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Health systems must shift AI use from automation to transformation
While healthcare investments in AI are two to three times that of other industries, most providers focus AI's power on tackling administrative tasks. But AI's true value is in transforming care, explain experts at the HIMSS AI in Healthcare Forum.
Gilbert-backed Cosm gets $100M Sony investment as immersive theater operator expands to Detroit
A Cosm location in downtown Detroit is expected to open in September as part of Dan Gilbert’s Bedrock LLC real estate firm’s Development at Cadillac Square project.
US economy grew at 2.1% in first quarter
First-quarter GDP grew at 2.1%, above the expected 1.6%, as equipment investment in AI and computers along with consumer spending led growth.
Ebola response highlights value of African science
With African scientists leading the way in the latest Ebola response, Catherine Kyobutungi makes the case for long-term investment.
This beverage stock is likely to rise ahead of coffee business spinoff, Barclays says
The investment bank upgraded shares to overweight from equal weight.
Prosus Investment Values Health Insurer Alan at $6.3 Billion
Prosus—the largest shareholder in Tencent Holdings and owner of food-delivery company Just Eat Takeaway—is investing €400 million in Alan.
Ryman Hospitality Properties, Inc. Addresses Recent Media Reports Regarding Opry Entertainment Group
NASHVILLE, Tenn., June 24, 2026 (GLOBE NEWSWIRE) -- Ryman Hospitality Properties, Inc. (NYSE: RHP) (the “Company”), a leading lodging and hospitality real estate investment trust that specializes in group-oriented, upscale convention center resorts and entertainment experiences, today addressed recent media reports regarding the Company’s Opry Entertainment Group (“OEG”) business. Colin Reed, Executive Chairman of Ryman Hospitality Properties said, “We are incredibly proud of our OEG business an
Alex Rodriguez on how to build a business empire and what an MLB strike would mean to baseball
Baseball star Alex Rodriguez started building his business with a single $250,000 investment in 1995.
FMOL Health’s E.J. Kuiper touts $500M in capital spending, strong financials
FMOL Health has committed more than $500 million to capital investments since E.J. Kuiper took over as president and CEO.
Sony Pictures Entertainment Invests $100M In Cosm, Operator Of "Shared Reality" Venues
Sony Pictures Entertainment has made a $100 million strategic investment in Cosm, a venture-backed operator of "shared reality" venues.
Governor Morrisey Announces $2.4 Million Investment to Expand Worksite Clinics Across West Virginia
CHARLESTON, W.Va. - Governor Patrick Morrisey today announced a $2.4 million investment to expand access to worksite-based healthcare services across West Virginia. Through the state's Rural Health Transformation Program (RHTP), the funding will expand employer-based health services and strengthen workforce participation as part of the Health to Prosperity (HTP) initiative. With this announcement, total funding opportunities and implementation initiatives under RHTP now exceed $88.5 million.
Financing the Future: Leaders Make the Investment Case for Women's, Children's and Adolescents' Health
With development assistance declining and health systems under growing strain, leaders at Africa Health ExCon called for a shift from fragmented financing to integrated, sustainable investment in women’s, children’s and adolescents’ health. Discussions highlighted domestic financing, private sector engagement, service integration and climate-resilient health systems as pathways to greater impact.
Keeping The Front Door of Healthcare Open: Our Investment in Assort Health
We’re thrilled to announce that Menlo Ventures is leading the Series C in Assort Health—the AI platform transforming the front door of healthcare.
Highland Park business faces eviction after private equity buys their building
A Highland Park small business owner faces eviction after a real estate investment company bought her building last month.
Private equity’s move into youth sports brings some truths home
Investments create benefits but also lead to higher costs and risk of inequality
MARIANNETTE MILLER-MEEKS: Iowa First — A Historic Investment in Rural Health Care
Read Congresswoman Miller-Meeks' Latest Op-ed Published in the Indianola Advocate!
Microsoft Needs Its Own AI Strategy | AI & Business for June 23
Plus, tech job cuts, Sam Altman’s web of investments and Asia’s stock-market fever.
Buy IBM as investors underappreciate the strength of its software business, says JPMorgan
The investment bank upgraded the legacy tech name to overweight from neutral.
Brexit Has Cost the UK Growth, Analysts Say, in the Decade Since the Vote
Citing lower trade and investment, analysts broadly agree that Britain’s economy is smaller than it would have been if the country had stayed in the E.U.
Business travel buyers look to AI for help managing disruption
Separate surveys from Business Travel Show Europe and TravelTech Show highlight growing investment in artificial intelligence as travel companies look to manage disruption, improve traveler experiences and reduce costs.
