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Results for " make " 12,655 found 🔀 AI-powered Shuffle

This Web Tool Sabotages AI Chatbots By Making Them Really, Really Slow

Artist Sam Lavigne created ‘Slow LLM’ to make people question their dependence on tools like Claude and ChatGPT. Or at least, make them super annoying to use.

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Mar 23 • 11:20 AM EDT • Technology • 404media.co
New C8 Corvette Grand Sport Makes Surprise Debut at 12 Hours of Sebring

The first mid-engined Grand Sport dons a widebody and red hashmarks, with the car's full reveal coming later this week.

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Mar 23 • 10:50 AM EDT • Sports • caranddriver.com
Cowboys mock draft tracker: A trade might make sense early

How interested are you in trading back in the first round?

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Mar 23 • 9:00 AM EDT • Sports • sports.yahoo.com
Trump to Maria Bartiromo: Iran wants to make a deal badly, could be within 5 days or sooner

Maria Bartiromo reports that President Donald Trump says Iran ‘wants to make a deal badly’ as he orders a five-day pause on planned strikes against key infrastructure, signaling ongoing high-level talks and triggering a sharp market rebound.

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Mar 23 • 8:58 AM EDT • Business • foxbusiness.com
Danone to buy protein shake maker Huel as health nutrition craze drives demand shift

Merging the companies is an opportunity in fast-growing nutrition space, said Danone CEO Antoine de Saint-Affrique.

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Mar 23 • 8:14 AM EDT • Health • cnbc.com
Every NFL franchise's biggest position to improve, plus free agency and draft solutions

The Cowboys need to add to their defense, and they have the draft capital to make it happen.

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Mar 23 • 8:00 AM EDT • Sports • cbssports.com
How AT&T Business Powers TGL, a New Tech-Driven Golf League

Powered by AT&T Connectivity, TGL presented by SoFi preserves what makes golf great while transforming how fans experience it.

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Mar 23 • 8:00 AM EDT • Business • about.att.com
Crimson Desert Steam Reviews Jump to 'Mostly Positive' as Latest Patch Makes Significant Improvements

Crimson Desert Steam reviews are improving, moving up from ‘mixed’ to ‘mostly positive’ on Valve’s platform as developer Pearl Abyss releases game-changing updates.

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Mar 23 • 7:42 AM EDT • Technology • ign.com
Trump whistleblower Alex Vindman: ‘Sitting on the sidelines was not an option’

Democratic Senate hopeful says experience of being key witness in Trump’s first impeachment makes him right choice for Florida

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Mar 23 • 7:00 AM EDT • Politics • theguardian.com
UCLA tries to enjoy rare opportunity for Lauren and Sienna Betts

UCLA works to celebrate Lauren and Sienna Betts as successful sisters and individual playmakers pushing to help the Bruins win.

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Mar 23 • 6:30 AM EDT • Sports • latimes.com
Ohio lawmaker proposes election board changes after Delaware County dispute

Dispute at the Delaware County Board of Elections prompted a state lawmaker to propose changes to how county election boards work.

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Mar 23 • 6:03 AM EDT • Politics • dispatch.com
Data centers under scrutiny by California lawmakers as fears rise about health and energy impacts

Due to health and energy concerns, the California Legislature is considering bills to prohibit data centers from being exempted from the state's stringent environmental law and impose new tariffs on new major energy users that strain power supplies.

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Mar 23 • 6:00 AM EDT • Health • latimes.com
Exclusive | Lawmakers to Introduce Bipartisan Bill Banning Sports Bets on Prediction Markets

A bipartisan pair of U.S. senators are introducing legislation to prohibit CFTC-regulated entities from listing contracts related to sporting events.

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Mar 23 • 5:30 AM EDT • Sports • wsj.com
A new twist on matter? Strange 'Half-Mӧbius' molecule has rare properties chemists have never seen before

Chemists created a strange 'half-Mӧbius' molecule, where electrons twist freely out of place to make a continuously looping surface.

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Mar 23 • 5:00 AM EDT • Science • livescience.com
Crimson Desert Update Makes Control Improvements, Eases The Difficulty

Crimson Desert's latest update introduces early player-driven improvements, including new storage options, combat balance tweaks, and expanded fast travel.

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Mar 23 • 4:03 AM EDT • Technology • gamespot.com
Toto Wolff: Mercedes team principal wary of 'politics' as Charles Leclerc makes 'extremely strong' Silver Arrows claim
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Mar 23 • 2:00 AM EDT • Politics • skysports.com
Bucks, Clippers still hoping to make playoff runs

The Los Angeles Clippers will welcome an old friend back into town Monday when former head coach Doc Rivers and his current team, the Milwaukee Bucks, make a visit to Inglewood, Calif.

