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West Louisville program addresses mental health stigma among Black men

A West Louisville program is creating space for Black men to talk openly about mental health.

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Jul 12 • 11:54 AM EDT • Health • spectrumnews1.com
How ready is Los Angeles for the 2028 Olympics?

Los Angeles area State Senator Ben Allen discussed Los Angeles' preparations for the 2028 Olympics, addressing lessons from the World Cup, infrastructure needs, and collaboration with federal and local partners.

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Jul 12 • 11:25 AM EDT • Politics • kcra.com
Microsoft defends Asha Sharma, says she is an American CEO and Xbox layoff had nothing to do with H-1B

As Asha Sharm, the CEO of Xbox, came under vicious trolling after the gaming division of Microsoft announced the elimination of 3,200 positions, Microsoft came to her rescue and clarified that it had nothing to do with replacing Americans with foreign workers. Frank X Shaw, the lead for the communications for Microsoft, also addressed the 'Indian-origin' angle of the immigration debate and called Asha an American born, educated CEO from Wisconsin.

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Jul 11 • 1:47 PM EDT • Technology • timesofindia.indiatimes.com
Black Men’s Mental Health Conference hopes to address barriers for better outcomes

The conference runs until 2 p.m. Saturday, July 11 at Western Middle School for the Arts (2201 W. Main St.).

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Jul 11 • 12:13 PM EDT • Health • wave3.com
Senate bill tries to 'fix' college sports

Sens. Maria Cantwell, D-Wash., and Ted Cruz, R-Texas, are spearheading new legislation addressing many of the concerns surrounding college athletics

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Jul 10 • 5:00 PM EDT • Sports • spectrumlocalnews.com
Mayor Mamdani addresses whether Taylor Swift is covering costs for police presence at MSG wedding

New York City mayor Zohran Mamdani addresses whether newlywed Taylor Swift is covering costs for the extra police presence at her and Travis Kelce’s Madison Square Garden wedding.

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Jul 10 • 4:52 PM EDT • Entertainment • ew.com
New ‘RHOC’ Housewife and former Playboy Playmate addresses if she slept with Hugh Hefner

New ‘Real Housewives of Orange County’ housewife and former Playboy Playmate Carmella Garcia answers intimate questions about Hugh Hefner on the reality show’s season 20 premiere.

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Jul 10 • 11:33 AM EDT • Entertainment • ew.com
Apollo inks €3B equity deal for stake in Bayer's contraceptives business

Amid restructuring efforts, Bayer has addressed its need for a capital infusion in pharma under a deal

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Jul 10 • 11:31 AM EDT • Business • fiercepharma.com
Ferris State College of Health Professions leaders say building renovation, expansion will help meet demand, grow healthcare workforce

Ferris State University leaders are taking the first steps to plan for extensive renovations to the Victor F. Spathelf Center for Allied Health, modernizing and expanding programs that train the next generations of health professionals and address statewide shortages.

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Jul 10 • 8:00 AM EDT • Health • ferris.edu
UWA expands healthcare education under College of Nursing and Health Professions

The University of West Alabama is expanding its College of Nursing to become the College of Nursing and Health Professions, a strategic initiative designed to strengthen healthcare education, foster interdisciplinary collaboration, and address the growing demand for healthcare professionals across Alabama and the Black Belt region.

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Jul 9 • 5:14 PM EDT • Health • uwa.edu
Phillies Eyeing Padres Closer Mason Miller to Strengthen Struggling Bullpen

Despite the disappointing start to the 2026 MLB season, which led to the firing of manager Rob Thomson, the Philadelphia Phillies are right back in postseason talks. While interim manager Don Mattingly and the current roster have put the team back into contention, there are several areas of concern. The bullpen has been a clear weakness, which the Phillies are expected to address before the Aug. 3 trade deadline.

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Jul 9 • 4:00 PM EDT • Sports • sports.yahoo.com
Fort Bend County Fair Announces 2026 Entertainment Lineup Featuring Sawyer Brown, Pat Green

