SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " bj " 2,947 found 🔀 AI-powered Shuffle
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
At Issue: Oct. 25 focuses on political advertisements, Rep. John McGuire candidate profile
In less than two weeks, the votes will be in and you will know who will represent your hometown in Congress. But until then, the political advertisements will target you on every device and platform.
She voted for Trump every time. Then came cancer and the bills
Cindy Banda faces mounting medical bills after battling breast cancer.
She voted for Trump every time. Then came cancer and the bills
Cindy Banda faces mounting medical bills after battling breast cancer.
Chicago Bears stadium becomes a political game as midterms near. Can it score for Republicans?
The saga over where the future home of the Chicago Bears has become about more than just sports. For Republicans, and GOP governor nominee Darren Bailey in particular, it represents a political Hail Mary to find a subject that captivates…
“We Have No Business up There” – Gattuso Insists Lazio Are Targeting 40 Points
Gennaro Gattuso urges Lazio to keep their feet on the ground and focus on modest objectives despite leading the Serie A table.Lazio Overcome Parma TestThe Biancocelesti raised their tally to 22 from a...
Las Vegas Raiders owner Mark Davis honored for mental health efforts
The Las Vegas Raiders owner Mark Davis spoke about his support for mental health.
Local business owner faces cleanup after Toledo chemical release
Robert Duling, CEO of Skyline Party Rentals, which is located next to the MC Tank terminal on Progress Avenue, said he’s ready to resume operations.
Politics Unplugged Podcast: Election countdown with Laura Gersony
With Election Day nearing, Arizona’s congressional races are drawing national attention. Arizona Republic reporter Laura Gersony joins Politics Unplugged to break down the high-stakes fights in AZ-01 and AZ-06, where the House majority could be on the line. The conversation examines whether Republican candidates can separate themselves from President Donald Trump as affordability concerns and negative ads dominate the closing days. The episode also looks at outside spending, Elon Musk-backed turnout efforts and the unexpectedly competitive race involving Rep. Eli Crane in northern Arizona. Plus, Dennis Welch and Colin Stanton discuss Arizona’s statewide races, polling, campaign cash and the Valley’s rough sports week.
Ken Block objects to Foulkes' 'October surprise' Costco announcement
Block said that while he too was excited for Costco, he accused board member Helena Foulkes of abusing her position.
NASCAR driver, team investor Brad Keselowski made unsuccessful bid to buy RFK Racing
Brad Keselowski made a bid to buy RFK Racing in its entirety but it was rejected by the other owners of the team.
LingSter Games founder honored by Small Business Development Center
John Ling of LingSter Games was honored as Veteran Small Business Owner of the Year by Finger Lakes SBDC after expanding to a Stoneridge Plaza storefront.
HOMETOWN HEALTH: How pregnancy stress affects fetal brain development
Chronic stress has previously been linked to preterm birth and other complications during pregnancy.
New Email Scam Targets Small Businesses » CBIA
The email uses the subject line “RE: Connecticut Office of the Secretary of the State, Business Services Division.”
Cancer foundation to host health screenings, cooking demo at annual Pink Event
Free health screenings and a cooking demo headline Martinsville’s Pink Event Saturday.
Senior Health Insurance Program navigators available to help during Medicare open enrollment
Chrissy Childers is the lead navigator for SHIP at Rural Health, Inc. This year, she said she’s reminding people to check their Part D plan, since many plans have changed.
HOMETOWN ENTERTAINMENT: Halloween events fill the region this weekend
Busy weekend of Halloween-themed events, including ZOO Boo at Mill Mountain Zoo
Employer Political Activity During the 2026 Midterms: Key FAQs
As the 2026 midterm elections approach, employers may have questions about whether (and how) they can support candidates or political positions. This FAQ addresses common questions about company political activity, communications with employees, mandatory political meetings, and political contributions.
2026 NFL Madrid pregame entertainment announced
The NFL announced that Pablo Sáinz-Villegas and Taylor Momsen will perform the national anthems of Spain and the United States prior to the 2026 NFL Madrid Game.
Selective partnerships define Scottie Scheffler’s off-course business strategy
Scottie Scheffler’s endorsement strategy prioritizes select, values-aligned partners over volume, resulting in $30M annually off the course versus $50M in PGA Tour earnings, a rare split among elite athletes.
Partnership is the key to small business success
Greater Rochester Chamber of Commerce highlights how partnerships accelerate small business success and regional economic growth through collaboration and innovation.
