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Results for " eva " 4,394 found 🔀 AI-powered Shuffle

Most teens who used AI for mental health support wanted more help

Researchers surveyed 24,132 students in England and found that 2.7% had used general-purpose AI for mental health support during the previous year. Among users who answered the relevant questions, 55.9% rated the support helpful, yet 63.2% wanted additional assistance, with greater unmet needs reported among adolescents experiencing mental health difficulties and social adversity.

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Oct 28 • 7:35 PM EDT • Health • news-medical.net
Gas leak forces road closure, business evacuations in Fort Worth
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Oct 28 • 5:35 PM EDT • Business • wfaa.com
Coral Academy of Science Las Vegas' Windmill Campus Celebrates Middle School’s Five-Star Rating

Coral Academy of Science Las Vegas (CASLV) celebrated Windmill’s Middled School on Tuesday, October 27, for earning a five-star rating in the Nevada Department of Education’s 2025-26 Nevada School Performance Framework (NSPF), the state’s school

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Oct 28 • 5:00 PM EDT • Science • nevadabusiness.com
Washington’s Devan Chandler Long on his journey to ‘Ghosts’

The Anacortes-raised actor returns as the Viking ghost Thorfinn in the "Ghosts" Halloween special, which premieres Thursday on CBS.

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Oct 28 • 4:00 PM EDT • Entertainment • yakimaherald.com
George Mason nursing school gets $15M naming gift

George Mason University will rename its School of Nursing after Arlene Evans and Barry Dewberry following their $15 million gift.

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Oct 28 • 3:51 PM EDT • Business • virginiabusiness.com
Experts Call for a Rigor Reset in Wildfire Social Science

Three veteran wildfire social scientists argue in Fire Ecology that the field's rapid growth demands renewed agreement on methodological rigor, field-based training, and honest evaluation of new technologies.

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Oct 28 • 3:02 PM EDT • Science • bioengineer.org
Fan Favorite Receiver Returns To Bills Practice On Wednesday

After months of ACL recovery, Tyrell Shavers rejoins the Bills following a gutsy postseason performance. His grit and selflessness now face a 21-day evaluation for a roster spot.

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Oct 28 • 2:24 PM EDT • Sports • sports.yahoo.com
Federal Reserve makes interest rate decision ahead of midterms

Federal Reserve policymakers left interest rates unchanged at their October meeting ahead of next week's midterm elections while inflation remains elevated.

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Oct 28 • 2:00 PM EDT • Business • foxbusiness.com
Fresh as the microplastic-laden Sierra snow

For the first time, scientists have measured the microplastic pollution falling on the Sierra Nevada during snowstorms. They found significant amounts even in locations inaccessible by car or by foot.

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Oct 28 • 1:46 PM EDT • Science • news.ucr.edu
NPI awarded National Institutes of Health grant to evaluate implementation of California’s Recess for All law

California law mandates that public elementary and charter schools provide at least 30 minutes of recess time each school day as of school year 2024-25. Implementation was required by California Senate Bill 291, also known as Recess for All, which passed on October 13, 2023 under the leadership of State Senator Josh Newman (D-29). Nutrition Policy Institute director and cooperative extension specialist, Hannah R. Thompson, alongside her colleague Rebecca A.

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Oct 28 • 1:38 PM EDT • Health • ucanr.edu
Sisters family launches seasoning business to thank firefighters after Flat Fire

After evacuating during Flat Fire last year, a Sisters family launched a smoked seasoning company over the summer to give back to local firefighters and first responders. When the Flat […]

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Oct 28 • 1:30 PM EDT • Business • bendbulletin.com
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Prevail Bank names VP-business development officer

JoAnn Draeger has more than 35 years of experience in private banking, mortgage lending, commercial lending and business development.

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Oct 28 • 1:00 PM EDT • Business • wausaupilotandreview.com
FIFA politics around Infantino re-election push Japanese official to resign

GENEVA (AP) — Two-time World Cup coach Takeshi Okada resigned as Japanese soccer federation vice president in protest at the politics around FIFA during Gianni Infantino’s campaign to be re-elected. Japan’s soccer body on Wednesday published Okada’s resignation statement dated last Saturday — 24 hours after the Asian Football Confederation had performed a U-turn by

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Oct 28 • 12:09 PM EDT • Politics • mymotherlode.com
What incarcerated people would like to tell politicians.

What incarcerated people would like to tell politicians.

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Oct 28 • 12:00 PM EDT • Politics • themarshallproject.org
Gevorg Tamamyan: Paediatric Oncologist, System Builder, Transregional Nominee - And A Test For Geneva’s Entrenched Machinery?

Dr Gevorg Tamamyan, an Armenian paediatric oncologist and professor at Yerevan State Medical University, has joined the race for WHO Director-General under a unique cross-regional nomination by the Republic of Botswana. Entering a competitive field of seven candidates as a clinician-academic and the youngest contender (born in 1987), his candidacy introduces a distinct frontline perspective to the 2027-2032 election.

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Oct 28 • 11:35 AM EDT • Health • healthpolicy-watch.news
Three-quarters of NFL football players may end up with CTE

The first estimate of CTE prevalence across the NFL suggests 75 percent of players may suffer from the neurodegenerative disease.

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Oct 28 • 11:32 AM EDT • Science • sciencenews.org
BREAKING: Global Fund Appoints Mark Dybul As Executive Director Amid Mandate And Funding Challenges

Former Global Fund Executive Director Mark Dybul returns to the helm in Geneva facing an unprecedented $5.36 billion funding gap, fraught domestic transitions, and mounting demands to overhaul the global health architecture. While experts welcome his track record, balancing transatlantic rivalries with rising country sovereignty will demand delicate diplomacy and an updated playbook.

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Oct 28 • 10:56 AM EDT • Health • healthpolicy-watch.news
FIFA politics around Infantino re-election push Japanese official to resign

GENEVA (AP) — Two-time World Cup coach Takeshi Okada resigned as Japanese soccer federation vice president in protest at the politics around FIFA during Gianni Infantino’s campaign to be re-elected.

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Oct 28 • 10:23 AM EDT • Politics • wral.com
FIFA politics around Infantino re-election push Japanese official to resign

GENEVA (AP) — Two-time World Cup coach Takeshi Okada resigned as Japanese soccer federation vice president in protest at the politics around FIFA during Gianni Infantino’s campaign to be re-elected.

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Oct 28 • 10:18 AM EDT • Politics • 2news.com
Las Vegas-based advertising agency marks 25 years with new owner, CEO

A former R&R Partners executive takes over the 25-year-old agency with plans to invest in technology, expand into new sectors and strengthen its focus on Southern Nevada businesses.

