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A common painkiller may be quietly changing cancer risk
Ibuprofen may be doing more than easing aches and pains—it could also help reduce the risk of some cancers. Studies have linked regular use to lower rates of endometrial and bowel cancer, likely because the drug dampens inflammation that fuels tumor growth. Researchers have even found it can interfere with genes cancer cells rely on to survive. Still, experts warn that long-term use carries risks and shouldn’t replace proven prevention strategies.
JCPS proposed budget cuts target mental health practitioners
JCPS has confirmed that mental health practitioner positions are on the chopping block as the district works to reduce its budget deficit.
Germany: A push to reduce the number of federal states
Bavaria's State Premier Markus Söder wants to change Germany's political map, but his proposal to merge federal states is meeting with resistance.
Truist Reduces PT on Flutter Entertainment plc (FLUT) from $280 to $260, Reiterates ‘Buy’ Rating
Flutter Entertainment plc (NYSE:FLUT) is one of the best stocks to buy right now. On January 13, 2026, Truist reduced its price target on Flutter Entertainment plc (NYSE:FLUT) from $280 to $260, while reiterating a ‘Buy’ rating. While previewing 2026 for the U.S. gaming sector, the firm discussed the challenges from the previous year, including […]
AMD Expected To Focus More On RX 9070 XT Than Its Non-XT Variant As It Needs Less Price Adjustments
AMD is reportedly going to focus more on the Radeon RX 9070 XT card instead of the RX 9070 amid DRAM shortages as it reduces the burden of price adjustments.
Microplastics are undermining the ocean’s power to absorb carbon
Tiny plastic particles drifting through the oceans may be quietly weakening one of Earth’s most powerful climate defenses. New research suggests microplastics are disrupting marine life that helps oceans absorb carbon dioxide, while also releasing greenhouse gases as they break down. By interfering with plankton, microbes, and natural carbon cycles, these pollutants reduce the ocean’s ability to regulate global temperatures.
Video Man says his ACA health insurance went from $18 to $650 per month
Colorado resident Andrew Ellis, an Affordable Care Act enrollee, said he had to switch health care plans to a lower rate that reduced his coverage.
Video: Animal Crossing: New Horizons Nintendo Switch 2 Edition vs. Switch comparison
A new video comparison has come in for the new Nintendo Switch 2 Edition of Animal Crossing: New Horizons and its Switch original. Probably the biggest here is load time improvements. On Nintendo Switch 2, loading is reduced by about half. Elsewhere, things are mostly the same. Nintendo hasn’t touched up the graphics in any way, and unfortunately, it’s still...
Push to chip food stamp debit cards to reduce fraud eyed in N.Y. budget
It was embedded in the governor's State of the State agenda.
Push to chip food stamp debit cards to reduce fraud eyed in N.Y. budget
It was embedded in the governor's State of the State agenda.
President Trump Unveils The Great Healthcare Plan to Lower Costs and Deliver Money Directly to the People
President Donald J. Trump’s Great Healthcare Plan is a broad healthcare initiative that will slash prescription drug prices, reduce insurance premiums,
8 ways to boost brain health and reduce your risk of developing dementia
Dementia affects more than 6 million Americans and is blamed for more than 100,000 deaths every year.
Fuelling the Future: How Business, Finance and Policy can Accelerate the Clean Fuels Market
Amid rising global energy demand and evolving market dynamics, clean fuels are a key pillar for a more secure, affordable and sustainable energy system. Examples ranging from biofuels, e-fuels and hydrogen derivatives to lower-carbon fossil fuels offer multiple sources of economic and societal value. This report, produced in collaboration with Bain & Company, highlights the important role of expanding clean fuels in our future energy system. Clean fuels have been shown to reduce import dependence on fossil fuels by 5-15%, while providing two to three times the job intensity of conventional fuels. They can reduce lifecycle greenhouse gas emissions and support productive land use – provided well-designed policies protect land, biodiversity and water resources. The report’s analysis builds on consultations with expert stakeholders to present success stories and key insights to help business leaders and policy-makers overcome barriers to greater investment in the sector. The paper is complemented by a digital playbook of solutions drawing from real-world case studies and success stories from across the clean fuels industry. For more information or to inquire about joining the initiative, please visit the Future of Clean Fuels initiative page.
Perceived Threat From Big Business Growing
A reduced majority of Americans view "big government" as most threatening to the future of the U.S., while a near record-high 37% say "big business" is.
Healey sets out to slash health care red tape
New regulations aim to reduce delays and lower administrative costs.
Synopsys Enters Definitive Agreement with GlobalFoundries For Sale of Processor IP Solutions Business
Synopsys, Inc. (NASDAQ: SNPS ) today announced it has entered into a definitive agreement for the sale of its Processor IP Solutions business to GlobalFoundries (Nasdaq: GFS) (GF). Synopsys' extensive investment in IP quality, comprehensive technical support and robust IP development methodology enables designers to reduce integration risk and accelerate time-to-market. This transaction enhances the focus of Synopsys' IP business on strengthening its leadership position in interface and foundation IP while pursuing the highest-value, AI-driven opportunities from the cloud to the edge for customers spanning HPC, mobile, automotive and consumer. "We are focusing our IP resources and roadmap to further our leadership in essential interface and foundation IP while winning new, high-value opportunities that advance our position as the leading provider of engineering solutions from silicon to systems," said Sassine Ghazi, president and CEO of Synopsys. "GF will be an excellent future
This new Google Photos feature could be great for your phone battery (APK teardown)
Photos could soon limit frequent backups to reduce power consumption.