ROSENBERG, Texas (Covering Katy News) — The Fort Bend County Fair has announced its entertainment lineup for its 90th annual celebration, featuring a mix of Texas country stars, Tejano favorites and nationally recognized performers during Championship BBQ Weekend and the fair's 10-day run. The 2026 Fort Bend County Fair begins with Championship BBQ Weekend on Sept. 18-19, followed by the fair Sept. 25 through Oct. 4. The entertainment schedule opens Friday, Sept. 18, with Tejano group Los Morales, followed by Texas country artist Cole Phillips on Saturday, Sept. 19. Phillips has gained attention for his traditional country sound influenced by classic honky-tonk music. The fair officially opens Friday, Sept. 25, with Tyce Delk, a New Mexico native whose touring schedule has expanded across the country. Country music veterans Sawyer Brown will headline Saturday, Sept. 26. The band, whose career spans more than four decades, remains known for hits including "Some Girls Do," "The Race Is On" and "Thank God for You." Go Tejano Day on Sunday, Sept. 27, will feature Prófugos de Nuevo León, along with performances by Los Rinches and Grupo Zenio. The second week of the fair begins Wednesday, Sept. 30, with Bellville singer-songwriter David Lewis, a recent Texas Country Music Association Male Artist of the Year nominee. Oklahoma Red Dirt artist Josh Meloy will perform Thursday, Oct. 1. Texas country star Pat Green returns to the Fort Bend County Fair stage Friday, Oct. 2. Green, whose career includes three Grammy Award nominations, has sold more than 2 million albums and amassed more than 200 million career streams. He is best known for songs including "Wave on Wave" and "Carry On." Country newcomer Vincent Mason will perform Saturday, Oct. 3. Mason has accumulated more than 500 million career streams and was recently nominated for Academy of Country Music New Male Artist of the Year. The fair concludes Sunday, Oct. 4, with Texas music legend Gary P. Nunn, whose "London Homesick Blues" remains one of the state's most recognizable songs. Weekend visitors also can enjoy performances on Music Row by J Paul Jr. & the Zydeco Nubreeds, Southern County Line, Los Rangerz and Horizon. The Fort Bend County Fair Association, a nonprofit organization, supports youth, agriculture and education. According to the association, it has awarded more than $2 million in scholarships during the past decade and generated $1.4 million through its 2025 youth auctions. Tickets go on sale at 10 a.m. Friday, July 10. Guests are encouraged to purchase tickets in advance and select the specific day they plan to attend, as tickets are valid only for the date purchased. Admission includes entry to the fairgrounds, access to the carnival, shopping, exhibits, food vendors and, when scheduled, admission to the rodeo and that day's concert. Season passes and single-day tickets will be available. For tickets and additional information, visit fortbendcountyfair.com or call the Fair Office at 281-342-6171. The address of the Fairgrounds is 4310 Texas 36 S in Rosenberg. 2026 Fort Bend County Fair Entertainment Schedule Championship BBQ Weekend Friday, Sept. 18: Los Morales Saturday, Sept. 19: Cole Phillips Fair Entertainment Friday, Sept. 25: Tyce Delk Saturday, Sept. 26: Sawyer Brown Sunday, Sept. 27 (Go Tejano Day): Prófugos de Nuevo León, Los Rinches and Grupo Zenio Wednesday, Sept. 30: David Lewis Thursday, Oct. 1: Josh Meloy Friday, Oct. 2: Pat Green Saturday, Oct. 3: Vincent Mason Sunday, Oct. 4: Gary P. Nunn × Expand FBCF Fort Bend County Fair 2026 Artist Lineup

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Jul 9 • 12:00 PM EDT • Entertainment • coveringkaty.com
Hawaii is America's Worst State for Business in 2026, even its legendary quality of life takes a dip

Hawaii, America's Worst State for Business in 2026, is trying to address one of the few disadvantages it can control: quality if life. It isn’t easy.

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Jul 9 • 8:42 AM EDT • Business • cnbc.com
Russian Rail Giant Wants Business to Bear More War Economy Pain

Russia’s largest employer is trying to address mounting financial pressures with new measures that some businesses worry will come at their expense, underscoring the growing strains on the economy as President Vladimir Putin’s war in Ukraine drags on.

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Jul 9 • 6:30 AM EDT • Business • bloomberg.com
AHA itemizes ‘immediately addressable’ aspects of affordability

The American Hospital Association is banging the drum on healthcare affordability.

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Jul 8 • 9:21 PM EDT • Health • healthexec.com
Small Business Spotlight: Business blooms beyond bouquets

BUSINESS: The Busy Bloom OWNERS: Amanda and Walter Adkins ADDRESS: 708 S. 17th St., Wilmington EMAIL: thebusybloomco@gmail.com WEBSITE: thebusybloomco.com PHONE NUMBER: (910) 742-0790 YEAR FOUNDED: 2024 NO. OF EMPLOYEES: 4 WHAT IS THE BUSY BLOOM? AMANDA ADKINS: “The Busy Bloom is a flower shop with a spin – a creative experience shop located in Wilmington’s Cargo District. Founded in 2024 by husband-and-wife team Amanda and Walter Adkins, we offer fresh flowers, botanical teas, a build-your-own bouquet bar, candle-making experiences, gifts, workshops, wedding florals and event services. Our mission is simple: to make flowers accessible, approachable and enjoyable for everyone – not just for special occasions.” WHY DID YOU START THE BUSINESS? AMANDA ADKINS: “The Busy Bloom was born from a lifelong connection to flowers and a desire to create meaningful experiences for people. After doing my own wedding florals and after years of working in healthcare management, I found myself returning to gardening and floral design as a creative outlet and source of healing. The loss of my mother-in-law, who always shared flowers from her garden, inspired me to pursue floristry full-time. My husband encouraged me and built a small flower cart for us to grow, and fast forward to now, two years later, it has grown into a community-centered business focused on bringing joy, connection and creativity through flowers.” WHAT KIND OF GROWTH ARE YOU HOPING FOR? AMANDA ADKINS: “We’re focused on sustainable growth that allows us to continue serving our community while expanding creative experiences. We hope to grow our wedding and event services, expand our educational workshops and creative programming and become a destination where people can gather, create and connect. We’re also passionate about creating opportunities that showcase floral design as an art form, such as our Fleur Couture fashion show and other community collaborations.” WHAT PAST EXPERIENCE HAVE YOU HAD WITH STARTING/WORKING IN BUSINESS? AMANDA ADKINS: “Before opening The Busy Bloom, I worked as a clinical manager in healthcare and spent years building leadership, operations and customer service skills. I’ve also worked in education and nonprofit programming, teaching people about nature and local ecosystems. Along the way, I designed flowers for weddings and events on the side, gradually turning a passion into a business. Walter has years of welding and construction experience, combined with entrepreneurship and a drive to own his own company. …The Busy Bloom has been a journey of combining creativity with entrepreneurship alongside my husband ... learning every step of the way.”

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Jul 8 • 9:28 AM EDT • Business • wilmingtonbiz.com
Global Conflicts Overshadow NATO Leaders' Meeting in Türkiye

Türkiye emphasized the importance of maintaining a comprehensive 360-degree security approach by NATO member states that address threats.

