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Analysis | The midterm battle for power in the states
Republicans are on defense in governor and state legislative races.
Thune presses Trump for more funding toward battleground races red
Senate Majority Leader John Thune (R-SD) on Monday revealed he is pressing President Donald Trump for more funding toward battleground races in the midterm elections, as Republicans fight to stave off losses in November. Thune said that he’s been emphasizing the question of resources for candidates during conversations with Trump and the president’s advisers, in […]
South Texas races could determine control of Congress
The nonpartisan Cook Political Report recently moved Texas’ Congressional District 15 from “Lean Republican” to “Toss-up.”
Researchers find nearly $80 million in AI political ads, most don’t disclose AI
AI is reshaping political advertising landscape ahead of the midterms, but most campaigns aren’t disclosing AI use, making it harder for voters to do a fair assessment.
Forbes names science center as top 250 healthcare employer in new ranking
Forbes ranked the UT Health Science Center at San Antonio in the top 250 healthcare employers for 2026 alongside two other hospital systems in San Antonio. University Health was ranked at 128, Baptist Health System at 199 and the UT Texas Health Science Center at San Antonio at 240. This list determines which hospital systems...
Most Americans support switch to Medicare for all health insurance
NEW YORK >> Most Americans now favor government-paid health insurance for all, according to a new poll, as voters across party lines see major healthcare reforms as a priority less than a month before midterm elections to decide control of Congress.
Will Democrats’ midterm wave reach California’s Central Valley? Bernie Sanders rallies the vote
Many Democrats are hopeful that Randy Villegas, their congressional candidate in the traditionally conservative Central Valley, can prove that progressive ideas, like universal healthcare, are palatable outside of safe blue cities.
Rating the Governor Races: The States Where Democrats Are Poised for Victory
Election Day this year will determine who holds the keys to influential executive mansions across the country. Thirty-six states have gubernatorial contests on the ballot, and the results in November will determine whether Democrats control a majority of the nation’s governorships for the first ...
ODNR Invites Ohioans to Celebrate Earth Science Week 2026
Article presented by Litter Quality Propane and Hometown Motors, Inc … COLUMBUS, Ohio – The Ohio Department of Natural Resources (ODNR) Division of Geological Survey is celebrating Earth Science Week from Sunday, October 11, through Saturday, October 17. Four special events will be offered throughout Ohio and will coincide with the annual national celebration. “We […]
Wizards Deliver Bad News For Anthony Davis Future
The Washington Wizards could soon bid goodbye to Anthony Davis, their newest star center, whom they got via trade with the Dallas Mavericks last season. According to The Athletic’s David Aldridge and Josh Robbins, the Wizards are not keen on offering Davis a four-year, $275 million maximum contract extension. That means Davis’ long-term future in […] The post Wizards Deliver Bad News For Anthony Davis Future appeared first on HEAVY.
Rating the Governor Races: The States Where the GOP Is Poised for Victory
Election Day this year will determine who holds the keys to influential executive mansions across the country. Thirty-six states have gubernatorial contests on the ballot, and the results in November will determine whether Democrats control a majority of the nation’s governorships for the first ...
Americas advance on healthy aging, but gaps remain as 2030 approaches
Washington, D.C., 6 October 2026 (PAHO) – Countries in the Americas have made progress in policies, health services and monitoring to support healthy aging, but gaps in financing, implementation and long-term care remain, according to regional findings from the 2026 midterm review of the United Nations Decade of Healthy Aging (2021–2030).
DOL renews charter for OSHA advisory committee
Eight of the 12-member committee’s seats are vacant, and the terms of the remaining four members are set to expire in January.
Tom Tiffany, David Crowley making final push as Election Day nears
In less than one month, voters will head to the poll to determine the direction of Wisconsin for the rest of the decade.
Midterm Election Update: Vaccines
Federal vaccine policy has shifted toward fewer recommended routine childhood vaccinations, more emphasis on individual decision-making, and greater skepticism about the safety and efficacy of some vaccines. The changes coincide with declining childhood vaccination rates, rising exemptions from school vaccine requirements, and a major measles resurgence.
Susan Collins, a political survivor, tries to outrun Trump
In her bid for a sixth term representing Maine, Susan Collins has been beset by President Donald Trump weighing her down with constant controversy.
From Building Homes to Building Hope: Larry and Heidi Canraelli Commit $50 Million to Intermountain Health Nevada Children’s Hospital
LAS VEGAS — Intermountain Healthcare Foundation today announced a remarkable $50 million commitment from Larry and Heidi Canarelli to help bring Nevada's first comprehensive, stand-alone children's hospital closer to reality. This gift advances Intermountain Health's Nevada Campaign for Kids, expanding access to specialized pediatric care clos...
Broncos Get Encouraging Riley Moss Injury Update
Broncos cornerback Riley Moss reportedly avoided a fractured rib, and his injury isn't considered long term after he left Sunday's loss to the 49ers.
Colonial Group completes Foster Fuels purchase
Georgia-based Colonial Group has completed its acquisition of Foster Fuels, the Brookneal-based fuel distributor, for undisclosed terms.
Want To Know If Someone Likes You? Science Suggests A Key Vocal Feature Can Reveal Who We Like, And Influence Who Likes Us
Interestingly, in works differently for long- and short-term relationships.
Biological aging offers clues to long-term health after Fontan surgery
Our birthdays tell us how long we have lived, but not necessarily how our bodies are aging. Biological age reflects the condition and function of our cells and tissues, shaped by genetics, lifestyle, ...
