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Bladen Community College to host “So You Want to Start a Small Business” class and preview Pitch It Bladen 2027
The Small Business Center at Bladen Community College invites aspiring entrepreneurs to attend “So You Want to Start a Small Business” on Tuesday, Oct. 13, 2026, from 6:00 p.m. to 8:00 p.m. in Building 14, Room 104. This class will help participants explore what it takes to become an entrepreneur and take the first steps toward turning a business idea into reality.Participants will explore the entrepreneurial mindset and consider whether they have the interests, characteristics, motivation and willingness to take on the challenges of business ownership. The class will encourage attendees to examine their personal goals, expectations, strengths and readiness to pursue entrepreneurship.Attendees will also gain insight into the realities of starting and operating a small business, including the commitment, planning, decision-making and perseverance required to build a successful venture. Whether participants are just beginning to consider business ownership or already have an idea they want to pursue, this class will provide a foundation for determining their next steps.In addition to the class instruction, attendees will receive advance information about the upcoming Pitch It Bladen 2027 Business Competition, including the application form and details about the program. Individuals who are ready to move forward may submit their applications early and have the opportunity to receive advance acceptance into the program.Pitch It Bladen helps aspiring and emerging entrepreneurs develop their business ideas through structured instruction in business planning, financial management, cash-flow projections, marketing and operations. Participants work toward completing a business plan and preparing a business pitch, with the opportunity to compete for cash prizes.Last year's Pitch It Bladen program demonstrated the value of investing in local entrepreneurs by helping participants strengthen their business knowledge, develop their business plans and prepare to present their ideas. The competition showcased the creativity and potential of Bladen County's small-business community and provided participants with practical tools to move their business goals forward.Building on that success, Pitch It Bladen 2027 will provide another opportunity for local entrepreneurs to gain knowledge, build confidence and take meaningful steps toward launching or growing a business.“The Small Business Center wants to help individuals make informed decisions about entrepreneurship before they take the leap into business ownership,” said Theresa Dennison, Small Business Center director, in a press release. “This class gives participants an opportunity to evaluate whether entrepreneurship is right for them while also introducing them to Pitch It Bladen 2027 and the resources available to help them succeed.”Registration: Visit www.ncsbc.net and search for the class by name, or contact the Small Business Center at 910-879-5572 for additional information.
Edison's Entertainment Complex Female Athlete Of Month: Jess Sever Has Made Important Contributions To Edwardsville Girls Flag Football Team
Edwardsville sophomore Jess Sever has five touchdowns as the undefeated Tigers girls flag football team advances in the IHSA postseason.
The Packers’ easy portion of the schedule is over
Moving forward, Green Bay Packers’ schedule is much tougher than the first four weeks of the 2026 season
Myles Lewis-Skelly Nominated for 2026 Golden Boy Award
Myles Lewis-Skelly is Arsenal's only representative among the 25 finalists for the 2026 Golden Boy award.
Chelsea Duo Nominated For 2026 Golden Boy Award
Two Chelsea stars headline the 2026 Golden Boy awards for a second consecutive season as the Blues hunt for a winner of the award for the first time.
Fantasy Football Waiver Wire: 9 Must-Adds for Week 5
Week 4 on the 2026 NFL schedule is nearly in the books, and fantasy football managers can start pivoting toward Week 5. It also marks the start of a particular bane of fantasy managers' existence for the year: bye weeks. Just two teams, the Carolina Panthers and Kansas City Chiefs, are idle in Week 5, …
180-employee Manatee HVAC, plumbing company names new CEO
Arctic Air Home Services makes a leadership change as it aims toward growth in the region.