Artificial intelligence tools expand scientists’ impact but contract science’s focus
Nature - Artificial intelligence boosts individual scientists’ output, citations and career progression, but collectively narrows research diversity and reduces collaboration, concentrating...
Weight-Loss Surgery May Benefit Kidney Health in Obesity
Metabolic and bariatric surgery are associated with a reduced risk for adverse kidney outcomes in patients with obesity, regardless of type 2 diabetes status.
Fact check: Trump’s Detroit economic speech
Inflation hasn’t “stopped.” Consumer prices are up during this presidential term, not “down.” Grocery prices are rising, not starting to fall “rapidly.” US businesses and consumers, not China, pay US tariffs on Chinese imports. It’s impossible to reduce prescription drug prices by “thousands” of percentage points, since this would mean Americans would be getting paid to acquire their medicines.
Nikki Glaser Didn’t Want to Reduce Politics, ICE, Trump to Jokes at Golden Globes: ‘It’s Not Funny’
Nikki Glaser cut jokes about Donald Trump, ICE, and other political topics from her Golden Globes punchlines to avoid trivializing the topics.
Santa Barbara’s Rent Freeze: Politics First, Housing Second
Cities that adopt strict rent freezes see reduced housing supply, less reinvestment in existing units, and declining housing quality over time.
Are Declining Stocking Rates Underexplored By Scientists?
A new study says researchers could be missing important climate and environmental changes associated with reduced livestock grazing.
Doseology Engages McKinney Regulatory Science Advisors to Advance Innovative Oral Pouch Product Development through Science and Regulatory Expertise
Doseology Sciences Inc. (CSE: MOOD) (PINK: DOSEF) (FSE: VU70) ("Doseology" or the "Company") a leader in biotechnology-driven consumer products, today announced a strategic partnership with McKinney Regulatory Science Advisors ("McKinney"), a premier FDA regulatory consulting firm specializing in nicotine and reduced-risk consumer products, to spearhead its regulatory submission strategy and solidify its commitment to scientific leadership in the oral pouch technology space.
Women's health research | FOX 13 Tampa Bay
Research shows that hormone replacement therapy can help reduce brain inflammation and diseases. FOX 13's Danielle Zulkosky reports.
How Can Teams Reduce Patient Burden Without Weakening Their Science?
Have high cholesterol? Follow this science-backed diet, even partially, to lower your level
The Portfolio Diet is a lesser-known but powerful regimen that has been clinically proven to significantly reduce cholesterol
How investment banks, hedge funds, and investment firms are using AI
Finance's biggest firms are considering how AI might impact jobs, how it could cut costs, and reduce "grunt work."
Old Sacramento businesses face challenges amid changing landscape
Business owners in Old Sacramento are facing reduced foot traffic and sales in 2025 due to a series of unexpected changes in the district.
Congress Set to Finalize Science Budgets Rejecting Trump Cuts
The bipartisan deal still reduces funding for many science agencies, including NSF and NASA.
New Year, Same Health Fight
Congress returned from its break facing a familiar question: whether to extend the expanded subsidies for Affordable Care Act health plans that expired at the end of 2025. Meanwhile, HHS Secretary Robert F. Kennedy Jr. broke a promise to Bill Cassidy, the chairman of Senate health committee, by overhauling the federal government’s childhood vaccine schedule to reduce the number of diseases for which vaccines will be recommended. Sarah Karlin-Smith of Pink Sheet, Alice Miranda Ollstein of Politico, and Lauren Weber of The Washington Post join KFF Health News’ Julie Rovner to discuss those stories and more.