Pennsylvania Gov. Josh Shapiro on new fast track business development and company investments
Gov. Josh Shapiro (D-Pa.) joins 'The Exchange' to discuss business development in the state, taxes in the state and more.
PWHL adds Kilmer Sports Ventures, Ilitch Companies as first outside investors
Just one month after completing its third season, the Professional Women’s Hockey League has added its first outside investment, the league announced on Monday morning. Kilmer Sports Ventures, which is led by Toronto businessman Larry Tanenbaum, and Ilitch Companies, the parent company of the NHL’s Detroit Red Wings and MLB’s Tigers, have joined the league as partners. Since its inception, the league has operated under a single-entity ownership model, meaning Mark Walter — the billionaire owner
EasyJet rejects £4.7bn takeover offer from US investment firm Castlelake
The airline describes the latest bid approach from Castlelake as "highly opportunistic".
Why Great Businesses Can Be Terrible Investments
Why great businesses can be terrible investments when high valuations, crowded ownership and unrealistic expectations overwhelm strong company performance.
Ex-Nvidia leaders launch EverGreen to back AI startups
EverGreen, founded by ex-Nvidia execs like Greg Estes, supports AI startups through investment and mentorship, leveraging Nvidia alumni networks.
Bigger, fewer, tougher: the new era of China-US biotech partnerships
China’s biotech boom continues to attract Western drug makers even as Washington expands investment and technology controls.
Jim Cramer Says Clover Health Was a Good Speculative Pick But Still Prefers UnitedHealth and CVS
Clover Health Investments, Corp. (NASDAQ:CLOV) was among the stocks on Jim Cramer’s radar on Mad Money, as he advised investors to care about where a stock is going, not where it has been. A caller referenced Cramer’s previous comment, calling it speculative, and noted that the company reported GAAP profitability in Q1 2026 and guided […]
World Refugee Day 2026
Marking World Refugee Day 2026 and 75 years of the Refugee Convention, WHO calls for inclusive and resilient health systems that ensure refugees access to quality, continuous and culturally sensitive care. With 117.8 million people forcibly displaced worldwide, the organization emphasizes that protecting refugee health strengthens public health, preparedness and social cohesion. WHO highlights progress in integrating refugees into national health policies while urging greater investment, stronger data systems, emergency preparedness and meaningful participation of refugees in health planning and governance.
The UMN, M Physicians and Fairview Health Services reach finalized healthcare agreement
On June 12, the University of Minnesota’s Board of Regents voted unanimously in collaboration with other governing bodies to approve a new 10-year agreement between the University, M Physicians and Fairview Health Services, a partnership that will continue to support healthcare services and investments across the state. With the current agreement scheduled to expire at...
SailGP’s New Zealand team sells majority stake to private equity firm MSP Sports Capital
New Zealand are the last of the 13 SailGP teams to secure private investment.
Amazon drops Sam Altman movie months after OpenAI investment
Luca Guadagnino's "Artificial," a movie about Sam Altman, has been dropped by Amazon MGM Studios. Earlier this year, OpenAI and Amazon deepened ties.
O'Shaughnessy Ventures Backs Writer Telling the Human Story of Science
/PRNewswire/ -- O'Shaughnessy Ventures LLC (OSV), an investment firm that empowers creators, has awarded an O'Shaughnessy Fellowship to Jolie Gan, a writer...
Why Buying Health AI Is Just the Beginning
Health leaders haven’t figured out how best to integrate AI products into their workflow, nor how to demonstrate the financial return on their investment, panelists said at a U.S. News Healthcare of Tomorrow conference in Washington Thursday. Health systems are struggling to “take something like ...
RWJBarnabas Health Invests $1.5 Million to Support Local Community Health Initiatives in New Brunswick, Middlesex County
RWJBarnabas Health today announced a combined $1.5 million investment to support local organizations working to address barriers to care, food insecurity and economic stability among underserved communities in New Brunswick and Middlesex County.
AI and Telemedicine Can Fill Healthcare Gaps, Execs Say – But Only If Washington Helps
Major health system leaders say investments in virtual care, ambient AI medical scribes, automated referrals and other new tech tools could ease a critical workforce shortage that struggles to keep up with widespread chronic disease and medical deserts. But they still need regulators to revamp ...
Paulson Wins $47 Million in Arbitration With Ex-Business Partner
John Paulson was awarded more than $47 million by an arbitrator who found that the billionaire’s former Puerto Rico business partner cheated him on one investment and usurped him on another.
Elanco to launch $25M VC program focused on animal health innovation
The fund will target investments in animal-health therapeutics and technologies designed to improve care, Elanco said.