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Jul 8 • 5:45 AM EDT • Politics • politicstoday.org
Officials search for source of Upper East Side Legionnaires' outbreak linked to 28 cases

Officials say they plan to release the addresses of any building whose cooling towers test positive during the initial screening process.

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Jul 8 • 4:58 AM EDT • Health • abc7ny.com
Big 12 commissioner declines to address Sorsby gambling saga

The first thing Brett Yormark was asked about after his opening remarks at Big 12 football media days was the Brendan Sorsby gambling saga.

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Jul 7 • 4:21 PM EDT • Sports • spectrumlocalnews.com
Mac Jones addresses potential 49ers QB battle in 2026

Mac Jones is content with his role on the San Francisco 49ers despite how well he played in 2025.

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Jul 7 • 3:25 PM EDT • Sports • sports.yahoo.com
😐 Neutral (10%)
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Musk-linked mailers draw complaints for targeting wrong addresses, dead voters

Election officials in North Carolina and Georgia are warning about suspicious voter-registration mailers linked to Elon Musk.

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Jul 7 • 2:18 PM EDT • Politics • washingtonpost.com
ACC takes on DOAC use with new scientific statement

Direct oral anticoagulants continue to be underutilized and inappropriately dosed. The American College of Cardiology hopes a new scientific statement can help address those issues and provide clinicians with an updated look at this important topic.

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Jul 7 • 1:09 PM EDT • Business • cardiovascularbusiness.com
‘Avatar Aang: The Last Airbender’ ‘official’ first look (exclusive)

‘Avatar Aang: The Last Airbender’ creators exclusively delve inside Team Avatar’s animated movie, address that leak, and discuss the Aang Gang as adults.

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Jul 7 • 11:00 AM EDT • Entertainment • ew.com
Jesse Thaler named director of the Laboratory for Nuclear Science

Jesse Thaler has been named director of the MIT Laboratory for Nuclear Science. Thaler is a theoretical particle physicist who combines techniques from quantum field theory and machine learning to address outstanding questions in fundamental physics.

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Jul 7 • 10:45 AM EDT • Science • news.mit.edu
A model global health academic partnership flourishes in Botswana

The Botswana-UPenn Partnership has surpassed its goal of addressing HIV/AIDS and has broadened its scope to enhance national access to care and training.

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Jul 7 • 8:00 AM EDT • Health • pennmedicine.org
Türkiye Urges NATO to Turn Defense Spending into Military Capabilities

Looking at the NATO summit in Ankara, Guler described the gathering as a critical opportunity to reinforce unity and address key issues.

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Jul 7 • 3:36 AM EDT • Politics • politicstoday.org
Men’s health fair planned Friday

PARKERSBURG — Youth participants in the Student Summit are addressing men’s mental health and will host a fair Friday at Boys & Girls Club of Parkersburg. The summit is a leadership and advocacy program hosted by the Boys & Girls Club of America. Four club teens chose men’s health as the topic for their advocacy […]

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Jul 6 • 8:00 PM EDT • Health • newsandsentinel.com
Canadiens Have 3 Notable Roster Needs To Address
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Jul 6 • 6:30 PM EDT • Sports • sports.yahoo.com
Brad Stevens Press Conference: Celtics President Addresses Jaylen Brown Trade

Follow along right here for Brad Stevens' most notable comments from Monday's press conference.

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Jul 6 • 3:30 PM EDT • Sports • sports.yahoo.com
Deep dive
😐 Neutral (19%)
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100%
'Big Brother' host Julie Chen Moonves addresses new post-abduction security measures

One year after being abducted on-air, 'Big Brother' host Julie Chen Moonves is confident enhanced security measures will keep her safe.

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Jul 6 • 8:27 AM EDT • Entertainment • ew.com
Could Santos help solve Man Utd's midfield malaise?

Chelsea's Andrey Santos is the latest player Manchester United have taken an interest in as they look to address their problem midfield position. With Casemiro leaving after his contract expired on 30 June and Manuel Ugarte expected to be sold, United went into the summer with England's Kobbie Mainoo as their only recognised central midfielder and with the stated aim of addressing the situation as a matter of priority. In the transfer market, United have encountered more issues.

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Jul 6 • 3:47 AM EDT • Sports • sports.yahoo.com
Keri Hilson breaks down her viral “music can harm” tweet and weighs in on the state of the industry

Keri Hilson music can harm tweet: The “Pretty Girl Rock” singer addressed her cryptic post on X at the 2026

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Jul 5 • 7:56 PM EDT • Entertainment • yahoo.com
WATCH: Trump delivers keynote address at ‘Salute to America 250’ event on the National Mall

Speaking in Washington after storms prompted a roughly two-hour evacuation of the National Mall, Trump honored veterans, including several from World War II and one of the first Black officers to lead a Special Forces team in combat in Vietnam.

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Jul 5 • 11:48 AM EDT • Politics • pbs.org
Ariel Roblin: DACA delays are disrupting lives and business

Our government needs to modernize the system to process DACA reauthorizations and hire the staff to address processing delays. No one should lose their livelihood, critical employees, or their homes, over slow paperwork.

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Jul 5 • 8:00 AM EDT • Business • kcra.com
The strangest show on earth: lightning, imperial hubris and a boring tour of Trump’s rhetorical back alleys

Would we get a 21st-century Gettysburg address? Or YMCA, gripes about his legal woes and boasting about Iran?

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Jul 5 • 4:39 AM EDT • Politics • theguardian.com
In Fourth of July Speech, Trump Celebrates America and Derides Foes

A centerpiece address for the nation’s 250th anniversary celebration devoted time to American history, but had all the hallmarks of a Trump rally.