FMOL Health | St. Francis Medical Center hosting annual health fair
FMOL Health | St. Francis Medical Center is hosting their annual Healthy Starts with Hello health fair!
HOMETOWN HEALTH: How expecting mothers should handle this ‘early’ flu season
Doctor says vaccination protects both mother and newborn
Introspection required if EU Inc fails, says start-up lobbyist
European start-ups have a new voice in Brussels. Startups for Europe, created from the merger of lobby groups Allied for Startups and the European Startup Network, is hoping to harness the momentum behind EU-Inc, a campaign that united start-ups and investors behind demands for a new pan-European company regime.At a launch event for the new association in Brussels on October 1, the mood was remarkably upbeat compared to a typical Eurobubble gathering, more Silicon Valley than Schuman roundabout.When asked whether this reflects a feeling that Europe is on the right track, chief executive Serena Borbotti-Frison said it’s a “scary” moment as the continent looks to boost its competitiveness amid a new technological arms race.“What is at stake is quite intense, and the way we can answer is by delivering, but also with hope,” she told Science|Business. “It’s what our industry does. It’s not about identifying a pain point and then saying it’s too hard.”For many in the start-up community, that sense of hope is dwindling. In March, the European Commission presented its proposal for EU Inc, naming its initiative after the grassroots campaign.EU Inc was meant to be a gamechanger: the ability to incorporate within 48 hours for less than €100 and scale up across Europe; a harmonised stock option regime enabling start-ups to compete for talent; and simplified insolvency procedures for innovative start-ups to reduce the cost of failure.However, haggling by EU governments has raised concerns that EU Inc will be stripped of the very features, including stock option harmonisation, that are meant to make it attractive for companies.“I fear we are proving to ourselves that the model doesn’t work,” Borbotti-Frison said of the policymaking process. “Everyone agrees we should have EU Inc. Everyone agrees it’s hard to scale and we need to scale to answer the competitiveness [challenge], and still we cannot deliver? [. . .] What does that say about ourselves?”The Commission has made EU Inc a cornerstone of its single market reform, and has agreed with the European Parliament and the Council of the EU to target an agreement by the end of 2026. However, several points are currently holding up an agreement, including national rules around employee participation in management decisions, and the provision that employee stock options always be taxed at the point of sale. Some EU governments have reportedly pushed back on the Commission’s choice of legal basis, contending that anything related to taxation requires unanimity in the Council.Trade unions have also protested against EU Inc, fearing it will be exploited by companies looking to undermine workers’ rights.“If this doesn’t work, it’s introspection time, on the way our institutions work, maybe the way our lobbies work, and maybe the way the cooperation between them works,” Borbotti-Frison said.“Is it in the national interest? Is it a gap between political will and technical ability to operate? Is it speed? I don't know, but something needs to be fixed.”Ahead of last week’s European Council meeting, EU-Inc campaigners tried a new strategy: appealing directly to EU presidents and prime ministers. In an open letter, they urged EU leaders to “step in and give your negotiating teams a clear mandate to change course and reverse their objections to the Commission’s original proposal.”Lessons from EU-IncLike its predecessors, Startups for Europe will represent national start-up associations, but it is also targeting investors. The founding sponsors are venture capital firm Atomico and EQT, the investor selected earlier this year to manage the €5 billion Scaleup Europe Fund.It also wants to harness the knowledge and cross-border experience of European success stories. “Take the list of the 100 biggest unicorns in Europe. We are speaking to all of them,” Borbotti-Frison said. The association plans to publish a full list of supporters following the Slush tech conference in Helsinki in November.Andreas Klinger and Simon Schaefer, two key figures in the EU-Inc campaign, are both on the board of the new association, and Startups for Europe wants to take the lessons from their campaign.What was unprecedented about EU-Inc was “how rooted it was, and how strong it was in bringing everyone on board behind one clear pain point and solution to fix it,” Borbotti-Frison said. “This is an inspiration for us, and then we need to turn it into something more systematic, more bridged in Brussels, more connected to the policymaking game, and to scale it.”If it’s possible to unite such a broad coalition, it’s because the European start-up ecosystem is now mature, she said. “Maybe it was not ten years ago. Maybe it was not five years ago. But now, it’s mature to speak with one voice.”Open and liberal EuropeThe association plans to campaign on files related to three “pain points,” Borbotti-Frison said: “start and scale in Europe, fundraise and invest in Europe, and making Europe the most innovative continent.”As well as EU Inc, she cited public procurement, the EU’s simplification push, the Savings and Investments Union, and files related to AI adoption and technological sovereignty as priorities for the coming months.What these files have in common is that they relate not to subsidies but to the framework conditions influencing the availability of mostly private, or in the case of procurement, public, funding.Related articlesEmployee participation disagreement delays MEPs’ vote on EU IncCommission urges EU governments not to water down EU IncEU’s ‘ultra-fast’ €5B scale-up fund is set up to win, says its fund managerThe budget dispute over the next Horizon Europe programme will also impact start-ups, which are supported notably through the European Innovation Council. But EU innovation funding is a drop in the ocean compared to venture capital and public procurement budgets.