NM spent nearly $844M on behavioral health, but 'investment is not yet matching the outcome'
New Mexico has spent $843.5 million since 2022 to rebuild state’s behavioral health system but still faces problems.
Drone owners share what’s next for spray businesses
Those who use spray drone technology are in the midst of a technological advancement. But what do they see coming, and what’s their next investment?
Health leaders urged to curb aggressive AI spending
This HIMSS26 APAC speaker advises leaders to pace their AI investments despite the technology's rapid development.
Businesses, commuters adjust for two-year Fort Bragg gate closure
The repairs to the All-American Freeway and the replacement of the Gruber Road Bridge are necessary investments, a Fort Bragg spokesperson said.
RWJBarnabas Health Invests $1.7 Million to Support Local Community Health Initiatives in Jersey City, Hudson County
RWJBarnabas Health today announced a combined $1.7 million investment to support local organizations working to address barriers to care, food insecurity, and economic stability among underserved communities in Jersey City and Hudson County.
US business inventories increase as expected in April
U.S. business inventories increased strongly in April, suggesting that inventory investment could contribute to economic growth in the second quarter.
Health services deal value holds steady in 2026 with higher bar for investment: PwC
The number of health services deals dipped in the first half of 2026 but deal value "remained resilient" as strategic acquirers and dealmakers "reprice risk," according to a midyear outlook report | The number of health services deals dipped in the first half of 2026 but deal value "remained resilient" as strategic acquirers and dealmakers "reprice risk," according to a midyear outlook report from PwC.
Spain-Cape Verde draw doesn’t alter Atlanta’s business recruitment goal
Atlanta leaders and their business counterparts in Spain have their eye on a different ball, a long-term goal of leveraging the World Cup to increase trade and investment.
Keeping Rhode Islanders covered requires a smart investment in our health and economy
Our state must expand and make permanent state-funded subsidies while finding strategies to keep Rhode Islanders insured, writes Neighborhood Health Plan of Rhode Island president.
Mood darkens among German auto suppliers as investment, hiring fall, survey shows
German automotive suppliers expecting business conditions to worsen over the next year now outnumber the industry's optimists, a survey showed on Wednesday, as domestic hiring sinks to a new low and investment in the sector moves overseas.
Montana Board of Investments closes deal on Laurel land for proposed forensic mental health facility
The state has closed on its purchase of 114 acres in west Laurel proposed for a forensic mental health facility and is now asking Yellowstone County to rezone the property.
Seattle business group says JumpStart tax is pushing jobs, investment toward Bellevue
Seattle’s payroll tax was created nearly six years ago with a promise to tax the city’s highest-paid workers and use the money to help with economic recovery
UNC Health plans to take over Goldsboro hospital with $675 million investment
Officials said the money would go toward expanding healthcare services, upgrading facilities and technology, and recruiting more doctors at the Goldsboro hospital.
Researchers receive funding to launch USC’s first clinical study of psilocybin for mental health
Related News NIH investment totaling 30.7M will expand USC-led AI effort to decode Alzheimer’s disease April 2, 2026 USC study maps brain network changes linked to bipolar disorder severity and […]
What does the appointment of H.E. Monica Geingos as PMNCH Board Chair mean for Namibia, Africa and the future of global health leadership?
The appointment of H.E. Monica Geingos as PMNCH Board Chair marks a significant moment for global health leadership. As funding pressures and health inequities grow, her leadership reflects the increasing role of African voices in shaping global health governance and advancing equity, accountability and investment for women’s, children’s and adolescents’ health and well-being.
Apptio Unveils Conversational Insights and New Suite of AI-Powered Capabilities to Translate Complex Technology Spend into Measurable Business Outcomes
Apptio announced significant updates to its solution suite designed to turn technology investment into measurable business outcomes and establish best practices for the financial governance for AI in a time of record infrastructure investments.
Trump insists U.S. will not invest money in Iran as part of peace deal
Others in the president's circles, including Vice President JD Vance, have suggested Tehran could gain access to a major investment fund if it upholds its side of the peace accord.
To be America's Top State for Business in 2026, 'speed to market' wins
CNBC’s 2026 America’s Top States for Business rankings is a race as companies chase record investments in AI and defense in deciding where to locate.