Towards a coherent affordability agenda
Democrats are taking advantage of voter dissatisfaction with the Trump administration’s failure to reduce consumer prices, and are proposing a range of policies to increase affordability, whi…
WellSpan Health Announces Comprehensive Migration of Technology Portfolio to AWS
Add to FavoritesWellSpan Health, the leading health care system serving Central Pennsylvania and Northern Maryland, today announced plans for a comprehensive cloud migration of its full technology infrastructure. Together with Amazon Web Services (AWS) as its preferred cloud provider, WellSpan will transition its applications, data and environments from traditional data centers to AWS. This migration will establish the foundation for delivering next-generation, AI-enabled health care solutions that reduce administrative burden and improve outcomes for patients across the region and beyond. Supercharging Innovation, Efficiency and Patient Outcomes WellSpan's migration of systems and clinical applications, which serve 1.2 million patients across nine hospitals and 250+ facilities, is expected to be complete by April 2026, one of the fastest full-scale migrations in the health care industry. This transformation enables WellSpan to unify disparate data systems for care teams and patients alike, achieving operational efficiencies and care improvements that fragmented systems are unable to deliver. “Our comprehensive migration to the cloud accelerates our ability to deploy new clinical capabilities that transform patient care while advancing our overall innovation strategy,” said Roxanna Gapstur, Ph.D., R.N., president and CEO, WellSpan Health. “When a physician can access complete patient imaging in seconds instead of hours, we're not just modernizing technology—we're improving patient outcomes. Our new cloud infrastructure also enables us to quickly implement solutions that will free our clinicians from thousands of hours of administrative work annually so they can focus on what they do best: caring for our communities.” The transition allows WellSpan to move away from a data center-based model and enables the rapid deployment and scale of AI technology. WellSpan’s strategic partner, General Catalyst’s Health Assurance Transformation Company (HATCo), facilitated the collaboration with AWS to support the migration. WellSpan’s transformation journey benefits from HATCo’s specialized technology solutions, as well as General Catalyst and AWS’s significant partnership to improve patient outcomes, which was announced in January 2025. “Our decision to go all-in on AWS will enable insights and innovations impossible in traditional siloed environments,” said Kasey Paulus, executive vice president and chief operating officer, WellSpan Health. “This is the largest health care technology transformation in our region's history, and it positions WellSpan to be a premier partner for technology leaders across the country.” “WellSpan is building a foundation with AWS that will improve care and outcomes for patients across their health system by bringing data together into standardized formats that are optimized for AI applications,” said Dan Sheeran, vice president and general manager, Healthcare and Life Science, AWS. “To do this, it is essential to have the most secure and compliant cloud when handling patient data, along with AWS’s built-in AI governance and responsible AI frameworks that follow the industry’s highest standards to protect patient information. We look forward to continuing to work alongside WellSpan as they unlock the cloud and AI’s full potential to deliver exceptional care to their patients.” Key Benefits of the AWS Collaboration Full Portfolio Migration: WellSpan will transition its applications and data from on-premises data centers to AWS, including full IT environments and specialized applications for functions such as nursing, cardiology, pharmacy and the company’s supply chain systems. This represents approximately 7.5 petabytes of clinical and non-clinical data and more than 300 applications—the most comprehensive health system cloud migration in the Mid-Atlantic region. Approved Architectures: AWS will deliver secure, WellSpan-specific architectures tailored to each build, ensuring compliance and reliability across the health system. Unified, AI-Ready Data: Migrating to AWS enables WellSpan to harmonize data across separate systems, transforming unstructured clinical notes and multi-modal datasets into standardized, AI-ready formats. Accelerated Results and Improved Outcomes: Automated data normalization and processing will enable the deployment of applications that reduce turnaround times for items such as analyzing medical imaging or patient records from days to minutes, helping clinicians get patient results faster and improving overall health outcomes. Reduced Administrative Burden: The transition to AWS will enable swift deployment of AI-powered solutions that reclaim thousands of hours for WellSpan’s clinical and corporate teams, allowing them to focus on patient care rather than paperwork. Elastic Infrastructure: Cloud architecture will enable WellSpan to scale computing resources dynamically, supporting seasonal demand fluctuations without infrastructure investments, as well as the rapid deployment of new services across multiple locations simultaneously. Most Secure, Compliant Cloud: AWS offers the highest network availability of any cloud provider, with more than 166 HIPAA-eligible services and certifications for global compliance standards, including HITRUST CSF. Built-in AI governance and responsible AI frameworks ensure that WellSpan’s data is protected under the industry’s most rigorous standards. Tags:News releaseInnovation and partnerships
CES 2026: The Tone Outdoors T1 solved the biggest problem with leaf blowers
Whisper Aero's new spinoff used aerospace engineering to reduce the annoyance of cleaning your yard.
Small changes, happier year: Science-backed tips for a more positive 2026
Author and positivity expert Deborah Mallow joins us to share simple, science-backed ways to reduce stress, boost happiness, and build better days—without overwhelming New Year’s resolutions.
Back to School, Healthy and Ready: Tips for Navigating Flu Season
As we welcome students and families back for the spring semester, keeping our school community healthy remains our top priority. With flu season continuing into the winter months, it’s especially important that we work together to reduce the spread of illness and ensure students are ready to learn each day. Our campus is taking proactive steps to support the health […]
U.S. health officials reduce the number of vaccines recommended for all children
U.S. health officials have announced major changes to the childhood vaccine schedule, reducing the number of diseases children are routinely protected against from 17 to 11.
South Africa business activity contracts in December at fastest pace in 11 months, PMI shows
South Africa's business activity contracted sharply in December, marking the weakest performance since last January as demand waned and firms reduced purchases and inventories, an S&P Global survey showed on Tuesday.
Trump administration cuts number of vaccines it recommends for every child
Medical experts are slamming the move, saying it could lead to reduced uptake of important vaccinations and increase disease.
Scientists uncover a hidden switch that helps cancer cells thrive
A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer metabolism by controlling the powerful mTOR growth pathway, tying survival and energy use together. This insight explains why MCL1-targeting drugs can be effective—but also why they sometimes damage the heart. Researchers have now identified a way to reduce that risk, potentially unlocking safer cancer therapies.
Health Care Providers Are Dropping a Common Anesthesia Drug That’s Also a Climate Super Pollutant
Limiting use of desflurane helps hospitals reduce their greenhouse gas emissions; the European Union now prohibits its use during most procedures.
Economic, business and technological predictions for 2026: Michael Weidokal
2026 will be another crucial year for our Northeast Ohio region, our country and the world. While there is a great deal of trepidation entering 2026 (with good reason), there are also many reasons to hope that this can be a year in which we reduce the level of political and economic risk in the world. Hopefully, our political and business leaders will work together to tackle the challenges we will inevitably face in 2026, and to take advantage of the opportunities that the new year will bring, writes guest columnist Michael Weidokal.