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Mar 23 • 1:46 AM EDT • Sports • cbssports.com
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State lawmakers debate new round of business tax cuts

Rep. Joe Sweeney, R-Salem, and Sen. Donovan Fenton, D-Keene, discussed their support and opposition to House Bill 155, which would reduce the business enterprise tax from 0.55% to 0.50%.

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Mar 22 • 11:27 PM EDT • Business • wmur.com
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Does PBS ‘Count of Monte Cristo’ Make Big Book Changes?

A recap of Episode 1 of the Sam Claflin and Jeremy Irons-led adaptation.

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Mar 22 • 11:00 PM EDT • Entertainment • northwestgeorgianews.com
Simona Martin: Colorado’s data center boom needs public health guardrails

As AI infrastructure expands across the state, lawmakers face a choice about who bears the costs and risks.

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Mar 22 • 11:00 PM EDT • Health • boulderreportinglab.org
Two new features are officially announced today for the Google Messages app

Google makes it easy to notify members of an RCS group chat while your wife isn't the only reason you're taking out the trash.

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Mar 22 • 10:46 PM EDT • Technology • phonearena.com
A DNA test ruled him out. He was convicted of murder anyway.

Forensics has its share of high-profile problems. There’s phony “junk science,” like bogus bite-mark and blood spatter analyses that have sent innocent people to jail. And there’s the steady drumbeat of lab scandals, where analysts make up results. But there’s a subtler and more pervasive problem at work in many cases: lab analysts and lawyers who take perfectly legitimate science and twist it. Globe Opinion is exploring these distortions with a series we’re calling “Twisted Science.” And there may be no better place to start than with the case of Terrel Barros.

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Mar 22 • 9:57 PM EDT • Science • bostonglobe.com
Joe Kent says he wants Donald Trump to hear MAGA opposition to Iran war

It’s a concerted effort, Kent said, to rally members of the president’s Make America Great Again movement and ensure he hears dissenting voices.

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Mar 22 • 8:52 PM EDT • Politics • detroitnews.com
Women's March Madness live updates, scores: LSU makes history in NCAA tournament; Minnesota stuns Ole Miss to advance to Sweet 16
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Mar 22 • 5:19 PM EDT • Sports • sports.yahoo.com
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‘We’ve got some unfinished business’: Corey Gipson reflects on historic Austin Peay season

Austin Peay men's basketball head coach Corey Gipson recently reflected on his 2025-26 season and revealed what makes Clarksville special.

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Mar 22 • 3:29 PM EDT • Business • clarksvillenow.com
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CBS analyst picked against Purdue basketball. Here's what he thinks of Sweet 16 vs Texas

Boilermakers fans were critical of Seth Davis for his pick proven wrong after Purdue beat Miami. Here's what he thinks of the Sweet 16 game vs Texas.

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Mar 22 • 3:15 PM EDT • Sports • indystar.com
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The OG Four-Door Porsche Sports Sedan Wasn't Even Built By Porsche

In 1967, a Texas-based car dealer wanted a four-door Porsche 911 S. Porsche wouldn't make it, so he turned to coachbuilders for help.

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Mar 22 • 3:05 PM EDT • Technology • jalopnik.com
Student researchers bring Kentucky State University science to Posters-at-the-Capitol

With lawmakers just steps away, three Kentucky State University undergraduates presented research on cattle health, soil amendments and food safety at the Capitol Annex on March 5, bringing student-led agricultural […]

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Mar 22 • 3:00 PM EDT • Science • state-journal.com
Welcome to allergy season. Here's how to protect yourself

Where you live, what you're allergic to and your lifestyle can make a big difference when it comes to the severity of your allergies.

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Mar 22 • 2:47 PM EDT • Health • abc7ny.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
What’s happening in Vegas arts entertainment this spring

Festivals, concerts, sporting events and more: Make plans with our entertainment calendar.

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Mar 22 • 12:41 PM EDT • Entertainment • neon.reviewjournal.com
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Moms start business to make baby carriers more inclusive, fun
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Mar 22 • 12:23 PM EDT • Business • cbsnews.com
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Assemblywoman Alexandra Macedo says César Chávez allegations are "just the tip of the iceberg"

California lawmakers this upcoming week are set to move quickly to rename César Chávez Day to Farmworkers Day ahead of the holiday that takes place every year on March 31.

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Mar 22 • 11:25 AM EDT • Politics • kcra.com
Bash: Trump celebrating Mueller’s death ‘not a surprise, but that doesn’t make it okay’
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Mar 22 • 10:26 AM EDT • Politics • cnn.com
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Colorado lawmakers can pass “Alyssa’s Act” to help coaches and parents monitor mental health (Opinion)

In 2019, we lost Alyssa after she struggled with her mental health following a series of concussions. We later learned that concussions can be linked to serious mental health challenges and an increase in suicide, especially in young people.