United States Announces U.S. Government Members of the U.S.-Uzbekistan Business and Investment Council
United States Announces U.S. Government Members of the U.S.-Uzbekistan Business and Investment Council Press Release June 16, 2026 Today, at the fifth annual Tashkent International Investment Forum (TIIF 2026), the United States announced the following inaugural members of the U.S.-Uzbekistan Business and Investment Council: U.S. International Development Finance Corporation (DFC) Vice President Bethany Aquilina Brez Export-Import Bank of the United States (EXIM) Senior Vice President Sarah Witten Assistant Secretary of Commerce, David Fogel Assistant Secretary of State for Economic, Energy, and Business Affairs, Caleb Orr U.S. Ambassador to Uzbekistan, Jonathan Henick Launched in Washington, D.C., in April 2026, the U.S.-Uzbekistan Business and Investment Council serves as the premier bilateral platform to accelerate trade and catalyze private sector investment between the United States and Uzbekistan. The Council is Co-Chaired by Special Envoy for South and Central Asia, Ambassador Sergio Gor and Saida Mirziyoyeva, Head of the Administration of the President of the Republic of Uzbekistan. The Council gives American businesses direct access to U.S. government financing, trade promotion, and market development tools to execute large-scale projects in Uzbekistan. Uzbekistan holds significant reserves of critical minerals essential to U.S. technology, defense, and energy sectors. The Council provides a direct mechanism to advance U.S. access to these resources through transparent, mutually beneficial partnerships. Through their participation, the American members of the Council will deepen the institutional framework for American commercial engagement in Uzbekistan.
Informa Markets and Thailand's Health Ministry Join Forces To Deliver a Successful Edition of International Healthcare Week 2026 in Bangkok
Informa Markets joins forces with Thailand's Department of Health Service Support (DHSS) to unveil International Healthcare Week 2026, a transformative regional healthcare platform that will elevate Thailand's position as a world-leading medical and wellness hub and catalyze new waves of investment, innovation, and international partnerships across the healthcare industry.
Baker leaders, BREC propose multimillion-dollar investment in youth sports facilities
City leaders and BREC officials are moving forward with plans to invest millions of dollars into youth sports facilities in Baker.
Edward Jones Expands Workplace Retirement Solutions for Business Owners and Their Employees
With new products, investments and product partners, Edward Jones is helping business owners support employees while preparing for their own financial futures....
Here’s Why Baron Real Estate Fund is Constructive on Caesars Entertainment (CZR)
Baron Capital, an investment management company, released its Q4 2025 letter for its “Baron Real Estate Fund”. A copy of the letter is available to download here. Baron Real Estate Fund was recognized as the Best Real Estate Fund Over Three Years at the 2026 LSEG Lipper Funds Awards, reflecting the three-year performance ending December 31, […]
PENN Entertainment opens $100m hotel at Hollywood Casino Columbus
PENN Entertainment has officially opened a new hotel tower at its Hollywood Casino Columbus site in Ohio, following a $100m investment.
Themed Entertainment Giant Teases $55 Billion Investment
One of the world’s leading themed entertainment developers has teased a $54.4 billion project which is expected to be one of the biggest investments in its history.
City of Buffalo to receive $70M in state aid
A $24 million investment is also going towards the hunger relief organization FeedMore WNY.
UK and Japan agree £18bn investment deal
Japanese firms will spend billions on UK infrastructure and offshore wind, Downing Street says.
Why Accel Entertainment (ACEL) Is Up 9.5% After Beating Revenue Forecasts With 8.5% Growth
Earlier this quarter, Accel Entertainment reported quarterly revenue growth of 8.5% year on year, surpassing analyst expectations even as operating income trends were mixed. This revenue surprise stands out because it reflects resilience in Accel’s local gaming footprint while many consumer discretionary peers also beat sales forecasts. Next, we’ll examine how this stronger-than-expected revenue performance may influence Accel Entertainment’s existing investment narrative and growth...
Bob on Business: A whole city devoted to pickleball? Developer serves up Pickle City Fort Worth
Also, former Heim property sold; small business closures; and local firm plans AI investment.
Garbe to partner with Boston's Berkeley Investments
Garbe, a German real estate investor and developer, is partnering with Boston-based Berkeley Investments for its entrance into the US market.
Sharon O'Keefe
As president of the University of Chicago Medical Center and chief operating officer of the 1,286-bed University of Chicago Medicine health system, Sharon O’Keefe oversees a clinical enterprise with annual operating revenue of $2.21 billion. In the past 18 months, UChicago Medicine opened an expanded adult emergency department—a $39 million investment—and an adult trauma center. Since 2011, the system has generated annual growth of nearly 5 percent in revenue and 4 percent in patient admissions. O’Keefe previously was president of Loyola University Medical Center and executive vice president and chief operating officer at Boston’s Beth Israel Deaconess Medical Center. She serves on the Illinois Hospital Association finance and audit committee and is on the American Heart Association’s Midwest affiliate board.