Swimmer who vanished at Lovers Point was wearing a shark deterrent. What science says about what they do
Studies question whether wearable shark deterrents effectively reduce risk.
Why is Great Canadian Entertainment suddenly offloading most of its B.C. casino assets?
Great Canadian Entertainment, one of Canada’s largest gaming and entertainment companies, will be reduced to a presence of just two properties in B.C. after a recently announced agreement to sell its casino operation in Coquitlam to the Snuneymuxw First Nation.Founded in B.C. more than 40 year
SpaceX moves thousands of Starlink satellites in orbit after near miss with Chinese rival
A SpaceX executive said the move would reduce the "likelihood of collision" with other satellites and space debris.
Downtown Louisville revitalization continues despite business departures
Efforts to revitalize downtown Louisville continue as some major companies, including Humana, LG&E, and Fifth Third Bank, reduce their employee presence in the area.
6 Changes to National Health Policy to Watch in 2026
From the passage of a massive bill that reduced federal funds for Medicaid to a comprehensive overhaul of a federal vaccine advisory panel, Congress and the Trump administration delivered major changes to America’s public health system in 2025. Many of those changes are poised to reshape coverage,
Future Samsung foldables could be lighter while having bigger batteries
Samsung could be planning to reduce the weight of the Galaxy Z Flip 8 and the Galaxy Z Fold 8 to make them lighter than their predecessors.
Digital twins for self-driving chemistry laboratories
Nature Computational Science - Digital twins of self-driving chemistry laboratories may help reduce reliance on costly real-world experimentation and enable the testing of hypothetical automated...
One Health: Can science help prevent pandemics?
Scientists are certain that it’s only a matter of time before the next pandemic strikes. Pathogens jump regularly from animals to humans. But the risks that such zoonoses pose can be reduced.
How Cameroon Fought to Save Its Malaria Program After the U.S. Cut Critical Funding
When the Trump administration slashed foreign aid, it gutted a program that had reduced malaria deaths world wide. In northern Cameroon, health workers tried to protect children in one last rainy season.
Stanford scientists uncover why mRNA COVID vaccines can trigger heart inflammation
Stanford scientists have uncovered how mRNA COVID-19 vaccines can very rarely trigger heart inflammation in young men — and how that risk might be reduced. They found that the vaccines can spark a two-step immune reaction that floods the body with inflammatory signals, drawing aggressive immune cells into the heart and causing temporary injury.
What we have learned about neuroscience in 2025
Researchers studying the human brain shared a lot of fascinating research this year, like how to keep brains young and how to reduce inflammation in joints.
A surprising brain cleanup reduced epileptic seizures and restored memory
A new study suggests temporal lobe epilepsy may be linked to early aging of certain brain cells. When researchers removed these aging cells in mice, seizures dropped, memory improved, and some animals avoided epilepsy altogether. The treatment used drugs already known to science, raising the possibility of quicker translation to people. The results offer new hope for patients who do not respond to existing medications.
This popular painkiller may do more harm than good
Tramadol, a popular opioid often seen as a “safer” painkiller, may not live up to its reputation. A large analysis of clinical trials found that while it does reduce chronic pain, the relief is modest—so small that many patients likely wouldn’t notice much real-world benefit. At the same time, tramadol was linked to a significantly higher risk of serious side effects, especially heart-related problems like chest pain and heart failure, along with common issues such as nausea, dizziness, and sleepiness.
How old is too old for running? Here’s what the science says
While all exercise comes with the risk of injury, there are three things runners can do to reduce this
BP to Sell Majority Stake in Castrol Business for $6 Billion
The UK oil giant will divest a 65% stake, retaining the remaining interest via a joint venture, it said Wednesday. BP is shedding assets to reduce debt and turn around years of lagging performance that put the company in the crosshairs of activist shareholder Elliott Investment Management. It kicked off the sale process for Castrol back in February, when then-Chief Executive Officer Murray Auchincloss unveiled a strategic reset, promising to refocus on oil and gas, slash costs and reduce debt.
Duke Health program brings advanced care right to the sidelines for local high school athletes
A Duke Health Sports Medicine program places doctors and therapists right at the center of local sporting events to deliver immediate holistic injury care in an effort to reduce the need for emergency room visits.
ASTP/ONC seeks relaxation of health IT certification criteria with HTI-5
The proposed rule aims to reduce burdens and costs on health IT developers. It also includes measures to promote FHIR-based interoperability, strengthen information blocking rules and simplify certification of AI models.