“If competitiveness and innovation are a priority, then the [EU budget] should reflect it,” Borbotti-Frison said. However, she added that the main question is not how much public money is invested, but “how do we create the right conditions for the market to solve the problem?”The Scaleup Europe Fund mixes both approaches, using €1 billion in EU funding to crowd in private investors and address Europe’s lack of large-scale, late-stage growth funds. “It’s a proof of concept. Ideally, then the market will do it itself,” Borbotti-Frison said.Startups for Europe is also focused on bringing an alternative political narrative. Amid competing visions for open, global markets on the one side and a protectionist Europe on the other, it wants to offer “a third voice, to say we can be proudly European and build a strong continent in a liberal economy, open to the world, and global.”It can be tempting, when thinking about how Europe can better support innovation, to look across the Atlantic. But while it’s important to compare statistics to see where Europe needs to catch up, that’s where the comparison should stop, Borbotti-Frison said. “On everything else, we need to do it our own way. We don't have the same history. We don't have the same political model. We don't have the same way of life.”Many of the key files that could benefit the start-up community, including EU Inc and the Savings and Investments Union, rely on closer integration within Europe, making it easier to operate across borders.While the Commission has made deepening the single market a political priority, support at national level is more precarious. The coming months will see pivotal elections in Spain and France, while the German government has also been coming under pressure domestically. In each country, far-right parties have been gaining ground.When asked if she was concerned the political situation could jeopardise this progress, Borbotti-Frison responded: “Of course. I would be lying if I said I wasn’t.” However, she continues to believe that cooperation is the only way forward. “Doing it alone is not the solution. It’s also not who we are, it’s not the model we are building, and it’s not the scale we need.”
From Animal Camouflage to AI: The Evolving Science of Staying Unseen
Nature’s game of hide and seek is entering the age of intelligent machines. A new article in National Science Review traces how animal camouflage, advanced materials and artificial intelligence are converging to reshape the contest between detecting an object and keeping it concealed.
Ramaswamy's ad goes too far weaponizing family in politics
The actions of the campaign of Ohio Republican gubernatorial hopeful Vivek Ramaswamy are disgraceful and continue a progressively nasty tradition of perpetuating gutter politics at any cost, even to the point of dragging an opponent's family trauma into the public square.
Commission announces plan for polar hub to step up research coordination
The European Commission plans to develop an EU polar research hub to strengthen coordination and improve the alignment between science and policy. The objective, according to a Commission official, is to “better connect research, observation and scientific infrastructure, improve access to research resources and strengthen coordination with stakeholders, including Indigenous people.”Announced in a new EU Arctic strategy on October 20, there is little detail yet on how the hub will be implemented, only that it will “reinforce and expand” the European Polar Coordination Office (EPCO), which is hosted and managed by the European Polar Board (EPB) at Umeå University in Sweden. EPCO was born from the EU-PolarNet projects funded through Horizon 2020 and currently coordinates the EU Polar Cluster, a network of EU-funded collaborative polar projects.While the practical details remain to be defined, the decision sends “a clear and positive signal,” said Maria Grigoratou, head of EPCO and executive secretary of EPB. “By reinforcing EPCO, the Commission has an opportunity to build on the legacy of EU-PolarNet 2, strengthen European polar research coordination and expand cooperation with a broader range of Arctic stakeholders,” she told Science|Business.The move has been welcomed by the polar research community. “The polar research hub could play an important role in connecting existing research communities, observation systems and infrastructure, and in bringing scientific knowledge closer to policymaking, in cooperation with local communities and Indigenous people,” said Katrine Moland Hansen, director of operations at Norway’s Nansen Environmental and Remote Sensing Center.But money will be an issue. “It is clear that EPCO will need more resources and structure