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Mar 22 • 7:01 AM EDT • Health • denverpost.com
The case against the Senate filibuster no Republican can make

How to put Congress, not the president, in the U.S. politics driver’s seat: End the 60-vote tradition.

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Mar 22 • 6:00 AM EDT • Politics • washingtonpost.com
The Supreme Court Could Make it Harder to Vote by Mail in the Midterms

The Republican National Committee wants to toss ballots arriving after Election Day. Critics say thousands of votes — a majority cast by Democrats — are at stake.

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Mar 22 • 5:00 AM EDT • Politics • nytimes.com
‘We can create hype’: H&M’s UK boss on its commitment to the high street

As the chain marks 50th anniversary in Britain, Karen O’Rourke explains what makes it stand out against cut-price rivals

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Mar 22 • 4:00 AM EDT • Business • theguardian.com
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Politics: Iowa Senate majority leader outlines plans for coming weeks

Second funnel week concluded in the Iowa Legislature, meaning that lawmakers’ focus can return to funding, appropriations and other types of specific bills that don’t respond to the Legislature’s self-imposed

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Mar 22 • 2:00 AM EDT • Politics • telegraphherald.com
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No. 11 Texas becomes 6th First Four team to make NCAA tournament's Sweet 16 with upset win over No. 3 Gonzaga
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Mar 21 • 9:40 PM EDT • Sports • sports.yahoo.com
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Microsoft says it'll make Windows 11 a calmer OS with fewer upsells or ads, as it tries to win back users

Microsoft has now confirmed it’s scaling back “upsells” (or ads/recommendations) in Windows 11, as it tries to win back users.

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Mar 21 • 8:03 PM EDT • Technology • windowslatest.com
Reliever Kyle Backhus hopes to make good on Bryce Harper's text message

Bryce Harper texted Kyle Backhus the day he was traded to the Phillies. Now the side-arming lefty is pitching his way onto the Opening Day roster.

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Mar 21 • 2:24 PM EDT • Sports • nbcsportsphiladelphia.com
Here’s how Va. lawmakers suggest the next state budget handle federal health care funding fallout

Spanberger will mull theirs and former Gov. Glenn Youngkin’s budget proposals ahead of a reconvened session on April 23.

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Mar 21 • 1:10 PM EDT • Health • wtop.com
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Franklin Templeton CEO Jenny Johnson on the values needed to keep a billion-dollar business in the family

Jenny Johnson is CEO of $12 billion family-run asset management business Franklin Templeton, which oversees nearly $2 trillion in assets. Growing the company and succeeding in the role took everyone in the family, including herself, putting their egos aside.

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Mar 21 • 11:00 AM EDT • Business • cnbc.com
What to know about Jaloni Cambridge, Ohio State's star in March Madness

Ohio State's Jaloni Cambridge makes her presence known in the paint and with pull-up jumpers. Here's what to know about her in the NCAA Tournament.

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Mar 21 • 9:27 AM EDT • Sports • usatoday.com
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Country music star wants a shot at Super Bowl Halftime Show: ‘Make the call’

It's been a while since a country music star landed the gig.

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Mar 21 • 7:35 AM EDT • Entertainment • pennlive.com
The US Senate could soon set a historic first: Three Black women serving at the same time

In the days after winning the Democratic nomination for Senate, Illinois Lt. Gov. Juliana Stratton spoke to the two women with whom she could make history next year.

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Mar 21 • 7:00 AM EDT • Politics • cnn.com
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When health insurance costs $2,500 per month, families make tough choices

A self-employed couple already had to dip into retirement savings for health costs. Now, they are skipping vacations and canceling streaming to afford health insurance.

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Mar 21 • 7:00 AM EDT • Health • npr.org
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Inside Fidji Simo's quest to make OpenAI profitable

Nearly 8 months into her job as OpenAI's CEO of Applications, Fidji Simo must start minting money while convincing staffers the mission hasn't changed.

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Mar 21 • 6:01 AM EDT • Business • businessinsider.com
Denver Broncos mock draft: Post-Jaylen Waddle trade

We’re coming back to the mock draft simulator this weekend. The Denver Broncos said ‘f dem picks’ and acquired wide receiver Jaylen Waddle from the Miami Dolphins this week. That trade provided a big boost to the offense, but it will make their 2026 NFL Draft much more challenging. With the reduction in draft capital, […]

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Mar 21 • 6:00 AM EDT • Sports • sports.yahoo.com
List: The 6 bills that lawmakers have proposed on prediction markets

From banning lawmakers from Polymarket and Kalshi, to getting rid of sports trading, lawmakers have a variety of proposals for prediction markets.