Brazil: Lessons from a Disaster
By Antonio Martins (Outras Palavras) Defeats become deeper and more prolonged when we misunderstand what caused them, avoid correcting course, and embrace “solutions” that only compound our mistakes. Lula’s government and the Brazilian left suffered a disaster in Sunday’s election. Contrary to every poll, the president finished the first round 2.2 million votes behind Flávio Bolsonaro—and, more significantly, 3.4 million votes below his total four years ago, when the machinery of the state was working against him and in favor of his opponent. His vote share declined in 98 percent of Brazil’s municipalities. The PL, the main party of the far right, elected 121 deputies and 28 senators, becoming the largest caucus in both houses of Congress. The parties aligned with the Centrão—Brazil’s bloc of transactional center-right parties—were somewhat diminished, but will still hold roughly 250 seats in the Chamber of Deputies and 35 in the Senate. That will make it easier to assemble the majorities needed to amend the Constitution or impeach Supreme Federal Court justices. If elected, Flávio Bolsonaro could appoint four members of the Court, substantially altering its internal balance of power. What produced these results? How can the far right be prevented from consolidating them into a prolonged political hegemony? And what is the essential change of direction the left now needs? Explaining the Disaster Across the commercial media and the exuberant chaos of digital platforms, interpretations are multiplying. Some focus on specific episodes: Lula’s absence from the Globo debate, his very close relationship with Alexandre de Moraes, or his emphasis on issues supposedly remote from most people’s everyday concerns, such as rare earth minerals. Among the more systemic interpretations, three seem especially questionable. One argues that the principal defeat was not the left’s, since its congressional representation declined only slightly. The decisive movement captured at the ballot box, according to this view, was a shift within the right itself—from the more moderate and transactional forces of the Centrão toward the more ideological and radicalized forces of the PL and Novo. A second interpretation holds that the nature of electoral and political processes has changed. The material interests and aspirations of society, it argues, no longer play the central role they once did; they have given way to forms of subjective self-identification that the left has yet to understand. And a third concludes that, because of these two developments, we should expect a political winter: a prolonged period in which the far right and the broader right dominate Brazilian political life. There are important elements in all three interpretations. The problem lies in what they deny or leave out: Lula’s third government was a small-bore government. It offered the majorities that elected it neither a clearly better life nor reasons to believe again in politics and its power to transform society. These failures flowed from two fatal accommodations, which I will examine below. As a result, the government suffered a slow but steady erosion of support. And, as has happened in so many Western countries, it gave the far right the opportunity to present itself as anti-system and to benefit from popular frustration and distress. The interpretation that emphasizes the migration of votes from the center-right and traditional right toward the far right has been advanced, among others, by the courageous journalist Leonardo Sakamoto. In his UOL column on Monday, October 5, he highlights the miserable behavior of the traditional conservative parties. Over the past four years, they repeatedly joined forces with the “neo”-fascists, helping to “normalize” them—a criticism that could equally be directed at almost the entire corporate media. Believing they could use the far right as a stepping stone, they instead ended up partly devoured by it. This was especially true in the Senate, where the PL’s gain of 13 senators and Novo’s gain of two came at the expense of the PSD, which lost nine; the MDB, which lost two; the PSDB, which lost two; and the PP, which lost one. Sakamoto’s observation is accurate and necessary, but it leaves uncomfortable questions unanswered. Why did the erosion of the Centrão benefit the far right rather than, for example, producing growth for the left—as has happened so many times before, both in Brazil and elsewhere? The answer is not difficult. Throughout its four years in office, Lula’s third government was almost invariably associated with the Centrão. Here lies its first accommodation: accepting the limits imposed by conservative institutions; avoiding, as much as possible, any attempt to strain those limits through popular pressure; and believing only in the modest changes that could be squeezed through openings in Congress. The failure of the campaign to end the six-day workweek is emblematic. Lula could have electrified the presidential race by pairing it with a popular campaign for passage of the measure. Instead, he chose to place his hopes in the hands of Senate president Rodrigo Alcolumbre. He generated no mass mobilization, did not force his opponents onto an uncomfortable defensive, and won no victory. In September 2025, the government squandered the greatest of its many opportunities to shake up conservative power in Congress. Popular opposition to the so-called Shielding Amendment—which, if approved, would have restricted criminal proceedings against members of Congress—brought crowds into the streets, mobilized primarily by artists and social movements. This opened the possibility for a broader political education: a campaign that could begin exposing the limits and dysfunctions of Brazil’s political system while putting Bolsonaro’s movement on the defensive for its predictable support of political privilege. The amendment was defeated. But the executive branch then backed away from the fight. It remained associated with an institutional world widely seen as corrupt, elitist, and indifferent to ordinary people’s struggles. In doing so, it forfeited its credibility as a vehicle for the protest vote. On Sunday, it reaped the bitter fruits. Are We Doomed? Taking a different approach from Sakamoto, the philosopher Moysés Pinto Neto and other writers have drawn attention, in their first analyses of October 4, to the fragmentation of the public sphere produced by Big Tech platforms. Through their algorithms, these platforms present each person with a different view of social reality. As a consequence, it becomes much harder to identify common material problems and demands—for example, the fight for labor rights or for a properly funded public health system. Voters no longer embrace such demands, these authors argue, because they no longer see themselves as part of a collective. Instead, they tend to value the