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Jul 5 • 12:51 AM EDT • Politics • nytimes.com
Trump uses America’s 250 speech to honor military heroes and also push political agendas

President Trump concluded the semiquincentennial celebration by reflecting on the nation's history, honoring veterans and pushing his political agenda during his address at the Salute to America event. NBC News’ Ryan Nobles reports on key points from the president's speech.

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Jul 5 • 12:21 AM EDT • Politics • nbcnews.com
High-Signal Publisher
🙂 Positive (35%)
Derek Shelton Addresses Minnesota Twins' Ugly Night Against the Yankees

Minnesota went 1-for-12 with runners in scoring position on Friday, but the bigger picture still looks promising.

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Jul 4 • 3:49 PM EDT • Sports • sports.yahoo.com
Gov. Wes Moore on ‘responsibility’ to show ‘patriotism is not political’

Gov. Wes Moore (D-Md.) joins Meet the Press NOW to preview his upcoming address on America’s 250th birthday as President Trump prepares to deliver his own remarks.

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Jul 3 • 5:11 PM EDT • Politics • nbcnews.com
High-Signal Publisher
Jordan Spieth Warns Sports Betting Could Harm Golf Fan Behavior at Tournaments

Jordan Spieth believes the growth of sports betting is changing fan behavior at golf tournaments and says the issue may soon need to be addressed.

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Jul 3 • 4:44 PM EDT • Sports • sports.yahoo.com
Long Reads for the Long Weekend

(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) Happy Fourth of July weekend! As has been a tradition of mine going back to the beginning of the EntStrategyGuy website, I’m sharing my favorite long reads of the last year, like I did in 2019, 2020, 2021, 2024, and 2025. Let’s dive right in! Subscribe “Different Prices for the Same Ride: How Uber and Lyft Use AI to Get More Money Out of You“ by Derek Kravitz in Consumer Reports I don’t think surveillance pricing, like the kind described in this brilliant Consumer Reports article, is long for the world—it’s toxically unpopular—but we’ll see if either party takes on this issue. If I ran a political party focused on affordability, I would focus on a few pro-consumer and pro-market policies: Banning non-compete agreements. Ending surveillance pricing Eliminating junk fees (read more here...) Ensuring “right to repair” for consumer (and military!) products Capping excessive app store fees Stopping digital/algorithmic price-fixing tools. Preventing automatic subscription price increases. And more. If you want to fight inflation, there are a lot of great ways to do it quickly. Speaking of higher prices... “Secret Documents Show Pepsi and Walmart Colluded to Raise Food Prices Across the Economy“ by Matt Stoller in BIG Again, I think a political party should focus on lowering prices for consumers. And deals like this—Walmart making a deal/forcing Pepsi to offer the lowest prices at its stores and nowhere else—hypothetically lower prices at Walmart...but raise them everywhere else. “15 DUIs, still driving: California’s failure to take repeat drunk drivers off the road“ by Robert Lewis and Lauren Hepler in CalMatters CalMatters does terrific reporting in California, something the Golden State desperately needs more of, and this article is a great example of that. “PugLips: The next insanely popular thing you’ve never heard of…” by Simon Carless in Game Discover Co I thought that this parody article (and yes, it’s a parody, but I was definitely unsure at first) was hilarious and totally nailed how much tech/business journalism feels these days. Actually, three of my favorite articles this year were on hype in the video game industry, including Georg Zoller’s “The Video Game Industries Very Dark Night”—which I linked to recently and wrote a follow-up here—and Owen Mahoney’s “Derek Zoolander, Videogame Exec”. In particular, I like Mahoney’s focus on user experience as a guide to what trends will actually grab hold of customers. “The Matrix Lies“ by Evan Shapiro in Media War & Peace Evan Shapiro’s first person account of his experience with AI was hilarious. I think LLMs capabilities have significantly grown from last summer, and yet...my editor/researcher just had an abysmal experience using an LLM to do a quite basic task (which our LLM normally does each week) and the LLM made a mistake on every single data entry...along with seven different mistakes affecting twelve of the twenty or so entries, including mistakes that are explicitly spelled out in the prompt. That’s a brutal failure rate. Again, if you use AI/LLM for data collection, you need to take a lot of extra steps to verify and check the data. “Ghosts in the Balcony: A Cross-Country Trip to 58 Theaters Fighting to Survive“ by Matthew Frank in The Ankler I thought Matthew Frank’s pitch to head across America to visit theaters sounded insane aggressive at the time—at least it felt that way to someone a decade older than him; man, to be in your twenties again, am I right?—but I knew the result would be great. And it was, a terrific feature by a great young writer. Also, I loved Matthew’s recent article on who’s getting the precious few entry level jobs in Hollywood. (Hint: nepotism.) “Disney erased FiveThirtyEight“ and “Did Las Vegas get too greedy?” by Nate Silver in Silver Bulletin I love media history and analysis, and there’s no one better to get the history of FiveThirtyEight than from Nate Silver, who wrote about his personal experience in one of my favorite pieces from this year. I also loved Nate’s breakdown of what’s causing Vegas’ woes, but I’ll offer one criticism, summarized as “Might I suggest antitrust?” Many centrists/center-right/libertarian thinkers (Nate is self-described as the latter) often don’t consider consolidation or antitrust as factors in policy issues like housing, America’s military readiness, or, in this case, Las Vegas. Even if libertarians want to debunk antitrust/consolidation concerns, I’d love to read that debunking. In this case, Vegas is incredibly consolidated (though it also has been for a long time) and I’d have loved to read Nate at least contending with this factor, since he addresses almost every other potential factor for Vegas’ decline. “Why Microsoft’s Carbon Removal Pullback Is Such a Big Deal“ by Robinson Meyer in Heatmap News I’m a big supporter of carbon removal efforts, but this nascent industry faces a lot of headwinds, including this big move most recently. I think it’s clear that solar panels and batteries should be able to get the world to its carbon footprint goals, but effective carbon renewal remains necessary to prevent the worst impacts of global warming. “AI is killing the cheap smartphone“ by David Oks LLMs and AI will impact the world in ways we’re not ready for, and already, third world countries are seeing the prices of cheap cellphones skyrocket due to the cost of chips skyrocketing. This article by David Oks is a terrific breakdown. “100 Days of Madness: Netflix, Paramount, Warner and the Future of Hollywood“ by Wade Major at Hollywood Heretic Wade Major dove deep into Hollywood/streaming’s financials in this must read piece. Not that I agree with everything in this article (read my take on Warner Bros./Paramount here) but the analysis is top notch. I think many people discount how quality thinking, regardless of the argument/conclusion, will make you a better thinker. “Erased by the UFC: Frank Shamrock, The MMA GOAT of the 20th Century“ by Nate Wilcox in The MMA Draw Newsletter Growing up playing the UFC fighting game on the Dreamcast, Frank Shamrock was my favorite MMA fighter, and this history/tribute to him was great. Other Fun Reads “The Hardest Part Of History To Tell Is How It Felt“ by Craig Fehrman at Defector “Unmasking the Sea Star Killer“ by Craig Welch at bioGraphic “What Could Save the Industry? Fin-Syn“ by Richard Rushfield in The Ankler Alex Rollins Berg in Underexposed on movie bumpers, pillow shots, Disney trash cinema, cult films, and Casablanca. David H. Montgomery in YouGov’s The Surveyor on punctuation marks, condiments, dinosaurs, and comic strips and kids media. “How Medium finally pivoted its way to profitability“ and “Why the best journalists on YouTube are all former Vox employees“ by Simon Owens in Simon Owens’s Media Newsletter “It’s Not Just You, Netflix Shows Have Gotten Slightly Shorter: Here’s What the Data Says“ by Kasey Moore at What’s on Netflix “Numlock Awards: How Diane Warren became the biggest loser in Oscar history“ by Nathaniel Rakich and “Numlock Awards: The Oscar Bait era is over. The Oscar Chum era is here.” by Walt Hickey & Michael Domanico at Numlock Awards