CDT Environmental Technology Reports 2025 Unaudited Interim Financial Results and Provides Business Updates
Revenue of $7.3 million and loss per share of $0.11 impacted by reduced project activity due to a slowdown in the PRC economySHENZHEN, China, Dec. 23, 2025 (GLOBE NEWSWIRE) -- CDT Environmental Technology Investment Holdings Limited (Nasdaq: CDTG) (“CDT”, the “Company”, or “we”), a leading provider of waste treatment systems and services throughout China, today reports its unaudited interim financial results for the six months ended June 30, 2025, and provides updates on key business development
Nine mental-health tips for a happier 2026
Regardless of any resolutions you may have for 2026, one thing is for sure: Everyone wants to have a happy new year.While losing weight or saving money may be great goals, the most straightforward path to happiness is caring for your mental and emotional health. A robust body of research shows that simple cognitive and behavioral strategies can reliably boost happiness and reduce stress – and they’re generally free and accessible to all.These strategies don’t have to be super time-consuming, but they do require intention: They only work if you do them.Here, psychologist Valentina Ogaryan, PhD, clinical director of the Simms/Mann UCLA Center for Integrative Oncology, shares her top tips for cultivating more calm, centeredness and happiness in the new year (or anytime):Make time for playPlay isn’t just for kids, and it’s far from frivolous. The National Institute for Play says engaging in silliness, fun and just-for-pleasure activities reduces stress and increases optimism and resilience. A recent review also found that play improves mental health.“Adults can benefit from play as much as children,” Dr. Ogaryan says, “not just as a reward, but something that helps regulate.”So go ahead and dance with your dog, build something with Legos, tell a joke, sing karaoke or do anything else that feels like fun. Don’t worry about being productive, just enjoy yourself. And, if you can, opt for more analog play, Dr. Ogaryan suggests, as a respite from our ever-more-digital world. Move your bodyWhether you dance, ski, do yoga, play pickleball, ride a bike, roller-skate, hike or lift weights, physical movement benefits overall happiness and well-being. A 2018 review study of more than 1.2 million adults in the U.S. found that doing any kind of exercise was “significantly and meaningfully associated” with better self-reported mental health.The sweet spot was 45 minutes of movement three to five times a week, but even short bursts of physical activity can boost brain health, according to the Centers for Disease Control and Prevention.“Movement helps support mood and regulate the nervous system,” Dr. Ogaryan says.Plus: exercise can improve sleep quality, and sleep is essential for mental health.Prioritize sleep“Sleep plays a major role in managing stress,” Dr. Ogaryan says. Research shows that lack of sufficient sleep increases the risk of various diseases, including depression.While stress can interfere with sleep, practicing good sleep hygiene can make logging ZZ’s easier. That means maintaining a consistent bedtime; keeping the bedroom cool, dark and quiet; and avoiding social media, news and stimulating shows before bed.Consume lessWe live in a consumer culture, inundated by endless streams of content and advertising everywhere we go, which makes it easy to get overstimulated.“Something really helpful for stress reduction is to simply consume less,” Dr. Ogaryan says – less news, less social media, less information, less noise, less screen time. “It’s about reducing the input,” she says.Consider setting a maximum number of news articles per day, for example, or a time limit on scrolling. Maybe even go device free for an afternoon or a whole day.Practice present-moment awarenessWith so much coming at us all the time, focusing on the here and now can make life feel more manageable, Dr. Ogaryan says: “When everything feels super overwhelming, when everything feels larger than life, let’s make our world a little bit smaller for that moment in time.”She suggests taking things one day, or even one hour, at a time. Ask yourself: What’s my next right action? Release the need to know how everything turns out and liberate yourself from having to handle everything right now. Let the future take care of itself and just focus on the current moment. Then the next one. Have a daily anchorFrom work to the daily commute to family and life responsibilities, our days can feel jam-packed. Dr. Ogaryan recommends creating a centering daily anchor that can fit into even the busiest day.Maybe it’s a 10-minute walk during your lunch break or mindfully enjoying your coffee in the morning. Let your anchor adapt to your needs each day, she says, but be intentional about using that time to ground yourself and calm your nervous system. You might even say to yourself, “I choose this walk to help me become centered,” or “My day already feels stressful, so I’m going to take the next 10 minutes to enjoy this cup of coffee, feel the warm mug in my hand and just be present.” Having an anchor won’t erase the busy-ness from your day, but it will allow you to approach it more calmly.Be kind to yourselfMost of us have a harsh inner critic in our heads who works overtime. But that critical voice only increases our stress, triggering the same fight-or-flight response as caustic words from another person.To feel happier, we need to replace that inner critic with a kinder, more compassionate voice, Dr. Ogaryan says. Studies show that self-compassion is a source of eudaimonic happiness – the kind of happiness associated with purpose and meaning in life.While our knee-jerk reaction may be to self-criticize – “How could you let it get to this point? You didn’t manage your time well and now the project is going to be late. You’re so inept.” – we fare better mentally by treating ourselves with kindness, like we would a friend. That might sound like, “You’ve got a lot on your plate, but you are capable and you’ll get it done. I believe in you.”We may think that speaking kindly to ourselves means letting ourselves off the hook, so we end up becoming lazy do-nothings. But research shows the opposite: People who are self-compassionate are more likely to try harder in the face of failure and ultimately reach their goals.You can thank your inner critic for its good intentions, but resolve to talk to yourself in a kind, compassionate voice.Connect with othersHumans are social animals built for connection. Stress can be isolating and cause us to withdraw, but connecting with others is a salve for the psyche, Dr. Ogaryan says.“We know that not all relationships are always easy, but if we can think about intentional, nourishing connection – even in really small doses – it could really help center us,” she says.Take a moment to laugh with your colleagues, hug your pet, have a conversation with a friend or smile at the barista making your coffee. A study found that even tiny interactions with casual acquaintances and strangers decreases loneliness and improves happiness and well-being.Seek supportIf you try these practices and happiness remains elusive, or if you can’t access the wherewithal to follow these tips, seek support from your physician or a therapist. Mental health conditions are among the most common health issues in the U.S. and around the world – more prevalent than diabetes or heart disease. One in five people in the U.S. experiences a mental illness each year, with depression and anxiety the most common, according to the National Institute of Mental Health.“We can all think about these tips,” Dr. Ogaryan says. “But it’s important to recognize if you’ve done everything you can and you’re still really struggling, it’s really important to seek help.”