How a controversial camera system is monitoring mental health patients
The Lampard Inquiry started back in September 2024 and I remember going to the first hearing in Chelmsford. Subscribe The bereaved families made placards of their loved ones, they stood outside in silence and then laid flowers to mark the moment. Now, two years on, in a process meant to last another two years, there’s been a development. Last week, we were told the chair, Baroness Lampard, pictured below, could be looking at making interim recommendations. Throughout the process, she has remarked that although this inquiry is looking at almost 2,000 people who were under the care of Essex mental health services from 2000-2023 when they died, the findings could have national implications for other trusts. ‘Records 24 hours a day in patient’s bedroom’ So why has this happened? One system that the inquiry is going to take a closer look at is a controversial monitoring system called Oxevision. It monitors some vital signs of patients remotely by using a camera placed in a room. It’s used by 40% of NHS mental health trusts. But campaigners, particularly the group Stop Oxevision, have asked for this technology to be removed from mental health wards as soon as possible. I spoke to a member, Hat Porter, today and they described to me what they thought this technology did and explained their concerns: “It records 24 hours a day and it’s located in a patient’s bedroom, which is obviously somewhere you’d usually expect to be a private place. “Our concerns are that the use of the technology has been has been kind of implemented as a substitute for proper in-person support, that it’s kind of over relied on and that there’s a lot of misunderstandings and that the presence of a camera, which has often been used without people’s consent, sometimes without even their knowledge, that that has a really big impact on privacy, dignity and human rights.” ‘Not sufficient’ I put it to them that the company behind Oxevision would dispute their claims about consent and in videos I’ve seen online from NHS trusts, they make it clear that the technology is complementary to trained staff and not a replacement. [ ](https://channel4news.substack.com/p/the-nottingham-inquiry-what-lessons) [ How the Nottingham inquiry shines a spotlight on other key mental health care failings ](https://channel4news.substack.com/p/the-nottingham-inquiry-what-lessons) Victoria Macdonald · Feb 12 [ Read full story ](https://channel4news.substack.com/p/the-nottingham-inquiry-what-lessons) A team of lawyers has been working on the inquiry and with bereaved family members who have concerns about this technology. I spoke to solicitor Priya Singh, from Hodge Jones & Allen, who made the point that questions usually asked by nurses would be missing from using devices like this. “It’s not sufficient to say, oh, the patient is moving around. Somebody must go in and say, are you okay? Are you distressed? Do you want help? Is there anything I can do? Share Channel 4 News “How are you spending your time? So I think a lot of our families cannot see the function of it when ultimately the patient should only really be observed when they’ve been prescribed to be observed, they can be observed more, but that more should really be happening face to face.” The Chair will hear evidence over the next two weeks and then a decision made after that, which could have national impact if she does decide this technology should be investigated or even removed. The Department of Health and Social Care said: “The Government is committed to ensuring that lessons are learned from the Lampard Inquiry to improve patient safety. “We are confident that the Inquiry will play an important role in identifying wider learnings for the health system following the tragic events in Essex and will contribute to improvements in patient safety.” We approached LIO Health, which runs Oxevision, for comment. Subscribe Share Channel 4 News Leave a comment
Now Open! APSA Teaching & Learning Conference Awards and Travel Grants | Deadline: November 16, 2026 -
Now Open! Apply for TLC Travel Grants & Awards Michael Brintnall Teaching and Learning Award APSA Award for Teaching Innovation | Travel Grants Deadline: November 16, 2026, 11:59PM ET Join political science teacher-scholars and students [...]
Nicklaus Children's Health System Honored with Inaugural Champion for Children's Care Award from Joint Commission
/PRNewswire/ -- Nicklaus Children's Health System is pleased to announce that it has been recognized with the inaugural Champion for Children's Care Award from...
Now Open! APSA Teaching & Learning Conference Awards and Travel Grants | Deadline: November 16, 2026 -
Now Open! Apply for TLC Travel Grants & Awards Michael Brintnall Teaching and Learning Award APSA Award for Teaching Innovation | Travel Grants Deadline: November 16, 2026, 11:59PM ET Join political science teacher-scholars and students [...]
OSU Center for Health Sciences raises more than $800K for wellness center, scholarships
Oklahoma State University Center for Health Sciences hosted its first Orange Impact event Thursday and raised more than $800,000 toward a new wellness center an
Pokémon GO Halloween 2026: Part One
Pokémon GO’s Halloween 2026 Part One event runs from October 27 at 10:00 a.m. to November 1 at 10:00 a.m. local time, bringing three new costume Pokémon: Pikachu wearing a hat and capelet, Zubat wearing a top hat, and Sinistea wearing a bow! Expect spooky wild encounters, costume raids, and trick-or-treat surprises that can reward […]
Houston high school football: Week 6 takeaways and top performers
Landen Williams-Callis is passing Texas high school football legends, Friendswood is off to its best start in 16 years, Bridgeland is surging toward another district title run.