identities assigned to them by neoliberal subjectivity—the role of the entrepreneur, for example. On this interpretation, the left’s possible error lies in clinging to outdated illusions. Moysés’s warning is highly relevant and resonates with arguments such as Naomi Klein and Astra Taylor’s “Apocalyptic Fascism and the Billionaires’ Bet.” Unlike a century ago, the far right no longer promises a radiant future. It concentrates instead on resentment—especially that of young men. “They belong to a generation that fears it may never own a home, but compensates with the pleasure it gets from constantly provoking progressives online. Convinced their future has been stolen, they share memes romanticizing historical authoritarian regimes,” the authors write. But Moysés seems to confuse this danger with inevitability. He fails to see that the left’s answer cannot be adaptation. On the contrary, it must strengthen the possibility of politics as collective action. Nor does he recognize that precisely such a reversal is already becoming possible in some of the most promising mobilizations of the twenty-first century: the election, at the end of 2025, of the young Muslim Zohran Mamdani as mayor of New York, on a platform centered on the intensely material fight for an affordable city; the Left Party’s victory in Berlin two weeks ago, built around the demand to expropriate private real-estate corporations; and the very recent wave of demonstrations in Spain—including an occupation of Madrid’s Puerta del Sol—in which tens of thousands of young people mobilized by the Tenants’ Union have demanded limits on rents. By putting itself in the straitjacket of the “fiscal framework” in the first months of 2022, Lula’s third government adopted the second fatal accommodation of its term. Faced with conservative institutions and a country devastated by four years of Bolsonaro, increased public investment was the government’s remaining weapon for offering a more dignified life to the majority and forging an anti-conservative pact with them. The same state that disburses 1 trillion reais a year to enrich a small class of rentiers could instead spend money to extend the Family Health Strategy to every Brazilian, at a cost of 30 billion reais; provide full-day public schooling and childcare to all adolescents and children—and, especially, relief to their mothers; achieve universal sanitation while cleaning up polluted urban rivers; multiply metro systems; begin transforming the urban peripheries; and undertake many other urgently needed projects. In April 2023, an article in Outras Palavras warned that the fiscal framework could “shrink the Lula government and preserve the forces that condemn the country to inequality and regression.” A year later, another article showed that restraints on public spending were strangling policies vital to ordinary people and undermining the president’s popularity. In November 2024 came a reality check, in the form of the government’s humiliating defeat in the municipal elections. Even then, the fiscal lock was neither removed nor loosened. On the contrary: throughout the government’s four years, fiscal restraint remained central to its political narrative. The administration proudly proclaimed that it had “put the state’s accounts in order,” without grasping either how misleading that phrase was—given the payment of 1 trillion reais in interest—or how badly the message was hurting it politically. Lula finally woke up in September 2026. The increase in Bolsa Família benefits, after four years of being frozen; the announcement that anti-obesity drugs would be offered through Brazil’s public health system; and the ban on online betting showed that the state has the power to act decisively on behalf of the majority when those in government are willing to confront obstacles. The huge marches that closed the campaign in Fortaleza, Salvador, Rio de Janeiro, and São Paulo on the eve of October 4 showed how such initiatives can mobilize activists and the broader public. But it was too late—and too little to change the outcome of the first round. History has not ended The possibility of a turnaround in the three weeks leading up to November 25 cannot be ruled out. It will not be simple or easy. Lula must not only make up a deficit of 2.2 million votes; he must also offset the movement of voters who backed other right-wing candidates in the first round, most of whom are likely to move toward Flávio Bolsonaro. Pulling that off will require a broad, grassroots effort to win over voters, potentially reinforced by new initiatives from Lula. The coming hours and days will be decisive. If Bolsonaro’s movement also wins the presidency, the result will create a high-risk situation for Brazilian sovereignty and democracy. The enormous challenges posed by such an outcome would require the left to reexamine, in depth and with a genuine willingness to engage in self-criticism, its political projects—or its lack of them—and its practices. But would that mean we are condemned to the long winter of far-right hegemony that some analyses are beginning to forecast? It is far too early to say, suggests a recent text by Álvaro García Linera, the thinker who served as vice president of Bolivia under Evo Morales. His central hypothesis is that this political current will prove short-lived. At a moment when the entire world is once again talking about sovereignty and protecting national economies, the far right offers a stale, recolonizing neoliberalism. Its submission to the United States is as blatant and pathetic as Flávio and Eduardo Bolsonaro’s overtures to Donald Trump. Its project amounts to something like every man for himself: greater inequality, capitalism without limits, devastation, and supremacism. Will it work? In the United States, just two years into his second term, Trump himself is reaching record levels of unpopularity and may be on the verge of losing Republican control of both the House and Senate in November. Every new beginning is difficult. Whatever the outcome of the second round, the defeats of October 4 show how profoundly the Brazilian left will have to rethink and rebuild. But just as it would be foolish to underestimate the seriousness of its mistakes, it would be equally foolish to conclude that rebuilding a political project is no longer possible. History has not ended. The times are moving faster than ever. Originally published in Portuguese by Outras Palavras. English translation by Eric Blanc; I’ve added the subtitles. More We can’t stop the far right at home or abroad without a revitalized labor movement, which is yet another reason why you should become a sustaining supporter of the Emergency Workplace Organizing Committee (EWOC) — one of US labor’s pivotal bright spots. Relatedly, Jacobin published a short piece of mine reflecting on a decade of Bernie Sanders inspiring a whole new generation of young worker organizers.
