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Flory Bidunga reportedly commits to Louisville basketball, Pat Kelsey
Flory Bidunga, who many considered to be the top player in the NCAA transfer portal, has reportedly picked Louisville basketball and coach Pat Kelsey.
Duke hosting Kansas transfer Flory Bidunga on visit
Duke is set to host top portal prospect Flory Bidunga out of Kansas as he evaluates NBA Draft interest and potential landing spots.
Minnesota politics: Previewing governor's race and Iran war impact | FOX 9 Minneapolis-St. Paul
Political analyst Blois Olson takes a look ahead to what could be the most expensive legislative race in Minnesota history. He also examines how the war in Iran could impact voting choices in rural areas.
2026 Cubs Heroes and Goats: Game 14
The Cubs come from behind, only to lose 4-3 in extra innings.
Chris Bell NFL Draft Profile
Doug watches the college film to assess Chris Bell's strengths and weaknesses as well as what it likely means for his NFL future.
Three-star recruit Trenton Blaylock narrows list to final eight
Trenton Blaylock is the brother of Oklahoma running back Tory Blaylock.
Bengals News (4/11): Looking back 30 Years
One of the Bengals best draft picks in their team’s history occurred three decades ago.
Yankees news: Volpe slated to start upon return
Volpe expected to retake starting gig once healthy; flaws emerge as Yanks nosedive from hot start; Average salary in MLB rises; Mike Ford retires, takes role in Rays’ front office.
Burnley XI vs Brighton – Predicted lineup and team news
Burnley host in-form Brighton today, aiming to narrow a ten-point gap to Premier League safety.The Clarets have moved closer to relegation after winning only once in 22 league games. Manager Scott Par...
Splashdown party at Chabot Space and Science Center
The Chabot Space and Science Center in Oakland hosted some of the brains behind the Artemis II operation from Nasa for a community-wide watch party of Orion's splashdown.
Could treble hero Dante return to Bayern Munich as coach?
Pep Guardiola's favorite player might return soon.
New health service lets Mountain Brook, Vestavia, Homewood residents skip the long waits
A new house call service is coming to Vestavia Hills, Homewood and Mountain Brook.
Boston 25 News
Spring sports season is here, and for millions of kids, that means teammates, competition, and time on the field, and the benefits can last a lifetime.
Spring Marlin Business Conference: Leadership Reimagined
Join the next generation of leaders April 13–16 for a week of innovation, insight, and opportunity
Jayson Tatum scores 24 for Celtics in first game at Madison Square Garden since Achilles injury, but Knicks win
G7 One Health Summit launches global diagnostics initiative, and other health stories
Top health news: G7 launches global diagnostics initiative; Five actions to end tuberculosis; Middle East conflict impacts healthcare.
Scientists create new type of encryption that protects video files against quantum computing attacks
A newly developed encryption framework aims to protect video data from future quantum attacks, all while running on today's conventional hardware.
Halfway through spring football, Notre Dame is putting things together
So far, it’s been a comfortable spring for Notre Dame Football, but will it lead to a productive fall?
Ringling Bros. brings reimagined circus to Cleveland this fall
Ringling Bros. brings a revamped, high-energy circus to Cleveland in October, featuring stunts, acrobats, and interactive pre-show events.
Jay Bilas talks NBA Draft, college basketball, NIL & the evolution of the game
New sports bar to open at former Harpo's site
The bar aims to revive a long-vacant Arapahoe Avenue location.
Reynaldo Lopez and Jorge Soler throw punches in wild Braves-Angels brawl
Carnegie Science cuts 100-year bond with Johns Hopkins
The nonprofit Carnegie Science will close its operations at Baltimore’s Johns Hopkins University this summer, ending a 100-year cooperation between the school and one of the largest private funders of...
Buccaneers' OTAs Kick Off April 20
Buccaneers' offseason workouts begin April 20. Dive into the phased program, from conditioning to team drills, as the Bucs prepare for the season.
Bills want to open new stadium in prime time
‘Long after that debt is paid, we keep sending the bill’
Opinion, comment and editorials of the day
Where to watch New York Knicks vs. Atlanta Hawks: Live stream, start time, TV channel, odds for Monday, April 6
The Knicks and Hawks face off in Atlanta on Monday night.