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Jul 3 • 2:38 PM EDT • Entertainment • entertainment.substack.com
Clarity Narrative Introduces Service to Help Businesses Address the Hidden Cost of AI Misrepresentation

Photo Courtesy of Microsoft EdgeSOUTHINGTON, Conn., July 03, 2026 (GLOBE NEWSWIRE) -- Realized Solutions, Inc., the Connecticut technology firm ...

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Jul 3 • 12:06 PM EDT • Business • markets.businessinsider.com
Oba Corporation Introduces Mega Sardines to Azerbaijan Market to Address Regional Health Trends

Mega Sardines, in its distinctive upright vertical can, is already appearing on Oba shelves BAKU, Azerbaijan, July 03, 2026 (GLOBE NEWSWIRE) -- ...

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Jul 3 • 12:00 PM EDT • Health • markets.businessinsider.com
Mamdani delivers address to mark nation's 250th birthday

Mamdani’s 15-minute speech covered a range of topics about America.

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Jul 3 • 11:55 AM EDT • Politics • ny1.com
Nintendo President Says The Pokémon Company Will 'Take Measures' to Respond to Widespread Card Scalping Issues

Nintendo's president has been asked to address the current state of Pokémon card shortages and scalping, which many fans feel is worse than ever, despite 10 billion cards being printed last year.

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Jul 3 • 10:21 AM EDT • Technology • ign.com
Hakeem Jeffries addresses Democratic Party divisions, says Trump is the bigger issue

On the eve of America's 250th birthday, NPR's Michel Martin asks House Minority Leader Hakeem Jeffries of New York about the Democratic Party's midterm future.

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Jul 3 • 8:53 AM EDT • Politics • npr.org
High-Signal Publisher
“He Didn’t Need to Die.” How an Immigration Detention Center Repeatedly Failed to Address a Mental Health Crisis.

Geraldo Lunas Campos repeatedly raised concerns about his mental health before he died at Camp East Montana. Records paint a portrait of how the Texas facility’s staff failed to adequately respond.

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Jul 3 • 5:00 AM EDT • Health • propublica.org
Legislative efforts to address chronic absenteeism in New York continue

Chronic absenteeism is defined as a student missing 10% or more of the school year.

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Jul 2 • 8:04 PM EDT • Politics • spectrumlocalnews.com
Sony Discusses Potential Future PlayStation Plus Price Hikes

Sony says it continues to balance value and pricing for PlayStation Plus, addressing the possibility of future subscription increases.

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Jul 2 • 6:57 PM EDT • Technology • insider-gaming.com
Two Women Arrested in Millcreek Township Illicit Massage Business Raid - The Institute to Address Commercial Sexual Exploitation

On June 16, law enforcement executed a search warrant on Magic Health Massage Spa in Millcreek Township in an ongoing effort targeting illicit massage businesses in Erie County. Law enforcement arrested two New York women who allegedly lived at the … Read more about Two Women Arrested in Millcreek Township Illicit Massage Business Raid »

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Jul 2 • 4:28 PM EDT • Business • cseinstitute.org
House panel explores direct health contracting to lower costs

The House Education and Workforce Subcommittee on Health, Employment, Labor and Pensions July 1 examined whether direct health care contracts between employers and providers could help address rising health care costs.