Greenfield Business Association distributes inaugural Buzz Awards
Greenfield Business Association held its first Buzz Awards at Four Phantoms Brewing Co., celebrating local shops like Hope & Olive and Freedom Cafe.
Mental health stigma in Japan may deter care
A UC Riverside–led study of mental health stigma in Japan has found a striking gap between the need for treatment and people's willingness to seek it, with high levels of social distancing toward people ...
Serie A talent in Golden Boy Award 2026 nominees
The nominees for the 2026 Golden Boy Award have been announced, including Serie A talent Kerim Alajbegovic of Juventus, Roma’s Rodrigo Mora and Franco Mastantuono of Fiorentina.The trophy is for the...
RWJBarnabas Health President and CEO Mark E. Manigan Named 2026 NJBIZ Executive Excellence Honoree
Mark E. Manigan, President and Chief Executive Officer of RWJBarnabas Health, the largest, most comprehensive academic health system in New Jersey, has been named a 2026 Executive Excellence honoree by NJBIZ, recognizing his leadership and impact on New Jersey’s health care landscape. Mr. Manigan and the other honorees will be recognized by NJBIZ at an awards ceremony taking place today.
Stock up/stock down for Kentucky after beating South Carolina
The Kentucky football team got a comeback win over South Carolina this week. Here's whose stock is soaring, and whose isn't afterwards.
Philanthropy: Q+A with William Ahmanson
William Ahmanson is the president of the Ahmanson Foundation, which financier Howard F. Ahmanson and his wife, Dorothy Grannis Ahmanson, established in
Nobel medicine prize goes to 3 scientists for research into brain activity
The Nobel Prize in medicine has been awarded to three scientists whose work led to a tool that uses light to help unravel how the brain works
Silly Dillys Wins $30,000 at RISE Up Harlingen Business Pitch Competition
Silly Dillys captured first place and a $30,000 award at the third annual RISE Up Harlingen Business Pitch Competition, leading a group of local entrepreneurs receiving financial support to develop and expand their businesses.
FSU data scientist receives NSF CAREER Award to develop AI model to analyze complex numerical data at scale
A Florida State University artificial intelligence and data scientist has earned one of the most prestigious early career faculty awards to develop a new
Capitals’ Alex Ovechkin suddenly announces retirement plans
The 41-year-old forward has the end in sight.
🚨 Golden Boy 2026: the official list of 25 finalists
The whiz kids.From 100 to 25. On Monday evening, the official list of 25 finalists for the 2026 Golden Boy award was unveiled by Italian sports outlet Tuttosport, which organizes the event and the awa...
3 scientists share Nobel Prize in Physiology and Medicine for work in optogenetics
The Nobel Foundation awarded its prize in physiology and medicine Monday to three scientists who researched how nerve cells affect the brain.
What does Spain's snap election mean for the EU?
Spain's snap election on 29 November could cost progressive European forces their last government in a large member state, tilting EU power towards the right and pushing socialists into opposition mode.
Supreme Court rejects Roy Moore's push to restore $8.2M defamation verdict awarded to him
The U.S. Supreme Court has rejected Roy Moore’s push to restore an $8.2 million defamation verdict awarded to him over a 2017 Senate ad | KNSS Radio
Nobel for medicine awarded to 3 scientists for work that helps map the brain
A method that controls nerve signals with light, developed by an American and two Germans, has provided greater understanding of Alzheimer’s and is used in efforts to restore sight.
Spurs' Harris questionable for regular-season opener after straining left calf
The 6-foot-8 power forward will be reevaluated following the team’s five-game preseason schedule.
