Science • newscenter.lbl.gov
A Chemical Spill Poisoned an Entire Town. Dogs Are Showing Scientists the Fallout.

Scientists are still trying to understand the extent of the damage, and the shorter lifespan of canines can expedite our understanding of these chemicals’ health impacts.

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Feb 18 • 8:30 AM EST • Science • popularmechanics.com
Luke Combs-inspired entertainment spot coming to Orlando. Here’s where

According to a news release, the Orlando location will span approximately 33,000 square feet across three stories, offering guests a dynamic experience influenced by Combs’ music and passions.

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Feb 17 • 1:27 PM EST • Entertainment • clickorlando.com
Oscar-winning actor Robert Duvall dead at 95

Robert Duvall, the Oscar-winning actor best known for “The Godfather,“ Apocalypse Now” and many other tough-guy roles over an acclaimed screen career that spanned six decades, has died. He was 95.

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Feb 16 • 1:08 PM EST • Entertainment • cnn.com
Oscar-winning actor Robert Duvall dead at 95

(CNN) — Robert Duvall, the Oscar-winning actor best known for “The Godfather,“ “Apocalypse Now” and many other tough-guy roles over an acclaimed screen career that spanned six decades, has died.

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Feb 16 • 1:08 PM EST • Entertainment • wkow.com
Should Drug Companies Be Advertising to Consumers?

Aging means “becoming a target” of the industry, one expert said. After decades of debate, politicians of all stripes are proposing bans.

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Feb 16 • 11:06 AM EST • Health • nytimes.com
In First Months as Governor, Abigail Spanberger Kicks Up Heat From the Right

The new governor of Virginia, who ran as a centrist Democrat and a former intelligence officer, says the attacks are a sign of her success.

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Feb 16 • 10:49 AM EST • Politics • nytimes.com
Jose Mourinho contract clause opens door to Real Madrid return

On Tuesday, Real Madrid will be reunited with former manager Jose Mourinho for the second time in a matter of weeks, as they face off against Benfica in the first leg of their Champions League play-of...

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Feb 16 • 3:55 AM EST • Sports • football-espana.net
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Immigration raids driving steep business declines in LA immigrant neighborhoods, report finds

According to the report, the 10 ZIP codes most affected by ICE activity span from the San Fernando Valley to Pico Rivera and Huntington Park.

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Feb 15 • 10:54 AM EST • Business • abc7.com
This family business paid $200,000 in tariffs last year, but won't cut corners

(The Center Square) – La Tienda has been delivering the best of Spanish cuisine to Americans for three decades, but the task has become more expensive after President Donald Trump's

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Feb 15 • 8:41 AM EST • Business • thecentersquare.com
DNA Mutations Discovered in The Children of Chernobyl Workers

A tragedy spanning generations.

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Feb 15 • 6:00 AM EST • Science • sciencealert.com
How long do most planets last?

Planets are born, and they can also "die." So what's the lifespan of a typical planet?

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Feb 15 • 5:00 AM EST • Science • livescience.com
I found the best Presidents Day TV deals on the latest from Samsung, Sony and more

Presidents Day is an excellent time to upgrade your TV, and the deals this year span every popular brand from LG to Samsung.

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Feb 14 • 7:48 AM EST • Technology • cnn.com
The No. 1 Morning Habit a Healthy Aging Expert Swears By

In TODAY.com's Expert Tip of the Day, a longevity researcher reveals the first thing she does every morning to extend her healthspan.

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Feb 13 • 8:00 AM EST • Health • today.com
District basketball tournaments underway. Auburn teams handle Spanaway Lake

The postseason is here and by the looks of it, Auburn is ready.

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Feb 13 • 2:45 AM EST • Sports • sports.yahoo.com
2026 NBA All-Star Weekend Broadcasters & Commentators: What to Know

Get to know the NBA on NBC's broadcast team of commentators and analysts for 2026 NBA All-Star Weekend spanning February 13-15 on NBC and Peacock.

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Feb 12 • 3:03 PM EST • Sports • nbc.com
Bad Bunny's show offers cultural lifeline to a besieged Hispanic community

By Brad Brooks AURORA, Colorado, Feb 12 (Reuters) - Puerto Rican superstar Bad Bunny's Super Bowl halftime show, which celebrated Latino culture in Spanish, offered an uplifting moment of cultural

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Feb 12 • 6:06 AM EST • Entertainment • yahoo.com
Bird poop powered this pre-Hispanic kingdom

The Chincha Kingdom likely used seabird guano to fertilize their corn.

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Feb 11 • 2:00 PM EST • Science • popsci.com
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Spain’s Sánchez Says Musk Is Damaging Mental Health of Teens

Spanish Prime Minister Pedro Sánchez accused Elon Musk of breaking local law and harming the mental health of teenagers in the latest escalation of a public spat between the two.

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Feb 11 • 10:38 AM EST • Health • bloomberg.com