to function well and to make research reach policymakers,” said Kati Lindström, vice-chair of the Polar Research Committee of the Estonian Academy of Sciences. “European polar research is big if we pool the resources, and it should not only be left to enthusiastic scientists to develop networks of strategic importance in their free time.”The Arctic strategy makes a point of saying that local communities should have a greater involvement in Arctic science. “All EU Arctic research consortia are mandated to invite Indigenous people representatives to participate in projects,” it reads. “The EU also supports research that is directly led by Indigenous communities and address their challenges.”It also underlines the importance of reinforcing collaboration with like-minded partners such as Norway, Iceland, Canada, the UK, Japan and South Korea, as well as deepening its engagement with NATO. This includes the US, with which “the EU is committed to continuing a pragmatic transatlantic engagement based on shared interests and values.”Related articlesViewpoint: Does Europe dare to invest in the Arctic?Anchor Greenlanders in Arctic climate research, experts tell EU ahead of policy updateFor Moland Hansen, this open and inclusive approach to cooperation is encouraging. “The Arctic is also a strong example of why equal participation of associated countries in EU funding instruments matters.”Overall, she finds the new Arctic strategy to be ambitious, timely and comprehensive. “We particularly welcome the recognition that climate change, environmental protection, security, resilience and competitiveness are closely interconnected,” she said. “Research, observations and forecasting capabilities are essential to understanding the rapid changes taking place in the Arctic and addressing these challenges together.”Security focusWhile the Arctic strategy foregrounds security, with pledges to protect undersea cables, boost satellite monitoring, deploy more icebreakers and improve military mobility, the polar community is satisfied that environmental concerns have not been forgotten.“It is inevitable that there is a strong security angle to the EU Arctic strategy, but the impact of climate change and need for climate mitigation and resilience is also strongly recognised and includes a pledge to stay the course on climate commitments,” said Sian Prior, lead advisor to the Clean Arctic Alliance, a coalition of campaigning non-profit organisations.“We need to remember that by the time the next Multiannual Financial Framework comes to an end, in 2034, the polar regions, especially the Arctic region, will be living under a new reality when it comes to ecosystem processes, when it comes to the climate,” Grigoratou went on. “And that will affect any ambition that humans may have in the region.”Lindström agreed. “All aspects of European security are dependent on climate change in the Arctic and consequently, on climate science,” she said. “We cannot close our eyes to issues like energy security, critical minerals, northern shipping routes, dual-use technologies and others. However, it remains to be seen how well the promises to protect the environment and Indigenous rights will hold when faced with critical mineral extraction under the Critical Minerals Act.”
U.K. exam board science specifications reveal gender gap that may influence girls' STEM choices
An absence of women scientists in U.K. exam board specifications for science could be a factor in the disproportionate number of girls dropping STEM subjects at 16 and contribute to the gender gap in ...
Shreveport police seek help identifying suspect in Coburn Supply burglary
Shreveport police are asking for the public’s help identifying a suspect caught on surveillance video breaking into a local business.
Baba nabs $40M series A, backed by FirstMark Capital and CVS Health Ventures, for AI-powered Medicare patient navigation
Applied artificial intelligence company Baba
HOMETOWN HEALTH: New kidney care national plan launched by HHS this week
Kidney disease is one of the nation’s most common chronic diseases.
Abbott Plans to Separate Nutrition Business Into Publicly Traded Company by End of 2027
Abbott Laboratories (NYSE:ABT) has announced plans to spin off its Nutrition division into a separate publicly traded company, with the transaction expected to be completed by the end of 2027, subject to regulatory and corporate approvals. The proposed separation would create an independent business focused on nutritional products while allowing Abbott to concentrate on its medical devices, diagnostics and established pharmaceuticals operations.
HOMETOWN ENTERTAINMENT: Smith Mountain Lake Center to stage Zombie Prom at Westlake Cinema
Zombie Prom takes the stage at Westlake Cinema starting this week.
Heineken taps into home entertainment
The Dutch lager brand has partnered with Brand Innovation Lab, the creative arm of Amazon Ads, to make going out as easy as streaming your favourite show.
Rochester colleges expand mental health workforce training amid shortages
Rochester colleges like Nazareth and St. John Fisher expand mental health training programs to address workforce shortages and improve community access.
Reggie Burrows Hodges remixes the Old Masters for an L.A. homecoming
Reggie Burrows Hodges is the subject of three concurrent L.A. exhibitions at the Getty, the California African American Museum and Art + Practice. These will mark his first-ever solo presentations in his hometown.