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Oct 28 • 10:00 AM EDT • Business • reviewjournal.com
5 questions for Penn State basketball this season

Penn State basketball enters the season with a revamped roster and five major questions about its potential.

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Oct 28 • 8:30 AM EDT • Sports • sports.yahoo.com
36 countries to compete in Eurovision 2027 as Ireland, Netherlands stay out over Israel

By Olivia Le Poidevin GENEVA, Oct 28 (Reuters) - Canada will make its Eurovision debut alongside at least 35 other countries at next year's contest, organisers said on Wednesday, with

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Oct 28 • 8:24 AM EDT • Entertainment • centraloregondaily.com
Why Evanilson and Hill give Cherries strong spine

How striker Evanilson and centre-back James Hill have given Bournemouth a strong spine in their run of four wins without conceding a goal.

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Oct 28 • 8:07 AM EDT • Sports • sports.yahoo.com
Xbox Playback feature celebrating your gaming history leaks ahead of 25th anniversary

A new leak suggests Xbox is revamping its annual Year in Review into a brand-new experience called Playback, timed to celebrate 25 years of Xbox.

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Oct 28 • 8:00 AM EDT • Technology • trueachievements.com
Could Saints Trade WR Devaughn Vele?
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Oct 28 • 7:00 AM EDT • Sports • sports.yahoo.com
The World Series lives another day, plus an NFL firesale

The Pulse Newsletter 📣 | This is The Athletic’s daily sports newsletter. Sign up here to receive The Pulse directly in your inbox. Good morning! Shoutout to the Cod Army. Inside: 🤫 Tampa survives 💸 Indy’s open for biz 😳 An unbelievable upset I need to begin this morning with a mea culpa to the Rays. After Brewers rookie Cooper Pratt hit a go-ahead home run in the 12th inning last night, which put Milwaukee three outs away from a World Series title, I started writing this section as if the Brewers would win. And, to be clear, that was for good reason. Entering the...

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Oct 28 • 6:48 AM EDT • Sports • nytimes.com
Inside Melania Trump's secret diplomatic role in the Russia-Ukraine ceasefire deal

Melania Trump spent weeks negotiating between Moscow and Kyiv to broker a localized ceasefire in Oleshky, a devastated city in Ukraine's Kherson region.

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Oct 28 • 6:33 AM EDT • Politics • foxnews.com
Russell Brand gives evidence in UK sex crimes trial

LONDON, Oct 28 (Reuters) - British comedian and actor Russell Brand told a London court on Wednesday that a documentary making allegations about his behaviour had had a devastating effect

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Oct 28 • 6:32 AM EDT • Entertainment • centraloregondaily.com
Agitating for attention, Trump and Bill Maher go at it again

Bill Maher has railed on Trump only half as much as his late-night peers, leaning into various MAGA grievances about the “woke” left and forging a fair-weather friendship with the second-term president.

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Oct 28 • 6:00 AM EDT • Entertainment • latimes.com
Centene, Elevance, Oscar expand ACA footprints as others retreat

Far more counties have only one or two health insurance exchange carriers offering plans for 2027.

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Oct 28 • 6:00 AM EDT • Health • modernhealthcare.com
The U.S. Attorneys Carrying Out Trump’s Election and Grievance Cases

Together, they have pursued cases against the president’s enemies and protesters and amplified false claims of widespread election fraud, often citing thin evidence.

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Oct 28 • 5:02 AM EDT • Politics • nytimes.com
Business briefs: Caesars offers Nevada residents free parking, dining discounts

The participating resorts are Caesars Palace, the Vanderpump Hotel, Harrah’s Las Vegas, Flamingo Las Vegas, the LINQ, Paris Las Vegas, Horseshoe Las Vegas and Planet Hollywood, including its Miracle Mile Shops garage …

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Oct 28 • 5:00 AM EDT • Business • lasvegassun.com
SNHD reports 48 flu hospitalizations, zero deaths since start of season

The Southern Nevada Health District has reported 48 flu hospitalizations in Clark County since Oct. 4, with most cases among adults 50 and older.

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Oct 28 • 12:58 AM EDT • Health • fox5vegas.com
Cary business owners push back on NCDOT project proposal: 'Would be devastating'
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Oct 27 • 11:23 PM EDT • Business • yahoo.com
Cary business owners push back on NCDOT project proposal: 'Would be devastating'

Dozens of small business owners in Cary are concerned about an $84M NCDOT project that could displace longtime stores near Maynard Road and Chatham Street.

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Oct 27 • 11:23 PM EDT • Business • abc11.com
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Developing business association to bring added destination marketing to Sevastopol

A new business association is expected to bring added destination marketing to Sevastopol, one of Door County's most-populated municipalities.

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Oct 27 • 10:14 PM EDT • Business • nbc26.com
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Aguilar feels confident as voting is underway

Nevada Secretary of State talks to UNR students about voter safety, federal interference, and how is office is prepared to take on the "what ifs?"

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Oct 27 • 8:46 PM EDT • Politics • kolotv.com
Who Owns What: The Watermania Waterpark Richmond May Expropriate

