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Synthesized Introduces Test Data Agent, Bringing Production-Faithful Validation to Enterprise AI Agents

London, GREATER LONDON, Aug. 18, 2026 (GLOBE NEWSWIRE) -- Synthesized, the AI-native test infrastructure company, today announced its Test Data ...

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Aug 18 • 4:00 AM EDT • Business • markets.businessinsider.com
American Airlines announces fleetwide upgrade with installation of seatback screens at every seat and increased premium seats across the narrowbody fleet

From 4K screens to high-speed Starlink Wi-Fi and more premium seats than ever, American ups the ante at 35,000 feet.

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Aug 17 • 8:00 PM EDT • Entertainment • news.aa.com
Kratom poison center cases have surged 6,500% in the U.S.

Kratom use and serious health problems linked to it have risen dramatically across the United States over the past decade. Poison center reports jumped from just 19 cases in 2010 to more than 1,200 in 2023, while severe outcomes—including life-threatening complications, disability, and death—also climbed sharply. Researchers warn that kratom can trigger seizures, abnormal heart rhythms, liver damage, and breathing problems, with risks potentially increasing when it is combined with other drugs.

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Aug 17 • 8:00 PM EDT • Science • sciencedaily.com
FDA heightens egg recall to reflect potential ‘serious adverse health consequences or death’

As of July, 26 people had been hospitalized due to Salmonella linked to the tainted eggs.

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Aug 17 • 4:27 PM EDT • Health • cidrap.umn.edu
Mike Johnson taunts Hakeem Jeffries for losing Dems' civil war 'in his own backyard'

Speaker Mike Johnson says Democrats are in an "open civil war" after DSA-linked candidates backed by Zohran Mamdani toppled Jeffries' allies.

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Aug 17 • 2:34 PM EDT • Politics • foxnews.com
Egg recall linked to salmonella upgraded to highest health risk level by FDA

The eggs were first recalled on July 22 by North Manchester, Indiana-based Midwest Poultry Services because they could be contaminated with salmonella.

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Aug 17 • 9:32 AM EDT • Health • newson6.com
AirPods Max 2 Discounted by $120 Across Amazon and Best Buy

Apple's AirPods Max 2 have hit $429.00 on Amazon this week, down from $549.00. This sale is available in two colors on Amazon, while Best Buy has all five models in stock at this low price. Note: MacRumors is an affiliate partner with some of these vendors. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.

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Aug 17 • 8:36 AM EDT • Technology • macrumors.com
McLaren McL 6GT Concept (2026)

McL 6GT name is inspired by McLaren's presence on track, as well as the foundations of McLaren's automotive journey. McL 6GT creates a direct link between these two realms...

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Aug 17 • 7:04 AM EDT • Technology • netcarshow.com
Cialis is an erectile dysfunction drug. Could it also help you live longer?

In some wellness circles, tadalafil is promoted as a longevity drug. There is evidence showing a link between it and a lower risk of death in men, but there are no well-controlled trials in humans.

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Aug 17 • 5:00 AM EDT • Health • npr.org
High-Signal Publisher
Big investors hunt for tomorrow's AI winners as capex angst fades

The rally in AI-linked stocks that marked the latest earnings season has shifted the focus of the AI investment story from whether Big Tech's spending spree will pay off to ​the kind of companies that will deliver returns over the longer term, investors say.

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Aug 17 • 1:01 AM EDT • Business • reuters.com
A 26-Year Study Linked 3 Midlife Health Risks to Nearly 13 Fewer Dementia-Free Years

Recent research identified an associational relationship between the three factors and cognitive decline.

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Aug 16 • 6:39 PM EDT • Health • inc.com
Age slower without dieting: this cultural habit stuns scientists worldwide - Futura-Sciences

Savoring Culture: A Surprising Health Ally Picture this: according to a British study involving more than 3,500 adults, a weekly dose of culture—be it through visiting museums, browsing in a library, humming along in a choir, or wielding a paintbrush—was linked to knocking one year off participants’ biological age, and...

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Aug 16 • 10:30 AM EDT • Science • futura-sciences.com
Beloved drink linked to less body fat and more muscle: study
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Aug 16 • 10:11 AM EDT • Health • nypost.com
Rogers and Chelsea's blueprint

It took Morgan Rogers only seven minutes to score his first goal in a Chelsea shirt in Saturday's 3-1 friendly win over Real Sociedad as he reacted quickest after Alex Remiro saved Joao Pedro's initial header. The £117m club record signing from Aston Villa initially looked sharp and linked well with Cole Palmer and Pedro in Chelsea's front three. Beyond Rogers, Joao Pedro has been the star of Chelsea's pre-season.

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Aug 16 • 8:06 AM EDT • Sports • sports.yahoo.com
Michael Smolens: Powerlink déjà vu on environment, energy and politics

Another proposed high-voltage transmission line through the desert is hotly disputed, much like one built years ago, but there are differences.