Foley Entertainment Group, hotels appoint sales, marketing leaders
A number of hotels—as well as Foley Entertainment Group—have appointed sales and marketing leaders in recent weeks. | Hotels and resorts across the country have new sales and marketing leaders.
White House Melts Down for Second Day Over Trump Health Claims
The White House snapped after a post pointed out Trump’s days-long absence from public view.
Houston Rockets vs. Golden State Warriors game preview
Of course Stephen Curry is coming back for this game. Not that it matters, of course. The Houston Rockets have lost multiple games against the Golden State Warriors over the past couple of seasons in which Curry didn’t play. Houston lost earlier this year at Toyota Center. In the one game Curry did play, Reed […]
Chinese Scientists Bioengineering Plants With Firefly Genes to Glow, in Effort to Light Cities at Night
Night lighting may be due for a plant-based glow-up.
Governor Michelle Lujan Grisham
It's back, Albuquerque! The New Mexico Museum of Natural History & Science reopens today, April 4th after eight months of renovations! Expect a revamped lobby, the brand-new Animal Armor traveling...
‘Bob’s Burgers’ Star Eugene Mirman Shares Health Update After Fiery Crash
The governor of New Hampshire and a member of her security detail swung into action at the scene after Mirman became trapped in the burning car.
Mets Morning News for April 4, 2026
Your Saturday morning dose of New York Mets and MLB news, notes, and links.
Kyle Shanahan Drops Hot Take on NFC Contender
Shanahan blasts Rams' Australia game request, demanding league fairness and a Mexico matchup for the 49ers rivalry.
We Asked a Doctor If Omega-3 Supplements Can Support Heart Health
Omega-3 fatty acids are widely known to support heart health, but supplementing with them may not be as effective as getting them from food. Learn whether omega-3 supplements can help boost your heart health.
Stephon Gilmore announces NFL retirement after 13 seasons
The Latest: Trump says Pam Bondi is out as his attorney general
President Donald Trump says Pam Bondi is out as his attorney general.
Cisco Patches 9.8 CVSS IMC and SSM Flaws Allowing Remote System Compromise
Cisco patches two 9.8 CVSS flaws (CVE-2026-20093, CVE-2026-20160), preventing authentication bypass and root access.
Interventional radiology vendor Merit Medical to acquire rival for $140M
The Utah-based company plans to merge with View Point Medical, which manufactures the OneMark Detection Imaging System.
Bill Self announces return to Kansas for 24th season
One of the most renowned coaches in MBB announced that he'll return for his 24th season at the helm of his program for the 2026-27 season.
New Chrome Zero-Day CVE-2026-5281 Under Active Exploitation
Chrome patches 21 flaws including exploited CVE-2026-5281 in Dawn, marking fourth zero-day fixed in 2026, reducing active attack risk.
Serie A winger linked with Liverpool as Salah replacement
Juventus Transfer Plans: Premier League Pressure Mounts as Champions League Stakes RiseChampions League Race Shapes Juventus FutureJuventus stand at a familiar crossroads, one shaped as much by financ...
Arizona baseball drops midweek home game to West Virginia
It’s hard to defend free bases. Arizona pitchers struck out 16 batters and only allowed five hits on Tuesday night, but they also issued 10 walks and hit two batters in a 7-4 loss to West Virginia at Hi Corbett Field. “We gave them pretty much all seven runs,” UA coach Chip Hale said. “They […]
Judge Dismisses Lawsuit That Challenged Ban on Endorsements by Churches
Conservatives had expected a victory in the case after the I.R.S. agreed to a settlement that allowed churches to voice support for candidates.
Under Armour, Kontoor Brands, PENN Entertainment, Deckers, and Carnival Stocks Trade Up, What You Need To Know
A number of stocks jumped in the morning session after investors priced in a potential de-escalation of the conflict in Iran alongside reassuring commentary from the Federal Reserve on interest rates.
Android Developer Verification Rollout Begins Ahead of September Enforcement
Google expands Android developer verification globally after September rollout, adding authentication and delays to sideloading to deter malware.
Thousands Of NYC Restaurants Rely On This 200-Year-Old Business For Their Fish
Given how many restaurants serve seafood in New York City, it's no wonder that this centuries-old marketplace is still running strong.
Most Valuable Promotions signs multi-year deal with Sky Sports
MVP has an official broadcasting partner in the UK.