[There is often a lack of transparency around land ownership in BC. Who Owns What is an ongoing series by The Realist focused on interesting land ownership stories. Have a suggestion for a future story? Email: howardchai@substack.com.] Earlier this month, CBC and Richmond News reported that the City of Richmond is planning to expropriate Watermania, the waterpark located at 14300 Entertainment Boulevard near the Richmond Ice Centre. The City of Richmond currently leases the property from a private owner — 14300 Entertainment Blvd. Investments Ltd. — and the lease is set to expire in March 2027. According to the reports, the two sides have been unable to agree on terms of the lease renewal and the City has since served a Notice of Expropriation, saying it wants to secure “essential community services,” according to CBC, with outgoing Mayor Malcolm Brodie telling CBC that “Watermania is an important recreation facility for our community, and the city’s goal is to secure its long-term future.” Richmond News added that because the expropriation is not for a linear easement like a sewage line or rapid transit, an inquiry can be requested, and one has been scheduled for November 30 to December 4, according to CBC. What was left out of both stories, however, is who the City would be expropriating Watermania from. According to the Land Owner Transparency Registry, 14300 Entertainment Boulevard is legally owned by 14300 Entertainment Blvd. Investments Ltd. and that numbered company is controlled by a Chinese individual named Hai Feng Zhu, who primarily resides in the Jilin province. The registered address of 14300 Entertainment Blvd. Investments Ltd. is 3899 Cartier Street in Vancouver, a mansion in Shaughnessy that BC Assessment values at $10,423,000. The home at 3899 Cartier Street has previously been tied to Kevin Sun of Sun Commercial by reporter Sam Cooper when he was with the Vancouver Sun in a report noting that Sun had an associate named Hai Feng Zhu who is a director of SunOil Ltd., as confirmed by the company’s filings. Another person mentioned in both the report and filing is Denise She. A search of Hai Feng Zhu in the Land Owner Transparency Registry reveals that Zhu also owns four other properties in British Columbia. The Realist then used the PIDs1 to identify the addresses, finding that the two parcels with PIDs beginning 014 are two parcels that form 1155 Bidwell Street in Vancouver and that the two parcels with PIDs beginning 015 are two parcels that form 1755 Davie Street. 1755 Davie Street is the Best Western Plus Sands, 1155 Bidwell Street is a surface parking lot, and both are held under 0993956 B.C. LTD., which is controlled by Hai Feng Zhu alongside the aforementioned Kevin Sun and Denise She, among others. The Best Western Plus Sands is listed under Sun Commercial’s portfolio and Sun Commercial also previously sold the Richmond Ice Centre to the City of Richmond for $32 million in 2019. Denise She, Peter Cheng De She, and Julia MiMi Yang also control 1078635 B.C. Ltd., which owns 1707 Davie Street, the small retail building that sits between 1755 Davie Street and 1155 Bidwell Street. Governments in British Columbia have a tendency to overpay for real estate, so it’ll be interesting to see how much the City of Richmond pays for Watermania if they do end up expropriating the property. BC Assessment values 14300 Entertainment Boulevard at $49,397,000. The assessed value is dated to July 1, 2025 and is a small decline from the previous assessment of $52,584,000. The rest of this story dives into Sun Commercial and $159 million in sales it made last year to KingSett Capital. Become a paid subscriber for all the details. Subscribe Sun Commercial Sun Commercial is based out of the City Square Shopping Centre at 555 W 12th Avenue in Vancouver, which it acquired in 2019 for $225 million, and also has an office located at 415 Yonge Street in Toronto.

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Oct 27 • 7:37 PM EDT • Entertainment • howardchai.substack.com
Everything Evanston: Fall flavors ramp up spirit, business in Evanston coffee shops

Autumn in Evanston brings seasonal menus and seasonal rushes as coffee shops fill with fall customers. SAMI HELLER: With the weather beginning to fall below 60 degrees, it’s time to ‘fall’ into the season of spooky movies, light sweaters and pumpkin spice. The Daily went into Evanston to see what the season of color-changing foliage...

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Oct 27 • 7:27 PM EDT • Business • dailynorthwestern.com
Animals Starves while the Kardashians Miss the Charts Again