Red Wings Reverse Course in Simon Edvinsson Contract Talks
The Detroit Red Wings have changed course in Simon Edvinsson contract talks, with Elliotte Friedman reporting longer-term offers are now on the table.
Jannik Sinner Ends 2026 Season Early With Knee Injury
In a somber video message posted on social media Tuesday, world No. 1 Jannik Sinner announced that his 2026 tennis season is officially over as he prioritizes long-term recovery from a lingering right knee issue. The 25-year-old Italian, speaking directly to fans, said: “Hello everyone, I would like to give you a little update. Me together with …
StoneX maintains Buy rating on Sphere Entertainment, $125 price target
StoneX maintained their Buy rating on Sphere Entertainment's stock with a price target of $125.00.The price target implies an upside of 12.8% from the Oct 5 close of $110.80.Key takeaways from the analyst noteLong-Term Growth Potential: Despite recent challenges, Sphere Entertainment is expected to…
NAACP launches voter protection hub for midterm elections
The civil rights organization is stepping up efforts in response to President Donald Trump’s push to change voting rules.
Chris Olave Injury Update: Saints WR’s Status Revealed
Chris Olave left the Saints Week 4 loss late after taking a shot to the knees, but it appears as though the wide receiver will be ok and dodged a long-term injury. Originally selected in the first round of the 2022 NFL Draft, the Ohio State product quickly established himself as the team's go-to option …
Trump, politics and lawfare take center stage in Arizona's attorney general race
Four years ago, Democratic Attorney General Kris Mayes won the office by less than 300 votes. Now, she’s hoping her track record taking on President Trump, fake electors and predatory businesses will earn her a second term in office.
Iowa's 3rd Congressional District candidates sound off on economy, war
Republican U.S. Rep. Zach Nunn faces a challenge from Democrat Sarah Trone Garriott in the Nov. 3 midterm election. Meet the candidates.
Samuel Alito's gift to Democrats
The justice's refusal to retire deprives Donald Trump of a Supreme Court vacancy ahead of likely blue midterm wave
Trump wants to rewrite the midterm lexicon
Changing the words may not change the politics.
AMC Entertainment Refinances With $2.0B Notes, $850M 1L, $1.12B 2L; Retires Prior Debt
AMC Entertainment Holdings executed a broad refinancing that includes $2.0 billion of 8.875% first lien notes due 2031, an $850 million first lien term loan maturing 2031, and a $1.12 billion second lien term loan due 2033. Proceeds were used to repay and terminate certain existing facilities and t…
Ohio Early Voting Begins With US Congress Control on the Line
By Richard Cowan MEDINA, OHIO, Oct 6 (Reuters) - Early voting begins on Tuesday in Ohio, where the winners of November's midterm elections will help determine whether Republicans or Democrats control the US Congress for the next two years, given the state has one Senate seat and two House seats ...
Exclusive | Apple News hid stories about how broke the DNC is ahead of the midterms, watchdog alleges
Cramming for exams? Five science-backed ways to study better
Rereading and highlighting aren't enough for long-term learning. Experts share science-backed strategies to help students study smarter.
BTIG maintains Buy rating on Sphere Entertainment, $160 price target
BTIG maintained their Buy rating on Sphere Entertainment's stock with a price target of $160.00.The price target implies an upside of 44.4% from the Oct 5 close of $110.80.Key takeaways from the analyst notePositive Long-Term Growth Potential: Sphere Entertainment is positioned uniquely in the grow…
Most Americans support switch to Medicare for all health insurance
Most Americans now favor government-paid health insurance for all, according to a new poll, as voters across party lines see major healthcare reforms as a priority less than a month before midterm elections to decide control of the US Congress.
Democrats could win majority of governor’s offices for first time in 16 years
As the political prospects for Republicans worsen ahead of November’s midterm elections, the GOP is increasingly playing defense over its yearslong grip on state governments. That’s particularly true for gubernatorial elections, as Democrats could win a majority of governorships for the first time since 2010. Currently, Republicans boast a 26-24 gubernatorial advantage over Democrats. This […]
The Senate is up for grabs. Plot each party’s best path to winning
As many as 10 key Senate races identified by CNN that are on the ballot in November will likely determine which political party controls the chamber.
Local political polarization is rising sharply ahead of the midterms, survey finds
Cost-of-living issues are driving up tensions in local communities, while immigration is the most polarizing issue nationally, local government officials said in a new survey.
KFF Health Tracking Poll: Health Care Issues in the Lead-Up to the 2026 Midterm Election
With the 2026 midterms about a month away, health care costs remain tied with gas as voters’ top midterm concerns and the Democrats hold a clear edge over the Republicans Party on who voters trust to handle many top electoral issues, including the cost of health care and the cost of living. Two-thirds of U.S. adults now favor Medicare-for-all, a new high in KFF Polling, but support shifts when competing claims from critics and proponents are heard.
Poll: Cost of Health Care and Gas Top Voters' Midterm Concerns; Democrats Hold Significant Advantage on Health Care Costs and Cost of Living
Just a month away from the midterm elections, affordability worries continue to top the public’s list of midterm election issues, with health care costs and gas costs tying as the top economic concern, KFF’s new Health Tracking Poll finds. Voters overall trust Democrats more than Republicans to handle the cost of health care and the cost of living.