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Aug 16 • 8:00 AM EDT • Politics • sandiegouniontribune.com
This Week in Purple: Remembering Butch Huskey

Colorado Rockies news and links for Sunday, August 16th, 2026

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Aug 16 • 8:00 AM EDT • Sports • sports.yahoo.com
Musk’s headaches: meet China’s corporate matrix challenging his empire

From Tesla to SpaceX, Starlink and Neuralink, Chinese companies are giving – or trying to give – Elon Musk’s firms a run for their money.

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Aug 16 • 6:00 AM EDT • Business • scmp.com
Climbing stairs linked to dramatically lower risk of dying from heart disease
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Aug 16 • 12:05 AM EDT • Health • nypost.com
The No. 1 Hobby Most Highly Intelligent People Have, By A Psychologist

Brain games and chess don't build intelligence the way people assume. Here's the one everyday hobby psychology research keeps linking to a sharper mind.

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Aug 15 • 4:15 PM EDT • Technology • forbes.com
COVID-19 awakens dormant viruses — and one is linked to long COVID

COVID-19 can reactivate dormant viruses hiding in the body, including Epstein-Barr, cytomegalovirus, and several herpes viruses. One poorly understood viral family was strongly associated with long COVID and lasting disability, offering a potentially important clue to why some patients struggle to recover.

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Aug 15 • 8:00 AM EDT • Science • sciencedaily.com
Cardiac CT links air pollution to increased risk of coronary disease

Cardiac CT scans may give clinicians a way to visualize the effects of environmental exposure before cardiovascular events even occur.

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Aug 14 • 5:00 PM EDT • Business • cardiovascularbusiness.com
FDA upgrades egg recall linked to salmonella to highest health risk level
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Aug 14 • 3:57 PM EDT • Health • cbsnews.com
High-Signal Publisher
More than 3,100 cyclosporiasis infections reported in last week: health officials

The illness is linked to iceberg lettuce sourced from central Mexico and recalled by Taylor Farms.

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Aug 14 • 1:39 PM EDT • Health • 6abc.com
FDA in Mexico a month after linking Taylor Farms to cyclospora outbreak

Senior FDA official confirms that inspectors were on-site at the Taylor Farms processing facility and plan to be in the fields next.

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Aug 14 • 1:36 PM EDT • Health • washingtonpost.com
UK scientists use a 'gene gun' to grow pig protein in lettuce

Researchers got lettuce and tobacco to make myoglobin — a protein linked to many of meat's appealing traits.

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Aug 14 • 4:13 AM EDT • Science • yahoo.com
Sporting Lisbon Makes Luis Suarez Decision Amid Newcastle Transfer Links

Newcastle United continues to be linked with attacking reinforcements as Matthias Jaissle shapes his squad for the new Premier League season. One of the Magpies’ previously reported targets, Sporting Lisbon striker Luis Suarez, has resurfaced amid uncertainty in Portugal. Following some worrying developments surrounding his situation in the Iberian club, Portuguese outlet A Bola reports […]

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Aug 14 • 3:00 AM EDT • Sports • sports.yahoo.com
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West Virginia math and English scores top pre-COVID levels as science slips

West Virginia’s 2026 student assessments show math and ELA proficiency above pre-COVID levels, with math rising to 39% and ELA holding at 48%. Science slipped to 29%, while chronic absenteeism remained strongly linked to lower scores.

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Aug 13 • 8:43 PM EDT • Science • mybuckhannon.com
Beer, wine or liquor? Massive study reveals which was linked to lower death risk

Heavy alcohol use raised death risk by 24%, but wine at low levels was linked to lower mortality than beer or spirits in a UK Biobank study.

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Aug 13 • 2:34 PM EDT • Health • foxnews.com
AI needs science’s search history