(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) Before we get going, I’d like to offer congratulations to Jonathan Funke, whose suggestion “midflicks” won the poll for what I should call straight-to-streaming films which aren’t big or cinematic enough to go to theaters but seem too expensive for a TV movie. It’s so useful a term, I just used it last week! Now I just need to add this term to my data dictionary! Okay, on to this week’s issue. We’re starting out looking at Netflix/Ben Affleck’s latest crime thriller, Animals. I’ll also look at Disclosure Day heading to Peacock (it did better than you’d remember in theaters...) and a new movie based on toys. Plus, a long-time streaming flop returns for its eighth season...will it finally chart? (No.) Will anyone at Disney care? Probably not. All that, plus another look at new shows landing on streaming on 1-Oct from Reelgood, what streamer hasn’t had a film make the Luminate charts since August, Reacher’s long run on the charts, M_onster: The Lizzie Borden Story’s_ short run, the top shows in 2026 according to Samba TV, all the flops, bombs and misses, and a whole lot more. And I mean that last part: putting this week’s issue together, I assembled OVER 25 images, most of which are bespoke looks I made just for this report. Really, publishing articles like this takes the work of writing two articles: one is the narrative and the other is making charts/graphs. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the week of October 5th to October 11th, 2026. You can find a link to my terminology here.) Subscribe Film - Netflix’s Latest Star-Studded Thriller Goes For Glory The tempting angle for anyone writing about streaming film this month, like yours truly, is to ask, “Is this why Dan Lin lost his job at Netflix?” Take Animals, the Ben Affleck-starring-and-directing, Artists Equity-produced crime thriller that opened on 9-Oct. (Kerry Washington and Gillian Anderson are also in it.) If it did really well, then one could argue that Lin has another success on his resume. If it underperformed, then it’s another example of a Netflix underperformance this year. So where did Animals fall? Kinda in the middle, but that means it’s more “not a hit” than “big hit”. On Nielsen, it opened to 12.0 million hours, and here’s how that stacks up for 2026 films so far this year: Obviously, that’s not great. It’s both under my 15 million opening bar for “fine” for a Netflix film and 20 million bar for “great” opening. It did a bit better on Samba TV, getting to first place. That’s very, very good, though again, looking at the Nielsen data, it probably means that it was a light week overall. Luminate’s data is a bit closer to Samba TV’s, tied for 17th all time for single weeks since May of 2024: To top it off, no one seemed to like it. It has a 33 on Metacritic and only a 5.7 on IMDb. Both of these numbers could have been impacted by the stories about Affleck’s comments about using AI to make the film. Given the controversy, the film might not have been as bad as the ratings suggest, but it’s also not a bullish sign. All to say…yeah, on net this film isn’t a point in Dan Lin’s favor. At this point, Netflix’s slide has been long enough—going on since February—that I’m almost tempted to lower the bar for what a “hit” is on streaming. Post-February of 2026 or so, it seems like straight-to-streaming films just haven’t hit the same heights as they did from 2022 to 2025. Before we head onto the “Quick Hits” for film, I want to shout out a fellow newsletter whose articles I’ve been loving this year, LA Material, a new LA-based news outlet. For just a highlight of my favorite articles since July... I loved this article on Ghost Town, a group on Venice that clears homeless encampments. As a Los Angeleno, obviously I adore their articles on LA parking issues. Their article on illegal parking tickets got the City Council to address the issue! Also check out their article on people parking in medians. Check out their deep dive on what went wrong with the LA Jazz Festival and how it fell apart, or what’s wrong with USC’s finances. Finally, they wrote up a voter guide on voter guides for the LA General Election. So meta! In search of a city? L.A. Material is an independent news outlet covering the people, politics, culture and glorious chaos shaping Los Angeles. L.A. Material brings you intel on the city you can’t get anywhere else. From exploring how Reddit short stories became Hollywood’s hottest commodity to reporting on the survival jobs keeping entertainment workers afloat. And answering, once and for all, why the AMC Burbank escalator is always broken. Through their newsletters, podcast, videos, events, and member community, L.A. Material is designed to help Angelenos connect to Los Angeles and each other. Sign up now for the free weekday newsletter. Quick Notes on Film Steven Spielberg’s latest film, Disclosure Day, came to Peacock on 9-Oct, and I’ll admit that, after pulling its stats, I did a pinch of a double take. As I wrote throughout my deep, deep, deep dive on summer box office/Obsession/Backrooms/IP/superheroes, oftentimes the film media discusses films as “flops” or “misses” or “hits” without clarifying what they specifically mean. Since Disclosure Day didn’t make $250 million in the US or $500 million globally, it was definitely a disappointment by Spielbergian standards, who is the highest-grossing director of all time, and arguably even more ahead in adjusted grosses. But it did make $245 million globally on a $115 million budget, so it isn’t as big of a miss as I remember. That’s still probably not enough to break even in the theatrical window, when you factor in marketing costs…but it’s close. And it grossed a lot more even in the US than some titles with about ten times more coverage. Anyways, lots of preamble to say this one only did 4.5 million hours according to Nielsen, so it did make the charts, but on the low end. Here’s how it stacks up to other Peacock titles: Apple TV (née +) followed up their “success for them” Mayday with Matchbox The Movie. This one doesn’t look like a success even for them, but at least it’s not a miss. Apple/Skydance clearly tried to take advantage of the success of Barbie at the box office—let’s greenlight all the toy properties!!!—but of course, this didn’t make it to theaters. And it stars John Cena, who, as I argued earlier this summer, NEEDS to get his movies back in theaters. Anyways, this one has mixed-to-bad numbers. It missed the Samba TV and Nielsen charts in its first week, but did make Luminate with 7.1 million hours. That’s just enough to not be an outright miss, and about half what Mayday did earlier this summer. Speaking of Apple Studio’s Mayday, it ended up lasting five weeks on Luminate, which isn’t bad for Apple TV. On Nielsen, it had a three-week run, racking up 13.5 million hours total. Again, like Matchbox, the issue is the budget; I doubt that this viewership earned enough to justify that budget. Also, to be clear, neither of these films are “midflicks”; both should have gone to theaters. Toy Story 5 is not hanging around on the streaming charts on Disney+, so it’s not as leggy as either Zootopia 2 or Moana 2, and definitely not in the same class as Encanto. (It did make all the money at the box office, so Disney is going to be fine…) The Breadwinner on Netflix (from Sony) is down to 3.9 million hours in its third week. It only lasted for one week on the Samba TV charts. Netflix’s Doing Life had a smaller-than-normal binge release curve bounce, only going to 7.1 million hours from 6.0 to start, but it made Samba TV at fifth place in its second week. The Netflix documentary, The Widower: Til’ Death Do Us Part, also had a small binge release curve bounce to 6.5 million hours, but did make a second week on Samba TV. Meanwhile, Netflix’s Unabomber fell off after two weeks on Nielsen—which is not great at all—and Demon Slayer fell off after just one week. Over on Luminate, the two smaller titles The Swan: Behind the Mirror and Kill. Bury. Print both fell out of the Luminate top ten charts. The story of library film at the first of the month is the arrival of the Ice Age films on Netflix. Now, here’s a small example of optimizing your library that even Netflix could do better. Say you want to rent/license a new film series from Disney**.** A streamer could pay a big paycheck and then drop each Ice Age film on the exact same day of the month, the fourth of October. That’s one choice. In contrast, the streamer could have released each film one week apart, and make each one a mini-event for folks watching Ice Age films. Or even roll them out monthly. Netflix opted for the former strategy, and as a result, only three of the films made the Nielsen charts this week. The “Miss of the Week” goes to Tubi’s YA-ish horror film_, R.L. Stine’s Pumpkinhead 2_, which didn’t even make the Luminate charts like Tubi films usually do, or, should I say, “used to”? Tubi films, most of which are straight-to-streaming, used to reliably make the Luminate film charts (which only covers straight-to-streaming films), but a Tubi film hasn’t made it since August. The first Pumpkinhead got 1.4 million hours last year according to Luminate. As I wrote about this film before, it seems to be a bit muddled in terms of age: too scary for young kids but probably not scary enough for older kids. Speaking of Luminate, Netflix’s latest doc about a comic (expect more docs about comedians all month), Who Is Martin Mull?, flopped, getting just 200K and 700K hours according to Luminate. Three other film/special misses belonged to Hulu, including a standup special, Jamie Foxx: Take Care of Yourself, Neon’s latest horror film, Hokum, which made $17 million in the US, and a Family Guy Halloween special. (That last one was only 22 minutes, so it’s not a surprise it missed.) Finally, another Netflix standup special missed the charts, Mojo Brookzz: I Know You Lying missed too. I can confirm last week’s misses, most notably Paramount+’s Jackass: Best and Last, MUBI’s Teenage Sex and Death at Camp Miasma and HBO Max’s Evil Dead Burn. Television - I Can’t Visualize Nothing: The Kardashians Story Normally, in the mini-dive essays that open the Streaming Ratings Report, I focus on shows that do well or, at the very least, make the charts. Why? Because as I’ve said time and again, I can’t visualize nothing like, say, the Kardashians’ TV shows. Here’s the TV debuts chart for this week with a missing spot for The Kardashians, whose eighth season just landed on Hulu:

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Oct 27 • 6:17 PM EDT • Entertainment • entertainment.substack.com
Westlake Elevated breaks ground on commercial units small businesses can purchase

Ground was broken Tuesday on Westlake Elevated, a development in Westlake that will give small-business owners the option to buy commercial space instead of leasing it.

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Oct 27 • 5:55 PM EDT • Business • cleveland19.com
"No human at the helm": Delaware plan would let AI agents run entire businesses

Owners of AI-run firms would evade liability for "reckless" AI, US Rep. Comer says.

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Oct 27 • 5:50 PM EDT • Business • arstechnica.com
Neighbors, businesses cry foul over trees removed near Independence Boulevard billboard

The goal is to improve visibility for a billboard along the highway, but business owners say they had no chance to weigh in.

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Oct 27 • 5:25 PM EDT • Business • wsoctv.com
Kelly: A child’s introduction to sports shouldn’t include police

We should be ashamed of ourselves as a country if we can’t figure out how to nurture and develop a 3-year-old soccer protege

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Oct 27 • 4:56 PM EDT • Sports • miamiherald.com
Rays Reveal Revamped World Series Game 4 Lineup vs. Brewers

Facing a 3-0 deficit, Tampa Bay Rays' Kevin Cash shakes up his roster to avoid a World Series sweep against the Milwaukee Brewers.