Why this Glendale business owner is suing the U.S. government
Mario Ayala said he is trying to keep the business running, but the uncertainty and damage from the raid has taken a toll. Zach Prelutsky reports.
The Brownsville City Commission has approved updates to the City's...
The Brownsville City Commission has approved updates to the City's Entertainment District regulations, adopting an ordinance that repeals and replaces previous ordinances.
PENN Entertainment (NASDAQ:PENN) Stock Price Target Lowered at JPMorgan Chase & Co.
JPMorgan Chase & Co. lowered their price objective on shares of PENN Entertainment from $27.00 to $24.00 and set an "overweight" rating on the stock in a research report on Tuesday.
Amazon uses ‘TNF’ to attract new advertisers, expand ad business
'Thursday Night Football' coverage for Amazon has proven a particularly useful tool to expand its advertising and streaming business.
Opinion: A Bears stadium deal must deliver more than a home for football
Keeping the Bears in Chicago could create opportunities for local businesses, but a stadium deal must also deliver measurable economic returns and inclusion.
HOMETOWN HEALTH: Researchers identify new clues for treating type 2 diabetes
The study's authors say this could be developed into new treatments that could help people regulate their blood sugar.
3 reasons why healthcare organizations ditch tech vendors
Health plans and providers are increasingly inking performance-based contracts with digital health companies to ensure returns on their investment.
List of DVD release dates for Oct. 20 and beyond
Following is a partial schedule of coming movies on DVD. Release dates are subject to change: OCTOBER 20: Masters of the Universe 20: Hadestown: The Musical 20: One Night Only
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)
Proposed New Visa for Home Health Aides and Nursing Assistants: What Healthcare Staffing Companies Need to Know
A new policy proposal published by the Brookings Institution recommends creating a temporary work visa that would let US employers sponsor foreign home health aides, personal care aides, and nursing assistants to help ease a growing shortage of caregivers. The September 29 proposal, authored by Brookings scholar Tara Watson through the Hamilton Project, would create an “H-1D” visa category built specifically for the direct-care workforce, launching as a pilot program of 30,000 visas per year. It would require employers to pay wages near the top of the local market, guarantee workers a minimum number of weekly hours, and contemplate a potential pathway to permanent residence after six years, although implementing that pathway would require additional changes to immigration law. The H-1D is only a proposal at this point. No H-1D legislation has been enacted, and employers cannot currently sponsor workers under this proposed classification. But if the idea gains traction, healthcare staffing companies could find themselves with both a significant recruiting opportunity and a new set of compliance obligations. This Insight walks through the proposal’s general immigration and employment requirements, then turns to the specific opportunities and challenges it could create for staffing firms.
Numerous Escambia County families displaced after Hurricane Isaias, small businesses help rebuild
Local businesses and volunteer organizations provide food, storage and cleanup assistance to families displaced by the storm.
Roanoke leaders say empty storefronts won’t stay empty long as new businesses move in
Locked doors and empty seats. Roanoke City leaders acknowledge rising costs have been a burden on business owners.
RJ Mitte’s mom says there were ‘struggles’ between ‘Breaking Bad’ star and fiancée before his death
RJ Mitte’s mother, Dyna Mitte, says there were ‘struggles’ between the ‘Breaking Bad’ star and his fiancée, Kennedy Suarez, before his death.
Kelly Vlahakis-Hanks Keeps Science Green at ECOS
Chief Executive Kelly Vlahakis-Hanks maintains a keen focus on sustainable manufacturing at ECOS, the company her father founded 60 years ago, building upon his initial idea to create non-toxic alternatives for cleaning. Van Vlahakis, a chemist, founded the manufacturer of green cleaning products at a time when no one was paying attention to ingredients. “He […]
LOVB Miami names Pri Shumate president, builds out business leadership
LOVB Miami has named former Dolphins CMO Pri Shumate president of business operations and former FIFA exec Meg Patten VP/fan experience & marketing, with sports management company Jett Sports serving as its commercial arm ahead of the expansion franchise’s inaugural 2026-27 season.
HOMETOWN HEALTH: New menopause care guidelines aim to improve treatment options
Doctors say awareness of menopause is spreading, but so is misinformation.
The Latest: Democrats gain ground with AAPI adults as trust in GOP fades, poll finds
According to a new AP-NORC/AAPI Data poll, Asian Americans, Native Hawaiians and Pacific Islander adults have become more disillusioned with President Donald Trump and Republicans as the Nov. 3 midterm elections approach, giving Democrats a substantial edge on major issues like the economy and health care
Central Illinois Flea Market vendors explain why they’re in business
The Central Illinois Flea Market wrapped up its season at Peoria Speedway this weekend, giving shoppers one last chance to browse a variety of unique finds.