The disunity of science is a feature, not a bug
Mathematical models wield miraculous power, but mistaking them for reality has trapped science in a destructive quest for a “Theory of Everything.” Physicist and philosopher Ragner Fjelland argues that this leads to bloated, Frankenstein theories kept alive by clumsy, ad-hoc amendments, which reduce rather than boost science’s power. Fjelland calls for a radical shift in our attitude: we must reorientate towards creating entirely new theories, celebrating rather than lamenting disunity and diversity in science. Science, from the scientific revolution in the seventeenth century to the present day, has more or less developed in a “reductionist” way. The fundamental assumption is that all sciences may be ordered in a hierarchy that can be represented as an upside-down pyramid. At the top we find the human sciences, and at the bottom physics. Strong (or “ontological”) reductionism maintains that all theories at one level can be completely reduced to the lower level, all the way down to theories of atoms and elementary particles, or whatever is “at the bottom.” In the end, all diversity in the world can be unified in one fundamental theory. Hence it is called a final theory, or a Theory of Everything.One of the central figures in developing the idea of a Theory of Everything is the Dutch theoretical physicist Gerard 't Hooft, who received a Nobel Prize in physics in 1999 for his work. He emphasizes the non-empirical status of the theory:There exists no closely resembling alternative theory. This means that any slight change brought about in the rules would make the theory unlikely or inelegant. The theory will be a "package deal": take it, or leave it. This should hold both for the local laws and for the boundary conditions.This endeavor is not new. On the contrary, it goes all the way back to the birth of Western philosophy 2,500 years ago. The Babylonians made regular astronomical observations during a period of 600 years, from 747 BCE until 150 ACE. They developed mathematical techniques to predict astronomical phenomena, but they made no attempts at explaining them. However, the Greeks developed models, both material and theoretical, to explain the observed phenomena.The best example is Plato’s late dialogue Timaeus. Here he introduces a divine craftsman, the Demiurge, who has constructed the universe according to an original plan. Plato seems to have thought that the original plan is what is actually real, while the material world is merely an imperfect realization of it. He therefore does not, in the Timaeus, reconstruct the material universe, but the original plan, which can then be used to explain the material universe.Plato’s aim in producing a theoretical model is to reconstruct the original plan. That is what he carries out in Timaeus—and some modern physicists have embarked on the same project. For example, Einstein’s basic attitude is reflected in the title of Abraham Pais’ biography: “Subtle is the Lord...,” echoing Einstein’s comment, “Subtle is the Lord, but malicious He is not.” In an interview Einstein compared our situation to a child who enters a huge library. The child knows that someone has written the books, but he does not know the languages in which they are written. He suspects that there is a mysterious order, but he does not know what it is.___“We have all been working in what Husserl called the Galilean style; that is, we have all been making abstract mathematical models of the universe to which at least the physicists give a higher degree of reality than they accord the ordinary world of sensation.”Steven Weinberg, Nobel Prize in Physics (1979)___This Platonist view is contrary to a widespread impression of science, symbolized by the picture of the “father” of modern science, Galileo Galilei, with his telescope. According to this impression, Galileo liberated himself from the dominating metaphysics of his day—basically Aristotelian philosophy—and constructed a telescope that he directed towards the sky, showing that Jupiter has four moons. He also performed experiments with bronze balls rolling down inclined planes and found the law of freely falling bodies.However, in other cases Galileo emphasized the unreliability of our senses. It is easy to see why. He defended Copernicus’ heliocentric hypothesis. According to this hypothesis, we are not at rest at the center of the universe, but moving at a tremendous speed through space. Why don’t we observe this motion? Galileo praises Copernicus because “with reason as his guide he resolutely continued to affirm what sensible experience seemed to contradict.” In other places he directly refers to Plato. SUGGESTED VIEWING The quest for a final theory With Michio Kaku Galileo’s Platonism goes back to his early writings. In The Assayer, published as early as 1623, Galileo compared the universe to a grand book that is written in the language of mathematics, and “its characters are triangles, circles, and other geometric figures without which it is humanly impossible to understand a single word of it.” Therefore, things that cannot be described by mathematics—for example, colors, smells and odors—are not real. They are merely subjective.This division into subjective and objective, advocated by Galileo and his younger contemporary René Descartes, is normally associated with a mechanistic world view, which is regarded as the opposite of Platonism. When we reduce something to, for example, molecules and atoms, we move “downwards.” In contrast, the Platonist moves “upwards,” to abstract entities. However, it only shows that when we address fundamental questions, we should be careful in applying everyday spatial metaphors like “up” and “down.”___Nature is complex, and we cannot in general construct mathematical models that adequately describe the world.