Trey Hendrickson makes generous donation to The Cincy Hat Foundation
Now a rival on the field, but always a friend off of it.
Military investigating after Kid Rock brags about U.S. Army helicopters flying over his home, will take ‘appropriate action’ if in violation
The military is investigating after Kid Rock bragged about U.S. Army helicopters flying over his Nashville mansion, and say they will take ‘appropriate action’ if in violation.
Heat step up with needed 119-109 victory over 76ers
MIAMI – For those insistent on postseason math, yes, the head-to-head season-series tiebreaker was at stake in this one. But for the Miami Heat this was about more than play-in math. This was about breaking out of a brutal late-season funk that included a road loss a night earlier to the NBA-worst Indiana Pacers. So against the Philadelphia 76ers’ Joel Embiid, Tyrese Maxey and Paul George, the ...
The problem with the NBA's new anti-tanking concepts
Amazon's Spring Sale Brings Big Savings Up to 60% Off SSD and HDD Storage
You can never have too much storage, especially when Amazon has you covered with both internal and external options from Seagate and Sandisk during its annual Spring sale.
Scientists spotted female sperm whales working together during a birth to protect the calf
Scientists have captured rare footage of a sperm whale giving birth, offering a window into the large mammals' behavior.
Scientists spotted female sperm whales working together during a birth to protect the calf
Scientists have captured rare footage of a sperm whale giving birth, offering a window into the large mammals' behavior.
Could newfound leverage change Christian Gonzalez's contract approach?
It's clear why the Patriots should be in a hurry to get a deal done with Christian Gonzalez. But should the top corner show the same urgency?
Former Bears QB made UFL history in Renegades debut
Former Bears quarterback Austin Reed made UFL history in his first game with the Renegades.
Researcher Shows Anxiety Could Be Linked to a Nutritional Deficiency
Research shows that people with anxiety disorders had significantly lower choline levels in their brain tissue.
'Bridal arms' are trending: This simple 3-move Pilates workout sculpts your shoulders, back and biceps
Here's a short routine with only 3 movements to try
The deal with Israel's Rafael: Why is Volkswagen returning to the missile business 81 years after WWII?
Volkswagen, Founded by Hitler and a Producer of Missiles for the Wehrmacht in World War II, Is Set to Have One of Its Plants Manufacture Iron Dome Components for Rafael. After Having Suffered a 44 Percent Drop in Profits Last Year, VW May Be Pivoting Toward the Booming Defense Industry
Bayern Munich officially renews two injured talents
The duo will continue to focus on their recoveries.
Race cars, monster trucks + more sports in Birmingham this weekend
🏎️⚾️ SPORTS IN BHAM: It's a big weekend for you, sports fans! See what to expect.
Instant grades for Patriots free agency signing James Hudson
The Patriots signed the former Giants offensive tackle to a one-year contract in free agency.
Texas A&M softball HC Trisha Ford previews the Texas series
Trisha Ford previews A&M’s trip to No. 1 Texas, stressing growth, lineup clarity, and embracing the rivalry’s trademark “spice.”
Three Dover schools recognized for Science of Reading commitment
Three Dover schools earned the 2026 Governor's Science of Reading Champions award for their literacy instruction.
Why Elite Athletes Train In The Heat & The Science Says You Should Too
The best part? You can do it at home.
Warriors’ dream seeding, matchup scenarios for 2026 NBA Playoffs
The Warriors' season has not gone according to plan at all, but all hope is not yet lost, especially once Stephen Curry returns from injury.
A Church Gym's Murals of Biblical Figures Playing Sports Goes Viral
"Pickleball Paul" and "Air Moses" are ballin' in support of the "real Doctor J."
Treating addiction
Alcohol and drug addiction can cause many harms. This Research in Context feature looks at research into the causes of addiction and new ways to treat it.
USWNT star Lindsey Heaps launches sports show
The show will debut in the "Men In Blazers" network.
World TB Day: Scaling workplace healthcare interventions
Four lessons from the End Workplace TB initiative could help other private sector-led campaign coalitions to scale their workplace healthcare programmes.
Gechter exit sealed? This Bundesliga club is his likely destination
According to a report by 'Sky', Linus Gechter's exit from Hertha is likely a done deal. The 22-year-old Berliner, who is under contract with Hertha until 2028, is reportedly on the verge of moving to ...