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Jul 2 • 11:02 AM EDT • Health • aha.org
Letter to a Climate Sceptic: What Science Would Like to Tell You

Dear climate sceptics, I address you this evening not as a judge, nor as a lecturer, but as a man who has spent his life watching the sky and listening to what it has to tell us. I come to you with my…

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Jul 2 • 7:44 AM EDT • Science • dailykos.com
Bonus 236: A Term of Self-Inflicted Wounds

Within minutes of the Supreme Court handing down the birthright citizenship ruling on Tuesday and rising for its summer recess, its defenders were pointing to that decision (alongside the late-arriving mail-in ballots ruling on Monday and the tariffs ruling from February) as decisive proof that the Court really is “above politics,” and that criticisms of the justices for behaving more like politicians in robes than like judges are thus unfair. For a particularly thoughtful version of this claim, see Professor Will Baude’s opening response to the latest New York Times written roundtable about the Court with Baude, Professor Kate Shaw, and me. In that roundtable, I already offered one of the two major arguments against this thesis—that it’s an assessment of the numerator without regard to the denominator, and that a full account of the Court’s behavior throughout OT2025 suggests that the Court behaved even more politically during the current term than during even the previous (highly politicized) one. Just to take one of many data points, last term (OT2024), there were six rulings in argued cases in which all six Republican-appointed justices were in the majority and all three of the Democratic appointees were in dissent (along with a slew of such rulings on the emergency docket). This term, there were … 13. (Along with two 6-3 summary reversals and 10 rulings on the emergency docket from which the three Democratic appointees all dissented.) Today’s bonus issue addresses the flip side of that coin. In particular, below the fold, I identify four different moments in which the justices could have acted in ways to specifically defuse charges of political behavior—and opted instead to lean all the way in. As much as end-of-term narratives focus on what the Court did, and on the takeaways from individual rulings, consider today’s post an attempt to identify opportunities that the Court missed, as well. At least in the examples discussed below, by opting for the outcome that made the Court look more transparently political, the Court inflicted a series of (unnecessary) credibility wounds on itself. For those who aren’t paid subscribers, we’ll be back Monday with our regular coverage of the Court. For those who are, please read on.

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Jul 2 • 7:15 AM EDT • Politics • stevevladeck.com
🌈 The political fatigue of doing feminist and queer research in anti-gender times

Anti-gender politics does not only attack rights. It attacks the knowledge that makes those rights intelligible. Massimo Prearo argues that anti-gender politics is an epistemic conflict as much as a political one. This conflict generates political fatigue among researchers engaged in feminist and queer work. We must address such fatigue through distance, care and collective reflection

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Jul 2 • 6:01 AM EDT • Politics • theloop.ecpr.eu
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Computer science society creates new research integrity role to address case backlog

AndreyPopov/iStock Over the last five years, the Association for Computing Machinery has been dealing with a rapid rise in allegations of research misconduct that have created a backlog of cases to…

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Jul 2 • 6:00 AM EDT • Science • retractionwatch.com
Red Wings’ biggest offseason business remains, but their outlook looks bleak

The Red Wings addressed two of their biggest needs, but the strength of the Atlantic Division makes for a grim landscape.

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Jul 1 • 8:51 PM EDT • Business • nytimes.com
WHO, Member States discuss expanding South-East Asia Emergency Health Fund SEARHEF

With climate-related disasters, disease outbreaks and other health emergencies becoming more frequent and complex across South-East Asia, WHO and Member States today discussed measures to strengthen and expand the South-East Asia Regional Health Emergency Fund (SEARHEF) to ensure countries have rapid access to life-saving support when crises strike. "Health emergencies are becoming more frequent, more complex and more costly. Countries need rapid, flexible financing that can be mobilized immediately when lives are at risk. SEARHEF represents regional solidarity in action, enabling Member States to support one another when emergencies strike," said Dr Catharina Boehme, Officer-in-Charge WHO South-East Asia Region. She was addressing the Fifteenth Meeting of the Working Group on the Governance of SEARHEF.

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Jul 1 • 8:00 PM EDT • Health • who.int
Apple's Hide My Email feature has a bug that's been exposing real email addresses, researcher claims

Research appears to reveal a bug that could render the feature effectively useless.

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Jul 1 • 3:18 PM EDT • Technology • techcrunch.com
CHAMP Initiative Combines Climate Science and Storytelling to Address Urban Heat

As summer temperatures climb, so does the risk of extreme heat—now recognized by the National Oceanic and Atmospheric Administration as the leading cause of weather-related deaths in the United States. In cities such as Camden, where buildings, pavement, and other infrastructure trap heat and create higher temperatures than surrounding areas, understanding the impacts of urban […]

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Jul 1 • 2:55 PM EDT • Science • sebsnjaesnews.rutgers.edu
Gift From Phil Hochberg ’61 Combines His Passion for Newhouse, Sports and DC

A prominent lawyer, Phil Hochberg is also well-known in Washington, D.C., as a former MLB, NFL and college public address announcer.

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Jul 1 • 10:01 AM EDT • Sports • newhouse.syracuse.edu
Apple Hide My Email bug allows 100% of real email addresses to be discovered

A privacy flaw in Apple’s Hide My Email feature means that your real email address can be discovered. A security...

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Jul 1 • 9:24 AM EDT • Technology • 9to5mac.com
Lawmakers takes another crack at easing privatization of youth sports

House bipartisan committee addresses private equity’s "vertical integration" that has youth sports costs soaring. What might come out of the hearing?

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Jul 1 • 9:00 AM EDT • Sports • usatoday.com
Apple ‘Hide My Email’ Vulnerability Reveals Peoples’ Real Email Addresses

”Hide My Email users deserve to know that it may be possible for attackers to discover their hidden email addresses,” the person who reported the issue said.