“Actually, that’s where the gold is,” said Alasdair Russell, my graduate school friend who leads a pre-clinical genome editing group at Cambridge. He was talking about the winding road of science that is omitted from published papers. “When you’re discussing how to do the experiment, and why this way is better than another way, and what does the data really mean? I know what it shows, but what does it mean?” At RAAIS 2026, he described how his group has begun logging the twisting path of discovery as it happens, recording the verbal and written exchanges that normally disappear. Ideas become nodes in a living graph: they branch when a meeting produces two plausible experiments, merge when separate lines of evidence converge, and go dark when someone quietly stops pursuing them. In his implementation, one agent scores novelty, while another tries to learn “how scientists think and how they navigate through a complex world of data,” so that high-potential nodes can trigger deeper investigation. As frontier AI labs deploy agents toward scientific discovery, giving AI authentic scientific taste remains a trillion-dollar dilemma. The bottleneck is that the record we have kept for centuries of science might be insufficient to get us there. The experiments that never make the paper Peter Medawar, 1960 Nobel laureate and “father of transplantation,” asked in 1963 whether the scientific paper was a fraud, and answered yes: the form of the paper misrepresents the thinking that produced it. Sixty years on, the diagnosis is unchanged. A paper presents a clean progression from hypothesis to result to conclusion. Lost along the way are the unconventional theories, the abandoned or unaffordable methods, and the underwhelming and inconclusive data. It reads like a browser history with every dead end deleted: the ten open tabs, the four rephrased queries, the wrong turn down a subforum. All scrubbed, leaving one clean path from question to answer as the canonical path. What has changed since then is that the discarded material is now worth something. No high-impact journal wants these artifacts, but raw trial and error is the most likely source of the training data required to develop scientific intuition, or what researchers call taste. Earlier attempts to capture the discards were motivated by scientific integrity. The Journal of Negative Results in Biomedicine launched in 2002 to publish rigorous studies that disputed established models or exposed ineffective treatments. Its archive preserved negative conclusions after they had become papers, rather than the live alternatives and arguments that produced them. BioMed Central closed it in 2017, saying the mission had been served now that other journals publish null results. A less generous reading is that in fifteen years it published around 200 papers because almost nobody wants to read a negative result, let alone write one up when it will not count toward academic tenure. AI models are different. Even an uninteresting negative result can be useful, provided it is labeled. Earlier this year, Anthropic put a version of this to the test. The company pulled 129 decision points from real Claude Code sessions between January and March 2026, showed models the work up to a human detour, and asked what should happen next. Claude Mythos Preview beat the human choice 64% of the time, while Opus 4.5 managed 51%. The comparison was tilted toward the models because Anthropic deliberately chose moments where the human decision had room for improvement. On 127 further scenarios where the human action was already strong, the models improved on it only about 20% of the time. The study was possible because Anthropic’s researchers work inside a tool that logs by default. The reasoning, detours and outcome are produced in the same working environment. Biology has no equivalent. Its reasoning happens in hallways, at benches, in Slack threads and on whiteboards, while the outcome arrives weeks later somewhere else. The record has to emerge from the work itself. Ask scientists to reconstruct it afterwards and we’ll create another polished account. Subscribe A log is not a label Before any of this becomes training data, a negative result has to say what failed. The first paper published in the Journal of Negative Results in Biomedicine examined 234 negative studies across five leading medical journals. Only 30% discussed statistical power, and half clearly defined a primary outcome. Tell a model an experiment failed, without telling it whether the assay was underpowered, a reagent had degraded, or the hypothesis was simply wrong, and it will learn noise with confidence. Decision histories have a second missing label too. When a lab considers five experiments and runs one, only the chosen branch returns an outcome. The other four are experimental counterfactuals. Researchers call this the selective labels problem: the data reveal results only for the actions someone chose to take. Such a record can teach a model to imitate a lab’s taste, but it cannot establish that the taste was good. It also smuggles local constraints into general lessons. A lab that never ran cryo-EM because it did not own a microscope teaches a model that cryo-EM is rarely the right call. Alasdair’s nodes preserve the candidate set, which is the necessary first step. To be useful, each decision record needs six fields: The evidence available at that moment, and nothing that arrived later. The candidates considered, including the ones dismissed in a sentence. For each candidate: the expected result, the confidence attached to it, and the cost in time and money. The route chosen, and the reason. What happened next. How the evidence changed the scientist’s view. These must be timestamped before the outcome, because hindsight turns uncertainty into inevitability. Disagreement also has to survive. Averaging three scientists into one clean rationale reproduces exactly the information loss we are trying to fix. But there is an obvious failure mode here. Once decisions are logged and scored, people log for the record post-facto. Anyone who has watched an electronic lab notebook fill up with retrospective tidying knows how quickly a research tool becomes a compliance exercise. A record that costs a scientist ten minutes of honest reflection per decision is worth far more than one that costs an hour of performance. A publication initiative called Registered Reports offers a useful starting point. Here, researchers submit their rationale, methods and analysis plan for peer review before the data exist, and the journal commits in principle to publish if they follow the approved plan. Nature has now expanded the format across every field it covers. This approach to paper writing timestamps intent before the outcome, but it freezes one plan. A useful search history must also preserve how the plan changed, which alternatives were rejected, when, and on what evidence. Subscribe Run the runner-up Autonomous labs show what happens when decisions and outcomes are connected in a loop. Liverpool’s mobile robotic chemist ran 688 experiments over eight days in a ten-variable formulation space. A batched Bayesian search used each result to choose the next experiments and found photocatalyst mixtures six times more active than the starting formulations. Every completed experiment changed what the system did next. The robot optimized within a goal and search space that humans had already chosen. It did not decide which scientific question mattered. So what this work demonstrates is narrower, but still useful: a search history pays off when the options return standardized outcomes quickly. Open-ended biology is harder because branches can take weeks and the discarded alternatives may never be run. Some exploration therefore has to be bought. Where two branches are plausible and the stakes justify the cost, a lab should sometimes run the runner-up. Otherwise the record captures what today’s scientists usually chose and stays silent on what they systematically overlooked. A funder could ring-fence a small fraction of a grant for the branch not taken, provided that the decision record and the outcome are both deposited. That costs money, but so does having every lab rediscover the same abandoned path. Test whether taste transfers When it comes time to evaluate if our new AI system exhibits taste, the comparison should run across laboratories and fields. At selected decision points in a live research campaign, we should freeze the six fields: the evidence, the candidates, expected results, confidence, costs and the choice made. Experts then rank the options before the outcomes are known, and those outcomes are checked independently later. We could give models one of two diets - papers alone, or papers plus decision histories - and ask them to rank the next experiment on unfamiliar projects. Then, we score information gained per dollar and week, calibration, and how quickly weak branches are abandoned. If histories improve choices only inside the lab that produced them, they amount to useful organizational memory. If they improve choices on unfamiliar problems elsewhere, Alasdair’s group will have captured something science has never managed to write down: a transferable record of taste. Until that happens, a scientific search history is a promising record, not yet a training set.