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Mar 21 • 5:57 AM EDT • Business • businessinsider.com
TSA agents are working without pay. Here's how much they usually make.

TSA agent pay starts at around $40,000 annually, but they can earn six figures as they gain experience and by living in more expensive cities.

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Mar 21 • 4:01 AM EDT • Business • businessinsider.com
Nebraska lands the commitment of 3-star athlete Kaden Howard

The feel-good momentum surrounding the Nebraska athletic department continues to build following the men’s basketball team’s first-round NCAA Tournament victory—and it’s now carrying over onto the recruiting trail. The Cornhuskers have secured a commitment from 3-star athlete Kaden Howard, a 5-foot-10, 160-pound playmaker out of Miami, Florida. Howard picked Nebraska over Louisville, West Virginia and […]

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Mar 21 • 2:48 AM EDT • Sports • sports.yahoo.com
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Israel deliberately targeting medical facilities in south Lebanon, say health workers

Medics and officials say there is systematic use of double-tap strikes in campaign to make the south uninhabitable

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Mar 21 • 2:00 AM EDT • Health • theguardian.com
Thompson makes 30 stops in Capitals win over Devils

Jesper Bratt scored for the Devils, extending his point streak with three goals and four assists over his last seven games. Jake Allen stopped 26 shots. It was the third meeting between the teams and the first that didn't require extra time.

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Mar 20 • 11:20 PM EDT • Sports • sports.yahoo.com
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Eagles Predicted to Make Perfect Selection in 2026 NFL Draft

The Philadelphia Eagles have had a nice offseason and that should only continue in the NFL Draft.

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Mar 20 • 9:27 PM EDT • Sports • sports.yahoo.com
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Scientists turn probiotic bacteria into tumor-hunting cancer killers

Scientists have engineered probiotic bacteria to act as tumor-seeking drug factories. In mice, these bacteria infiltrated tumors and produced a cancer-fighting drug right where it was needed. This targeted approach could make treatments more effective and reduce side effects. More research is needed before it can be tested in people.

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Mar 20 • 8:00 PM EDT • Science • sciencedaily.com
Microsoft Is Finally Ready to Make Windows 11 Less Terrible After Bloating It With AI Crap

Less Copilot, better search, and more taskbar customization are apparently in the pipeline.

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Mar 20 • 6:45 PM EDT • Technology • gizmodo.com
iOS 26.4: Top 10 New Features Coming to Your iPhone

iOS 26.4 isn't the major update with new Siri features that we hoped for, but there are some useful quality of life improvements, and a little bit of fun with an AI playlist generator and new emoji characters. Playlist Playground - Apple Music has a Playlist Playground option that lets you generate playlists from text-based descriptions. You can include moods, feelings, activities, or make up something entirely nonsensical and let the AI figure out what you mean.

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Mar 20 • 5:44 PM EDT • Technology • macrumors.com
Microsoft's 7-point plan to fix Windows 11 makes macOS Tahoe look golden

macOS Tahoe may have its critics, but even Microsoft is struggling to find things to like about Windows 11. The...

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Mar 20 • 3:47 PM EDT • Technology • 9to5mac.com
Amid soaring prices, Maryland Republicans make political push for gas tax holiday

Maryland House and Senate Republicans said Thursday they will press for a 30-day gas tax holiday to ease skyrocketing gas prices spawned by the Iran war.

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Mar 20 • 2:54 PM EDT • Politics • wtop.com
Project Hail Mary's science and friendship-driven plot makes for a great watch: review
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Mar 20 • 1:04 PM EDT • Science • cbc.ca
Left's political targeting makes a comeback as prominent Democrats advocate for harassment

Fox News contributor Ben Domenech criticizes Democrats including Gov. JB Pritzker and Rep. Maxine Waters over rhetoric targeting Republican and Trump officials on ‘The Faulkner Focus.’

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Mar 20 • 12:43 PM EDT • Politics • foxnews.com
Scientists Make a Major Breakthrough in Solving a Hair-Raising Mystery About Static Electricity

The findings can help explain the physics behind phenomena like volcanic lightning

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Mar 20 • 11:29 AM EDT • Science • smithsonianmag.com
High-Protein Mac & Cheese, Broccoli Chips Target Health-Conscious Diners

Packaged food is getting a makeover with options that are aligned with today’s eating habits.

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Mar 20 • 9:10 AM EDT • Health • bloomberg.com
Spiking diesel prices force WA businesses to make tough choices

Drivers, trucking firms and other shipping companies worry the rise in diesel prices will reignite inflation and force many operators out of business

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Mar 20 • 9:00 AM EDT • Business • seattletimes.com
Panthers make pair of returns official

The returns of two Panthers were announced on Thursday.