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Oct 27 • 4:47 PM EDT • Sports • sports.yahoo.com
Vital Skills: Upskilling Genie Code with Healthcare and Life Sciences skills

The blog highlights what Vital Skills, a skill library built by Databricks industry experts, can do for analytical and scientific development with Genie Code. We explain the development and evaluation process, highlight some specific skills, and show how customers can find and use these skills.

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Oct 27 • 3:00 PM EDT • Science • databricks.com
Northern Nevada Public Health holds ‘House of Horrors’ food safety bootcamp

Free event covered how to inspect your own establishment and avoid common violations

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Oct 27 • 2:45 PM EDT • Health • kolotv.com
Canadian firm buys discounted Evanston office building

A venture of Amcor Holdings paid $11.5 million for the 10-story building, a 64% markdown from its sale price eight years ago.

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Oct 27 • 2:31 PM EDT • Business • chicagobusiness.com
Piano bar and restaurant to debut above popular N.J. tavern

According to the owner, the venue will offer a space where diners can experience live music alongside elevated casual dining and craft cocktails.

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Oct 27 • 2:00 PM EDT • Entertainment • nj.com
South Korean Politician Urges President to Play Modern Warfare 4 to Understand 'Devastation' of Potential Invasion

A South Korean politician has urged the country's President to play Call of Duty: Modern Warfare 4 to grasp the potential devastation from a North Korean invasion.

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Oct 27 • 12:39 PM EDT • Technology • ign.com
How Liv Cooke Built A £100 Million Property Business In Her Twenties

Freestyle football champion Liv Cooke built a £100 million property business in her twenties. Now she is investing in entrepreneurs on Property Elevator.

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Oct 27 • 11:49 AM EDT • Business • sports.yahoo.com
Don’t Abolish Business Schools. Make Them Accountable for Impact as well as Value

In response to a recent essay in The New York Times, Wharton Vice Dean Witold Henisz argues that business schools should prepare managers to evaluate both value creation and broader social and environmental impacts.

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Oct 27 • 11:22 AM EDT • Business • knowledge.wharton.upenn.edu
'The Mosquito Bowl' director Peter Berg explores Christlike sacrifice, devastating loss in Netflix WWII film

Filmmaker Peter Berg says his latest World War II drama, The Mosquito Bowl, deepened his understanding of sacrificial love and the devastating human cost of war, particularly the extraordinary bonds

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Oct 27 • 10:59 AM EDT • Entertainment • christianpost.com
Exclusive: Meta director Rohit Patel departs after 8 years to take on Microsoft Office Suite

Rohit Patel is departing Meta after eight years working on AI evaluations and reinforcement learning, TechCrunch has exclusively learned. His startup, Ndoc, aims to take on Microsoft Office Suite.

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Oct 27 • 10:59 AM EDT • Technology • techcrunch.com
Susan Saint James

FILE - Susan Saint James attends the SNL50: The Anniversary Special in New York on Feb. 16, 2025. (Photo by Evan Agostini/Invision/AP, File)

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Oct 27 • 10:35 AM EDT • Entertainment • indianagazette.com
Brevard County HS Sports Weekly Results, Week of Oct. 26-31

Brevard County HS Sports Weekly Results, Week of Oct. 26-31

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Oct 27 • 8:36 AM EDT • Sports • sports.yahoo.com
Are Chelsea finally playing the brand of football Sonia Bompastor wants - and is it WSL title-worthy?

Digital journalist Laura Hunter returns for a second season with a WSL-dedicated column, analysing all the big talking points from across the weekends action; this weeks focus is on Chelseas resurgence and Man Utds swift development under Eva Olid

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Oct 27 • 7:45 AM EDT • Sports • skysports.com
Hot Springs Renaissance Faire returns with Halloween thrills, medieval entertainment

The Hot Springs Renaissance Faire will coincide with Halloween this weekend at the Garland County Fairgrounds, 4831 Malvern Ave., featuring Halloween-themed entertainment, shopping, food and live performances.

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Oct 27 • 5:05 AM EDT • Entertainment • hotsr.com
The gut health category is crowded: How can brands truly stand out?

For formulators, the challenge is no longer simply finding a gut health ingredient, but a product that provides the credible science, relevant benefits and the flexibility to support innovative product formats

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Oct 27 • 3:04 AM EDT • Health • nutraceuticalbusinessreview.com
Intermountain Health breaks ground on Nevada’s first stand-alone children’s hospital

Intermountain breaks ground on Nevada's first stand-alone children's hospital

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Oct 27 • 2:20 AM EDT • Health • kttc.com
Intermountain Health breaks ground on Nevada’s first stand-alone children’s hospital

Intermountain breaks ground on Nevada's first stand-alone children's hospital

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Oct 27 • 2:20 AM EDT • Health • fox5vegas.com
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Intermountain Health breaks ground on Nevada’s first stand-alone children’s hospital

Intermountain breaks ground on Nevada's first stand-alone children's hospital

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Oct 27 • 2:20 AM EDT • Health • wdbj7.com
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Intermountain Health breaks ground on Nevada’s first stand-alone children’s hospital

Intermountain breaks ground on Nevada's first stand-alone children's hospital

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Oct 27 • 2:20 AM EDT • Health • 1011now.com
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Intermountain Health breaks ground on Nevada’s first stand-alone children’s hospital

Intermountain breaks ground on Nevada's first stand-alone children's hospital

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Oct 27 • 2:15 AM EDT • Health • fox5vegas.com
Intermountain Health Groundbreaking on a New Era of Children’s Health for Nevada

Nevada’s first stand-alone children’s hospital groundbreaking marks the community-wide effort to build a stronger pediatric health system. Intermountain Health Felicia and Ben Horowitz Children’s Hospital Model presented at groundbreaking for the Intermountain Health Felicia and Ben Horowitz Children’s Hospital LAS VEGAS, Oct. 27, 2026 (GLOBE NEWSWIRE) -- For Media Use, use the following link for photos/videos: https://securedrop.intermountain.net/securedrop/public.php?service=files&t=010f47fe8a

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Oct 27 • 2:07 AM EDT • Health • finance.yahoo.com
Intermountain Health Breaks Ground on Felicia and Ben Horowitz Children's Hospital

Intermountain Health broke ground on the new Felicia and Ben Horowitz Children's Hospital Monday, celebrating progress in the work to create Nevada's first stan

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Oct 27 • 1:17 AM EDT • Health • news3lv.com
Yeva Margaryan: Journal of Breakthroughs in Medicine and Science Reaches Key Pre-Launch Milestones

Yeva Margaryan: Journal of Breakthroughs in Medicine and Science Reaches Key Pre-Launch Milestones / Alex Adjei, cancer, David Kerr, Fatima Cardoso, James

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Oct 26 • 11:41 PM EDT • Science • oncodaily.com
Here's why data center campaign contributions to Nevada politics are rising

Political contributions from companies with a data center footprint in Nevada are on the rise ahead of a legislative session where the industry is likely to face unprecedented scrutiny.