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Aug 13 • 11:16 AM EDT • Science • press.airstreet.com
Brent Cooper to step down from NKY Chamber after 10 years 'connecting the dots'

Brent Cooper will step down as NKY Chamber president after his 10th year, ending a tenure focused on small businesses and regional advocacy.

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Aug 13 • 10:00 AM EDT • Business • linknky.com
Energy drinks are more popular than ever. Here’s what we know about the health risks.

Highly caffeinated energy drinks have been linked to heart problems, obesity and anxiety.

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Aug 13 • 5:00 AM EDT • Health • theexamination.org
Mikel Arteta highlights Arsenal’s one priority in transfer window

Arteta said the bar is high for Arsenal to find players who can improve their starting line-up, amid links with Atletico Madrid’s Julian Alvarez and Paris Saint-Germain’s Bradley Barcola

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Aug 13 • 4:10 AM EDT • Sports • sports.yahoo.com
Eagles Linked to Interesting QB Trade Proposal With NFC Opponent

The Philadelphia Eagles appear to be a contender in the NFC once again. Even after trading star wide receiver A.J. Brown, the team looks set up for success.With preseason about to begin, the Eagles will have some tough roster decisions coming up soon. One of those decisions will come at the quarterback position.Obviously, Jalen Hurts […] The post Eagles Linked to Interesting QB Trade Proposal With NFC Opponent appeared first on HEAVY.

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Aug 13 • 12:38 AM EDT • Sports • sports.yahoo.com
Weekly Entertainment Report: Live music and lively arts, Aug. 13-16

Music comes from the Greek word for "art of the Muses." Be inspired this weekend, find your muse.

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Aug 12 • 11:52 PM EDT • Entertainment • manchester.inklink.news
Birth order linked to 150 health conditions in study of 10 million American siblings

First-born children showed higher rates of autism, ADHD and food allergies, while second-born siblings faced more substance use disorders and migraines.

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Aug 12 • 8:14 PM EDT • Health • foxnews.com
Pokémon FireRed Version and Pokémon LeafGreen Version Link with Pokémon HOME This October

Complete the Pokédex to partner up with a new Pokémon, encounter new Legendary Pokémon, and more.

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Aug 12 • 8:00 PM EDT • Technology • pokemon.com
Section IV Football Media Day ushers in new season

ELMIRA, N.Y. (WETM) – High School football is back and primed for the new season. Wednesday morning, teams from all over Section IV converged for a special media day opportunity at The Links at Hiawatha Landing golf course in Apalachin. The theme was simple, be better this year than the last for players, teams and […]

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Aug 12 • 7:29 PM EDT • Sports • sports.yahoo.com
Local Healthcare Organizations Partner to Bring Free Entertainment to the Darke County Fair

GREENVILLE - Several local healthcare organizations are joining together to present Partners in Care at the Fairgrounds, a collaborative initiative sponsoring

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Aug 12 • 4:05 PM EDT • Entertainment • mycountylink.com
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Elon Musk: SpaceX’s AI Revenue Will Surpass Its Entire Space Business “Next Month”

Elon Musk just told SpaceX employees that a business most people have never heard of will soon dwarf rockets, Starlink, and every other revenue line the company has ever built, and he gave a specific month.

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Aug 12 • 1:54 PM EDT • Business • finance.yahoo.com
Lazarus Exploits Windows Zero-Day to Gain SYSTEM Access and Deploy Backdoor

Lazarus-linked attacks exploit Windows CVE-2026-68820 as a zero-day to gain SYSTEM access and deploy Troy against defense and aerospace firms.