___The endeavor of finding a Theory of Everything has been heavily criticized. In 2006, the theoretical physicist Lee Smolin published “The Crisis in Fundamental Physics.” He argued that one of the most fundamental principles of science is that we should only regard theories as scientific if we have the possibility to show that they are false by experiments. Although he did not refer to Karl Popper, other critics have referred to Popper and argued that a theory is not scientific if it cannot be falsified (see for example Ellis & Silk 2014).These were not the first physicists to be anti-reductionists. In 1972, the journal Science published an article by the physicist Philip Anderson with the title “More Is Different.” This is the kind of article a scientist would normally write only after he has won a Nobel Prize. However, Anderson won the Nobel Prize for physics five years later, in 1977. The article is amazing, not primarily because it argues in favor of anti-reductionism in general, but because it argues for anti-reductionism within physics itself. Anderson’s conclusion was:At each stage entirely new laws, concepts, and generalizations are necessary, requiring inspiration and creativity to just as great a degree as in the previous one. Psychology is not applied biology, nor is biology applied chemistry.We may say that Plato started the “unity of science movement,” based on Euclidean geometry as the model of all knowledge. A distinguishing mark of geometry is that all possible constructions can be reduced to a few fundamental principles. We have to acknowledge that this approach has limitations. In general, we can easily model technological systems. In addition, we may construct simplified and idealized models that capture important aspects of systems, from various perspectives and for various purposes. But nature is complex, and we cannot in general construct mathematical models that adequately describe the world. In a complex system, each level has its distinct, emergent, properties that are characteristic of this level. Therefore, a complex system should be investigated at different levels and from different perspectives. Instead of exclusively pursuing a scientific ideal based on the unity of science, we should acknowledge the diversity—or even the disunity—of science.
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The New WHO Pandemic Treaty and Global Health Governance: Incorporating Common but Differentiated Responsibilities into PABS - Georgetown Journal of International Affairs
On May 20, 2025, the World Health Assembly unanimously adopted the World Health Organization (WHO) Pandemic Agreement, an international treaty designed to strengthen pandemic prevention, preparedness, and response. The product of three years of arduous negotiations, the treaty marks a new era of global cooperation in public health. However, core aspects of the agreement remain unresolved—notably the Pathogen Access and Benefit-Sharing (PABS) System, which is intended to ensure equitable access to pandemic-related materials and benefits. To support the successful implementation of the WHO Pandemic Agreement, the principle of “common but differentiated responsibilities” should be formally incorporated into the negotiating agenda of the PABS annex. Introduction For the first time, an international treaty has enshrined the principle of “One Health,” the compelling idea that the health of animals, humans, and the environment all contribute to pandemic risks. SARS (2003), H1N1 (2009–10), Ebola (2014–16), and COVID-19 all emerged through zoonotic spillover from animal hosts—respectively, civets, hogs, and bats. Together, they underscore the need for a coordinated, cross-sectoral approach. The Pandemic Agreement responds to this call, requiring state parties to acknowledge the ecological interplay and commit to a comprehensive “One Health” strategy. Specifically, Article 5 charges governments to address “the drivers of pandemics and the emergence and re-emergence of infectious disease at the human-animal-environment interface,” including wild animal markets, deforestation, and antibiotic overuse. Yet the effectiveness of this “One Health” vision depends equally on the free flow of scientific information and data among countries and institutions. Just as environmental and animal health factors have been neglected in past global frameworks, so too has data sharing been marginalized, despite its centrality to timely detection and response. The Pandemic Agreement takes an important step by requiring governments to enhance data collection and cooperate with the World Health Organization (WHO). However, these provisions will remain aspirational without a robust Pathogen Access and Benefit-Sharing (PABS) annex. The PABS system will determine whether countries and researchers can rapidly exchange pathogen samples and genetic data while ensuring equitable access to resulting research and development, including diagnostics, therapeutics, and vaccines. Without such mechanisms, the treaty’s promise to operationalize “One Health” and strengthen global preparedness will risk becoming largely symbolic, echoing earlier failures to translate shared principles into coordinated action. Equity Concerns When the 2025 Health Assembly adopted the Pandemic Agreement, it left the difficult question of access to pathogens and the sharing of resulting benefits to be addressed in a separate agreement. Negotiations on this separate agreement, PABS, are now underway in Geneva. Yet governments remain divided over fundamental questions of equity between the countries that primarily contribute to the system and those that primarily draw from it—and consequently benefit. For example, wildlife in countries bordering the equator is likely to produce PABS materials, but companies in Europe are likely to use them to develop lucrative products. The most likely contributor countries are likely to be those biodiverse countries around the equator, such as Brazil, the Democratic Republic of the Congo, and Indonesia, where the number of human-mammalian viral host interactions is large. Conversely, countries most likely to benefit from this material are those with the technology, investors, and infrastructure to capitalize on genomic data, such as the United States, EU member states, and Japan. This imbalance reflects a broader pattern seen in prior international frameworks. Now, as in the past, the wealthiest countries in the world (a useful heuristic is membership of the Organisation for Economic Co-operation and Development (OECD)) disproportionately benefit from systems in which pathogens and genomic sequencing data are contributed to a common source. Under the International Agreement on Plant Genetic Resources for Food and Agriculture (the “Plant Treaty” or “Seed Treaty”) and the Pandemic Influenza Preparedness (PIP) Framework, companies from Europe and North America disproportionately withdraw biological samples and data for development into lucrative medical products. Their governments and companies have both statutory and contractual claims to the products that those companies correspondingly produce. PABS appears poised to follow the same pattern. The text calls for strong language on access to pathogens and