Medicare Advantage's next golden goose: Special Needs Plans
Chronic Condition Special Needs Plans enrollment has more than doubled since 2024.
Business Starts for Oct. 19, 2026
In June, 1,412 new businesses filed InCorporation paperwork with the Massachusetts Secretary of the Commonwealth, in order to do business in the state. Here is a selection of some of […]
What Kills Schrödinger’s Cat? Scientists Just Ruled Out a 60-Year-Old Theory
Gravity has been proposed as a reason quantum superpositions become difficult to observe in everyday objects. A new experiment challenges one longstanding model of this process. A detector buried deep beneath an Italian mountain has challenged a decades-old theory about why quantum behavior disappears from the world we experience. After 62 days of measurements, researchers
Does Brian Fitzpatrick’s challenger, Bob Harvie, have ‘FBI files’ to release? Pa. legal experts say it’s unlikely.
Republican Rep. Brian Fitzpatrick's campaign has repeatedly called his Democratic challenger the "subject" of an FBI investigation in attack ads. Here's what to know.
Healthcare October 2026
Healthcare insights from Orange County leaders including Hoag, Kaiser Permanente, MemorialCare, Rady Children’s Health and more. An OCBJ Custom Content section.
Leaders of Influence - Insurance 2026
Meet the 18 honorees of OCBJ’s 2026 Leaders of Influence: Insurance, the Orange County professionals guiding risk management and employee benefits.
Trump to sign women’s health executive order Monday
President Trump will sign an executive order Monday creating a women's health division at NIH, backed by First Lady Melania Trump.
Trump to sign women’s health executive order Monday
President Trump will sign an executive order Monday creating a women's health division at NIH, backed by First Lady Melania Trump.
Trump to sign women’s health executive order Monday
President Trump will sign an executive order Monday creating a women's health division at NIH, backed by First Lady Melania Trump.
Trump to sign women’s health executive order Monday
President Trump will sign an executive order Monday creating a women's health division at NIH, backed by First Lady Melania Trump.
Trump to sign women’s health executive order Monday
President Trump will sign an executive order Monday creating a women's health division at NIH, backed by First Lady Melania Trump.
Trump to sign women’s health executive order Monday
President Trump will sign an executive order Monday creating a women's health division at NIH, backed by First Lady Melania Trump.
Browns vs. Ravens not 'personal,' but 'strictly business' for Todd Monken
Todd Monken spent the last three seasons with the Ravens as their offensive coordinator. He's not allowing that to distract him as Browns face them.
Three CT business owners charged with workers’ compensation violations
Three people have been arrested and charged with violations of Connecticut’s workers’ compensation laws, officials said.
Facing Realities: Christian Nationalism, From Local Messages to Political Action - by Jessica Mitchell
Part 3.d -- Faith can guide someone’s vote, their decision to run for office, or their objections to a school board’s action. The question becomes more
Trust TV on Instagram: "“Pilgrimage is a strategy to win votes ahead of 2027 Elections” – Analyst speaks on clerics in politics & the battle for Influence Watch Full Interview: https://youtu.be/oBu4CqReTV0 #trusttvnews #insidethenorth"
1 likes, 0 comments - trusttv_news on October 17, 2026: "“Pilgrimage is a strategy to win votes ahead of 2027 Elections” – Analyst speaks on clerics in politics & the battle for Influence Watch Full Interview: https://youtu.be/oBu4CqReTV0 #trusttvnews #insidethenorth".
I suspected cancer lurked in my body. I hoped this test would ease my fears.
The FDA is expected to approve a new kind of blood test that may allow earlier diagnosis and less invasive, more effective treatment. But doctors warn of drawbacks.
Several Petah Tikva synagogues refuse to host Smotrich, cite objections to politics during services
Some congregants argued that withdrawing the invitation after it had already been extended and publicly announced would be inappropriate, particularly since the synagogue had hosted other speakers.
Have a passion for collecting? You, too, can create a ‘pocket museum.’
But a pocket, or micro, museum is not just a bunch of objects. You need to have a story.
Hackers Use Compromised ConnectWise Credential to Sign In to 173 Microsoft 365 Tenants
Attackers used a compromised ConnectWise Cloud Backup credential for unauthorized sign-ins across 173 Microsoft 365 tenants.