Democrats are taking big chunks of GOP voters in key Senate races, polls show
President Donald Trump has never had worse poll numbers with his base than he does ahead of the 2026 midterm elections.
Political experts talk midterm issues, expectations at Catawba panel
SALISBURY — The midterm elections loom in the not-too-distant future, and questions on U.S. electoral systems are as pervasive as ever. The “What’s at Stake” panel at the Catawba College […]
Long-term "Food Is Medicine" program improves cardiometabolic health in adults
Providing people with nutritious foods can improve the management of chronic metabolic diseases such as type 2 diabetes and hypertension.
SCOTUS order could send WA political maps back to the drawing board
It won't happen before the 2026 midterm elections. But Monday's development is the latest twist in the saga of Washington's redistricting efforts.
Trump takes midterms message to deep red Nebraska
President Donald Trump gave supporters a campaign-style speech in Nebraska in a continued effort to fire up the GOP base ahead of the midterms. CNN’s Jeff Zeleny reports.
A simple guide to the US midterms
US voters will head to the polls on 3 November in a ballot that could have a major impact on Donald Trump’s presidency.
Retiring GOP Senator reveals his ‘WTF’ moments during the second Trump term
Trump uses anti-transgender slur to attack South Carolina Senate candidate
President Donald Trump on Monday used an anti-transgender slur to attack Democratic South Carolina Senate candidate Dr. Annie Andrews, as he tries to push his hand-picked GOP candidate, Sen. Darline Graham, over the finish line in the midterm election.
Robert De Niro rips 'coward' Trump over voter suppression
Robert De Niro is ramping up his criticism of the Trump administration in the final weeks before the 2026 midterm elections.
Top Line MN Wild Center Leaves Practice with Injury
The Minnesota Wild have another injury concern after Russian centerman Danila Yurov left Monday's practice early with a previously undisclosed injury.
US says foreign financial institutions doing business with Iran may be sanctioned without notice
WASHINGTON, Oct 5 (Reuters) - The US Treasury Department said on Monday it was alerting foreign financial institutions that continue to do business with Iran or its financial sector that they may be sanctioned by Washington without advance notice. DETAILS: • "Foreign financial institutions continuing to transact with sanctioned Iranian financial institutions could be targeted at any time without advance notification and should take immediate action to terminate such activity and relationship
Arlington maritime startup raises $140M in Series B funding
Arlington County maritime startup Quartermaster AI raised $140 million in Series B funding to grow headcount and recruit new vessels.
Trump’s midterm messaging undercuts GOP candidates
Many Republican candidates have found themselves in surprisingly competitive races
Trump’s midterm messaging undercuts GOP candidates
Many Republican candidates have found themselves in surprisingly competitive races
Mail mystery: Astoria businesses, City Hall report spotty delivery, missing packages
Inconsistent mail delivery in Astoria has attracted the attention of Oregon's U.S. senators, especially as midterm elections near.
Darko Rajakovic Reveals What’s Behind Kawhi Leonard’s Delayed Raptors Return
Toronto prioritizes long-term health over preseason minutes as the superstar ramps up his reconditioning process.
Why I Don’t Think Ride Or Die Should Have Been Cancelled (And What Company Should Save It...)
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) So…I recently came across a Reddit thread, talking about films on streaming, wondering why there are no reliable sources out there for streaming ratings data. Sigh. Honestly, as annoyed as I am that so many still don’t realize that we have streaming ratings, I somewhat get it. Until now, there was such a long delay between when a show or film came to streaming and when we got its viewership data; I understand why people were confused. (But, as you know, this just changed.) Also, even back in the day, how many people knew how well films did on television? Luckily, as a reader, you’re in the know. Okay, on to this week’s issue. I want to take a look at Prime Video cancelling Ride or Die and whether I agree with that decision. Overall, we didn’t have any breakout hits (no TV shows landed over 20 million hours according to Nielsen) but we have a lot of steady performers on the streaming charts. Plus, we’ll look at where $50 million in missing box office dollars went. (Spoiler: straight-to-streaming.) All that, plus new episodes of The Secret Lives of Mormon Wives, Supergirl heads to streaming, a new YA show does well on Netflix, the viewership for the Daily Wire’s $50 million fantasy show, what TV show hit-maker can’t make streaming hits, CD sales, all the flops, bombs and misses, and a whole lot more. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of September 7th to September 13th, 2026. You can find a link to my terminology here.) Subscribe Television - Ride or Die Is a Hit…But It Got Cancelled? What The Data “Says” I hate the phrase “here’s what the data says”, even though sometimes I find myself using it. If data just told us everything, we data folks would be out of a job! Data is often messy, complicated and nuanced. When it comes to strategy, many of the best decisions can’t actually use “data”, since it’s vastly too complicated to model. Anyways, I’ve been singing the praises of Prime Video’s Ride Or Die this summer, a show that did very well for them. And yet…it got cancelled. Now, usually when a show gets cancelled, a bunch of websites say “a hit show got cancelled”... Here’s the thing, though: in this case, they’re right! The data “says” that this show was a hit. Specifically, out of 522 first seasons to make a week on the Nielsen charts since 2020, it’s the 75th biggest. On Amazon, Ride or Die is eighth out of 41 first