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Aug 12 • 1:39 PM EDT • Technology • thehackernews.com
VA Warns of National Postcard Scam as Health Care Notices Go Out to 3.8M Veterans

The department said fraudulent postcards had appeared in multiple states over the past year, claiming to be linked to the VA.

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Aug 12 • 10:58 AM EDT • Health • military.com
Wednesday Morning Links

Morning, all! Monday marked the first game in a stretch against a couple of cellar dwellers, and the Rangers capitalized by winning 4-1 in extras against the Angels. Unfortunately, the offense was flacid last night despite ample opportunities, so the signs aren’t pointing to a momentum building road trip. Cody Bradford was a bright spot, […]

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Aug 12 • 9:53 AM EDT • Sports • sports.yahoo.com
New fellowships link research, communities, youth purpose

The Purpose Science and Innovation Exchange has received a three-year, $3.5 million grant from the Bezos Family Foundation to launch two new fellowships aimed to help youth develop a sense of purpose.

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Aug 12 • 9:31 AM EDT • Science • news.cornell.edu
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Scientists turn Starlink into a giant scanner for Earth’s upper atmosphere

Researchers have found a clever new way to map a part of Earth’s upper atmosphere that is notoriously difficult to observe. Using orbital data from roughly 1,200 Starlink satellites, they reconstructed changes in atmospheric density about 500 kilometers above Earth. The approach could sharpen satellite tracking and help reduce the growing risk of collisions in increasingly crowded orbits.

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Aug 12 • 8:00 AM EDT • Science • sciencedaily.com
Valley Health Supports THRIVE Self-Sufficiency Program Through Community Partnership Grant

Valley Health’s Community Partnership Grant program supports local nonprofit organizations working to improve health and well-being across the communities we serve.

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Aug 12 • 8:00 AM EDT • Health • valleyhealthlink.com
NASA Swift Boost Spacecraft Prepares to Continue Mission

Katalyst Space uploaded a flight software update that reestablished attitude control of its LINK spacecraft, which is set to boost NASA’s Swift observatory.

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Aug 11 • 4:59 PM EDT • Science • science.nasa.gov
Boston Celtics Daily Links 8/11/26

All the Celtics news you need in one convenient place.

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Aug 11 • 3:21 PM EDT • Sports • sports.yahoo.com
Banking apps could help manage mental health, study finds

While the link between financial stability and mental health is well-established, a new University College Dublin (UCD) study reveals a major blind spot in current research: an overreliance on self-reported ...

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Aug 11 • 1:20 PM EDT • Health • phys.org
LG Launches Back to School Sale With Major Discounts on OLED TVs and Monitors

LG is hosting a big Back to School sale on its website this week, with deals on monitors, TVs, home appliances, and more. LG's discounts have been automatically applied and do not require any discount codes or special memberships. Note: MacRumors is an affiliate partner with LG. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.

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Aug 11 • 9:59 AM EDT • Technology • macrumors.com
Arizona Cardinals Daily Links:

Has Jacoby Brissett done enough to be the unquestioned starter in Week One for the Cardinals?

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Aug 11 • 9:51 AM EDT • Sports • sports.yahoo.com
Barcelona-linked Premier League defender chooses to join Atletico Madrid

Cristian Romero has made a decision on his future The Argentine centre-back had interest from several clubs, most notably Atletico Madrid, Barcelona, Inter Milan and Arsenal, but according to reports ...

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Aug 11 • 3:00 AM EDT • Sports • sports.yahoo.com
Guide to Austin politics: The Daily Texan explains city government, local leaders’ roles

The city of Austin is currently developing their annual city budget and considering a bond issue, while several charter amendments (link once story is up) are up for a vote in November. With all this activity in City Hall, the Texan is providing a guide to new UT students on how Austin politics works and...

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Aug 10 • 11:52 PM EDT • Politics • thedailytexan.com
Psychopathic Tendencies Are Linked to Microbes Inside Your Body, Study Reveals

It’s not just you.

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Aug 10 • 11:49 PM EDT • Science • sciencealert.com
Klay Thompson sends Lakers-related message on Instagram

Klay Thompson added some fuel to the rumors linking him to the Lakers with a post on his Instagram account.

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Aug 10 • 11:12 PM EDT • Sports • sports.yahoo.com
The science behind tomatoes and better health

Tomatoes contain lycopene and other nutrients linked to heart and prostate health. Learn the science and how to add tomatoes to your diet.

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Aug 10 • 4:07 PM EDT • Science • utphysicians.com
The science behind tomatoes and better health

Tomatoes contain lycopene and other nutrients linked to heart and prostate health. Learn the science and how to add tomatoes to your diet.

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Aug 10 • 4:07 PM EDT • Health • utphysicians.com
Boston Celtics Daily Links 8/10/26

All the Celtics news you need in one convenient place.