2026 Outstanding Women in Business
The 18th annual Outstanding Women in Business awards recognize a dozen well-accomplished professionals from across the region and in many industries who go above and beyond. The committee selected the winners from more than 80 nominations, all of whom were worthy. The criteria evaluated each nominee’s professional achievements, community impact, ability to break the glass ceiling and mentorship of other professionals, particularly women. In addition to profiling these women in the following pages, the Worcester Business Journal will celebrate this year’s Outstanding Women in Business at a special luncheon on Oct. 28 at the College of the Holy Cross. To join the celebration of these exceptional women, visit WBJournal.com and register. – Mark Conti, editor This Year’s Judges Worcester Business Journal considered 54 Central Massachusetts professionals for the 2026 Outstanding Women in Business awards, based on 83 nominations. These nominees were independently evaluated by two volunteer judges, who scored each on their professional achievements, community contribution and mentorship of young professionals. Samantha P. McDonald is a partner at Bowditch. She is an experienced, client-focused real estate lawyer, concentrating on business and real estate property law. She has been recognized as a WBJ Power 100 in the Class of 2026 and a “Top Women of Law” in Massachusetts Lawyers Weekly. Dr. Kavita Babu is chief medical officer and vice president of medical affairs at Heywood Healthcare, where she provides strategic and clinical leadership to advance high-quality, patient-centered care across the organization. She is also a member of the WBJ Outstanding Women in Business Class of 2025.
Michael Douglas on 'immortality,' Kirk Douglas and the memories he once avoided
Michael Douglas, the award-winning actor and producer, recently turned 82 and has released a memoir titled “One Helluva Ride.” | 830 WCCO
Michael Douglas on 'immortality,' Kirk Douglas and the memories he once avoided
Michael Douglas, the award-winning actor and producer, recently turned 82 and has released a memoir titled “One Helluva Ride.” | WWJ Newsradio 950
Yankees draw baseball’s hottest September arm in Game 2
The Yankees got one hit Saturday. Their reward for trying to even the series Monday is a starter who allowed […]
Delta Health Center Receives Funding
Delta Health Center, Inc. has received four awards totaling $4,660,331.59 through the Mississippi Rural Health Transformation Program, a state initiative funded by the Centers for Medicare & Medicaid Services. Governor Tate Reeves announced the four RHTP awards on September 14, as part of 167 awards totaling more than $104 million statewide. The awards announced will […]
Delta Health Center Receives Funding
Delta Health Center, Inc. has received four awards totaling $4,660,331.59 through the Mississippi Rural Health Transformation Program, a state initiative funded by the Centers for Medicare & Medicaid Services. Governor Tate Reeves announced the four RHTP awards on September 14, as part of 167 awards totaling more than $104 million statewide. The awards announced will […]
Stanford Professor One Of Three Scientists Awarded The Nobel Prize In Medicine
Stanford professor Karl Deisseroth joins Peter Hegemann and Georg Nagel as winners of the 2026 Nobel Prize in Physiology or Medicine for their work on optogenetics.
Business confidence held in negative territory in September
Business confidence ticked upwards among Massachusetts employers in September but sentiment remained in negative territory and torn between the impacts of growth and rising costs.
The Daily Mauling: 10/5/26
Kansas Jayhawks News It’s official, Melvin Council, Jr is coming back to Kansas Jalon Daniels got his first NFL start this weekend. It didn’t go especially well, but he vows to use the lessons he learned moving forward What did we learn from the 55-0 drubbing of MTSU? The LJW weighs in The Topeka Capitol-Journal […]
Physician Assistant Brandon Guth Earns Reid Health’s Advanced Practice Provider of the Year Award
Brandon Guth, PA-C, a physician assistant with Reid Medical Associates, is the second recipient of Reid Health’s Advanced Practice Provider (APP) of the Year Award for his commitment to clinical …
Nobel medicine prize goes to 3 scientists for research into brain activity
The Nobel Prize in medicine was awarded Monday to three scientists working on the mechanisms the brain uses to switch on, or off, the activity of individual nerve cells.
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Nobel medicine prize goes to 3 scientists for research into brain activity
The Nobel Prize in medicine was awarded Monday to three scientists working on the mechanisms the brain uses to switch on, or off, the activity of individual nerve cells.
Nobel prize in medicine 2026 awarded for research on mysteries of brain
Three scientists to share 12m Swedish kronor prize for their work on ‘light-gated ion channels and optogenetics’
Nobel Prize in medicine jointly awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel
The Nobel Prize in medicine was awarded Monday to Karl Deisseroth, Peter Hegemann and Georg Nagel for their research into light-gated ion channels and optogenetics. The prize money this year is 12 million…
American Deisseroth and Germans Hegemann and Nagel win 2026 Nobel medicine prize
Scientists Karl Deisseroth, Peter Hegemann and Georg Nagel won the 2026 Nobel Prize in Physiology or Medicine for "discoveries concerning light-gated ion channels and optogenetics," the award-giving body said on Monday.