A scoping review of bias in large AI models for medicine and healthcare
Communications Health - A scoping review of bias in large AI models for medicine and healthcare
Huntingdon Health and Rehab wraps up annual Fall Festival
The Fall Festival at Huntingdon Health and Rehab has wrapped up after a full afternoon of family fun.
Knoxville mom turns rivalry pinatas into business, creative outlet amid daughter’s rare diagnosis
Rivalry Row Pinatas let fans take a swing at Tennessee’s opponents at tailgates
Q&A: Design firm CEO says business background, probing into client needs fuels success
For more than 30 years, Berry has had a direct hand in the interior design of everything from corporate headquarters to call centers to hospitals.
Dr. Patrick McGill: Healthy hospitals help drive a healthy Indiana economy
Health care’s impact as an economic driver goes much deeper than direct jobs and spending, in much the same way good schools and housing are intrinsic quality-of-life factors.
Board of Regents: Candidates talk issues ahead of Nov. 3 election
Name: Edie Hooton Office Sought: Colorado Board of Regents, District2 Party: Democrat How should the Board navigate curriculum debates that have become politically polarized? Curriculum decisions must be anchored in the principle of “shared governance,” as defined in Regent Laws. The responsibility for academic excellence lies with the faculty and subject matter experts, as they […]
Show-Me-State Politics: Good news for farmers; midterms near
KY3's Tyler Wayne and KY3 Missouri Capitol Bureau Chief Hannah Falcon discuss this week in Missouri politics.
NBA tells sportsbooks to ban certain bets and parlays: report
The NBA told sportsbook partners in a Friday memo to ban certain types of bets and parlays this season that gamblers used in recent wagering scandals, ESPN reported."There's a balance between ensuring that we are removing problematic bet types but also ensuring that we don't just move activity into the illegal market," NBA executive vice president Scott Kaufman-Ross told ESPN. "Where we landed right now, we think, is the right balance of those two objectives."
WDBJ7+ Hometown Health Special: October 2026
WDBJ7+ Hometown Health Special: October 2026
What a subscription business actually automates when it sets up recurring billing
The word "automatic" in subscription billing can mean two very different things depending on which part of the process it describes.
New SBA lending rules create hurdles for aspiring business owners
Some worry the updated rules to the Small Business Administration's 7(a) loan program would make it harder for some would-be buyers to obtain financing, putting business acquisitions further out of reach.
BVCC's Business Leadership Summit Series: AI
The Blackstone Valley Chamber of Commerce (BVCC) is proud to announce a quarterly leadership series exploring the forces reshaping businesses. The inaugural summit will focus on Artificial Intelligence, designed for […]
M.A. Silva adds two wine industry veterans to sales team
The Santa Rosa cork and glass packaging supplier creates a business development position and hires an account manager with 28 years of experience.
HOMETOWN ENTERTAINMENT: Comedian Brad Williams bringing his “Tall Tales Tour” to Roanoke
Brad Williams brings Tall Tales Tour to Roanoke this month.
Bill Taft: Road construction shouldn’t drive out local businesses
These road projects threaten to undo millions of dollars and years of economic development efforts.
HOMETOWN HEALTH: Epilepsy leading to greater risk of developing dementia before 65, study shows
Researchers said the overall risk of dementia is still low, and more study is needed to understand the link.
I've lived with Microsoft's $6,000 Surface Laptop Ultra, and it's so close to being the best MacBook Pro alternative you can buy
Microsoft's top of the line Windows 11 PC is finally here, and it's giving the MacBook Pro a real good run for its money.
“Light the Horizon” event at Lake Superior Zoo highlights mental health awareness
Lake Superior Zoo hosts mental health awareness event
Closing surveillance detection gaps for emerging digital drug discourse with ontology-enhanced large language models
npj Digital Public Health - Closing surveillance detection gaps for emerging digital drug discourse with ontology-enhanced large language models
Cedar Crossing casino sets ‘soft opening’ for Nov. 19, six weeks ahead of schedule
Cedar Crossing Casino & Entertainment Center will open to the public Thursday, Nov. 19, six weeks earlier than the Dec. 31 opening it had planned, casino leaders announced Thursday, Oct. 15. In July, the CBJ reported that the $275 million casino expected to open in mid-November. Thursday’s announcement sets the date. “I’m proud of our […]
HOMETOWN ENTERTAINMENT: Roanoke-area events this week include outdoor festival, ghost tour and ‘The Wiz’
"The Wiz," Go Fest and other live music events happening in our hometowns over the next several days
Martini Corner businesses react to new Royals ballpark renderings
Shop owners near the new stadium site say the renderings show opportunity
Lexington Walmart pilots new rural health care program
A Walmart in our area is one of just five rural communities in the country testing a new “Health Ambassador” role aimed at making healthcare easier to navigate.