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Jul 1 • 6:00 AM EDT • Technology • 404media.co
219 Taproom in Chesterton unveils their JULY LINE-UP for Entertainment

Stop by 219 TAPROOM in Chesterton for WONDERFUL Food, Service, Fun and Entertainment. Check out their Family-Friendly Atmosphere and stay up to date with the latest by LIKING their FACEBOOK page. Service options: Outdoor seating · Live music · Trivia night. Their address is 109 S 3rd St, in Chesterton. Call (219) 728-1381. #wims #whfb #chesterton #duneland

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Jul 1 • 1:35 AM EDT • Entertainment • wimsradio.com
South Fulton leaders hopeful new investment will address crucial healthcare gap on Atlanta's south side

For decades, residents and officials alike have raised the issue regarding limited access to hospitals and specialty care in South Fulton. Now, county leaders and health officials are earmarking funds to address the situation.

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Jun 30 • 5:17 PM EDT • Health • cbsnews.com
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Initiatives To Bridge The Digital Divide For Small Business

Nourish + Bloom Market exemplifies the way small businesses can harness technology to address community needs, and how industry partners such as AT&T can support them.

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Jun 30 • 2:37 PM EDT • Business • forbes.com
Supreme Court agrees to review ban on AR-style semi-automatic rifles in major Second Amendment case

The Supreme Court announced Tuesday that it will decide whether cities and states may ban people from owning AR-15 rifles and similar semiautomatic weapons, taking up a major Second Amendment dispute that it had previously declined to address.

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Jun 30 • 12:16 PM EDT • Politics • cnn.com
Stein creates bipartisan commission to address rising North Carolina health care costs

Gov. Josh Stein signed an executive order Tuesday creating a bipartisan commission to recommend ways to lower health care costs, improve transparency and expand access to care across North Carolina.

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Jun 30 • 12:05 PM EDT • Health • wral.com
WATCH LIVE: Long-missing Rep. Tom Kean Jr. expected to address mysterious absence on House floor
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Jun 30 • 9:43 AM EDT • Politics • pbs.org
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Vatican Observatory addresses one of science’s greatest enigmas: quantum gravity

A conference addressed the subject of quantum gravity with regard to the incompatibility of quantum mechanics with general relativity, presenting a challenge for researchers to propose solutions.

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Jun 30 • 7:00 AM EDT • Science • ewtnnews.com
Newsom signs bill to give judges more power to deny mental health diversion

California Gov. Gavin Newsom has signed a bill to overhaul the state's mental health diversion program. Assembly Bill 46, authored by Stephanie Nguyen, D-Elk Grove, addresses concerns about public safety and accountability.

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Jun 30 • 1:18 AM EDT • Health • kcra.com
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Developer addresses community concerns around Franklin youth sports complex project

The project, proposed by developer BLVD Capital, would transform Brownland Farm, a 233-acre property on Hillsboro Road just outside downtown Franklin, into “The Banks at Brownland.”

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Jun 29 • 11:48 PM EDT • Sports • wsmv.com
ERISA’s Important but Limited Role in Health Care Cost Containment

Executive Summary Rising health care costs have brought renewed attention to the Employee Retirement Income Security Act of 1974 (ERISA) as policymakers and advocates look for new ways to address increasingly expensive employer-sponsored coverage. Leveraging requirements under ERISA appears attractive because other cost-containment efforts have had limited success, making the statute seem like a potential […]

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Jun 29 • 8:00 PM EDT • Health • americanactionforum.org
Key Trends in Health at the Milken Institute Global Conference 2026

The 29th annual Milken Institute Global Conference convened leaders from across health, science, business, finance, and policy to address the most pressing chal

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Jun 29 • 8:00 PM EDT • Health • milkeninstitute.org
RWJBarnabas Health Invests $1.7 Million to Support Community Health Initiatives in Hudson County

On June 16, 2026, RWJBarnabas Health announced a combined $1.7 million investment to support local organizations working to address barriers to care, food insecurity, and economic stability among underserved communities in Jersey City and Hudson County.

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Jun 29 • 3:20 PM EDT • Health • rwjbh.org
KARE 11 Spotlights Mental Health at USA Games through Special Olympics Strong Minds

KARE 11 visited Special Olympics Strong Minds to hear from USA Games athletes and volunteers about how the screening aims to address the mental health disparities faced by people with intellectual and developmental disabilities.

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Jun 29 • 1:52 PM EDT • Health • specialolympics.org
Cleveland Clinic Tackles Hunger, Housing and Maternal Health

In 2025, our teams continued to address critical social drivers of health, expand access to care and resources, and build stronger, healthier communities.

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Jun 29 • 9:00 AM EDT • Health • newsroom.clevelandclinic.org
OpenAI sets up 'warroom' to fix Codex limit issues

OpenAI investigates Codex's usage limit depletion that's impacting some users. The company has reset user caps to address the problem.

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Jun 29 • 8:51 AM EDT • Business • businessinsider.com
UC Berkeley is establishing the Nancy Pelosi Institute to address democracy's challenges

Former House Speaker Nancy Pelosi and the University of California, Berkeley, are partnering to form a new nonpartisan academic institute they say will be dedicated to strengthening democracy

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Jun 29 • 8:12 AM EDT • Politics • washingtonpost.com
UC Berkeley is establishing the Nancy Pelosi Institute to address democracy's challenges

Former House Speaker Nancy Pelosi and the University of California, Berkeley, are partnering to form a new nonpartisan academic institute they say will be dedicated to strengthening democracy.

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Jun 29 • 8:06 AM EDT • Politics • news4jax.com
WGU’s flexible, skills-first pathways are bridging Detroit’s talent gap

Discover how skills-first education is helping employers address workforce shortages across Southeast Michigan.