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Mar 20 • 8:35 AM EDT • Sports • sports.yahoo.com
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Phillies News: Dylan Moore, J.T. Realmuto, New Concessions

The Phillies have a roster decision to make, Moore or less. Also, ice cream!

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Mar 20 • 7:00 AM EDT • Sports • sports.yahoo.com
Mets predicted to make blockbuster Tarik Skubal trade with Tigers

This would come as a change of pace after the offseason.

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Mar 20 • 6:47 AM EDT • Sports • sports.yahoo.com
Marmite maker Unilever in talks to merge food business with US-based McCormick

Group, which also owns Dove and Hellmann’s, will focus more on personal care products if deal agreed

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Mar 20 • 5:40 AM EDT • Business • theguardian.com
Here’s how Va. lawmakers suggest the next state budget handle federal health care funding fallout

More than 2 million Virginians rely on state social services like Medicaid and the Supplemental Nutrition Assistance Program, while about 400,000 Virginians get their health insurance through the state marketplace.

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Mar 20 • 5:25 AM EDT • Health • virginiamercury.com
Unilever Confirms Talks on McCormick Offer for Food Business

Unilever Plc said it’s in discussions to sell its food business to McCormick & Co. in a major shift for the maker of Hellmann’s mayonnaise.

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Mar 20 • 3:16 AM EDT • Business • bloomberg.com
Who Should Be England’s Number 10 at the World Cup?

The 2026 FIFA World Cup is fast approaching, and England manager Thomas Tuchel has some huge decisions to make. Former boss Gareth Southgate came in for major criticism from supporters for continually...

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Mar 20 • 2:15 AM EDT • Sports • sports.yahoo.com
March Madness scores, winners and losers: North Carolina, Wisconsin collapse, Nebraska makes history

The Cornhuskers celebrated a program first, while the Tar Heels and Badgers are in the news for all the worst reasons

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Mar 19 • 10:32 PM EDT • Sports • cbssports.com
Mid-Ohio Valley Entertainment Commission hosts training session on film production

The Mid-Ohio Valley Entertainment Commission brought together film enthusiasts for a film crew training event at Marietta College on Sunday. The event sought to promote creativity and inspire filmmakers in the region. The event was originally scheduled for the entirety of the weekend but due to weather, the session was condensed to Sunday only. MOV […]

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Mar 19 • 8:00 PM EDT • Entertainment • mariettatimes.com
Mid-Ohio Valley Entertainment Commission hosts training session on film production

MARIETTA – The Mid-Ohio Valley Entertainment Commission brought together film enthusiasts for a film crew training event at Marietta College on Sunday. The event sought to promote creativity and inspire filmmakers in the region. The event was originally scheduled for the entirety of the weekend but due to weather, the session was condensed to Sunday […]

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Mar 19 • 8:00 PM EDT • Entertainment • newsandsentinel.com
Unilever in talks to combine food business with McCormick, WSJ reports

Unilever is in ​talks to separate its food ‌business and combine it with spice maker McCormick in an all-stock ​deal which could come ​within weeks, the Wall Street ⁠Journal reported on Thursday, citing ​sources.

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Mar 19 • 7:28 PM EDT • Business • reuters.com
Unilever in Talks to Combine Food Business With McCormick, Report Says

Unilever Plc, the maker of Hellmann’s mayonnaise, is in talks to combine its food business with McCormick & Co., according to a report in the Wall Street Journal citing people familiar with the matter.

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Mar 19 • 7:22 PM EDT • Business • bloomberg.com
Crimson Desert Day One Update Goes Live in Full on PC, in Part on Console — Check Out the Patch Notes

Crimson Desert has launched across all platforms, and with it comes a day one update that makes some significant improvements to the game, some balance changes, and various fixes. Pearl Abyss recommended players download the patch “for the best experience.” Check out the patch notes.

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Mar 19 • 6:45 PM EDT • Technology • ign.com
New dispute emerges around Subnautica 2’s early access release