German and US scientists win Nobel Prize in medicine for research on brain activity
The trio won the award for their discoveries concerning light-gated ion channels and optogenetics. This neurobiology tool has provided new insights into how we might treat blindness, depression, addiction and dementia.
German and US scientists win Nobel Prize in medicine
The trio won the award for their discoveries concerning light-gated ion channels and optogenetics.
Nobel Prize in medicine awarded to three scientists for their work ‘concerning light-gated ion channels and optogenetics’
The 2026 Nobel Prize for physiology or medicine has been awarded to three scientists – Karl Deisseroth, Peter Hegemann and Georg Nagel – for “their discoveries concerning light-gated ion channels and optogenetics.”
2026 Nobel Prize in Physiology or Medicine awarded to Karl Deisseroth, Georg Nagel and Peter Hegemann for work on optogenetics
Karl Deisseroth, Georg Nagel and Peter Hegemann developed optogenetics, which uses light and genetics to control individual cells
Rethinking discovery: how powerful screening tools are redefining the search for new medicines
In medicine discovery, identifying the right biological target has always been a critical and complex step. Today, the rise of powerful screening tools is fundamentally reshaping this process, creating a step-change in how we move from scientific hypotheses to transformative medicines. Advances in high-throughput screening, genomics and AI-driven analytics are enabling scientists to interrogate disease biology at unprecedented scale, bringing forward opportunities that were previously beyond reach.
Search for life on Mars takes major leap forward. Scientists detect longest organic molecules on planet to date | BBC Sky at Night Magazine
Scientists make discovery analysing rock pulverised for study by Curiosity rover. Largest organic compounds found on the Red Planet to date.
1 Pittsburgh school earns top scores for supporting community health
Pittsburgh Phillips K-5 was awarded for supporting the health of its students, staff and families, and other Pittsburgh schools also received honors.
Phillips 66 (NYSE:PSX): A Dividend Quality Pick With Solid Financial Health
Phillips 66 (PSX) earns 7/10 Dividend Rating with 28% payout, solid health, and attractive forward valuation, but margins and growth carry risks.
Soil Science and Sea Turtles: A UToledo Senior’s Case for Hands-On Learning
From clay soil to leatherback sea turtles, environmental science senior Rosalie Cufr is turning lab, field and international experience into a path toward sustainable agriculture.
Arsenal remain keen on Juventus forward Kenan Yildiz
Arsenal are interested in Juventus forward Kenan Yildiz, but face competition from Real Madrid and Bayern Munich for the highly rated Turkey international.The 21-year-old has been valued at around €...
The Nobel Prize week is kicking off in Stockholm with the medicine award
This year’s Nobel Prizes kick off with the awarding of the medicine prize at the Karolinska Institute in Stockholm.
The Nobel Prize Week Is Kicking off in Stockholm With the Medicine Award
STOCKHOLM (AP) — This year's Nobel Prizes will kick off on Monday with the awarding of the medicine prize at the Karolinska Institute in Stockholm. Last year, three scientists won the Nobel Prize in medicine for discoveries about how the immune system knows to attack germs and not our own bodies.
Wahine Mālama ʻĀina
Mālama ‘āina is the Hawaiian values-based practice of caring for, protecting and honoring the natural world. For this year’s Wahine issue, Hawaii Business Magazine recognizes five women doing vital work to steward Hawai‘i’s land and ocean — from conserving culturally and ecologically significant sites and mitigating invasive pests to restoring coral reefs and revitalizing the traditional ahupua‘a system.
Penn State students win award for connecting health and environment through play
A series of games developed by a team of interdisciplinary Penn State students to help children in Iquitos, Peru, learn about the connections between human, animal and environmental health was recognized with a national American Society of Landscape Architects award.
Penguins Linked To $92.8 Million Star Forward
The discussion that fans of the Pittsburgh Penguins know is coming at some point is at least a full season away, but they won’t be able to ignore it much longer.The iconic duo of Sidney Crosby and Evgeni Malkin aren’t getting any younger, and both players are going to call it a career sooner rather […] The post Penguins Linked To $92.8 Million Star Forward appeared first on HEAVY.