associated data, but the corresponding benefits that should flow to poorer countries are couched in equivocal or non-binding language. Common but Differentiated Responsibilities To address these inequities, the principle of “common but differentiated responsibilities” should be formally incorporated into the negotiating agenda of the PABS annex. Common but differentiated responsibilities are often a feature of climate change negotiations. The basic principle is that, even though all countries should reduce carbon emissions, governments that became rich and powerful through massive carbon emissions (e.g., France, the United Kingdom, the United States) should have a greater obligation to address the resulting crises. Applied to PABS, it would require that governments hosting and supporting companies developing lucrative products carry greater obligations toward the cost of running the PABS system; share benefits or final medical products; and transfer technology to help countries worldwide develop their own capacities to innovate and manufacture vaccines during an emergency. For example, an annex could mandate that any company based in an OECD country that withdraws PABS material would be obligated to donate the resulting diagnostics, therapeutics, or vaccines to the WHO during a public health emergency or pandemic. Questions remain about how robust those donations would be, but the principle is that they should deliver highly significant lifesaving benefits to be equitably shared. Theoretically, this approach mirrors the PIP Framework, in which companies withdrawing influenza samples are required to pay half of the operating costs. In practice, however, the framework has fallen short. The PIP Framework Secretariat has struggled to secure payments from companies, with companies often disagreeing over how much is owed. Additionally, without another pandemic influenza to test the strength of the agreement during a public health emergency, corporate compliance with sharing mechanisms remains unknown. Even if these limitations did not characterize the PIP Framework, partially paying for operating expenses does not address the inequity in access to genetic data and pathogen samples that left less developed countries last in line for COVID-19 vaccines (and, before them, H1N1). Common but differentiated responsibilities would go further, addressing governments’ legitimate grievances regarding information sharing. It would make withdrawals of PABS material and resulting products more transparent, building trust across the board. Enforcement and Enduring Success A key implication of this approach is that the governing mechanism of the PABS must have real enforcement authority. The WHO Pandemic Agreement delegates its core governance responsibilities to a Conference of the Parties (COP)—a governing body composed of one representative from each participating government, similar to those established under the UN Framework Convention on Climate Change and the WHO Framework Convention on Tobacco Control. The proposed WHO Pandemic Agreement COP is charged with oversight functions but ultimately possesses no real authority to compel a government to take any action it does not wish to take. The text does not give the COP the ability to, for example, sanction a party that does not comply with either textual obligations or PABS provisions. In other words, there are no effective mechanisms in place to ensure compliance. Perhaps just as significant, establishing a meaningful enforcement mechanism within the PABS system would strengthen the WHO’s credibility and its ability to ensure compliance across global health governance. By setting a precedent for accountability, such a mechanism could enhance the organization’s authority not only within the Pandemic Agreement but also in enforcing the revised International Health Regulations and other frameworks for public health emergencies. Conclusion The PABS annex can—and should—be different. It should establish clear responsibilities for funding as well as for sharing the diagnostics, therapeutics, and vaccines that result from contributions to the system. The system, in turn, must include a dedicated body empowered to hold governments and the corporations they sponsor accountable for their responsibilities before, during, and after pandemics. Doing so would restore trust in the broader agreement, which was eroded as commitments were repeatedly diluted while parties scrambled to meet their own self-imposed deadlines during the Pandemic Agreement negotiations. A robust PABS Annex would cement a grand social bargain. Wealthier countries and their corporations would gain unimpeded access to scientific information essential for developing and manufacturing lifesaving medical products. As such, they would stand to gain considerable economic benefit. Yet that privilege must be matched with responsibility. The grand bargain must include not only the right to innovate, but also the duty to ensure that innovation serves all. As medical products are developed and produced through collective contributions, every person must have equal access. All human beings deserve an equitable chance to survive—to save their own life, the lives of their families, and the well-being of their communities. … Sam Halabi, JD, MPhil, is the Bette Jacobs Endowed Professor at Georgetown University’s School of Health and the Director of the Center for Transformational Health Law at Georgetown Law. He serves as the co-lead for the WHO’s Working Group on Regulatory Consideration on AI and Health’s training workstream. He earned his JD from Harvard, his MPhil from Oxford, and undergraduate degrees from Kansas State University. Lawrence Gostin, LLD (Hon.), JD, BA, is University Distinguished Professor and Founding Director and Timothy and Linda O’Neill Professor of the O’Neill Institute for National and Global Health Law. He is the author of Global Health Security: A Blueprint for the Future (Harvard University Press, 2021); Global Health Law (Harvard University Press, 2014); Public Health Law: Power, Duty, Restraint (University of California Press, 3rd ed., 2016); Public Health Law and Ethics: A Reader (University of California Press, 3rd ed., 2018); Law and the Health System (Foundation Press, 2014); Principles of Mental Health Law & Practice (Oxford University Press, 2010). He also directs the WHO Collaborating Center at Georgetown University. Image Credit: United States Mission Geneva, CC BY 2.0, via Wikimedia Commons
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