Lawyers for the ousted—and now partially reinstated—leadership team of Unknown Worlds, the studio behind Subnautica 2, are crying foul over news that the game will be released into early access in May. The release announcement earlier this week was made improperly, potentially “damaging the game and sowing additional confusion among the Subnautica community,” the lawyers said in a letter sent on Tuesday to Vice Chancellor Lori Will of Delaware’s Court of Chancery. In their letter, the lawyers also floated the idea of asking Will to find Krafton in contempt of the court’s ruling. The letter was sent just one day after Will’s bombshell ruling that publisher Krafton had breached its contract with Unknown Worlds’ executive team, when it fired them last June. The new issue isn’t necessarily the May early access timeframe, but how the news was announced. The letter and Krafton’s response have not been previously reported. A quick recap of prior events: Subnautica 2 is an unreleased, underwater survival adventure and the most-wishlisted game on Steam. Last year, longtime Unknown Worlds CEO Ted Gill, along with studio co-founders Charlie Cleveland and Max McGuire, were fired by Krafton. They swiftly sued, saying the publisher had terminated them to avoid paying out up to $250 million in potential performance-based bonuses. The studio leaders had hoped to earn that with an early access release of the game, which Krafton had blocked. The publisher argued in court that Subnautica 2 wasn’t ready, which the ousted execs disputed. On Monday, Will ruled that Krafton had violated its contract, firing the execs to avoid the performance payouts, and that it had to reinstate Gill and give him full authority over any early access release for Subnautica 2. On Tuesday, IGN reported on a new memo issued that day to Unknown Worlds staff by Steve Papoutsis, the executive Krafton had put in charge of Unknown Worlds after the 2025 firings. In the note, Papoutsis said that Subnautica 2 had passed a key development milestone “last week” and that he and Krafton had determined the game “is ready for Early Access release in May.” This news appeared to catch the lawyers for Gill, Cleveland and McGuire by surprise. On Tuesday night, they sent a letter to Will expressing “serious concerns” about whether it would be possible to forge an agreement with Krafton consistent with the judge’s order. Papoutsis’ memo was a problem, they wrote. He didn’t have the authority to declare anything about Subnautica 2’s release. As of 9am ET on Monday, March 16, the effective date of Will’s order, Papoutsis wasn’t CEO of Unknown Worlds. Gill was. And, per Will’s order, only Gill could make Subnautica 2 release decisions. They continued: Krafton self-servingly announced the launch without any regard to its impact on the game, the team, or the community—let alone this Court’s Opinion. Announcing the release of a game is momentous, and it is typically accompanied by significant marketing activity, fanfare, and community coordination. And most importantly, the announcement is carefully designed to maximize excitement for the game. That entire process was supposed to be driven by Mr. Gill. However, in defiance of the Court’s Opinion, Krafton has now taken that away, further damaging the game and sowing additional confusion among the Subnautica community. The lawyers speculated that Krafton had “intentionally leaked” Papoutsis’ memo and then issued an official statement to confirm the leak. Game File is a reader-supported publication. My reporting is only possible through support from readers like you. To support my work, consider becoming a free or paid subscriber. Subscribe On Wednesday, lawyers for Krafton defended their client in their own letter to vice chancellor Will, saying nothing they did violated her order nor showed contempt: Papoutsis’s message was simply celebrating the UW employees’ efforts toward a past event: Krafton’s pre-Opinion determination that Subnautica 2 was ready for Early Access release. There was nothing improper about conveying the results of the milestone review or thanking the development team for their dedication and talent. They added that Gill could still make his own call about Subnautica 2’s release: In his role as CEO, Gill will be able to assess independently his views on the state of Subnautica 2 and the appropriate release schedule; nothing in Papoutsis’s message alters Gill’s authority or discretion. Vice chancellor Will has not responded to the letters and doesn’t necessarily have to. Both parties were previously ordered by Will to confer this week and submit a proposed judgment consistent with her ruling. The letter from Gill’s attorney’s this week doesn’t indicate whether he would or would not support a May release for Subnautica 2. But it could limit his options. And, if Gill’s lawyers are right, the lack of marketing fanfare around the leak of the May date could dull the launch of the game. Any harm to Subnautica 2’s launch is an extra sensitive issue given the context of the legal dispute: millions of dollars of payouts are on the line, tethered to the scale of the game’s initial performance. In her ruling on Monday, Will noted that there was obvious “bad blood” between Gill’s side and Krafton but that the two would need to work together: “They can—and must—act in good faith to navigate their remaining contractual relationship.” Item 2: A new kind of couch co-op game A highlight of GDC each year is the Alt.Ctrl showcase that features games played with extremely experimental controllers. Perusing this year’s offerings last Friday, I found a game controlled with giant scissors, another with big toothbrushes and one that amounted to dumpster diving. My favorite was Pivot, a co-op game about collectively maneuvering a couch. It was developed by students at the University of Utah’s masters of arts and engineering games program. Players lift and tilt the physical couch in order to control the position of a virtual one. That virtual one is moving through an obstacle course on-screen, while being pursued by a giant skull. Developer Nishant Verma told me at GDC that the couch is made of styrofoam (this became more evident as I watched!) and that the name was a riff on an episode of the sitcom Friends. Item 3: In brief… 🚫 Ubisoft is laying off more than 100 workers at its Red Storm studio, as the North Carolina location known for decades for its Tom Clancy games, ceases in-house game development, VGC reports. 👀 On Monday, Nvidia’s revealed its DLSS 5 AI-driven graphics technology that purports to improve game graphics… and it has been roasted about it by the media and the online gaming public for the remainder of the week. The tech changed the faces of characters in footage from Resident Evil Requiem, Hogwarts Legacy and EA Sports FC, drawing accusations of giving carefully art-directed games the generic look of AI “slop.” Nvidia CEO Jensen Huang had said on Monday that “DLSS 5 is the GPT moment for graphics—blending handcrafted rendering with generative AI to deliver a dramatic leap in visual realism while preserving the control artists need for creative expression.” By mid-week, Huang was telling Tom’s Hardware that the new tech’s critics were “completely wrong” because game-makers could still “fine-tune the generative AI” to suit their game’s aesthetics.