Business owners offer rewards to those with information on Bissell Street shooting
South Bend Police are still looking for the suspect or suspects in the Bissell Street shooting from two weeks ago that killed three.The community is coming toge
Countries race to provide oral health care for all in 100-Day Sprint across Asia
Twenty Asian countries and areas across the WHO Western Pacific and South-East Asia regions vowed to strengthen essential oral health benefits as part of a “100-Day Sprint” initiative, during the 16th Asian Chief Dental Officers Meeting held from 27 to 29 September in Kota Kinabalu, Malaysia. The meeting marked the midpoint of the 100-day sprint bolstering support for countries to develop essential oral health benefit packages that can be integrated into national universal health coverage plans. Convened by the two WHO regional offices and the Malaysian Ministry of Health as the Secretariat, the meeting brought together national oral health leaders from 20 Asian countries, staff from all levels of WHO, WHO collaborating centres and other development partners. Participating countries and areas included: Bangladesh, Bhutan, Brunei Darussalam, Cambodia, China, Hong Kong (SAR) China, India, Indonesia, Japan, Lao People’s Democratic Republic, Malaysia, Maldives, Mongolia, Nepal, the Philippines, Singapore, Sri Lanka, Thailand, Timor-Leste and Viet Nam. Participants reviewed progress and refined proposals using the WHO Service Package Delivery and Implementation (SPDI) Platform. Countries conducted bottleneck analyses across four key areas: service delivery, workforce, access to essential medicines and health products, and health financing. They identified practical actions to address implementation challenges and refined proposed revisions to their national oral health benefit packages. “There is no health without oral health. Through the 100-Day Sprint, countries are advancing the implementation of the Western Pacific regional implementation plan on oral health and strengthening progress towards universal health coverage,” noted WHO Regional Director for the Western Pacific Dr Saia Ma'u Piukala. Participants identified bottlenecks and proposed workable solutions to strengthen access to essential oral health care through primary health care, sharing experiences and discussing how best to translate policy commitments into feasible and sustainable action at the country level. Malaysian Minister of Health Datuk Seri Dr Dzulkefly Ahmad highlighted the importance of prevention and primary health-care approaches to improve oral health: “Oral diseases can have lifelong consequences, yet many are preventable. By integrating essential oral health care into primary health care and promoting prevention in schools and communities, we can improve oral health across the life course.”The WHO team led by Dr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control of the WHO Western Pacific Region and national oral health leads from over 20 Asian countries visited the SK Pekan Putatan School, Sabah for school oral health programme including flouride mouth rinsing. © WHO / V. ChaudharyDr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control for the WHO Western Pacific Region, emphasized key collaborative roles WHO can play. “Oral diseases are the most common noncommunicable diseases, yet many can be prevented and treated through essential oral health services delivered at the primary health-care level,” she said. “By sharing experiences and using WHO tools such as the SPDI Platform, countries are accelerating progress towards universal health coverage for oral health.” “Integrating oral health into broader health services is essential for reducing inequities, expanding access and recognizing oral health as an integral component of overall health and well-being. The 100-Day Sprint provides an important opportunity to translate this commitment into practical action and ensure that quality oral health services reach all people, especially those most in need,” said Dr Suman Rijal, Director of the WHO South-East Asia regional Department of Healthier Populations and Noncommunicable Diseases. As host of the meeting, Malaysia showcased ongoing efforts to strengthen oral health care through primary health care and prevention-focused approaches, while providing a platform for countries across the two WHO regions to exchange experiences and accelerate progress towards universal health coverage for oral health. “WHO is encouraged by Malaysia's leadership in addressing the burden of oral diseases and advancing universal health coverage for oral health through practical, country-led action,” said Dr Rabi Abeyasinghe, WHO Representative to Malaysia, Brunei Darussalam and Singapore. Countries will continue to refine and figure costs for national oral health benefits during the remaining sessions of the 100 days. These efforts support implementation of the WHO Global strategy and action plan on oral health 2023–2030, while also helping to expand access to essential oral health services through stronger and more equitable health systems across the WHO Western Pacific and South-East Asia regions.______________For more information, or to arrange media interviews, contact: WHO Regional Office for the Western Pacific: wprocom@who.int WHO Regional Office for South-East Asia: SEMediaRelations@who.int
Patriots’ HC Raves About Drake Maye Compared to Josh Allen
The New England Patriots needed a response after a lopsided loss. Head coach Mike Vrabel received one from his quarterback against a division heavyweight. New England stunned the previously unbeaten Buffalo Bills 29-26 on Sunday, Oct. 4, and Vrabel placed Drake Maye in the same conversation as reigning NFL MVP Josh Allen afterward. “Gets us […] The post Patriots’ HC Raves About Drake Maye Compared to Josh Allen appeared first on HEAVY.