seasons: That’s top 15th percentile all time, almost exactly, which is my definition of a “hit”! I mean, outside of Reacher, Amazon needed a hit this summer! (Admittedly, Off Campus did well for Amazon in the spring, but Ride or Die performed even better.) So what happened? Why did Amazon cancel one of their rare 2026 bright spots? Well, Deadline reported a reason—which I’ll get to—but I’d break it down into three relevant questions: What is a given streamer’s reasoning? Is that reasoning sound? Could the stated reason not be the real reason? According to Deadline, Amazon felt the show “over-indexed” in middle-aged women. (This was based on leaks from within Amazon.) The logic is this: Amazon already reaches this demographic because of unlimited two-day shipping bundled with Prime, so they don’t really need more shows like this. Now, it’s my job to ask if that’s a good reason, and I’ll be honest, in this case, I don’t think it is. Sure, this show may “over-index” in middle-aged women—I’ll just assume that’s the case here—but I think folks often oversell how important over-indexing actually is. When a show is a “hit”, it isn’t a bit bigger than its rivals; it’s usually multiples bigger. For example, Elle only made the charts for two weeks at 8.3 million hours each. So Ride or Die was 80% bigger in its first two weeks, and likely had a much stronger hold, with its terrific 13 million hours in week three. Ride or Die was nearly three times bigger than Sterling Point through three weeks too. And that means that _Elle, Sterling Point a_nd other Amazon YA shows need to not just over-index a little with younger women (assuming that’s who Amazon prefers over middle-aged women), but massively over-index. Otherwise, more people in that demo (and a bunch more besides) likely watched Ride or Die. (I’ll try to explore this concept more in a future article.) And don’t get me started on how Ride or Die did compared to a certain (very, very popular, possibly the world’s most popular) YouTuber’s reality show…which didn’t make the charts after its first week and likely cost much, much more than Ride or Die. All to say, Amazon-MGM Studios/Prime Video can tell reporters that this show didn’t reach the right audience, but that excuse feels weak to me. So this leads to the third question: could other reasons have come into play? Yes! Renewal or cancellation decisions rarely (I’m tempted to say “never”) boil down to one variable. At its simplest, it’s two things: budget versus viewership. But often factors like critical acclaim, ownership and, yes, personal opinion come into play. In this case, Amazon has a new executive running things, and this show isn’t owned by Amazon-MGM Studios (unlike Elle). And yes, it may not have indexed with the right target viewers, too. Likely all of those factors came into play.1 My guess is ownership ended up mattering most. Amazon doesn’t own Ride or Die. It’s actually produced by another major studio. Fortunately/allegedly, this show is being shopped around. I can think of one brand new CEO who should consider it for one of his two major streamers…especially if he wants to rebuild goodwill in Hollywood. His name is on this list of exec producers of Ride or Die… If David Ellison needs some goodwill—and he does—rescue this female-led show tomorrow and grab some good headlines for a day. The data justifies it. Quick Notes on TV We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… How The Secret Lives of Mormon Wives latest season did on Hulu, post-controversy... Whether Supergirl soared on HBO Max... Why the box office is losing money due to the streamers... The viewership for the Daily Wire’s $50 million fantasy show... Updates on The Gentlemen, Lanterns, Outer Banks, King of the Hill and more... What former hit-maker has three streaming flops in a row... Whether The Mandalorian and Grogu popped in week two... All the flops, bombs and misses... And a whole lot more... ...please subscribe! We can only keep doing this great work with your support. If you want an idea of just how much content you’d get in a full issue, check out this older issue. Coming Soon! Oh man, we’re almost caught up! We just have two more issues, then the streaming Ratings Report will be coming out just two weeks after a TV show premieres! Next issue, I’ll be looking at the first two weeks of the NFL Thursday night games on streaming, a huge new spinoff, Reacher’s Neagly on Prime Video, and the latest edition of Monster: The Lizzie Borden Story on Netflix, the return of Slow Horses on Apple and MobLand (quietly one of their biggest shows) on Paramount+, and Dancing with the Stars on both ABC and Disney+. Plus I’ll take a look at animation for adults in 2026. The week after, a ton of movies are coming to streaming: Toy Story 5 on Disney+, Backrooms on HBO Max, Jackass: Best and Last on Paramount+ and The Breadwinner on Netflix, plus a Unabomber film on Netflix and a romcom on Prime Video. Woody Harrelson and Matthew McConaughey have a show on Apple, along with a game show inspired by Willy Wonka that everyone seems to hate. Long term, some crazy (but hopefully crazy like a fox) IP news. FX ordered a new Sons of Anarchy show from Charlie Hunnam, but it’s not about the biker gang. No, it features the show’s cast playing themselves in a new “meta-thriller”. Huh. And a lot of the cast is coming back. Next, Ryan Gosling is producing a Flintstones movie about a “grown-up Bamm-Bamm Rubble”. Also, huh. This one is in “early development” so we’ll see what happens. Both projects are based on IP, but also seem to have crazy takes on the IP, which I like.
Sen. Tillis says his vote for Hegseth was 'biggest regret of my career' in new book
Republican Sen. Thom Tillis says in a new book that his deciding vote to confirm Defense Secretary Pete Hegseth in January 2025 is the “biggest regret of my career” and that he also “should’ve stopped” Robert F. Kennedy Jr. from becoming Health and Human Services secretary in the early days of President Donald Trump’s second term.