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Oct 26 • 10:00 PM EDT • Politics • thenevadaindependent.com
Opinion | Everything is political, even if you aren’t

It is easy to feel disconnected from politics. Most of us will never set foot behind the closed doors in Washington D.C., so from a distance, politics seems like something irrelevant to ordinary citizens. That distance can make disengagement seem appealing. With another candidate, election, or bill constantly dominating the news, taking an apolitical stance...

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Oct 26 • 9:50 PM EDT • Politics • dailyiowan.com
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‘Everything is worse’: Trump’s promises not enough in Nevada as voters drown in rising costs
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Oct 26 • 9:02 PM EDT • Politics • cnn.com
Kirby Moore’s first season has been an abject failure

Hindsight being what it is, maybe it should’ve been easier to see this coming. On their third coach in three seasons with their depth pillaged like a Yukon gold rush stake left unprotected, expectations of the Washington State Cougars finishing at or near the top of the revamped Pac-12 were, perhaps, lofty. Not many programs […]

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Oct 26 • 8:20 PM EDT • Sports • sports.yahoo.com
Billy Evans' 'You Can See Everything' shower scene was his idea

Billy Evans — the partner of Theranos founder Elizabeth Holmes — asked the 'You Can See Everything' team: 'Want to film me showering?'

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Oct 26 • 7:37 PM EDT • Entertainment • latimes.com
What Is the Relationship Between Doing Good History and Entertainment?

[Cross-posted from The Tattooed Historian’s Dispatch] What exactly are we doing when we communicate history to the public? Most of us would agree that accuracy matters, evidence matters, context matters, historical rigor matters. But we also live in a world where attention matters (and attention spans are dropping at an alarming rate). Subscribe Whether we’re posting on social media, producing videos, hosting podcasts, giving public talks, or designing museum programs, we’re all competing with countless other demands on people’s time. The public doesn’t simply stumble into history anymore. Now, good history has to find people where they already are. This raises a difficult question: Is making history entertaining part of good historical practice, or is it simply what we must do to remain relevant? “Entertainment” is often treated as the opposite of seriousness. But what do we mean when we use the term itself? Does entertainment mean simplifying the historical record? Does it mean telling compelling stories in a lively manner? Is there a difference between being engaging and being entertaining? And who gets to decide where that line is? Share These questions become even more complicated online. Social media platforms reward attention. Algorithms reward engagement (the positive and the negative). Visibility often depends on producing content that people are willing to click, watch, share, and discuss. What happens when those incentives shape the way history is presented? Can historians work within those systems without letting those systems define the work? Are public audiences being served better than ever before, or are platform incentives changing what kinds of history rise to the surface? These are just a few of the issues that I discuss with John R. Heckman in our latest installment of “Historians Off the Cuff.” Feel free to suggest future topics for us to discuss in the comments section below. Hope you are entertained. LOL Civil War Memory is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe

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Oct 26 • 5:27 PM EDT • Entertainment • kevinmlevin.substack.com
Billy Evans suggested the shower scene in 'You Can See Everything'

"You Can See Everything" director Lance Oppenheim said that Elizabeth Holmes' partner, Billy Evans, suggested he be filmed in the shower.

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Oct 26 • 4:53 PM EDT • Business • businessinsider.com
Water quality health advisory lifted for Eastern Lake in Walton County

The advisory had previously been issued due to elevated bacterial concentrations in the coastal dune lake.

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Oct 26 • 3:37 PM EDT • Health • wjhg.com
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Health district offering free lead testing during National Lead Poisoning Prevention Week

The Southern Nevada Health District wants people with young children at home to know about a free way to check household items for lead.

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Oct 26 • 3:25 PM EDT • Health • fox5vegas.com
Waltham office complex evacuated due to gas leak

Firefighters responded to 1601 Trapelo Road Monday afternoon after reports of a gas main leak, fire officials said.

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Oct 26 • 3:13 PM EDT • Technology • bostonglobe.com
iOS 27.2 is out without the Apple Health revamp

Apple's first major update to iOS 27 has arrived, with iOS 27.2 bringing FaceTime Dual Capture and an Apple Music logo change, but no Apple Health revamp.

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Oct 26 • 2:42 PM EDT • Health • appleinsider.com
VIRAL VIDEO: League officials ask 3-year-old Florida soccer star, family to leave field, saying child ‘played too well’

A viral video with more than 4 million views posted over the weekend shows a 3-year-old soccer prodigy, Nevada, scoring goals against other children on his i9 Sports soccer team in Winter Park.

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Oct 26 • 2:28 PM EDT • Sports • news4jax.com
The 30 best medieval movies of all time, ranked

For those in the mood for knights in shining armor, epic power struggles, and a splash of Arthurian legend.

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Oct 26 • 2:00 PM EDT • Entertainment • yahoo.com
Wilmington Health facility sells for $9.4M