President awards state scholarships to distinguished figures in education and science
President Volodymyr Zelensky has awarded state scholarships to 16 distinguished figures in education. — Ukrinform.
Tom Brady owns up to awkward FOX Sports mistake during Eagles-Rams broadcast
During a FOX Sports NFL broadcast, Tom Brady accidentally muted his own headset by dropping a research board on his talkback button, causing a brief communication disruption in the booth.
Professor Renée Marlin-Bennett Receives International Studies Association (ISA) Award
Professor Renée Marlin-Bennett has received the 2027 Distinguished Scholar Award from the Science, Technology, and Art in International Relations (STAIR) section of the International Studies Association (ISA). The award celebrates scholars whose work and academic engagement have been highly influential in the study of science, technology, and art in International Relations and International Political Economy....
Carnell Tate's Breakout Overshadowed by Offensive Woes in Titans Loss
While Carnell Tate neared a career milestone, Cam Ward’s turnovers and a costly fumble stalled Tennessee’s momentum, gifting Derrick Henry a triumphant revenge game in Baltimore.
Should Bill Belichick Remain as North Carolina's Head Coach?
Should Bill Belichick stay with the North Carolina Tar Heels moving forward?
As Music Instrument Buyers Go Upscale, Fender Overhauls Online Experience
Fender is revamping its online presence amid a shifting market for musical instruments moving toward premium offerings, vintage sounds, and online sales and information.
James campaign scrubs some online elements of Trump support
Images of President Donald Trump were prominent on the campaign pages of Michigan Republican gubernatorial candidate John James before the Aug. 4 primary election, but afterward some of them have
Latino voters, souring on Trump, swing toward Democrats, new poll finds
The growing electorate played a critical role in Trump’s 2024 victory. Now, sentiment is dipping, particularly on economic issues, a new NBC/Telemundo poll finds.
Paly students combine science, compassion in children’s book
A group of Palo Alto High School students recently published a picture book — “The Brave Fuzzy” — that is geared toward getting young children excited for science.
California Politics 360 full episode
In Washington, D.C., President Donald Trump gathered leaders of major tech companies this week to talk about AI rules moving forward.
Florida Department of Health backs off vaccine exemption expansion
The Florida Department of Health is moving forward with its push to remove the requirement for four vaccines for children entering schools, but has dropped its attempt to expand exemptions for the immunization requirements.
Taylor Morrison snags 406 lots near TSMC's $265B Phoenix development
Homebuilders are shifting toward aggressive bulk lot acquisitions to lock down future inventory, with more to come.
Georgia woman business owner arrested on fraud charges
Other Mad Marketing clients have also come forward with allegations of fraud.
Julian Hall scores AGAIN as USMNT stun Mexico
By MLSsoccer staffJulian Hall keeps on rising to the occasion during his first US men's national team camp.Red Bull New York's star forward opened the scoring in the USMNT's 3-0 defeat of arch-rivals ...
Saudi Arabia to cancel Joy Awards, its answer to the Grammys, amid budget cuts, sources say
By Timour Azhari Oct 4 (Reuters) - Saudi Arabia is set to cancel next year's Joy Awards, its star-studded answer to the Oscars or the Grammys, as financial strain and the Iran war hit the country's nascent entertainment sector, two people with knowledg...
How to watch Dodgers vs. Braves NLDS Game 2
LOS ANGELES — The Dodgers will turn to Blake Snell in Game 2 of the National League Division Series, throwing another southpaw starter against the Atlanta Braves on Sunday night at Dodger Stadium. Snell, like Skubal, has won two Cy Young Awards in his career. But for Snell, his two Cy Young years (2018, 2023) […]
Should the Laver Cup Finally Bring Women Into the Mix?