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Aug 10 • 3:17 PM EDT • Sports • sports.yahoo.com
Study links student gambling problems to mental health

As gambling becomes more accessible to college students, a statewide study of Mississippi's public universities found gambling problems frequently occur alongside depression, anxiety and substance use.

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Aug 10 • 1:20 PM EDT • Health • medicalxpress.com
Ex-Eagles Super Bowl Champion Linked to NFC North Team

A former Philadelphia Eagles Super Bowl champion is still waiting for his phone to ring about a job from an NFL team.Offensive guard Mekhi Becton did not have a good season after winning it all with the Eagles. Becton had a failed one-year run with the Los Angeles Chargers, resulting in his release and now […] The post Ex-Eagles Super Bowl Champion Linked to NFC North Team appeared first on HEAVY.

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Aug 10 • 12:42 PM EDT • Sports • sports.yahoo.com
Rangers linked to former 2nd overall pick in NHL Draft

The Rangers need to make this move happen.

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Aug 10 • 9:35 AM EDT • Sports • sports.yahoo.com
Johnson turns Democrats’ socialist civil war into new weapon for midterms

House Republicans launch "Contrast for America" website targeting DSA-linked Democrats, echoing the 1994 "Contract with America" midterm strategy.

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Aug 10 • 9:28 AM EDT • Politics • foxnews.com
Science backs calls for limiting screens in schools

School device use links with lower test scores and distractions abound. But reversing the entrenched pandemic pivot to screens will be hard.

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Aug 10 • 9:00 AM EDT • Science • sciencenews.org
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice

AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.

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Aug 10 • 8:24 AM EDT • Health • fiercebiotech.com
Study links better midlife vascular health to nearly 13 more dementia-free years

A long-term study of 12,409 adults found that a greater burden of diabetes, hypertension, and current smoking in midlife was associated with substantially fewer years lived free of dementia. Adults with none of these risk factors had about 30.1 dementia-free years from age 55, compared with 17.5 years among those with all three, a difference of nearly 13 years.

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Aug 10 • 1:49 AM EDT • Health • news-medical.net
Long COVID Linked to Lasting Damage in The Brain's Dopamine System

The virus can cause serious damage.

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Aug 9 • 9:23 PM EDT • Science • sciencealert.com
Health expert sounds alarm over rising outbreaks

NYU Langone gastroenterologist Dr. David Bernstein analyzes the Cyclospora and Salmonella outbreaks linked to contaminated produce. He details key symptoms, infection sources and essential food safety tips.

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Aug 9 • 2:36 PM EDT • Health • foxnews.com
Israel rejects Trump's Gaza plan, more details emerge on the Strait of Hormuz

Tehran suggests that vessels linked to “hostile countries” will be barred from the waterway.

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Aug 9 • 2:30 PM EDT • Politics • spectrumlocalnews.com
The Watch: Microplastics Linked To Fatty Liver Disease

Plastic used in food packaging is most common type found in liver…workers exposed to pesticides at higher risk for Lou Gehrig’s disease…last year’s measles outbreak cost $5.4 million to contain…and more

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Aug 9 • 1:17 PM EDT • Health • publichealthwatch.org
N.Y. state AG warns of 'gold bar scams'

The scams involve a fake cybersecurity message on victims' computers, claiming their financial accounts have been compromised or linked to some sort of crime.

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Aug 9 • 11:11 AM EDT • Politics • spectrumlocalnews.com
Video Health alert for meat and poultry potentially linked to a salmonella outbreak

Federal officials have issued new public health warnings on meat products with recently recalled jalapenos, potentially linked to salmonella in more than two dozen states.

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Aug 9 • 8:00 AM EDT • Health • abcnews.com
Japan football association investigates four referees over KFA sexual entertainment allegations

The JFA is investigating four Japanese referees linked to matches cited in allegations that the KFA provided sexual entertainment to foreign officials in 2011 and 2012.

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Aug 9 • 4:38 AM EDT • Entertainment • koreajoongangdaily.com
Wine, beer, or spirits? Massive study finds a surprising health divide

A study tracking more than 340,000 adults for over a decade found that heavy drinking increased the risk of death regardless of beverage type. At lower levels, however, the picture became more surprising: beer, cider, and spirits were linked to higher mortality, while wine was associated with lower risk. Moderate wine drinkers had a 21% lower risk of cardiovascular death compared with people who rarely or never drank.

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Aug 8 • 8:00 PM EDT • Health • sciencedaily.com
4 ways to show your cat you love them, according to science

Experts say slow blinking, respecting boundaries, proper petting, and interactive play help build trust and strengthen your bond with your cat.

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Aug 8 • 11:41 AM EDT • Science • creators.yahoo.com
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Cutting sweet foods doesn’t curb cravings or improve health

Changing how much sweet-tasting food people eat may not change how much they crave or enjoy sweetness after all. In a six-month trial, researchers found that people assigned to high-, low-, or average-sweetness diets showed no meaningful differences in their preference for sweet foods, body weight, or markers linked to diabetes and heart disease. Many participants also drifted back toward their previous eating habits once the trial ended.