Public Health at an Inflection Point: Aligning State Systems to Strengthen Population Health
The US public health system is facing an inflection point characterized by chronic underinvestment, workforce and service delivery challenges, outdated data infrastructure, growing health inequities, and increasing instability within the broader health care safety net including projected Medicaid coverage changes and continued rural hospital closures.
Bipartisan Policy Center to Host Webinar on Rural Health Transformation Program
The Bipartisan Policy Center will host a webinar June 30 from 11 a.m. to noon EDT on how states are leveraging funding through the Rural Health Transformation Program (RHTP) to strengthen rural healthcare delivery through technology and workforce investments.
Overview of WHO Member State Interventions at WHA79 on Women’s, Children’s and Adolescents’ Health (WCAH)
WHA79 highlighted a critical turning point for women’s, children’s and adolescents’ health (WCAH) amid record declines in development assistance, growing humanitarian crises and ongoing reforms of the global health architecture. PMNCH advocated for WCAH to remain central to health system reform, emergency response and financing discussions, emphasizing that sustainable investments, country-led governance and protection of essential services are vital to prevent reversals in hard-won health gains and accelerate progress toward the SDGs.
Tulane report urges healthcare investment to improve Louisiana economy, reverse population loss
A new report argues that Louisiana’s future population and economic growth depends on increasing investments in healthcare services and passing policies that address health disparities.
Could a Moneyball-inspired business fund help WNC recover from Helene?
Hoping to find undervalued small businesses, Optimist Ventures is aiming to grow Helene-impacted businesses through public and private investment.
Dehko Enterprises Announces Expansion of Business Development and Strategic Investment Operations
Michigan-Based Company Expands Growth Initiatives Across Business Development, Strategic Investments, Brand Building, and Emerging OpportunitiesWest Bloomfield, Michigan--(Newsfile Corp. - June 12, 2026) - Dehko Enterprises today announced the expansion of its business development and strategic investment operations as part of a long-term initiative designed to strengthen the company's position across multiple industries while pursuing new opportunities in business growth, strategic...
First lady introduces Trump Accounts for foster youth
The U.S. Treasury is allowing states' child welfare agencies to set up the investment accounts
WATCH: First lady Melania Trump announces new investment accounts for foster youth
First lady Melania Trump and Treasury Secretary Scott Bessent on Thursday announced the launch of Fostering the Future Accounts, a spinoff of the Trump Accounts investment funds meant to give $1,000 to every newborn whose parent opens one.
Wellston Industrial Park to Transition to Manufacturing, Logistics Business Park
City of Wellston, County LCRA working with THO Investments on project Working together, the Land Clearance for Redevelopment Authority of the County of St. Louis (LCRA), managed by St. Louis…
New M5 junction would be 'helpful'
A Worcestershire business leader says a new M5 junction could be "really helpful" for investment.
Blount County business development focuses on small businesses, community growth
Tennessee being a business-friendly state has led to investment from Memphis to Chattanooga, Knoxville and the Tri-Cities.
Johns Hopkins announces major new investment in cutting-edge life sciences research
The Life Sciences Research Initiative will direct $80 million annually over the next two years to fuel breakthroughs and discoveries to improve human health
Crown family’s Richard C. Goodman sells Oak Street condo
Goodman, who has been a managing partner of the Crown family’s investment firm, bought the condominium in 2013.
College of Business grad’s investment prowess leads to prestigious summer program at Harvard
Most undergraduate students do not manage $6.2 million in assets, but Dola Popoola is not most students. While completing her double major in finance and marketing, the Oregon State University Presidential Scholar and soon-to-be College of Business graduate also served as president of the Oregon State Investment Group, one of the top 25 student-managed investment funds in the nation. That experience helped cement her love of finance and taught her what it takes to be successful in the industry, she said.
Canes' success spilling over to Raleigh business sector
"We've seen significant investment across numerous industry sectors and job growth here in this region."
City Files Suit Regarding Proposed Business
The City of Greenville has filed a lawsuit in Bond County Circuit Court against the company and three individuals who proposed a sports bar/restaurant business in the former Watson’s Drug Store building on the Greenville square. Named as defendants are W.G.O. Investments, LLC, and member managers of the developer, Joseph Gira, Tim O’Donnell and Dan
Bay Area Host Committee Celebrates Opening of Sports for All Hub at LIFE Academy and United for Success Academy in Oakland
New fully renovated field brings transformative investment to Fruitvale neighborhood, continuing BAHC's commitment to equitable sports access across the Bay Area Oakland, CA – June 9, 2026 – The Bay Area Host Committee (BAHC) celebrated today the official opening of its Sport
Seattle slips in ranking of best U.S. cities for foreign investment, fueling concerns about business climate
The fourth annual list compiled by British newspaper Financial Times and stock market index Nikkei ranks Seattle 13th among 95 U.S. cities — a drop of 11 places from last year's second-place position.