California students post gains in math, science and English in 2025-26
SACRAMENTO, Calif. — California students made gains across key academic and success measures during the 2025-26 school year, with test scores rising in English, math and science while the statewide graduation rate reached a record high of 87.9 percent. For the first time, the state released assessment results and California School Dashboard data together to give families and educators a more complete picture of student performance.English language arts scores increased 0.5 percentage points to 49.3 percent of students scoring proficient or advanced, while math scores rose 1.1 percentage points to 38.4 percent. Science showed the strongest improvement, jumping 3.3 percentage points to 36 percent of students scoring proficient or advanced.The statewide chronic absenteeism rate dropped 1.1 percentage points to 18.3 percent. The suspension rate declined to 2.8 percent, marking the third consecutive year of improvement."At a time when California continues to focus on accelerating learning and closing opportunity gaps, these results provide important evidence that our sustained investments are making a difference," Gov. Gavin Newsom said. "The continued progress we are seeing is a testament to the hard work of students, families and educators across the state—and we will continue working to build on these gains."The percentage of students prepared for college and career increased to 55.2 percent, up 2 percentage points from the previous year. More than 54 percent of graduates completed coursework required for admission to University of California and California State University systems, an increase of 0.9 percentage points."California has made important strides in expanding student supports and opportunities, but the pace of academic improvement reminds us that our work is far from finished," State Superintendent of Public Instruction Tony Thurmond said.Eighth grade students posted the strongest score trends in both English language arts and math. Science performance improved across all tested grades, with the strongest gains at the high school level.African American students demonstrated larger-than-average improvements across English, math and science. Hispanic or Latino students showed larger-than-average improvements in English and math, with positive math score trends across all grades.Students who were socioeconomically disadvantaged made gains across all 3 subjects, including larger-than-average improvements in English and math. Students who were homeless continued to demonstrate gains across grades, with particularly strong improvements in math."We are encouraged to see students making gains across all 3 major assessments and are especially encouraged by the progress of African American students, Hispanic or Latino students, socioeconomically disadvantaged students and homeless youth," said Linda Darling-Hammond, president of the California State Board of Education.The progress comes as California's public school system undergoes significant demographic change. Statewide school enrollment declined to approximately 5.73 million students in 2025-26, nearly 500-thousand fewer students over the past decade.The number of students with disabilities increased approximately 25 percent over the same period, from about 680-thousand to more than 850-thousand students. Graduation rates increased across nearly all student groups, including notable increases for American Indian or Alaskan Native students at 4.3 percentage points and students with disabilities at 3.7 percentage points.In Downey Unified School District, the rate of students demonstrating proficient or advanced grade-level knowledge increased by 2.1 percentage points in English, 2.8 percentage points in math and 4.7 percentage points in science. The district aligned graduation requirements with college admission expectations and invested in inclusive special education practices, expanded career technical education and expanded learning opportunities."The gains Downey Unified is seeing in student assessment results and on the Dashboard are the result of years of focused, consistent work across the district," Superintendent Roger Brossmer said.In Exeter Unified School District, proficiency rates increased by 4.6 percentage points in English, 2.3 percentage points in math and 3.6 percentage points in science. The district placed a strong focus on phonics and the science of reading, particularly in kindergarten through second grade."The gains Exeter Unified is seeing in student assessment results and on the Dashboard are the result of having great people who are focused on the right work, and great students who want to do well," Superintendent Melanie Dorough said.Union Elementary School District saw proficiency rates increase by 1.5 percentage points in English, 2 percentage points in math and 4 percentage points in science. Teachers regularly analyze state and local assessment data to guide instruction, supported by strong core instruction and early literacy strategies."Union Elementary School District's achievement gains reflect a focused, data-driven approach to meeting the needs of every student while fostering a strong sense of belonging, safety and connection," Superintendent Carrie Andrews said.The California Department of Education is examining local results to better understand strategies and conditions associated with stronger student outcomes. The state has made significant investments in recent years, including literacy and math coaching, tutoring, expanded learning opportunities, community schools and universal transitional kindergarten.