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Aug 8 • 8:00 AM EDT • Science • sciencedaily.com
Cutting sweet foods doesn’t curb cravings or improve health

Changing how much sweet-tasting food people eat may not change how much they crave or enjoy sweetness after all. In a six-month trial, researchers found that people assigned to high-, low-, or average-sweetness diets showed no meaningful differences in their preference for sweet foods, body weight, or markers linked to diabetes and heart disease. Many participants also drifted back toward their previous eating habits once the trial ended.

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Aug 8 • 8:00 AM EDT • Health • sciencedaily.com
Is watching too much TV bad for your brain? Possibly

Watching a lot of television was linked to smaller brain volume in areas important for language and thinking, new study finds. Here’s what that means.

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Aug 8 • 6:30 AM EDT • Health • cnn.com
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‘I couldn’t breathe’: the deadly health burden of wildfire smoke

Scientists race to untangle complex links between exposure and mortality as fire weather grows more prevalent

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Aug 8 • 1:00 AM EDT • Health • theguardian.com
Patriot Games to feature America's young sports stars

High school sports are an enduring part of the landscape in communities across America, linking people in a common experience.

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Aug 7 • 4:56 PM EDT • Sports • share.america.gov
Jalapeños linked to a U.S. salmonella outbreak are tracked to a Mexican farm and a distributor

Jalapeño peppers linked to a multistate salmonella outbreak have been traced back to a grower in Sinaloa, Mexico, federal officials say.

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Aug 7 • 11:17 AM EDT • Health • pbs.org
In 1934, scientists heard reports of mushrooms causing visions of tiny people; in 2026, DNA linked the phenomenon to one species in China and the Philippines

In 1934, Western scientists first heard reports from Papua New Guinea of wild mushrooms causing visions of tiny people, a phenomenon called "mushroom madness." Nearly a century later, DNA sequencing has confirmed that a single, identical mushroom species causes these same hallucinations in communities thousands of miles apart in China and the Philippines.

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Aug 7 • 10:52 AM EDT • Science • timesofindia.indiatimes.com
Avoiding These 3 Things in Midlife Is Linked to 13 More Dementia-Free Years

There are still opportunities in midlife to prevent dementia or delay its onset, a new study finds.

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Aug 7 • 8:51 AM EDT • Health • time.com
Klay Thompson’s Dad Sends 2-Word Message on Lakers Rumors

Klay Thompson is continuing to be linked to the Los Angeles Lakers, and his father, Mychal Thompson, made his stance on the rumors very clear. The post Klay Thompson’s Dad Sends 2-Word Message on Lakers Rumors appeared first on HEAVY.

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Aug 6 • 10:05 PM EDT • Sports • sports.yahoo.com
Wearable fingertip sensor identifies physical patterns linked to stress and anxiety

Researchers have shown that measurements taken from a person's fingertip could help identify physical patterns associated with stress, anxiety and depression. The international study, involving experts ...

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Aug 6 • 6:00 PM EDT • Health • medicalxpress.com
Comcast Business is Deploying Private Wireless Network in Smartlink Headquarters

The network will combine cellular and radio services to enhance wireless coverage in office buildings.

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Aug 6 • 3:41 PM EDT • Business • broadbandbreakfast.com
Scientists identify mushroom behind ‘tiny people’ hallucinations

DNA sequencing links independent reports of ‘Lilliputian’ hallucinations to a single mushroom species—one with no previously identified psychoactive compounds, suggesting the presence of a new...

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Aug 6 • 1:03 PM EDT • Science • attheu.utah.edu
Which type of thinker are you? + US explosive diarrhoea outbreak

Madeleine Finlay is joined by Ian Sample, Guardian science editor, to discuss three eye-catching science stories including an investigation that has identified four distinct types of thinker. Also on the agenda is the unprecedented cyclosporiasis outbreak in the US which has now been linked to two fatalities, and the funding cuts that threaten the iconic Jodrell Bank world heritage site, home to the Lovell telescope

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Aug 6 • 9:53 AM EDT • Science • theguardian.com
Why truckers always seem to be on the phone while they drive

Social media is linked to feelings of isolation, but less so for truckers. They benefit from long phone calls and connections on apps like FaceTime and WhatsApp.

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Aug 6 • 9:00 AM EDT • Health • calmatters.org
More than 280,000 eggs delivered to Foodlink as part of price fixing settlement

The AG's office says three companies coordinated to artificially inflate prices.