Meta launches $115M skilled trades academy with guaranteed jobs for graduates in 4 states
Meta launches America's Workforce Academy with $115 million investment, offering free skilled trades training with guaranteed jobs for all graduates.
We can create the future of science right now
Paul Litvak is the founder and Executive Director of the Robyn Dawes Institute and a Visiting Scholar at UC Berkeley. He has a PhD in Behavioral Decision Research from Carnegie Mellon where he studied emotions and the sunk cost bias. Over 15 years in industry, he solved a wide range of challenging technical problems. At Meta he created models optimizing the ad review process. At Google he ran experiments to measure social influence. At Airbnb, he was a product manager leading machine learning teams optimizing search ranking and price suggestions. He also co-founded and led product at Rhythmic Health, a venture-backed biosensing startup, creating an accurate low cost system using a color changing strip and a smart phone to measure salivary lactate. The bottleneck At this point, it is uncontroversial to say that science needs to stop using the PDF article as the unit of knowledge and currency. The unbearable slowness of scientific publishing, the profit motive and margins: I’m not saying anything new. The PDF also sucks because it’s hard to extract structured information, which makes it hard to do evidence synthesis. As a result, we do much less evidence synthesis than is needed. And evidence synthesis ultimately undergirds most policy and medical decision-making. I can see second-by-second real-time odds for any sporting or newsworthy event, but a school board can’t see the best evidence on whether their 8th graders should be taught algebra. As a society, we don’t treat this as an important problem. Again, not controversial. Not only is the problem well understood, but the solution has already been laid out. What we need is AI-assisted living evidence synthesis - (1) an open knowledge graph of atomic claims, (2) claims linked to evidence, (3) assessment and synthesis of each piece of evidence, and (4) continuous updating with new data. What few realize (yet) is that the technical capacity to build this vision for a significant portion of science already exists. Not only that, scientists and startup teams are already building many of these components. I know this because I’ve been surveying the space and talking to many of the builders. There are some missing pieces: for example, evaluations of how well some of the components work. But at this point, most of what’s missing is a fully end-to-end working integration of all of these parts. In the rest of this essay, I’m going to lay out all the parts of a working living evidence layer for science and who is working on them, and propose concrete next steps for building this system. What’s now possible The diagram above outlines the components of a living evidence synthesis platform, including some of the teams working on each component1. Scientific PDFs are processed into claims with associated evidence. The evidence is subjected to a forensic audit, methodological evaluation and robustness and reproducibility checks. Finally it’s given a weight in a continuously updating synthesis. What follows is a description and status of each component and a few of the teams working on them. Document understanding The first thing you need to be able to do is turn an article into structured data. Mostly that means parsing PDFs. There are often multicolumn layouts that confuse non-specialized PDF to text processing libraries. For scientific papers, there is the added complexity of parsing formulas and tables and figures. This is a really hot area - there are startups offering APIs, and it seems like a new open source package gets posted to Github every few weeks. What follows isn’t exhaustive. A package called GROBID was the state of the art for a while, they didn’t update their package for nearly two years until very recently. In the meantime reducto.ai released an AI powered PDF extraction API, PaddleOCR became popular, IBM released a model called Docling, and both Mistral and Gemini created models and libraries. I also know of at least one other well-funded psychology research group working on a paper parser. By contrast, there are few open evals in this space, with no extensive evals for complex table comprehension in particular. Nonetheless, I’m confident this will be a solved problem soon, given the combination of LLM advances and developer interest. Hypothesis level extraction There has been increasing interest in comprehending the extracted text of papers and linking information to evidence for each hypothesis. A lot of work has already been done. Trialstreamer (Marshall et al. 2020) and RobotReviewer LIVE (Marshall et al. 2023) demonstrated automated extraction of trial population, intervention, and outcome at scale on clinical RCTs. PaperQA2 (Skarlinski et al. 2024) and Ai2 ScholarQA (2024) extended this to retrieval-augmented question answering with citation grounding. Elicit, Consensus, and SciSpace operationalized claim-level extraction for end users. OpenEval (Booeshaghi et al. 2026) is the most recent and most ambitious: 1.96 million atomic claims extracted from 16,087 eLife manuscripts using Claude Sonnet 4.5, grouped into ~299,000 results, with LLM evaluations showing 81% agreement with human peer review on a 2,487-paper subset. None of these solutions link claims to test-statistics, as you would need to evaluate randomized controlled trials. This is why I built the evidence.guide API - to extract hypotheses and associated test statistics from behavioral science papers. The best public eval of this kind of extraction I’m aware of comes from the recent SCORE project - they had humans code thousands of psychology papers to extract their claims by hand. It would be extremely helpful to the world if all scientific PDFs were available as structured open data. I’ve been working to make this happen, both