Wilmington Health’s main facility recently sold for more than $9 million. The 66,000-square-foot facility located at 1202 Medical Center Drive was purchased by Charlotte-based real estate investment firm Cedar Square in a $9.4 million sale-leaseback transaction, according to a deed recorded Oct. 21. Wilmington Health will continue leasing the facility, CEO Jeff James told the Business Journal in September. James said the lease term would likely be five years, with most services eventually transferring to a new medical office building under construction in the Midtown Park office area near The Pointe at Barclay. The Wilmington Health facility was originally listed earlier this year at $11.85 million. A Wilmington Health representative did not respond to a request for comment by press time. Steve Hall, vice president of BlueCoast Commercial, represented Wilmington Health in the transaction. “Wilmington Health wanted to unlock the value in its real estate without disrupting a single patient visit, and a sale-leaseback let them do exactly that,” said Hall in a text to the Business Journal Monday. “Cedar Square gets a long-term, absolute net investment anchored by one of the region’s leading physician groups, and Wilmington Health keeps its home on Medical Center Drive while redeploying that capital into care.” The sale marks Cedar Square’s first entry into the Wilmington market, according to Jon Dixon, the firm's managing partner and founder. “We are attracted to Wilmington's growth and what we see as strong long-term fundamentals,” said Dixon in an email Monday. “Population growth, relative affordability, and quality of life make it a compelling market for us. The climate and proximity to the coast are a big part of that appeal.” He added, “We hope to pursue additional opportunities across retail, industrial, medical office and multifamily in Wilmington. We will evaluate opportunities individually and remain disciplined about the properties we pursue. We would like this acquisition to be the beginning of a broader investment presence in Wilmington.” Given the facility’s age, Dixon said the site could eventually be redeveloped, potentially for medical office space or housing. Dixon said recent announcements from UNC Health and Atrium were among the factors behind the firm’s growing interest in Wilmington’s medical-office market. The announcements involve competing proposals for hospital expansion in New Hanover County, which are subject to the state’s Certificate of Need process. “Medical office remains one of the most sought-after asset classes in commercial real estate,” said Hall, “and well-located (medical office buildings) with strong operators are scarce in Southeastern North Carolina.” According to Dixon, Cedar Square describes itself as a boutique, hands-on real estate investment firm that values direct relationships with tenants and the communities where it owns property. “We’re very hands-on, and we like to be in direct contact with all of our tenants and the communities in which we own,” Dixon said. He added, “We’re definitely interested in building a presence with local owners, brokers and businesses or tenants.”

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Oct 26 • 1:58 PM EDT • Health • wilmingtonbiz.com
After the Earthquakes, Venezuela Faces a Longer Health Emergency

Four months after two powerful earthquakes devastated northern Venezuela, aid workers say the country is confronting a deepening health crisis. Chronic illness, disrupted medical care, and psycholo…

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Oct 26 • 12:24 PM EDT • Health • directrelief.org
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Mid-Columbia Ballet prepares for 50th anniversary of "The Nutcracker"

RICHLAND, WA. — For 50 years, the Mid-Columbia Ballet has brought the holiday classic The Nutcracker to audiences in the Tri-Cities. This year, the organization is celebrating that milestone with 144 dancers, new costumes and months of preparation to bring the beloved production to life. The annual performance is a major undertaking for the dancers, instructors and volunteers who work behind the scenes to make the show possible. Rehearsals span 13 weeks, with dancers practicing four days a week for multiple hours at a time.This year’s production will feature new costumes for the Waltz of the Flowers, including a sequence with as many as 25 dancers on stage at once. The show also brings together performers across generations, including adults who have been part of the production for more than 20 years. For Artistic Director Debra Rogo, the preparation begins long before the curtains open.Rogo has been involved with the Mid-Columbia Ballet for 40 years and says planning for The Nutcracker takes place throughout the year. While organizing a production of this size requires significant time and effort, she says watching young dancers grow and develop a passion for ballet makes it all worthwhile. “It’s why I do this,” Rogo said. “It is overwhelming ina good way. To be able to share into their lives and watch them develop a love of this art form and the hard work … it makes me very proud.”Rogo’s decades of involvement reflect the lasting impact the production has had on the local dance community. For many performers, The Nutcracker is more than a seasonal performance. It is an opportunity to build skills, create relationships and become part of a tradition that continues year after year.While the dancers spend weeks rehearsing their routines, a large team of volunteers works behind the scenes to support the production.More than 100 volunteers are involved this year, helping make the performance possible. Their contributions reflect the range of people who come together to support the arts in the Tri-Cities.Randy Haven, a longtime volunteer, says the sense of community is one of the things that makes the experience so special.“The people that you hear volunteering, it’s incredible,” Haven said. He described seeing people from different backgrounds working together backstage, from employees at Hanford to parents raising large families.Haven says that shared commitment creates a family-like atmosphere among the people involved in the production. For Rebecca and Torrie, the Mid-Columbia Ballet has been part of their lives since childhood. Both began dancing with the organization at age seven and have since returned as teachers, helping introduce the next generation to the art form.Their connection to the ballet has continued into their adult lives, creating an opportunity to share their love of dance with younger performers.Torrie now has three daughters performing in The Nutcracker, giving her the chance to watch them experience a tradition that was also part of her own childhood.Being able to see her daughters participate in the production has made the experience especially meaningful, she said.Although audiences can see productions of The Nutcracker in major cities such as New York and Seattle, those involved with the Mid-Columbia Ballet say the local performance offers something distinctive.The community atmosphere allows audiences to experience the production while supporting local performers and the people who dedicate their time to the arts.Rebecca says experiencing a live performance alongside other people is particularly meaningful in a world where so much time is spent looking at screens.She believes live art gives people an opportunity to connect with one another through a shared experience.The ballet’s production also gives local dancers the chance to perform for their community while continuing a tradition that has been part of the Tri-Cities for five decades. When to see ‘The Nutcracker’ in RichlandThe Mid-Columbia Ballet will present its 50th-anniversary production of The Nutcracker Dec. 10 through Dec. 13 in Richland.Tickets go on sale Nov. 1. Audiences can look forward to seeing 144 dancers, new costumes and the work of more than 100 volunteers come together for the holiday production.​COPYRIGHT 2026 BY APPLE VALLEY NEWS NOW. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED.

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Oct 26 • 12:09 PM EDT • Entertainment • applevalleynewsnow.com
📈 Monday data: The bottleneck isn’t intelligence