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Aug 6 • 8:11 AM EDT • Business • spectrumlocalnews.com
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Butterfly lilies wing their way to Science

Many animals and plants show left-right differences in how their bodies or organs are arranged, but we still know little about how such asymmetries evolve or how genes control them in natural populations. Mirror-image flowers, in which female and male sex organs are deflected to opposite sides in left- and right-handed forms, provide a notable example of such asymmetry. Here, we studied South African butterfly lilies, where individual plants produce only left- or right-handed flowers. Their mirror-image flowers promote outcrossing by depositing pollen from each floral form onto a specific region of a pollinator’s body that matches the stigma position of the opposite form. This suggests that selection for efficient pollen transfer between forms maintains this natural polymorphism. Our work uncovers a hemizygous supergene that coordinates the left-right orientation of female and male sex organs in mirror-image flowers by linking two independently acting genes for style and stamen handedness in a single, nonrecombining genomic segment. This architecture ensures the coinheritance of a matched pair of organ orientations that is essential for efficient cross-pollination between floral forms. At the developmental level, we show that floral handedness emerges from the interaction between an intrinsic tissue chirality and a gravitropic response that orients the style and median stamen relative to gravity. Together, these findings reveal how a supergene, hormone and microRNA signaling, tissue chirality, and an external physical cue combine to produce and maintain a stable left-right polymorphism in natural plant populations.

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Aug 6 • 8:00 AM EDT • Science • eurekalert.org
Wellcome Photography Prize Links Science to the Human Experience

The global photography competition recognizes creative storytelling that showcases how science and health affect people’s lives.

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Aug 6 • 12:00 AM EDT • Science • the-scientist.com
Weekly Entertainment Report: Live music and lively arts, Aug. 6-9

"One good thing about music, when it hits you, you feel no pain." — Bob Marley

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Aug 5 • 10:52 PM EDT • Entertainment • manchester.inklink.news
Nearly half of dementia cases may be linked to risks you can change

A long-term brain study found that common risks such as smoking, high blood pressure, heart disease, and high blood lipids were strongly linked to damage associated with vascular dementia. The findings suggest that healthier lifestyle choices could help delay dementia by reducing several harmful brain changes at once.

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Aug 5 • 8:00 PM EDT • Science • sciencedaily.com
World’s most-used weedkiller disrupts honeybee brains

Glyphosate was long thought to be safe for honeybees because they lack the enzyme the chemical targets in weeds. However, researchers found that exposed bees foraged 13 percent less after only three days and showed changes in brain chemicals linked to behavior. Across a whole hive, that decline could reduce honey production, weaken pollination, and threaten long-term survival.

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Aug 5 • 8:00 PM EDT • Science • sciencedaily.com
Halo Studios is the latest Xbox Games Studio to be hit by layoffs just days after Campaign Evolved launch, as reports reveal "troubled" development

A number of developers previously employed at Halo Studios have posted on LinkedIn confirming layoffs at the studio.

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Aug 5 • 6:49 PM EDT • Technology • windowscentral.com
New Glenn explosion linked to rocket engine valve

Blue Origin has traced the explosion of its New Glenn rocket during a static-fire test in May to a valve in the rocket’s BE-4 engine.

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Aug 5 • 6:30 PM EDT • Technology • spacenews.com
Trump files emergency motion to block BBC from getting financial details about business empire

President Trump’s attorney filed a Wednesday emergency motion seeking to block the BBC from obtaining financial records linked to his trust. The British broadcaster received approval from a judge …

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Aug 5 • 4:57 PM EDT • Business • thehill.com
Cyclosporiasis Map 2026, Foods to Avoid as Outbreak Spreads to 47 States

A massive outbreak of the “explosive diarrhea parasite” cyclospora has been linked to shredded lettuce. Where are cases rising, and what are the other possible sources?

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Aug 5 • 4:39 PM EDT • Health • today.com
Cyclosporiasis cases in Michigan climb to over 12,000, state health officials say

Michigan health officials reported 12,218 cases linked to an outbreak of cyclosporiasis on Wednesday, an increase of 710 cases since ​its last update a day earlier.

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Aug 5 • 11:23 AM EDT • Health • reuters.com
Cyclosporiasis Cases in Michigan Climb to Over 12,000, State Health Officials Say

Aug 5 (Reuters) - Michigan health officials reported ⁠12,218 ⁠cases linked to an outbreak ⁠of cyclosporiasis on Wednesday, an increase of 710 cases since its last update a day earlier. Michigan has reported the first two ‌deaths associated with the outbreak, ‌saying both individuals had significant ...

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Aug 5 • 11:22 AM EDT • Health • usnews.com
Gotham FC, Flamingo and the Women's Sports Foundation® Announce Built to Move, A New Study Linking Movement to Greater Body Appreciation

JERSEY CITY, N.J. (Aug. 5, 2026) – Gotham FC, Flamingo and the Women’s Sports Foundation (WSF®) announced Wednesday the findings of new research exploring the relationship between physical activity an

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Aug 5 • 10:01 AM EDT • Sports • gothamfc.com