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Jun 29 • 5:00 AM EDT • Business • crainsdetroit.com
Colorado’s regulations should address policy challenges only as truly needed

As Colorado approaches its 150th birthday, we should remember its first 100 years were characterized by repeated boom-and-bust economic cycles. Dependence on mineral extraction and agricultural commodity prices was subject to the volatility of these markets. In 1972, as I arrived in Denver with Ma Bell, 40,000 metro households were waiting for dial tone since […]

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Jun 29 • 2:45 AM EDT • Politics • coloradopolitics.com
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial

Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to

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Jun 28 • 3:45 PM EDT • Health • astrazeneca-us.com
State Sen. Josh Becker unveils "Wartime Price Gouging Prevention Act"

California Sen. Josh Becker has introduced a bill to empower the state attorney general to investigate price gouging during wartime emergencies, addressing what he says is a significant financial burden on Californians.

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Jun 28 • 11:25 AM EDT • Politics • kcra.com
Q&A: Why humanitarian aid is crucial to stopping the Ebola outbreak

Health officials say the Ebola response cannot succeed without addressing the humanitarian crisis.

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Jun 28 • 11:01 AM EDT • Health • aljazeera.com
Community baby shower in Landover aims to address disparities, promote healthier lifestyles

This weekend in Prince George’s County, people came together for a community baby shower aimed at promoting healthier lifestyles among Black and Brown families across the DMV. With a lot of energy and laughter in the room, hundreds of people gathered at Prince George’s Sports and Learning Complex in Landover. The free event offered support for expecting mothers and parents…

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Jun 27 • 7:56 PM EDT • Health • nbcwashington.com
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Ryman Hospitality Addresses Reports About Opry Entertainment Group

Ryman Hospitality Properties addressed recent media reports regarding its Opry Entertainment Group business.

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Jun 27 • 8:14 AM EDT • Entertainment • pulse2.com
Steelers’ Drew Allar Addresses Rookie Role Behind Aaron Rodgers

Pittsburgh Steelers quarterback Drew Allar spoke out on his place behind Aaron Rodgers on the team's depth chart entering 2026 NFL training camp. The post Steelers’ Drew Allar Addresses Rookie Role Behind Aaron Rodgers appeared first on HEAVY.

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Jun 27 • 3:40 AM EDT • Sports • sports.yahoo.com
People complete workforce pilot program designed to address maternal health inequalities
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Jun 26 • 8:00 PM EDT • Health • 13wham.com
KATSEYE addresses speculation over Manon's future with group

KATSEYE is asking fans for patience as Manon Bannerman's health-related hiatus stretches into its fifth month.

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Jun 26 • 6:52 PM EDT • Entertainment • centraloregondaily.com
Deb Haaland Outlines Small Business Agenda in Address to Albuquerque Chamber

Native Vote 2026 Democratic gubernatorial nominee Deb Haaland (Laguna Pueblo) on Thursday outlined her vision for making New Mexico more welcoming to entrepreneurs and small businesses during an address to the Greater Albuquerque Chamber of Commerce, pledging to reduce regulatory barriers while investing in education, public safety, and economic development. Drawing on her own experience […]

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Jun 26 • 3:24 PM EDT • Business • nativenewsonline.net
Deb Haaland Outlines Small Business Agenda in Address to Albuquerque Chamber

Native Vote 2026 Democratic gubernatorial nominee Deb Haaland (Laguna Pueblo) on Thursday outlined her vision for making New Mexico more welcoming to entrepreneurs and small businesses during an addre...

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Jun 26 • 3:24 PM EDT • Business • yahoo.com
Netflix now requires every user profile to be tied to unique email address

Update began June 15 and will no longer allow you to share your login info.

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Jun 26 • 2:19 PM EDT • Technology • arstechnica.com
Ryman Hospitality Addresses Possible Sale of Opry Entertainment Group

Corporation officials say they are exploring the possible sale of a 70 percent stake in the entertainment entity, but there are no agreements in place and ‘no assurances any transaction will occur.’

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Jun 26 • 12:00 PM EDT • Entertainment • nashvillescene.com
ON Semi tanks 20% following Synaptics deal as CEO defends core business

The pivot into physical AI grows On Semi's addressable market by an additional $30 billion, the company said.

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Jun 26 • 11:39 AM EDT • Business • cnbc.com
Medical Debt Bills Advance, House Hears Behavioral Health Testimony

Several healthcare-related bills advanced in the Michigan Legislature during the week of June 22, including legislation addressing medical debt collections and behavioral health screenings.

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Jun 26 • 10:37 AM EDT • Health • mha.org
Joint statement – WHO/Europe and CCEE to collaborate on addressing health inequities and loneliness

WHO/Europe and the Council of Bishops’ Conferences of Europe (CCEE) officially signed a Letter of Intent on 23 June to establish a strategic partnership for promoting pan-European dialogue to reduce inequities, enabling every child and adult to live in health, safety and dignity.

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Jun 25 • 8:00 PM EDT • Health • who.int
Caitlin Clark made the WNBA bigger. It’s still playing small

The league’s paltry one-game suspension of Alyssa Thomas after her fist to Caitlin Clark's throat barely begins to address the problem.

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Jun 25 • 6:58 PM EDT • Sports • usatoday.com
Making Our Own Luck

We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.

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Jun 25 • 4:48 PM EDT • Science • goodscience.substack.com
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Senator Ron Wyden accuses US health agency of plan to deport more than 500 migrant children

Wyden says in a letter addressed to Robert F Kennedy Jr that HHS is preparing an ‘unprecedented legal framework’

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Jun 25 • 1:38 PM EDT • Health • theguardian.com
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