In the AI Investment Brief today: CapEx updates and lease commitment breakdowns Anthropic co-founder Jack Clark recently said in a speech at the IMF that the singularity has begun: For many years, researchers and science fiction authors have forecast a future in which AI systems drastically increase the pace of overall scientific and technical progress, making things move so quickly that it is hard for humans to keep up. They call this the singularity. I believe that this year we have gained convincing evidence that it has now begun. This follows Anthropic’s claim that in August, 26% of its AI R&D was led by Claude, with a human supervising its work. In October, OpenAI posted 719 math manuscripts1 made by its internal model. Math and coding are two fields where a research loop can close without leaving the desk. But can the loop close in the rest of science? Subscribe The loop is real The idea is not new. Mathematician Irving John Good, who had worked with Alan Turing at Bletchley Park, argued that a machine smarter than us “could design even better machines; there would then unquestionably be an ‘intelligence explosion,’ and the intelligence of man would be left far behind.” The Gödel machine, a self-improving computer that can rewrite its own code better than its prior, was first proposed in 2003. In 2025, researchers at Sakana AI and the University of British Columbia set out to show that this was possible. Their agents iteratively improved their own code through a feedback loop, resulting in gains of 30 pp on SWE-bench and more than 15 pp on Polyglot, testing coding skills beyond Python. The idea has since been tested in other labs. A Gemini-powered agent called AlphaEvolve found a faster matrix multiplication kernel used for training Gemini, speeding up the kernel by 23% and cutting Gemini’s training time by 1%. In China, MiniMax reported that its M2.7 model worked on improving its own agent’s harness, skills, sampling and memory. Over 100 rounds of rewriting led to a 30% gain, per its internal evaluations. In each case, what was being rewritten was not the model itself but everything around it. Is it better than human work? In September this year, in what seemed like a milestone, an AI-built agent proved as good at improving other AI agents as a human-built one. It did that in what appeared to be half the steps. But the result was inconclusive: the differences between runs were greater than the difference between the AI- and human-built agent results. Nonetheless, this is increasing the chatter around recursive self-improvement (RSI) in AI. Google’s Sundar Pichai said that “you have RSI loops along with AI researchers in various aspects of model development.” Sakana AI published a paper on RSI through multi-agent collaboration, finding that after two cycles its system scored 1.2–1.6x better per output token than the base model across four research benchmarks. Ramez Naam challenges that view. He splits AI self-improvement into five overlapping types. The first four describe how autonomous the AI is; so far, only types 1 and 2 have been observed. The fifth type describes accelerating returns, and he notes that greater autonomy doesn’t guarantee a takeoff scenario. Instead, each round of self-improvement would need to deliver at least as much as the last. The results from Sakana, AlphaEvolve and MiniMax above might look like type 3 or type 4 autonomy. But in each case, the AI wasn’t updating its own weights directly, only the ancillary parts — the harness, the memory. And where Claude leads its own R&D, for now a human still supervises.

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Oct 26 • 11:25 AM EDT • Science • exponentialview.co
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Plainwell High School evacuated for ‘unusual odor’ in science hall

Students at Plainwell High School were sent home shortly after classes began Monday morning after a strange odor was reported in the building.

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Oct 26 • 10:19 AM EDT • Science • woodtv.com
Food Safety Risk Assessment: How Scientists Evaluate Chemical and Microbial Hazards

Food safety risk assessment combines evidence about chemical toxicity and microbial hazards with dietary exposure estimates to evaluate potential health effects. Scientists account for combined exposures, susceptible populations, and uncertainty to guide monitoring, regulation, and preventive measures.

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Oct 26 • 9:25 AM EDT • Science • news-medical.net
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AI chatbots can be a valuable health resource for older adults – if they embrace ‘informed skepticism’

AI can help you navigate health information, but evaluating the credibility and quality of responses is key.

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Oct 26 • 8:15 AM EDT • Health • theconversation.com
Inside Business 2026 Top Forty Under 40: Reginald Prevail, Prevail Group

Reginald Prevail is the founder and CEO of Prevail Group LLC.

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Oct 26 • 7:50 AM EDT • Business • pilotonline.com
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Did Elizabeth Holmes and Billy Evans get paid for their documentary?

Nathan Fielder’s documentary turns a dispute over paying its subjects into a central source of tension. Here’s what we know about the proposed deal.

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Oct 26 • 6:00 AM EDT • Entertainment • latimes.com
Olivia Colman, Alexander Skarsgård on 'Wicker' sex scenes, big themes

Colman and co-star Alexander Skarsgård sat down with The Envelope to discuss the unusual (and unusually bawdy) fable of a medieval fisherwoman and the man of her wishes.

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Oct 26 • 6:00 AM EDT • Entertainment • latimes.com
Americans for Prosperity dropped its support for Martina White and other GOP lawmakers over their prevailing-wage vote

The right-leaning group has pulled its endorsements at a time when Republicans in swing districts may need all the help they can get.

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Oct 26 • 5:01 AM EDT • Politics • inquirer.com
Local shops welcome costumed crowds ahead of Halloween

The Volkswagen parking lot was delightfully frightful on a spooky Saturday. Kids of all ages had a chance to test run their Halloween costumes, collect

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Oct 26 • 3:09 AM EDT • Business • evanstonroundtable.com
Franciscan Health receives stuffed animals for pediatric patients across Northwest Indiana

NORTHWEST INDIANA — Pediatric patients in Franciscan Health emergency rooms, pediatric inpatient units and outpatient surgery centers in Michigan City, Chesterton, LaPorte, Dyer and Munster will now have stuffed animals to help make their hospital experience a little more comfortable, thanks to a donation by The Eva Martin Project. Representatives from The Eva Martin Project recently donated more than 1,400 new stuffed animals to the nonprofit Catholic healthcare system during a drop-off at Franciscan Health Michigan City. Each item has a tag with the organization’s logo and a QR code with a personal message on the back. The nonprofit organization

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Oct 26 • 1:10 AM EDT • Health • wimsradio.com
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Local businesses weather the effects of international Geneva cuts

For nearly two years, restaurants, hotels, and other parts of the local economy have grappled with the effects of international Geneva job and budget cuts, particularly around the Nations quarter. Two publicly backed studies are now seeking to quantify the losses.

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Oct 26 • 12:47 AM EDT • Business • genevasolutions.news
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Everything Evanston: Fall flavors ramp up spirit, business in Evanston coffee shops

Autumn in Evanston brings seasonal menus and seasonal rushes as coffee shops fill with fall customers. SAMI HELLER: With the weather beginning to fall below 60 degrees, it’s time to ‘fall’ into the season of spooky movies, light sweaters and pumpkin spice. The Daily went into Evanston to see what the season of color-changing foliage...

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Oct 25 • 11:31 PM EDT • Business • dailynorthwestern.com
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ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals

Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.

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Oct 25 • 11:30 AM EDT • Health • fiercebiotech.com
Evaluating DJ Herz After Bouncing Back from Injury with Nationals

After making his first MLB appearance in nearly two years, what should the Washington Nationals expect from DJ Herz in his third season with the organization?

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Oct 25 • 10:56 AM EDT • Sports • sports.yahoo.com
Evan Mobley on Jarrett Allen: “The team loves it. …

Evan Mobley on Jarrett Allen: “The team loves it. …

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Oct 25 • 9:57 AM EDT • Sports • sports.yahoo.com
Why do dead bodies move and make noise?

The explanation is less zombie apocalypse and more biology.

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Oct 25 • 7:54 AM EDT • Science • popsci.com
New York Giants activate Paulson Adebo; elevate Jalin Hyatt

The New York Giants have made a series of roster moves, including the activation of CB Paulson Adebo and the elevation of WR Jalin Hyatt.

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Oct 25 • 6:55 AM EDT • Sports • sports.yahoo.com