Democrats release midterms ad featuring family of Epstein victim Virginia Giuffre
(CNN) — The campaign arm working to elect House Democrats released a political advertisement on Monday featuring the family of Virginia Giuffre, who was the first victim of Jeffrey Epstein
Bladen Community College to host “So You Want to Start a Small Business” class and preview Pitch It Bladen 2027
The Small Business Center at Bladen Community College invites aspiring entrepreneurs to attend “So You Want to Start a Small Business” on Tuesday, Oct. 13, 2026, from 6:00 p.m. to 8:00 p.m. in Building 14, Room 104. This class will help participants explore what it takes to become an entrepreneur and take the first steps toward turning a business idea into reality.Participants will explore the entrepreneurial mindset and consider whether they have the interests, characteristics, motivation and willingness to take on the challenges of business ownership. The class will encourage attendees to examine their personal goals, expectations, strengths and readiness to pursue entrepreneurship.Attendees will also gain insight into the realities of starting and operating a small business, including the commitment, planning, decision-making and perseverance required to build a successful venture. Whether participants are just beginning to consider business ownership or already have an idea they want to pursue, this class will provide a foundation for determining their next steps.In addition to the class instruction, attendees will receive advance information about the upcoming Pitch It Bladen 2027 Business Competition, including the application form and details about the program. Individuals who are ready to move forward may submit their applications early and have the opportunity to receive advance acceptance into the program.Pitch It Bladen helps aspiring and emerging entrepreneurs develop their business ideas through structured instruction in business planning, financial management, cash-flow projections, marketing and operations. Participants work toward completing a business plan and preparing a business pitch, with the opportunity to compete for cash prizes.Last year's Pitch It Bladen program demonstrated the value of investing in local entrepreneurs by helping participants strengthen their business knowledge, develop their business plans and prepare to present their ideas. The competition showcased the creativity and potential of Bladen County's small-business community and provided participants with practical tools to move their business goals forward.Building on that success, Pitch It Bladen 2027 will provide another opportunity for local entrepreneurs to gain knowledge, build confidence and take meaningful steps toward launching or growing a business.“The Small Business Center wants to help individuals make informed decisions about entrepreneurship before they take the leap into business ownership,” said Theresa Dennison, Small Business Center director, in a press release. “This class gives participants an opportunity to evaluate whether entrepreneurship is right for them while also introducing them to Pitch It Bladen 2027 and the resources available to help them succeed.”Registration: Visit www.ncsbc.net and search for the class by name, or contact the Small Business Center at 910-879-5572 for additional information.
Will R.I. voters, elected officials continue investing in life sciences?
Rhode Island starts in a strong position and has the ingredients needed for innovation and growth. What we don’t have yet is a long-term commitment, writes the CEO of the RI Life Science Hub.
Supreme Court kicks off new term with major climate case
The Supreme Court returns for its new term on Monday, and oral arguments in a major case over the fate of a costly climate change lawsuit brought by Boulder County, Colorado, will kick off a term set to feature several blockbuster legal battles. Suncor Energy v. County Commissioners of Boulder County will decide whether a […]
Fox Tells DC Circ. Worker Wasn't Fired Over Leave, Politics
Fox News urged the D.C. Circuit to reject a former Capitol Hill producer's bid to revive claims that he was fired over his political views and use of sick leave, arguing he was terminated instead for insubordination and unprofessional conduct.
Obama to campaign with El-Sayed in Detroit as ex-president gets more involved in midterms
Obama is upping involvement in the midterm election. He taped two dozen ads last week for Democratic candidates for governor and Senate that will be released in the coming days and weeks.
Apple notifies Apple Cash users about two upcoming changes
Apple Cash’s terms and conditions have just been updated, and Apple is notifying users about two upcoming changes in particular.
Democrats expand target list as polls point in their favor
Democrats are expanding the number of Republican-held House seats they hope to flip in November as polling moves in their favor ahead of the midterm elections. The Democratic Congressional Campaign Committee announced Monday that it added six candidates to its “Red to Blue” program, bringing the total to 46. The program provides candidates with strategic […]
Trump is clearly trying to buy votes with taxpayer money
President Donald Trump is ramping up his efforts to use taxpayer money and resources to help Republicans win the 2026 midterm elections.
Nutritional countermeasures to spaceflight studied at URI
KINGSTON, R.I. – Oct. 5, 2026 – As humans spend longer periods of time in outer space and venture further from Earth, it’s increasingly important for scientists to learn how varied gravity levels affect muscle function and muscle loss, and how those effects can be counteracted or minimized. Theodoros Pavlidis, a second-year doctoral student who […]
Unfinished Business: Dean Rajan Appointed to Historic Third Term
Madhav Rajan reflects on nine years of leading Chicago Booth and what he wants to accomplish in the years ahead.
‘A five-alarm fire’ confronts President Trump in red-state October blitz
The midterm elections were just two days away the last time a sitting president visited Grand Island, the fourth-largest city in the middle of one of the nation’s most reliably Republican states.
Science Corp. Announces Long-Term (36 Months) Results of PRIMA BCI Clinical Trial Showing Durable Vision Restoration in Blind Patients Suffering from Geographic Atrophy
Science Corporation, the neural engineering and brain-computer interface (BCI) company, today announced long-term (36 months) followup data from its pivotal ...
Top crypto group to pour millions into bipartisan slate of House races after key legislation stalls
WASHINGTON (AP) — A top cryptocurrency campaign organization is unveiling a bipartisan list of House members that it will support in the November midterms, as o
Do More Steps Mean Better Mental Health For Teens?