directly at Berkeley and through coordination with large entities I can’t yet speak of; as hard as it is to do, I think it’s possible2. Forensic audit A lot of work has been done on forensic audit, but some gaps remain. Of course, for biology papers that rely on images for evidence, there are a variety of tools (notably Proofig and ImageTwin) to spot anomalies. These are still well short of what sleuths like Elizabeth Bik can do on her own, but these tools are constant companions among fraud analysts. There’s someone working on auditing Excel files for anomalies, and a number of teams are automating numerical checks like GRIM and SPRITE, including Scrutiny project, the INSPECT-SR team as well as statcheck. The regcheck team is building a way to use AI to compare preregistrations to analyses in papers, to ensure there aren’t significant deviations. Nonetheless, there are many other kinds of anomalies to screen for, both public and less publicly known. And there are no formal evals for anomaly detection that I’m aware of. Still, there’s a lot to draw from in this space and I’m pretty certain we will be able to scan papers for most kinds of obvious anomalies in the near future. Methodological review This area has been white hot, though I fear for many of the startups in this space, because this capability may become commoditized. There are at least six different AI peer review companies, including Refine.ink, Reviewer3, ReviewerZero.ai, Q.E.D. Science, Paper Wizard, and Isitcredible. Coarse (a pun on refine) was also recently created as an open source alternative. These systems provide qualitative feedback on the content of papers, spotting methodological weaknesses and mathematical errors. They seem to work pretty well, and many academics report bitterly that they exceed the average quality of typical peer reviewers. But there are few evals here either. What evals exist so far involve using LLM-as-judge (circularity problems abound) or comparing against human reviews of questionable quality. What you’d ideally want is an eval that measures capturing known errors in papers3. Reproducibility and robustness Another active area has been using AI agents to automate computational reproducibility4 and robustness5 checks in papers that report numerical results. For more recent papers where data and code are available, AI agents can see whether they can re-run the analyses and produce the numbers reported in the published paper. In addition to a handful of individual academics who have been experimenting using Claude Code for this, the Institute for Replication is a leading group working on building an end to end system. The evals related to this problem are the most mature, with CORE-Bench (Siegel, Kapoor, Narayanan 2024) and PaperBench (OpenAI 2025) available to benchmark agents on this task. There is also work on getting AI agents to test alternative ways of analyzing the data to ensure the results are robust to small analytic design choices. Synthesis This is the most underdeveloped area where significant investment is required. Although some automated evidence synthesis systems exist — for example, otto-sr is building an AI agent to write systematic reviews — none of these incorporate the full range of paper level signals to weight evidence appropriately. Nor is there anything like an eval or a gold standard for a good systematic review. Arguably Cochrane reviews are the closest we have to gold standard human systematic reviews, though I’ve heard academics in the know complain about their uneven quality. A key question for a synthesis platform is how to weight anomalies and methodological issues in assessing the quality of a piece of evidence. This is an unsolved problem and one I’m very keen to work on. Continuous updating There are many pieces of basic infrastructure available for monitoring for new research and initiating updates. OpenAlex is the current open citation graph. Retraction Watch integrated into Crossref in October 2023. Scite tracks how citations support, contrast, or mention prior claims. The Living Evidence Network demonstrated continuous-update workflows in clinical guidelines. Engineering this is a relatively straightforward task. When you look over this technical architecture and all the progress being made, it’s hard not to be optimistic that a living guide to scientific evidence will be built. The stakeholders are ready The social infrastructure for this is starting to coalesce — it’s not just a pie in the sky academic exercise to imagine this coming into existence. Institutions like the Center for Open Science, the Institute for Replication, the INSPECT-SR, the Living Evidence Network and more are all working on scaling work to improve research quality. Funders are also aligned. The Sloan Foundation has funded living evidence work through COS. Coefficient Giving supports the Institute for Replication and COS. The Astera Institute and the Institute for Progress have shown interest in this space. NIH has established an Office for Replication and Reproducibility. Although there are (very unfortunately) serious headwinds in science funding generally, there is an active group of funders interested in metascience. A brief word about what I’ve been doing at RDI. First, as a Visiting Scholar at Berkeley I’ve been actively figuring out how a non-profit and a public university can conduct and make public the results of large-scale academic article data mining. With some of the money I raised from donors, I commissioned a legal analysis of recent case law and publisher text data mining (TDM) agreements in order to understand whether a massive open data mining of academic articles is possible (with caveats, it is). I’ve also been working to bring together stakeholders in this space, and identify gaps. I’ve also been doing some software development in this space, with more to come. A pilot proposal The assumption undergirding all of this is that an AI, given all this information, would make the right judgment