French Business Lobby Doesn’t See Inflation Surging on Iran War
France’s largest business lobby, Medef, doesn’t see inflation surging because of the Iran war, the organization’s chief said on Tuesday.
Video: Senate Confirms Markwayne Mullin as Homeland Security Secretary
The Senate confirmed Markwayne Mullin to take over the Homeland Security Department in a 54-to-45 vote on Monday.
Trump’s New Political Tool: ICE
President Trump has increasingly used Immigration and Customs Enforcement to push personal and political objectives, and on Monday sent agents to airports across the country to help deal with long security lines.
From radio to newsreels to Netflix, Yankees chart course through entertainment history
For more than a century, the Yankees have been more than a baseball team. The sport’s most storied franchise is a pop culture touchstone, a versatile backdrop that serves as both a symbol of excellence and a punchline across television, movies and more. So as the Yankees prepare to break
Republicans fear this Democrat in Georgia Senate race: ‘This guy’s no slouch’
The Cook Political Report rates the general election as a toss-up.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Phillies sign pitcher Cristopher Sánchez to 6-year, $107 million contract extension
Gen Z really, really loves China's trains
This is a condensed version of Business Insider Today, a newsletter that gives you a look at the week’s top stories. Sign up here to get the full Business Insider Today in your inbox every day for the top stories in markets, tech, and business.
Businesses worried as fuel prices rise
An increase in fuel prices amidst the US-Israel war with Iran is affecting businesses in the UK.
Beshear Criticizes Vance in Ohio, Stoking 2028 Presidential Tensions
Mr. Beshear, the Democratic governor of Kentucky, sharply criticized Mr. Vance as both angle for potential presidential runs.
Full circle: Sean McVay collecting former players on coaching staff
Robert Woods joins Brian Allen on Sean McVay’s Rams coaching staff
Apple to Launch More New Hardware This April
Apple isn't done yet. After announcing seven new products in March – including the iPhone 17e, iPad Air, MacBook Air, MacBook Pro, MacBook Neo, Studio Display, and Studio Display XDR – the company has one more launch on the books in the coming weeks (as far as we know, at least). AirPods Max 2 go up for pre-order on March 25, with availability beginning in early April.
HSBC mulls job cuts that could impact around 20,000 roles, Bloomberg News reports
HSBC Holdings Plc is weighing a wave of deep job cuts over the coming years that could ultimately impact around 20,000 roles, or about 10% of its total workforce, Bloomberg News reported on Wednesday, citing people familiar with the matter.
How a ‘locked in’ offseason prepared Spurs for championship push
In clinching the Spurs first 50-win season in almost a decade, Victor Wembanyama pointed back to before the season started.
March Madness: West region predictions, Cinderella, expert picks, schedule, odds, betting lines and more
Love retro video games? Here are our favourite consoles to play on
From Evercade and Atari to Nintendo and Playstation.
Opinion | The Unlikely Alliance to Save East Palestine Ohio
In Ohio after a toxic chemical accident, finding common ground in the country’s health wars.
The Promptory Launches First Curated AI Marketplace with Built-In AI Strategy Director for Small Business and Enterprises
FRISCO, Texas, March 17, 2026--The Promptory, a privately held technology company, today announced the official launch of its AI tools marketplace — the first curated platform built specifically to help small, medium, and enterprise businesses find, evaluate, and implement the right AI tools for their specific needs.
Everything Coming in Starfield’s Free Lanes Update & Terran Armada DLC
April 7 marks the beginning of a new era for Starfield, with the game’s biggest free update yet, the all-new Terran Armada story DLC, and the official PlayStation 5 launch all arriving at once.
Deadline Hollywood
Debra OConnell, Chairman of Disney Entertainment Television, has unveiled her direct reports, including Craig Erwich, who adds 20th TV Oversight. Read more below.
Deadline Hollywood
CBS and Entertainment Tonight are saying goodbye to The Neighborhood with a farewell special. Read more below.
Apple Acquires Final Cut Pro Plugin Company MotionVFX
Apple today acquired the major Final Cut Pro plugin company MotionVFX. MotionVFX is a Polish company founded by Szymon Masiak in 2009. It creates high-quality plugins, transitions, templates, and visual effects (VFX) for video editors. The company specializes in tools for Final Cut Pro, DaVinci Resolve, and Apple Motion, such as mFilmLook, mO2, and the Design Studio extension.