By HealthDay Staff HealthDay ReporterMONDAY, Oct. 5, 2026 (HealthDay News) — A teenager's daily step count may improve more than their physical health — it may also help protect their mental health. Researchers tracked more than 5,500 adolescents (average age: 12), using Fitbits, brain scans and ...
Is it legal? Trump promises Medicare and ACA checks without Congress ahead of midterm elections
President Trump is promising $90 payments to more than 20 million Medicare seniors and $500 refunds to nearly 1 million ACA enrollees, bypassing Congress and raising legal questions from Democrats.
Democrats release midterms ad featuring family of Epstein victim Virginia Giuffre
The campaign arm working to elect House Democrats released a political advertisement on Monday featuring the family of Virginia Giuffre, who was the first victim of Jeffrey Epstein to go public with allegations of abuse.
KUNC's 2026 midterm election voter guide for Northern Colorado
Everything Northern Colorado voters need to know about the state’s midterm election, including major races, ballot measures, voting deadlines, how to return your ballot, and where to find trusted election resources.
Will Democrats’ midterm wave reach California’s Central Valley? Bernie Sanders rallies the vote
Bernie Sanders rallied hundreds in sweltering Bakersfield heat for Randy Villegas, a progressive long shot in one of the nation's most contested House races.
'Clearly not working': Sam Altman hits AI industry over political spending
In a wide-ranging interview, the OpenAI CEO criticized the flood of AI dollars swamping the midterm elections and suggested a new liability framework is needed for autonomous hacks.
‘Clearly not working’: Sam Altman hits AI industry over political spending
In a wide-ranging interview, the OpenAI CEO criticized the flood of AI dollars swamping the midterm elections and suggested a new liability framework is needed for autonomous hacks.
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
When midterm politics get in the way of governing
After some proposals fell apart in the Senate, both parties will need to figure out to message the failed votes while convincing voters they should be running the show.
Who’s Winning the Battle for Congress?
It’s Oct. 5 — 29 days away from the midterms. Here’s the state of play.
Democrats Expect Record Number of Women in Party in House After Midterm Elections
Democrats are increasingly confident they will have a record number of women serving in the House next year, after backing women in competitive districts they are now positioned to win.
How the Midterms Could Complicate the Supreme Court’s New Term
Even before the justices start their new term on Monday, the court has spent the summer resolving fast-moving requests on election-related disputes.
How the Midterms Could Complicate the Supreme Court’s New Term
Even before the justices start their new term on Monday, the court has spent the summer resolving fast-moving requests on election-related disputes.
How affordability will impact the midterm elections in swing states
It's almost election time in America, and voters in swing states are looking at their wallets — and gas prices — at the ballot box.
Doctors Should Keep an Eye on Your Mix of Medication. If They Don’t, You Should.
There’s a term for reducing unnecessary or harmful drugs: “deprescribing.” Especially as patients age, experts say, it’s important to regularly review the medications they’re taking.
Voters are increasingly using AI chatbots to fact-check and compare candidates
Voters are already voting in the midterms. This year, some voters are trying something new to get ready for the election: asking AI to help research their ballot and even decide who to vote for.
Voters are increasingly using AI chatbots to fact-check and compare candidates
Voters are already voting in the midterms. This year, some voters are trying something new to get ready for the election: asking AI to help research their ballot and even decide who to vote for.
Four ways the midterm elections could go, one month away
Democrats have polls and history on their side. Republicans have money.
3 years after the Oct. 7 attacks, Israel still grapples with its mental health crisis
More than a third of Israelis have shown symptoms of mental health conditions, a report found. Three years after the October 7 attack, the country's health system is still struggling to come to terms with its effects.
How the pursuit of science also serves modernity
Much of science is in the service of modernity, producing remarkable short-term advantages for humans generally at the expense of the rest of the community of life.
Trump takes extraordinary steps to target midterms, alarming critics
Trump's election moves include a redistricting push, seeking to restrict voting and floating a $5,000 payment to every American adult if the GOP wins.
Key to Medicare home health reform is determining program's objective: report
Three possible reforms to Medicare home health are cost-sharing, home health eligibility requirements and optional cash payments, according to a September report from Brookings, a nonpartisan think tank. Which track to choose depends on what the overriding purpose of the program is, the four economist authors say.
OPKO Health (OPK) Sharpens Its Focus, Is It Still A Bargain?
OPKO Health (OPK) has been drawing attention after recent trading moves around its US$1.56 share price, with investors weighing its mixed return profile over the past year against longer term performance trends. For context, OPKO Health’s recent pullback, with a 7 day share price return of down 4.29% and a 30 day share price return of down 4.88% from US$1.56, comes after a stronger 90 day share price return of 4.70% and year to date share price return of 22.83%. The 1 year total shareholder...
True Food Kitchen Initiates Voluntary Chapter 11 Proceedings to Position Business for Long-Term Success
True Food Kitchen (the "Company") today announced that it and certain affiliates have filed voluntary petitions for relief under Chapter 11 of the U.S. Bankruptcy Code in the U.S. Bankruptcy Court for the Southern District of Texas (the "Court").
True Food Kitchen Initiates Voluntary Chapter 11 Proceedings to Position Business for Long-Term Success
/PRNewswire/ -- True Food Kitchen (the "Company") today announced that it and certain affiliates have filed voluntary petitions for relief under Chapter 11 of...
A new Supreme Court term begins with cases on climate change, immigration and gun rights
The Supreme Court begins a new term Monday with significant cases on climate change, religious rights, and immigration | Newsradio 1140 WRVA