about a scientific claim with lots of conflicting evidence, weighing all the factors appropriately. That’s the hypothesis we need to test. Randomized control trial research is the best place to focus on first. RCTs are used to make many of the important decisions in society - from medical trials to public policy changes. And they use a relatively uniform set of inferential statistics with lots of known and available diagnostics. Behavioral science experiments, within the broader realm of RCTs, should be first used as a testbed whose results can be generalized. Because behavioral science is at the vanguard of open science practices, replications abound (there are thousands of them) to serve as ground truth training data. Key Hypothesis Therefore the pilot would test, in behavioral RCTs that have been replicated, whether the quality of evidence for a claim can be used to accurately predict whether that claim will replicate. Secondary Hypotheses Compared to claims that replicated, non-replicated claims demonstrate a greater share of forensic anomalies in their source literatures. Hypothesis level claim and statistic extraction is accurate enough to scale living evidence without onerous human review costs. Replication prediction is more accurate than prediction markets6 or journal prestige. If all the different quality signals we gather do accurately predict which studies will replicate, then we can use that model to score evidence to power the living evidence layer. Why this is informative regardless of outcome If the pilot succeeds, the architecture extends to medical RCTs (where Living Evidence already operates and integration is mostly about claim representation), then to slices of basic biology with stable replication structure. If it fails, the field learns which quality signals are load-bearing and which ones metascience has oversold. Either result is a contribution to knowing what the literature supports. Implications for funders Because this burgeoning ecosystem of builders already exists, a well-informed philanthropic or government funder could play a crucial catalyzing role in bringing this future about. They could play at least three roles: creating open structured datasets, publishing open benchmarks and incentivizing the solving of key technical challenges. First, open archives of papers that the government maintains, like PubMed, could be turned into structured data amenable to large scale metascience and claim aggregation. I know the US government already has an interest in doing this, though some key open questions remain unanswered. How do you determine the best models and systems for accurately extracting information from papers? How can you establish a robust way to allow researchers to flag errors and correct them? And finally, how do you create a legal regime in working with publishers to maximize the scope of available papers? For the latter, a university or a private philanthropy may be better positioned to make structured data publicly available under journal subscription terms or fair use. Philanthropists or government funders could also coordinate to create or commission benchmarks that evaluate whether important problems have been solved. For example, an open benchmark for claim extraction from a range of different scientific article types would be extremely helpful. Ensuring the underlying data are accurate is vital for creating these evaluations. I’ve discussed opportunistically using various human-created datasets for this purpose, but a consistent problem is that errors in human data make it difficult for them to serve as a gold standard. Finally, with structured data and benchmarks available, the government or private philanthropy could use them to incentivize groups to develop machine learning systems that meet these benchmarks. Prizes are one potentially valuable tool for this. For example, you could establish a prize for a system that accurately updates a living meta-analysis for a small set of claims. Prizes are particularly useful as signals of problem importance, and can help create vibrant ecosystems of public and private research—see, for example the role the government played in kickstarting the current work on nuclear fusion. Conclusion The drawbacks of the current scientific publishing system are known. Scientists agree, metascientists agree, philanthropists agree: the published PDF plus citation graph isn’t the right substrate for maintaining a representation of the evidence base in science. The pieces needed to build the alternative either already exist or are rapidly taking shape. The community is forming around exactly this problem, with concrete partnerships and shared infrastructure. A pilot should start on behavioral science RCTs because that’s the slice of empirical science most amenable to legibility, where replication ground truth is richest, and where the failure modes are best documented. What’s been missing is the galvanizing mission to assemble these pieces into something that works. That’s what I’m proposing to build. *** 1 I have a broader field map that I’ll release publicly soon. This is me, building in public! 2 If this is something that you are excited about, please reach out and talk to me. 3 More on this very soon too! 4 This tests whether, given the code and the data, you can get the same statistics as reported in the published paper. 5 This tests whether the results are the same as a paper’s given alternative analytical decisions in conducting the analysis (like outlier omission). Closely related is the idea of a “multiverse” where you come up with many different ways of answering the same underlying research question with the same data, and test whether the results hold in all those alternative methods. There’s been work on the latter as well. 6 Some of the replications, e.g. those from the SCORE project, had paired the experiments with forecasts from prediction markets. So we get to look at this for free.
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