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Mar 19 • 5:28 PM EDT • Technology • gamefile.news
2026 March Madness: What Makes an NCAA Tournament Champion?

March Madness is here, and FOX Sports Research has done a historical deep-dive into the characteristics that make up a tournament champion.

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Mar 19 • 5:25 PM EDT • Sports • foxsports.com
Democrats Demand Answers on Jared Kushner’s Mideast Business Dealings

Two prominent lawmakers wrote to the White House and Mr. Kushner after The New York Times revealed private fund-raising efforts by President Trump’s envoy in the region.

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Mar 19 • 4:47 PM EDT • Business • nytimes.com
‘Dune’ tried to warn us against AI

‘Thou shalt not make a machine in the likeness of a human mind.’

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Mar 19 • 4:45 PM EDT • Science • popsci.com
Huge Trump Iran war funding request faces stiff opposition in Congress

Lawmakers estimated the war is costing $1 billion to $2 billion per day.

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Mar 19 • 3:43 PM EDT • Politics • detroitnews.com
MLB further embraces sports betting in deal with prediction platform Polymarket

MLB is currently mired in a betting scandal involving several pitchers. MLB and Polymarket execs say deals like this make the game safer.

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Mar 19 • 2:59 PM EDT • Sports • nytimes.com
Florida GOP’s divisions, cancel culture and Alligator Alcatraz: IFP

Turns out Florida state lawmakers can't approve budget, but they do like cancel culture. And how much has the state spent on Alligator Alcatraz?

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Mar 19 • 2:50 PM EDT • Politics • usatoday.com
Cracks emerge in GOP over Iran war cost as administration floats more than $200B request to Congress

Cracks are emerging among congressional Republicans over the Iran war with key lawmakers skeptical about spending hundreds of billions of dollars to prolong the conflict and several refusing to support any money without a clear White House strategy.

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Mar 19 • 2:33 PM EDT • Politics • cnn.com
Figma stock sinks after Google 'vibe design' tool gets update

Google's Stitch AI tool is the latest shot across the bow of software makers, as AI companies roll out features directly challenging their products.

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Mar 19 • 12:49 PM EDT • Business • businessinsider.com
🙂 Positive (50%)
Russia adds fiber-optic wires to Molniya drones, makes them unjammable

Fiber-optic cables have typically been used for smaller quadcopters. Now, the practice is being extended to larger fixed-wing drones.

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Mar 19 • 11:59 AM EDT • Business • businessinsider.com
Free Play Days – Sea of Thieves, Totally Reliable Delivery Service, Trailmakers, Hell Let Loose and Firefighting Simulator: Ignite

Free Play Days - hop into Sea of Thieves, Totally Reliable Delivery Service, Trailmakers, Hell Let Loose and Firefighting Simulator: Ignite this weekend.

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Mar 19 • 11:00 AM EDT • Technology • news.xbox.com
The Politics Hour: VA State Sen. Scott Surovell & WAMU's Alex Koma

WAMU's Alex Koma discusses the latest in D.C.'s big elections, including the mayoral race. And Virginia state Senate Majority Leader Scott Surovell on the General Assembly failing to make a deal on the budget.

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Mar 19 • 10:31 AM EDT • Politics • wamu.org
Science explains why removing adhesive tape makes that unbearable squeaky noise

Scientists discover why adhesive tape makes that squeaking noise when peeled off: tiny shock waves produce the high-pitched sound.

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Mar 19 • 10:30 AM EDT • Science • earth.com
RFK Jr. makes food sound like a miracle drug. Researchers say he often overstates the science

In the Trump administration’s campaign to promote healthy eating, Robert F. Kennedy Jr. has not stopped at his slogan urging people to “eat real food” to prevent disease. In recent speeches and…

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Mar 19 • 9:02 AM EDT • Science • wtop.com
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RFK Jr. Makes Food Sound Like a Miracle Drug. Researchers Say He Often Overstates the Science

In the Trump administration’s campaign to promote healthy eating, Robert F. Kennedy Jr. has not stopped at his slogan urging people to “eat real food” to prevent disease. In recent speeches and podcast appearances, the nation’s health secretary also has claimed that diet can “cure” schizophrenia and ...