Okay, so let’s try to make this Laver Cup hypothetical, civil, shall we? An obvious question hangs over the event called the Laver Cup. Why is it not called the Williams Cup? No, seriously now. Where are the women? For nine editions now, the formula has remained straightforward: six men from Europe, six from the …
Liverpool will offload struggling forward: Three clubs want January deal
Liverpool strengthened their attack with a couple of new forwards in the summer transfer window. Victor Munoz was onboarded after the Reds triggered the FIFA World Cup winner’s £34m Osasuna release...
Loveland Business Briefs for Oct. 4, 2026: Chamber awards dinner, Health Summit and more
News of Loveland area businesses for the week of Oct. 4.
Amazon exec says finding FDEs is challenging: 'These are unicorns'
An Amazon Web Services exec said that she's being selective in building out the firm's bet on forward-deployed engineers.
Rockstar Games Confirms Next Official GTA 6 Update for October 5
Grand Theft Auto fans looking forward to the long-awaited GTA 6 should circle their calendars for Monday, October 5.
Prisma doubles down on Urgent Care while Novant pivots to virtual visits
Two large South Carolina providers are pursuing opposite strategies. Prisma Health is acquiring 36 Urgent Care Centers from Novant Health, doubling its portfolio. Novant is moving toward virtual offerings.
Commerce awards grant to help Health Department speed up septic permit reviews
Awarded $70,000 to the Snohomish County Health Department to help it expedite reviews of on-site septic systems for new homes.
Luka Doncic praises Adou Thiero's 'insane' improvement
Lakers second-year forward Adou Thiero could be poised to make a sizable jump this season.
People in Business: SLSO appoints; CMIT names; UniGroup adds; Le Meridien appoints
Catch up on local business appointments, awards, and hires.
Zombie Run takes place in Poland
POLAND, Ohio (WKBN)- Runners laced their shoes for the annual Zombie Run in Poland Township. Participants took part in a 2k run and walk through Poland Township Park. Awards were given to the top three men and women in each age group. It’s been taking place for nearly two decades, bringing the community together. “One […]
Montreal-raised Juno-award-winning singer Sass Jordan dies at 63
Sass Jordan, the Montreal-raised rock singer whose career spanned nearly four decades, has died at 63.
Penguins Cut Veteran Forward Before Home Opener
The Pittsburgh Penguins are back in action on Saturday evening against the Montreal Canadiens, who make their first trip of the season to PPG Paints Arena in downtown Pittsburgh.It marks the return of hockey for the Penguins in front of their home fans for the first time since Game 5 of the Eastern Conference Quarterfinal […] The post Penguins Cut Veteran Forward Before Home Opener appeared first on HEAVY.
Grading the Grizzlies' Busy Offseason Before the 2026-27 Season
Memphis reshaped its roster around Cameron Boozer, Zach Edey and Cedric Coward while moving on from Ja Morant. The Grizzlies' offseason deserves high marks.
‘A Statement’ Review: Tom McCarthy’s Talky Climate Crisis Seriocomedy Is Light Entertainment That Hardly Rakes the Muck
New York Film Festival: The Oscar-winning writer/director turns his spotlight on a plushly appointed ensemble as the environmental stewards and scholars who tried to solve the climate crisis over one ...
Scientists just found a new way to make hydrogen from water
A new light-activated material can efficiently produce hydrogen from water without requiring an additional expensive metal catalyst. Researchers say its unusual sulfur-based chemistry could point toward cheaper and more practical ways to turn sunlight into clean fuel.
Liverpool given price, blockbuster £40m deal can move forward
Liverpool have been told the price. Now a blockbuster deal can move forward for one of the biggest talents in world football.Liverpool want to sign wonderkids. That's unbelievably clear to everyone wa...
Broward Health Offers Low-Cost and Free Mammograms Throughout October for Breast Cancer Awareness Month
MammoThon 2026 and “Beating Cancer Together” initiatives aim to remove cost as a barrier to early breast cancer detection for Broward County women Broward Health is marking Breast Cancer Awareness Month throughout October by hosting two community initiatives designed to make life-saving breast cancer screenings accessible to women regardless of insurance status or income. From October 1-31, the health system […]
Women's Fund to honor four with Dream, Achieve, Inspire awards
NEW HARTFORD — The Women’s Fund of Herkimer and Oneida Counties is celebrating its work supporting women and girls with a dinner at the Yahnundasis Golf Club, 8639 Seneca Turnpike,