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Mar 19 • 9:02 AM EDT • Science • usnews.com
RFK Jr. Makes Food Sound Like a Miracle Drug. Researchers Say He Often Overstates the Science

In the Trump administration’s campaign to promote healthy eating, Robert F. Kennedy Jr. has not stopped at his slogan urging people to “eat real food” to prevent disease. In recent speeches and podcast appearances, the nation’s health secretary also has claimed that diet can “cure” schizophrenia and ...

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Mar 19 • 9:02 AM EDT • Health • usnews.com
Will Iowa lawmakers reach a property tax deal before session adjourns?

Iowa lawmakers and Gov. Kim Reynolds are still working to \

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Mar 19 • 8:24 AM EDT • Politics • desmoinesregister.com
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Opinion: The dirty politics behind Judge Torgerson’s censure

Doug McMurdo: If Utah lawmakers were really worried about “the children,” where was their outrage when Stuart Adams ushered in a change to Utah’s statutory sexual assault law to protect a relative? It’s hypocrisy, plain and simple.

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Mar 19 • 8:00 AM EDT • Politics • sltrib.com
German Health Minister Nina Warken and WHO Hub in Berlin highlight 2025 achievements

Germany’s Federal Minister of Health, Nina Warken, visited the WHO Hub for Pandemic and Epidemic Intelligence in Berlin today to review progress and launch its 2025 Annual Report. The report highlights advances in using artificial intelligence, data science and pathogen genomics to strengthen global preparedness for future pandemics.In 2025, the WHO Hub in Berlin worked with more than 160 Member States and over 190 partners to help countries and organizations develop new systems and tools to detect and understand new public health threats as quickly as possible, whenever and wherever they occur.BMG to confirm whether they wish to contribute a quote. “Detecting outbreaks early is one of the most effective ways to save lives and prevent epidemics from becoming global crises,” said Federal Minister of Health Nina Warken. “Germany is proud to host and support the WHO Hub for Pandemic and Epidemic Intelligence. Its work strengthens our safety at home and helps protect people worldwide.”Artificial intelligence is increasingly transforming the detection of outbreaks. In 2025, the Hub launched an upgraded version of the Epidemic Intelligence from Open Sources (EIOS) system, which uses enhanced AI functions to scan global online information in real time and help experts quickly identify unusual health events. The system is now used by 120 countries.To better anticipate health threats, countries need information beyond traditional health data. The Hub supports countries in implementing Collaborative Surveillance, which integrates data on climate, animals, travel, and population movement to provide a more comprehensive and real-time understanding of health threats.The Hub also expanded global access to pathogen genomics, which helps scientists detect new pathogens, such as viruses and bacteria, understand how they spread and how dangerous they may become. Through the International Pathogen Surveillance Network (IPSN), the WHO Hub in Berlin worked with 309 partners in 101 countries to expand access to these technologies.“We are in a new era of global health threats, and we need new tools to face tomorrow’s challenges,” said Dr Chikwe Ihekweazu, Executive Director of the WHO Health Emergencies Programme. “The WHO Hub in Berlin helps countries use data and technology more effectively so they can identify risks earlier and respond faster. No country can address these threats alone. Strong cooperation remains our best defence.”“Berlin offers an ideal environment for our work. We collaborate closely with world-leading institutions such as the Robert Koch Institute and the Charité Center for Global Health,” said Dr Oliver Morgan, Head of the WHO Hub for Pandemic and Epidemic Intelligence. “Germany has supported the WHO Hub since its establishment, and we are pleased to welcome Federal Minister Nina Warken to the Hub today. This strong partnership helps us advance innovation in pandemic and epidemic intelligence and better support countries to prepare for future health threats.”The Hub is expanding the use of advanced analytics and mathematical modelling to forecast how outbreaks may develop and to assess which response measures are most effective. Through its Collaboratory, the Hub connects modelers and analysts with governments to ensure their work addresses real public health needs. In 2025, the community grew to 1300 members from 50 countries and 200 institutions. An AI-powered pandemic simulator, currently in the prototyping phase, will help decision-makers compare outbreak scenarios and help identify effective disease control measures.

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Mar 19 • 8:00 AM EDT • Health • who.int
Mathews Local School board freezes coach salaries, no sports cuts

Superintendent Russell McQuaide decided tonight that the programs can stay, but warned that diminishing funding will force them to make tough decisions in the future.

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Mar 19 • 6:38 AM EDT • Sports • wfmj.com
Memphis People in Business for March 19, 2026

A look at promotions, hirings, movers and newsmakers in the Memphis area business scene.

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Mar 19 • 6:01 AM EDT • Business • commercialappeal.com
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